CN110538093A - polypeptide repair liquid and preparation method thereof - Google Patents
polypeptide repair liquid and preparation method thereof Download PDFInfo
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- CN110538093A CN110538093A CN201910987684.1A CN201910987684A CN110538093A CN 110538093 A CN110538093 A CN 110538093A CN 201910987684 A CN201910987684 A CN 201910987684A CN 110538093 A CN110538093 A CN 110538093A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention belongs to the technical field of cosmetics, and particularly relates to a polypeptide repairing liquid and a preparation method thereof. The polypeptide repair liquid is prepared by utilizing various peptide raw materials, is rich in strong repair components of acetyl hexapeptide-8, palmitic acid tripeptide-1, tripeptide-1 copper, acetyl tetrapeptide-5, palmitoyl tetrapeptide-7 and carnosine, has synergistic interaction, can dissolve and repair damaged cells in a human body, promotes a microcirculation system to remove decomposed fat, solves the problem of poor cell protein repair, achieves the aim of repair, is rich in raw material sources, reduces the production cost and improves the product competitiveness.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a polypeptide repairing liquid and a preparation method thereof.
background
The skin is an organ which is wrapped on the surface of the body, is directly contacted with the external environment, has the functions of protecting, excreting, regulating body temperature, sensing external stimulation and the like, and is the largest organ in human body organs. The skin is divided into two layers of epidermis and dermis, the epidermis is arranged on the surface of the skin, the epidermis is divided into five layers from top to bottom, the five layers comprise a cuticle layer, a transparent layer, a granular layer, a spinous layer and a basal layer, and the cuticle layer has the functions of protection, water resistance and bacteria resistance; the transparent layer has effects of controlling skin moisture and preventing water loss; the particle layer prevents the invasion of foreign matters and filters ultraviolet rays; the spinous layer has cell division and proliferation capacity; the basal layer contains melanocytes, and the melanin produced can prevent ultraviolet rays from damaging internal tissues. The dermis is dense connective tissue with many elastic fibers and collagen fibers, and is elastic and tough. The dermis is thicker than the epidermis and is rich in blood vessels and nerves. There is subcutaneous tissue beneath the skin, which is loose connective tissue with a large number of fat cells. When the skin is affected by internal and external adverse factors and weak in resistance, it causes damage to skin tissues, thereby allowing the skin to exhibit: the skin surface is thin, and red blood filaments can be seen; uneven skin tone; drying and water shortage; itching, erythema, etc. However, the cosmetics in the prior art emphasize water replenishing for damaged skin once, but because the skin is composed of multiple layers, water cannot be replenished once, and the effects of water replenishing and sensitive repair can be achieved as long as the water can reach the deep layer of the skin. Furthermore, with aging, the metabolism of the skin becomes slow, the division and proliferation ability of basal cells become weak, and this results in an increase in the proportion of aged cells in the skin and the skin begins to age. Beauty is pursued by every female, the existing similar cosmetics only aim at skin beautifying and ultraviolet ray damage prevention, the used chemical substances are many, the health of the human body is not facilitated, the effect is not obvious, and the effect of deep repair cannot be achieved.
Propylene glycol can be used as humectant in cosmetic in combination with glycerin or sorbitol.
the xanthan gum is natural gum, is mainly used as a thickening agent and an emulsion stabilizer, is not sticky and easy to dissolve in water, is emulsified into hydrophilic viscous gum, has higher safety and can be used safely.
Allantoin is a non-toxic, tasteless, non-irritant and non-allergenic white powder, is mainly used as a skin conditioner and a protective agent, and can help skin to resist inflammation, relieve and promote cell repair. Allantoin can reduce adhesion of stratum corneum cells and accelerate epidermal cell renewal, and some cosmetics containing tartaric acid and vitamin A with irritation or after-sun repair products with antiinflammatory and tranquilizing effects can be added with allantoin to enhance its repair ability.
Polyacrylic acid is used as adhesive, emulsion stabilizer and film forming agent in cosmetics.
Sodium hyaluronate is one of the constituents of human skin, is an acidic sticky sugar which is widely distributed in human body, exists in a matrix of connective tissue, has a good moisturizing effect, and is widely used in the field of cosmetics.
Acetyl hexapeptide-8 is a bioactive polypeptide, which can reduce existing facial wrinkles and effectively prevent new wrinkles, and can reduce muscle contraction by inhibiting release of neurotransmitter acetylcholine (acetylcholine), thereby achieving the purpose of reducing the generation of dynamic lines and expression lines.
