CN115444766A

CN115444766A - Double-component shampoo with scalp nourishing effect and preparation method thereof

Info

Publication number: CN115444766A
Application number: CN202211287750.2A
Authority: CN
Inventors: 段东平; 李婷; 任玉枝; 黄伟文; 杨天云; 梁结时
Original assignee: Guangxi Hegui Group Co ltd; Institute of Process Engineering of CAS
Current assignee: Guangxi Hegui Group Co ltd; Institute of Process Engineering of CAS
Priority date: 2022-02-17
Filing date: 2022-10-20
Publication date: 2022-12-09
Anticipated expiration: 2042-10-20
Also published as: CN115444766B

Abstract

The invention relates to a double-component shampoo with scalp nourishing effect and a preparation method thereof, wherein the double-component shampoo with scalp nourishing effect comprises a first component and a second component; the first component comprises a surfactant, a foam booster, a conditioning agent, a thickening agent, a lubricant, a preservative, a pH regulator and water; the second component comprises a humectant, a conditioner and water; the conditioning agent in the second component comprises a strontium containing compound. The invention creatively adds the strontium-containing compound into the shampoo product, utilizes the bioactivity of strontium element such as promoting collagen formation, inducing angiogenesis, promoting cell endothelial proliferation and the like to keep scalp vitality, nourish hair follicles, maintain the basic environment for hair growth, and further grow stronger and healthy hair, and strontium enters human body through the scalp to play a role in supplementing trace elements.

Description

Bi-component shampoo with scalp nourishing effect and preparation method thereof

Technical Field

The invention belongs to the technical field of daily chemical products, and particularly relates to a bi-component shampoo with scalp nourishing effect and a preparation method thereof.

Background

The condition of a person's hair often reflects much information about the person, such as health status, mental state, mood, lifestyle habits, etc., so people are also increasingly paying more attention to the hair care of the person. The shampoo is a hair washing and protecting product which is used most frequently in daily life of people, and mainly has the function of cleaning scalp and hair. Most of the shampoo in the current market only has a single cleaning function, has no effect of caring hair and scalp, and cannot fundamentally promote the health of the scalp and the hair. On the other hand, in order to pursue more hair growth and hair loss prevention, some shampoo products are added with a large amount of amine components and surfactants, and even some solid medical components, and most of the additives are difficult to dissolve in water, so that the emulsified system of the shampoo is unstable, the appearance and the using hand feeling of the shampoo are influenced, and even the functionality of the shampoo is difficult to fully exert.

CN110496084A discloses a scalp injury repairing cleansing shampoo which is prepared from the following raw materials in percentage by mass: 5-10% of cocoyl sodium glutamate, 5-10% of sodium lauryl glucose carboxylate, 2-5% of sodium cocoyl glycinate, 5-10% of cocamidopropyl betaine, 2-5% of myristyl glucoside, 2-5% of sodium lauroyl sarcosinate, 2-8% of soapberry extract, 1-5% of common andrographis herb extract, 1-5% of honeysuckle extract, 1-5% of coptis chinensis extract, 5-10% of glycerol and the balance of deionized water.

CN109864913A discloses a ginkgo leaf shampoo and a preparation method thereof. The shampoo comprises silicone oil and folium Ginkgo extract, and also comprises one or more of folium Platycladi extract, rhizoma Zingiberis recens extract, folium Artemisiae Argyi extract, and Ginseng radix extract. The ginkgo leaf extract extracted by ultrasonic wave is used as an active component of the shampoo, and can remove free radicals on the surface of scalp, remove dandruff, nourish scalp cells, promote the deposition of silicone oil on the surface of hair, and enable the cleaned hair to be rich in luster, black and bright.

Active nourishing components in the shampoo products disclosed in the prior art are traditional Chinese medicine plant extracts, plant essential oil, protein amino acid and the like, but most of the components are macromolecular substances and can be really absorbed by skin cells to play a practical role.

Therefore, it is very significant to develop a shampoo product which is easily absorbed by the scalp, has safe components, and has the effects of maintaining and cleaning the scalp and maintaining and cleaning the hair.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide a bi-component shampoo with scalp nourishing efficacy and a preparation method thereof.

In order to achieve the purpose, the invention adopts the following technical scheme:

in a first aspect, the invention provides a two-component shampoo with scalp nourishing efficacy, which comprises a first component and a second component;

the first component comprises a surfactant, a foam booster, a conditioning agent, a thickening agent, a lubricant, a preservative, a pH regulator and water; the second component comprises a humectant, a conditioner and water;

the conditioning agent in the second component comprises a strontium containing compound; the strontium-containing compound comprises any one of strontium chloride, strontium chloride hexahydrate, strontium hydroxide, strontium acetate, strontium citrate, strontium gluconate and strontium PCA or the combination of at least two of the strontium chloride, the strontium chloride hexahydrate and the strontium hydroxide.

