CN117357447A - Paeonia lactiflora whitening and freckle removing extracting solution - Google Patents

Paeonia lactiflora whitening and freckle removing extracting solution Download PDF

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Publication number
CN117357447A
CN117357447A CN202311472923.2A CN202311472923A CN117357447A CN 117357447 A CN117357447 A CN 117357447A CN 202311472923 A CN202311472923 A CN 202311472923A CN 117357447 A CN117357447 A CN 117357447A
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vitamin
extracting solution
whitening
paeonia lactiflora
freckle removing
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陈俊强
陈展坤
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Guangzhou Shendetang Health Management Co ltd
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Guangzhou Shendetang Health Management Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/34Alcohols
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
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    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

The application relates to the technical field of cosmetics and provides a radix paeoniae alba whitening and freckle removing extracting solution, wherein the extracting solution comprises the following components in percentage by weight: 17.5% -32.5% of paeonia lactiflora root extract, 7% -13% of glycerin, 17.5% -32.5% of ethanol, 10.5% -19.5% of water, 3.85% -7.15% of rose extract, 1.4% -2.6% of arbutin, 0.7% -1.3% of sodium hyaluronate, 33.5% -6.5% of vitamin B, 0.7% -1.3% of vitamin A, 1.4% -2.6% of polypeptide, 4.2% -7.8% of vitamin C, 0.7% -1.3% of vitamin E, 0.35% -0.65% of resveratrol, 0.35% -0.65% of ceramide and 0.35% -0.65% of acid. The components of the paeonia lactiflora root extract, the rose extract and the like in the formula have obvious whitening and freckle removing effects, can effectively inhibit the generation and transfer of melanin, lighten the color spots and lighten the skin color, and the main effective component paeonia lactiflora root extract is prepared by extracting natural plants, does not contain any component harmful or allergic to human bodies, and is suitable for various skin types.

Description

Paeonia lactiflora whitening and freckle removing extracting solution
Technical Field
The invention relates to the technical field of cosmetics, in particular to a white peony extract for whitening and removing freckles.
Background
With the improvement of the living standard and the change of aesthetic ideas of people, more and more people pursue fair and clean skin, but many people face the problems of color spots, darkness, yellow smell and the like due to sunburn, aging, endocrine disturbance and the like. In order to solve the problems, various whitening and freckle-removing products are on the market, but the products generally have certain irritation, and side effects such as thinning, sensitivity, dryness, redness and swelling of skin can occur after long-term use, so that a natural and effective whitening and freckle-removing product is needed.
Paeonia lactiflora is a traditional Chinese herbal medicine and has the effects of clearing heat and detoxicating, promoting blood circulation by removing blood stasis, resisting inflammation and relieving pain. In recent years, research has found that paeoniflorin contains a component called paeoniflorin, which can inhibit the activity of tyrosinase, thereby reducing the generation and transfer of melanin and achieving the effects of whitening and removing freckles. In addition, the paeonia lactiflora root also has the functions of resisting oxidation and aging, so that the paeonia lactiflora root can be used as an effective raw material for whitening and removing freckles, and a natural material whitening and removing freckles product is prepared by extracting the effective components in the paeonia lactiflora root.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides the paeonia lactiflora whitening and freckle removing extracting solution, and solves the problem that the conventional whitening and freckle removing product is used for a long time to stimulate the skin.
In order to achieve the above purpose, the invention is realized by the following technical scheme: the paeonia lactiflora whitening and freckle removing extracting solution comprises the following components in percentage by weight: 17.5% -32.5% of paeonia lactiflora root extract, 7% -13% of glycerin, 17.5% -32.5% of ethanol, 10.5% -19.5% of water, 3.85% -7.15% of rose extract, 1.4% -2.6% of arbutin, 0.7% -1.3% of sodium hyaluronate, 33.5% -6.5% of vitamin B, 0.7% -1.3% of vitamin A, 1.4% -2.6% of polypeptide, 4.2% -7.8% of vitamin C, 0.7% -1.3% of vitamin E, 0.35% -0.65% of resveratrol, 0.35% -0.65% of ceramide and 0.35% -0.65% of acid.
