CN105796457B - A kind of scar anti-acne print lotion and preparation method thereof of dispelling rich in natural extract - Google Patents

A kind of scar anti-acne print lotion and preparation method thereof of dispelling rich in natural extract Download PDF

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CN105796457B
CN105796457B CN201610141353.2A CN201610141353A CN105796457B CN 105796457 B CN105796457 B CN 105796457B CN 201610141353 A CN201610141353 A CN 201610141353A CN 105796457 B CN105796457 B CN 105796457B
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lotion
oil
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CN105796457A (en
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孙淑萍
汪全海
叶萍
汤大娟
金晓灿
姚文静
李悦
郭派派
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Liao Aihua
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Wannan Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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Abstract

The invention discloses a kind of, and the scar anti-acne of dispelling rich in natural extract prints lotion and preparation method thereof, and following substance is contained in the lotion:Aloe, apricot kernel oil, pot marigold oil, Seabuckthorn Oil, house oil, fat of Oromaius norvaehollandeae, glycerine, 1% sodium hyaluronate solution, red sage root extract, larva of a silkworm with batrytis extracting solution, peach kernel extracting solution, centella extracting solution, D panthenols, ML emulsifiers, olive emulsifier, distilled water, silicone oil, sodium alginate, cation guar gum, Compound Resisting microbial inoculum, essence.The present invention is compared with prior art, this breast is in faint yellow, and consistency is suitable, slim and graceful water profit, it is fine and smooth uniform, stretchability is good, fragrant, and active ingredient green is pure natural, Sodium Hyaluronate contained therein has the function of softening, alleviates scar formation, the deep enough skin corium of its active ingredient energy decomposes, the impaired non-functional scar tissue of removing and the various agings of replacement, fibrosis, space is got out to the epithelial cell with regeneration potential.

Description

A kind of scar anti-acne print lotion and preparation method thereof of dispelling rich in natural extract
Technical field
The present invention relates to a kind of lotion more particularly to it is a kind of rich in natural component extract dispel scar anti-acne print lotion and its Preparation method.
Background technology
It is the nature of people to like to be beautiful, everyone is intended to oneself possess the skin of smooth exquisiteness, but always has and accidentally do The acne print that the case where hindering scar after skin or hebetic small pox leave after subsiding, always let us worries endlessly, Some even can generate our Working Life more or less influence with us throughout one's life.
However the lotion of commercial type functions only as the effect of whitening or moisturizing at present, the medicine of some scar anti-acne prints of dispelling Cream function and effect are drug effect type nor very clear, and our scar anti-acne print lotion of dispelling has both nutrition and drug effect, Material therefor is fabulous beauty treatment material, is derived from the Nature, pure natural pollution-free, has taste while dispelling scar anti-acne print Support, whitening, moisturizing effect, for skin provide abundance nutrition, can be used for a long time as the lotion of skin care.
Many manufacturers, in order to allow product to have better white-skinned face function, improve sales volume, open under the driving of interests according to investigations Beginning adds some to the harmful chemical synthesis substance of skin in cosmetics, skin care item, has ignored safely and effectively principle.Its Real, some naturally occurring plant components can be with while improving scar acne print mostly rich in the active constituent for improving skin It slows down aging, such novel product can be effectively relieved the serious stern form in current cosmetics market, meet trend instantly, safe to use It trusts.
Under the promotion of green product theory, natural cosmetics become a kind of fashion, are domestic and international cosmetics research and development from now on Main trend.Chinese herbal medicine raw material resources are abundant, and various in style, easy to use, development prospect is very wide, market On have a great demand to the auxotype containing natural plant active constituent and drug effect type essence lotion, the research and development of such lotion are released Just meet demand instantly.
Invention content
Goal of the invention:The object of the present invention is to provide a kind of new scar anti-acne print breasts of dispelling rich in natural component extract Liquid.
Technical solution:In order to achieve the above-mentioned object of the invention, the technical solution adopted by the present invention is as follows:
A kind of scar anti-acne print lotion of dispelling rich in natural component extract, it is characterised in that:Include following match in lotion The raw material components of ratio:
The red sage root extract is to be prepared by the following method:
It is appropriate to weigh Radix Salviae Miltiorrhizae, impregnates 0.15-1h, is heated to 90-100 DEG C, decocts extraction 3 times, for the first time plus 6-12 times is measured Water, extract 0.5-2h, second plus the 4-10 times of water measured, extract 0.5-1.5h, third time plus 3-8 times measure water, extract 0.5- 1.5h, filters every time, and the volume concentration of merging filtrate, filtrate is filtered to 3-6 times of g/ml of Radix Salviae Miltiorrhizae weight to obtain the final product.
