KR101509608B1 - Composition for improving scalp and hair condition - Google Patents

Composition for improving scalp and hair condition Download PDF

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KR101509608B1
KR101509608B1 KR20140192508A KR20140192508A KR101509608B1 KR 101509608 B1 KR101509608 B1 KR 101509608B1 KR 20140192508 A KR20140192508 A KR 20140192508A KR 20140192508 A KR20140192508 A KR 20140192508A KR 101509608 B1 KR101509608 B1 KR 101509608B1
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hair
extract
weight
composition
scalp
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KR20140192508A
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Korean (ko)
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신용철
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비오엠코스메틱 주식회사
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair

Abstract

The present invention relates to a composition for improving scalp and hair condition, more particularly, containing as an active ingredient Western rose extract, iris extract, Morus extract, Centella asiatica extract, green tea extract, mugwort extract, the extract comprising the uiyiin and Cnidium extract. According to the present invention, the invention containing as an active ingredient natural extracts is stable even with extended period of use and is effective in preventing hair loss and fostering hair growth through scalp cleaning and sterilization, and nutrition supply. In addition, an excellent conditioning effect can be obtained by moisturizing and nourishing hair, and giving a gloss thereto.

Description

두피 및 모발 상태 개선용 조성물{Composition for improving scalp and hair condition}TECHNICAL FIELD The present invention relates to a composition for improving scalp and hair condition,

본 발명은 두피 및 모발 상태 개선용 조성물에 관한 것으로, 더욱 상세하게는 유효성분으로서 서양장미꽃추출물, 창포추출물, 상백피추출물, 병풀추출물, 녹차추출물, 쑥추출물, 의이인추출물 및 천궁추출물을 포함하여 두피 및 모발의 상태를 개선하여 탈모를 예방하며 양모를 촉진하는 조성물에 관한 것이다.
The present invention relates to a composition for improving scalp and hair condition, and more particularly, to a composition for improving scalp and hair condition. More specifically, the present invention relates to a composition for improving scalp and hair condition, And a composition for improving hair condition to prevent hair loss and promote wool.

평균적으로 사람의 모발의 개수는 약 10만에서 12만 개이다. 모발은 발생, 성장, 퇴화, 휴지기라는 라이프 사이클이 있으며 휴지기에 돌입한 머리카락이 보통 하루에 50~100개 정도 빠지는 것이 정상이다. 모발은 일정기간 자라면 빠지고 새로운 모발이 난다. 손톱이나 발톱과는 달리 '자라고-쉬고-빠지고'하는 주기를 가지는 것이다. 털갈이를 하는 동물의 경우 전체 털의 모주기(毛週期)가 동일하기 때문에 털이 동시에 빠지고 새로 나는 이른바 털갈이를 하게 된다. 그러나 인간의 모발은 각각 독자적인 모주기를 갖고 있기 때문에 털갈이 없이 항상 일정한 모발 수를 유지하게 된다.On average, the number of human hair is about 100,000 to 120,000. There is a life cycle of hair development, growth, degeneration and dormancy. It is normal that the hair that enters the dormant period usually falls in 50 ~ 100 times a day. If the hair grows for a certain period of time, it will fall out and bring new hair. Unlike fingernails or claws, it has a cycle of "growing, resting, and falling". In the case of the molting animals, the hairs are falling at the same time because of the same hair follicle cycle (hair follicle period), so that the new hull is molted. However, since each human hair has its own mother cycle, it always maintains a constant number of hair without molting.

인간 모발의 경우는 3년 자란 후 빠지고 다시 그 자리에서 3개월 후 새로 모발이 난다. 모발은 약 8만 개가 있으며 이 중 하루에 70여 개가 빠지며 3개월 전에 빠진 70여 개의 모발은 새로 자라나게 되어 모발은 항상 8만 개를 유지한다.In the case of human hair, it grows after 3 years, and after 3 months from that position, new hair is born. There are about 80,000 hairs, of which 70 are lost a day, and about 70 new hairs left three months ago are newly growing, keeping hair at 80,000 at all times.

그러나 오늘날과 같이 바쁘게 살아가는 현대인들은 각종 스트레스를 받기 쉽다. 이러한 스트레스와 노화에 따른 영향이 탈모에 가장 밀접하게 작용을 한다. 과거 탈모는 유전에 의한 것이라 인식되었지만 최근 탈모는 노화의 한 현상이고 그 시기가 생활 환경의 변화에 따라 앞당겨진다는 점이 큰 문제이다.However, modern people who are busy like today are subject to various stresses. These stresses and the effects of aging are most closely related to hair loss. Hair loss in the past has been recognized as hereditary, but recent hair loss is a phenomenon of aging and it is a big problem that the time is accelerated by changes in the living environment.

탈모증은 기본적으로 모발에너지를 만드는 기능, 즉 모발 에너지 사이클이 정상적으로 작용하지 못해 모근에 에너지 부족현상이 생기기 때문에 발생되는 것으로 알려져 있다.Hair loss is basically caused by the ability to make hair energy, that is, the hair energy cycle does not work normally, resulting in energy shortage in the hair follicle.

모발의 성장과 발육에 필요한 에너지의 생성을 방해한다고 알려진 남성호르몬(Androgen)의 일종인 테스토스테론(Testosteron)은 모낭 주변에 분포하고 있는 5 알파-리덕타아제의 작용으로 그 활성도가 보다 증가한 DHT(Dihydrotestosterone)로 변하게 된다. 활성화된 DHT는 안드로겐 수용체와 결합함으로써 모발의 성장기를 단축하고, 모낭의 크기를 위축시킴으로써 모발을 점차 가늘게 만들며 결국에는 탈모를 유발한다. Testosteron, a type of male hormone (Androgen) that is known to interfere with the production of energy required for hair growth and development, has been shown to act on 5-alpha-reductase (DHT) ). Activated DHT binds to the androgen receptor to shorten the growth period of the hair and atrophies the size of hair follicles, making the hair thinner and eventually causing hair loss.

탈모가 진행되면 모근에 존재하는 모유두가 작아지고 모발의 굵기도 가늘어지며 동시에 모주기가 짧아진다. 즉 3년 자란 후 빠져야 할 털이 1년 자란 후 빠지게 되면 계산적으로 하루에 210여 개가 빠지게 된다. 탈모가 계속 진행되면 모발은 솜털로 변하며 모주기는 더욱 짧아져 조금 자란 후 빠지게 되므로 모발이 가늘어지고 길지 않게 된다.As the hair loss progresses, the papillary hair present in the hair follicles becomes smaller, the thickness of the hair becomes smaller, and the mother period becomes shorter. In other words, if a hair that grows out after 3 years grows one year and then falls out, it will be calculated 210 times a day. When the hair loss continues, the hair turns into fluffy hair, and the hair loss becomes shorter, so that the hair grows a little and then falls off, so that the hair becomes thin and long.

따라서 남성호르몬을 조절할 수 있는 인자를 적용한다면 탈모가 예방될 것이라는 가정하에 의학계에서는 많은 연구를 거듭하여 탈모에 효과적인 신약을 개발하고 있다. 1997년 FDA에서 탈모치료제로 인정받은 남성호르몬 억제제인 프로페시아와 역시 전립선 비대증 치료제이면서 탈모예방에 효과적인 두타, 그리고 외용제이면서 항고혈압제인 미녹시딜(British Journal of Dermatology. 2004: 150: 186~194)은 가장 대표적인 탈모예방 및 발모제들이다.Therefore, if a factor controlling the male hormone is applied, it is assumed that hair loss will be prevented, and the medical field has been repeatedly studied to develop a new drug effective for hair loss. In 1997, the FDA announced that propecia, a male hormone inhibitor, and dandruff which is effective in preventing hair loss, and minoxidil, an external medicine and antihypertensive agent, are the most representative of the treatment of prostate hyperplasia (British Journal of Dermatology. 2004: 150: 186-194) Hair loss prevention and hair growth.

그러나 이러한 탈모예방제나 발모제를 적용할 경우 체내 항상성의 불균형으로 인하여 각종 부작용이 관찰되곤 하는데 대표적으로 성기능 감소나 알레르기, 우울증, 국소염증 등의 예기 하지 않은 각종 부작용이 발생한다. 또한, 탈모는 복합적인 시스템으로 인해 발생하기 때문에 호르몬 억제 등의 협소적인 치료는 근시안적인 처방에 불과하다는 문제점이 있었다.However, when the hair loss preventing agent or the hair removal agent is applied, various side effects are observed due to the imbalance of the homeostasis in the body. Typical examples include unexpected side effects such as sexual dysfunction, allergy, depression and local inflammation. In addition, since hair loss is caused by a complex system, there is a problem that narrow treatment such as hormone suppression is merely a short-sighted prescription.