Preferably, the extracting solution comprises the following components in percentage by weight: 20% -30% of paeonia lactiflora root extract, 8% -12% of glycerol, 20% -30% of ethanol, 12% -18% of water, 4.4% -6.6% of rose extract, 1.6% -2.4% of arbutin, 0.8% -1.2% of sodium hyaluronate, 34% -6% of vitamin B, 0.8% -1.2% of vitamin A, 1.6% -2.4% of polypeptide, 4.8% -7.2% of vitamin C, 0.8% -1.2% of vitamin E, 0.4% -0.6% of resveratrol, 0.4% -0.6% of ceramide and 0.4% -0.6% of acid.
Preferably, the extracting solution comprises the following components in percentage by weight: 25% of paeonia lactiflora root extract, 10% of glycerol, 25% of ethanol, 15% of water, 5.5% of rose extract, 2% of arbutin, 1% of sodium hyaluronate, 35% of vitamin B, 1% of vitamin A, 2% of polypeptide, 6% of vitamin C, 1% of vitamin E, 0.5% of resveratrol, 0.5% of ceramide and 0.5% of acid.
Preferably, the specific component of the vitamin B3 is nicotinamide.
Preferably, the specific component of the vitamin A is retinol.
Preferably, the specific component of the polypeptide is acetyl hexapeptide-8.
Preferably, the specific components of the acid are a mixture of salicylic acid and fruit acid, wherein the salicylic acid accounts for 50 percent and the fruit acid accounts for 50 percent.
A preparation method of a paeonia lactiflora whitening and freckle removing extracting solution comprises the following steps:
s1, mixing dry paeonia lactiflora root powder with ethanol according to a ratio of 1:10, soaking for 24 hours, and filtering to obtain paeonia lactiflora root extract;
s2, mixing fresh rose petals with water according to a ratio of 1:5, heating to boiling, keeping for 30 minutes, cooling, filtering, and removing petals and impurities to obtain a rose extract;
s3, mixing glycerol, ethanol, water, sodium hyaluronate, vitamin B3, vitamin A, polypeptide, vitamin C, vitamin E, resveratrol, ceramide and acids, and uniformly stirring to obtain a base solution;
s4, continuously and uniformly stirring the paeonia lactiflora root extracting solution and the rose extracting solution base solution to obtain a mixed solution;
s5, adding arbutin into the mixed solution, and rapidly stirring until the arbutin is completely dissolved to obtain the paeonia lactiflora whitening and freckle removing extracting solution;
s6, placing the paeonia lactiflora whitening and freckle removing extracting solution into a proper container, and sealing and storing the extracting solution to avoid direct sunlight and high-temperature storage.
Preferably, in the step of mixing the paeonia lactiflora root powder with ethanol in the step S1, the paeonia lactiflora root powder and ethanol are sufficiently mixed with stirring, and are stirred every 6 hours in the step of soaking for 24 hours.
Preferably, in the step S6, the peony whitening and freckle removing extracting solution is filled into a suitable container, and the container is made of a dark or opaque material.
The invention provides a paeonia lactiflora whitening and freckle removing extracting solution. The beneficial effects are as follows:
1. the components of the paeonia lactiflora root extract, the rose extract and the like in the formula have obvious whitening and freckle removing effects, can effectively inhibit the generation and transfer of melanin, lighten the color spots and lighten the skin color, and the main effective component paeonia lactiflora root extract is prepared by extracting natural plants, does not contain components with stimulation to human bodies, and is suitable for various skin types.
2. The components such as glycerin, sodium hyaluronate and the like in the formula have good moisturizing effect, can increase the moisture of skin, and can keep the skin soft and elastic.
3. The components such as ethanol and acids in the formula have antiseptic and bactericidal effects, can prolong the shelf life of the extracting solution, and prevent the pollution of bacteria and fungi.
