CN115607476A - Composition with moisturizing and antioxidant effects and application thereof - Google Patents

Abstract

The invention relates to a composition with moisturizing and antioxidant effects and application thereof, wherein the composition with moisturizing and antioxidant effects comprises hydrolyzed elastin, fullerene, 3-o-ethyl ascorbic acid and ergothioneine. The invention creatively discovers that the composition consisting of the four components of the hydrolyzed elastin, the fullerene, the 3-o-ethyl ascorbic acid and the ergothioneine can interact with each other and positively influence each other, has unexpected synergistic promotion effect on moisture retention efficacy and antioxidant efficacy for technicians in the field, is very suitable for skin care products, is mild and non-irritant, and has good stability.

Description

Composition with moisturizing and antioxidant effects and application thereof

Technical Field

The invention belongs to the technical field of cosmetics, relates to a composition with moisturizing and antioxidant effects and application thereof, and particularly relates to a composition with moisturizing and antioxidant effects and application thereof in preparation of cosmetics.

Background

The skin is gradually aged due to the continuous contact with the outside, including external pollution, ultraviolet irradiation and other factors, which continuously generate free radicals. Free radicals are products of human cell metabolism, and excess free radicals have destructive effects on unsaturated fatty acids, protein molecules, nucleic acid molecules, extracellular soluble components, membrane lipids, etc., resulting in wrinkles, sagging, and decreased subcutaneous fat. The free radicals destroy collagen and elastic fiber protein, so as to make skin moisturize and maintain elasticity, and accelerate the precipitation of melanin. The increase in age and certain in vitro factors can cause the body and skin tissues to produce free radicals that exceed the body's normal ability to scavenge free radicals, causing damage to the skin tissues and resulting in aging.

Meanwhile, when the environment changes, the stratum corneum of the skin cannot timely regulate enough moisturizing factors, the activity of the sebaceous glands is reduced, the oil and water on the face are reduced, the skin is tightened, and fine wrinkles are even formed under the eyes and beside the canthus. Therefore, when skin is daily protected, the moisture of the skin needs to be kept, the loss of the moisture of the skin needs to be reduced, and a certain water-oil balance state of the skin needs to be maintained.

Moisture retention and oxidation resistance are important links for maintaining young skin and delaying aging, and development of a cosmetic product with effective moisture retention and oxidation resistance is very significant.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide a composition with moisturizing and antioxidant effects and application thereof, and particularly provides a composition with moisturizing and antioxidant effects and application thereof in preparation of cosmetics.

In order to achieve the purpose, the invention adopts the following technical scheme:

in a first aspect, the present invention provides a composition with moisturizing and antioxidant effects, which comprises hydrolyzed elastin, fullerene, 3-o-ethyl ascorbic acid and ergothioneine.

The invention creatively discovers that the composition consisting of the four components of the hydrolyzed elastin, the fullerene, the 3-o-ethyl ascorbic acid and the ergothioneine can interact with each other and positively influence each other, has unexpected synergistic promotion effect on moisture retention efficacy and antioxidant efficacy for technicians in the field, is very suitable for skin care products, is mild and non-irritant, and has good stability.

Preferably, the mass ratio of the hydrolyzed elastin, the fullerene, the 3-o-ethyl ascorbic acid and the ergothioneine in the composition with the moisturizing and anti-oxidation effects is (25000-35000): 1, (45000-55000): 200-300.

When the four components are combined in a specific mass ratio, the moisture-preserving effect and the antioxidant effect are more remarkably promoted mutually.

Preferably, the composition with moisturizing and antioxidant effects further comprises any one of or a combination of at least two of nicotinamide, dipotassium glycyrrhizinate, rice fermentation product filtrate, yeast amino acids, serum albumin, decarboxylated carnosine hydrochloride and mannitol.

Preferably, the composition with moisturizing and antioxidant effects further comprises a combination of nicotinamide, dipotassium glycyrrhizinate, rice fermentation product filtrate, yeast amino acids, serum albumin, decarboxylated carnosine hydrochloride and mannitol.