따라서, 각종 천연물들을 이용한 탈모방지 및 양모용 조성물들이 제안되었는 바, 그 일례로서 대한민국 등록특허공보 제10-0839704에는 들국화의 일종인 구절초를 함유하는 탈모방지 및 모발 생장촉진 조성물이 개시되어 있다. 또한, 대한민국 등록특허공보 제10-0581316호에는 충을자, 감송향, 감국, 도인, 산수유, 토사자, 오미자, 백출, 솔잎 및 당귀의 수종 한약재 혼합 추출액을 함유하는 탈모방지 및 발모 촉진 조성물이 개시되어 있고, 대한민국 등록특허공보 제10-0609210호에는 당귀 뿌리와 우엉뿌리의 에탄올 추출물을 함유함으로써 당귀 뿌리의 β-시토스테롤 성분에 대한 5-α 환원효소의 억제효과와 우엉뿌리의 이눌린 성분에 의한 혈류개선 효과로 탈모방지 효과를 가지는 탈모방지 샴푸의 제조방법이 개시되어 있으며, 대한민국 등록특허공보 제10-0579710호에는 은행잎에서 추출한 징코라이드A, 징코라이드B 및 비로발라이드를 함유하여 비듬방지 효과와 함께 탈모방지 효과를 가지는 샴푸 조성물이 개시되어 있고, 대한민국 등록특허공보 제10-0806125호에는 금과 은을 녹인 금은물에 각종의 천연 한방소재를 넣고 끓여 추출한 추출액을 샴푸 조성물에 혼합하여 탈모방지 및 양모효과를 가지는 샴푸의 제조방법이 개시되어 있다.Accordingly, compositions for hair loss prevention and wool using various natural materials have been proposed. For example, Korean Patent Registration No. 10-0839704 discloses a composition for preventing hair loss and promoting hair growth, which contains a perennial herb, which is a kind of wild persimmon. In addition, Korean Patent Registration No. 10-0581316 discloses a composition for preventing hair loss and promoting hair growth, which comprises a mixed extract of several medicinal herbs such as Bombyxia crassifolia, Gamma radish, Gamooki, Doenjang, Sansui oil, Tozanja, Omija, And Korean Patent Publication No. 10-0609210 discloses that the inhibitory effect of 5-alpha-reductase on the beta -sitosterol component of Angelica gigas root and the inhibitory effect of the inulin component of burdock root on the blood flow A method of manufacturing a hair loss preventing shampoo having an effect of preventing hair loss is disclosed. Korean Patent Registration No. 10-0579710 discloses a method of preventing shampoos containing ginko rye A, ginko rye B and nonrovalide extracted from gingko leaf, A shampoo composition having anti-hair loss effect is disclosed in Korean Patent Publication No. 10-0806125, and gold A mixture of various kinds of boiled extract was extracted into the natural herbal materials in the water to shampoo compositions has been disclosed a method of making a shampoo with hair loss prevention effect and wool.

그러나 탈모방지 및 모발의 양모 효과를 극대화하기 위해서는 1종의 천연물 또는 한약재 만으로는 큰 효과가 없었으며, 탈모방지 및 양모 기능만을 가짐으로써, 모발 컨디셔닝 등의 기능이 결여되는 등의 단점이 있다.
However, in order to prevent hair loss and maximize the effect of hair on the hair, there is a disadvantage that only one kind of natural or herbal medicine material has a great effect, and hair restoration and wool function are only provided.

KR 10-0839704 B1KR 10-0839704 B1 KR 10-0581316 B1KR 10-0581316 B1 KR 10-0609210 B1KR 10-0609210 B1 KR 10-0806125 B1KR 10-0806125 B1

British Journal of Dermatology.(2004: 150: 186~194) British Journal of Dermatology. (2004: 150: 186-194)

따라서, 본 발명에 따른 두피 및 모발 상태 개선용 조성물은, 서양장미꽃추출물, 창포추출물, 상백피추출물, 병풀추출물, 녹차추출물, 쑥추출물, 의이인추출물, 천궁추출물 등을 유효성분으로 함유함으로써, 두피 및 모발의 상태를 개선하여 탈모를 방지하고, 양모를 촉진하도록 하는 것을 목적으로 한다.Accordingly, the composition for improving scalp and hair condition according to the present invention can be used as an effective ingredient for a composition for improving scalp and hair condition, which comprises a western rose flower extract, an iris extract, a manganese bark extract, a centilla mushroom extract, green tea extract, mugwort extract, It is intended to improve hair condition to prevent hair loss and to promote wool.

또한, 천연추출물을 유효성분으로 사용함으로써, 장기간 사용하더라도 부작용이 없도록 하고, 두피뿐 아니라, 모발에도 충분한 영양을 공급하여 모발에 윤기를 부여할 수 있도록 하는 것이다.
In addition, by using the natural extract as an active ingredient, it is possible to prevent side effects even if it is used for a long period of time, and to provide sufficient nutrition to the scalp as well as scalp so as to impart shine to the hair.

상기한 목적을 달성하기 위한 본 발명의 두피 및 모발 상태 개선용 조성물은, 서양장미꽃추출물, 창포추출물, 상백피추출물, 병풀추출물, 녹차추출물, 쑥추출물, 의이인추출물 및 천궁추출물을 유효성분으로 포함하는 것을 특징으로 한다.In order to accomplish the above object, the present invention provides a composition for improving scalp and hair condition, which comprises at least one composition selected from the group consisting of western rose flower extract, iris extract, mulberry bark extract, mulberry leaf extract, green tea extract, mugwort extract, .

상기 추출물은 물, 알코올, 탄화수소계 용매 및 비극성 유기용매 이루어진 군 중 선택된 1종 이상의 용매를 사용하여 추출된 것임을 특징으로 한다.Wherein the extract is extracted using at least one solvent selected from the group consisting of water, an alcohol, a hydrocarbon solvent and a nonpolar organic solvent.

상기 추출물은 조성물 전체에 대하여 0.5~10중량%로 포함하는 것을 특징으로 한다.And the extract is contained in an amount of 0.5 to 10% by weight based on the whole composition.

하이드롤라이즈드케라틴, 하이드롤라이즈드콜라겐, 하이드롤라이즈드실크(Hydrolyzed Silk), 멘톨, 살리실산 및 덱스판테놀을 추가로 더 포함하는 것을 특징으로 한다.Hydrolyzed collagen, hydrolyzed silk, menthol, salicylic acid, and dex-panthenol. ≪ RTI ID = 0.0 >

나이아신아마이드, 하이알루론산, 소듐피씨에이으로 이루어진 군 중 선택된 1종 이상의 것을 추가로 포함하는 것을 특징으로 한다.At least one selected from the group consisting of niacinamide, hyaluronic acid, and sodium PCA.

상기 조성물의 제형은 헤어 샴푸, 헤어 앰플, 헤어 린스, 헤어 컨디셔너, 헤어 트리트먼트, 헤어 토닉, 헤어 로션, 헤어 크림 및 모발 영양화장수 중 어느 하나인 것을 특징으로 한다.
The composition of the composition is any one of a hair shampoo, a hair ampoule, a hair conditioner, a hair conditioner, a hair treatment, a hair tonic, a hair lotion, a hair cream, and a hair nutrition lotion.

본 발명에 따르면 천연 추출물을 유효성분으로 함유함으로써, 장기간 사용하더라도 안정적이며, 두피 청결, 살균 및 영양공급을 통해 탈모예방 및 양모에 효과가 있다. 아울러, 모발에 보습작용을 하고, 영양을 공급하며, 윤기를 부여하여 우수한 컨디셔닝 효과를 갖는다.
According to the present invention, by containing the natural extract as an active ingredient, it is stable even when used for a long time, and is effective for hair loss prevention and wool by cleaning the scalp, sterilizing and nutrition. In addition, it has an excellent conditioning effect by moisturizing the hair, supplying nutrition, and imparting gloss.

이하, 본 발명을 상세히 설명한다.Hereinafter, the present invention will be described in detail.

본 발명은 두피 및 모발의 상태 개선, 즉 두피 청결, 살균 및 진정, 영양공급은 물론, 탈모예방 및 양모의 기능을 가지며, 모발의 보습 및 윤기부여 기능을 갖는 조성물로서, 그 유효성분으로 서양장미꽃추출물, 창포추출물, 상백피추출물, 병풀추출물, 녹차추출물, 쑥추출물, 의이인추출물 및 천궁추출물을 포함한다. 즉, 이러한 유효성분으로 인해 모발의 보호, 보습, 두피 청결 및 살균, 피지 조절, 소염, 발모촉진 및 양모 등의 기능을 갖는 것이다.The present invention relates to a composition having hair follicle moisturizing and gloss-imparting function which has hair follicle preventing function and wool function as well as scalp and hair condition improvement, that is, cleansing of scalp, sterilization and calming and nutrition, Flower extract, iris extract, mulberry bark extract, centilla callus extract, green tea extract, mugwort extract, Uinto extract and cinnabar extract. That is, it has functions of protecting the hair, moisturizing, cleansing and sterilizing the scalp, sebum control, inflammation, hair growth and wool due to the active ingredient.

이하, 본 발명의 조성물에 함유되는 각 추출물에 대하여 살펴본다.Hereinafter, each of the extracts contained in the composition of the present invention will be described.