The larva of a silkworm with batrytis extracting solution is to be prepared by the following method:
It is appropriate to weigh the larva of a silkworm with batrytis, is heated to 90-100 DEG C, decocts extraction 3 times, adds the 4-10 times of water measured, extraction for the first time 0.5-2h, second plus the 4-10 times of water measured extract 0.5-1.5h, third time plus the 3-8 times of water measured, extract 0.5-1.5h, often Secondary filtration, merging filtrate, filtrate volume are concentrated into 3-7 times of g/ml of larva of a silkworm with batrytis weight, filter to obtain the final product.
The peach kernel extracting solution is to be prepared by the following method:
It is appropriate to weigh peach kernel coarse powder, is heated to 90-100 DEG C, decocts extraction 2 times, adds the 5-11 times of water measured, extraction for the first time 0.5-2h, second plus the 4-10 times of water measured, extracts 0.5-2h, filters twice, merging filtrate, filtrate volume is concentrated into peach kernel weight 3-6 times of g/ml of amount, is filtered to obtain the final product.
The centella extracting solution is to be prepared by the following method:
It is appropriate to weigh centella, shreds, impregnates 0.15-1h, is heated to 90-100 DEG C, decocts extraction 3 times, adds 8- for the first time The water of 15 times of amounts, extracts 0.5-2h, and second plus the 4-10 times of water measured extract 0.5-1.5h, third time plus the extraction of 3-8 times of water 0.5-1.5h, is filtered every time, and merging filtrate, filtrate volume is concentrated into 4-8 times of g/ml of centella weight, filters to obtain the final product.
The essence be lemon extract, flavoring rose essence, green cucumber essence, peach flavor, lily essence, flavoring pineapple essence, Osmanthus flower fragrance is one or more of.
A kind of preparation method of scar anti-acne print lotion of dispelling rich in natural component extract, includes the following steps:
A) sodium alginate 0.01-0.1g is weighed, water 1-9.9ml is added, is stirred evenly after standing overnight solidifying up to sodium alginate Glue a;
B) cationic guar gum 0.02-0.2g is weighed, water 1-9.8ml is added, is stirred evenly after standing overnight up to cation Guar gum coagulant liquid b;
C) D-panthenol 0.5-3g is weighed, water 0.8-5ml, stirring and dissolving is added to obtain D-panthenol solution c;
D) aloe 0.5-2g, apricot kernel oil 1-3g, pot marigold oil 0.5-3g, Seabuckthorn Oil 0.5-2g, house oil 1-4g, Er are weighed Emu oil 0.1-2g, ML emulsifier 2-4g, olive emulsifier 2-4g are set in small beaker on water-bath, keep 60-90 DEG C of temperature, Heating water bath dissolves, mixing, as oil phase;
E) distilled water 10-25ml is measured in beaker, is set on water-bath, 60-90 DEG C of temperature of holding, heating water bath, as Water phase;
F) it waits for that oil phase melts completely in beaker, the water phase in the beaker of equality of temperature is slowly poured into oil phase, side edged is to same 10-15min is stirred in one direction, until in uniform faint yellow creamy base, is taken out and is cooled to room temperature from water-bath;
G) glycerine 0.5-2g, 1% sodium hyaluronate solution 0.1-2g, D-panthenol solution c, pellet are added after matrix is let cool Join extracting solution 0.5-2g, larva of a silkworm with batrytis extracting solution 0.5-2g, peach kernel extracting solution 0.5-2g, centella extracting solution 0.5-2g, stirring is equal It is even, it is eventually adding silicone oil 0.1-2g, is stirred evenly;
H) it is added in the emulsion bases obtained by and has been swollen complete sodium alginate gel liquid a and cationic guar gum gel Liquid b stirs 5-10min, is uniformly mixed to obtain lotion g;
I) antiseptic 0.5-3ml, essence 0.05-0.3ml are added into lotion g, stirs evenly scar anti-acne print breast of dispelling to obtain the final product Liquid.
The various composition of the present invention is as follows:
Pure oiliness aloe lime set contained by aloe, can give burn, abrade and solarization after lose the skin of moisture content more The moist and nutrient of deep layer, and impaired cell tissue is repaired rapidly, promote cytothesis, and skin is made to get well, has Moisten the direct cosmetic result such as moisturizing, whitening spot-removing, anti-aging, hypo-allergenic.Play simultaneously inhibit skin surface pathogenic microorganisms, Bacterium kills to the harmful acarid of human skin, prevents the breeding of superficial microbes, prevent dermopathic generation.It is suitble to oiliness Skin, balance inhibit sebum secretion, promote wound healing.