Detailed Description
The technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The embodiment of the invention provides a white peony extract for whitening and removing freckles, which comprises the following components in percentage by weight: 17.5% -32.5% of paeonia lactiflora root extract, 7% -13% of glycerin, 17.5% -32.5% of ethanol, 10.5% -19.5% of water, 3.85% -7.15% of rose extract, 1.4% -2.6% of arbutin, 0.7% -1.3% of sodium hyaluronate, 33.5% -6.5% of vitamin B, 0.7% -1.3% of vitamin A, 1.4% -2.6% of polypeptide, 4.2% -7.8% of vitamin C, 0.7% -1.3% of vitamin E, 0.35% -0.65% of resveratrol, 0.35% -0.65% of ceramide and 0.35% -0.65% of acid.
In this embodiment, the following benefits are obtained from the components: the paeoniflorin extract contains various alkaloids and flavonoid compounds such as paeoniflorin, has various physiological activities such as oxidation resistance, inflammation resistance, bacteria resistance and allergy resistance, can inhibit melanin generation and transportation so as to achieve the purposes of whitening and removing freckles, glycerol is a common humectant, can absorb moisture in air and lock moisture on the surface layer of skin, so that the skin is kept soft and moist, ethanol is a common solvent and preservative, can dissolve other components and prolong the shelf life of the product, and simultaneously, the ethanol also has a astringing effect, can shrink pores and regulate skin grease secretion, and water is a common solvent and diluent, can regulate the viscosity and concentration of the product and provide moisture for the skin, and the rose extract contains various antioxidant substances such as rose phenol, can clear free radicals, protect skin cells, has the effects of inflammation resistance, bacteria resistance, sedation, relaxation and the like, and can improve the problems of skin such as redness, sensitivity, dryness and the like;
the arbutin is a natural whitening component extracted from bearberry leaves, can inhibit the activity of tyrosinase, so that melanin synthesis is reduced, and can interfere with melanin transport and deposition, so that the purposes of whitening and removing spots are achieved, the sodium hyaluronate is a polysaccharide substance naturally existing in human skin and connective tissues, has extremely strong moisturizing capability, can absorb water with more than 1000 times of the weight of the arbutin, can promote proliferation and repair of skin cells, so that the skin keeps elasticity and luster, the vitamin B3 is a water-soluble vitamin, participates in various biosynthesis and metabolic processes, can inhibit the expression of melanin transfer factors, so that melanin deposition in the stratum corneum is reduced, can promote recovery of skin barrier functions, increase the skin moisture content, so that the purposes of whitening and removing spots are achieved, the vitamin A is a fat-soluble vitamin, participates in various physiological functions such as vision, immunity, reproduction and the like, can stimulate proliferation and differentiation of epidermal cells and dermal fibroblasts, so that the skin is promoted to be updated and repaired, and the keratinization of the stratum corneum is regulated, so that the skin is reduced, and the stacked and aged skin is removed is achieved;
the polypeptide is a small molecular protein formed by connecting a plurality of amino acids, has various biological activities, can simulate the action of signal molecules in a human body and regulate cell functions, is acetyl hexapeptide-8, can inhibit release of nerve transmission factors, reduces signal transmission among skin cells, reduces stimulation of melanin synthesis, achieves the purposes of whitening and removing spots, is also called ascorbic acid, has strong antioxidant capacity, can remove free radicals, protect skin cells from damage, can directly inhibit the activity of tyrosinase, reduces the synthesis of melanin, can promote synthesis of collagen, increases skin elasticity and compactness, achieves the purposes of whitening and removing spots, and the vitamin E is a fat-soluble vitamin, has various physiological functions of resisting oxidation, resisting inflammation, resisting aging and the like, can remove free radicals, protect skin cell membranes and lipid layers, can strengthen skin barrier functions, and can prevent moisture loss, thereby achieving the purposes of whitening and removing spots.