먼저, 서양장미꽃추출물(Rose Centifolia(Rose Absolute) Flower Extract(Rose Absolute Oil, Organic))은 비타민C가 레몬의 60배 가량이 함유되어 비타민폭탄이라는 명칭을 가질 정도로 풍부한 영양이 있는 성분으로, 풍부한 영양을 모발에 흡수시키면서도, 그 흡수가 빠르고 가벼워 모발 끝에 무거움을 느끼지 않게 해주며, 햇빛이나 열에 노출된 모발을 보호해주고, 건조한 두피에 영양을 공급하며 자극 없이 사용할 수 있다.First, Rose Centipolia (Rose Absolute) Flower Extract (Rose Absolute Oil, Organic) is a rich nutritional ingredient that contains vitamin C in 60 times the amount of lemon and is named vitamin bomb. It absorbs nutrients into the hair, but its absorption is fast and light, so it does not feel heavy at the tips of the hair, protects the hair exposed to sunlight or heat, nourishes the dry scalp and can be used without stimulation.

창포추출물(Acorus Calamus Root Extract)은 모발에 영양을 공급하고, 모발을 검게 해주며, 모근을 튼튼하게 해준다. 또한, 모공이나 모낭에 효과가 좋으며, 마사지 효과와 모공을 건강하게 해주는 성분으로, 모발과 머릿결, 두피를 유해성 활성산소로 인한 손상으로부터 보호해준다. The iris extract (Acorus Calamus Root Extract) nourishes the hair, darkens the hair, and strengthens the hair follicle. It also works well on pores and hair follicles, and provides massage and pore health. It protects hair, hair and scalp from damage caused by harmful active oxygen.

상백피 추출물(Morus Alba Bark Extract)은 뽕나무 뿌리 껍질을 추출한 추출물을 말하며, 멜라민 생성의 중요한 역할을 하는 효소인 티로시나이제를 억제하여 햇빛이나 멜라닌으로 인한 색소침착의 개선과 방지, 억제 효과가 탁월하다. 또한, 활성산소 제거기능도 있으며, 털의 성장을 촉진시켜 발모효과가 우수하고, 소염에도 좋아 민감성 두피의 진정효과도 있다.Morus Alba Bark Extract is an extract of mulberry root bark extract. Suppression of tyrosinase, an enzyme that plays an important role in melamine production, is excellent for improving, preventing and inhibiting pigmentation caused by sunlight and melanin . In addition, it has active oxygen elimination function, promotes hair growth, and has excellent hair growth effect.

병풀추출물(Centella Asiatica Extract)은 마데카소사이드, 아시아티코사이드, 아시아틱애시드, 마데카식애씨드 등의 핵심성분들이 포함되어 있으며, 두피손상을 순하게 케어해준다. 그리고 자극으로 약해진 두피를 진정시키고, 보습막 강화에 도움을 주며, 영양이 손실된 모발을 건강하게 가꾸는데 도움을 주며 풍부한 영양공급 및 손상예방에 도움이 된다.Centella Asiatica Extract contains key ingredients such as Madecaside, Asian Ticoside, Asiatic Acid, and Madeca Acid, and helps to cure scalp. It helps to calm the weakened scalp, help strengthen the moisturizing membrane, help maintain healthy hair loss, and prevent abundant nutrition and damage.

녹차추출물(Camellia Sinensis Leaf Extract)은 녹차의 잎을 물 또는 주정, 초산에틸로 추출하고, 여과하여 제조한 것으로, 항산화작용을 가지며, 폴리페놀과 카테킨 성분이 두피의 노폐물을 제거하고 비듬 및 각질을 덜어주어 두피와 모발을 깨끗하게 해준다.Camellia Sinensis Leaf Extract is made by extracting green tea leaf with water or ethyl acetate and filtering. It has antioxidant activity. Polyphenol and catechin remove the waste of scalp and remove dandruff and keratin. Relieves the scalp and hair.

쑥추출물(Artemisia Vulgaris Extract)은 세포의 노화 지연작용, 알레르기성 질환에 대한 예방효과가 있어, 문제성 두피의 진정작용 및 피지의 분피를 조절해주는 역할을 한다.Artemisia Vulgaris Extract is a preventive effect against delayed aging of cells and allergic diseases, and plays a role of regulating the sedative effect of the problematic scalp and sebum in the sebaceous glands.

의이인추출물(Coix Lacryma-Jobi Ma-yuen Seed Extract)은 주로 전분(Starch), 지질(Fatty oil), 코익솔(Coixol), 스테롤(Sterol), 아미노산, 비타민 B1 및 코익세놀리드(Coixenolide)가 함유되어 있는바, 항염, 진정 및 진통 작용이 있어 두피의 진정 및 염증완화에 도움을 준다.The Coix Lacryma-Jobi Ma-yuen Seed Extract contains mainly Starch, Fatty oil, Coixol, Sterol, Amino acid, Vitamin B1 and Coixenolide. It has anti-inflammatory, soothing and analgesic action, which helps to calm and relieve inflammation of the scalp.

천궁추출물(Cnidium Officinale Root Extract)은 혈액순환을 돕고, 단백질과 비타민E가 풍부해 두피의 노화, 탄력방지에 좋고, 모발재생에 도움을 준다. 그리고 기본적인 세정 능력을 가지고 있어 두발을 청결하게 도와주며, 세정제를 넣을 경우 시너지 효과를 발휘한다. 아울러, 모발에 윤기를 주며 발모를 촉진시키고 건강하게 지켜준다.Cnidium Officinale Root Extract helps blood circulation, rich in protein and vitamin E, helps prevent aging and elasticity of scalp, and helps hair regrowth. And it has basic cleaning ability, it helps to clean the hair, and synergistic effect when cleaning agent is put on. In addition, it shines hair, promotes hair growth and keeps it healthy.

이러한 천연추출물들은 천연재로부터 그 유효성분을 다양한 방법으로 추출하여 사용가능한데, 그 예로서 20 내지 40℃에서 추출용매에 천연재를 침지하여 추출하는 방법, 60 내지 90℃에서 추출용매에 천연재를 넣고 환류하여 추출하는 방법, 20 내지 70℃에서 추출용매에 천연재를 넣고 초음파를 조사하여 추출하는 방법 등을 사용가능하며, 상기한 방법 이외의 방법을 통해서 추출할 수도 있는 것으로, 그 방법을 한정하지 않는다. Such natural extracts can be used by extracting the active ingredient from a natural material by various methods. Examples thereof include a method of extracting a natural material by immersing it in an extraction solvent at 20 to 40 ° C, a method of extracting a natural material at 60 to 90 ° C A method of extracting it by refluxing, a method of extracting by irradiating ultrasound with an extruded material in an extraction solvent at 20 to 70 ° C, and the like, which may be extracted through a method other than the above-mentioned method, I never do that.

그리고 추출용매로는 물, 에탄올, 메탄올, 이소프로판올 등의 저급 알코올, 에틸아세테이트, 아세톤 등의 용매가 이용될 수 있으며, 이외에도 글리세린, 부틸렌글라이콜, 프로필렌글라이콜 등의 다가 알코올류, 메틸아세테이트, 에틸아세테이트, 벤젠, n-헥산, 디에틸에테르, 디클로로메탄, 클로로포름 등의 탄화수소계 용매, 그리고 석유에테르, 메틸아세테이트, 벤젠, 헥산, 클로로포름, 메틸렌클로라이드, 디메틸에테르, 에틸아세테이트 등의 비극성 유기용매도 추출용매로 포함될 수 있는 것으로, 이러한 추출용매를 추출용매와 천연재의 총 중량 대비 90 내지 50중량% 이용하여 추출하는 것이다.The extraction solvent may be a solvent such as lower alcohol such as water, ethanol, methanol, isopropanol, ethyl acetate or acetone. In addition, polyhydric alcohols such as glycerin, butylene glycol and propylene glycol, , A hydrocarbon solvent such as ethyl acetate, benzene, n-hexane, diethyl ether, dichloromethane or chloroform and a nonpolar organic solvent such as petroleum ether, methyl acetate, benzene, hexane, chloroform, methylene chloride, dimethyl ether, The extraction solvent is extracted by using 90 to 50% by weight based on the total weight of the extraction solvent and the natural material.

그리고 상기 본 발명의 천연재 추출물들은 조성물 전체에 대하여 0.5~10중량%로 포함되는 것이 바람직한데, 그 함량이 0.5중량% 미만일 경우 그 역할이 미미하게 되고, 10중량%를 초과할 경우 과량이 되어 생산비용이 증가하며 증진된 작용효과가 나타나지 않으므로, 경제적이지 못하기 때문이다. 아울러, 더욱 바람직하게는 상기 창포추출물, 상백피추출물, 병풀추출물, 녹차추출물, 쑥추출물, 의이인추출물 및 천궁추출물은 각각 0.001~0.15중량%로 포함되며, 서양장미꽃추출물은 0.1~0.5중량%로 포함되는 것인바, 이러한 조성비를 가질 경우 탈모예방 및 양모, 두피 및 모발 상태개선에 더욱 효과적이다. When the content is less than 0.5% by weight, the effect of the present invention is insignificant. When the content is more than 10% by weight, the extract is excessive. This is because the production cost is increased and the enhanced action effect is not exhibited, which is not economical. More preferably, the iris extract, mulberry bark extract, centilla cicada extract, green tea extract, mugwort extract, corynebacterium extract and corynebactii extract are contained in an amount of 0.001 to 0.15% by weight and the extract of western rose flower is contained in an amount of 0.1 to 0.5% If such composition ratio is given, it is more effective in preventing hair loss and improving the condition of wool, scalp and hair.

