CN104666843A - Traditional Chinese medicine composition for treating essential hypotension induced by kidney essence deficiency - Google Patents
Traditional Chinese medicine composition for treating essential hypotension induced by kidney essence deficiency Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition for treating essential hypotension induced by kidney essence deficiency. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal raw materials: prepared rehmannia roots, radix pseudostellariae, acanthopanax, glossy privet fruits, cortex moutan, semen cuscutae, lilies and herba epimedii. The traditional Chinese medicine composition has the functions of invigorating qi and blood and benefiting marrow and filling essence. Clinical application verifies that the traditional Chinese medicine composition is remarkable in curative effect, reliable in effect, mild in drug property and free of toxic and side effects, and the total effective rate is 95.3% and the significant efficiency reaches 52.8%.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of kidney-essence deficiency essential hypotension.
Background technology
Medically, generally the blood pressure of adult is called hypotension lower than 90/60 millimetres of mercury person for a long time, be generally divided into physiological and the large class of pathologic two.Physiological hypotensive, except arteriotony is lower than except above-mentioned value, without any subjective symptoms, without pathological lesion, does not affect the life-span, therefore is not considered as disease.But the essential hypotension in pathologic hypotension, except arteriotony lower than more than except above-mentioned value with dizzy headache, fatigue and weak, lethargy, insomnia forgetfulness, even the symptom such as to faint, often ignored by people.
Primary disease belongs to " dizzy ", " deficiency of vital energy ", " overstrain " category in motherland's medical science, and its pathogenesis is many by insufficiency of vital energy and blood, and brain is become homeless and supported caused clear sun and rise logical having some setbacks, and cloudy air bearing connects obstacle, and negative and positive are become estranged.Etiology and pathogenesis is that natural endowment is not enough, in addition the health preserving day after tomorrow take good care of not good caused by, or overwork or lose blood greatly suddenly, so that blood vessels inanition, the weak anemia of gas, the clear key of heart arteries and veins loses it and supplements nutrition, and is more common in young and middle-aged women and old man.Modern medicine to primary disease without specific treatment.Only adopt anti symptom treatment, strengthen nutrition, take exercises.Motherland's medical science has stronger treatment advantage.
Essential hypotension is divided into the disease types such as Qi and blood deficiency type, kidney-essence deficiency, stagnation of turbid phlegm in middle-JIAO type, sinking of QI of middle-JIAO type by the usual traditional Chinese medical science, and then determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, to reaching desirable therapeutic effect.Wherein kidney-essence deficiency pathogenesis is: the brain being the reservoir of the marrow, the raw marrow of kidney controlling essence storage, if the people of congenital defect, the vital essence of kidney is not filled, or vital essence day worn with age loses, and causes kidney essense loss, marrow can not be given birth to so that brain hollow and hypotension occurs.Patients has dizziness and tinnitus, lethargy, forgetfully sleeps less, the soreness of waist.
Yang Wei, adds and subtracts by LIUWEI DIHUANG TANG for kidney-essence deficiency in article " the routine observation of curative effect of tcm syndrome differentiation and treatment essential hypotension 46 " (Colleges Of Traditional Chinese Medicine Of Shanxi's journal, 2006,7 (6): 42-43).Prescription: Radix Rehmanniae Preparata 15g, Rhizoma Dioscoreae 18g, Fructus Corni 15g, Poria 15g, Cortex Moutan 15g, Arillus Longan 15g, Carapax et Plastrum Testudinis 15g, Fructus Lycii 15g, Rhizoma Polygonati 15g, Semen Persicae 12g, Fructus Viticis 10g, Fructus Aurantii 12g.
