CN116509750A - Composite fish collagen mask liquid and preparation method thereof - Google Patents
Composite fish collagen mask liquid and preparation method thereof Download PDFInfo
- Publication number
- CN116509750A CN116509750A CN202310652949.9A CN202310652949A CN116509750A CN 116509750 A CN116509750 A CN 116509750A CN 202310652949 A CN202310652949 A CN 202310652949A CN 116509750 A CN116509750 A CN 116509750A
- Authority
- CN
- China
- Prior art keywords
- parts
- raw materials
- preparation
- mask liquid
- collagen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000008186 Collagen Human genes 0.000 title claims abstract description 49
- 108010035532 Collagen Proteins 0.000 title claims abstract description 49
- 229920001436 collagen Polymers 0.000 title claims abstract description 49
- 241000251468 Actinopterygii Species 0.000 title claims abstract description 36
- 239000007788 liquid Substances 0.000 title claims abstract description 26
- 239000002131 composite material Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 239000002994 raw material Substances 0.000 claims abstract description 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 28
- 229920001661 Chitosan Polymers 0.000 claims abstract description 18
- 239000002537 cosmetic Substances 0.000 claims abstract description 7
- 238000005868 electrolysis reaction Methods 0.000 claims abstract description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 24
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000008367 deionised water Substances 0.000 claims description 13
- 229910021641 deionized water Inorganic materials 0.000 claims description 13
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 13
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 13
- XMWRBQBLMFGWIX-UHFFFAOYSA-N C60 fullerene Chemical compound C12=C3C(C4=C56)=C7C8=C5C5=C9C%10=C6C6=C4C1=C1C4=C6C6=C%10C%10=C9C9=C%11C5=C8C5=C8C7=C3C3=C7C2=C1C1=C2C4=C6C4=C%10C6=C9C9=C%11C5=C5C8=C3C3=C7C1=C1C2=C4C6=C2C9=C5C3=C12 XMWRBQBLMFGWIX-UHFFFAOYSA-N 0.000 claims description 12
- 230000003712 anti-aging effect Effects 0.000 claims description 12
- 229910003472 fullerene Inorganic materials 0.000 claims description 12
- 239000002904 solvent Substances 0.000 claims description 11
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 10
- 229920002125 Sokalan® Polymers 0.000 claims description 10
- 229960001631 carbomer Drugs 0.000 claims description 10
- 235000011187 glycerol Nutrition 0.000 claims description 10
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 10
- 229960003415 propylparaben Drugs 0.000 claims description 10
- 229940032094 squalane Drugs 0.000 claims description 10
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 8
- 239000000686 essence Substances 0.000 claims description 8
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 8
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 229920002101 Chitin Polymers 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 241000276707 Tilapia Species 0.000 claims description 3
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims description 3
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims description 3
- 229960002216 methylparaben Drugs 0.000 claims description 3
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims description 3
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 claims description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 2
- 229940124277 aminobutyric acid Drugs 0.000 claims description 2
- 239000004359 castor oil Substances 0.000 claims description 2
- 235000019438 castor oil Nutrition 0.000 claims description 2
- 238000007796 conventional method Methods 0.000 claims description 2
- 238000001816 cooling Methods 0.000 claims description 2
- 230000006196 deacetylation Effects 0.000 claims description 2
- 238000003381 deacetylation reaction Methods 0.000 claims description 2
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 2
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical group NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 2
- 229920002674 hyaluronan Polymers 0.000 claims description 2
- 229960003160 hyaluronic acid Drugs 0.000 claims description 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims description 2
- 235000019799 monosodium phosphate Nutrition 0.000 claims description 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical group [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims description 2
- BAPRUDZDYCKSOQ-RITPCOANSA-N (2s,4r)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid Chemical compound CC(=O)N1C[C@H](O)C[C@H]1C(O)=O BAPRUDZDYCKSOQ-RITPCOANSA-N 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 238000001223 reverse osmosis Methods 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract description 8
- 206010000496 acne Diseases 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 8
- 230000002087 whitening effect Effects 0.000 abstract description 6
- 230000003020 moisturizing effect Effects 0.000 abstract description 5
- 230000008439 repair process Effects 0.000 abstract description 5
- 230000032683 aging Effects 0.000 abstract description 2
- 230000007794 irritation Effects 0.000 abstract description 2
- 229930014626 natural product Natural products 0.000 abstract description 2
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 43
- 108090000765 processed proteins & peptides Proteins 0.000 description 11
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- 206010008570 Chloasma Diseases 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- 208000003351 Melanosis Diseases 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 125000000539 amino acid group Chemical group 0.000 description 1
- -1 artificial tissues Substances 0.000 description 1
- 210000000270 basal cell Anatomy 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 230000003511 endothelial effect Effects 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 230000007760 free radical scavenging Effects 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002591 hydroxyproline Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 231100001083 no cytotoxicity Toxicity 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000036620 skin dryness Effects 0.000 description 1
- 238000009283 thermal hydrolysis Methods 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/83—Electrophoresis; Electrodes; Electrolytic phenomena
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a composite fish collagen mask liquid and a preparation method thereof. The chitosan is produced by taking fish scales as raw materials in an electrochemical water electrolysis mode, and is applied to the field of cosmetics. The special effects of fish collagen and conopeptide are applied to improve the skin color and repair various acne marks and pits. The functional raw materials of the product are all natural products, the raw materials are nontoxic and harmless, the biocompatibility is excellent, the irritation is small, and the functions of various raw materials are integrated to achieve the effects of whitening, moisturizing and resisting aging.