Palmitoyl tripeptide-1 is formed by combining wheat and soy protein, and the component can stimulate collagen synthesis.
Inositol is a hexa-cyclohexanol type monosaccharide with extremely wide distribution, exists in almost all plants, and is generally extracted by taking calcium phytate as a raw material. Inositol has the same effect as biotin and vitamin B, has the functions of nourishing, moisturizing and conditioning the skin, and can increase the luster of the skin; the moisturizing capability of the product is equal to that of glycerin, and the product does not generate sticky feeling with glycerin when used at high concentration; inositol has good transdermal permeability, can promote the permeation of other components, and can be used as adjuvant for skin-activating cream and hair-growing water.
tripeptide-1 copper, also known as copper trisepeptide, copper bluepetide. The copper peptide and the copper compound thereof can be used as an activator and an antioxidant for tissue remodeling, and the copper peptide is also a signal peptide, so that the degradation of a large number of collagen aggregates outside the scar, the synthesis of normal collagen of the skin, the generation of elastin, proteoglycan and glucosaminan, the growth speed and migration of different cell types, inflammation resistance and antioxidant reaction are promoted.
The acetyl tetrapeptide-5 is used as a humectant, a conditioner and the like, and has better anti-wrinkle capacity.
The creatine can effectively prevent and treat skin aging and injury caused by ultraviolet irradiation, promote skin regeneration, prevent skin dryness, relieve pain and itching or other ill-name maladapted symptoms of sensitive skin, and accelerate the healing of injured skin. The creatine is easy to be formulated and can be used together with all cosmetic auxiliaries.
Palmitoyl tetrapeptide-7 can be used for compacting skin by stimulating laminin (Lamininv) type IV and VII collagen, reducing interleukin (interleukin-6) generation, eliminating inflammation, preventing injury, and preventing wrinkle formation, relaxation and uneven skin color.
The carnosine can promote cell metabolism and delay senility.
Methylparaben is a paraben preservative and is widely used in cosmetics. The preservative of the paraben has stronger antibacterial effect on mould and microzyme and slightly poorer antibacterial effect, and mainly plays an antibacterial role by destroying cell membranes of microorganisms, denaturing proteins in cells and inhibiting the activity of cell respiratory enzymes and a transfer enzyme system.
The polysorbate-20 is fatty acid, can be dissolved in water, and can be used as emulsifier in cosmetic for increasing smoothness of product.
Panthenol, also known as provitamin B5, is used primarily as a moisturizer and skin conditioner.
Disodium EDTA is mainly used as chelating agent and has stabilizing effect in cosmetics, and mineral chelating agent has synergistic antiseptic effect. And has a certain synergistic effect on an anticorrosion system and an antioxidant system.
Phenoxyethanol has a slightly aromatic odor. The water-soluble cationic surfactant is stable at the temperature of below 80 ℃, has stable and effective pH value of 3-10, can be compatible with anionic and cationic surfactants, and can be inactivated in high-ethoxyl compounds.
Disclosure of Invention
The invention aims to provide a polypeptide repairing liquid and a preparation method thereof. The polypeptide repair liquid is prepared by utilizing various peptide raw materials, is rich in strong repair components of acetyl hexapeptide-8, palmitic acid tripeptide-1, tripeptide-1 copper, acetyl tetrapeptide-5, palmitoyl tetrapeptide-7 and carnosine, has synergistic interaction, can dissolve and repair damaged cells in a human body, promotes a microcirculation system to remove decomposed fat, solves the problem of poor cell protein repair, achieves the aim of repair, is rich in raw material sources, reduces the production cost and improves the product competitiveness.
