CN108888536A - It is a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil and preparation method thereof - Google Patents

It is a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil and preparation method thereof Download PDF

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CN108888536A
CN108888536A CN201811041699.0A CN201811041699A CN108888536A CN 108888536 A CN108888536 A CN 108888536A CN 201811041699 A CN201811041699 A CN 201811041699A CN 108888536 A CN108888536 A CN 108888536A
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郭锦明
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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Abstract

The invention discloses a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil and preparation method thereof.The present inventor is from natural plants, it screens a variety of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect plants essential oil, after compounding by a certain percentage, champignon essence oil of the present invention is made, the champignon essence oil is made of each raw material of following parts by weight:1-3 parts of Rosa Damascana, 1-3 parts of primrose essential oil, 1-3 parts of Chinese ilex essential oil, 0.5-1 parts of cypress essential oil, 0.5-1 parts of clary sage essential oil, 0.5-1 parts of refined jasmine oil, 0.5-1 parts of pot marigold essential oil, 1-3 parts of cinnamon essential oil, 10-20 parts of rose hip oil, 5-15 parts of vitamin E, 10-30 parts and SIMMONDSIA CHINENSIS SEED OIL 10-30 parts of apricot persic oil.Compared to folk prescription essential oil, champignon essence oil effect of the invention is comprehensive, easy to use, melanin can be significantly inhibited to be formed, and there is good moisturizing, anti-wrinkle effect, after use, the smoothness and elasticity that skin can be increased, have broad application prospects and market value.

Description

It is a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil And preparation method thereof
Technical field
It is the present invention relates to a kind of champignon essence oil and preparation method thereof, in particular to a kind of that there is freckle removing and whitening, moisturizing, crease-resistant And the champignon essence oil and preparation method thereof of compact skin effect.The invention belongs to cosmetic technical fields.
Background technique
Acne, spot, obscure, cutis laxa etc. are to perplex the greatest problem of many people seeking beauties.With advancing age, The collagen of skin is gradually lost, and the power of regeneration of Skin Cell is also slowly declining, and consequent is the increasing of wrinkle It is long, the deposition of pigment.And for young man, skin problem is also widely present, sunburn caused by long-term solarization, due to Hair follicle and sebum adenemphraxis, a kind of chronic inflammatory skin that inflammation is caused annoying the people of each age level.
Currently on the market many with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect cosmetics and skincare product, Have it is some come into being by the treatment means of sophisticated equipment, but it is still difficult to reach satisfactory effect.Some beauty Hold skin care item and contain a large amount of chemical synthesis substance, the problem of not can solve skin not only is used for a long time, also will increase skin Burden causes some allergic reactions.Laser nti-freckle, photon delicate skin etc. are in recent years with more technology, although the means exist There can be the effect got instant result in short-term, but effect is difficult to maintain, and medical expense is high, being not suitable for promoting makes With.
Essential oil, English are essential oil, be one kind for being present in plant there is aromatic odor, can be with vapor It distills and the general name of the volatility oily ingredient not miscible with water, mainly passes through steam distillation and squeezing legal system It takes.Plants essential oil is known as the title of " plant hormone ", and the property of many essential oils has important work to human body also like human hormone in fact With.Plants essential oil mainly acts on human body by following approach.
Respiratory system:Plants essential oil molecule stimulates olfactory nerves by breath, and stimulation is reached brain centres by olfactory nerves, Brain generates excited, one side dominating neural, plays the neururgic function of adjusting;On the other hand pass through respiratory system into lung Bubble, enters blood by blood circulation and is delivered directly to each position of whole body.
Nervous system:It is directly entered subcutaneously by affinity interaction, on the one hand plants essential oil molecule stimulates nerve, final to adjust Nervous activity and interior circulation.On the other hand the stable states such as interior environment have been directly changed, have accelerated body fluid activity, so as to improve interior Environment further has the function that adjust entire body and mind.
Metabolic system:Local organization, the living environment of cell are rapidly changed by affinity interaction, adds its metabolism Fastly, comprehensively solve is because of some problems caused by local metabolic obstacle.