Strontium is an indispensable microelement for maintaining the growth of a living body, which is inherent to the human body, the strontium plays a plurality of biological activities in the human body, the particle size of strontium ions is small, and the strontium ions are easier to permeate into skin and hair compared with organic macromolecules.

Meanwhile, the invention also considers that the shampoo is mostly provided with an anionic surfactant, and the strontium ions belong to cationic strong electrolyte alkaline earth metals, so as to avoid the following adverse effects caused by the neutralization reaction of the anionic surfactant and the strontium ions: (1) The effects of the surfactant and the strontium ions cannot be fully exerted; (2) The shampoo system is unstable, and the phenomenon of demulsification and layering is easy to generate; (3) The thickening agent is difficult to thicken, the viscosity of the shampoo is difficult to improve, the invention divides the components into two parts, provides the two components to be separately packaged, and pumps out and mixes the components together when in use, thereby fully ensuring the stability and the efficacy of the components in a system. In order to solve the problem that the metal ions in the shampoo destroy the emulsification system, the method adds a metal ion chelating agent such as EDTA salt, but the EDTA salt is identified as a persistent organic pollutant and is not friendly to the environment, and the invention overcomes the technical defects.

The shampoo is prepared by compounding strontium-containing compounds, other conditioners, surfactants, thickeners, lubricants, foam boosters, humectants, pH regulators, preservatives and other components, and the raw materials are mutually promoted, so that the shampoo has the effects of cleaning and maintaining scalp and cleaning and maintaining hair.

The combination of at least two of the above-mentioned materials, such as the combination of strontium chloride and strontium chloride hexahydrate, the combination of strontium chloride and strontium acetate, the combination of strontium chloride and strontium hydroxide, the combination of strontium chloride and strontium citrate, etc., can be selected in any combination manner, and will not be described herein again.

Preferably, the conditioning agent in the second component further comprises copper peptide.

The copper peptide can promote hair papilla cell proliferation and hair growth factor expression, has effects of resisting hair follicle aging, preventing alopecia, acting as powerful tissue protection and anti-inflammatory agent, protecting injured tissue from further damage due to oxidation, and promoting hair growth and wound healing. It also has effects in maintaining skin supporting structure (collagen, glycoprotein, elastin, etc.), reducing wrinkle, and inhibiting inflammation. The invention also creatively discovers that the copper peptide and the strontium-containing compound are matched for use, and have a synergistic effect in the aspect of scalp care.

Preferably, the mass ratio of the copper peptide to the strontium-containing compound is 1 (10-50), for example, 1.

Preferably, the conditioning agent in the first component comprises any one of allantoin, dendrobium officinale extract, glyceryl cocoate, guar hydroxypropyl trimonium chloride, hydrolyzed silk protein or panthenol or a combination of at least two of the above.

The combination of at least two of the above components, such as the combination of allantoin and the dendrobium officinale extract, the combination of the dendrobium officinale extract and the glyceryl cocoate, the combination of guar hydroxypropyl trimonium chloride and the hydrolyzed silk protein, and the like, can be selected in any combination mode, and is not repeated herein.

Preferably, the conditioning agent in the first component comprises a combination of allantoin, dendrobium officinale extract, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein and panthenol.

The hydrolyzed silk protein can be crosslinked with protein groups exposed at the damaged part of the hair, so that the damage is repaired, and the toughness of the hair is improved; panthenol is a vitamin B5 derivative, commonly known as "previtamin B5", and can stimulate skin cell division and regeneration, prevent hair split, increase hair density, and improve hair luster; the guar gum hydroxypropyl trimethyl ammonium chloride plays a role in resisting static and forming a film, and hair has better combing property after being washed; the glycerol cocoate can be used for supplementing oil in a surfactant system, has intersolubility with the oil, low viscosity, good ductility and good skin permeability, can moisten skin, increase the lubricating feeling of hair and maintain the oil balance of scalp and hair; the dendrobium officinale extract has very strong moisturizing function on the skin, and the water-soluble polysaccharide contained in the dendrobium officinale extract has very good antioxidation effect, can enhance the immunologic function of the skin, and also can resist bacteria, diminish inflammation and repair skin injury; allantoin can make hair supple and non-split.

The conditioner in the first component of the shampoo provided by the invention preferably combines the above modes to enable the shampoo to have better effects on scalp nourishing and hair nourishing.