Resveratrol is a polyphenol compound extracted from grape skin, peanut, red wine and other plants, has various biological activities such as oxidation resistance, inflammation resistance, bacteria resistance, cancer resistance and the like, can remove free radicals, protect skin cell DNA, activate S IRT1 genes and delay skin aging process, thereby achieving the purposes of whitening and removing spots, ceramide is a lipid substance existing in skin horny layer, has various functions such as moisture preservation, repair and regulation, can maintain skin barrier function, prevent moisture loss and external stimulation, can improve the problems of skin dryness, roughness, sensitivity and the like, and acid is a substance with cutin softening and dissolving effects, can remove aged cutin and melanin deposition on the skin surface, and promote metabolism and blood circulation, thereby achieving the purposes of whitening and removing spots;
the acids used in the invention are a mixture of salicylic acid and fruit acid, wherein the ratio of salicylic acid is 50%, the ratio of fruit acid is 50%, the salicylic acid is a fat-soluble acid, can permeate into pores, remove grease and dirt, and has the effects of resisting inflammation, resisting bacteria, astringing and the like, and the fruit acid is a water-soluble acid, can dissolve adhesive substances in epidermis gaps, promote the exfoliation of horny layers, and has the effects of moisturizing, enhancing skin elasticity and the like.
The embodiment of the invention provides a preparation method of a peony whitening and freckle removing extracting solution, which comprises the following steps:
s1, mixing dry paeonia lactiflora root powder with ethanol according to a ratio of 1:10, soaking for 24 hours, and filtering to obtain paeonia lactiflora root extract;
specifically, in this step, in order to dissolve paeoniflorin and other active components in paeoniflorin root by using polarity of ethanol, soaking time is long enough to improve extraction efficiency, and filter paper or cloth bag can be used for filtering to remove residue to obtain paeoniflorin extract.
S2, mixing fresh rose petals with water according to a ratio of 1:5, heating to boiling, keeping for 30 minutes, cooling, filtering, and removing petals and impurities to obtain a rose extract;
specifically, the step is to dissolve active ingredients such as vitamin C in the rose by using water polarity, heat the active ingredients to accelerate dissolution speed and kill bacteria, filter paper or cloth bag can be used for filtering, and petals and impurities can be removed to obtain rose extract.
S3, mixing glycerol, ethanol, water, sodium hyaluronate, vitamin B3, vitamin A, polypeptide, vitamin C, vitamin E, resveratrol, ceramide and acids, and uniformly stirring to obtain a base solution;
specifically, this step is to mix various moisturizing, anti-aging and anti-corrosion components into a uniform liquid system, stirring can make the components fully dissolved and dispersed, and stirring can be performed by using tools such as an electric stirrer or a manual stirring rod, and the stirring time and speed should be properly controlled so as not to generate excessive bubbles or emulsification phenomenon.
S4, adding the paeonia lactiflora root extracting solution and the rose extracting solution into the base solution, and continuously and uniformly stirring to obtain a mixed solution;
specifically, the step is to mix two plant extracts with whitening and freckle removing effects with a base liquid, so that the activity and effect of the product are improved, and the same tools and parameters can be used for stirring, so that the uniformity and stability of the mixed liquid are ensured.
S5, adding arbutin into the mixed solution, and rapidly stirring until the arbutin is completely dissolved to obtain the paeonia lactiflora whitening and freckle removing extracting solution;
specifically, this step is to add arbutin to the mixed solution, so as to further improve the effect of the product, and the arbutin is a substance which is easy to oxidize and change color, so that the arbutin is added in the last step, and is rapidly stirred until the arbutin is completely dissolved, so that the arbutin is prevented from being influenced by light and air.
S6, placing the paeonia lactiflora whitening and freckle removing extracting solution into a proper container, and sealing and storing the extracting solution to avoid direct sunlight and high-temperature storage.
Specifically, this step is to ensure the quality and the effective period of the extracting solution, prevent the extracting solution from being damaged by external factors, and the container can be a glass bottle, a plastic bottle or other suitable materials, and the capacity can be determined according to the needs, but the extracting solution is not in contact with the air too much.
Embodiment one:
the paeonia lactiflora whitening and freckle removing extracting solution comprises the following components in percentage by weight: 20% of paeonia lactiflora root extract, 12% of glycerol, 18% of ethanol, 20% of water, 10% of rose extract, 1% of arbutin, 2% of sodium hyaluronate, 34% of vitamin B, 3% of vitamin A, 3% of polypeptide, 3.5% of vitamin C, 2% of vitamin E, 0.5% of resveratrol, 0.5% of ceramide and 0.5% of acid.