The composition further improves the efficacy in the aspects of moisture retention and oxidation resistance when the composition is added with the combination of nicotinamide, dipotassium glycyrrhizinate, rice fermentation product filtrate, yeast amino acids, serum albumin, decarboxylated carnosine hydrochloride and mannitol. Wherein the nicotinamide, the rice fermentation product filtrate and the mannitol have a certain synergistic effect in the aspect of improving the moisture retention of the composition; wherein the dipotassium glycyrrhizinate, the yeast amino acids, the serum albumin and the decarboxylated carnosine hydrochloride have certain synergistic effect on the aspect of improving the antioxidation of the composition.

Preferably, the composition with the moisturizing and antioxidant effects comprises 25000-35000 parts of hydrolyzed elastin, 1 part of fullerene, 45000-55000 parts of 3-o-ethyl ascorbic acid, 200-300 parts of ergothioneine, 200000-300000 parts of nicotinamide, 45000-55000 parts of dipotassium glycyrrhizinate, 200000-250000 parts of rice fermentation product filtrate, 20-30 parts of yeast amino acids, 1-10 parts of serum albumin, 400-600 parts of decarboxylated carnosine hydrochloride and 40000-55000 parts of mannitol by mass.

When the components are combined according to a specific mass ratio, the moisture-preserving effect and the antioxidant effect are mutually promoted more remarkably.

In a second aspect, the invention provides a composition with moisturizing and antioxidant effects according to the first aspect, and application of the composition in preparation of cosmetics.

Preferably, the composition with moisturizing and antioxidant effects accounts for 1-15% of the cosmetic by mass, such as 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, etc., and other specific values within the numerical range can be selected, which is not described in detail herein.

Preferably, the cosmetic comprises lotion, cream, essence, mask, makeup removing product and cleansing product.

In a third aspect, the invention provides an emulsion with moisturizing and antioxidant effects, which comprises the following components in percentage by mass: humectant, metal ion blocking agent, antioxidant, skin feeling regulator, emulsifier, emollient, skin conditioner, and water; the skin conditioner comprises the composition with moisturizing and antioxidant effects, which is disclosed in the first aspect.

Preferably, the emulsion with moisturizing and antioxidant effects comprises the following components in percentage by mass: 5-10% of humectant, 0.04-0.08% of metal ion blocking agent, 0.2-0.6% of antioxidant, 0.5-1% of skin feel regulator, 1-4% of emulsifier, 5-10% of emollient, 4-8% of skin conditioner and 70-80% of water.

The mass percentage of the humectant can be selected from 5%, 6%, 7%, 8%, 9%, 10% and the like; the mass percentage of the metal ion locking agent can be selected from 0.04%, 0.05%, 0.06%, 0.07%, 0.08% and the like; the mass percentage of the antioxidant can be selected from 0.2%, 0.3%, 0.4%, 0.5%, 0.6% and the like; the mass percentage of the skin feel regulator can be selected from 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1% and the like; the mass percentage of the emulsifier can be selected from 1%, 2%, 3%, 4% and the like; the mass percentage of the emollient can be selected from 5%, 6%, 7%, 8%, 9%, 10% and the like; the skin conditioner can be selected from 4%, 5%, 6%, 7%, 8% and the like in percentage by mass; the mass percentage of the water can be selected from 70%, 72%, 74%, 76%, 78%, 80% and the like. Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.

Preferably, the humectant comprises any one of glycerin, panthenol, sodium hyaluronate, butylene glycol, ethylhexylglycerin, or 1,2-hexanediol, or a combination of at least two of these.

Preferably, the skin feel modifier comprises any one of or a combination of at least two of sodium polyacryl dimethyl taurate, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, polyisobutylene, PEG-7 trimethylol propyl coco ether or sorbitan isostearate.

Preferably, the emulsifier comprises any one of or a combination of at least two of hydrogenated lecithin, a C14-22 alcohol, or a C12-20 alkyl glucoside.