Preferably, the surfactant comprises any one of ammonium laureth sulfate, potassium cocoyl hydrolyzed oat protein, octyl/decyl glucoside, lauryl glucoside, sodium alpha-alkenyl sulfonate, sodium methylcocoyltaurate, amidopropyl trimethylammonium ricinoleate, polyethylene glycol stearate, cetearyl alcohol, or a combination of at least two thereof.

The combination of at least two of the compounds, such as the combination of ammonium laureth sulfate and potassium cocoyl hydrolyzed oat protein, the combination of lauryl glucoside and sodium alpha-alkenyl sulfonate, the combination of sodium methyl cocoyl taurate and ricinoleic acid amidopropyl trimethyl ammonium chloride, and the like, can be selected in any combination mode, and is not repeated herein.

Wherein the ammonium laureth sulfate, the potassium cocoyl hydrolyzed oat protein, octyl/decyl glucoside, lauryl glucoside, alpha-sodium alkenyl sulfonate, sodium methyl cocoyl taurate and ricinoleic acid amidopropyl trimethyl ammonium chloride mainly play a role in cleaning, decontaminating and foaming; wherein the polyethylene glycol stearate and the cetostearyl alcohol mainly play roles in keeping the oil and water balance of the system and stabilizing the system.

According to a preferred technical scheme, the first component comprises 15-30% of surfactant, 5-15% of foam booster, 1-10% of conditioner, 1-5% of thickening agent, 1-5% of lubricant, 0.1-0.5% of preservative, 0.05-0.5% of pH regulator and water, wherein the mass of the two-component shampoo with scalp nourishing efficacy is 100%;

the second component comprises 1-5% of humectant, 1-5% of conditioner and 5-15% of water.

The mass percentage of the surfactant can be 15%, 18%, 20%, 22%, 25%, 28%, 30% and the like. The foam enhancer can be used in an amount of 5%, 8%, 10%, 12%, 15% by mass. The conditioner in the first component can be 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10% and the like by mass. The mass percentage of the thickening agent can be 1%, 2%, 3%, 4%, 5% and the like. The mass percentage of the lubricant can be 1%, 2%, 3%, 4%, 5% and the like. The preservative can be 0.1%, 0.2%, 0.3%, 0.4%, 0.5% and the like in percentage by mass. The content of the pH regulator can be 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5% and the like in percentage by mass. The mass percentage of the humectant can be 1%, 2%, 3%, 4%, 5% and the like. The conditioner in the second component can be 1%, 2%, 3%, 4%, 5% and the like in percentage by mass. The mass percentage of water in the second component can be 5%, 7%, 8%, 9%, 10%, 12%, 14%, 15%, etc.

Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.

Preferably, the foam booster comprises any one of cocamidopropyl betaine, alkylolamide, propylene glycol monolaurate, acrylic/VA copolymer or a combination of at least two thereof.

The combination of at least two of the above-mentioned compounds, such as the combination of cocamidopropyl betaine and alkylolamide, the combination of alkylolamide and propylene glycol monolaurate, etc., can be selected in any combination manner, and is not described in detail herein.

Preferably, the thickener comprises any one of polyquaternium-7, PEG-150 distearate, xanthan gum, guar gum, algin, hydroxyethyl cellulose or a combination of at least two thereof.

The combination of at least two of the above-mentioned quaternary ammonium salt-7 and PEG-150 distearate, the combination of xanthan gum and guar gum, the combination of alginate gum and hydroxyethyl cellulose, etc., can be selected from any other combination, and are not described herein again.

Preferably, the lubricant comprises a silicone oil such as amodimethicone (and) cetrimide (and) trideceth-12, dimethicone (and) laureth-23 (and) C12-15 alkanolpolyether-3, cyclopentadimethicone (and) dimethiconol, and the like.

Preferably, the moisturizer comprises any one of hyaluronic acid, sodium hyaluronate, propylene glycol, glycerol, panthenol or a combination of at least two thereof.

The combination of at least two of the above-mentioned compounds, such as a combination of hyaluronic acid and sodium hyaluronate, a combination of sodium hyaluronate and propylene glycol, a combination of glycerol and panthenol, etc., can be selected from any other combination modes, and are not described herein again.

Preferably, the hyaluronic acid is a combination of macromolecular hyaluronic acid, medium molecular hyaluronic acid and small molecular hyaluronic acid.

Preferably, the hyaluronate is a combination of a macromolecular hyaluronate, a medium molecular hyaluronate and a small molecular hyaluronate.