Ge Sujuan, adds and subtracts by LIUWEI DIHUANG TANG for kidney-essence deficiency in article " the routine clinical observation of differentiation of tcm essential hypotension 60 " (combination of Chinese and Western medicine cardiovascular and cerebrovascular disease magazine, 2013,11 (4): 426-427).Prescription: Radix Rehmanniae Preparata 15g, Rhizoma Dioscoreae 18g, Fructus Corni 15g, Poria 15g, Cortex Moutan 15g, Arillus Longan 15g, Carapax et Plastrum Testudinis 15g, Fructus Lycii 15g, Rhizoma Polygonati 15g, Fructus Aurantii 10g, is decocted in water for oral dose, every day 1 dose, and point 2 morning and evening decoction being taken warmly 2 weeks are 1 course for the treatment of.
Lin Zhenhui etc. at article " tcm syndrome differentiation and treatment essential hypotension 83 example ", (Colleges Of Traditional Chinese Medicine Of Fujian's journal, 1999,9 (1): 12 ~ 13), for marrow deficiency, add and subtract by side's placenta pill.
Above-mentioned testing program all adopts medicine typing opinion to control, but the case load related to is not mentioned or less, representativeness is not strong, cannot to investigate the therapeutic effect of such scheme and safety, and the current randomized controlled trial adopting Chinese medicine to treat kidney-essence deficiency essential hypotension is targetedly less, it is serious that tonic abuses phenomenon, needs clinical treatment medicine targetedly.
Summary of the invention
Inventor is according to oneself tcm clinical practice experience for many years, sum up the Couple herbs of traditional proved recipe and case, for kidney-essence deficiency essential hypotension, there is the opinion of oneself uniqueness, specific to this disease type hypotension, think in conjunction with clinical manifestation, should weigh comprehensively, treatment is with benefiting vital QI and blood, and beneficial marrow and benefitting semen is main.For this reason, a kind of Chinese medicine composition for the treatment of kidney-essence deficiency essential hypotension is provided.Said preparation can not only improve hypotension state, and can regulate the immunologic function of body, fundamentally improves the deficient state of body, thus makes blood pressure recover normal.
The technical solution used in the present invention is as follows:
A kind of Chinese medicine composition for the treatment of kidney-essence deficiency essential hypotension: it is made up of following traditional Chinese medicine raw: Radix Rehmanniae Preparata, Radix Pseudostellariae, Radix Et Caulis Acanthopanacis Senticosi, Fructus Ligustri Lucidi, Cortex Moutan, Semen Cuscutae, Bulbus Lilii, Herba Epimedii.
Preferably, a kind of Chinese medicine composition for the treatment of kidney-essence deficiency essential hypotension: it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Radix Rehmanniae Preparata 21-27 part, Radix Pseudostellariae 16-21 part, Radix Et Caulis Acanthopanacis Senticosi 17-23 part, Fructus Ligustri Lucidi 13-18 part, Cortex Moutan 9-15 part, Semen Cuscutae 11-17 part, Bulbus Lilii 12-15 part, Herba Epimedii 8-13 part.
Further preferably, a kind of Chinese medicine composition for the treatment of kidney-essence deficiency essential hypotension: it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Radix Rehmanniae Preparata 22-25 part, Radix Pseudostellariae 17-20 part, Radix Et Caulis Acanthopanacis Senticosi 18-20 part, Fructus Ligustri Lucidi 14-17 part, Cortex Moutan 11-15 part, Semen Cuscutae 13-16 part, Bulbus Lilii 12-15 part, Herba Epimedii 9-12 part.
The preferred version that inventor optimizes further: a kind of Chinese medicine composition for the treatment of kidney-essence deficiency essential hypotension: it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Radix Rehmanniae Preparata 23 parts, Radix Pseudostellariae 18 parts, Radix Et Caulis Acanthopanacis Senticosi 18 parts, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 12 parts, Semen Cuscutae 15 parts, Bulbus Lilii 13 parts, Herba Epimedii 11 parts.