한편, 본 발명에서는 상기 천연재 추출물들을 반드시 모두 포함하여야 하는 것인바, 천연재 추출물을 선택적으로 1 종 또는 2 내지 7종을 사용한다면, 본 발명에서 요구하는 충분한 효과를 달성할 수 없다. 즉, 본 발명은 상기한 천연재 추출물들이 복합적인 상호작용을 통해 그 효과를 달성하는 것이므로, 상기한 천연재 추출물을 반드시 모두 포함하여야만 한다.
Meanwhile, in the present invention, it is necessary to include all of the ginseng extracts. If one kind or two to seven kinds of ginseng extract are selectively used, sufficient effects required in the present invention can not be attained. That is, the present invention should include all of the above-mentioned ginseng extracts since the above-mentioned ginseng extracts achieve the effect through complex interactions.

또한, 본 발명은 하이드롤라이즈드케라틴(Hydrolyzed Keratin), 하이드롤라이즈드콜라겐(Hydrolyzed Collagen), 하이드롤라이즈드실크(Hydrolyzed Silk), 멘톨(Menthol), 살리실산(Salicylic Acid) 및 덱스판테놀(D-Panthenol)을 추가로 더 포함하는 것이 바람직한데, 이러한 성분을 통해 모발의 수분 밸런스 조절, 손상모 회복, 윤기 부여, 두피 진정, 항균, 비듬방지 효과를 부여한다.The present invention also relates to a pharmaceutical composition comprising at least one selected from the group consisting of Hydrolyzed Keratin, Hydrolyzed Collagen, Hydrolyzed Silk, Menthol, Salicylic Acid and Dextanol -Panthenol). It is preferable to control the moisture balance of the hair, restoration of the damaged hair, luster, scalp soaking, antibacterial and anti-dandruff effect.

상기 하이드롤라이즈드케라틴(Hydrolyzed Keratin)은 일반 모발 제품에서 사용되는 아미노산과 동일한 배합을 식물에서 추출한 식물성 케라틴으로, 모발과 피지에서 자연생성을 증가시키고 모발 수분 밸런스 조절로 촉촉함을 유지시켜 주며, 화학적 코팅이 아닌 자연적인 방법으로 모발의 건강과 활기를 더해준다. 상기 하이드롤라이즈드케라틴은 조성물 내에서 0.001~0.5중량%만큼 포함함이 바람직하다.Hydrolyzed Keratin is a vegetable keratin extracted from plants in the same composition as the amino acids used in ordinary hair products. It increases the natural production of hair and sebum, maintains moisture by controlling hair moisture balance, It is not a coating but a natural way to add health and vitality to your hair. It is preferable that the hydrolized keratin is contained in the composition by 0.001 to 0.5% by weight.

상기 하이드롤라이즈드콜라겐(Hydrolyzed Collagen)은 두피 및 모발에 영양 및 수분을 공급해주는 것은 물론, 두피 진정작용을 해준다. 상기 하이드롤라이즈드콜라겐은 조성물 내에서 0.001~0.5중량%만큼 포함함이 바람직하다.The Hydrolyzed Collagen provides nutrients and moisture to the scalp and hair, as well as scalp soothing. The hydrolized collagen is preferably contained in the composition in an amount of 0.001 to 0.5% by weight.

하이드롤라이즈드실크(Hydrolyzed Silk)는 피부세포를 구성하는 중요한 성분으로, 두피에 흡수되어 보습력을 강화시켜주고, 모발의 구성성분인 미립자 단백질로 구성되어 모발의 큐티클에 흡수되어 손상모를 회복시키고 건강을 되찾아준다. 거칠어진 모발이 엉키면서 손상되는 부분의 마찰을 줄여 마찰손상을 막아준다. 상기 하이드롤라이즈드실크는 조성물 내에서 0.001~0.5중량%만큼 포함함이 바람직하다.Hydrolyzed Silk is an important component that constitutes skin cells. It is absorbed in the scalp and strengthens the moisture. It is composed of fine particle protein, which is a component of hair, absorbed into the cuticle of hair, . Coarse hair tangles to reduce the friction of the damaged area, preventing friction damage. It is preferable that the hydrolyzed silicate is contained in an amount of 0.001 to 0.5% by weight in the composition.

상기 멘톨(Menthol)은 즉각적이면서도 지속적으로 두피에 청량감 내지 상쾌함을 부여하는 효과를 갖는 것으로, 상기 조성물 내에서 0.3중량%만큼 포함함이 바람직하다.Menthol has immediate and sustained effects of imparting refreshing sensation to the scalp, and it is preferably contained in the composition by 0.3% by weight.

상기 살리실산(Salicylic Acid)은 항균, 항염 효능, 비듬방지 효능이 있으며, 또한 각질 제거에도 유용한 것으로, 상기 조성물 내에서 0.25중량%만큼 포함함이 바람직하다.Salicylic Acid has antimicrobial, anti-inflammatory and anti-dandruff properties and is also useful for exfoliation, and it is preferably contained in an amount of 0.25% by weight in the composition.

상기 덱스판테놀(D-Panthenol 은 상처 치유를 촉진하고, 보습효과가 우수하며, 모발의 피질에 침투하여 모간을 강화하고, 두피에 침투하여 모근을 강화하는 효과가 있으며, 상기 조성물 내에서 0.2중량%만큼 포함함이 바람직하다.D-Panthenol has the effect of accelerating wound healing, excelling in moisturizing effect, penetrating into the cortex of the hair to strengthen the hair, penetrate into the scalp and strengthen hair roots, and 0.2 wt% .

즉, 상기한 천연재 추출물과 함께 상기 하이드롤라이즈드케라틴(Hydrolyzed Keratin), 하이드롤라이즈드콜라겐(Hydrolyzed Collagen), 하이드롤라이즈드실크(Hydrolyzed Silk), 멘톨(Menthol), 살리실산(Salicylic Acid) 및 덱스판테놀(D-Panthenol)을 추가로 포함할 경우 더욱 우수한 탈모방지 및 양모, 두피 및 모발의 상태개선 효과를 가질 수 있다.
That is, it is possible to use the hydrolyzed keratin, the hydrolyzed collagen, the hydrolyzed silk, the menthol, the salicylic acid, And Dexamanthenol (D-Panthenol), it is possible to further prevent hair loss and improve the condition of wool, scalp and hair.

또한, 본원발명은 나이아신아마이드, 하이알루론산, 소듐피씨에이로 이루어진 군 중 선택된 1종 이상의 것을 더 포함할 수 있다.In addition, the present invention may further include one or more selected from the group consisting of niacinamide, hyaluronic acid, and sodium PC.

상기 나이아신아마이드(Niacinamide)은 수용성 비타민 B3로서, 멜라민 이동을 감소시켜 깨끗한 피부, 즉 깨끗한 두피를 유지시키는데 도움을 준다. 즉, 멜라민은 기저막에 위치한 멜라노사이트에서 합성된 후에 멜라민을 적재한 멜라노좀(melanosomes) 돌기를 통해서 케라티노사이트(keratinocyte)로 전이되며, 결국은 피부표면으로 멜라민이 이동하게 되는데, 이 멜라노좀의 전이를 억제하는 것이다. 아울러, 지성 트러블 두피의 개선 및 두피 세포를 활성화시켜 콜라겐 분비를 촉진시키는 효과로 노화 두피를 개선하는 효과와, 수분손실을 막고 진피의 미세순환을 자극하여 두피의 장벽을 강화시키는 작용을 한다. 상기 나이아신아마이드는 조성물 내에서 0.001~0.5중량%만큼 포함함이 바람직하다.Niacinamide is a water-soluble vitamin B3 that helps maintain melanin transport and maintain clean skin, a clean scalp. That is, melamine is synthesized in the melanocyte located in the basement membrane and then transferred to keratinocyte through the melanosomes projected with melamine, and eventually melamine migrates to the surface of the skin. It inhibits metastasis. In addition, it improves the aging scalp by improving the oily trouble scalp and activating the scalp cells to promote collagen secretion, and acts to strengthen the barrier of the scalp by stimulating the microcirculation of the dermis, preventing moisture loss. It is preferable that the niacinamide is contained in the composition by 0.001 to 0.5% by weight.