The macromolecular hyaluronic acid refers to hyaluronic acid with a molecular weight of more than 5000, the medium molecular hyaluronic acid refers to hyaluronic acid with a molecular weight of 1000-5000, and the small molecular hyaluronic acid refers to hyaluronic acid with a molecular weight of less than 1000.

Wherein the macromolecular hyaluronic acid can form a layer of breathable film on the scalp and hair surface, so that the skin is smooth and moist, the invasion of external bacteria, dust and ultraviolet rays can be blocked, and the skin is protected from being damaged; the medium molecular hyaluronic acid can tighten the scalp and keep moisture for a long time; the small molecular hyaluronic acid can penetrate into dermis, has effects of slightly dilating capillary, increasing blood circulation, improving metabolism, promoting scalp nutrition absorption, increasing skin elasticity, and delaying skin aging. And the hyaluronic acid can be combined with strontium ions in the strontium-containing compound to react to generate strontium hyaluronate, so that the metal ions strontium can exist in a shampoo system more stably, and other easily crystallized strontium salts are prevented from being formed and separated out.

Preferably, the first component further comprises a fragrance and/or a hueing agent.

The aromatic such as essence is used for increasing the fragrance of the product, and the fragrance is retained after shampooing, so that the product is pleasant. The toner is used for adjusting the color and brightness of the system, such as a pearlescent slurry.

In a second aspect, the present invention provides a method for preparing a two-component shampoo with scalp nourishing effect according to the first aspect, wherein the method for preparing the two-component shampoo comprises the following steps:

respectively mixing the raw materials in the first component and the second component to obtain the first component and the second component.

The preparation method of the bi-component shampoo with the scalp nourishing effect, which is disclosed by the invention, is simple in process and easy to operate, and is very suitable for large-scale industrial production.

Preferably, the preparation method of the first component comprises the following steps:

(1) Mixing water with a surfactant, a foam booster and a part of conditioner to obtain a component A;

(2) Mixing the component A with a thickening agent, a lubricant and the rest of a conditioning agent to obtain a component B;

(3) And mixing the component B with other residual raw materials to obtain a first component.

Preferably, the part of the conditioning agent in the step (1) comprises allantoin and dendrobium officinale extract.

Preferably, the mixing of step (1) is performed under stirring, the stirring is performed at 75-90 deg.C (e.g., 75 deg.C, 78 deg.C, 80 deg.C, 82 deg.C, 85 deg.C, 88 deg.C, 90 deg.C, etc.) for 15-30min (e.g., 15min, 17min, 18min, 20min, 23min, 25min, 30min, etc.), and the stirring speed is 20-35r/min (e.g., 20r/min, 22r/min, 25r/min, 30r/min, 35r/min, etc.). Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.

Preferably, the mixing in step (2) is performed under stirring, the stirring is performed at 40-55 ℃ (e.g., 40 ℃, 42 ℃, 45 ℃,48 ℃, 50 ℃, 52 ℃, 55 ℃ and the like) for 15-30min (e.g., 15min, 17min, 18min, 20min, 23min, 25min, 30min and the like), and the stirring speed is 15-30r/min (15 r/min, 17r/min, 18r/min, 20r/min, 23r/min, 25r/min, 30r/min and the like). Other specific values within the above ranges can be selected, and are not described in detail herein.

Preferably, the mixing in step (3) is performed under stirring, the stirring is performed at 40-55 deg.C (e.g., 40 deg.C, 42 deg.C, 45 deg.C, 48 deg.C, 50 deg.C, 52 deg.C, 55 deg.C, etc.) for 15-30min (e.g., 15min, 17min, 18min, 20min, 23min, 25min, 30min, etc.), and the stirring speed is 15-30r/min (15 r/min, 17r/min, 18r/min, 20r/min, 23r/min, 25r/min, 30r/min, etc.). Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.

Preferably, the pH of the first component is from 5.5 to 6.5.

Preferably, the preparation method of the second component comprises: stirring humectant, conditioner and water at 30-55 deg.C (such as 30 deg.C, 35 deg.C, 40 deg.C, 45 deg.C, 50 deg.C, 55 deg.C) for 10-40min (such as 10min, 15min, 20min, 25min, 30min, 35min, 40 min).

The hair conditioner body system prepared by the preparation method with the specific technical parameters is stable and has lasting effect.

Compared with the prior art, the invention has the following beneficial effects:

the strontium-containing compound is creatively added into the shampoo product, and the strontium element is utilized to promote the biological activities of collagen formation, angiogenesis induction, cell endothelial proliferation promotion and the like to maintain scalp vitality, nourish hair follicles and maintain the basic environment for hair growth, so that stronger and healthy hair is grown, and the strontium enters the human body through the scalp to play a role in supplementing trace elements.