Fang Zhong: Radix Rehmanniae Preparata nourishing YIN and supplementing blood, beneficial essence fill out marrow, supplements base substance needed for essence and blood; Radix Pseudostellariae replenishing QI to invigorate the spleen, promote the production of body fluid and moisturize, two medicines are betrothed to 5 mutually, and supplement the base substances such as essence, gas, blood, vigorate qi and replenish the blood, the prosperous then hemopoietic of gas, beneficial essence fills out marrow, and essence and blood turns mutually, and blood pressure, from liter, is monarch drug.Fructus Ligustri Lucidi is cool in nature, and color green grass or young crops is black, fills out the essence of kidney, the body of tonifying liver; The pungent temperature of Herba Epimedii, the sun of the kidney invigorating, bone and muscle strengthening; Semen Cuscutae is put down, tonifying both YIN and YANG, and merit is apt to controlling nocturnal emission with astringent drugs, and three medicines are ministerial drug altogether, tonifying kidney-yin invigorating kidney-YANG, and principal drug assistance benefit essence fills out marrow, and to mend congenital deficiency, all diseases of soreness of the waist and knees, dizziness and tinnitus are all separated.Radix Et Caulis Acanthopanacis Senticosi both can have been helped monarch drug replenishing QI to invigorate the spleen and to have been held concurrently the kidney invigorating, had again effect of promoting blood circulation to restore menstrual flow, adjust along passages through which vital energy circulates assist a ruler in governing a country all medicines return through, also can calm the nerves, be adjuvant.Bulbus Lilii GUIXIN warp, clears away heart-fire to calm the nerves, and is adjuvant drug.Cortex Moutan bitter cold, entering heart channel can heat clearing and blood cooling, and entering Liver Channel and invigorate blood circulation and heat clearing away, help Liver and kidney essence and blood to turn mutually, is also adjuvant.We hold concurrently regulation of mental activities liver lung kidney pair, and spiritlessness and weakness, palpitation and amnesia, dysphoria with feverish sensation in the chest palms and soles, night sweat such as to be slept less at the symptom, Be very effective.
In Chinese Pharmacopoeia, the pharmacological activity present Research of the present invention's medical material used is as follows.
Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.Function cures mainly: nourishing YIN and supplementing blood, and beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
Radix Pseudostellariae: sweet, micro-hardship is flat.Return spleen, lung meridian.Function cures mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Radix Et Caulis Acanthopanacis Senticosi: pungent, micro-hardship, temperature.Return spleen, kidney, heart channel.Function cures mainly: replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.For deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, insomnia and dreamful sleep.
Fructus Ligustri Lucidi: sweet, bitter, cold.Return liver, kidney channel.Function cures mainly: nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
Cortex Moutan: bitter, pungent, is slightly cold.GUIXIN, liver, kidney channel.Function cures mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Semen Cuscutae: sweet, temperature.Return liver,kidney,spleen warp.Function cures mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Bulbus Lilii: sweet, cold.GUIXIN, lung meridian.Function cures mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
Herba Epimedii: acrid, sweet, warm.Return liver, kidney channel.Function cures mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture.
The Chinese medicine composition for the treatment of hypopiesi provided by the present invention, can be prepared into pulvis oral; Also each component directly can be mixed and made into coarse powder, the effective ingredient extracted in coarse powder makes extractum, utilizes extractum to be prepared into oral capsule, pill, tablet, powder, oral liquid, can also be prepared into other dosage form being suitable for treating hypopiesi.
When making dispersant or big honeyed pills, the crude drug amount that patient takes is effective compared with great talent, and big honeyed pills takes inconvenience, inventor considers the factors such as recipe quantity, pharmaceutical properties, medication object, easy to use, cost of manufacture, preferably make oral capsule, directly be mixed and made into coarse powder by each component, the effective ingredient extracted in coarse powder makes extractum, utilizes extractum to be prepared into oral capsule.