상기 히알루론산(hyaluronic acid)은 피부세포에 꼭 필요한 존재로, 진피에서 수분과 결합하여 세포가 정상적으로 활동할 수 있는 환경을 조성해준다. 두피의 수분균형을 유지하는데 큰 역할을 담당하며, 건조하고 연약한 두피에 최상의 보습제로 사용된다. 건조함 없이 부드럽게 손상 모발에 수분을 공급해준다. 아울러, 히알루론산은 두피와 머리카락에 수분과 영양분, 머리뿌리를 지지하는 힘을 주며, 두피와 머리카락은 히알루론산으로 인해 정상적인 활동을 하게 된다. 상기 히알루론산은 조성물 내에서 0.001~0.5중량%만큼 포함함이 바람직하다.The hyaluronic acid (hyaluronic acid) is a necessary substance for the skin cells, and it binds with the moisture in the dermis to create an environment in which the cells can normally function. It plays a major role in maintaining the moisture balance of the scalp and is best used as a moisturizer on a dry, soft scalp. Provides moisture to damaged hair gently without drying In addition, hyaluronic acid gives the scalp and hair the power to support moisture, nutrients, and hair roots, while the scalp and hair are normal due to hyaluronic acid. The hyaluronic acid is preferably contained in the composition in an amount of 0.001 to 0.5% by weight.

상기 소듐피씨에이(Sodium Pyrrolidone Carboxylic acid)는 포유동물의 피부 조직을 비롯한 여러 조직에서 발견되는 자연물질로, 야채, 과일 또는 당밀 등에 포함된 글루탐산(Glutamic acid)과 아미노산(Amino acid)와 같은 성분들로부터 체내에서 생성된다. 이러한 소듐피씨에이는 히알루론산과 같이 매우 우수한 보습력을 가진 성분으로, 공기 중의 수분을 끌어당겨 표피에 수분을 공급하는 능력이 있다. 특히 소듐피씨에이는 천연보습인자(NMF, Natural Moisturizing Factor)의 하나로, 주변의 공기로부터 수분을 흡수하여 잡아두는 역할을 한다. 즉, 공기 중의 수분을 끌어당겨 두피 및 모발을 촉촉하게 하고 각질층의 수분량을 조절하며, 글리세린보다도 약 50% 이상 향상된 보습능력이 있다. 아울러, 모발을 탄력 있고 유연하게 하여주고, 물리적 손상이나 파마와 같은 화학적 손상으로부터 모발을 보호하여 머릿결을 부드럽게 한다. 상기 소듐피씨에이는 조성물 내에서 0.001~0.5중량%만큼 포함함이 바람직하다.Sodium Pyrrolidone Carboxylic acid is a natural substance found in various tissues including mammalian skin tissues and contains components such as glutamic acid and amino acid contained in vegetables, Lt; / RTI > Such sodium PC has very good moisturizing power, such as hyaluronic acid, and has the ability to draw water in the air and supply moisture to the epidermis. In particular, it is a natural moisturizing factor (NMF, Natural Moisturizing Factor) that absorbs moisture from the surrounding air. That is, it attracts moisture in the air to moisturize the scalp and hair, regulate the water content of the stratum corneum, and has a moisturizing ability of about 50% or more higher than that of glycerin. In addition, it makes hair elastic and supple, and protects hair from chemical damage such as physical damage or permits to soften the hair. It is preferred that the sodium PC contains 0.001-0.5% by weight of the composition.

또한, 본 발명은 상기한 성분들 이외의 통상의 탈모예방 성분, 발모 성분, 비듬방지 성분, 두피 가려움증 성분 등을 더 포함할 수 있는 것으로, 그 종류 및 함량을 제한하지 않는다.In addition, the present invention may further include conventional hair loss preventing ingredients, hair growth ingredients, anti-dandruff ingredients, scalp itching ingredients and the like other than the above-mentioned ingredients, and the kind and content thereof are not limited.

그리고 상기와 같은 성분들을 포함하는 본 발명의 조성물은, 헤어 샴푸, 헤어 앰플, 헤어 린스, 헤어 컨디셔너, 헤어 트리트먼트, 헤어 토닉, 헤어 로션, 헤어 크림 및 모발 영양화장수 중 어느 하나의 제형으로 제조될 수 있으며, 이들 각 제형의 조성물은 그 제형의 제제화에 필요하고 적절한 각종의 기제와 첨가물을 함유할 수 있으며, 이들 성분의 종류와 양은 당 업자에 의해 용이하게 선정될 수 있다.
The composition of the present invention comprising the above components may be prepared as a formulation of any one of hair shampoo, hair ampoule, hair conditioner, hair conditioner, hair treatment, hair tonic, hair lotion, hair cream, And the composition of each of these formulations may contain various kinds of bases and additives necessary for formulation of the formulations, and the kind and amount of these ingredients can be easily selected by those skilled in the art.

이하, 본 발명의 구체적인 실시예를 설명한다.Hereinafter, specific examples of the present invention will be described.

<실시예 1; 샴푸의 제조>&Lt; Example 1; Manufacture of shampoo>

하기 표 1과 같은 성분을 혼합하여 샴푸를 제조하였다.The ingredients as shown in Table 1 below were mixed to prepare a shampoo.

샴푸의 성분 및 조성비Composition and composition ratio of shampoo 성분명
/CAS.NO.
Ingredients
/CAS.NO.
조성비
(중량%)
Composition ratio
(weight%)
기능function 성분명
/CAS.NO.
Ingredients
/CAS.NO.
성비
(중량%)
Sex ratio
(weight%)
기능function
정제수(Water)
/7732-18-5
Purified Water
/ 7732-18-5
to.100to.100 SolventSolvent 창포추출물
/84775-39-3
Iris extract
/ 84775-39-3
0.5000.500 hair conditioning agentshair conditioning agents
암모늄라우릴설페이트액(Ammonium Lauryl Sulfate)
/2235-54-3
Ammonium Lauryl Sulfate (Ammonium Lauryl Sulfate)
/ 2235-54-3
35.00035,000 cleansing agentscleansing agents 멘톨(Menthol)
/89-78-1
Menthol
/ 89-78-1
0.3000.300 flavoring agentsflavoring agents
암모늄라우레스설페이트 (Ammonium Laureth Sulfate)
/32612-48-9
Ammonium Laureth Sulfate &lt; RTI ID = 0.0 &gt;
/ 32612-48-9
35.00035,000 cleansing agentscleansing agents 피록톤올아민( Piroctone Olamine) /68890-66-4 Piroctone Olamine / 68890-66-4 0.3000.300 preservativespreservatives
코카미도프로필베타인(Cocamidopropyl Betaine)
/61789-40-0
Cocamidopropyl Betaine &lt; RTI ID = 0.0 &gt;
/ 61789-40-0
8.0008.000 cleansing agentscleansing agents 살리실산(Salicylic Acid)
/69-72-7
Salicylic Acid
/ 69-72-7
0.2500.250 air conditioning agentsair conditioning agents
아모디메치콘/세트리모늄클로라이드/트리데세스-12(Amodimethicone/Cetrimonium Chloride/Trideceth-12)Amodimethicone / Cetrimonium Chloride / Trideceth-12 (Amodimethicone / Cetrimonium Chloride / Trideceth-12) 5.0005.000 cleansing agentscleansing agents 시트릭산(Citric Acid)
/77-92-9
Citric Acid
/ 77-92-9
0.2000.200 chelating agentschelating agents
피이지-12디메치콘(PEG-12 Dimethicone)PEG-12 dimethicone (PEG-12 dimethicone) 5.0005.000 cleansing agentscleansing agents 덱스판테놀(D-Panthenol) D-Panthenol 0.2000.200 hair conditioning agentshair conditioning agents 에탄올(Alcohol)
/64-17-5
Alcohol
/ 64-17-5
3.0003.000 SolventSolvent 폴리쿼터늄-10(Polyquaternium-10)
/53568-66-4
Polyquaternium-10 (Polyquaternium-10)
/ 53568-66-4
0.1500.150 film formersfilm formers
코카마이드디이에이(Cocamide DEA)
/61791-31-9
Cocamide DEA
/ 61791-31-9
2.0002.000 viscosity increasing agentsviscosity increasing agents 구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)
/65497-29-2
Guar Hydroxypropyltrimonium Chloride &lt; RTI ID = 0.0 &gt;
/ 65497-29-2
0.1000.100 hair conditioning agentshair conditioning agents
프로필렌글라이콜(Propylene Glycol)
/57-55-6
Propylene Glycol
/ 57-55-6
1.5001.500 cleansing agentscleansing agents 상백피추출물
/94167-05-2
Eucalyptus extract
/ 94167-05-2
0.1000 0.1000 hair conditioning agentshair conditioning agents
글라이콜디스테아레이트(Glycol Distearate)
/627-83-8
Glycol Distearate &lt; RTI ID = 0.0 &gt;
/ 627-83-8
1.0001,000 hair conditioning agentshair conditioning agents 병풀추출물
/84696-21-9
Centipede extract
/ 84696-21-9
0.1000 0.1000 hair conditioning agentshair conditioning agents
코카마이드엠이에이(Cocamide MEA)
/68140-00-1
Cocamide MEA
/ 68140-00-1
1.0001,000 preservativespreservatives 녹차추출물
/84650-60-2
Green tea extract
/ 84650-60-2
0.1000 0.1000 hair conditioning agentshair conditioning agents
DL-판테놀(DL-Panthenol)DL-Panthenol (DL-Panthenol) 0.5000.500 hair conditioning agentshair conditioning agents 쑥추출물
/84775-45-1
Mugwort extract
/ 84775-45-1
0.1000 0.1000 hair conditioning agentshair conditioning agents
페녹시에탄올(Phenoxyethanol)
/122-99-6
Phenoxyethanol
/ 122-99-6
0.5000.500 hair conditioning agentshair conditioning agents 의이인추출물Wii extract 0.1000 0.1000 hair conditioning agentshair conditioning agents
서양장미꽃추출물
/84604-12-6
Western rose flower extract
/ 84604-12-6
0.5000.500 hair conditioning agentshair conditioning agents 천궁추출물Cinnabar extract 0.1000 0.1000 hair conditioning agentshair conditioning agents
하이드롤라이즈드케라틴( Hydrolyzed Keratin)
/69430-36-0
Hydrolyzed Keratin &lt; RTI ID = 0.0 &gt;
/ 69430-36-0
0.5000.500 hair conditioning agentshair conditioning agents 히아루론산( Hyaluronic Acid)
/9004-61-9
Hyaluronic Acid
/ 9004-61-9
0.1000 0.1000 hair conditioning agentshair conditioning agents
하이드롤라이즈드콜라겐( Hydrolyzed Collagen)
/73049-73-7
Hydrolyzed collagen
/ 73049-73-7
0.5000 0.5000 hair conditioning agentshair conditioning agents 바이오틴(Biotin)
/58-85-5
Biotin
/ 58-85-5
0.0600.060 hair conditioning agentshair conditioning agents
폴리쿼터늄-92( Polyquaternium-92 )
/42492-22-8
Polyquaternium-92 (Polyquaternium-92)
/ 42492-22-8
0.5000 0.5000 hair conditioning agentshair conditioning agents 디소듐이디티에이
(Disodium EDTA)
/139-33-3
Disodium iodide
(Disodium EDTA)
/ 139-33-3
0.0500.050 chelating agentschelating agents
하이드롤라이즈드실크( Hydrolyzed Silk)
/73049-73-7
Hydrolyzed Silk
/ 73049-73-7
0.5000 0.5000 hair conditioning agentshair conditioning agents 향료Spices 0.0500.050 FragranceFragrance