The technical scheme of the invention is as follows:
A preparation method of a polypeptide repairing liquid comprises the following steps:
(1) Taking 3-5 parts by weight of propylene glycol, 0.3-0.5 part by weight of xanthan gum, 0.1-0.2 part by weight of allantoin, 0.1-0.2 part by weight of polyacrylic acid, 0.1-0.2 part by weight of sodium hyaluronate, 0.1-0.3 part by weight of methylparaben, 0.05-0.1 part by weight of disodium EDTA and 64-87 parts by weight of deionized water, stirring, mixing uniformly, and heating to 70-90 ℃ to obtain a phase A material;
(2) Homogenizing and emulsifying the phase A material at the temperature of 70-90 ℃, and then stirring and cooling to obtain an emulsified material;
(3) and (3) when the emulsified material in the step (2) is cooled to 35-45 ℃, adding 1-3 parts by weight of acetyl hexapeptide-8, 1-3 parts by weight of palmitoyl tripeptide-1, 1-3 parts by weight of inositol, 1-3 parts by weight of tripeptide-1 copper, 1-3 parts by weight of acetyl tetrapeptide-5, 1-3 parts by weight of creatine, 1-3 parts by weight of palmitoyl tetrapeptide-7, 1-3 parts by weight of carnosine, 1-3 parts by weight of polysorbate-20, 0.5-0.8 part by weight of panthenol and 0.2-0.8 part by weight of phenoxyethanol, and uniformly stirring to obtain the polypeptide repairing liquid.
further, the operation in step (1) is carried out in an aqueous phase kettle.
Further, the homogenizing and emulsifying in the step (2) are carried out in an emulsifying pot.
Further, the homogenizing and emulsifying time in the step (2) is controlled to be 3-5 minutes.
the polypeptide repairing liquid prepared by the method.
A facial mask containing the polypeptide repairing liquid is provided.
The invention has the following beneficial effects:
1. The polypeptide repairing liquid can repair damaged skin, consolidate and repair shaping, regenerate cells and enhance antibody and metabolic capability.
2. the polypeptide repairing liquid has no side effect, does not rebound after repairing, can keep the skin elasticity, does not relax the skin, delays senility and brightens the skin color.
3. The polypeptide repairing liquid has rich raw material sources, can reduce the production cost and improve the product competitiveness.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to the following embodiments, but the present invention is not limited thereto.
Example 1
a preparation method of a polypeptide repairing liquid comprises the following steps:
(1) Adding 4 parts by weight of propylene glycol, 0.3 part by weight of xanthan gum, 0.15 part by weight of allantoin, 0.1 part by weight of polyacrylic acid, 0.2 part by weight of sodium hyaluronate, 0.12 part by weight of methyl hydroxybenzoate, 0.08 part by weight of EDTA disodium and 68 parts by weight of deionized water into a water phase pot in sequence, uniformly mixing, and heating to 85 ℃ to obtain a phase A material;
(2) pumping the phase A material into an emulsifying pot, stirring at a medium speed, keeping the temperature at 85 ℃, homogenizing and emulsifying for 3 minutes, and then stirring and cooling to obtain an emulsified material;
(3) and (3) when the emulsified material in the step (2) is cooled to 40 ℃, adding 3 parts by weight of acetyl hexapeptide-8, 1 part by weight of palmitoyl tripeptide-1, 2 parts by weight of inositol, 1.5 parts by weight of tripeptide-1 copper, 3 parts by weight of acetyl tetrapeptide-5, 2 parts by weight of creatine, 2.5 parts by weight of palmitoyl tetrapeptide-7, 3 parts by weight of carnosine, 2 parts by weight of polysorbate-20, 0.6 part by weight of panthenol and 0.4 part by weight of phenoxyethanol, and uniformly stirring to obtain the polypeptide repairing liquid.
The polypeptide repairing liquid prepared by the embodiment has an obvious repairing effect on symptoms such as damaged skin; the skin can be prevented from rebounding again after being repaired, so that the customer has no worry about after repairing; no preservative is added, so that the safety is ensured.
example 2
A preparation method of a polypeptide repairing liquid comprises the following steps:
(1) Adding 3 parts by weight of propylene glycol, 0.3 part by weight of xanthan gum, 0.1 part by weight of allantoin, 0.2 part by weight of polyacrylic acid, 0.12 part by weight of sodium hyaluronate, 0.15 part by weight of methylparaben, 0.06 part by weight of EDTA disodium and 75 parts by weight of deionized water into a water phase pot in sequence, uniformly mixing, and heating to 80 ℃ to obtain a phase A material;
(2) Pumping the phase A material into an emulsifying pot, stirring at a medium speed, keeping the temperature at 80 ℃, homogenizing and emulsifying for 5 minutes, and then stirring and cooling to obtain an emulsified material;
(3) and (3) when the emulsified material in the step (2) is cooled to 40 ℃, adding 2 parts by weight of acetyl hexapeptide-8, 2 parts by weight of palmitoyl tripeptide-1, 2 parts by weight of inositol, 1 part by weight of tripeptide-1 copper, 1 part by weight of acetyl tetrapeptide-5, 2 parts by weight of creatine, 3 parts by weight of palmitoyl tetrapeptide-7, 3 parts by weight of carnosine, 3 parts by weight of polysorbate-20, 0.7 part by weight of panthenol and 0.4 part by weight of phenoxyethanol, and uniformly stirring to obtain the polypeptide repairing liquid.