Furthermore, the copper peptide can promote the proliferation of hair papilla cells and the expression of hair growth factors, is used for resisting hair follicle aging and preventing alopecia, is used as a powerful tissue protection and anti-inflammatory agent, protects injured tissues from further damage caused by oxidation, and has the effects of promoting hair growth, wound healing and the like.

Meanwhile, the invention also considers that the shampoo mostly uses anionic surfactant, and strontium ions belong to cationic strong electrolyte alkaline earth metal, so as to avoid the following adverse effects caused by the neutralization reaction of the anionic surfactant and the strontium ions: (1) The efficacy of both the surfactant and the strontium ion cannot be fully exerted; (2) The shampoo system is unstable, and the phenomenon of demulsification and delamination is easy to generate; (3) The thickening agent is difficult to play a thickening role, the viscosity of the shampoo is difficult to improve, the components are divided into two parts, the two components are separately packaged, and the two components are pumped out and mixed together when in use, so that the stability and the effect of the components in a system are fully ensured. In order to solve the problem that the metal ions in the shampoo destroy the emulsification system, the method adds a metal ion chelating agent such as EDTA salt, but the EDTA salt is identified as a persistent organic pollutant and is not friendly to the environment, and the invention overcomes the technical defects.

Detailed Description

To further illustrate the technical means and effects of the present invention, the following further describes the technical solution of the present invention with reference to the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.

Some of the raw material source information for the following examples and comparative examples is as follows:

the hydrolyzed fibroin is obtained from Zhengzhou space-control biotechnology limited;

the amino silicone oil emulsion is MEM-0949 amino silicone oil emulsion;

the organic silicon emulsion is SSE-762 organic silicon emulsion;

the hyaluronic acid is a mixture of macromolecular hyaluronic acid (haixin biological products limited company in carumurus), medium molecular hyaluronic acid (minrui chemical products limited company in zheng zhou), and small molecular hyaluronic acid (sinkyuno biological technology limited company) in a mass ratio of 1;

the preservative is a mixture of the dianthin alcohol 68 and the carnation ketone in a mass ratio of 1;

the dendrobium officinale extract is a product which is purchased from Xianruilin biotechnology limited and has the extraction rate of 50;

other materials were purchased from commercial sources.

Example 1

The present embodiment provides a two-component shampoo with scalp nourishing effect, and the formula table is shown in the following table:

the preparation method comprises the following steps:

(1) Mixing water with surfactant, foam booster, allantoin, and herba Dendrobii extract at 80 deg.C, stirring at 30r/min for 20min to obtain component A;

(2) Mixing the component A with thickener, lubricant, glyceryl cocoate, guar hydroxypropyl trimethyl ammonium chloride, hydrolyzed fibroin and panthenol at 45 deg.C for 30min at 20r/min to obtain component B;

(3) Mixing the component B with the rest raw materials of the first component at 45 deg.C, stirring at 20r/min for 20min to obtain the first component.

(4) Mixing and stirring the raw materials of the second component at 45 ℃ for 25min at a stirring speed of 30r/min to obtain the second component.

(5) Filling, and respectively filling the first component and the second component in different positions of a pump head bottle by adopting a special dual-component shampoo pump head bottle. When in use, the pump head is pressed, and the two components are extruded out simultaneously according to the designed proportion.

Example 2

The present embodiment provides a two-component shampoo with scalp nourishing efficacy, and the formula table is as follows:

the preparation method comprises the following steps:

(1) Mixing water with surfactant, foam booster, allantoin, and herba Dendrobii extract at 85 deg.C, stirring at 20r/min for 30min to obtain component A;

(2) Mixing component A with thickener, lubricant, glyceryl cocoate, guar hydroxypropyl trimethyl ammonium chloride, hydrolyzed fibroin, and panthenol at 50 deg.C for 20min at stirring speed of 30r/min to obtain component B;

(3) Mixing the component B with the rest raw materials of the first component at 50 deg.C, stirring at 15r/min for 30min to obtain the first component.

(4) Mixing and stirring the raw materials of the second component at the temperature of 50 ℃ for 30min at the stirring speed of 15r/min to obtain the second component.

Example 3

The present example provides a two-component shampoo with scalp nourishing efficacy, and the formula table is different from that of example 1 only in that strontium chloride 3% and copper peptide 0.1% are replaced by strontium chloride 3.1%, and other components and contents are all kept unchanged. The preparation method is referred to example 1.