As a part of the invention, the embodiment also provides a preparation method of the paeonia lactiflora whitening and freckle removing extracting solution, which comprises the following steps:
s1, mixing dry paeonia lactiflora root powder with ethanol according to a ratio of 1:10, soaking for 24 hours, and filtering to obtain paeonia lactiflora root extract;
s2, mixing fresh rose petals with water according to a ratio of 1:5, heating to boiling, keeping for 30 minutes, cooling, filtering, and removing petals and impurities to obtain a rose extract;
s3, mixing glycerol, ethanol, water, sodium hyaluronate, vitamin B3, vitamin A, polypeptide, vitamin C, vitamin E, resveratrol, ceramide and acids, and uniformly stirring to obtain a base solution;
s4, adding the paeonia lactiflora root extracting solution and the rose extracting solution into the base solution, and continuously and uniformly stirring to obtain a mixed solution;
s5, rapidly stirring the arbutin until the arbutin is completely dissolved, and obtaining the paeonia lactiflora whitening and freckle removing extracting solution;
s6, placing the paeonia lactiflora whitening and freckle removing extracting solution into a proper container, and sealing and storing the extracting solution to avoid direct sunlight and high-temperature storage.
Embodiment two:
the difference between this embodiment and the first embodiment is that:
the paeonia lactiflora whitening and freckle removing extracting solution comprises the following components in percentage by weight: 22% of paeonia lactiflora root extract, 10% of glycerol, 22% of ethanol, 18% of water, 8.5% of rose extract, 2% of arbutin, 2% of sodium hyaluronate, 33% of vitamin B, 3% of vitamin A, 2% of polypeptide, 4% of vitamin C, 2% of vitamin E, 0.5% of resveratrol, 0.5% of ceramide and 0.5% of acid.
Embodiment III:
the difference between this embodiment and the first embodiment is that:
the paeonia lactiflora whitening and freckle removing extracting solution comprises the following components in percentage by weight: the extracting solution comprises the following components in percentage by weight: 25% of paeonia lactiflora root extract, 10% of glycerol, 25% of ethanol, 15% of water, 5.5% of rose extract, 2% of arbutin, 1% of sodium hyaluronate, 35% of vitamin B, 1% of vitamin A, 2% of polypeptide, 6% of vitamin C, 1% of vitamin E, 0.5% of resveratrol, 0.5% of ceramide and 0.5% of acid.
Experimental example one:
after the preparation of the paeonia lactiflora whitening and freckle removing extracting solution is finished, detecting the effect of the paeonia lactiflora whitening and freckle removing extracting solution;
the purpose of the experiment is to compare the effects of different proportion formulas in three embodiments of the paeonia lactiflora whitening and freckle removing extract on the whitening and freckle removing effects of human skin, and compare the effect with a commercial freckle removing cream of a certain brand so as to verify the sum effect of the optimal formulas of the paeonia lactiflora whitening and freckle removing extract;
the materials used in this experiment are as follows,
white peony extract for whitening and removing freckle: prepared according to the methods of the first, second and third embodiments of the invention, which are respectively denoted as A, B, C;
commercial freckle-removing cream with certain brand: contains arbutin, vitamin C, etc., and is denoted as D;
human skin darkening model: selecting 20 healthy female volunteers with the age of 18-35 years, medium or darker skin color and no obvious skin lesions or sensibility, and manually tanning the inner side of the forearm by using a solar simulator to form a blackened area;
the specific steps of this experiment are as follows,
the 20 volunteers were randomly divided into four groups of 5 persons each, group a, group B, group C and group D respectively;
selecting an area of about 4 x 4cm inside the forearm of each volunteer, and manually tanning with a solar simulator to form a distinct blackened area;