<실시예 2; 토닉의 제조>&Lt; Example 2; Manufacture of tonics>

하기 표 2와 같은 성분을 혼합하여 토닉을 제조하였다.The tonics were prepared by mixing the ingredients as shown in Table 2 below.

토닉의 성분 및 조성비Tonic composition and composition ratio 성분명
/CAS.NO.
Ingredients
/CAS.NO.
조성비
(중량%)
Composition ratio
(weight%)
기능function 성분명
/CAS.NO.
Ingredients
/CAS.NO.
조성비
(중량%)
Composition ratio
(weight%)
기능function
정제수(Water)
/7732-18-5
Purified Water
/ 7732-18-5
to.100to.100 SolventSolvent 디소듐이디티에이(Disodium EDTA)
/139-33-3
Disodium EDTA &lt; RTI ID = 0.0 &gt;
/ 139-33-3
0.0200.020 chelating agentschelating agents
에탄올(Alcohol)
/64-17-5
Alcohol
/ 64-17-5
20.00020,000 SolventSolvent 피록톤올아민( Piroctone Olamine)
/68890-66-4
Piroctone Olamine
/ 68890-66-4
0.0030.003 preservativespreservatives
DL-판테놀(DL-Panthenol)DL-Panthenol (DL-Panthenol) 1.5001.500 hair conditioning agentshair conditioning agents 하이드롤라이즈드케라틴( Hydrolyzed Keratin)
/69430-36-0
Hydrolyzed Keratin &lt; RTI ID = 0.0 &gt;
/ 69430-36-0
0.0010.001 hair conditioning agentshair conditioning agents
페녹시에탄올(Phenoxyethanol)
/122-99-6
Phenoxyethanol
/ 122-99-6
0.8000.800 preservativespreservatives 하이드롤라이즈드콜라겐( Hydrolyzed Collagen)
/73049-73-7
Hydrolyzed collagen
/ 73049-73-7
0.0010.001 hair conditioning agentshair conditioning agents
폴리소르베이트20(Polysorbate 20)
/9005-64-5
Polysorbate 20 (Polysorbate 20)
/ 9005-64-5
0.6000.600 surfactantssurfactants 하이드롤라이즈드실크( Hydrolyzed Silk)
/73049-73-7
Hydrolyzed Silk
/ 73049-73-7
0.0010.001 hair conditioning agentshair conditioning agents
파마자기름,수소화된,에톡시산화된( ASTOR OIL, HYDROGENATED, ETHOXYLATED )
/61788-85-0
Hydrogenated, ethoxylated (ASTOR OIL, HYDROGENATED, ETHOXYLATED)
/ 61788-85-0
0.5000.500 hair conditioning agentshair conditioning agents 녹차추출물
/84650-60-2
Green tea extract
/ 84650-60-2
0.0010.001 hair conditioning agentshair conditioning agents
멘톨(Menthol)
/89-78-1
Menthol
/ 89-78-1
0.3000.300 flavoring agentsflavoring agents 상백피추출물
/94167-05-2 0.001
Eucalyptus extract
/ 94167-05-2 0.001
0.0010.001 hair conditioning agentshair conditioning agents
살리실산(Salicylic Acid)
/69-72-7
Salicylic Acid
/ 69-72-7
0.2500.250 hair conditioning agentshair conditioning agents 병풀추출물
/84696-21-9
Centipede extract
/ 84696-21-9
0.0010.001 hair conditioning agentshair conditioning agents
덱스판테놀(D-Panthenol)D-Panthenol 0.2000.200 hair conditioning agentshair conditioning agents 쑥추출물
/84775-45-1
Mugwort extract
/ 84775-45-1
0.0010.001 hair conditioning agentshair conditioning agents
서양장미꽃추출물 Western rose flower extract 0.2000.200 hair conditioning agentshair conditioning agents 의이인추출물Wii extract 0.0010.001 hair conditioning agentshair conditioning agents 알란토인(Allantoin)
/97-59-6
Allantoin
/ 97-59-6
0.1000.100 hair conditioning agentshair conditioning agents 천궁추출물Cinnabar extract 0.0010.001 hair conditioning agentshair conditioning agents
나이아신아마이드(Niacinamide)
/98-92-0
Niacinamide
/ 98-92-0
0.1000.100 hair conditioning agentshair conditioning agents 창포추출물
/84775-39-3
Iris extract
/ 84775-39-3
0.0010.001 hair conditioning agentshair conditioning agents
디포타슘글리시리제이트(Dipotassium Glycyrrhizate)Dipotassium Glycyrrhizate &lt; RTI ID = 0.0 &gt; 0.1000.100 hair conditioning agentshair conditioning agents 카라멜색소
/8028-89-5
Caramel color
/ 8028-89-5
0.0010.001 colorantscolorants
소듐시트레이트(Sodium Citrate)
/1968-04-02
Sodium Citrate
/ 1968-04-02
0.1000.100 chelating agentschelating agents

<실시예 3; 앰플의 제조>&Lt; Example 3; Manufacture of ampoules>

하기 표 3과 같은 성분을 혼합하여 앰플을 제조하였다.Ampoules were prepared by mixing the ingredients shown in Table 3 below.