Example 4

The present example provides a two-component shampoo with scalp nourishing effect, and the formula table only differs from example 1 in that 3% of strontium chloride and 0.1% of copper peptide are replaced by 3.1% of copper peptide, and other components and contents are all kept unchanged. The preparation process is as in example 1.

Example 5

The present example provides a two-component shampoo with scalp nourishing efficacy, and the formula table differs from example 1 only in that 0.15% of allantoin, 0.15% of dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyl trimethyl ammonium chloride, 3% of hydrolyzed silk protein, 0.5% of panthenol are replaced by 0.3% of allantoin, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyl trimethyl ammonium chloride, 3% of hydrolyzed silk protein, 0.5% of panthenol, and other components and contents are kept unchanged. The preparation process is as in example 1.

Example 6

The present example provides a two-component shampoo with scalp nourishing efficacy, and the formula table differs from example 1 only in that 0.15% of allantoin, 0.15% of dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyl trimethyl ammonium chloride, 3% of hydrolyzed silk protein, 0.5% of panthenol are replaced by 0.3% of dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyl trimethyl ammonium chloride, 3% of hydrolyzed silk protein, 0.5% of panthenol, and other components and contents are kept unchanged. The preparation method is referred to example 1.

Example 7

The present example provides a two-component shampoo with scalp nourishing efficacy, and the formula table differs from example 1 only in that 0.15% of allantoin, 0.15% of dendrobium officinale extract, 1% of glyceryl cocoate, 0.5% of guar hydroxypropyl trimethyl ammonium chloride, 3% of hydrolyzed silk protein, 0.5% of panthenol are replaced by 0.15% of allantoin, 0.15% of dendrobium officinale extract, 1% of guar hydroxypropyl trimethyl ammonium chloride, 3% of hydrolyzed silk protein, 1% of panthenol, and other components and contents are kept unchanged. The preparation process is as in example 1.

Example 8

The present example provides a two-component shampoo with scalp nourishing efficacy, and the formula table differs from example 1 only in that allantoin 0.15%, dendrobium officinale extract 0.15%, coco glyceride 1%, guar hydroxypropyltrimonium chloride 0.5%, hydrolyzed silk protein 3%, panthenol 0.5% are replaced with allantoin 0.15%, dendrobium officinale extract 0.15%, coco glyceride 2%, hydrolyzed silk protein 3%, and other components and contents are kept unchanged. The preparation method is referred to example 1.

Comparative example 1

This comparative example provides a two-component shampoo, the formulation table differing from example 1 only in that it contained no strontium chloride, the amount of which was supplemented with water, and the other components and amounts remained the same. The preparation process is as in example 1.

Comparative example 2

The comparative example provides a shampoo, the formula table is the same as that of example 1, and the preparation method is as follows:

(1) Mixing water with surfactant, foam booster, allantoin and herba Dendrobii extract at 80 deg.C, stirring at 30r/min for 20min to obtain component A;

(2) Mixing the component A with thickener, lubricant, glyceryl cocoate, guar gum hydroxypropyl trimethyl ammonium chloride, hydrolyzed fibroin and panthenol at 45 deg.C, stirring at 20r/min for 30min to obtain component B;

(3) And mixing the component B, other rest raw materials of the first component and all raw materials of the second component at 45 ℃ and stirring for 30min at the stirring speed of 25r/min to obtain the shampoo.

Test example 1

The shampoos prepared in examples 1-8 were evaluated for safety:

selecting 80 social volunteers with the age of 20-45 years according to requirements, randomly dividing the social volunteers into 8 groups, and respectively trying the shampoos prepared in the examples 1-8 according to the groups, putting the shampoos into a spot tester chamber, and carrying out no treatment on control holes. The spot test device with the test substance is applied to the inner side of the forearm of the subject with hypoallergenic tape, and is applied to the skin uniformly by pressing with the palm for 24h. Skin reactions were observed at 30min (after disappearance of the indentation), 24h and 48h after removal of the plaque from the test article, respectively, according to the criteria of table 1. The test results are shown in Table 2.

TABLE 1

TABLE 2

The results show that: examples 1 to 8 of the invention are all negative reactions, which show that the shampoo disclosed by the invention is safe and mild and does not produce adverse reactions such as skin irritation, sensitization and the like.