Description
Technical Field
The invention relates to the field of cosmetics, and relates to a dressing mask produced by using collagen and collagen peptide and a preparation method thereof.
Background
With the rapid improvement of national life quality, people pay more attention to skin care. One of the important aspects in skin care is moisturizing and the other is anti-aging repair. The skin contains a large amount of water, and scientific researches show that the water content of the skin cuticle is about 15-30% in general. These moisture have an indispensable role in the functional activities of the human body, and the moisture content of the skin can be used to confirm the youth of a person. Therefore, the skin of the user looks like water to be smooth, soft and tender and is full of elasticity, and the skin is also a common pursuit of all lovers.
Although our skin can lock in moisture, its ability is limited after all, and it is difficult to maintain a youthful skin condition if the water replenishment and protection are not noticed in the afternoon. At present, people are trapped in working and living pressure, most of people are in sub-health state, and the water and oil imbalance and skin dryness of human skin can be caused by factors such as age, seasonal change, living environment and the like. Skin is tight, dark yellow, dry and peeled in individual parts, and skin itch or inflammation is also caused when severe. Thereby causing skin to grow acne, and the acne marks further deteriorate the aesthetic feeling of the skin.
In order to solve the problem of dryness and lack of moisture of skin, a moisturizing factor is often added into cosmetics in skin care to achieve the aim. The chitosan is a product of deacetylation of natural chitin, and has no endothelial irritation, no cytotoxicity, good biological safety, biodegradability and biocompatibility, and whitening and moisturizing properties because the chitosan is a natural product. Thereby being widely applied to the fields of food, medical treatment, cosmetics, artificial tissues, medicine slow release carriers and the like.
In order to solve the problem of skin dark yellow pigmentation, functional ingredients are often added into cosmetics in skin care to achieve the purpose of whitening. Through researches, the color spots are mainly formed by active oxygen species "
(active oxygen) initiation. When active oxygen generated on the skin is exposed to ultraviolet rays and contacts a large amount of ultraviolet rays, melanin (melanocytes) is extremely activated, thereby causing stains. Fullerene has strong oxidation resistance and high whitening capability constructed by free radical scavenging functions, and can effectively prevent color spots from being generated.
In order to repair the problems of inflammation and acne marks present in the skin, we often add anti-ageing and repairing components to the cosmetics in skin care. "collagen" is also called collagen, and is the protein with the largest content in the human body, and accounts for about 30-40% of the total amount of the protein in the human body. Collagen is an important functional polysaccharide protein that is widely distributed in the soft and hard connective tissues of organisms, and together with elastin and keratin, constitutes the extracellular skeleton, also known as the "scaffold of life". The collagen peptide is a functional peptide which has a triple-helix structure and consists of a short sequence of 2-20 amino acid residues after enzymolysis and thermal hydrolysis treatment of collagen. Collagen peptide is composed of three peptide chains, each of which contains a repeating sequence of (Gly-X-Y), X and Y being proline and hydroxyproline, respectively.