앰플의 성분 및 조성비Composition and composition ratio of ampoule 성분명
/CAS.NO.
Ingredients
/CAS.NO.
조성비
(중량%)
Composition ratio
(weight%)
기능function 성분명
/CAS.NO.
Ingredients
/CAS.NO.
조성비
(중량%)
Composition ratio
(weight%)
기능function
정제수(Water)
/7732-18-5
Purified Water
/ 7732-18-5
to.100to.100 SolventSolvent 소듐피씨에이( Sodium PCA)
/28874-51-3
Sodium PCA
/ 28874-51-3
0.6000.600 hair conditioning agentshair conditioning agents
에탄올(Alcohol)
/64-17-5
Alcohol
/ 64-17-5
20.00020,000 SolventSolvent 페녹시에탄올(Phenoxyethanol)
/122-99-6
Phenoxyethanol
/ 122-99-6
0.5000.500 preservativespreservatives
DL-판테놀(DL-Panthenol)DL-Panthenol (DL-Panthenol) 1.5001.500 hair conditioning agentshair conditioning agents 하이드롤라이즈드케라틴( Hydrolyzed Keratin)
/69430-36-0
Hydrolyzed Keratin &lt; RTI ID = 0.0 &gt;
/ 69430-36-0
0.1000.100 hair conditioning agentshair conditioning agents
부틸렌글라이콜 (Butylene Glycol)
/107-88-0
Butylene Glycol
/ 107-88-0
1.0001,000 SolventSolvent 하이드롤라이즈드콜라겐( Hydrolyzed Collagen)
/73049-73-7
Hydrolyzed collagen
/ 73049-73-7
0.1000.100 hair conditioning agentshair conditioning agents
폴리소르베이트20(Polysorbate 20)
/9005-64-5
Polysorbate 20 (Polysorbate 20)
/ 9005-64-5
0.9000.900 surfactantssurfactants 하이드롤라이즈드실크( Hydrolyzed Silk)
/73049-73-7
Hydrolyzed Silk
/ 73049-73-7
0.1000.100 hair conditioning agentshair conditioning agents
노녹시놀-12( Nonoxynol-12)
/9016-45-9
Nonoxynol-12 &lt; / RTI &gt;
/ 9016-45-9
0.9000.900 surfactantssurfactants 녹차추출물
/84650-60-2
Green tea extract
/ 84650-60-2
0.1000.100 hair conditioning agentshair conditioning agents
멘톨(Menthol)
/89-78-1
Menthol
/ 89-78-1
0.3000.300 flavoring agentsflavoring agents 상백피추출물
/94167-05-2 0.001
Eucalyptus extract
/ 94167-05-2 0.001
0.1000.100 hair conditioning agentshair conditioning agents
살리실산(Salicylic Acid)
/69-72-7
Salicylic Acid
/ 69-72-7
0.2500.250 hair conditioning agentshair conditioning agents 병풀추출물
/84696-21-9
Centipede extract
/ 84696-21-9
0.1000.100 hair conditioning agentshair conditioning agents
덱스판테놀(D-Panthenol)D-Panthenol 0.2000.200 hair conditioning agentshair conditioning agents 쑥추출물
/84775-45-1
Mugwort extract
/ 84775-45-1
0.1000.100 hair conditioning agentshair conditioning agents
서양장미꽃추출물 Western rose flower extract 0.1500.150 hair conditioning agentshair conditioning agents 의이인추출물Wii extract 0.1000.100 hair conditioning agentshair conditioning agents 알란토인(Allantoin)
/97-59-6
Allantoin
/ 97-59-6
0.1000.100 hair conditioning agentshair conditioning agents 천궁추출물Cinnabar extract 0.1000.100 hair conditioning agentshair conditioning agents
히알루론산(Hyaluronic Acid)
/73049-73-7
Hyaluronic Acid
/ 73049-73-7
0.1000.100 hair conditioning agentshair conditioning agents 창포추출물
/84775-39-3
Iris extract
/ 84775-39-3
0.1000.100 hair conditioning agentshair conditioning agents
소듐시트레이트(Sodium Citrate)
/1968-04-02
Sodium Citrate
/ 1968-04-02
0.1000.100 chelating agentschelating agents 디소듐이디티에이(Disdium EDTA)
/139-33-3
Disodium EDTA &lt; RTI ID = 0.0 &gt;
/ 139-33-3
0.0100.010 chelating agentschelating agents

상기 실시예 1, 2, 3에서의 천연재 추출물은 물과 에탄올을 1:1 부피비로 혼합한 혼합용매를 이용하여, 60~90℃에서 추출용매에 천연재를 넣고 환류하여 추출하였다.The thunder seaweed extracts of Examples 1, 2 and 3 were prepared by mixing a mixture of water and ethanol in a volume ratio of 1: 1 by volume and then extracting the extract by refluxing at 60 to 90 ° C.

그리고 본 발명의 비교예 1, 2, 3으로서, 실시예 1, 2, 3과 동일하게 실시하되, 서양장미꽃추출물, 녹차추출물, 상백피추출물, 병풀추출물, 쑥추출물, 의이인추출물, 천궁추출물, 창포추출물을 혼합하지 않았다. As Comparative Examples 1, 2 and 3 of the present invention, the same procedures as in Examples 1, 2 and 3 were carried out, except that the extracts of western rose flower, green tea extract, manganese extract, mulberry leaf extract, mugwort extract, The extracts were not mixed.

본 발명의 비교예 4, 5, 6으로서, 실시예 1, 2, 3과 동일하게 실시하되, 서양장미꽃추출물, 녹차추출물, 상백피추출물, 병풀추출물을 혼합하지 않았다. As Comparative Examples 4, 5, and 6 of the present invention, the same procedures as in Examples 1, 2, and 3 were carried out, but the western rose flower extract, green tea extract, manganese berry extract and centilla callus extract were not mixed.

또한, 비교예 7로서 미녹시딜을 준비하였다.
In addition, as Comparative Example 7, minoxidil was prepared.

(실험예 1)(Experimental Example 1)

본 발명의 조성물로 두피 가려움증이 있는 대상자를 선정하여 테스트를 실시하였다. 피험자는 35-50세까지의 두피 가려움증이 있는 성인남녀 총 40명을 대상으로 1일 1회, 상기 실시예 1의 샴푸를 이용하여 머리를 감은 후, 상기 실시예 2의 컨디셔닝 5ml, 실시예 3의 앰플 7ml를 3개월간 사용하여 그 결과를 관찰하였다. 상기 비교예 7은 정해진 사용법과 함량에 따라 3개월간 사용하였다.(한 그룹은 남성 5명, 여성 5명으로 하였다.)Subjects who had scalp itching were selected and tested by the composition of the present invention. The subjects were 40 adult male and female subjects with scalp itching up to 35-50 years of age. The hair was wound once a day using the shampoo of Example 1, followed by conditioning 5 ml of Example 2, Example 3 Of ampoule was used for 3 months and the result was observed. The comparative example 7 was used for 3 months according to the prescribed usage and content (one male and five female).

효과의 판정은 가려움증 완화 정도 및 자극에 대한 느낌을 평가척도로서 5단계로 평가하고, 상기 평가 척도의 평균으로 하였는데, 그 점수는 5점 만점으로 단계에 따라 1점 단위로 부여하였다.
The evaluation of the effect was made by evaluating the degree of the itching relief and the feeling of the stimulus as an evaluation scale in five levels and an average of the evaluation scale.

실험예 1의 테스트 결과.Test result of Experimental Example 1. 구분division 실시예 1, 2, 3
사용 그룹
Examples 1, 2, and 3
Usage group
비교예 1, 2, 3
사용 그룹
Comparative Examples 1, 2, and 3
Usage group
비교예 4, 5, 6
사용 그룹
Comparative Examples 4, 5 and 6
Usage group
비교예 7
사용 그룹
Comparative Example 7
Usage group
가려움증 완화효과Itching relief effect 4.24.2 2.52.5 2.82.8 2.22.2 자극평가Evaluation of stimulation 1.21.2 1.31.3 1.51.5 3.03.0 1: 효과 또는 자극이 전혀 없다. 2: 효과 또는 자극이 없는 편이다. 3: 효과 또는 자극이 보통이다. 4: 효과 또는 자극이 있다. 5: 효과 또는 자극이 많이 있다.1: There is no effect or irritation at all. 2: There is no effect or irritation. 3: The effect or stimulus is normal. 4: There is an effect or irritation. 5: There are many effects or stimuli.

상기 표 4에서 확인할 수 있는 바와 같이, 본 발명의 실시예 1, 2, 3을 사용한 그룹이 가려움증 완화효과가 비교예들에 비해 우수하였으며, 자극 정도는 큰 차이가 없었다.
As can be seen in Table 4, the groups using Examples 1, 2 and 3 of the present invention were superior to the comparative examples in mitigating itching, and there was no significant difference in the degree of stimulation.

(실험예 2)(Experimental Example 2)

본 발명의 조성물로 탈모증이 있는 대상자를 선정하여 테스트를 실시하였다.Subjects who had alopecia were selected and tested by the composition of the present invention.

피험자는 35-50세까지의 탈모증이 있는 성인남녀 총 50명을 대상으로 1일 1회, 상기 실시예 1의 샴푸를 이용하여 머리를 감은 후, 상기 실시예 2의 컨디셔닝 5ml, 실시예 3의 앰플 7ml를 3개월간 사용하여 그 결과를 관찰하였다. 상기 비교예 7은 정해진 사용법과 함량에 따라 3개월간 사용하였다.(한 그룹은 남성 5명, 여성 5명으로 하였다.)The subjects were a total of 50 adult male and female subjects with alopecia ranging from 35 to 50 years old. The hair was wound once a day using the shampoo of Example 1, and then the conditioned 5 ml of Example 2, 7 ml of ampoule was used for 3 months and the result was observed. The comparative example 7 was used for 3 months according to the prescribed usage and content (one male and five female).

효과의 판정은 세발시 일일 평균 탈모량, 육안판정소견 및 자각증상 개선 정도를 평가척도로써 5단계로 평가하고 종합적인 개선도를 상기 평가 척도의 평균으로 하였는데, 그 점수는 5점 만점으로 단계에 따라 1점 단위로 부여하였다.
The efficacy was assessed in five steps as an evaluation scale, and the overall improvement was evaluated as the average of the evaluation scale. The score was 5 points And was given in units of 1 point.