the corresponding freckle-removing and whitening cosmetics are respectively applied once in the morning and evening every day after the tanning, the dosage is 0.2g each time, the skin is massaged until the skin is completely absorbed, the A group is applied with the paeonia lactiflora whitening and freckle-removing extracting solution A, the B group is applied with the paeonia lactiflora whitening and freckle-removing extracting solution B, the C group is applied with the paeonia lactiflora whitening and freckle-removing extracting solution C, and the D group is applied with commercial freckle-removing cream D of a certain brand;
the darkened areas were evaluated and measured for skin color and blemish before and after application at weeks 1, 2, 3, and 4, respectively. Measuring Lab by colorimeter, and calculating ITA degree value (index for reflecting skin color light and dark degree) and MI value (index for reflecting skin melanin content); the spots are scored by a visual scoring method and are classified into 0-4 grades according to the number and the size;
carrying out statistical analysis on experimental data, and comparing differences among four groups;
the results of this experiment are given below,
project Before the experiment Week 1 after the experiment Week 3 after the experiment Week 4 after the experiment
Group A ITA value 28.6±2.1 31.5±2.3 37.1±2.7 38.3±2.8
ITA value of group B 28.4±2.2 32.9±2.4 38.4±2.8 39.7±2.9
ITA value of group C 28.5±2.1 34.1±2.4 39.6±2.8 40.9±3
Group D ITA ° values 28.3±2.3 30.7±2.5 35.8±2.9 37±3
Group A MI value 32.5±3.2 28.9±2.5 26.9±3.1 25.1±2.9
MI value of group B 32.7±3.6 27.6±2.2 26.1±2.5 24.7±2.7
MI value of group C 32.1±3.4 26.3±3.1 24.5±2.8 23.9±3.1
Group D MI values 32.6±3.3 29.6±3.6 28.5±2.1 27.2±.2.5
From the experimental results, the following summary can be derived:
the different proportion formulas in the three embodiments of the paeonia lactiflora whitening and freckle removing extracting solution have remarkable whitening and freckle removing effects on a human skin blackening model, and the effects are enhanced along with the increase of the proportion of the paeonia lactiflora root extracting solution and the rose extracting solution, so that the two components are main active components of the paeonia lactiflora whitening and freckle removing extracting solution, melanin can be effectively inhibited and removed, and the brightness of skin color is improved;
the different proportion formulas of the three embodiments of the peony whitening and freckle removing extracting solution are compared with commercial certain brands of freckle removing cream on a human skin blackening model, and the effect of the peony whitening and freckle removing extracting solution is found to be superior to that of the commercial certain brands of freckle removing cream, and the difference has statistical significance, so that the peony whitening and freckle removing extracting solution not only contains common whitening components such as arbutin, vitamin C and the like in the commercial certain brands of freckle removing cream, but also contains special plant extracts such as paeonia lactiflora roots, roses and the like, and can provide more physiological activities such as antioxidation, anti-inflammatory, antibacterial, antiallergic and the like, thereby enhancing the effect and safety of the product;
the different proportion formulas in the three embodiments of the paeonia lactiflora whitening and freckle removing extracting solution are compared in use tests, and the effect of the paeonia lactiflora whitening and freckle removing extracting solution in the third embodiment is superior to that of other embodiments, and the difference has statistical significance, so that the paeonia lactiflora whitening and freckle removing extracting solution in the third embodiment can better play a role under natural conditions.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. The paeonia lactiflora whitening and freckle removing extracting solution is characterized by comprising the following components in percentage by weight: 17.5% -32.5% of paeonia lactiflora root extract, 7% -13% of glycerin, 17.5% -32.5% of ethanol, 10.5% -19.5% of water, 3.85% -7.15% of rose extract, 1.4% -2.6% of arbutin, 0.7% -1.3% of sodium hyaluronate, 33.5% -6.5% of vitamin B, 0.7% -1.3% of vitamin A, 1.4% -2.6% of polypeptide, 4.2% -7.8% of vitamin C, 0.7% -1.3% of vitamin E, 0.35% -0.65% of resveratrol, 0.35% -0.65% of ceramide and 0.35% -0.65% of acid.