Test example 2

The shampoos prepared in examples 1 to 8 and comparative examples 1 to 2 were subjected to the oil-controlling effect test:

100 volunteers, male 25-50 years old, were selected and randomly divided into 10 groups of 10 persons, each group was cleaned of scalp with the same amount of shampoo provided in examples 1-8 and comparative examples 1-2, and the hair was not cleaned two days before the test. During the test period, hair bleaching and dyeing were prohibited, other care products could not be used, and subjects could not stop using the products except in special cases. The SEBUMETER is adopted to collect the scalp oil content to evaluate the scalp oil secretion state. The SEBUMETER method is based on the principle of photometer, a special extinction adhesive tape with the thickness of 0.1mm absorbs grease on human skin and then becomes a semitransparent adhesive tape, the light transmittance of the adhesive tape changes, the more grease is absorbed, the greater the light transmittance is, and therefore the content of scalp grease can be measured. The test conditions are strictly that after hair washing for 48 hours at the temperature of 22 +/-1 ℃ by using each sample to be tested, measuring 5 different parts of the scalp by using SEBUMER, averaging, and calculating the reduction rate of the content of the scalp oil after using each sample (the result is presented by the average value);

the specific test results are shown in table 3:

TABLE 3

From the data in table 1: the bi-component shampoo has good effects of cleaning grease and long-acting oil control, can reduce the grease content of the scalp by more than 18% after 48 hours, and has certain synergistic effect on maintaining the scalp environment to be stable and the oil-water balance by the strontium-containing compound and the copper peptide; meanwhile, compared with the product of comparative example 2, the shampoo adopting the bi-component design has better efficacy and more remarkable oil control effect.

Test example 3

Scalp cleansing effect test was performed on the shampoos prepared in examples 1 to 8 and comparative examples 1 to 2:

selecting 50 volunteers with obvious symptoms of scalp itch and dandruff, and male with the age of 25-50 years, randomly dividing into 10 groups, 5 persons in each group, and respectively taking an appropriate amount of the shampoos provided in examples 1-8 and comparative examples 1-2 to clean scalp and hair; the shampoo using method comprises the following steps: the hair is washed 1 time 3 days per person, 10 times are carried out totally, and index evaluation is carried out 3 days after the end of the last 1 time. No other hair washing and conditioning products were used during the test. Meanwhile, the experimenter observes dandruff symptoms before and after the test of the test population, records the scores of each group, and calculates the average value of the scores of each group; meanwhile, the number of red and swollen scalp is observed, and the degree of itching feeling is inquired.

Dandruff evaluation criteria: 5 min-without scurf; 4 min-small powdery grey rough scale; 3 min-small to medium sized chips; score 2-large, thin chips loosely associated with the scalp; 1 min-large adhesive chips; 0 point-white to yellow thick scales that adhere tightly to the scalp;

evaluation standard of scalp itching and red swelling: 5 minutes-no phenomenon; score 4-not evident; 3 min-slight; 2 min-medium; score 1-severity; 0 point-very severe.

Specific test results are shown in table 4 (results are presented as mean):

TABLE 4

From the data in table 4 it can be seen that: the bi-component shampoo has good effects of removing dandruff and inhibiting scalp pruritus and redness, and the strontium-containing compound and the copper peptide have certain synergistic effect in maintaining scalp environment stability, removing dandruff and inhibiting scalp pruritus and redness; meanwhile, compared with the product of comparative example 2, the shampoo adopting the bi-component design has better efficacy and more remarkable effects in the aspects.

Test example 4

200 volunteers (average alopecia is about 200 per day) of common alopecia patients with alopecia are randomly selected, half of men and women are 23-55 years old, and the volunteers are divided into an experimental group 1-8, a comparative example group 1-2, 20 persons in each group and 10 men and 10 women. The using method comprises the following steps: the hair growth was observed every 3 days for 90 days in all test sessions, and the results are shown in table 5 (the results are presented as averages) for each group of volunteers:

TABLE 5

From the data in table 5, it can be seen that: the bi-component shampoo has the remarkable effects of stimulating hair follicles of the scalp, promoting the growth and the regeneration of hair and preventing alopecia, and the strontium-containing compound and the copper peptide have remarkable synergistic effect on the effects; meanwhile, compared with the product of comparative example 2, the shampoo adopting the dual-component design has better efficacy and more remarkable effects in the aspects.

Test example 5

Evaluation of hair smoothness:

the smoothness was determined by the friction coefficient, 10 hairs were randomly selected from each volunteer in test example 4, arranged and fixed on a glass slide, combed and slid from the root to the tip of the hair with a probe, the average friction coefficient was measured and classified into three classes (less than 0.15, 0.15-0.20, and more than 0.20), and the number of people in each class was recorded. The results are shown in Table 6.

TABLE 6

From the data in table 6 it can be seen that: after the volunteers use the shampoo provided by the invention, the smoothness of the hair is obviously improved. And the composition formula of the shampoo obviously influences the effect of the shampoo on the smoothness of hair.