실험예 2의 테스트 결과.Test result of Experimental Example 2. 구분division 실시예 1, 2, 3 사용 그룹Examples 1, 2, and 3 Use groups 비교예 1, 2, 3
사용 그룹
Comparative Examples 1, 2, and 3
Usage group
비교예 4, 5, 6
사용 그룹
Comparative Examples 4, 5 and 6
Usage group
비교예 7
사용 그룹
Comparative Example 7
Usage group
육안Visually 3.53.5 2.52.5 2.72.7 2.52.5 자각증상Subjective symptoms 3.93.9 2.32.3 2.92.9 2.12.1 세발시 탈모수Number of hair loss 3.73.7 2.42.4 2.72.7 2.32.3 종합개선Comprehensive improvement 3.93.9 2.52.5 2.82.8 2.22.2 1: 악화, 2: 불변, 3: 조금 개선, 4: 중간 개선, 5:많이 개선1: worse, 2: unchanged, 3: slight improvement, 4: moderate improvement, 5: much improvement

상기 표 5에서 확인할 수 있는 바와 같이, 본 발명의 실시예들을 사용한 그룹이 육안, 자각증상, 탈모수, 종합개선에서 모두 비교예들의 사용 그룹보다 현저히 좋은 점수를 받아 우수한 탈모 개선효과를 보임을 확인할 수 있었다.
As can be seen from the above Table 5, it was confirmed that the group using the examples of the present invention showed significantly better scores than the use groups of the comparative examples in terms of visual acuity, subjective symptoms, number of hair loss, I could.

(실험예 3)(Experimental Example 3)

실시예 1, 2, 3에 대한 사용감을 테스트하였다.The feeling for Examples 1, 2 and 3 was tested.

피험자는 25-35세까지의 긴 생머리인 성인 여성 총 30명을 대상으로 1일 1회, 상기 실시예 1의 샴푸를 이용하여 머리를 감은 후, 상기 실시예 2의 컨디셔닝 5ml, 실시예 3의 앰플 7ml를 사용하여 그 결과를 관찰하였다.(첫째날 실시예 1, 2, 3을 사용토록 하였으며, 일주일간 자신이 사용하던 제품을 사용하여 샴푸한 후, 비교예 1, 2, 3을 사용토록 하였고, 다시 일주일간 자신이 사용하던 제품을 사용하여 샴푸한 후, 비교예 4, 5, 6을 사용토록 하였다)The subject was a 30-day-old adult female of 25-35 years of age. The hair was wound once a day by using the shampoo of Example 1, and then the conditioning of 5 ml of Example 2 and that of Example 3 The results were observed using 7 ml of ampoule. (On the first day, Examples 1, 2, and 3 were used. After one week of shampooing using the product they were using, Comparative Examples 1, 2, and 3 were used , Shampooed again using the products he used for one week, and then Comparative Examples 4, 5 and 6 were used)

효과의 판정은 기포성, 윤기, 매끄러움, 사용 시 촉감, 사용 후 촉감, 건조 후 촉감, 건조 후 빗질감에 대한 만족도를 평가하게 하였다. 평가척도로서 5단계로 평가하고, 그 평균으로 결과를 나타내었으며, 그 점수는 5점 만점으로 단계에 따라 1점 단위로 부여하였다.
The evaluation of the effect was made to evaluate the satisfaction with foaminess, luster, smoothness, feeling on use, feel after use, touch after drying, and combing after drying. The evaluation scale was evaluated in five steps, and the results were shown as an average. The scores were given in units of one point in five steps.

실험예 3의 테스트 결과.Test results of Experimental Example 3. 구분division 실시예 1, 2, 3 사용 그룹Examples 1, 2, and 3 Use groups 비교예 1, 2, 3
사용 그룹
Comparative Examples 1, 2, and 3
Usage group
비교예 4, 5, 6
사용 그룹
Comparative Examples 4, 5 and 6
Usage group
기포성Bubble 3.83.8 3.73.7 3.83.8 윤기burnish 4.24.2 2.52.5 3.23.2 매끄러움lubricity 4.34.3 2.92.9 3.53.5 사용 시 촉감Tactile feeling 4.24.2 2.92.9 3.33.3 건조 후 촉감After the dry touch 4.34.3 3.03.0 3.43.4 1: 많이 좋지 않음, 2: 조금 좋지 않음, 3: 보통, 4: 조금 좋음, 5:많이 좋음1: Very bad, 2: Bad, 3: Fair, 4: Good, 5: Very good

상기 표 6에서 확인할 수 있는 바와 같이, 윤기, 매끄러움, 촉감면에서 본 발명의 실시예들을 사용한 그룹이 비교예들을 사용한 그룹보다 확연히 높은 점수를 받았음을 확인할 수 있었다.
As can be seen from the above Table 6, it was confirmed that the group using the embodiments of the present invention in terms of glossiness, smoothness, and tactility received a significantly higher score than the group using the comparative examples.

상기한 실시예들을 통해 알 수 있는 바와 같이, 본 발명의 조성물은 탈모예방, 발모 등의 효과를 갖는 것은 물론, 두피 가려움증 등을 개선하고, 모발의 윤기, 촉감 역시 개선하는 것으로, 다양한 제형으로서 활용이 가능하다. 아울러, 천연재 추출물을 이용함으로써, 장기간 사용하더라도 인체에 안정적이라는 장점이 있다.
As can be seen from the above examples, the composition of the present invention not only has effects of hair loss prevention, hair growth, etc., but also improves scalp itching and the like, and also improves hair gloss and touch. This is possible. In addition, the use of a ginseng extract has the advantage that it is stable to the human body even when it is used for a long time.

이상과 같이, 본 발명은 비록 한정된 실시예와 도면에 의해 설명되었으나, 본 발명은 이것에 의해 한정되지 않으며 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자에 의해 본 발명의 기술 사상과 아래에 기재될 특허 청구범위의 균등 범위 내에서 다양한 수정 및 변형이 가능함은 물론이다.While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. It will be understood that various modifications and changes may be made without departing from the scope of the appended claims.

Claims (6)

삭제delete 삭제delete 삭제delete 조성물 전체에 대하여 서양장미꽃추출물 0.1~0.5중량%, 창포추출물 0.001~0.15중량%, 상백피추출물 0.001~0.15중량%, 병풀추출물 0.001~0.15중량%, 녹차추출물 0.001~0.15중량%, 쑥추출물 0.001~0.15중량%, 의이인추출물 0.001~0.15중량%, 천궁추출물 0.001~0.15중량%, 하이드롤라이즈드케라틴(Hydrolyzed Keratin) 0.001~0.5중량%, 하이드롤라이즈드콜라겐(Hydrolyzed Collagen) 0.001~0.5중량%, 하이드롤라이즈드실크(Hydrolyzed Silk) 0.001~0.5중량%, 멘톨(Menthol) 0.3중량%, 살리실산(Salicylic Acid) 0.25중량% 및 덱스판테놀(D-Panthenol) 0.2중량%를 유효성분으로 포함하며,
상기 추출물은 물, 알코올, 탄화수소계 용매 및 비극성 유기용매 이루어진 군 중 선택된 1종 이상의 용매를 사용하여 추출된 것임을 특징으로 하는 두피 및 모발 상태 개선용 조성물.
0.001 to 0.15% by weight of the extract of Curcuma bark extract, 0.001 to 0.15% by weight of the centipede extract, 0.001 to 0.15% by weight of green tea extract, 0.001 to 0.15% by weight of green tea extract, 0.001 to 0.15% by weight of the extract of Uisin, 0.001 to 0.15% by weight of the extract of Chenopodium ambrosioides, 0.001 to 0.5% by weight of hydrolyzed keratin, 0.001 to 0.5% by weight of hydrolyzed collagen, Wherein the active ingredient comprises 0.001 to 0.5% by weight of hydrolyzed silk, 0.3% by weight of menthol, 0.25% by weight of salicylic acid and 0.2% by weight of D-Panthenol,
Wherein the extract is extracted using at least one solvent selected from the group consisting of water, an alcohol, a hydrocarbon-based solvent and a nonpolar organic solvent.
제 4항에 있어서,
나이아신아마이드(Niacinamide), 하이알루론산(Hyaluronic acid), 소듐피씨에이(Sodium Pyrrolidone Carboxylic acid)로 이루어진 군 중 선택된 1종 이상의 것을 추가로 포함하는 것을 특징으로 하는 두피 및 모발 상태 개선용 조성물.
5. The method of claim 4,
A composition for improving scalp and hair condition characterized by further comprising at least one selected from the group consisting of Niacinamide, Hyaluronic acid, and Sodium Pyrrolidone Carboxylic acid.
제 4항 또는 제 5항에 있어서,
상기 조성물의 제형은 헤어 샴푸, 헤어 앰플, 헤어 린스, 헤어 컨디셔너, 헤어 트리트먼트, 헤어 토닉, 헤어 로션, 헤어 크림 및 모발 영양화장수 중 어느 하나인 것을 특징으로 하는 두피 및 모발 상태 개선용 조성물.
The method according to claim 4 or 5,
Wherein the composition is one of a hair shampoo, a hair ampule, a hair conditioner, a hair conditioner, a hair treatment, a hair tonic, a hair lotion, a hair cream, and a hair nutrition lotion.
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