The polypeptide repairing liquid prepared by the embodiment has an obvious repairing effect on symptoms such as damaged skin; the skin can be prevented from rebounding again after being repaired, so that the customer has no worry about after repairing; no preservative is added, so that the safety is ensured.
Example 3
A preparation method of a polypeptide repairing liquid comprises the following steps:
(1) taking 4 parts by weight of propylene glycol, 0.5 part by weight of xanthan gum, 0.15 part by weight of allantoin, 0.2 part by weight of polyacrylic acid, 0.13 part by weight of sodium hyaluronate, 0.18 part by weight of methylparaben, 0.1 part by weight of EDTA disodium and 80 parts by weight of deionized water, sequentially adding the materials into a water phase pot, uniformly mixing, and heating to 82 ℃ to obtain a phase A material;
(2) Pumping the phase A material into an emulsifying pot, stirring at a medium speed, keeping the temperature at 82 ℃, homogenizing and emulsifying for 4 minutes, and then stirring and cooling to obtain an emulsified material;
(3) And (3) when the emulsified material in the step (2) is cooled to 42 ℃, adding 2 parts by weight of acetyl hexapeptide-8, 1 part by weight of palmitoyl tripeptide-1, 2 parts by weight of inositol, 2 parts by weight of tripeptide-1 copper, 3 parts by weight of acetyl tetrapeptide-5, 2 parts by weight of creatine, 3 parts by weight of palmitoyl tetrapeptide-7, 3 parts by weight of carnosine, 2 parts by weight of polysorbate-20, 0.6 part by weight of panthenol and 0.6 part by weight of phenoxyethanol, and uniformly stirring to obtain the polypeptide repairing liquid.
the polypeptide repairing liquid prepared by the embodiment has an obvious repairing effect on symptoms such as damaged skin; the skin can be prevented from rebounding again after being repaired, so that the customer has no worry about after repairing; no preservative is added, so that the safety is ensured.
Example 4
A preparation method of a polypeptide repairing liquid comprises the following steps:
(1) Adding 5 parts by weight of propylene glycol, 0.4 part by weight of xanthan gum, 0.15 part by weight of allantoin, 0.1 part by weight of polyacrylic acid, 0.1 part by weight of sodium hyaluronate, 0.15 part by weight of methyl hydroxybenzoate, 0.07 part by weight of EDTA disodium and 69 parts by weight of deionized water into a water phase pot in sequence, uniformly mixing, and heating to 75 ℃ to obtain a phase A material;
(2) Pumping the phase A material into an emulsifying pot, stirring at medium speed, keeping the temperature at 75 ℃, homogenizing and emulsifying for 5 minutes, and then stirring and cooling to obtain an emulsified material;
(3) And (3) when the emulsified material in the step (2) is cooled to 38 ℃, adding 2 parts by weight of acetyl hexapeptide-8, 1 part by weight of palmitoyl tripeptide-1, 1.8 parts by weight of inositol, 1.2 parts by weight of tripeptide-1 copper, 1 part by weight of acetyl tetrapeptide-5, 2 parts by weight of creatine, 3 parts by weight of palmitoyl tetrapeptide-7, 3 parts by weight of carnosine, 2 parts by weight of polysorbate-20, 0.8 part by weight of panthenol and 0.4 part by weight of phenoxyethanol, and uniformly stirring to obtain the polypeptide repairing liquid.
The polypeptide repairing liquid prepared by the embodiment has an obvious repairing effect on symptoms such as damaged skin; the skin can be prevented from rebounding again after being repaired, so that the customer has no worry about after repairing; no preservative is added, so that the safety is ensured.
the above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (6)
1. The preparation method of the polypeptide repairing liquid is characterized by comprising the following steps:
(1) Taking 3-5 parts by weight of propylene glycol, 0.3-0.5 part by weight of xanthan gum, 0.1-0.2 part by weight of allantoin, 0.1-0.2 part by weight of polyacrylic acid, 0.1-0.2 part by weight of sodium hyaluronate, 0.1-0.3 part by weight of methylparaben, 0.05-0.1 part by weight of disodium EDTA and 64-87 parts by weight of deionized water, stirring, mixing uniformly, and heating to 70-90 ℃ to obtain a phase A material;
(2) Homogenizing and emulsifying the phase A material at the temperature of 70-90 ℃, and then stirring and cooling to obtain an emulsified material;
(3) And (3) when the emulsified material in the step (2) is cooled to 35-45 ℃, adding 1-3 parts by weight of acetyl hexapeptide-8, 1-3 parts by weight of palmitoyl tripeptide-1, 1-3 parts by weight of inositol, 1-3 parts by weight of tripeptide-1 copper, 1-3 parts by weight of acetyl tetrapeptide-5, 1-3 parts by weight of creatine, 1-3 parts by weight of palmitoyl tetrapeptide-7, 1-3 parts by weight of carnosine, 1-3 parts by weight of polysorbate-20, 0.5-0.8 part by weight of panthenol and 0.2-0.8 part by weight of phenoxyethanol, and uniformly stirring to obtain the polypeptide repairing liquid.
2. The polypeptide repairing liquid and the preparation method thereof according to claim 1, wherein the operation in the step (1) is performed in an aqueous pot.
3. The polypeptide repairing liquid and the preparation method thereof according to claim 1, wherein the homogenizing and emulsifying in the step (2) are performed in an emulsifying pot.
4. the polypeptide repairing liquid and the preparation method thereof according to claim 1, wherein the time for homogenizing and emulsifying in the step (2) is controlled to be 3-5 minutes.
5. a polypeptide repair solution prepared by any one of the methods of claims 1 to 4.
6. A facial mask comprising the polypeptide restoration solution of claim 5.
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| CN201910987684.1A CN110538093A (en) | 2019-10-17 | 2019-10-17 | polypeptide repair liquid and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053719A (en) * | 2020-01-06 | 2020-04-24 | 广州品域美妆创新科技有限公司 | Soothing and whitening composition containing vitamin B12 and application thereof |
| CN111973519A (en) * | 2020-09-11 | 2020-11-24 | 广州子芽生物科技有限公司 | Composition with repairing and anti-aging effects and application of composition in cosmetics |
| CN112029723A (en) * | 2020-09-18 | 2020-12-04 | 郑州佐爵生物科技有限公司 | Method for culturing umbilical cord blood CIK cells in vitro |
| CN112972284A (en) * | 2021-03-05 | 2021-06-18 | 山东科思达美生物科技有限公司 | Polypeptide composition for eye care and application |
| CN113576975A (en) * | 2021-08-25 | 2021-11-02 | 广州市雅创化妆品有限公司 | Easily-absorbed anti-aging composition and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110151597A (en) * | 2019-05-14 | 2019-08-23 | 夏战利 | A kind of polypeptide repair latex and preparation method thereof |
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2019
- 2019-10-17 CN CN201910987684.1A patent/CN110538093A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110151597A (en) * | 2019-05-14 | 2019-08-23 | 夏战利 | A kind of polypeptide repair latex and preparation method thereof |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053719A (en) * | 2020-01-06 | 2020-04-24 | 广州品域美妆创新科技有限公司 | Soothing and whitening composition containing vitamin B12 and application thereof |
| CN111973519A (en) * | 2020-09-11 | 2020-11-24 | 广州子芽生物科技有限公司 | Composition with repairing and anti-aging effects and application of composition in cosmetics |
| CN112029723A (en) * | 2020-09-18 | 2020-12-04 | 郑州佐爵生物科技有限公司 | Method for culturing umbilical cord blood CIK cells in vitro |
| CN112029723B (en) * | 2020-09-18 | 2021-08-06 | 陕西中港万海生命科学研究院有限公司 | Method for culturing umbilical cord blood CIK cells in vitro |
| CN112972284A (en) * | 2021-03-05 | 2021-06-18 | 山东科思达美生物科技有限公司 | Polypeptide composition for eye care and application |
| CN113576975A (en) * | 2021-08-25 | 2021-11-02 | 广州市雅创化妆品有限公司 | Easily-absorbed anti-aging composition and preparation method and application thereof |
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Application publication date: 20191206 |