Preferably, the emollient comprises any one or a combination of at least two of polydimethylsiloxane, squalane, jojoba oil, caprylic/capric triglyceride, shea butter or batyl alcohol.

Preferably, the skin conditioning agent further comprises polyvinylpyrrolidone.

Preferably, the metal ion blocking agent comprises disodium EDTA.

Preferably, the antioxidant comprises tocopherol acetate.

In a fourth aspect, the present invention provides a method for preparing the emulsion with moisturizing and antioxidant effects according to the third aspect, the method comprising:

(1) Adding water, humectant, metal ion blocking agent, and skin feeling regulator into water phase pot, stirring, heating and keeping temperature; adding emulsifier, emollient and antioxidant into the oil phase kettle, stirring, heating, and keeping the temperature;

(2) After the heat preservation is finished, pumping water and oil into an emulsifying pot, homogenizing, cooling, adding a skin conditioner, and stirring to obtain the skin conditioner;

preferably, the temperature of the homogenization is 75-85 ℃, such as 75 ℃, 77 ℃, 78 ℃, 80 ℃, 82 ℃, 84 ℃, 85 ℃ and the like; the homogenizing speed is 1000-3000rpm, such as 1000rpm, 1500rpm, 2000rpm, 2500rpm, 3000rpm, etc.

Preferably, the temperature reduction means temperature reduction to 40-50 ℃, such as 40 ℃, 42 ℃, 44 ℃, 45 ℃, 46 ℃, 47 ℃, 48 ℃, 49 ℃, 50 ℃ and the like.

Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.

Compared with the prior art, the invention has the following beneficial effects:

the invention creatively discovers that the composition consisting of the four components of the hydrolyzed elastin, the fullerene, the 3-o-ethyl ascorbic acid and the ergothioneine can interact with each other and positively influence each other, has unexpected synergistic promotion effect on moisture retention efficacy and antioxidant efficacy for technicians in the field, is very suitable for skin care products, is mild and non-irritant, and has good stability.

The composition of the invention further improves the efficacy in moisturizing and antioxidant aspects by adding a combination of nicotinamide, dipotassium glycyrrhizinate, rice fermentation product filtrate, yeast amino acids, serum albumin, decarboxylated carnosine hydrochloride and mannitol. Wherein, the nicotinamide, the rice fermentation product filtrate and the mannitol have a certain synergistic effect on the aspect of improving the moisture retention of the composition; wherein the dipotassium glycyrrhizinate, the yeast amino acids, the serum albumin and the decarboxylated carnosine hydrochloride have certain synergistic effect on the aspect of improving the antioxidation of the composition.

Detailed Description

In order to further illustrate the technical means and effects of the present invention, the technical solutions of the present invention are further described below with reference to the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.

The following examples, comparative examples, application examples and comparative application examples relate to products in which the source of the functional ingredients are as follows (only the functional ingredients are shown, and the necessary auxiliary ingredients contained in other commercially available raw materials are not described again):

hydrolyzed elastin is derived from a product available from i.r.a.istituto RICERCHE APPLICATE s.p.a. under the trade name MARINE ELASTIN PF;

the fullerenes are derived from a product available from Vitamin C60 Bioresearch Corporation under the trade name radial Sponge N (water-soluble plant fullerene);

the 3-o-ethyl ascorbic acid is derived from a product sold under the trade name 3-o-ethyl ascorbic acid available from Hubei Altaike Biotechnology, inc.;

ergothioneine is available from Shanghai Keqin science and technology Limited under the trade name of

-the product of Reyouth-5P;

niacinamide is available from DSM Nutritional Products ltd. Under the trade name Niacinamide PC;

the dipotassium glycyrrhizinate is obtained from a product sold under the trade name dipotassium glycyrrhizinate available from golden chemical Limited of Lanzhou;

the rice fermentation product filtrate is derived from a product of EX wine dreg extract MR which is purchased from Luojie biological science and technology limited company in Guangzhou city;

the yeast amino acids are from a product which is purchased from Guangzhou Kongdian Biotechnology Limited and has the trade name of oligopeptide composite stock solution;

the serum albumin is derived from a product which is purchased from Guangzhou Star(Biotech Co., ltd.) and is named oligopeptide composite stock solution;

the decarbonary carnosine hydrochloride salt was derived from a product available under the trade name ALISTIN SC from EXSYMOL s.a.m. company;

mannitol is available from Shanghai Keqin science and technology company, inc. under the trade name

