CN109125129A - It is a kind of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil and preparation method thereof - Google Patents
It is a kind of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil and preparation method thereof Download PDFInfo
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- CN109125129A CN109125129A CN201811041700.XA CN201811041700A CN109125129A CN 109125129 A CN109125129 A CN 109125129A CN 201811041700 A CN201811041700 A CN 201811041700A CN 109125129 A CN109125129 A CN 109125129A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/20—Fabaceae or Leguminosae [Pea or Legume family], e.g. pea, lentil, soybean, clover, acacia, honey locust, derris or millettia
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/24—Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/36—Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/44—Poaceae or Gramineae [Grass family], e.g. bamboo, lemon grass or citronella grass
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/013—Deodorant compositions containing animal or plant extracts, or vegetable material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention discloses a kind of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil and preparation method thereof.The present inventor is from natural plants, it screens a variety of with freckle removing and whitening, the plants essential oil of clearing heat and detoxicating and tender skin effect, after compounding by a certain percentage, it has been prepared into champignon essence oil of the present invention, the champignon essence oil is made of each raw material of following parts by weight: 1-3 parts of dalbergia wood essential oil, 1-3 parts of lemon grass essential oil, 0.1-1 parts of Lavender, 0.5-1 parts of cypress essential oil, 0.5-1 parts of cinnamon essential oil, 0.1-0.3 parts of Peppermint essential oil, 0.5-1 parts of Geranium Essential, 20-30 parts of Avocado Oil, 5-15 parts of vitamin E, 10-30 parts and SIMMONDSIA CHINENSIS SEED OIL 10-30 parts of wheat-germ oil.Compared to folk prescription essential oil, champignon essence oil effect of the invention is comprehensive and easy to use, the formation of melanin can be significantly inhibited, and there is good bactericidal effect, after use, the smoothness and elasticity that skin can be increased, have broad application prospects and market value.
Description
Technical field
It is the present invention relates to a kind of champignon essence oil and preparation method thereof, in particular to a kind of that there is freckle removing and whitening, clearing heat and detoxicating
And the champignon essence oil and preparation method thereof of tender skin effect.The invention belongs to cosmetic technical fields.
Background technique
Acne, spot, obscure, cutis laxa etc. are to perplex the greatest problem of many people seeking beauties.With advancing age,
The collagen of skin is gradually lost, and the power of regeneration of Skin Cell is also slowly declining, and consequent is the increasing of wrinkle
It is long, the deposition of pigment.And for young man, skin problem is also widely present, sunburn caused by long-term solarization, due to
Hair follicle and sebum adenemphraxis, a kind of chronic inflammatory skin that inflammation is caused annoying the people of each age level.
Currently on the market many with freckle removing and whitening, clearing heat and detoxicating and tender skin effect cosmetics and skincare product, also there is one
It is come into being a bit by the treatment means of sophisticated equipment, but it is still difficult to reach satisfactory effect.Some beauty shields
The problem of skin product contain a large amount of chemical synthesis substance, and long-time service not can solve skin not only, it also will increase the burden of skin
Cause some allergic reactions.Laser nti-freckle, photon delicate skin etc. are in recent years with more technology, although the means are in short-term
There can be the effect got instant result in phase, but effect is difficult to maintain, and medical expense is high, is not suitable for promoting the use of.
Essential oil, English are essential oil, be one kind for being present in plant there is aromatic odor, can be with vapor
It distills and the general name of the volatility oily ingredient not miscible with water, mainly passes through steam distillation and squeezing legal system
It takes.Plants essential oil is known as the title of " plant hormone ", and the property of many essential oils has important work to human body also like human hormone in fact
With.Plants essential oil mainly acts on human body by following approach.
Respiratory system: plants essential oil molecule stimulates olfactory nerves by breath, and stimulation is reached brain centres by olfactory nerves,
Brain generates excited, one side dominating neural, plays the neururgic function of adjusting；On the other hand pass through respiratory system into lung
Bubble, enters blood by blood circulation and is delivered directly to each position of whole body.
Nervous system: being directly entered subcutaneously by affinity interaction, and on the one hand plants essential oil molecule stimulates nerve, final to adjust
Nervous activity and interior circulation.On the other hand the stable states such as interior environment have been directly changed, have accelerated body fluid activity, so as to improve interior
Environment further has the function that adjust entire body and mind.
