CN106620079A - Ointment for treating scars and acne - Google Patents

Ointment for treating scars and acne Download PDF

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Publication number
CN106620079A
CN106620079A CN201710022035.9A CN201710022035A CN106620079A CN 106620079 A CN106620079 A CN 106620079A CN 201710022035 A CN201710022035 A CN 201710022035A CN 106620079 A CN106620079 A CN 106620079A
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Prior art keywords
parts
ointment
acne
semen lini
herba hedyotidis
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CN201710022035.9A
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Chinese (zh)
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江海波
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Individual
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Individual
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Priority to CN201710022035.9A priority Critical patent/CN106620079A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/55Linaceae (Flax family), e.g. Linum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the technical field of human face skin drugs and particularly relates to an ointment for treating scars and acne. The ointment is prepared from, by weight, 5-10 parts of cold-pressed linseed oil, 3-5 parts of spreading hedyotis herb extraction liquid, 5-10 parts of C18 fatty alcohol, 3-5 parts of stearic acid, 2-5 parts of glycerin, 5-10 parts of aloe extract liquid and 5-8 parts of deionized water. The ointment is natural, non-irritant, harmless to face skin cells and capable of moisturizing, inhibiting bacteria, treating the acne and repairing physical trauma to a certain degree.

Description

A kind of ointment for treating cicatrix and acne
Technical field
The invention belongs to human facial skin's field of pharmaceutical technology, and in particular to a kind of ointment for treating cicatrix and acne.
Technical background
Existing skin care drug is divided into chemical facial treatments product and natural facial treatments product, chemical facial treatments product There is degreasing power strong, zest is larger, life-time service is easily destroyed skin nature water conservation barrier, causes percutaneous moisture loss exception Increase, produce skin of face be dried, it is coarse the problems such as, select natural, nonirritant surfactant system and addition Become the irritating main path of the chemical facial products of reduction with natural skin care conditioning ingredients;
Now, the ultraviolet of external environment condition causes the Erythema and inflammation of facial skin, dry air easily to make face Skin hydropenia, the wound of some physics scar on skin of face, the composition of existing natural facial treatments product is mostly It is difficult to the effect for repairing physical trauma and treatment acne while face moisture-keeping and nursing is ensured, therefore, how to adopt The composition of natural no stimulation is made facial treatments medicine to carry out face reparation physical trauma, while moisturizing, can eliminate skin The new face cleaning products of effect such as skin sterilization, antibacterial, antiinflammatory, decomposition toxin, treatment acne become problem to be solved.
The content of the invention
It is an object of the invention to provide a kind of ointment for treating cicatrix and acne, the characteristics of it has natural, non-stimulated, To facial Skin Cell not damaged, while the work with moisturizing, certain reparation physical trauma and moisturizing, antibacterial, treatment acne With.
To achieve these goals, the technical solution used in the present invention is:A kind of moisturizing and the cleansing milk for the treatment of acne, It is made up of following raw materials according by weight:5-10 part cold pressed flax seed oils, 3-5 part Herba Hedyotidis Diffusae extracts, 18 fat of 5-10 parts Fat alcohol, 3-5 part stearic acid, 2-5 part glycerol, 5-10 parts Aloe extraction solution and 5-8 part deionized waters;Each raw material is mixed, heating To 50 DEG C so as to melt, after stirring, subpackage is made.
The raw material is by weight:8 parts of cold pressed flax seed oils, 2 parts of Herba Hedyotidis Diffusae extracts, 7 part of 18 fatty alcohol, 4 Part stearic acid, 3 parts of glycerol, 6 parts of Aloe extraction solution and 7 parts of deionized waters.
The preparation process of the cold pressing Semen Lini is:
1) harvesting of Semen Lini, screening;
2) impurity and shelling are cleared up;
3) Semen Lini after shelling is put into air pressure tank squeezing 20-40min, temperature 0-5 DEG C, pressure 10-40kPa, oil yield For 8%-10%;
4) filter:Semen Lini oil after squeezing is passed through into filter-cloth filtering remove impurity;
5) clarify:Semen Lini oil after filtration is stood, edible vegetable oil is taken and is Semen Lini oil.
The preparation method of the Herba Hedyotidis Diffusae extract is:Herba Hedyotidis Diffusae is crushed, in the condition of solid-liquid ratio 1: 10 Under, 2h is soaked at room temperature with ether, distills to solvent no longer flowing out, be subsequently placed under conditions of 40 DEG C of Extracting temperature 30min is dried in thermostatic drying chamber, so as to obtain Herba Hedyotidis Diffusae extract.
The Aloe extraction solution preparation method is:Aloe is cleaned into peeling, ultrasound wave powder after being cut into the fritter of 1 cun of square, is used It is broken, plus the deionized water immersion 12h of 2-3 times of volume, with 300 mesh silk cover filterings, filtrate is centrifuged into 10min under 2500r/min, Supernatant is Aloe extraction solution.
Cold pressed flax seed oil unsaturated fatty acid content of the present invention is high, skin is had excellent affinity and Penetration, the various fatty acids contained by which are easily absorbed by the skin, and for supplementing the lipid components required for skin, increase skin Cytoactive regeneration capacity, the effects such as with physical skin wound, such as cicatrix is repaired, and can maintain and strengthen Skin Cell film And the normal configuration and function of interstitial;Meanwhile, Semen Lini oil can weaken skin depth to form ventilative water-retaining film in skin surface Layer moisture loss, make skin keep moistening, it is smooth and elastic;Semen Lini oil can play antiinflammatory and anti-proliferative effect, to subtracting Gently there is good effect by UV-induced Erythema and inflammatory reaction, as a kind of rare containing the natural of omega-3 fatty acid Vegetable oil, Semen Lini oil have obvious effect, cold pressed flax seed oil to some skin defect eczema, acne, allergy, chaps etc. For the inflammations such as treatment skin allergy, eczema, chap, infant anthma, skin burn have significantly effect;
Herba Hedyotidis Diffusae extract of the present invention has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, for treatment acne has bright Aobvious effect;
Aloe extraction solution of the present invention has active cell vigor, delay skin aging, convergence pore, nourishes rough skin Effect.
In sum, characteristic of the present invention based on above-mentioned each primary raw material, is extracted with cold pressed flax seed oil, Herba Hedyotidis Diffusae Liquid, Aloe extraction solution are main natural material, have carried out optimization with reference to 18 fatty alcohol, stearic acid, glycerol and deionized water and have matched somebody with somebody Than test, it is determined that optimal proportion of each raw material in component, each component is presented good dose-effect relationship, is directed to finished product ointment Xerosis cutiss, facial physical trauma and acne etc. have good effect, and natural, non-stimulated, moistening effect is good.
Specific embodiment
With reference to embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited to The scope that embodiment is represented.
Embodiment 1
By 8 parts of cold pressed flax seed oils, 2 parts of Herba Hedyotidis Diffusae extracts, 7 part of 18 fatty alcohol, 4 parts of stearic acid, 3 parts of glycerol, 6 Part Aloe extraction solution and 7 parts of deionized waters.
Its preparation method is as follows:
The preparation process of cold pressing Semen Lini is:
1) harvesting of Semen Lini, screening;
2) impurity and shelling are cleared up;
3) shell after Semen Lini be put into air pressure tank squeezing 30min, 2 DEG C of temperature, pressure 20kPa, oil yield are 9%;
4) filter:Semen Lini oil after squeezing is passed through into filter-cloth filtering remove impurity;
5) clarify:Semen Lini oil after filtration is stood, edible vegetable oil is taken and is Semen Lini oil.
The preparation method of Herba Hedyotidis Diffusae extract is:Herba Hedyotidis Diffusae is crushed, under conditions of solid-liquid ratio 1: 10, is used Ether soaks 2h at room temperature, distills to solvent no longer flowing out, be subsequently placed in constant temperature under conditions of 40 DEG C of Extracting temperature 30min is dried in drying baker, so as to obtain Herba Hedyotidis Diffusae extract.
Aloe extraction solution preparation method is:Aloe is cleaned into peeling, after being cut into the fritter of 1 cun of square, ultrasonic grinding is used, Plus the deionized water immersion 12h of 2 times of volumes, with 300 mesh silk cover filterings, filtrate is centrifuged into 10min, supernatant under 2500r/min Liquid is Aloe extraction solution.
All of above raw material is mixed, 50 DEG C is heated to so as to melt, subpackage after stirring.
Embodiment 2
By 5 parts of cold pressed flax seed oils, 3 parts of Herba Hedyotidis Diffusae extracts, 5 part of 18 fatty alcohol, 3 parts of stearic acid, 2 parts of glycerol, 5 Part Aloe extraction solution and 5 parts of deionized waters.
Its preparation method is as follows:
The preparation process of cold pressing Semen Lini is:
1) harvesting of Semen Lini, screening;
2) impurity and shelling are cleared up;
3) shell after Semen Lini be put into air pressure tank squeezing 20min, 0 DEG C of temperature, pressure 10kPa, oil yield are 8%;
4) filter:Semen Lini oil after squeezing is passed through into filter-cloth filtering remove impurity;
5) clarify:Semen Lini oil after filtration is stood, edible vegetable oil is taken and is Semen Lini oil.