-the product of Reyouth-5P;

polyvinylpyrrolidone is available from Vitamin C60 Bioresearch Corporation under the trade name radial Sponge N (water-soluble plant fullerene);

polyacryloyldimethyl taurate is derived from Aristoflex Silk, a product available from Clarian chemical technology (Shanghai) Co., ltd.

Example 1

The embodiment provides a composition with moisturizing and antioxidant effects, which comprises the following components in parts by weight: 30 parts of hydrolyzed elastin, 0.001 part of fullerene, 50 parts of 3-o-ethyl ascorbic acid and 0.3 part of ergothioneine.

Example 2

The embodiment provides a composition with moisturizing and antioxidant effects, which comprises the following components in parts by weight: 25 parts of hydrolyzed elastin, 0.001 part of fullerene, 55 parts of 3-o-ethyl ascorbic acid and 0.2 part of ergothioneine.

Example 3

The embodiment provides a composition with moisturizing and antioxidant effects, which comprises the following components in parts by weight: 35 parts of hydrolyzed elastin, 0.001 part of fullerene, 45 parts of 3-o-ethyl ascorbic acid and 0.3 part of ergothioneine.

Comparative example 1

This comparative example provides a composition which differs from example 1 only in that: contains no hydrolyzed elastin, and comprises the following components: 0.001 part of fullerene, 79.8 parts of 3-o-ethyl ascorbic acid and 0.5 part of ergothioneine.

Comparative example 2

This comparative example provides a composition which differs from example 1 only in that: contains no fullerene and comprises the following components: 30 parts of hydrolyzed elastin, 50 parts of 3-o-ethyl ascorbic acid and 0.3 part of ergothioneine.

Comparative example 3

This comparative example provides a composition which differs from example 1 only in that: 3-o-ethyl ascorbic acid is not contained, and comprises the following components: 79.5 parts of hydrolyzed elastin, 0.001 part of fullerene and 0.8 part of ergothioneine.

Comparative example 4

This comparative example provides a composition which differs from example 1 only in that: does not contain ergothioneine and comprises the following components: 30.1 parts of hydrolyzed elastin, 0.001 part of fullerene and 50.2 parts of 3-o-ethyl ascorbic acid.

Example 4

The embodiment provides a composition with moisturizing and antioxidant effects, which comprises the following components in parts by weight: 30 parts of hydrolyzed elastin, 0.001 part of fullerene, 50 parts of 3-o-ethyl ascorbic acid, 0.3 part of ergothioneine, 200 parts of nicotinamide, 50 parts of dipotassium glycyrrhizinate, 200 parts of rice fermentation product filtrate, 0.03 part of yeast amino acid, 0.01 part of serum albumin, 0.5 part of decarboxylated carnosine hydrochloride and 50 parts of mannitol.

Example 5

This example provides a composition with moisturizing and antioxidant effects, which differs from example 4 only in that: the fermented rice product does not contain nicotinamide, and the weight parts of the fermented rice product are proportionally distributed into the weight of the rice fermented product filtrate and the weight of the mannitol.

Example 6

This example provides a composition with moisturizing and antioxidant effects, which is different from example 4 only in that: the filtrate which does not contain the rice fermentation product is proportionally distributed into the weight of the nicotinamide and the mannitol.

Example 7

This example provides a composition with moisturizing and antioxidant effects, which differs from example 4 only in that: does not contain mannitol, and the weight parts of the mannitol are proportionally distributed into the weight of the filtrate of the nicotinamide and rice fermentation products.