Metabolic system: rapidly changing local organization, the living environment of cell by affinity interaction, adds its metabolism
Fastly, comprehensively solve is because of some problems caused by local metabolic obstacle.
Promote exchange: by affinity interaction into subcutaneous tissue, and entering blood and lymph through body fluid exchange, promote blood
And Lymphatic Circulation, accelerate the metabolism of human body.
Directly act on: essential oil molecule directly kills germ and microorganism.Exempting from for human body can be enhanced into human body essential oil molecule
Epidemic disease power.
Currently there are two major classes essential oils, i.e. folk prescription essential oil and compound essential oil.Folk prescription essential oil is exactly a certain plant
The plants essential oil of extraction is folk prescription essential oil, generally has this more strong plant scent, and with specific effect and a
Raw feature.However, folk prescription essential oil effect is single, and using when must be diluted using base oil, therefore using it is upper less
It is convenient.Compound essential oil is to reach specific therapeutical for essential oil of more than two kinds and mix, and is mutually coordinated between essential oil and essential oil
, some also complement each other each other, heighten the effect of a treatment.Moreover, compared to folk prescription essential oil, when compound essential oil is due to preparing
It joined base oil component, therefore can directly have been smeared on the skin, use is more convenient using preceding without dilution.
In view of this, the present invention from natural plants, screens and a variety of there is freckle removing and whitening, clearing heat and detoxicating and tender skin to make
Plants essential oil, and after these plants essential oils are compounded by a certain percentage, one kind of the invention has been prepared into nti-freckle beauty
The champignon essence oil of white, clearing heat and detoxicating and tender skin effect, it is demonstrated experimentally that champignon essence oil of the invention can significantly inhibit melanin
Formation, and there is good bactericidal effect, after use, the smoothness and elasticity of skin can be increased, therefore, had wide
Wealthy application prospect and market value.
Summary of the invention
The purpose of the present invention is to provide a kind of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil and
Preparation method.
In order to achieve the above object, present invention employs following technological means:
It is of the invention it is a kind of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil, by following parts by weight
Each raw material composition: 1-3 parts of dalbergia wood essential oil, 1-3 parts of lemon grass essential oil, 0.1-1 parts of Lavender, cypress essential oil 0.5-1
Part, 0.5-1 parts of cinnamon essential oil, 0.1-0.3 parts of Peppermint essential oil, 0.5-1 parts of Geranium Essential, 20-30 parts of Avocado Oil, vitamin E
5-15 parts, 10-30 parts and SIMMONDSIA CHINENSIS SEED OIL 10-30 parts of wheat-germ oil.
Wherein, it is preferred that the champignon essence oil is made of each raw material of following parts by weight: 2 parts of dalbergia wood essential oil, lemonene
2 parts of thatch essential oil, 0.5 part of Lavender, 1 part of cypress essential oil, 1 part of cinnamon essential oil, 0.2 part of Peppermint essential oil, Geranium Essential 1
Part, 25 parts of Avocado Oil, 10 parts of vitamin E, 20 parts and 20 parts of SIMMONDSIA CHINENSIS SEED OIL of wheat-germ oil.
The present invention from natural plants, screen it is a variety of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect plant
Essential oil, and after these plants essential oils are compounded by a certain percentage, one kind of the invention has been prepared into freckle removing and whitening, heat-clearing solution
The champignon essence oil of malicious and tender skin effect, in which:
Dalbergia wood essential oil is the natural medicinal essential oil extracted using dalbergia wood as raw material, and Chinese medicine dalbergia wood is leguminous plant dalbergia wood
The heartwood of wingceltis trunk and root.With the promoting flow of qi and blood circulation, the effect of analgesic hemostatic with effect.
Lemon grass essential oil is the natural medicinal essential oil extracted with lemon grass (lemon grass (Cymbopogon citratus)) for raw material, is suitble to oil
Property and combination, have and adjust fat secretion, reduce the effect of pore, can be used for skin degerming, solve acne problems, it is soft
Soft Rosemary Extract.
Lavender is refined by lavender (Lavender), is had analgesic, anti-melancholy, disinfection, sterilization and is released
The congested function with swelling, there are also blood pressure lowering, expelling parasite, effects that is calm and replying health.
Cypress essential oil is to be distilled by the Fresh leaves of extraction cypress with cone, colourless or in faint yellow, is distilled out
The essential oil come gives out soft wooden faint scent and pleasant amber aroma, can keep isohydria, controls excessive water stream
It loses, thus it is quite helpful to adult form skin, adjustment effect is had to hidrosis and oily skin.Moreover, it there are also promote scab
Function, be conducive to the healing of wound.
Cinnamon essential oil is using fresh branches and leaves, stalk and the bark of Lamiaceae plant Chinese cinnamon tree as raw material, using steam distillation
Method mentions oil, and obtains through stifling purification.With convergence skin, the slack and undisciplined skin of consolidation, rush says blood circulation, and anti-aging removes skin
Skin wart class improves the effect of skin blood circulation.
Peppermint essential oil is the natural medicinal essential oil extracted using peppermint blade as raw material, can improve unclean, obstruction
Skin, refrigerant feeling can shrink capilary, releive and itch, inflammation and burn, can also soft skin, it is black for removing
Head acne and oily skin also great effect.
Geranium Essential is a kind of essential oil being extract using fish pelargonium flower as raw material, and fragrant taste has again and receives
The effect of holding back sterilization can balance the secretion of sebaceous glands.
The present invention is also added into vitamin E on the basis of above-mentioned essential oil, is a kind of very strong antioxidant, can
Inhibit the oxidation of fatty acid, reduce the formation of lipofuscin (senile plaque), and protect cells from the damage of free radical, has and delay
The effect of aging.In addition, the present invention has selected Avocado Oil, oil based on wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL is above-mentioned reconciling
On the basis of essential oil, also there is lubrication, nutrition, the effect of moisturizing.
Further, the invention also provides the methods for preparing champignon essence oil of the present invention, comprising: according to the present invention
The parts by weight weigh dalbergia wood essential oil, lemon grass essential oil, Lavender, cypress essential oil, cinnamon essential oil, Peppermint essential oil,
Geranium Essential, Avocado Oil, vitamin E, wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL, be sufficiently mixed uniformly, packing to get.
Further, the invention also provides the champignon essence oil preparation have freckle removing and whitening, it is clearing heat and detoxicating with
And the purposes in the cosmetics of tender skin effect.
Wherein, it is preferred that the cosmetics include cream, lotion, Essence etc..
Further, the invention also provides the application methods of the champignon essence oil, according to following any method
It carries out:
(1) news method: champignon essence oil fragrant odour of the invention is directly inhaled, the intense strain that can releive is heard by inhaling, makes one
It feels relief and pleasant；
(2) stacte method: referring to and the champignon essence oil be added drop-wise on aroma diffusing tool, and the fragrant atmosphere of essential oil is allowed to be diffused into each angle
It falls, to achieve the purpose that sterilization, purification air, skin whitening；
(3) fumigating system: being added hot water in basin, instills 1-3 drop champignon essence oil, allows the steam Xun Fu face to rise, need
It first removes ornaments and formal dress and washes one's face, in order to allow steam not scatter, cover entire head with big towel, continue 10-20 minutes, allow champignon essence oil
Ingredient can go deep into skin, to have the function that freckle removing and whitening, clearing heat and detoxicating and tender skin；
(4) champignon essence oil shower method: is dripped into the immersion body, to reach freckle removing and whitening, heat-clearing solution in water for bathing
The effect of malicious and tender skin；Or
(5) massage: being applied to the centre of the palm for the champignon essence oil, can promote essential oil when shortest by massage skin
In be absorbed by the skin, and can speed up blood circulation, to have the function that freckle removing and whitening, clearing heat and detoxicating and tender skin.