Collagen and peptide thereof have rich functions, and can supplement skin nutrition. The collagen peptide is a small molecular active peptide, has higher permeability, can be well absorbed and utilized by human skin tissues, supplements the nutrition components required by the skin, ensures that the skin becomes more moist and smooth, and can also increase the elasticity and tension of the skin. Second, remove skin wrinkles and delay aging. After the collagen peptide is used, division of epidermal basal cells can be promoted, the epidermal cells can be enabled to be younger, the effect of reducing wrinkles is achieved, the skin can be enabled to be more compact and elastic, and the problem of skin aging is solved. Thirdly, the skin-whitening cream can supplement water, moisturize and whiten skin. The collagen peptide can better inject a certain amount of water molecules into skin tissues, can strengthen the metabolism function of the skin, relieve the dryness of the skin, inhibit and reduce the formation of melanin, relieve chloasma or sunburn appearing on the face, and play a role in whitening the skin. Fourth, repair damaged skin. The collagen peptide has good effect on repairing damaged skin tissues and has certain effect on eliminating acne pits and acne marks.
Disclosure of Invention
The invention aims to solve various problems of skin, and provides a composite fish collagen mask liquid and a preparation method thereof, wherein chitosan raw materials are prepared by an electrochemical water electrolysis method.
In order to achieve the above object, the present invention provides the following technical solutions: the composite fish collagen mask liquid is characterized by comprising functional raw materials and auxiliary raw materials, wherein the functional raw materials comprise the following raw materials in parts by weight: 5-10 parts of fish skin collagen, 3-7 parts of conopeptide, 3-7 parts of fullerene and 1-3 parts of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 2-5 parts of sodium hyaluronate, 3-5 parts of chitosan, 3-5 parts of squalane, 6-10 parts of glycerol, 1-5 parts of carbomer, 0.1-0.3 part of methyl hydroxybenzoate, 0.1-0.2 part of propyl hydroxybenzoate, 0.01-0.05 part of essence, 0.2-0.5 part of solubilizer, a proper amount of ph regulator and deionized water are added into 1000.
The preferred functional raw materials comprise the following raw materials in parts by weight: 5 parts of fish skin collagen,
3 parts of conopeptide, 4 parts of fullerene and 2 parts of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 3 parts of sodium hyaluronate, 3 parts of chitosan, 3 parts of squalane, 10 parts of glycerin, 4 parts of carbomer, 0.1 part of methylparaben, 0.2 part of propylparaben, 0.01 part of essence, 0.5 part of solubilizer, a proper amount of ph regulator and deionized water are added into 1000.
The preferred anti-aging ingredients are aminobutyric acid and acetohydroxyproline compositions.
A preferred solubilising agent is PEG-40 hydrogenated castor oil.
Preferred ph modifiers are sodium dihydrogen phosphate and disodium hydrogen phosphate compositions.
The preferred flavour is rose flavour.
A composite fish collagen mask liquid and a preparation method thereof are characterized by comprising the following steps:
production of chitin and production of chitosan according to electrochemical water electrolysis method
Collagen is obtained from tilapia skin according to a conventional method
Sequentially adding chitosan, hyaluronic acid, fullerene, squalane and a certain amount of deionized water according to the sequence, and heating to 70 ℃ in the stirring process. The mixture is mixed for 10 minutes at 70 ℃ to obtain the functional liquid.
Adding glycerol, carbomer, methyl hydroxybenzoate, propyl hydroxybenzoate, essence, solubilizer, and deionized water into another container, and stirring. Heating to 70 ℃ in the process, and mixing at 70 ℃ for 10 minutes to obtain auxiliary liquid.
Mixing the two container liquids, cooling to 45 ℃, adding fish collagen and conopeptide, and adding a ph regulator to regulate ph to 6. Homogenizing in a homogenizer to obtain the product.
The invention has the following effects: the invention adopts natural fish extract, which gives consideration to moisturizing, whitening and repairing. The addition of the fullerene can inhibit and reduce the formation of melanin, has the effects of strong oxidizing capacity and free radical removal, takes effect together with the conopeptide and the collagen, has obvious effect on skin repair, and can eliminate acne marks and acne pits after long-term use.