The preparation method of Herba Hedyotidis Diffusae extract is:Herba Hedyotidis Diffusae is crushed, under conditions of solid-liquid ratio 1: 10, is used Ether soaks 2h at room temperature, distills to solvent no longer flowing out, be subsequently placed in constant temperature under conditions of 40 DEG C of Extracting temperature 30min is dried in drying baker, so as to obtain Herba Hedyotidis Diffusae extract.
Aloe extraction solution preparation method is:Aloe is cleaned into peeling, after being cut into the fritter of 1 cun of square, ultrasonic grinding is used, Plus the deionized water immersion 12h of 3 times of volumes, with 300 mesh silk cover filterings, filtrate is centrifuged into 10min, supernatant under 2500r/min Liquid is Aloe extraction solution.
All of above raw material is mixed, 50 DEG C is heated to so as to melt, subpackage after stirring.
Embodiment 3
By 10 parts of cold pressed flax seed oils, 5 parts of Herba Hedyotidis Diffusae extracts, 10 part of 18 fatty alcohol, 5 parts of stearic acid, 5 parts it is sweet Oil, 10 parts of Aloe extraction solution and 8 parts of deionized waters.
Its preparation method is as follows:
The preparation process of cold pressing Semen Lini is:
1) harvesting of Semen Lini, screening;
2) impurity and shelling are cleared up;
3) shell after Semen Lini be put into air pressure tank squeezing 40min, 5 DEG C of temperature, pressure 40kPa, oil yield are 8%;
4) filter:Semen Lini oil after squeezing is passed through into filter-cloth filtering remove impurity;
5) clarify:Semen Lini oil after filtration is stood, edible vegetable oil is taken and is Semen Lini oil.
The preparation method of Herba Hedyotidis Diffusae extract is:Herba Hedyotidis Diffusae is crushed, under conditions of solid-liquid ratio 1: 10, is used Ether soaks 2h at room temperature, distills to solvent no longer flowing out, be subsequently placed in constant temperature under conditions of 40 DEG C of Extracting temperature 30min is dried in drying baker, so as to obtain Herba Hedyotidis Diffusae extract.
Aloe extraction solution preparation method is:Aloe is cleaned into peeling, after being cut into the fritter of 1 cun of square, ultrasonic grinding is used, Plus the deionized water immersion 12h of 3 times of volumes, with 300 mesh silk cover filterings, filtrate is centrifuged into 10min, supernatant under 2500r/min Liquid is Aloe extraction solution.
All of above raw material is mixed, 50 DEG C is heated to so as to melt, subpackage after stirring.
The Main Ingredients and Appearance of the compositionss of the present invention washes trouble from natural plant essence without any noxious substance After person's face, by the said goods directly by way of smearing between 18-40 year, face have the symptoms such as cicatrix, small pox, skin sore Men and women try out, user is total up to 100 people, and wherein women is 50 people, and male is 50 people, and the validity period time is 16-32 days.Make It is clearly better with the cicatrix of rear face, small pox, skin sore, cicatrix is thin out, entirely allergic phenomena occurs in process nobody on probation.Show Natural composition short treating period of the present invention, good effect, cure rate is high to prove that its therapeutical effect has a broad spectrum activity, and during treating not It was found that obvious adverse reaction, illustrates that drug safety of the present invention is good.
The several specific application example that the present invention enumerates out is the following is, remaining application example is no longer repeated.
Application Example 1
Miss Zhang, 24 years old, Shenzhen student working on a postgraduate program started dyssecretosises when 23 years old, add and stay up late, eat fry, open Beginning constantly emits small pox in two cheeks, forehead, causes greatly puzzlement.Many product for resolving poxes were tried, effect is all general.2016 2 Begin to use within 25th the product of the present invention moon, second day sufferings degree substantially mitigates, small pox takes off red, starts small pox within the 3rd day and diminishes, Become little red seal after five days, adhere to that being finished 15 days acne prints, pox scars substantially eliminates.
Application Example 2
Mr. Wang, 22 years old, big three were reading student, and face has physically impaired cicatrix existing a year and a half, tried many faces Product is repaired in portion, and effect is all general, and causes the easy allergy of skin, and on March 15th, 2016 begins to use the ointment of the present invention to produce Product, after January, cicatrix is substantially thin out, adheres to that pox scar is substantially eliminated using after three months.
Application Example 3
Mr. Chen, 23 years old, attends Hunan university, and the long pox of cheek 1 year is extruded as Jing commonly uses handss, and face is general red tight Weight, on March 12nd, 2016, three days facial small poxs were mitigated by red point using my company's toothpaste product, and facial small pox is entirely good within seven days.It is hard Hold using after 1 month, the completely no small pox of face, acne print.
Application Example 4
Miss Zhang, 32 years old, forehead had physically impaired cicatrix up to 1 year, and on April 28th, 2016 is produced using my company's ointment Product, after two weeks, cicatrix is substantially thin out, adheres to that pox scar is substantially eliminated using after two months.

Claims (5)

1. it is a kind of with the ointment for repairing cicatrix and treatment acne, it is characterised in that to be made up of following raw materials according by weight:5- 10 parts of cold pressed flax seed oils, 3-5 part Herba Hedyotidis Diffusae extracts, 18 fatty alcohol of 5-10 parts, 3-5 part stearic acid, 2-5 part glycerol, 5-10 parts Aloe extraction solution and 5-8 part deionized waters;Each raw material is mixed, 50 DEG C is heated to so as to melt, is divided after stirring Dress is made.
2. a kind of ointment for treating cicatrix and acne according to claim 1, it is characterised in that the raw material is by weight Meter:8 parts of cold pressed flax seed oils, 2 parts of Herba Hedyotidis Diffusae extracts, 7 part of 18 fatty alcohol, 4 portions of stearic acid, 3 portions of glycerol, 6 portions of Aloes Extracting solution and 7 parts of deionized waters.
3. a kind of ointment for treating cicatrix and acne according to claim 1 and 2, it is characterised in that described cold pressing Caulis et Folium Lini The preparation process of seed is:
1) harvesting of Semen Lini, screening;
2) impurity and shelling are cleared up;
3) Semen Lini after shelling is put into air pressure tank squeezing 20-40min, temperature 0-5 DEG C, pressure 10-40kPa, and oil yield is 8%-10%;
4) filter:Semen Lini oil after squeezing is passed through into filter-cloth filtering remove impurity;
5) clarify:Semen Lini oil after filtration is stood, edible vegetable oil is taken and is Semen Lini oil.
4. a kind of ointment for treating cicatrix and acne according to claim 3, it is characterised in that the Herba Hedyotidis Diffusae extraction The preparation method for taking liquid is:Herba Hedyotidis Diffusae is crushed, and under conditions of solid-liquid ratio 1: 10,2h is soaked at room temperature with ether, Distill to solvent under conditions of 40 DEG C of Extracting temperature no longer flowing out, in being subsequently placed in thermostatic drying chamber, be dried 30min, from And obtain Herba Hedyotidis Diffusae extract.
5. a kind of ointment for treating cicatrix and acne according to claim 4, it is characterised in that the Aloe extraction solution system Preparation Method is:Aloe is cleaned into peeling, ultrasonic grinding, plus the deionized water of 2-3 times of volume after being cut into the fritter of 1 cun of square, is used Filtrate, with 300 mesh silk cover filterings, is centrifuged 10min under 2500r/min by immersion 12h, and supernatant is Aloe extraction solution.
CN201710022035.9A 2017-01-12 2017-01-12 Ointment for treating scars and acne Pending CN106620079A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201710022035.9A CN106620079A (en) 2017-01-12 2017-01-12 Ointment for treating scars and acne

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107536923A (en) * 2017-09-18 2018-01-05 杨平芝 A kind of oldenlandia diffusa antibacterial gel
CN114746077A (en) * 2019-12-16 2022-07-12 高露洁-棕榄公司 Personal care compositions and methods for same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103571657A (en) * 2013-10-24 2014-02-12 朱建华 Natural soap for removing poxes as well as preparation method thereof
CN103599012A (en) * 2013-10-25 2014-02-26 徐花 Whitening and spot removing facial cleanser

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103571657A (en) * 2013-10-24 2014-02-12 朱建华 Natural soap for removing poxes as well as preparation method thereof
CN103599012A (en) * 2013-10-25 2014-02-26 徐花 Whitening and spot removing facial cleanser

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107536923A (en) * 2017-09-18 2018-01-05 杨平芝 A kind of oldenlandia diffusa antibacterial gel
CN114746077A (en) * 2019-12-16 2022-07-12 高露洁-棕榄公司 Personal care compositions and methods for same

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