Promote exchange:By affinity interaction into subcutaneous tissue, and enter blood and lymph through body fluid exchange, promotes blood And Lymphatic Circulation, accelerate the metabolism of human body.
Directly act on:Essential oil molecule directly kills germ and microorganism.Exempting from for human body can be enhanced into human body essential oil molecule Epidemic disease power.
Currently there are two major classes essential oils, i.e. folk prescription essential oil and compound essential oil.Folk prescription essential oil is exactly a certain plant The plants essential oil of extraction is folk prescription essential oil, generally has this more strong plant scent, and with specific effect and a Property feature.However, folk prescription essential oil effect is single, and using when must be diluted using base oil, therefore using it is upper less It is convenient.Compound essential oil is to reach specific therapeutical for essential oil of more than two kinds and mix, and is mutually coordinated between essential oil and essential oil , some also complement each other each other, heighten the effect of a treatment.Moreover, compared to folk prescription essential oil, when compound essential oil is due to preparing It joined base oil component, therefore can directly have been smeared on the skin, use is more convenient using preceding without dilution.
In view of this, the present invention from natural plants, screens and a variety of has freckle removing and whitening, moisturizing, crease-resistant and compact The plants essential oil of skin effect, and after these plants essential oils are compounded by a certain percentage, being prepared into one kind of the invention has Freckle removing and whitening, moisturizing, the effect of crease-resistant and compact skin champignon essence oil, it is demonstrated experimentally that champignon essence oil of the invention can be shown The formation for inhibiting melanin is write, and there is good moisturizing, anti-wrinkle effect, after use, the brightness, smooth of skin can be increased Therefore degree and elasticity have broad application prospects and market value.
Summary of the invention
The purpose of the present invention is to provide a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon Essential oil and preparation method thereof.
In order to achieve the above object, present invention employs following technological means:
It is of the invention a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil, by following Each raw material of parts by weight forms:1-3 parts of Rosa Damascana, 1-3 parts of primrose essential oil, 1-3 parts of Chinese ilex essential oil, cypress essential oil 0.5-1 Part, 0.5-1 parts of clary sage essential oil, 0.5-1 parts of refined jasmine oil, 0.5-1 parts of pot marigold essential oil, 1-3 parts of cinnamon essential oil, rose 10-20 parts of fruit oil, 5-15 parts of vitamin E, 10-30 parts and SIMMONDSIA CHINENSIS SEED OIL 10-30 parts of apricot persic oil.
Wherein, it is preferred that the champignon essence oil is made of each raw material of following parts by weight:2 parts of Rosa Damascana, oenothera biennis 2 parts of essential oil, 2 parts of Chinese ilex essential oil, 1 part of cypress essential oil, 1 part of clary sage essential oil, 0.5 part of refined jasmine oil, pot marigold essential oil 1 Part, 2 parts of cinnamon essential oil, 15 parts of rose hip oil, 10 parts of vitamin E, 20 parts and 20 parts of SIMMONDSIA CHINENSIS SEED OIL of apricot persic oil.
The present invention from natural plants, screen it is a variety of with freckle removing and whitening, it is moisturizing, crease-resistant and compact skin effect Plants essential oil, and after these plants essential oils are compounded by a certain percentage, be prepared into one kind of the invention with freckle removing and whitening, mend Water, the effect of crease-resistant and compact skin champignon essence oil, wherein:
Rosa Damascana is the natural essential oil extracted using roseleaf as raw material, and there is good beauty and skin care to make With feeding outer Kohakuhi, promotes melanin to decompose within energy, improves dry skin, and recovery skin elasticity allows women to possess white Healthy skin fair-skinned, full of elasticity, is the volatile oil of optimum female health.
Primrose essential oil is in the flower from oenothera biennis, leaf, stem, root or fruit, by steam distillation, extrusion, cold Leaching method or solvent extraction method refine the volatile flavor of extraction.Primrose essential oil can promote fat metabolism, have and moisten skin The effects of skin and weight-reducing.