Apricot kernel oil is rich in minerals, protein and various vitamins, easily absorbs, is a kind of natural wetting agent, has and grows Support with moisturizing, releive and antianaphylactic effect, be a kind of skin care and the splendid vegetable oil of moisturizing effect, for dry skin Or cause skin discomfort problem extremely helpful because of climate change, cell growth can be promoted, be suitble to dry, sensitive, inflammation and nothing The skin of gloss.It can effectively mitigate skin and itch phenomenon, eliminate redness, dryness and inflammation.It is caused for hyperkinesia Myalgia, can reinforce cell band oxygen function, and dispelling fatigue is accumulated with carbonic acid, has analgesia and abirritant effect, can pierce Swash pituitary gland, thymus gland and the adrenal gland of internal system, promotes cell turnover.
Pot marigold oil possesses superpower healing ability, have the effect of sterilization, convergence wound, can effectively administer inflammation, The skin problems such as dark sore, pore be coarse, while the skin that can calm improve sensibility skin quality, have effects that maintenance scar.Gold Small cup caul-fat can be used for moistening dry lip, and the metabolism of skin, superpower moisturizing effect is promoted to treat dry skin Effect is notable.Pot marigold oil also have excellent anti-oxidation efficacy, injury of the free radical to cell can be eliminated, have Green Tea Extract and The effect of strengthening cell Proliferation promotes cytothesis.
Seabuckthorn Oil can quickly get through microcirculation, Hippophate flavone, carrotene, carotenoid, the phospholipid being rich in Closing object, vitamin E, minerals selenium all has extremely strong anti-oxidant and directly captures Free Radical, and can decompose, be metabolized in blood Rubbish and toxin repair Skin Cell, improve the metabolism of skin.In addition, the Vitamin C content in sea-buckthorn be known as again " fruits and vegetables it King " not only has extremely strong antioxidation, can store in vivo, and have effects that skin whitening.
The Main Components of house oil are oleic acid, linoleic acid and palmitic acid, and wherein oleic acid and linoleic acid total content is 50%.Because House oil is similar with the subcutaneous fat ingredient of people, is conducive to the absorption infiltration of skin, so having good moistening effect, Ke Yiyong Do makeup bottoming and face, body maintenance, in addition also have inhibit color spot, alleviate dermatitis and scald, prevent frostbite, freckle, The skin diseases such as trick bursting by freezing, it is also very effective to face paralysis caused by neuralgia, courbature and hemiplegia.Contain in house oil Some nutrients (vitamin e and leukotrienes) can restore human body health and keep skin tender, and can reinforce that disease is immunized Power and resistance can prevent skin aging, inhibit melanin deposition.
Fat of Oromaius norvaehollandeae is refined by the fat of emu, after penetrating into the skin of people, can accelerate Skin Cell metabolism, It promotes blood circulation, activating cell tissue, promotes skin regeneration, accelerating wound healing, eliminates scytitis, assisting in preventing and treating skin Cancer etc. is known as god's oil by Australia original inhabitant.Fat of Oromaius norvaehollandeae has wound healing, cosmetology and improvement human recycle system The effects that function.The grease of fat of Oromaius norvaehollandeae and human skin is made of very much like aliphatic acid, has very strong skin permeability, Mitigate inflammatory edema, the function of having anti-inflammatory, promote wound healing.As a kind of lubricant, the generation of scar can be inhibited.Fat of Oromaius norvaehollandeae Energy activating cell, promotes the metabolism of cell tissue, the waste in skin is made to drain in time, is not easy precipitation and forms color spot, and The color spot formed in epidermis desalination is set to subside, enhancing Skin Cell regeneration makes fibroblast proliferation, hyaluronic acid increase, Water content increases in skin, and wrinkle of skin is reduced, and the colour of skin is white touched with red.
Radix Salviae Miltiorrhizae effectively can inhibit skin lipid to aoxidize, and improve local microcirculation.Contained tanshinone, danshinolic acid are by pore After absorption, subcutaneous blood circulation can be stimulated, while lipid oxidation being inhibited to react, elimination is led due to poor blood circulation The acne of cause, dark sore, color spot adjust water and oil balance.Water-soluble extract of red sage root has unique pleasant natural faint scent gas, is beautiful Hold the ideal natural material of skincare product, skin can be made adequately to be made moist and nutrition, made one by promoting body surface microcirculation It has rosy cheeks glossy, ecchymosis subsides, and slows down aging.
The larva of a silkworm with batrytis exists《Sheng Nong's herbal classic》In be loaded with:The effect of " go out blackspot, and it is good to make us complexion ".It is carried out by the larva of a silkworm with batrytis When beauty despeckle, outer usage can be used, it is possible to use interior oral administration.The outer used time, the larva of a silkworm with batrytis is smashed, cream is reconciled into honey Shape, smear after face cleaning it is appropriate carry out surface application, have good freckle effect.It, can be with PORIA ALBA, feverfew, rose, silk when for oral administration Melon network etc. enter together pot decoct juice, can whitening, nti-freckle, scar eliminating, treatment facial colour spot, wind-dispelling moisturizing, clinically be used for whitening, dispel Sweat stain, keloid, acne etc..