Compared to the prior art, the beneficial effects of the present invention are:
1, the present inventor is from natural plants, screen it is a variety of with freckle removing and whitening, it is clearing heat and detoxicating and tender skin effect
Plants essential oil, and after these plants essential oils are compounded by a certain percentage has been prepared into one kind of the invention with freckle removing and whitening, clear
Thermal detoxification and the champignon essence oil of tender skin effect, compared to folk prescription essential oil, champignon essence oil effect of the invention is comprehensive, and uses
It is convenient；
2, it is demonstrated experimentally that champignon essence oil of the invention can significantly inhibit the formation of melanin, and there is good kill
Bacterium effect after use, can increase the smoothness and elasticity of skin, therefore have broad application prospects and market value.
Specific embodiment
The following examples are further illustrations of the invention, it should not be understood as limitation of the present invention.
Embodiment 1 has the preparation of freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil
(1) parts by weight as described below weigh each raw material:
2 parts of dalbergia wood essential oil, 2 parts of lemon grass essential oil, 0.5 part of Lavender, 1 part of cypress essential oil, 1 part of cinnamon essential oil,
0.2 part of Peppermint essential oil, 1 part of Geranium Essential, 25 parts of Avocado Oil, 10 parts of vitamin E, 20 parts of wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL
20 parts；
(2) by weighed dalbergia wood essential oil, lemon grass essential oil, Lavender, cypress essential oil, cinnamon essential oil, peppermint essence
Oil, Geranium Essential, Avocado Oil, vitamin E, wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL, be sufficiently mixed uniformly, packing to get.
Embodiment 2 has the preparation of freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil
(1) parts by weight as described below weigh each raw material:
1 part of dalbergia wood essential oil, 3 parts of lemon grass essential oil, 1 part of Lavender, 0.5 part of cypress essential oil, cinnamon essential oil 0.5
Part, 0.3 part of Peppermint essential oil, 0.5 part of Geranium Essential, 20 parts of Avocado Oil, 15 parts of vitamin E, 10 parts of wheat-germ oil and lotus lotus
Bars 30 parts of oil；
(2) by weighed dalbergia wood essential oil, lemon grass essential oil, Lavender, cypress essential oil, cinnamon essential oil, peppermint essence
Oil, Geranium Essential, Avocado Oil, vitamin E, wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL, be sufficiently mixed uniformly, packing to get.
Embodiment 3 has the preparation of freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil
(1) parts by weight as described below weigh each raw material:
3 parts of dalbergia wood essential oil, 1 part of lemon grass essential oil, 0.5 part of Lavender, 1 part of cypress essential oil, cinnamon essential oil 0.5
Part, 0.1 part of Peppermint essential oil, 1 part of Geranium Essential, 30 parts of Avocado Oil, 5 parts of vitamin E, 30 parts of wheat-germ oil and Jojoba
10 parts of oil.
(2) by weighed dalbergia wood essential oil, lemon grass essential oil, Lavender, cypress essential oil, cinnamon essential oil, peppermint essence
Oil, Geranium Essential, Avocado Oil, vitamin E, wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL, be sufficiently mixed uniformly, packing to get.
1 tyrosinase activity of experimental example and B16 cell Inhibition test
Tyrosinase is currently the only known enzyme in melanin metabolism, it is a kind of metalloenzyme of cupric, thin by melanocyte
Born of the same parents' synthesis, very important role has been played during melanocyte generates.Tyrosinase activity increases, and melanocyte generates
The just corresponding enhancing of the ability of melanocyte；Otherwise it is corresponding to reduce.If inhibiting the activity of tyrosinase, so that its absorbance changes,
Liquid fading extent and enzyme inhibit that quantitative analysis can be carried out with spectrophotometry at stoichiometric relationship.
Given the test agent:
Champignon essence oil composition of the invention is obtained in order to screen, inventor has filtered out two from folk prescription essential oil
Ten several suitable skins use, the folk prescription essential oil of fragrant odour, comprising: Rosa Damascana, chamomile essential oil, flores aurantii essential oil, dalbergia wood
Essential oil, tea tree ethereal oil, Pogostemon cablin essential, Basil Essential, lemon grass essential oil, Lavender, angelica essential oil, rosemary essence
Oil, cypress essential oil, primrose essential oil, cinnamon essential oil, Bergamot, Peppermint essential oil, Geranium Essential, honeysuckle essential oil, Du
Loose essential oil, eucalyptus quintessence oil, cus-cus essential oil and grapefruit essential oil.And according to years of researches experience, by these essential oils into
Row combination, the combination for therefrom selecting effect best, these combinations include (only listing preferable 7 groups of the test result of effect):
Combination 1: 2 parts of Rosa Damascana, 1 part of chamomile essential oil, 2 parts of tea tree ethereal oil, 0.5 part of lemon grass essential oil, rosemary
0.5 part of essential oil, 2 parts of primrose essential oil, 0.5 part of Peppermint essential oil；
Combination 2: 1 part of flores aurantii essential oil, 2 parts of dalbergia wood essential oil, 0.5 part of Pogostemon cablin essential, 1.5 parts of Lavender, tanquedate
Oily 1 part, 0.5 part of cypress essential oil, 2 parts of honeysuckle essential oil；
Combination 3: 2 parts of tea tree ethereal oil, 1 part of Basil Essential, 2 parts of cinnamon essential oil, 1 part of needle juniper essential oil, eucalyptus quintessence oil 0.5
Part, 1 part of cus-cus essential oil, 0.5 part of grapefruit essential oil；
Combination 4: 2 parts of Rosa Damascana, 1 part of Pogostemon cablin essential, 0.5 part of Basil Essential, 1 part of Bergamot, Peppermint essential oil
0.5 part, 1 part of eucalyptus quintessence oil, 1 part of cus-cus essential oil；
Combination 5: 2 parts of dalbergia wood essential oil, 2 parts of lemon grass essential oil, 0.5 part of Lavender, 1 part of cypress essential oil, cinnamon spirit
1 part, 0.2 part of Peppermint essential oil, 1 part of Geranium Essential of oil；
Combination 6: 1 part of chamomile essential oil, 0.5 part of dalbergia wood essential oil, 1 part of Pogostemon cablin essential, 1 part of needle juniper essential oil, vetivert
Oily 0.5 part, 1 part of honeysuckle essential oil, 2 parts of Bergamot；
Combination 7: 1 part of Rosa Damascana, 1 part of flores aurantii essential oil, 2 parts of Geranium Essential, 1 part of honeysuckle essential oil, primrose essential oil
0.5 part, 0.5 part of cinnamon essential oil, 0.5 part of Peppermint essential oil, 0.5 part of cus-cus essential oil.
By weighed essential oil be sufficiently mixed uniformly to get.
Method:
1 tyrosinase activity inhibits test
The Murine melanoma B16 cells of logarithmic growth phase are inoculated in 6 porocyte culture plates, overnight incubation.Respectively plus
Enter the given the test agent (essential oil uses emulsifier in advance) that final volume score is 1%, cell controls group is made with untreated fish group, every group
2 multiple holes.It is washed 1 time after culture 48h with PBS, 100 μ L lysates are added in every hole, and scraping collects cell, centrifuging and taking supernatant.
50 μ L cell supernatants to 96 orifice plates are taken, 50 μ L 1%L- DOPA solution are added, in 37 DEG C of incubation 1h.M3 plate reader in
Absorbance value is read at 475nm.
Opposite tyrosinase activity=(measurement hole absorbance value-blank control group absorbance value)/(cell controls group extinction
Angle value-blank control group absorbance value) × 100%.
2 B16 cell Inhibition tests
The Murine melanoma B16 cells of logarithmic growth phase are inoculated in T25 Tissue Culture Flask, overnight incubation.Respectively plus
Enter the given the test agent that final volume score is 1%, using untreated fish group as cell controls group.It is washed 1 time, is added with PBS after culture 48h
Enter 1mL 1mol/L NaOH solution, scraping collects cell, is put into 30min in 80 DEG C of water-baths, takes supernatant that 96 orifice plates, M3 is added
Plate reader reads absorbance value at 475nm.
Relative black cellulose content=(measurement hole absorbance value-blank control group absorbance value)/(cell controls group absorbance
Value-blank control group absorbance value) × 100%.
3, result
Essential oil combination inhibits situation as shown in table 1 below intracellular tyrosine enzymatic activity and B16 cell:
1 essential oil of table combines the inhibition to intracellular tyrosine enzymatic activity and B16 cell
| Grouping | Tyrosinase activity (%) | B16 cell (%) |
| Combination 1 | 75.21±1.25 | 83.52±2.32 |
| Combination 2 | 70.49±7.48 | 80.42±5.35 |
| Combination 3 | 96.56±4.12 | 97.66±2.35 |
| Combination 4 | 79.34±3.56 | 84.53±2.46 |
| Combination 5 | 96.76±2.54 | 98.12±3.76 |
| Combination 6 | 67.89±4.25 | 75.78±2.53 |
| Combination 7 | 82.34±4.89 | 85.45±5.76 |
As can be seen from Table 1, then in the identical situation of dosage, the essential oil combination that combination 3 and combination 5 obtain is compared
It can more significantly improve in other groups to the tyrosinase activity and B16 cell in Murine melanoma B16 cells
Inhibit.
The fungistatic effect of 2 essential oil of experimental example combination
1, tested strain
Propionibacterium acnes freeze-drying lactobacillus ATCC 11827, staphylococcus aureus ATCC6538.
2, for trying culture medium
10% sheep blood and 2% agar is added in improvement GAM broth bouillon, dissolves by heating, 115 DEG C of high pressure sterilization 15min,
It is poured in plate culture dish, the recovery plate and slant medium of freeze-dried vaccine is used as with this.
3, the preparation of bacteria suspension
It is seeded in plate using plate streak by bacterial strain is lyophilized, after 37 DEG C of Anaerobic culturel 72h, what picking was individually grown
Bacterium colony is seeded to improvement GAM broth bouillon, continues culture for 24 hours, as bacteria suspension.
4, subject material:
Essential oil combines 1-7, with experimental example 1.
5, bacteriostatic experiment specific steps:
Using disc diffusion method, is carried out under aseptic condition, filter paper is broken into the circular filter paper of diameter 6mm with punch
Piece, is placed in clean clean small beaker, after 115 DEG C of hot air sterilization 20min, is respectively put into the sample for the experimental group I-VIII that sterilized
It is sufficiently impregnated in liquid, 8 filter papers is put into every kind of sample liquid.Melt prepared for examination culture medium, pours into training respectively
It supports in ware, 115 DEG C of sterilizing 20min, after solidification to be cooled, it is uniform in being coated on plate to draw 0.1ml bacteria suspension.Use aseptic nipper
Clamping the diameter impregnated in proposing sample liquid respectively is 6mm circular filter paper piece, is attached on plate containing bacterium, in each plate etc.
Each culture dish is placed in plate in 37 DEG C of constant incubators and is inverted culture for 24 hours, measures the size of antibacterial circle diameter by distance patch 4,
If 3 repetitions, take its average value.The results are shown in Table 2.
The fungistatic effect of the different sample liquids of table 2 compares
From table 2 it can be seen that combination 5 has higher inhibition Cuo compared to other combinations in the case where same dosage
The activity of sore Propionibacterium and staphylococcus aureus.
3 normal individual trial of experimental example experiment 1
1, experimental subjects and grouping
Choose female volunteers totally 50 for having spot (including freckle, chloasma, sunburn, mercury spot etc.) on the face, age 30-55
Between year.Before smearing champignon essence oil of the invention, glucocorticosteroid hormone, tretinoin and antibiotics, nothing was not used
Hyperlipidemia and hepatic and renal function are abnormal, forbid indulging in excessive drinking, avoid sunburst or ultraviolet light excessive radiation.Volunteer is randomly divided into two
Group, every group of 25 people:
First group: evening warm water cleaning skin and after drying, the champignon essence oil for taking 3 drop embodiments 1 to be prepared uniformly applies
It smears in face, and suitably massage helps to absorb；
Second group: evening warm water cleaning skin and after drying, take 3 drops without plant-derived essential oil base oil (i.e. according to
The method of embodiment 1, but it is added without plant-derived essential oil) it is uniformly applied to face, and suitably massage helps to absorb.
2, observation statistics
Other drugs or cosmetics are deactivated during use.It is continuous two months on probation, subject face is observed after two months
The case where spot, as a result as shown in table 3 below.
Recovery from illness: face's spot is vanished from sight.
Effective: face's spot obviously turns light, becomes smaller, and does not almost see spot and exists.
Effective: face's spot, which has, turns light sign, becomes compared to color before using and talks, becomes smaller.
Invalid: spot on the face is without significant change.
3 statistical result of table
Table 3 is the results show that first group and second group of statistical result illustrates there are notable difference in dosage same case
Under, wherein the plants essential oil contained has significant freckle effect to freckle, chloasma, sunburn, mercury spot etc..
4 normal individual trial of experimental example experiment 2
1, experimental subjects and grouping
Choose it is light, moderate face acne vulgaris volunteer totally 50, male, female are fifty-fifty；Age 20-35 years old.It makes up smearing
2 weeks before product, glucocorticosteroid hormone, tretinoin and antibiotics was not used, no hyperlipidemia and hepatic and renal function are abnormal, prohibit
It only indulges in excessive drinking, avoids sunburst or ultraviolet light excessive radiation.Volunteer is randomly divided into two groups, every group of 25 people:
First group: evening warm water cleaning skin and after drying, the champignon essence oil for taking 3 drop embodiments 1 to be prepared uniformly applies
It smears in face, and suitably massage helps to absorb；
Second group: evening warm water cleaning skin and after drying, take 3 drops without plant-derived essential oil base oil (i.e. according to
The method of embodiment 1, but it is added without plant-derived essential oil) it is uniformly applied to face, and suitably massage helps to absorb.
2, observation statistics
Other drugs or cosmetics are deactivated during use.Continuous on probation 28 days, and require the 14th day (D14) of test and the
(D28) is paid a return visit within 28 days.Evaluation content include the Whiteheads of volunteer's left and right face, blackhead, papule, tumour tubercle with
And the acne of 5 ranks of warts carries out the label and number statistical of number, while skin brightness to volunteer and acne
Healing state is observed.As a result as shown in table 3 below:
4 statistical result of table
Table 4 is the results show that first group and second group of statistical result there are notable difference, illustrates the plant wherein contained essence
Oil has the inhibitory effect of highly significant to acne.It, can compared to the base oil without plants essential oil under dosage same case
Significantly improve the effect for inhibiting acne.
The healing state of skin brightness and acne to volunteer is observed, and is found compared to second group, first group
The colour of skin of volunteer obviously bleaches, and becomes more flexible, and the skin surface flatness of volunteer obviously makes moderate progress, red complexion
Moisten and glossy, greatly reduce scar and pigmentation, skin is made to restore normal fine and smooth soft and smooth.
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that without departing substantially from of the invention
Many other change and modification can be made in the case where spirit and scope.It is, therefore, intended that in the following claims
Including belonging to all such changes and modifications in the scope of the invention.
Claims (6)
1. it is a kind of with freckle removing and whitening, clearing heat and detoxicating and tender skin effect champignon essence oil, which is characterized in that the champignon essence
Oil is made of each raw material of following parts by weight: 1-3 parts of dalbergia wood essential oil, 1-3 parts of lemon grass essential oil, and 0.1-1 parts of Lavender,
0.5-1 parts of cypress essential oil, 0.5-1 parts of cinnamon essential oil, 0.1-0.3 parts of Peppermint essential oil, 0.5-1 parts of Geranium Essential, Avocado Oil 20-
30 parts, 5-15 parts of vitamin E, 10-30 parts and SIMMONDSIA CHINENSIS SEED OIL 10-30 parts of wheat-germ oil.
2. champignon essence oil as described in claim 1, which is characterized in that the champignon essence oil by following parts by weight each raw material
Composition: 2 parts of dalbergia wood essential oil, 2 parts of lemon grass essential oil, 0.5 part of Lavender, 1 part of cypress essential oil, 1 part of cinnamon essential oil, peppermint
0.2 part of essential oil, 1 part of Geranium Essential, 25 parts of Avocado Oil, 10 parts of vitamin E, 20 parts and 20 parts of SIMMONDSIA CHINENSIS SEED OIL of wheat-germ oil.
3. a kind of method for preparing champignon essence oil of any of claims 1 or 2, which is characterized in that according to claims 1 or 2 institute
The parts by weight stated weigh dalbergia wood essential oil, lemon grass essential oil, Lavender, cypress essential oil, cinnamon essential oil, Peppermint essential oil, day
Zhu Kui essential oil, Avocado Oil, vitamin E, wheat-germ oil and SIMMONDSIA CHINENSIS SEED OIL, be sufficiently mixed uniformly, packing to get.
4. champignon essence oil described in claim 1 has freckle removing and whitening, clearing heat and detoxicating and tender skin effect cosmetics in preparation
In purposes.
5. purposes as claimed in claim 4, which is characterized in that the cosmetics include cream, lotion, Essence.
6. the application method of champignon essence oil of any of claims 1 or 2, which is characterized in that carried out according to following any method:
(1) news method: champignon essence oil fragrant odour of the invention is directly inhaled, the intense strain that can releive is heard by inhaling, makes one to feel
It is easily and pleasant；
(2) stacte method: referring to and the champignon essence oil be added drop-wise on aroma diffusing tool, and the fragrant atmosphere of essential oil is allowed to be diffused into every nook and cranny,
To achieve the purpose that sterilization, purification air, skin whitening；
(3) fumigating system: being added hot water in basin, instills 1-3 drop champignon essence oil, allows the steam Xun Fu face to rise, need to first unload
Adornment simultaneously washes one's face, and in order to allow steam not scatter, covers entire head with big towel, continues 10-20 minutes, allows the ingredient of champignon essence oil
It can go deep into skin, to have the function that freckle removing and whitening, clearing heat and detoxicating and tender skin；
(4) shower method: the champignon essence oil being dripped in water for bathing, immersion body, with reach freckle removing and whitening, it is clearing heat and detoxicating with
And the effect of tender skin；Or
(5) massage: being applied to the centre of the palm for the champignon essence oil, can promote essential oil within the shortest time by massage skin
It is absorbed by the skin, and can speed up blood circulation, to have the function that freckle removing and whitening, clearing heat and detoxicating and tender skin.
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| CN110772454A (en) * | 2019-12-13 | 2020-02-11 | 湖北创界生物科技有限公司 | Compound essential oil for skin brightening, moisturizing, soothing and anti-aging, and preparation method and application thereof |
| CN111388358A (en) * | 2020-05-13 | 2020-07-10 | 黄敏 | Plant essential oil composition with mite-killing and acne-removing effects, and preparation and application thereof |
| CN113332381A (en) * | 2021-06-23 | 2021-09-03 | 夏艳 | Traditional Chinese medicine incense for whitening skin and removing freckles and preparation method thereof |
| CN115487084A (en) * | 2022-08-26 | 2022-12-20 | 陕西畅想制药有限公司 | Compound essential oil containing ferulic acid derivative for removing acne, whitening skin and resisting oxidation, preparation method thereof and composition for removing acne, whitening skin and resisting oxidation |
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| CN110090193A (en) * | 2019-05-14 | 2019-08-06 | 东方爱堡(北京)母婴健康科技有限公司 | A kind of anti-acne moisturizing essence and preparation method thereof with fat reducing |
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| CN110772454A (en) * | 2019-12-13 | 2020-02-11 | 湖北创界生物科技有限公司 | Compound essential oil for skin brightening, moisturizing, soothing and anti-aging, and preparation method and application thereof |
| CN110772454B (en) * | 2019-12-13 | 2023-07-21 | 湖北创界生物科技有限公司 | Skin-brightening, moisturizing, soothing and anti-aging compound essential oil, and preparation method and application thereof |
| CN111388358A (en) * | 2020-05-13 | 2020-07-10 | 黄敏 | Plant essential oil composition with mite-killing and acne-removing effects, and preparation and application thereof |
| CN113332381A (en) * | 2021-06-23 | 2021-09-03 | 夏艳 | Traditional Chinese medicine incense for whitening skin and removing freckles and preparation method thereof |
| CN115487084A (en) * | 2022-08-26 | 2022-12-20 | 陕西畅想制药有限公司 | Compound essential oil containing ferulic acid derivative for removing acne, whitening skin and resisting oxidation, preparation method thereof and composition for removing acne, whitening skin and resisting oxidation |
| CN115487084B (en) * | 2022-08-26 | 2023-11-21 | 陕西畅想制药有限公司 | Acne-removing, whitening and antioxidant compound essential oil containing ferulic acid derivative, preparation method and acne-removing, whitening and antioxidant composition |
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