Detailed Description
Embodiment one: a composite fish collagen mask liquid and a preparation method thereof are characterized in that,
the functional raw materials comprise the following raw materials in parts by weight: 5 g of fish skin collagen, 3 g of conopeptide, 4 g of fullerene and 2 g of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 3 g of sodium hyaluronate, 3 g of chitosan, 3 g of squalane, 10 g of glycerin, 4 g of carbomer, 0.1 g of methyl hydroxybenzoate, 0.2 g of propyl hydroxybenzoate, 0.01 g of essence, 0.5 g of solubilizer,
proper amount of ph regulator, deionized water was added to 1000 grams.
Embodiment two: a composite fish collagen mask liquid and a preparation method thereof are characterized in that,
the functional raw materials comprise the following raw materials in parts by weight: 6 g of fish skin collagen, 4 g of conopeptide, 4 g of fullerene and 3 g of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 3 g of sodium hyaluronate, 4 g of chitosan, 5 g of squalane, 8 g of glycerin, 3 g of carbomer, 0.2 g of methyl hydroxybenzoate, 0.2 g of propyl hydroxybenzoate, 0.02 g of essence, 0.5 g of solubilizer and ph
Proper amount of regulator, deionized water was added to 1000 g.
Embodiment III: a composite fish collagen mask liquid and a preparation method thereof are characterized in that,
the functional raw materials comprise the following raw materials in parts by weight: 10 g of fish skin collagen, 4 g of conopeptide, 5 g of fullerene and 3 g of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 5 g of sodium hyaluronate, 2 g of chitosan, 2 g of squalane, 6 g of glycerin, 4 g of carbomer, 0.1 g of methyl hydroxybenzoate, 0.2 g of propyl hydroxybenzoate, 0.01 g of essence, 0.5 g of solubilizer and ph
Proper amount of regulator, deionized water was added to 1000 g.
Embodiment four: a composite fish collagen mask liquid and a preparation method thereof are characterized in that,
the functional raw materials comprise the following raw materials in parts by weight: 7 g of fish skin collagen, 5 g of conopeptide, 5 g of fullerene and 3 g of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 5 g of sodium hyaluronate, 4 g of chitosan, 6 g of squalane, 8 g of glycerin, 2 g of carbomer, 0.1 g of methyl paraben, 0.2 g of propyl paraben, 0.01 g of essence, 0.5 g of solubilizer, a proper amount of ph regulator and 1000 g of deionized water.
Claims (10)
1. The composite fish collagen mask liquid is characterized by comprising functional raw materials and auxiliary raw materials, wherein the functional raw materials comprise the following raw materials in parts by weight: 5-10 parts of fish skin collagen, 3-7 parts of conopeptide, 3-7 parts of fullerene and 1-3 parts of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 2-5 parts of sodium hyaluronate, 3-5 parts of chitosan, 3-5 parts of squalane, 6-10 parts of glycerol, 1-5 parts of carbomer, 0.1-0.3 part of methyl hydroxybenzoate, 0.1-0.2 part of propyl hydroxybenzoate, 0.01-0.05 part of essence, 0.2-0.5 part of solubilizer, a proper amount of ph regulator and deionized water are added into 1000.
2. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the functional raw materials comprise the following raw materials in parts by weight: 5 parts of fish skin collagen, 3 parts of conopeptide, 4 parts of fullerene and 2 parts of anti-aging component. The auxiliary raw materials comprise the following raw materials in parts by weight: 3 parts of sodium hyaluronate, 3 parts of chitosan, 3 parts of squalane, 10 parts of glycerin, 4 parts of carbomer, 0.1 part of methylparaben, 0.2 part of propylparaben, 0.01 part of essence, 0.5 part of solubilizer, a proper amount of ph regulator and 1000 parts of deionized water.
3. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the fish skin collagen is extracted from tilapia skin.
4. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the chitosan raw material is fish scales and chitosan is obtained by deacetylation of chitin produced by electrochemical electrolysis of water.
5. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the anti-aging component is a composition of aminobutyric acid and acetylhydroxyproline in a ratio of 1:1.
6. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the dressing cosmetic containing fish collagen and conopeptide is in the form of a mask dressing product.
7. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the solubilizing agent is PEG-40 hydrogenated castor oil.
8. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the ph regulator is a composition of sodium dihydrogen phosphate and disodium hydrogen phosphate.
9. The composite fish collagen mask liquid and the preparation method thereof according to claim 1, wherein the water is deionized water, the conductivity of the water is greater than 5mΩ -cm, and the water is obtained by a reverse osmosis purification method.