The applicant states that the present invention is to illustrate a two-component shampoo with scalp nourishing effect and a preparation method thereof through the above embodiments. However, the present invention is not limited to the above-described embodiments, that is, it does not mean that the present invention must be implemented by the above-described embodiments. It should be understood by those skilled in the art that any modifications of the present invention, equivalent substitutions of the raw materials of the product of the present invention, and the addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.

The preferred embodiments of the present invention have been described in detail, however, the present invention is not limited to the specific details of the above embodiments, and various simple modifications may be made to the technical solution of the present invention within the technical idea of the present invention, and these simple modifications are within the protective scope of the present invention.

It should be noted that, in the above embodiments, the various features described in the above embodiments may be combined in any suitable manner, and in order to avoid unnecessary repetition, the present invention does not separately describe various possible combinations.

Claims

1. The two-component shampoo with the scalp nourishing effect is characterized by comprising a first component and a second component;

2. The two-pack shampoo having scalp nourishing effect of claim 1 wherein the conditioning agent in the second pack further comprises copper peptide;

preferably, the mass ratio of the copper peptide to the strontium-containing compound is 1 (10-50).

3. The two-component shampoo with scalp nourishing effect as claimed in claim 1 or 2 wherein the conditioning agent in the first component comprises any one or a combination of at least two of allantoin, dendrobium officinale extract, glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydrolyzed silk protein or panthenol;

4. Two-component shampoo with scalp nourishing efficacy according to any one of claims 1 to 3 wherein the surfactant comprises any one of ammonium laureth sulfate, potassium cocoyl hydrolyzed oat protein, octyl/decyl glucoside, lauryl glucoside, sodium alpha-alkenyl sulfonate, sodium methylcocoyltaurate, ricinoleic acid amidopropyl trimethyl ammonium chloride, polyethylene glycol stearate, cetearyl alcohol, or a combination of at least two thereof.

5. The two-component shampoo with scalp nourishing effect according to any one of claims 1 to 4, wherein the first component comprises 15 to 30% of a surfactant, 5 to 15% of a foam booster, 1 to 10% of a conditioner, 1 to 5% of a thickener, 1 to 5% of a lubricant, 0.1 to 0.5% of a preservative, 0.05 to 0.5% of a pH regulator and water, based on 100% by mass of the two-component shampoo with scalp nourishing effect;

6. The two-component shampoo with scalp nourishing efficacy according to any one of claims 1-5, wherein the foam booster comprises any one of cocamidopropyl betaine, alkylolamide, propylene glycol monolaurate, acrylic acid (ester)/VA copolymer or a combination of at least two of them;

preferably, the thickener comprises any one of polyquaternium-7, PEG-150 distearate, xanthan gum, guar gum, seaweed gum and hydroxyethyl cellulose or a combination of at least two of the substances;

preferably, the lubricant comprises silicone oil.

7. The two-pack shampoo having a scalp-nourishing effect according to any one of claims 1 to 6, wherein the moisturizer comprises any one or a combination of at least two of hyaluronic acid, sodium hyaluronate, propylene glycol, glycerin and panthenol;

preferably, the hyaluronic acid is a combination of macromolecular hyaluronic acid, medium molecular hyaluronic acid and small molecular hyaluronic acid;

preferably, the hyaluronate is a combination of a macromolecular hyaluronate, a medium molecular hyaluronate and a small molecular hyaluronate;

8. The method for preparing the two-component shampoo with the scalp nourishing effect according to any one of claims 1 to 7, wherein the preparation method comprises the following steps:

9. The method for preparing a two-component shampoo with scalp nourishing effect as claimed in claim 8, wherein the method for preparing the first component comprises:

10. The method for preparing a shampoo having a scalp nourishing effect as set forth in claim 9, wherein the part of the conditioner of the step (1) includes allantoin and the extract of Dendrobium officinale;

preferably, the mixing in the step (1) is carried out under stirring, the stirring is carried out at 75-90 ℃ for 15-30min, and the stirring speed is 20-35r/min;

preferably, the mixing in the step (2) is carried out under stirring, the stirring is carried out at 40-55 ℃ for 15-30min, and the stirring speed is 15-30r/min;

preferably, the mixing in the step (3) is carried out under stirring, the stirring is carried out at 40-55 ℃ for 15-30min, and the stirring speed is 15-30r/min;

preferably, the pH of the first component is 5.5-6.5;

preferably, the preparation method of the second component comprises: stirring the humectant, the conditioner and water at 30-55 deg.C for 10-40 min.