The preparation method of Chinese medicinal composition capsules agent of the present invention, mainly comprise the steps: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as the 4-6 times amount of medical material weight, soak 3-4 hour, then 2.0-2.5 hour is decocted, second time adds water as the 3-5 times amount of medical material weight, decoct 1.0-1.5 hour, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.05-1.20, adding ethanol makes the volume ratio of alcohol content be 45-60%, stir, hold over night, filter, filtrate reduced in volume reclaims ethanol, be condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts decoction alcohol precipitation method to extract whole part.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, do not occur toxic and side effects, total effective rate 95.3%, obvious effective rate reaches 52.8%.Refer to as follows.
1. object of study: selection the court's June 103-2014 years in October, 2013, routine patient entered group.Be divided into two groups at random, treatment group 53 example, man 14 example, female 39 example; 23 years old ~ 55 years old age, average 35 years old; Medical history 1 year ~ 6 years.Matched group man 14 example, female 36 example; 24 years old ~ 50 years old age, average 36 years old; Medical history 1 year ~ 6 years.Two groups of physical data comparing difference not statistically significants (P > 0.05), have comparability.
2. case selection standard: 1. continuous measurement 3d brachial arterial pressure is lower than 90/60mmHg (12/8kPa); 2. clinical condition is shown in: have a dizzy spell, soreness of the waist and knees, spiritlessness and weakness, palpitation and amnesia, dysphoria with feverish sensation in the chest palms and soles, night sweat sleeps less, red tongue tongue is few, thready and stringy pulse; 3. check without organ diseases such as liver, spleen, lung, kidneys; 4. the pathological changes such as orthostatic hypotension, secondary hypotension is got rid of.
3. Therapeutic Method: (1) treatment group: take Chinese medicinal capsule prepared by the embodiment of the present invention 1, every 0.4g, twice daily, each 3-4 grain; (2) matched group: take ATP capsule (20mg, Community in Baiyunshan, Guangzhou pharmaceutical manufacturing) every day 3 times, each 2, Ephedrine Tablet (25mg) every day 3 times, each 1, two groups all serve on month.
4. efficacy assessment standard: 1. effective: clinical symptom disappearance, blood pressure > 100/70mmHg; 2. effective: clinical symptom relief or disappearance, blood pressure > 90/60mmHg; 3. invalid: clinical symptoms without improvement, blood pressure < 90/60mmHg.
5. results and analysis:
Two groups of patient treatment outcome compare: at the end for the treatment of, and two groups of therapeutic effect compare, and obvious effective rate and the effective percentage for the treatment of group are obviously better than matched group, and difference has statistical significance (P < 0.05).Results contrast is in table 1.
Table 1 three groups of patient treatment outcome compare, routine %
Above clinical efficacy result prompting: Chinese medicinal capsule of the present invention is in treatment kidney-essence deficiency essential hypotension, and have curing protrusion effect, curative effect is all better than matched group.
Safety evaluatio: the hypotensive whole observation case of Chinese medicinal capsule treatment of the present invention, does not find that blood pressure rises to hypertension dividing value; Do not find toxicity, side effect and untoward reaction; Matched group occurs that 4 routine blood pressures rise to the situation of hypertension dividing value.Blood, urine, stool routine examination, hepatic and renal function, electrocardiogram etc. before and after two groups of case administrations, safety observations index is without significant change.
Detailed description of the invention
The detailed description of the invention of form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1
Prescription: Radix Rehmanniae Preparata 23 parts, Radix Pseudostellariae 18 parts, Radix Et Caulis Acanthopanacis Senticosi 18 parts, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 12 parts, Semen Cuscutae 15 parts, Bulbus Lilii 13 parts, Herba Epimedii 11 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 5 times amount of medical material weight, soak 4 hours, then decoct 2.0 hours, second time adds water as 4 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.10, adds ethanol and makes the volume ratio of alcohol content be 50%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 2
Prescription: Radix Rehmanniae Preparata 22 parts, Radix Pseudostellariae 17 parts, Radix Et Caulis Acanthopanacis Senticosi 18 parts, Fructus Ligustri Lucidi 14 parts, Cortex Moutan 11 parts, Semen Cuscutae 13 parts, Bulbus Lilii 12 parts, Herba Epimedii 9 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 6 times amount of medical material weight, soak 4 hours, then decoct 2.5 hours, second time adds water as 5 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.15, adds ethanol and makes the volume ratio of alcohol content be 55%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 3
Prescription: Radix Rehmanniae Preparata 25 parts, Radix Pseudostellariae 20 parts, Radix Et Caulis Acanthopanacis Senticosi 20 parts, Fructus Ligustri Lucidi 17 parts, Cortex Moutan 15 parts, Semen Cuscutae 16 parts, Bulbus Lilii 15 parts, Herba Epimedii 12 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 6 times amount of medical material weight, soak 4 hours, then decoct 2.0 hours, second time adds water as 5 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.20, adds ethanol and makes the volume ratio of alcohol content be 60%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 4
Prescription: Radix Rehmanniae Preparata 22 parts, Radix Pseudostellariae 17 parts, Radix Et Caulis Acanthopanacis Senticosi 20 parts, Fructus Ligustri Lucidi 17 parts, Cortex Moutan 13 parts, Semen Cuscutae 14 parts, Bulbus Lilii 12 parts, Herba Epimedii 10 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 4 times amount of medical material weight, soak 3 hours, then decoct 2.5 hours, second time adds water as 4 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.05, adds ethanol and makes the volume ratio of alcohol content be 45%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 5
Prescription: Radix Rehmanniae Preparata 25 parts, Radix Pseudostellariae 19 parts, Radix Et Caulis Acanthopanacis Senticosi 18 parts, Fructus Ligustri Lucidi 14 parts, Cortex Moutan 13 parts, Semen Cuscutae 13 parts, Bulbus Lilii 15 parts, Herba Epimedii 12 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 4 times amount of medical material weight, soak 3 hours, then decoct 2.0 hours, second time adds water as 4 times amount of medical material weight, decocts 1.0 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.10, adds ethanol and makes the volume ratio of alcohol content be 58%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 6
Prescription: Radix Rehmanniae Preparata 21 parts, Radix Pseudostellariae 16 parts, Radix Et Caulis Acanthopanacis Senticosi 17 parts, Fructus Ligustri Lucidi 13 parts, Cortex Moutan 9 parts, Semen Cuscutae 11 parts, Bulbus Lilii 12 parts, Herba Epimedii 8 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 4 times amount of medical material weight, soak 3 hours, then decoct 2.0 hours, second time adds water as 3 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.12, adds ethanol and makes the volume ratio of alcohol content be 54%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 7
Prescription: Radix Rehmanniae Preparata 27 parts, Radix Pseudostellariae 21 parts, Radix Et Caulis Acanthopanacis Senticosi 23 parts, Fructus Ligustri Lucidi 18 parts, Cortex Moutan 15 parts, Semen Cuscutae 17 parts, Bulbus Lilii 15 parts, Herba Epimedii 13 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 6 times amount of medical material weight, soak 4 hours, then decoct 2.5 hours, second time adds water as 5 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.20, adds ethanol and makes the volume ratio of alcohol content be 60%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 8
Prescription: Radix Rehmanniae Preparata 25 parts, Radix Pseudostellariae 20 parts, Radix Et Caulis Acanthopanacis Senticosi 20 parts, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 15 parts, Semen Cuscutae 15 parts, Bulbus Lilii 15 parts, Herba Epimedii 10 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 5 times amount of medical material weight, soak 4 hours, then decoct 2.5 hours, second time adds water as 5 times amount of medical material weight, decocts 1.5 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.15, adds ethanol and makes the volume ratio of alcohol content be 60%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Embodiment 9
Prescription: Radix Rehmanniae Preparata 21 parts, Radix Pseudostellariae 17 parts, Radix Et Caulis Acanthopanacis Senticosi 19 parts, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 12 parts, Semen Cuscutae 17 parts, Bulbus Lilii 12 parts, Herba Epimedii 12 parts.
Preparation method: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as 4 times amount of medical material weight, soak 3 hours, then decoct 2.5 hours, second time adds water as 3 times amount of medical material weight, decocts 1.0 hours, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.12, adds ethanol and makes the volume ratio of alcohol content be 50%, stirs, hold over night, filter, filtrate reduced in volume reclaims ethanol, is condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
Claims (6)
1. treat the Chinese medicine composition of kidney-essence deficiency essential hypotension for one kind: it is characterized in that it is made up of following traditional Chinese medicine raw: Radix Rehmanniae Preparata, Radix Pseudostellariae, Radix Et Caulis Acanthopanacis Senticosi, Fructus Ligustri Lucidi, Cortex Moutan, Semen Cuscutae, Bulbus Lilii, Herba Epimedii.
2. Chinese medicine composition as claimed in claim 1: it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Radix Rehmanniae Preparata 21-27 part, Radix Pseudostellariae 16-21 part, Radix Et Caulis Acanthopanacis Senticosi 17-23 part, Fructus Ligustri Lucidi 13-18 part, Cortex Moutan 9-15 part, Semen Cuscutae 11-17 part, Bulbus Lilii 12-15 part, Herba Epimedii 8-13 part.
3. Chinese medicine composition as claimed in claim 2: it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Radix Rehmanniae Preparata 22-25 part, Radix Pseudostellariae 17-20 part, Radix Et Caulis Acanthopanacis Senticosi 18-20 part, Fructus Ligustri Lucidi 14-17 part, Cortex Moutan 11-15 part, Semen Cuscutae 13-16 part, Bulbus Lilii 12-15 part, Herba Epimedii 9-12 part.
4. Chinese medicine composition as claimed in claim 3: it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Radix Rehmanniae Preparata 23 parts, Radix Pseudostellariae 18 parts, Radix Et Caulis Acanthopanacis Senticosi 18 parts, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 12 parts, Semen Cuscutae 15 parts, Bulbus Lilii 13 parts, Herba Epimedii 11 parts.
5. the Chinese medicine composition as described in as arbitrary in claim 1-4: it is characterized in that it makes peroral dosage form, as pulvis, pill, tablet, powder, oral liquid etc.
6. the Chinese medicine composition as described in as arbitrary in claim 1-4: it is characterized in that it makes capsule, the preparation method of this capsule mainly comprises the steps: each medicinal raw material taking recipe quantity, merge, decoct with water twice, first time adds water as the 4-6 times amount of medical material weight, soak 3-4 hour, then 2.0-2.5 hour is decocted, second time adds water as the 3-5 times amount of medical material weight, decoct 1.0-1.5 hour, collecting decoction, when being evaporated to 60 DEG C, relative density is 1.05-1.20, adding ethanol makes the volume ratio of alcohol content be 45-60%, stir, hold over night, filter, filtrate reduced in volume reclaims ethanol, be condensed into thick paste, add appropriate amount of auxiliary materials, mixing, dry, prepare by Chinese medicinal capsule common process.
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| CN102698062A (en) * | 2012-05-26 | 2012-10-03 | 苑丕吉 | Chinese herbal medicine for treating hypotension |
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| CN102698062A (en) * | 2012-05-26 | 2012-10-03 | 苑丕吉 | Chinese herbal medicine for treating hypotension |
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| 劳国平: "补肾汤治疗原发性低血压38例", 《实用中医药杂志》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267130A (en) * | 2016-10-12 | 2017-01-04 | 孙爱玲 | A kind of Chinese medicine composition treating kidney-essence deficiency essential hypotension |
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