Example 8

This example provides a composition with moisturizing and antioxidant effects, which differs from example 4 only in that: the yeast amino acids are not contained, and the weight parts of the yeast amino acids are proportionally distributed into the weight of serum albumin and decarboxylated carnosine hydrochloride.

Example 9

This example provides a composition with moisturizing and antioxidant effects, which is different from example 4 only in that: the yeast cell culture medium does not contain serum albumin, and the weight parts of the yeast cell culture medium are proportionally distributed to the weight of yeast amino acids and decarboxylated carnosine hydrochloride.

Example 10

This example provides a composition with moisturizing and antioxidant effects, which differs from example 4 only in that: the camosine hydrochloride does not contain decarboxylation carnosine hydrochloride, and the parts by weight of the camosine hydrochloride are proportionally distributed into the weights of the yeast amino acids and the serum albumin.

Application example 1

The application example provides an emulsion with moisturizing and antioxidant effects, and the formula of the emulsion is as follows:

the preparation method comprises the following steps:

(1) Adding water, humectant, metal ion blocking agent, and skin feeling regulator into water phase pot, stirring, heating to 85 deg.C, and keeping the temperature for 15min; adding emulsifier, emollient, and antioxidant into oil phase pan, stirring, heating to 80 deg.C, and keeping the temperature for 15min;

(2) After the heat preservation is finished, pumping water and oil into an emulsifying pot, homogenizing at 80 deg.C and 2000rpm for 2min, cooling to 45 deg.C, adding skin conditioner, and stirring for 15 min.

Application examples 2 to 7

The present application example provides seven kinds of emulsions having moisturizing and antioxidant effects, and the formulation thereof differs from application example 1 only in that the composition of example 4 is replaced with the same amount of the compositions of examples 5 to 10, respectively, and the other components and contents are maintained. Preparation method reference application example 1.

Comparative application example 1

The present application example provides an emulsion whose formulation differs from application example 1 only in that the composition of example 1 is removed, its content is made up with water, and the other ingredients and contents remain unchanged. Preparation method reference application example 1.

Test example 1

In vitro antioxidant performance test:

experimental apparatus and reagents:

the main apparatus is as follows: spectrophotometer SpectronicGENESSYS-5, thermo corporation, USA.

The main reagents are as follows: DPPH, analytically pure, tianjin majo; methanol, analytically pure, tianjin maozhi; ascorbic acid, analytically pure, shanghai national drug.

Solution preparation: firstly, 1mg of DPPH is dissolved in about 20mL of methanol, ultrasonic treatment is carried out for 5min, and the mixture is fully shaken to ensure that the upper part and the lower part are uniform. Taking 1mL of the DPPH solution, and measuring the A value at 519nm to ensure that A = 1.2-1.3; preparing each sample solution: the compositions of examples 1 to 11 and comparative examples 1 to 4 were diluted with methanol to prepare a composition having a mass fraction of 1%.

The specific method comprises the following steps: each set of sample adding system is shown in the following table, the reaction solution is shaken up and placed in a water bath at 37 ℃ for heating for 15min, and then taken out, and an ultraviolet-visible spectrophotometer is used for measuring the absorbance value of the solution.

Reagent	C1/mL	C2/mL	C3/mL
				DPPH solution	2	2	0
Sample solution	0	2	2
				Anhydrous methanol	2	0	2

The formula for the DPPH radical clearance is shown as follows:

DPPH radical clearance =1- (A2-A3)/A1 × 100%

In the formula, A1, A2 and A3 are absorbance values of C1, C2 and C3 respectively.

The test results are shown in table 1:

TABLE 1

Group of	DPPH radical scavenging ratio (%)
		Example 1	76.2
Example 2	74.7
		Example 3	76.6
Example 4	87.4
		Example 5	86.9
Example 6	87.6
		Example 7	86.3
Example 8	82.9
		Example 9	82.5
Example 10	80.8
		Comparative example 1	74.1
Comparative example 2	65.3
		Comparative example 3	73.3
Comparative example 4	70.8

As can be seen from the data in Table 1: the overall DPPH radical scavenging rate of examples 1-3 is higher than that of comparative examples 1-4, indicating that the DPPH radical scavenging effect is reduced in the absence of either component of the composition; the DPPH free radical scavenging rate of example 4 is higher than that of examples 8-10, which shows that yeast amino acids, serum albumin and decarboxylated carnosine hydrochloride also have a certain synergistic effect on DPPH free radical scavenging effect.