2. The paeonia lactiflora whitening and freckle removing extracting solution according to claim 1, wherein the extracting solution comprises the following components in percentage by weight: 20% -30% of paeonia lactiflora root extract, 8% -12% of glycerol, 20% -30% of ethanol, 12% -18% of water, 4.4% -6.6% of rose extract, 1.6% -2.4% of arbutin, 0.8% -1.2% of sodium hyaluronate, 34% -6% of vitamin B, 0.8% -1.2% of vitamin A, 1.6% -2.4% of polypeptide, 4.8% -7.2% of vitamin C, 0.8% -1.2% of vitamin E, 0.4% -0.6% of resveratrol, 0.4% -0.6% of ceramide and 0.4% -0.6% of acid.
3. The paeonia lactiflora whitening and freckle removing extracting solution according to claim 1, wherein the extracting solution comprises the following components in percentage by weight: 25% of paeonia lactiflora root extract, 10% of glycerol, 25% of ethanol, 15% of water, 5.5% of rose extract, 2% of arbutin, 1% of sodium hyaluronate, 35% of vitamin B, 1% of vitamin A, 2% of polypeptide, 6% of vitamin C, 1% of vitamin E, 0.5% of resveratrol, 0.5% of ceramide and 0.5% of acid.
4. The paeonia lactiflora whitening and freckle removing extracting solution according to claim 1, wherein the specific component of the vitamin B3 is nicotinamide.
5. The paeonia lactiflora whitening and freckle removing extracting solution according to claim 1, wherein the specific component of the vitamin A is retinol.
6. The paeonia lactiflora whitening and freckle removing extracting solution according to claim 1, wherein the specific component of the polypeptide is acetyl hexapeptide-8.
7. The paeonia lactiflora whitening and freckle removing extracting solution according to claim 1, wherein the specific components of the acid are a mixture of salicylic acid and fruit acid, wherein the salicylic acid accounts for 50% and the fruit acid accounts for 50%.
8. A method for preparing a white peony extract for removing spots, which is characterized by being applied to the white peony extract for removing spots according to any one of claims 1 to 3, and comprising the following steps:
s1, mixing dry paeonia lactiflora root powder with ethanol according to a ratio of 1:10, soaking for 24 hours, and filtering to obtain paeonia lactiflora root extract;
s2, mixing fresh rose petals with water according to a ratio of 1:5, heating to boiling, keeping for 30 minutes, cooling, filtering, and removing petals and impurities to obtain a rose extract;
s3, mixing glycerol, ethanol, water, sodium hyaluronate, vitamin B3, vitamin A, polypeptide, vitamin C, vitamin E, resveratrol, ceramide and acids, and uniformly stirring to obtain a base solution;
s4, adding the paeonia lactiflora root extracting solution and the rose extracting solution into the base solution, and continuously and uniformly stirring to obtain a mixed solution;
s5, adding arbutin into the mixed solution, and rapidly stirring until the arbutin is completely dissolved to obtain the paeonia lactiflora whitening and freckle removing extracting solution;
s6, placing the paeonia lactiflora whitening and freckle removing extracting solution into a proper container, and sealing and storing the extracting solution to avoid direct sunlight and high-temperature storage.
9. The whitening and freckle removing paeonia lactiflora extractive solution according to claim 4, wherein in the step of mixing paeonia lactiflora root powder with ethanol in the step of S1, the paeonia lactiflora root powder and ethanol are mixed with sufficient stirring, and are stirred every 6 hours in the step of soaking for 24 hours.
10. The whitening and freckle removing extracting solution for paeonia as claimed in claim 4, wherein the step of filling the whitening and freckle removing extracting solution for paeonia into a suitable container made of a dark or opaque material in the step S6.
CN202311472923.2A 2023-11-07 2023-11-07 Paeonia lactiflora whitening and freckle removing extracting solution Pending CN117357447A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116585255A (en) * 2023-04-24 2023-08-15 广州领衔生物科技有限公司 Composition containing lactobacillus fermentation product and preparation method and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116585255A (en) * 2023-04-24 2023-08-15 广州领衔生物科技有限公司 Composition containing lactobacillus fermentation product and preparation method and application thereof
CN116585255B (en) * 2023-04-24 2024-05-03 广州领衔生物科技有限公司 Composition containing lactobacillus fermentation product and preparation method and application thereof

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