Peach kernel plays the role of promoting blood circulation, anti-inflammatory, antiallergy, improves microcirculation, and can invigorate blood circulation nti-freckle, and moisturizing is dispelled chapped.《Name doctor It does not record》There is the record of this product " moistening face color ".《Dietetic materia medica》More there is the specific use of " chew one every night and honey be applied to face good " Method.This product is the face spot of blood stasis, acne, brandy nose and skin is dry and astringent, chapped wrinkle, chap are common product.《Imperial physican side》:It " goes Chapped wrinkle pleases skin." peach kernel water decoction and extract have anti-inflammatory, antibacterial, anti-allergic effects.
Centella extract can compact epidermis and corium interconnecting piece, skin can be made to limber up, help promotes in skin corium Collagen is newborn, has the effect for enabling skin compact, also assists in impaired organization healing, inhibits increasing for adipocyte, in advance Anti- hydroderma.
D-panthenol is otherwise known as " provitamin B5" (i.e. vitamin B5Precursor) be moisturizer, softening agent, it is oxidizable, Promote the normal angling of skin, promotes wound healing and skin histology reparation, stimulation cell division to regenerate, have very much to scar healing Effect.
Hyaluronic acid can improve skin growth condition, be provided outside superior for the synthesis of dermal collagen and elastomer The effect of skin-protecting face nursing is played in portion's environment, the supply of reinforced nutrition matter.Studies have shown that hyaluronic acid can prevent in cell The generation of some enzymes reduces the formation of free radical, destroys eucaryotic cell structure preventing free radical, generates lipid peroxidation and causes flesh Body aging etc. plays an important role.Hyaluronic acid has the function of that anti-inflammatory, inhibition germ generates, keeps skin bright and clean;For Cell Proliferation provides suitable place with differentiation, directly facilitates cell growth, differentiation, reconstruction and reparation etc..
In short, this lotion has the function of that oxygen radical can be eliminated, inhibit the generation of color spot, to anti aging effect, can mend Nutrition, the moisture for filling skin needs adjust skin immune function controlling, and enhancing skin resists environmental stimuli, improves skin blood cycle, It boosts metabolism, softens, alleviates the function of scar formation, the deep enough skin corium of active ingredient energy is decomposed, removes and replaced Various agings, fibrosis be damaged non-functional scar tissue, get out space to the epithelial cell with regeneration potential.
Lotion viscosity made by the present invention is suitable, and slim and graceful water profit, fine and smooth uniform, stretchability is good, fragrant.
Specific implementation mode
The present invention is further described with reference to specific embodiment.
The aloe of the present invention, apricot kernel oil, pot marigold oil, Seabuckthorn Oil, house oil, fat of Oromaius norvaehollandeae, ML emulsifiers, olive emulsification Agent, Compound Resisting microbial inoculum are provided by Jiu Heng scientific & trading Co., Ltd.s of Beijing Cigna.
Embodiment 1
The preparation of 1.1 red sage root extracts
Radix Salviae Miltiorrhizae 20g is weighed, 0.5h is impregnated, is heated to 100 DEG C, decocts extraction 3 times, adds the water of 10 times of amounts, extraction for the first time 1h, the water of second plus 8 times amount extract 0.5h, third time plus 8 times of amount water, extract 0.5h, filter every time, merging filtrate, filtrate Volume concentration to 70ml, filter to obtain the final product.
The preparation of 1.2 larva of a silkworm with batrytis extracting solutions
Larva of a silkworm with batrytis 20g is weighed, is heated to 100 DEG C, decocts extraction 3 times, for the first time plus the water of 10 times of amounts, extracts 1h, second Secondary plus 8 times of amounts water, extracts the water of 1h, third time plus 8 times of amounts, extracts 0.5h, filters every time, merging filtrate, filtrate volume is dense It is reduced to 70ml, filters to obtain the final product.
The preparation of 1.3 peach kernel extracting solutions
Peach kernel coarse powder 20g is weighed, is heated to 100 DEG C, extraction 2 times is decocted, adds the water of 10 times of amounts for the first time, extracts 1h, the Secondary plus 8 times of amounts water, extracts 1h, filters twice, merging filtrate, filtrate volume is concentrated into 100ml, filters to obtain the final product.
The preparation of 1.4 centella extracting solutions
Centella 30g is weighed, is shredded, immersion 0.5h is heated to 100 DEG C, decocts extraction 3 times, what first time plus 13 times were measured Water extracts 1h, and the water of second plus 10 times amount extracts 1h, and third time plus 8 times of water extract 0.5h, filters every time, merge filter Liquid, filtrate volume are concentrated into 130ml, filter to obtain the final product.