Test example 2

And (3) comprehensive effect experiment of moisturizing and antioxidation:

(1) 80 Chinese healthy female subjects with dark, dark yellow and uneven facial skin are selected, the age range is 25-60 years old, and the average age is 46.3 +/-5.6 years old. Stratum corneum water content, skin elasticity measurements (curometer) facial image capture (VISIA-CR, VC20 Plus), facial image analysis (VC 20 Plus) analysis of skin wrinkles were tested on the skin before (D0) and after 4 weeks with the test product (D28).

(2) The test products are emulsion products prepared in application examples 1-7 and comparative application example 1; the test environment is at a temperature of 20 +/-2 ℃ and a humidity of 50 +/-5%, and meets the requirements of scheme design; promotion/improvement after use of the product (%) = (data after use-data before use)/data before use × 100%.

(3) The comparison statistics of the moisture content of the face stratum corneum (C.U), the comparison results before and after the use of the elasticity R2 value of the cheek skin, and the comparison results before and after the use of the statutory print SEw are shown in Table 2:

TABLE 2

As can be seen from the data in Table 2: the overall moisturizing effect and anti-aging effect of application examples 1-7 are higher than that of comparative application example 1, which shows that the composition of the present invention has significant moisturizing and anti-oxidation effects, wherein the comprehensive effect of application example 1 is better.

Test example 3

Skin irritation test:

skin irritation measurements were performed using the emulsions of application examples 1-7. 35 women were selected as the test subjects, the spot test tapes containing 0.03mL of the samples were applied to the normal skin of the left forearm of the test subjects, and the test was conducted 6 times within a half hour after the application of the patch according to the CTFA guidelines (1981), and on the 6 th day after the application of the patch, additional tests were conducted to observe delayed reactions, and the identification criteria and results are shown in Table 3 and Table 4, respectively.

TABLE 3

Grade	(symbol)	Identification criteria
			0	-	Negative reaction: has no irritation and erythema
1	±	And (3) suspicious reaction: mild erythema
			2	+	Weak positive reaction: erythema
3	++	Strong positive reaction: erythema, papules, blisters
			4	+++	Very positive reaction: severe edema and bulla

TABLE 4

From the above data results, it can be seen that: the composition and the emulsion have no stimulation to skin, have no positive reaction and have mild and non-stimulation effects.

The applicant states that the present invention is illustrated by the above examples to show a composition with moisturizing and antioxidant effects and its application, but the present invention is not limited to the above examples, i.e. it does not mean that the present invention must be implemented by the above examples. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.

The preferred embodiments of the present invention have been described in detail, however, the present invention is not limited to the specific details of the above embodiments, and various simple modifications may be made to the technical solution of the present invention within the technical idea of the present invention, and these simple modifications are within the protective scope of the present invention.

It should be noted that the various technical features described in the above embodiments can be combined in any suitable manner without contradiction, and the invention is not described in any way for the possible combinations in order to avoid unnecessary repetition.

Claims (10)

1. A composition with moisturizing and antioxidant effects is characterized by comprising hydrolyzed elastin, fullerene, 3-o-ethyl ascorbic acid and ergothioneine.

2. The composition with moisturizing and antioxidant effects as claimed in claim 1, wherein the mass ratio of hydrolyzed elastin, fullerene, 3-o-ethyl ascorbic acid and ergothioneine in the composition with moisturizing and antioxidant effects is (25000-35000): 1 (45000-55000): 200-300.

3. The composition with moisturizing and antioxidant effects as claimed in claim 1 or 2, wherein the composition with moisturizing and antioxidant effects further comprises any one or a combination of at least two of nicotinamide, dipotassium glycyrrhizinate, rice fermentation product filtrate, yeast amino acids, serum albumin, decarboxylated carnosine hydrochloride or mannitol;

preferably, the composition with moisturizing and antioxidant effects further comprises a combination of nicotinamide, dipotassium glycyrrhizinate, rice fermentation product filtrate, yeast amino acids, serum albumin, decarboxypeptide hydrochloride and mannitol.

4. The composition with moisturizing and antioxidant effects as claimed in any one of claims 1-3, wherein the composition with moisturizing and antioxidant effects comprises 25000-35000 parts of hydrolyzed elastin, 1 part of fullerene, 45000-55000 parts of 3-o-ethyl ascorbic acid, 200-300 parts of ergothioneine, 200000-300000 parts of nicotinamide, 45000-55000 parts of dipotassium glycyrrhizinate, 200000-250000 parts of rice fermentation product filtrate, 20-30 parts of yeast amino acids, 1-10 parts of serum albumin, 400-600 parts of decarboxylated carnosine hydrochloride and 40000-55000 parts of mannitol by mass.

5. Use of the composition with moisturizing and antioxidant effects according to any one of claims 1-4 in the preparation of cosmetics.

6. The use of claim 5, wherein the composition with the moisturizing and antioxidant effects accounts for 1-15% of the weight of the cosmetic;

preferably, the cosmetic comprises lotion, cream, essence, mask, makeup removing product and cleansing product.

7. The emulsion with the moisturizing and antioxidant effects is characterized by comprising the following components in percentage by mass: humectant, metal ion blocking agent, antioxidant, skin feeling regulator, emulsifier, emollient, skin conditioner, and water; the skin conditioner comprises the composition with moisturizing and antioxidant effects as claimed in any one of claims 1 to 4.

8. The emulsion with moisturizing and antioxidant effects as claimed in claim 7, wherein the emulsion with moisturizing and antioxidant effects comprises, by mass: 5-10% of humectant, 0.04-0.08% of metal ion locking agent, 0.2-0.6% of antioxidant, 0.5-1% of skin feel regulator, 1-4% of emulsifier, 5-10% of emollient, 4-8% of skin conditioner and 70-80% of water.

9. The emulsion with moisturizing and antioxidant effects as claimed in claim 7 or 8, wherein the moisturizer comprises any one of glycerin, panthenol, sodium hyaluronate, butylene glycol, ethylhexyl glycerin or 1,2-hexanediol or a combination of at least two of them;

preferably, the skin feel modifier comprises any one of or a combination of at least two of sodium polyacryl dimethyl taurate, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, polyisobutylene, PEG-7 trimethylol propyl coco ether or sorbitan isostearate;

preferably, the emulsifier comprises any one of or a combination of at least two of hydrogenated lecithin, a C14-22 alcohol, or a C12-20 alkyl glucoside;

preferably, the emollient comprises any one or combination of at least two of polydimethylsiloxane, squalane, jojoba seed oil, caprylic/capric triglyceride, shea butter or batyl alcohol;

preferably, the skin conditioning agent further comprises polyvinylpyrrolidone;

preferably, the metal ion blocking agent comprises disodium EDTA;

preferably, the antioxidant comprises tocopherol acetate.

10. The method for preparing the emulsion with moisturizing and antioxidant effects according to any one of claims 7-9, wherein the method for preparing the emulsion comprises the following steps:

(1) Adding water, humectant, metal ion blocking agent, and skin feeling regulator into water phase pot, stirring, heating and keeping temperature; adding emulsifier, emollient and antioxidant into oil phase pan, stirring, heating and keeping temperature;

(2) After the heat preservation is finished, pumping water and oil into an emulsifying pot, homogenizing, cooling, adding a skin conditioner, and stirring to obtain the skin conditioner;

preferably, the temperature of homogenization is 75-85 ℃; the homogenizing rotating speed is 1000-3000rpm;

preferably, the temperature reduction refers to temperature reduction to 40-50 ℃.