Chinese ilex essential oil is extracted by the way of distillation from its leaf.Chinese ilex essential oil has the function of antibacterial anti-inflammatory, can improve it is greasy, Unclean and inflammation skin has good effect to tangerine hull constitution and small pox skin.Chinese ilex essential oil contains natural methanol-water Poplar acid, is well-known analgesic.
Cypress essential oil is to be distilled by the Fresh leaves of extraction cypress with cone, colourless or in faint yellow, is distilled out The essential oil come gives out soft wooden faint scent and pleasant amber aroma, can keep isohydria, controls excessive water stream It loses, thus it is quite helpful to adult form skin, adjustment effect is had to hidrosis and oily skin.Moreover, it there are also promote scab Function, be conducive to the healing of wound.
Clary sage essential oil is extracted from Clary Sage plant (Salvia sclarea), can be gentle nervous Nervous system, especially in terms for the treatment of dejected, oppressive, insomnia and long-term uneasiness.In Bergamot Mint Extract and remove face Effect in terms of excess oil especially good.
Refined jasmine oil is to spend middle extraction from jasmine plant (Jasminum officinale), because of the molecule of jasmine It is very small, so can not be extracted in such a way that water distills, but extracted by solvent extraction, so, usually it is referred to as Former smart (Absolute) for jasmine, profession address is " absolute of jasmine ".It has graceful smell to refined jasmine oil, and can releive gloomy feelings Thread inspires enthusiasm, promotes self-confidence, while can nurse genial dry skin, water shortage, excessively oil and sensitive situation, desalination gestation Line and scar increase skin elasticity, skin are allowed to feel more tender.
Pot marigold essential oil is extracted from pot marigold, is had good therapeutic effect for small pox skin, is administered inflammation, disappear Except dark sore, prevent scar from generating coarse with pore.For sensitive skin, it has outstanding calm effect of releiving, and improves sensibility Skin quality repairs the wound that skin is caused by sensitivity, moistens special dry skin.
Cinnamon essential oil is using fresh branches and leaves, stalk and the bark of Lamiaceae plant Chinese cinnamon tree as raw material, using steam distillation Method mentions oil, and obtains through stifling purification.With convergence skin, the slack and undisciplined skin of consolidation, rush says blood circulation, and anti-aging removes skin Skin wart class improves the effect of skin blood circulation.
The present invention is also added into vitamin E on the basis of above-mentioned essential oil, is a kind of very strong antioxidant, can Inhibit the oxidation of fatty acid, reduce the formation of lipofuscin (senile plaque), and protect cells from the damage of free radical, has and delay The effect of aging.In addition, the present invention has selected rose hip oil, oil based on apricot persic oil and SIMMONDSIA CHINENSIS SEED OIL is above-mentioned reconciling On the basis of essential oil, also there is lubrication, nutrition, the effect of moisturizing.
Further, the invention also provides the methods for preparing champignon essence oil of the present invention, including:According to the present invention The parts by weight weigh Rosa Damascana, primrose essential oil, Chinese ilex essential oil, cypress essential oil, clary sage essential oil, jasmine essence Oil, pot marigold essential oil, cinnamon essential oil, rose hip oil, vitamin E, apricot persic oil and SIMMONDSIA CHINENSIS SEED OIL are sufficiently mixed uniformly packing, To obtain the final product.
Further, the invention also provides the champignon essence oil preparation have freckle removing and whitening, moisturizing, it is crease-resistant with And the purposes in the cosmetics of compact skin effect.
Wherein, it is preferred that the cosmetics include cream, lotion, Essence etc..