10. The composite fish collagen mask liquid and the preparation method thereof according to claims 1-9 are characterized by comprising the following steps:
1) Production of chitin and production of chitosan according to electrochemical water electrolysis method
2) Collagen is obtained from tilapia skin according to a conventional method
3) Sequentially adding chitosan, hyaluronic acid, fullerene, squalane and a certain amount of deionized water according to the sequence, and heating to 70 ℃ in the stirring process.
The mixture is mixed for 10 minutes at 70 ℃ to obtain the functional liquid.
4) Adding glycerol, carbomer, methyl hydroxybenzoate, propyl hydroxybenzoate, essence, solubilizer, and deionized water into another container, and stirring. Heating to 70 ℃ in the process, and mixing at 70 ℃ for 10 minutes to obtain auxiliary liquid.
5) Mixing the two container liquids, cooling to 45 ℃, adding fish collagen and conopeptide, and adding a ph regulator to regulate ph to 6. Homogenizing in a homogenizer to obtain the product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310652949.9A CN116509750A (en) | 2023-06-05 | 2023-06-05 | Composite fish collagen mask liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310652949.9A CN116509750A (en) | 2023-06-05 | 2023-06-05 | Composite fish collagen mask liquid and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116509750A true CN116509750A (en) | 2023-08-01 |
Family
ID=87403089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310652949.9A Pending CN116509750A (en) | 2023-06-05 | 2023-06-05 | Composite fish collagen mask liquid and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116509750A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117323807A (en) * | 2023-12-01 | 2024-01-02 | 吉林大学 | Deodorant containing microgel and preparation method thereof |
-
2023
- 2023-06-05 CN CN202310652949.9A patent/CN116509750A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117323807A (en) * | 2023-12-01 | 2024-01-02 | 吉林大学 | Deodorant containing microgel and preparation method thereof |
| CN117323807B (en) * | 2023-12-01 | 2024-01-23 | 吉林大学 | Deodorant containing microgel and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109620748B (en) | Anti-wrinkle essence and preparation method thereof | |
| CN111686029A (en) | Anti-aging wrinkle-removing composition | |
| CN104856892A (en) | Cosmetic or skin care product preparation rich in growth factors and preparation method therefor | |
| CN113616566B (en) | Skin care essence for tightening skin and preparation method thereof | |
| KR20040006007A (en) | Acidic composition for external use and agent for accelerating infiltration of cosmetic preparation, hair-growing agent, and preparation for external use each containing the composition into skin or the like | |
| CN106727148A (en) | Facial mask and preparation method thereof is repaired in a kind of dendrobium candidum moisturizing | |
| CN109549863A (en) | A kind of lightening compositions and preparation method thereof | |
| CN110123729A (en) | A kind of jelly film and preparation method thereof | |
| CN111450010A (en) | Composition with anti-aging effect and application thereof in cosmetics | |
| CN108272693A (en) | Whitening spot-eliminating composition and preparation method thereof | |
| CN113576975A (en) | Easily-absorbed anti-aging composition and preparation method and application thereof | |
| CN110721148A (en) | Multidirectional pulling and tightening polypeptide essence and preparation method thereof | |
| CN116509750A (en) | Composite fish collagen mask liquid and preparation method thereof | |
| CN104490713A (en) | Super-soft living spring skin care product with functions of removing foul, tightening, resisting wrinkles and activating skin | |
| KR20220114509A (en) | Cleansing agent composition and cleanser prepared thereby | |
| CN108309817A (en) | A kind of whitening mask Essence and preparation method thereof using resveratrol | |
| CN113768853B (en) | Whitening and freckle-removing composition, and preparation method and application thereof | |
| CN110840782A (en) | Face-refreshing and skin-cleaning facial mask composition and preparation method thereof | |
| CN113633575A (en) | Skin color brightening composition and preparation method of essence thereof | |
| JP2001131049A (en) | Skin preparation for external use | |
| CN113332196A (en) | Green tea polyphenol repair gel for deep skin repair and preparation method thereof | |
| CN111166707B (en) | Facial anti-aging repairing and nursing composition and preparation method and application thereof | |
| CN111759762A (en) | Black eye removing composition, essence and preparation method thereof | |
| CN115444766A (en) | Double-component shampoo with scalp nourishing effect and preparation method thereof | |
| CN108392444A (en) | Micro- whole all-round aquation cosmetic of one kind and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |