KR101434449B1 - Natural Fragrance Composition Displaying Anti-tress Using an Essential Oil Extract of Torreya nucifera Leaf - Google Patents

Abstract

The present invention discloses a functional natural perfume composition using an essential oil extract of Visa tree leaf. Specifically, the present invention discloses a functional natural perfume composition using an essential oil extract of Visa tree having antistress activity as an active ingredient.

Description

[0001] The present invention relates to an anti-stress natural herbal composition comprising an essential oil extract of a visa tree leaf,

The present invention relates to an anti-stress natural herbal composition using an essential oil extract of Visa tree leaf.

Aroma is a horse that contains the physical components and aroma of essential oil extracted from plants such as herbs and herbs. Aromatherapy is natural or complementary therapy using aroma.

Aromatic essential oils stimulate the limbic system through the olfactory sense, and the limbic system can relax the sympathetic nervous system and the stress response by influencing the autonomic nervous system and the stress neuroendocrine system through the hypothalamus. Therefore, aroma therapy has been used as a complementary therapy for stress, mental and physical relaxation and mood swings.

The plant essential oils used in aroma therapy can be applied to the skin or massages the skin to provide a sufficient moisture lipid balance. Massage with plant essential oils can be used to relax muscles, metabolism, and blood circulation. There may be a chemical or pharmacological effect of the absorbed perfume itself.

In addition, plant essential oils have common features such as preservation, sterilization, and analgesia in addition to fragrance, and the essential oil components absorbed in the capillary blood vessels are able to act as antibiotics and sedatives by circulating in the bloodstream. Aroma therapy combined with massage therapy by hand, in addition to the action of the olfactory central nervous system through the inhalation of fragrance, will enhance the absorption of essential oils through the skin and the mental and physical effects of the massage itself.

On the other hand, as the economy develops and the standard of living improves, the demand for the appearance is increasing, and the demand for products such as cosmetics, hair cleaners, bath salts, deodorants and perfumes is also increasing. These products add a certain amount of flavor, and most products use chemical synthetic flavors. However, chemical synthetic fragrances do not give a lasting affinity to the user, and additives used for long lasting fragrance may cause side effects such as allergic reactions. Therefore, it is still necessary to continuously develop natural fragrance using plant essential oil.

Visa (榧子, Torreya nucifera ) is an evergreen coniferous tree belonging to Taxaceae and is distributed worldwide only in our country and Japan. Visa trees are used for edible, ornamental, industrial, and medicinal purposes. Seeds are eaten or squeezed out of oil.

In the oriental medicine and the private sector, the fruits are used for medicines such as insect repellence, hair growth, dry land, landscape, and intramuscular injection, and timber is used for building materials, machinery materials, ship lumber, etc. (Kim Taejung, 1996; Jang Changsoo, Asian herbal medicine book, p23, Book publication Kyungwon, 1997).

Separation and reported components of leaves and seeds of visa trees include sesquiterpenoids (Sakai, T. et al., Bull. Chem. Soc. Japan, 38: 381, 1965), labdane series And abietane-family diterpenoids (Sayama, Y. et al, Agric. Bio. Chem., 35: 1068, 1971; Harrison, L. and Asakawa, Y., Phytochemistry, 26: 1211, 1987 ), Flavonoids (Kariyone, T. and Sawaka, T., Ykugaku Zasshi, 78: 1010, 1958).

The present invention discloses the use of essential oil extract of Vijayama leaf having functionalities such as antistress activity as a flavoring agent.

It is an object of the present invention to provide a functional perfume composition using non-essential oil essential oil extract.

Other objects and specific objects of the present invention will be described below.

The present invention increases the ratio of alpha wave used as an index for relaxation and stabilization in the EEG analysis when the essential oil extract of Viza leaves is inhaled and the state trait anxiety inventory (STAI-KYZ I) , And perfume sensory evaluation was completed by confirming that the fragrance is represented by an evaluation that the fragrance is natural and intense. The STAI-KYZ (State Trait Anxiety Inventory) was developed to discriminate the concepts of stress and anxiety and to distinguish individual anxieties of trait anxiety, which is a temporary emotional state, and relatively stable personality trait, The results of this study are summarized as follows. First, the results of this study are as follows. First, the results of this study are as follows.

The present invention is completed on the basis of these experimental results. In one aspect, the present invention can be grasped as an anti-stress perfume composition comprising an essential oil extract of Visa tree leaf as an active ingredient.

In the present specification, "extract of essential oil of visa tree leaf" refers to an extract of oil phase obtained by condensing a perfume ingredient from a visa tree leaf to be extracted. The preparation of the essential oil extract may be carried out by a method known in the art such as steam distillation, solvent extraction using a volatile solvent (benzene, hexane, etc.), leaching (scratching the extraction target to collect leached fluid), supercritical extraction .

In the present specification, "anti-stress" means restoration of mental fatigue, specifically, relaxation of tension, relief of anxiety, and / or improvement of concentration.

The perfume composition of the present invention may contain 0.00001% to 10% by weight, preferably 0.00001% to 10% by weight, based on the total weight of the perfume composition, depending on the product form of the perfume composition of the present invention, By weight to 1.0% by weight, and more preferably 0.00001% by weight to 0.5% by weight.

The product form in which the perfume composition is embodied includes soaps, cosmetics, bath salts, and the like, and specifically includes a body lotion, a shampoo, a hair conditioner, a hair conditioner, a hair treatment agent, a perspiration inhibitor, a skin lotion, a skin cream, a deodorant, Spray, or fumigant), lipstick, lip balm, bath salts, and the like.

These products may contain various additives such as blood circulation promoters, antiinflammatory agents, moisturizers, astringents, inorganic salts, organic salts, oily components, surfactants, herbal medicines, coloring matters, fragrances, sulfur, sinter deposits, .

In particular, the perfume composition of the present invention is generally used as an external preparation for skin of cosmetic formulations such as a makeup product, a skin lotion, and a skin cream. In this case, the perfume composition may contain components commonly used in these cosmetic formulations.

Examples of such components include inorganic powders and organic powders (e.g., homopolymers, copolymers, and resins). Particularly, talc, sericite, mica, kaolin, silicone resin, nylon and the like are preferable as such powder because of their excellent feel. The average particle size of these powders is preferably from 0.1 to 15 탆, particularly from 1 to 10 탆. When considering the feeling of use, the powder may be added in an amount of 1 to 60% by weight, particularly 5 to 25% by weight, based on the total weight of the composition for external application for skin.

The external preparation for skin of the present invention may also contain an oily substance. Preferred oily substances from the viewpoint of feeling in use are avocado oil, sucky oil, turtle oil, corn oil, olive oil, wheat germ oil, soybean oil, jojoba oil, peanut oil, cocoa butter, lanolin, liquid paraffin,

Squalane, squalene, petrolatum, cholesteryl ester, and silicone oil. The preferred content range of such an oily substance is 0.1 to 20% by weight, particularly 1 to 10% by weight.

In addition, the external preparation for skin of the present invention may contain an alcohol. Preferred alcohols include ethyl alcohol, propylene glycol, 1,3-butylene glycol, glycerol, sorbitol and the like. The alcohols can be used alone or as a mixture of two or more. In terms of feeling on use, the alcohol may be added in an amount of 0.1 to 30% by weight, particularly 1 to 20% by weight, based on the total weight of the composition for external application for skin of the present invention.

The composition for external application for skin of the present invention may further contain other functional substances such as a moisturizing agent, an anti-inflammatory agent, a whitening agent, an ultraviolet absorber, a bactericide, a limiting agent and the like.

The composition for external application for skin of the present invention may be manufactured in any form and may be in the form of, for example, a lotion, an emulsion, a cream, a powder, a poultice, a pack, a massage, a gel, a paste and a spray.

In particular, the perfume composition of the present invention may preferably be used by being mixed with a bath agent in view of having an anti-stress activity of the essential oil extract of Visa tree leaf which is an effective ingredient of the perfume composition of the present invention. In this case, By weight, preferably 0.00001 to 1% by weight, more preferably 0.0001 to 0.1% by weight.

When the perfume composition of the present invention is incorporated in a bath agent, the bath agent may be added to bath water at a concentration of 0.015 to 15 ppm.

The bath agent may contain an inorganic salt, an organic acid, an oily component and the like in addition to the essential oil extract of visa tree which is an effective ingredient of the perfume composition of the present invention.

Examples of inorganic salts include sodium chloride, sodium hydrogen carbonate, sodium carbonate, borax, sodium sulfate, sodium sulfide, sodium sesquicarbonate, sodium nitrate, sodium thiosulfate, sodium polyphosphate, sodium phosphate, calcium oxide, magnesium oxide, calcium carbonate, magnesium carbonate, Potassium, and the like, which may be used alone or as a mixture of two or more. These inorganic salts may be added to the bathing agent in an amount of 5% by weight or more, preferably 10% by weight or more, based on the total weight of the bathing agent.

Examples of the organic acid include succinic acid, fumaric acid, malic acid, tartaric acid, citric acid, benzoic acid, etc. These may be used alone or in a mixture of two or more.

These organic acids may be added to the bathing agent in the range of 0.1 to 50% by weight based on the total weight of the bathing agent.

Examples of the oily component include wax, hydrocarbon, higher fatty acid, higher alcohol, ester, silicone oil and the like.

The bath salts may also contain other ingredients commonly used in the art. These components include (a) inorganic acids such as boric acid, meta silicic acid, and silicic anhydride; (b) herbal medicine powders such as fenugreek, bank, ginger, citrus peel, ginger root, peppermint, ginseng and oats; (c) (D) vitamins such as vitamin A, vitamin C, vitamin D and vitamin E, (e) sulfur, mica powder, white clay powder, Loess powder, rice bran carbide, fungicide, preservative and the like.

Such a bathing agent may be prepared by any desired means such as granules, tablets, liquids, powders, and the like.

In another aspect, the present invention relates to an anti-stress composition.

The following Examples and Experimental Examples show that the non-viscous leaf extract has anti-stress activity in both the EEG measurement test and the state anxiety index evaluation test.

Therefore, the anti-stress composition of the present invention is characterized in that it contains an essential oil extract of visa leaf as an active ingredient.

The anti-stress composition of the present invention may be formulated as a body lotion, a shampoo, a hair conditioner, a hair conditioner, a hair treatment, an antiperspirant, a skin lotion, a skin cream, a deodorant, Or a fumigant), a lipstick, a lip balm, a bathing agent, and the like. In particular, it can be made into a cosmetic product such as a skin lotion, a perfume, a bathing agent and the like.

As described above, according to the present invention, a functional perfume composition having anti-stress activity and the like can be provided.

The functional perfume composition of the present invention can be commercialized as an external preparation for skin or a bathing agent of a cosmetic formulation.

FIG. 1 shows the result of EEG measurement before and after inhalation of essential oil extract of visa tree leaves.
FIG. 2 shows the result of the state anxiety index measurement before and after inhaling the essential oil extract of Visa tree leaf.

Hereinafter, the present invention will be described with reference to Examples and Experimental Examples. However, the scope of the present invention is not limited to these examples and experimental examples.

< Example > Manufacture of essential oil extract of visa tree leaves

The visa leaf collected in the area of Bijarim in Jeju area was dried by cold air for 3 days and then pulverized in a pulverizer until the particle size was less than 3 mm. 1 kg of the powder made through this process was passed through a supercritical extraction device ( SFE500R1 , EYESEL CO, Ltd. ), The supercritical state was maintained at a pressure of 350 bar and a temperature of 60 ° C, and the extraction procedure was performed for 3 hours. As a result, an essential oil extract of visa leaf was obtained in a yield of 1.5%.

< Experimental Example > Antistress  Activity evaluation and flavor sensory evaluation

< Experimental Example  1> Antistress  Activity evaluation

& Lt ; Experimental Example 1-1 > Evaluation through electroencephalogram ( EEG ) measurement

Using 14 volunteers as an experimental group, EEG changes were measured before and after inhalation of essential oil extracts of Viza leaves to evaluate the antistress activity of Viza leaves.

The essential oil extract of Viza leaves was inhaled through incense lamps (containing 10% v / v essential oil extract) for 15 minutes. EEG signals were measured by inserting an EEG electrode, The subjects were measured for 3 minutes and then only the middle 2 minutes of the EEG data was used for the analysis.

EEG analysis was performed by using the BrainMap-3D program to obtain only the signals in the prefrontal region including Fp1 and Fp2 and the occipital region including O1 and O2 in the frequency range of 0.5-35 Hz in the Biopac Physiological Data Acquisition System, analysis method. In this experiment, we focused on α-wave analysis such as α-wave index, which is used as a measure for relaxation and stability, and analyzed β-wave, θ-wave, and δ-wave.

The results are shown in Fig.

Referring to FIG. 1, it can be seen that the α wave ratio and the δ wave ratio were decreased compared to before inhalation of the essential oil extract of Visa tree leaf after inhalation.

These changes reflect the relaxed, calm, and concentrated concentration of psychological state, which is a neuroscientific result that scientifically shows the anti-stress efficacy of the extract of Vijayama essential oil. However, the general opinion of the subjects is that the fragrance of the essential oil extract of visa leaf is weak. Therefore, it is desirable to increase the concentration of the essential oil extract of visa tree for the more pronounced EEG adjustment effect.

&Lt; Experimental Example 1-2 > Evaluation using state anxiety index

The state anxiety index (STAI-KYZI) was measured before and after inhalation of the essential oil extract of visa leaf with 14 applicants as an experimental group and is shown in FIG.

Inhalation of the essential oil extract of Viza leaves was carried out for 20 minutes through an incense lamp (containing 10% v / v essential oil extract).

Referring to FIG. 2, it can be confirmed that the state anxiety index was significantly decreased after inhalation of the essential oil extract of Visa tree leaf (p <0.05).

< Experimental Example  2> Fragrance sensory evaluation

<Experimental Example 2-1> Sensory Evaluation Design

(1) Expert opinion survey

Evaluation product: Supernatant extract of visa leaf of Example 1

Assessment Specialists: 5 Aromatherapy and Spa Professionals

Assessment tool: Feel the possibility of commercial application after inhalation of fragrance

Purpose: For the purpose of stress relieving, when the supernatant extract of visa tree is added to various types, the preference of the customer for the fragrance is very important.

(2) Fragrant sensory evaluation of visa wood supercritical extract

Evaluation product: Viscum leaf supercritical extract

Assessment Population: 20 male and female students (9 males, 11 females, mean age 23.6 years) attending Cheju National University

Evaluation tool: Questionnaire of [Fig. 3]

Evaluation method: In the space excluding noise and other fragrance, slowly inhale the fragrance of visa or non-extract contained in the experimental container into the nose, and write the feeling about the fragrance according to the items of the questionnaire. When the sensory test is completed, the experimental space is completely ventilated, ensuring that the following subjects do not have preconceived notions about the fragrance.

<Experimental Example 2-2> Results and Analysis

(1) Expert opinion Opinion survey result

- It is believed that the general preference is high due to the fragrance that reminds of clean nature

- Because it feels various fragrance, it is reasonable to apply it to most age groups.

- Please be careful about the addition amount because there is a part that can feel somewhat strong.

- Skin sensitization potential when added to skin application products.

(2) Sensory evaluation results of visa wood supercritical extract fragrance

(2-1) Results of sensory evaluation

When the mean score is less than 4.0, the image of the smell emotion is positive. If the average value is more than 4.0, the image of the smell emotion is generally evaluated. It is interpreted as low.

The most representative emotions that the participants in the sensory evaluation felt about the fragrance of the visa tree extract were natural (2.10 ± 1.0284) as shown in Figure 4, which graphs the results of [Table 1] and [Table 1] (2.10 ± 0.64027), respectively. Followed by individuality (2.75 ± 1.25132), intensity (2.80 ± 1.54238), and stimulation (2.90 ± 1.29371). (4.90 ± 1.07115), excitement-calm (4.80 ± 1.50787), fuzzy-to-solemn (4.55 ± 1.23438), respectively, are rural, calm, solemn Respectively. (3.15 ± 1.30888), unusual (3.15 ± 1.42441), and natural (3.30 ± 1.21828). The results of this study are as follows.

 (2-2) Sensory Evaluation

In the emotion evaluation of the fragrance of the visa tree supernatant extract of Example 1, an image that is both natural and intense appeared, and it can be expressed as a positive image of a new natural fragrance with strong feeling. It is believed that the freshness and freshness of the visa trees and the somewhat strong fragrance of the leaves of the trees were able to feel the new scent of nature. The fragrance component of the visa tree extract is composed of liminene, torreyal, nuciferol, kayaflavone, pinene, torreyol, etc., and the fragrance component of the visa tree extract is mainly composed of monoterpine or camphor, Of aromatherapy aroma therapy.

Visa tree extracts are known to have excellent antimicrobial action, so they can be combined with the image of fresh fragrance and expected to be used as a functional additive for various antibacterial products. In addition, most of the aromatherapy ingredients depend on imports, and the absence of specialized products in Korea has been a problem, but it is possible to commercialize the essential oil, which is based on the positive image of the visa tree extract aroma, It is considered that a deeper research and development is necessary.

Sensory evaluation result number Item Average Standard Deviation One Satisfied ----------- I am unsatisfied 3.45 1.27630 2 Rare ---------------- Rare 4.50 1.23544 3 Solemn ----------- Solemn 4.55 1.23438 4 It's romantic. 4.20 .76777 5 It is unusual. 3.15 1.42441 6 It is old-fashioned ----------- It is modern 3.70 1.21828 7 It is Urban 4.90 1.07115 8 Intense -------------- weak 2.80 1.54238 9 It is irritating. 2.90 1.29371 10 Warm -------------- Cool 3.75 1.25132 11 Bright ------------------- dark 3.70 1.45458 12 It is youthful -------------- 3.65 1.38697 13 It is natural ----------- It is artificial 2.10 1.02084 14 Excited ------------- calms down 4.80 1.50787 15 It's passionate. 4.15 1.26803 16 I smell flowers -------- I smell flowers 3.70 1.75019 17 It's natural ------------ It's unnatural. 3.30 1.21828 18 It is ----------------- light 2.10 .64072 19 Pleasant ----------------- unpleasant 3.35 1.13671 20 Light ----------------- Heavy 4.25 1.55174 21 It is feminine ------------- It is masculine. 4.20 1.36111 22 I smell ---------------- 3.40 1.39170 23 Unique -------------- Unique 2.75 1.25132 24 Sophisticated ----------------- Crude 3.30 .80131 25 It is fascinating --------------- I feel rejected. 3.95 1.35627 26 Familiar ----------------- Unfamiliar 3.70 1.55935 27 Cool ----------------- frustrating 3.30 1.26074 28 Stable ------------------- Uneasy 3.15 1.30888

Claims (7)

An anti-stress perfume composition comprising essential oil extract of visa tree leaf as an active ingredient.
The method according to claim 1,
Wherein the composition is an external preparation for skin.
The method according to claim 1,
Wherein the composition is a bath composition.
The method according to claim 1,
Wherein the composition is a perfume composition and the perfume composition is a spray or fumigant formulation.
A composition for anti-stress comprising an essential oil extract of visa tree leaf as an active ingredient.
6. The method of claim 5,
Wherein said composition is a bath composition.
6. The method of claim 5,
Wherein the composition is a food composition.

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