Further, the present invention also provides the application methods of the champignon essence oil, according to following any method It carries out:
(1) news method is directly inhaled:Champignon essence oil fragrant odour of the invention is heard the intense strain that can releive by inhaling, is made one It feels relief and pleasant;
(2) stacte method:Refer to and champignon essence oil be added drop-wise on aroma diffusing tool, the fragrant atmosphere of essential oil is allowed to be diffused into every nook and cranny, To achieve the effect that sterilization, purification air, skin whitening;
(3) fumigating system:Hot water is added in basin, instills the 1-3 drop champignon essence oil, allows the steam risen to smoke and stroke face Portion first need to remove ornaments and formal dress and wash one's face, and in order to allow steam not scatter, cover entire head with big towel, continue 10-20 minutes, allow champignon The ingredient of essential oil can go deep into skin, to have the function that freckle removing and whitening, moisturizing, crease-resistant and compact skin;
(4) shower method:The champignon essence oil is dripped in water for bathing, immersion body, with reach freckle removing and whitening, moisturizing, The effect of crease-resistant and compact skin;Or
(5) massage:The champignon essence oil is applied to the centre of the palm, can promote essential oil when shortest by massage skin In be absorbed by the skin, and can speed up blood circulation, to have the function that freckle removing and whitening, moisturizing, crease-resistant and compact skin.
Compared to the prior art, the beneficial effects of the invention are as follows:
1, the present inventor is from natural plants, screen it is a variety of with freckle removing and whitening, it is clearing heat and detoxicating and tender skin effect Plants essential oil, and after these plants essential oils are compounded by a certain percentage has been prepared into one kind of the invention with freckle removing and whitening, clear Thermal detoxification and the champignon essence oil of tender skin effect, compared to folk prescription essential oil, champignon essence oil effect of the invention is comprehensive, and uses It is convenient;
2, it is demonstrated experimentally that champignon essence oil of the invention can significantly inhibit the formation of melanin, and there is good benefit Water, anti-wrinkle effect, after use, therefore brightness, smoothness and the elasticity that can increase skin have broad application prospects And market value.
Specific embodiment
The following examples are further illustrations of the invention, it should not be understood as limitation of the present invention.
Embodiment 1 has freckle removing and whitening, moisturizing, the preparation of crease-resistant and compact skin effect champignon essence oil
(1) parts by weight as described below weigh each raw material:
2 parts of Rosa Damascana, 2 parts of primrose essential oil, 2 parts of Chinese ilex essential oil, 1 part of cypress essential oil, 1 part of clary sage essential oil, 0.5 part of refined jasmine oil, 1 part of pot marigold essential oil, 2 parts of cinnamon essential oil, 15 parts of rose hip oil, 10 parts of vitamin E, apricot persic oil 20 Part and 20 parts of SIMMONDSIA CHINENSIS SEED OIL.
(2) by weighed Rosa Damascana, primrose essential oil, Chinese ilex essential oil, cypress essential oil, clary sage essential oil, jasmine Essential oil, pot marigold essential oil, cinnamon essential oil, rose hip oil, vitamin E, apricot persic oil and SIMMONDSIA CHINENSIS SEED OIL are sufficiently mixed uniformly, point Dress to get.
Embodiment 2 has freckle removing and whitening, moisturizing, the preparation of crease-resistant and compact skin effect champignon essence oil
(1) parts by weight as described below weigh each raw material:
1 part of Rosa Damascana, 3 parts of primrose essential oil, 1 part of Chinese ilex essential oil, 1 part of cypress essential oil, clary sage essential oil 0.5 Part, 0.5 part of refined jasmine oil, 0.5 part of pot marigold essential oil, 3 parts of cinnamon essential oil, 20 parts of rose hip oil, 5 parts of vitamin E, apricot peach kernel 30 parts and 10 parts of SIMMONDSIA CHINENSIS SEED OIL of oil.
(2) by weighed Rosa Damascana, primrose essential oil, Chinese ilex essential oil, cypress essential oil, clary sage essential oil, jasmine Essential oil, pot marigold essential oil, cinnamon essential oil, rose hip oil, vitamin E, apricot persic oil and SIMMONDSIA CHINENSIS SEED OIL are sufficiently mixed uniformly, point Dress to get.
Embodiment 3 has freckle removing and whitening, moisturizing, the preparation of crease-resistant and compact skin effect champignon essence oil
(1) parts by weight as described below weigh each raw material:
3 parts of Rosa Damascana, 1 part of primrose essential oil, 3 parts of Chinese ilex essential oil, 0.5 part of cypress essential oil, clary sage essential oil 1 Part, 1 part of refined jasmine oil, 1 part of pot marigold essential oil, 1 part of cinnamon essential oil, 10 parts of rose hip oil, 15 parts of vitamin E, apricot persic oil 10 Part and 30 parts of SIMMONDSIA CHINENSIS SEED OIL.
(2) by weighed Rosa Damascana, primrose essential oil, Chinese ilex essential oil, cypress essential oil, clary sage essential oil, jasmine Essential oil, pot marigold essential oil, cinnamon essential oil, rose hip oil, vitamin E, apricot persic oil and SIMMONDSIA CHINENSIS SEED OIL are sufficiently mixed uniformly, point Dress to get.
1 tyrosinase activity of experimental example and B16 cell Inhibition test
Tyrosinase is currently the only known enzyme in melanin metabolism, it is a kind of metalloenzyme of cupric, thin by melanocyte Born of the same parents' synthesis, very important role has been played during melanocyte generates.Tyrosinase activity increases, and melanocyte generates The just corresponding enhancing of the ability of melanocyte;Otherwise it is corresponding to reduce.If inhibiting the activity of tyrosinase, so that its absorbance changes, Liquid fading extent and enzyme inhibit that quantitative analysis can be carried out with spectrophotometry at stoichiometric relationship.
Given the test agent:
Champignon essence oil composition of the invention is obtained in order to screen, inventor has filtered out two from folk prescription essential oil Ten several suitable skins use, the folk prescription essential oil of fragrant odour, including:Rosa Damascana, Chinese ilex essential oil, clary sage essential oil, Refined jasmine oil, pot marigold essential oil, cinnamon essential oil, chamomile essential oil, flores aurantii essential oil, tea tree ethereal oil, Pogostemon cablin essential, sweet basil essence Oil, Lavender, olibanum essential oil, Rosemary Oil, cypress essential oil, primrose essential oil, Bergamot, Geranium Essential, Honeysuckle essential oil, sandalwood essential oil, eucalyptus quintessence oil and grapefruit essential oil.And according to years of researches experience, by these essential oils It is combined, the combination for therefrom selecting effect best, these combinations include (only listing preferable 7 groups of the test result of effect):
Combination 1:2 parts of Rosa Damascana, 1 part of chamomile essential oil, 2 parts of tea tree ethereal oil, 0.5 part of Pogostemon cablin essential, rosemary essence Oily 0.5 part, 2 parts of primrose essential oil, 0.5 part of sandalwood essential oil;
Combination 2:1 part of flores aurantii essential oil, 2 parts of Basil Essential, 0.5 part of Geranium Essential, 1.5 parts of Lavender, olibanum essence Oily 1 part, 0.5 part of cypress essential oil, 2 parts of honeysuckle essential oil;
Combination 3:2 parts of Rosa Damascana, 2 parts of primrose essential oil, 2 parts of Chinese ilex essential oil, 1 part of cypress essential oil, Clary Sage essence 1 part, 0.5 part of refined jasmine oil, 1 part of pot marigold essential oil, 2 parts of cinnamon essential oil of oil.
Combination 4:2 parts of Rosa Damascana, 2 parts of primrose essential oil, 2 parts of Pogostemon cablin essential, 1 part of cypress essential oil, Geranium Essential 1 part of essential oil, 0.5 part of refined jasmine oil, 1 part of pot marigold essential oil, 2 parts of cinnamon essential oil.
Combination 5:2 parts of Lavender, 2 parts of primrose essential oil, 2 parts of eucalyptus quintessence oil, 1 part of cypress essential oil, happy rat-tail 1 part of careless essential oil, 0.5 part of grapefruit essential oil, 1 part of Chinese ilex essential oil, 2 parts of cinnamon essential oil.
Combination 6:1 part of Rosemary Oil, 0.5 part of Bergamot, 1 part of Pogostemon cablin essential, 1 part of olibanum essential oil, oenothera biennis 0.5 part of essential oil, 1 part of honeysuckle essential oil, 2 parts of flores aurantii essential oil, 1 part of cypress essential oil;
Combination 7:1 part of Rosa Damascana, 1 part of flores aurantii essential oil, 2 parts of Geranium Essential, 1 part of honeysuckle essential oil, primrose essential oil 0.5 part, 0.5 part of cinnamon essential oil, 0.5 part of Bergamot, 0.5 part of grapefruit essential oil.
By weighed essential oil be sufficiently mixed uniformly to get.
Method:
1 tyrosinase activity inhibits test
The Murine melanoma B16 cells of logarithmic growth phase are inoculated in 6 porocyte culture plates, overnight incubation.Respectively plus Enter the given the test agent (essential oil uses emulsifier in advance) that final volume score is 1%, cell controls group is made with untreated fish group, every group 2 multiple holes.It is washed 1 time after culture 48h with PBS, 100 μ L lysates are added in every hole, and scraping collects cell, centrifuging and taking supernatant. 50 μ L cell supernatants to 96 orifice plates are taken, 50 μ L1%L- DOPA solution are added, in 37 DEG C of incubation 1h.M3 plate reader is in 475nm Read absorbance value in place.
Opposite tyrosinase activity=(measurement hole absorbance value-blank control group absorbance value)/(cell controls group extinction Angle value-blank control group absorbance value) × 100%.
2 B16 cell Inhibition tests
16 cell of murine melanoma B of logarithmic growth phase, is inoculated in T25 Tissue Culture Flask, overnight incubation.Respectively The given the test agent that final volume score is 1% is added, using untreated fish group as cell controls group.It is washed 1 time after culture 48h with PBS, 1mL 1mol/L NaOH solution is added, scraping collects cell, is put into 30min in 80 DEG C of water-baths, and take supernatant that 96 orifice plates are added, M3 plate reader reads absorbance value at 475nm.
Relative black cellulose content=(measurement hole absorbance value-blank control group absorbance value)/(cell controls group absorbance Value-blank control group absorbance value) × 100%.
3, result
Essential oil combination inhibits situation as shown in table 1 below intracellular tyrosine enzymatic activity and B16 cell:
1 essential oil of table combines the inhibition to intracellular tyrosine enzymatic activity and B16 cell
As can be seen from Table 1, then in the identical situation of dosage, the essential oil that combination 3 obtains is combined compared to other groups The inhibition to tyrosinase activity and B16 cell in Murine melanoma B16 cells can more significantly be improved.
2 normal individual trial of experimental example tests 1 (whitening effect evaluation and test)
1, experimental subjects and grouping
Choose female volunteers totally 50 for having spot (including freckle, chloasma, sunburn, mercury spot etc.) on the face, age 30-55 Between year.Before smearing champignon essence oil of the invention, glucocorticosteroid hormone, tretinoin and antibiotics, nothing was not used Hyperlipidemia and hepatic and renal function are abnormal, forbid indulging in excessive drinking, avoid sunburst or ultraviolet light excessive radiation.Volunteer is randomly divided into two Group, every group of 25 people:
First group:Evening warm water cleaning skin and after drying, the champignon essence oil for taking 3 drop embodiments 1 to be prepared uniformly applies It smears in face, and suitably massage helps to absorb;
Second group:Evening warm water cleaning skin and after drying, take 3 drops without plant-derived essential oil base oil (i.e. according to The method of embodiment 1, but it is added without plant-derived essential oil) it is uniformly applied to face, and suitably massage helps to absorb.
2, observation statistics
Other drugs or cosmetics are deactivated during use.It is continuous two months on probation, subject face is observed after two months The case where spot, as a result as shown in table 2 below.
Recovery from illness:Face's spot is vanished from sight.
It is effective:Face's spot obviously turns light, becomes smaller, and does not almost see spot and exists.
Effectively:Face's spot, which has, turns light sign, becomes compared to color before using and talks, becomes smaller.
In vain:Spot on the face is without significant change.
2 statistical result of table
Table 2 is the results show that first group and second group of statistical result illustrates there are notable difference in dosage same case Under, wherein the plants essential oil contained has significant freckle effect to freckle, chloasma, sunburn, mercury spot etc..
3 normal individual trial of experimental example tests 2 (evaluation and tests of moisturizing effect)
1, experimental subjects and grouping
It chooses and has dry skin, loose female volunteers totally 50, between 30-55 years old age.Smearing perfume (or spice) of the invention Before smoking essential oil, glucocorticosteroid hormone, tretinoin and antibiotics was not used, no hyperlipidemia and hepatic and renal function are abnormal, prohibit It only indulges in excessive drinking, avoids sunburst or ultraviolet light excessive radiation.Volunteer is randomly divided into two groups, every group of 25 people:
First group:Evening warm water cleaning skin and after drying, the champignon essence oil for taking 3 drop embodiments 1 to be prepared uniformly applies It smears in face, and suitably massage helps to absorb;
Second group:Evening warm water cleaning skin and after drying, take 3 drops without plant-derived essential oil base oil (i.e. according to The method of embodiment 1, but it is added without plant-derived essential oil) it is uniformly applied to face, and suitably massage helps to absorb.
2, observation statistics
Skin water loss TEWL is very important parameter, protective layer of skin to the function of assessment moisture of skin protective layer More intact, the content of moisture will be higher, and the numerical value of skin water loss TEWL is lower.Judgment criteria:Keratoderma water Content, the measurement through severe edema due to hypofunction of the spleen windage and subjective feeling (slight to improve, hence it is evident that improve, no improvement, skin are uncomfortable).
First group of statistical result:1) subjects skin's cuticlar water content significantly rises after 2 weeks, aobvious through severe edema due to hypofunction of the spleen windage Decline is write, 56% subjects subjective experiences skin condition and is significantly improved, and 40% subjects subjective, which experiences skin condition, to be had Slight to improve, 4% subjects subjective's impression is without improvement, phenomena such as no skin is uncomfortable;2) subjects skin's cuticlar water after 4 weeks Content significantly rises, and is remarkably decreased through severe edema due to hypofunction of the spleen windage, and 80% subjects subjective experiences skin condition and is significantly improved, and 20% Subjects subjective experience skin condition and have a slight improvement, no subjects subjective's impression is without improvement, phenomena such as no skin is uncomfortable.
Second group of statistical result:1) the keratoderma water content of subject after 2 weeks, through severe edema due to hypofunction of the spleen windage without significant Variation, 72% subjects subjective, which experiences skin condition, slight improvement, and 28% subjects subjective experiences without improvement, no skin Phenomena such as uncomfortable;2) subjects skin's cuticlar water content after 4 weeks, through severe edema due to hypofunction of the spleen windage without significant changes, 80% it is tested Person's subjective feeling skin condition has a slight improvement, and 20% subjects subjective's impression is without improvement, phenomena such as no skin is uncomfortable.
The skin brightness of volunteer, flatness and elasticity are observed, found compared to second group, first group of will The colour of skin of hope person obviously bleaches, and becomes more flexible, and the skin surface flatness of volunteer obviously makes moderate progress, and has rosy cheeks And it is glossy, scar and pigmentation are greatly reduced, skin is made to restore normal fine and smooth soft and smooth.
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that without departing substantially from of the invention Many other change and modification can be made in the case where spirit and scope.It is, therefore, intended that in the following claims Including belonging to all such changes and modifications in the scope of the invention.

Claims (6)

1. a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil, which is characterized in that described Champignon essence oil is made of each raw material of following parts by weight:1-3 parts of Rosa Damascana, 1-3 parts of primrose essential oil, 1-3 parts of Chinese ilex essential oil, 0.5-1 parts of cypress essential oil, 0.5-1 parts of clary sage essential oil, 0.5-1 parts of refined jasmine oil, 0.5-1 parts of pot marigold essential oil, cortex cinnamomi 1-3 parts of essential oil, 10-20 parts of rose hip oil, 5-15 parts of vitamin E, 10-30 parts and SIMMONDSIA CHINENSIS SEED OIL 10-30 parts of apricot persic oil.
2. champignon essence oil as described in claim 1, which is characterized in that the champignon essence oil by following parts by weight each raw material Composition:2 parts of Rosa Damascana, 2 parts of primrose essential oil, 2 parts of Chinese ilex essential oil, 1 part of cypress essential oil, 1 part of clary sage essential oil, jasmine 0.5 part of essential oil, 1 part of pot marigold essential oil, 2 parts of cinnamon essential oil, 15 parts of rose hip oil, 10 parts of vitamin E, 20 parts of apricot persic oil and 20 parts of SIMMONDSIA CHINENSIS SEED OIL.
3. a kind of method for preparing champignon essence oil of any of claims 1 or 2, which is characterized in that according to claims 1 or 2 institute The parts by weight stated weigh Rosa Damascana, primrose essential oil, Chinese ilex essential oil, cypress essential oil, clary sage essential oil, refined jasmine oil, Pot marigold essential oil, cinnamon essential oil, rose hip oil, vitamin E, apricot persic oil and SIMMONDSIA CHINENSIS SEED OIL are sufficiently mixed uniformly packing, i.e., ?.
4. champignon essence oil described in claim 1 has freckle removing and whitening, moisturizing, crease-resistant and compact skin effect change in preparation Purposes in cosmetic.
5. purposes as claimed in claim 4, which is characterized in that the cosmetics include cream, lotion, Essence.
6. the application method of champignon essence oil of any of claims 1 or 2, which is characterized in that carried out according to following any method:
(1) news method is directly inhaled:Champignon essence oil fragrant odour of the invention hears the intense strain that can releive by inhaling, makes one to feel It is easily and pleasant;
(2) stacte method:Refer to and champignon essence oil is added drop-wise on aroma diffusing tool, allows the fragrant atmosphere of essential oil to be diffused into every nook and cranny, to reach To the effect for sterilizing, purifying air, skin whitening;
(3) fumigating system:It is added hot water in basin, instills champignon essence oil described in 1-3 drop, allow the steam Xun Fu face to rise, First it need to remove ornaments and formal dress and wash one's face, in order to allow steam not scatter, cover entire head with big towel, continue 10-20 minutes, allow champignon essence oil Ingredient can go deep into skin, to have the function that freckle removing and whitening, moisturizing, crease-resistant and compact skin;
(4) shower method:The champignon essence oil is dripped in water for bathing, immersion body, to reach freckle removing and whitening, moisturizing, crease-resistant And the effect of compact skin;Or
(5) massage:The champignon essence oil is applied to the centre of the palm, can promote essential oil within the shortest time by massage skin It is absorbed by the skin, and can speed up blood circulation, to have the function that freckle removing and whitening, moisturizing, crease-resistant and compact skin.
CN201811041699.0A 2018-09-01 2018-09-01 It is a kind of with freckle removing and whitening, moisturizing, crease-resistant and compact skin effect champignon essence oil and preparation method thereof Pending CN108888536A (en)

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CN110772454A (en) * 2019-12-13 2020-02-11 湖北创界生物科技有限公司 Compound essential oil for skin brightening, moisturizing, soothing and anti-aging, and preparation method and application thereof
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CN111773168A (en) * 2020-06-20 2020-10-16 翁小波 Whitening and freckle removing composition and preparation method thereof
CN112237561A (en) * 2020-10-29 2021-01-19 刘鹏媛 Pure natural multifunctional compound essential oil and preparation method thereof
CN112237561B (en) * 2020-10-29 2022-07-22 刘鹏媛 Pure natural multifunctional compound essential oil and preparation method thereof
CN116158999A (en) * 2023-02-28 2023-05-26 江苏更美科技有限公司 Moisturizing anti-wrinkle tightening repair mask and preparation method thereof
CN117503645A (en) * 2023-12-11 2024-02-06 瑞孚生物技术(广州)有限公司 Plant-source anti-allergy soothing oil and preparation method thereof
CN117503645B (en) * 2023-12-11 2024-05-28 瑞孚生物技术(广州)有限公司 Plant-source anti-allergy soothing oil and preparation method thereof

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