1.5 dispel scar anti-acne print lotion preparation
A) sodium alginate 0.07g is weighed, water 7.0ml is added, is stirred evenly after standing overnight up to sodium alginate gel liquid a;
B) cation guar gum 0.14g is weighed, water 6.9ml is added, is stirred evenly after standing overnight up to cationic guar gum Coagulant liquid b;
C) D-panthenol 1g is weighed, water 2ml, stirring and dissolving is added to obtain D-panthenol solution c;
D) aloe 1g, apricot kernel oil 1g, pot marigold oil 1g, Seabuckthorn Oil 1g, refined horse oil 1g, fat of Oromaius norvaehollandeae 1g, ML breast are weighed Agent 1.5g, olive emulsifier 2g are set in small beaker on water-bath, keep 80 DEG C of temperature, heating water bath dissolves, mixing;
E) distilled water 20ml is measured in beaker, is set on water-bath, is kept 80 DEG C of temperature, heating water bath;
F) it waits for that oil phase melts completely in beaker, the water phase in the beaker of equality of temperature is slowly poured into oil phase, side edged is to same 15min is stirred in one direction, until in uniform faint yellow cream solid, is taken out and is cooled to room temperature from water-bath;
G) it is molten that glycerine 1g, 1% Sodium Hyaluronate (molecular weight is 20-40 ten thousand) 1g, D-panthenol are added after matrix is let cool Liquid c, red sage root extract 0.8g, larva of a silkworm with batrytis extracting solution 1g, peach kernel extracting solution 1g, centella extracting solution 1.5g, stir evenly successively After the next item down is added, be eventually adding silicone oil 0.7g, stir evenly;
H) breast obtained by, which is added, has been swollen complete sodium alginate gel liquid a and cationic guar gum liquid b, stirs 10min is uniformly mixed to get emulsion g;
I) Compound Resisting microbial inoculum 2ml is added into emulsion g, flavoring rose essence 2 drips (0.1ml), stirs evenly to obtain the final product.
Embodiment 2
The preparation of 2.1 red sage root extracts
Radix Salviae Miltiorrhizae 30g is weighed, 0.5h is impregnated, is heated to 100 DEG C, decocts extraction 3 times, adds the water of 11 times of amounts, extraction for the first time 1h, the water of second plus 9 times amount extract 1h, third time plus 8 times of amount water, extract 0.5h, filter every time, merging filtrate, filtrate Volume concentration is filtered to 120ml to obtain the final product.
The preparation of 2.2 larva of a silkworm with batrytis extracting solutions
Larva of a silkworm with batrytis 30g is weighed, is heated to 100 DEG C, decocts extraction 3 times, for the first time plus the water of 10 times of amounts, extracts 1h, second Secondary plus 8 times of amounts water, extracts the water of 1h, third time plus 8 times of amounts, extracts 0.5h, filters every time, merging filtrate, filtrate volume is dense It is reduced to 90ml, filters to obtain the final product.
The preparation of 2.3 peach kernel extracting solutions
Peach kernel coarse powder 25g is weighed, is heated to 100 DEG C, extraction 2 times is decocted, adds the water of 10 times of amounts for the first time, extracts 1h, the Secondary plus 8 times of amounts water, extracts 1h, filters twice, merging filtrate, filtrate volume is concentrated into 90ml, filters to obtain the final product.
The preparation of 2.4 centella extracting solutions
Centella 40g is weighed, is shredded, immersion 0.5h is heated to 100 DEG C, decocts extraction 3 times, what first time plus 15 times were measured Water extracts 1h, and the water of second plus 9 times amount extracts 1h, and third time plus 8 times of water extract 0.5h, filters every time, merging filtrate, Filtrate volume is concentrated into 170ml, filters to obtain the final product.
2.5 dispel scar anti-acne print lotion preparation
A) sodium alginate 0.08g is weighed, water 7ml is added, is stirred evenly after standing overnight to get sodium alginate gel liquid a;
B) cation guar gum 0.16g is weighed, water 5.8ml is added, is stirred evenly to get cationic guar gum after standing overnight Coagulant liquid b;
C) D-panthenol 1g is weighed, water 2ml, stirring and dissolving is added to obtain D-panthenol solution c;
D) aloe 0.8g, apricot kernel oil 1.2g, pot marigold oil 1.2g, Seabuckthorn Oil 0.8g, house oil 1.1g, fat of Oromaius norvaehollandeae are weighed 0.9g, ML emulsifier 1.9g, olive emulsifier 1.7g are set in small beaker on water-bath, 80 DEG C of temperature of holding, heating water bath, It dissolves, mixing is as oil phase;
E) distilled water 25ml is measured in beaker, is set on water-bath, is kept 80 DEG C of temperature, heating water bath, as water phase;
F) it waits for that oil phase melts completely in beaker, the water phase in the beaker of equality of temperature is slowly poured into oil phase, side edged is to same 15min is stirred in one direction, until in uniform faint yellow cream solid, is taken out and is cooled to room temperature from water-bath;
G) glycerine 2g, 1% Sodium Hyaluronate 0.5g, D-panthenol solution c, red sage root extract are added after matrix is let cool 1g, larva of a silkworm with batrytis extracting solution 1.2g, peach kernel extracting solution 1.4g, centella extracting solution 1.5g, are stirring evenly and then adding into the next item down successively, It is eventually adding silicone oil 1.2g, is stirred evenly;
H) it is added in the breast obtained by and has been swollen complete sodium alginate gel liquid a and cationic guar gum liquid b, stirred 10min is uniformly mixed to obtain lotion g;
I) into lotion g be added Compound Resisting microbial inoculum 2ml, peach flavor 1 drip, stir evenly to get.
Embodiment 3
The preparation of 3.1 red sage root extracts
Radix Salviae Miltiorrhizae 40g is weighed, 0.5h is impregnated, is heated to 100 DEG C, decocts extraction 3 times, adds the water of 12 times of amounts, extraction for the first time 1h, the water of second plus 10 times amount extract 1h, third time plus 8 times of amount water, extract 0.5h, filter every time, merging filtrate, filtrate Volume concentration to 120ml, filter to obtain the final product.
The preparation of 3.2 larva of a silkworm with batrytis extracting solutions
Larva of a silkworm with batrytis 40g is weighed, is heated to 100 DEG C, decocts extraction 3 times, for the first time plus the water of 10 times of amounts, extracts 1h, second Secondary plus 9 times of amounts water, extracts the water of 1h, third time plus 8 times of amounts, extracts 0.5h, filters every time, merging filtrate, filtrate volume is dense It is reduced to 120ml, filters to obtain the final product.
The preparation of 3.3 peach kernel extracting solutions
Peach kernel coarse powder 30g is weighed, is heated to 100 DEG C, extraction 2 times is decocted, adds the water of 10 times of amounts for the first time, extracts 1h, the Secondary plus 8 times of amounts water, extracts 1h, filters twice, merging filtrate, filtrate volume is concentrated into 90ml, filters to obtain the final product.
The preparation of 3.4 centella extracting solutions
Centella 50g is weighed, is shredded, immersion 0.2h is heated to 100 DEG C, decocts extraction 3 times, what first time plus 12 times were measured Water extracts 1h, and the water of second plus 10 times amount extracts 1h, and third time plus 8 times of water extract 0.5h, filters every time, merge filter Liquid, filtrate volume are concentrated into 200ml, filter to obtain the final product.
3.5 dispel scar anti-acne print lotion preparation
A) sodium alginate 0.09g is weighed, water 9ml is added, is stirred evenly after standing overnight up to sodium alginate gel liquid a;
B) cation guar gum 0.18g is weighed, water 7ml is added, is stirred evenly after standing overnight up to sodium alginate gel liquid b;
C) D-panthenol 1.5g is weighed, water 3ml, stirring and dissolving is added to obtain D-panthenol solution c;
D) aloe 2g, apricot kernel oil 1.2g, pot marigold oil 2g, Seabuckthorn Oil 2g, house oil 2g, fat of Oromaius norvaehollandeae 2g, ML emulsification are weighed Agent 2g, olive emulsifier 2g are set in small beaker on water-bath, keep 80 DEG C of temperature, heating water bath dissolves, mixing;
E) distilled water 24ml is measured in beaker, is set on water-bath, is kept 80 DEG C of temperature, heating water bath;
F) it waits for that oil phase melts completely in beaker, the water phase in the beaker of equality of temperature is slowly poured into oil phase, side edged is to same 15min is stirred in one direction, until in uniform faint yellow cream solid, is taken out and is cooled to room temperature from water-bath;
G) glycerine 2g, 1% Sodium Hyaluronate 1.5g, D-panthenol solution c, red sage root extract are added after matrix is let cool 1.5g, larva of a silkworm with batrytis extracting solution 1.5g, peach kernel extracting solution 1.5g, centella extracting solution 1.5g, are stirring evenly and then adding into next successively , it is eventually adding silicone oil 1.2g, is stirred evenly;
H) breast obtained by, which is added, has been swollen complete sodium alginate gel liquid a and cationic guar gum liquid b, stirs 10min is uniformly mixed to obtain lotion g;
I) omnipotent Compound Resisting microbial inoculum 3ml is added into lotion g, lemon extract 6 is dripped, stirred evenly to obtain the final product.
Embodiment 4
The physical and chemical index of embodiment 1,2,3 is as follows:
4.1 character
This lotion is in light yellow, and consistency is suitable, slim and graceful water profit, it is fine and smooth uniformly, stretchability is good, fragrant.
4.2pH value inspections
This product is taken, is measured with pH meter, measures pH value between 5-6.
4.3 caloric test
Lotion is packaged in transparence cosmetic bottle, in 4 DEG C of refrigerator cold-storage observations in one month without lamination.In 55 DEG C Insulating box in for 24 hours, lotion without layering emulsification it is spoiled phenomena such as.
4.4 centrifugal test
Lotion is packaged in 3000r/min in tool plug test tube and centrifuges 20min, no lamination.
4.5 are placed at room temperature for experiment
1,2,3 made lotion of embodiment is placed in bottle for cosmetics, investigation 6 months is stored at room temperature, no lamination is used After feel unchanged, smell is unchanged.
4.6 irritation tests, anaphylaxis experiment
Small white mouse back cuts off hair, smears the lotion that is prepared by embodiment 1,2,3 respectively in cutting plucked position, and do not apply Position is compared, as a result without irritation and allergic reaction.
1 gram of the lotion of 1,2,3 gained of Example is applied in volunteer (15-65 Sui, 120 people) gesture and facial expression, after spending 30 minutes Observation, does not occur rubescent, dermexanthesis, foaming phenomena.
Embodiment 5:
Scar of dispelling anti-acne prints effect experiment
By experiment on probation effect is printed to evaluate the scar anti-acne of dispelling of embodiment 1,2,3.It is produced using embodiment 1,2,3 Lotion with it is commercially available dispel scar anti-acne print ointment carry out contrast experiment.Each 120 of 18-40 Sui men and women is chosen, they are pressed men and women's ratio Example is divided into 4 groups.It is respectively put on the skin at scar with lotion twice sooner or later daily and (can be also applied to skin at no scar), 1 group of use of embodiment By lotion prepared by embodiment 1,2 groups of the embodiment lotions prepared by embodiment 2,3 groups of embodiment is with by the preparation of embodiment 3 Lotion, control group are smeared commercially available scar anti-acne print ointment of dispelling, are used continuously two months.The desalination situation to detect by an unaided eye at scar is come Evaluate scar anti-acne print effect of dispelling.This results are shown in Table 2:
Table 2 dispel scar anti-acne print experimental result
Effectively (people) Slightly effectively (people) (people) in vain Total effective rate (%)
Embodiment 1 22 5 3 90.0
Embodiment 2 24 3 3 90.0
Embodiment 3 23 5 2 93.3
Control group 20 6 4 86.7
Embodiment 6:
The lotion resultant effect is investigated
Following on probation the effect of feeling to evaluate lotion that embodiment 1,2,3 produces.It is scored using opinion poll Method, man, the women for choosing 80 18-40 Sui age brackets are fifty-fifty as object is tried out, and are divided into two groups by male to female ratio, use respectively Lotion prepared by embodiment 1,2,3 puts scar on the skin, at acne print.It uses daily twice, usage time two months.Every using effect is total It is divided into 5 points:Five points are best result, indicate fine, very satisfied;4 points are preferable;3 points are that can receive;3 points or less to be bad, It cannot receive.It is every average below.As a result see 3 tables:
3 resultant effect of table is investigated
In conclusion the made lotion of the present invention has the effect of good desalination scar acne print, moist, moisturizing, after Skin is flexible, pale, and scar, acne print are desalinated gradually even to disappear.

Claims (7)

1. a kind of scar anti-acne print lotion of dispelling rich in natural component extract, it is characterised in that:Include following proportionings in lotion Raw material components:
Aloe 0.5-2g
Apricot kernel oil 1-3g
Pot marigold oil 0.5-3g
Seabuckthorn Oil 0.5-2g
House oil 1-4g
Fat of Oromaius norvaehollandeae 0.1-2g
Glycerine 0.5-2g
1% sodium hyaluronate solution 0.1-2g
D-panthenol 0.5-3g
Red sage root extract 0.5-2g
Larva of a silkworm with batrytis extracting solution 0.5-2g
Peach kernel extracting solution 0.5-2g
Centella extracting solution 0.5-2g
ML emulsifiers 1-4g
Olive emulsifier 1-4g
Silicone oil 0.1-2g
Sodium alginate 0.01-0.1g
Cation guar gum 0.02-0.2g
Distilled water 12.8-49.7ml
Compound Resisting microbial inoculum 0.5-3ml
Essence 0.05-0.3ml.
2. a kind of scar anti-acne print lotion of dispelling rich in natural component extract according to claim 1, which is characterized in that institute The red sage root extract stated is to be prepared by the following method:
It is appropriate to weigh Radix Salviae Miltiorrhizae, impregnates 0.15-1h, is heated to 90-100 DEG C, decocts extraction 3 times, adds the 6-12 times of water measured for the first time, 0.5-2h is extracted, second plus the 4-10 times of water measured extract 0.5-1.5h, and third time plus 3-8 times measure water, extract 0.5-1.5h, Filtration, the volume concentration of merging filtrate, filtrate are filtered to 3-6 times of g/ml of Radix Salviae Miltiorrhizae weight every time to obtain the final product.
3. a kind of scar anti-acne print lotion of dispelling rich in natural component extract according to claim 1, which is characterized in that institute It is to be prepared by the following method to state larva of a silkworm with batrytis extracting solution:
It is appropriate to weigh the larva of a silkworm with batrytis, is heated to 90-100 DEG C, decocts extraction 3 times, adds the 4-10 times of water measured for the first time, extract 0.5- 2h, second plus the 4-10 times of water measured extract 0.5-1.5h, third time plus the 3-8 times of water measured, and extract 0.5-1.5h, filter every time It crosses, merging filtrate, filtrate volume is concentrated into 3-7 times of g/ml of larva of a silkworm with batrytis weight, filters to obtain the final product.
4. a kind of scar anti-acne print lotion of dispelling rich in natural component extract according to claim 1, which is characterized in that institute It is to be prepared by the following method to state peach kernel extracting solution:
It is appropriate to weigh peach kernel coarse powder, is heated to 90-100 DEG C, decocts extraction 2 times, adds the 5-11 times of water measured for the first time, extract 0.5- 2h, second plus the 4-10 times of water measured, extracts 0.5-2h, filters twice, merging filtrate, filtrate volume is concentrated into peach kernel weight 3-6 times of g/ml, is filtered to obtain the final product.
5. a kind of scar anti-acne print lotion of dispelling rich in natural component extract according to claim 1, which is characterized in that institute It is to be prepared by the following method to state centella extracting solution:
It is appropriate to weigh centella, shreds, impregnates 0.15-1h, is heated to 90-100 DEG C, decocts extraction 3 times, adds 8-15 times for the first time The water of amount extracts 0.5-2h, and second plus the 4-10 times of water measured extract 0.5-1.5h, and third time plus 3-8 times of water extract 0.5- 1.5h, is filtered every time, and merging filtrate, filtrate volume is concentrated into 4-8 times of g/ml of centella weight, filters to obtain the final product.
6. a kind of preparation method of scar anti-acne print lotion of dispelling rich in natural component extract according to claim 1, It is characterized in that:The essence be lemon extract, flavoring rose essence, green cucumber essence, peach flavor, lily essence, flavoring pineapple essence, Osmanthus flower fragrance is one or more of.
7. a kind of preparation method of scar anti-acne print lotion of dispelling rich in natural component extract according to claim 1, It is characterized in that the emulsion preparation method includes the following steps:
a)Sodium alginate 0.01-0.1g is weighed, distilled water 1-9.9ml is added, is stirred evenly after standing overnight solidifying up to sodium alginate Glue a;
b)Cation guar gum 0.02-0.2g is weighed, distilled water 1-9.8ml is added, is stirred evenly after standing overnight up to cation Guar gum coagulant liquid b;
c)D-panthenol 0.5-3g is weighed, distilled water 0.8-5ml, stirring and dissolving is added to obtain D-panthenol solution c;
d)Weigh aloe 0.5-2g, apricot kernel oil 1-3g, pot marigold oil 0.5-3g, Seabuckthorn Oil 0.5-2g, house oil 1-4g, fat of Oromaius norvaehollandeae 0.1-2g, ML emulsifier 2-4g, olive emulsifier 2-4g are set in small beaker on water-bath, keep 60-90 DEG C of temperature, water-bath Heating, dissolves, mixing, as oil phase;
e)Distilled water 10-25ml is measured in beaker, is set on water-bath, 60-90 DEG C of temperature, heating water bath, as water phase are kept;
f)It waits for that oil phase melts completely in beaker, the water phase in the beaker of equality of temperature is slowly poured into oil phase, side edged is to same side To stirring 10-15min, until in uniform faint yellow creamy base, takes out and be cooled to room temperature from water-bath;
g)Glycerine 0.5-2g, 1% sodium hyaluronate solution 0.1-2g, D-panthenol solution c, Radix Salviae Miltiorrhizae are added after matrix is let cool to carry Liquid 0.5-2g, larva of a silkworm with batrytis extracting solution 0.5-2g, peach kernel extracting solution 0.5-2g, centella extracting solution 0.5-2g are taken, is stirred evenly, most Silicone oil 0.1-2g is added afterwards, stirs evenly;
h)It is added in the emulsion bases of gained and has been swollen complete sodium alginate gel liquid a and cation guar gum coagulant liquid b, 5-10min is stirred, lotion g is uniformly mixed to obtain;
i)Compound Resisting microbial inoculum 0.5-3ml, essence 0.05-0.3ml are added into lotion g, stirs evenly scar anti-acne print breast of dispelling to obtain the final product Liquid.
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CN106473996B (en) * 2016-12-17 2019-05-28 皖南医学院 A kind of oil-control skin anti-acne that shines repairs facial cleanser and preparation method thereof
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Effective date of registration: 20181229

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Patentee after: Liao Aihua

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Patentee before: Wannan Medical College