CN109745262B - Composition for whitening spot-fading face cream - Google Patents
Composition for whitening spot-fading face cream Download PDFInfo
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- CN109745262B CN109745262B CN201910216868.8A CN201910216868A CN109745262B CN 109745262 B CN109745262 B CN 109745262B CN 201910216868 A CN201910216868 A CN 201910216868A CN 109745262 B CN109745262 B CN 109745262B
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Abstract
The invention relates to the technical field of cosmetics, in particular to a composition for whitening spot-lightening cream and a preparation method thereof. The invention provides a composition for whitening spot-lightening cream, which comprises a phase A, a phase B, a phase C, a phase D and water; wherein, the phase A component comprises a thickening agent, a functional additive, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium; the B phase component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate; the C phase component comprises polyacrylate-13, polyisobutylene and polysorbate-20; the phase D component comprises panthenol and xylitol substances.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a composition for whitening spot-lightening cream and a preparation method thereof.
Background
With the improvement of living standard, beauty and skin care are more and more emphasized, the requirements of people on the efficacy and safety of skin care products are higher and higher, and facial color spots and facial roughness caused by heredity, ultraviolet irradiation or other reasons also become problems which plague people of all ages.
The skin care products are always well received by the great female love, and various skin care product types such as facial cleanser (cream/ointment), skin lotion, toner, face cream, mascara and the like appear on the market. For a single product, manufacturers also develop different functional products, such as whitening, freckle removing, moisturizing, oil control and the like.
The facial stain is a pigmentation dermatosis which occurs on the face, belongs to the categories of liver spots, face dust and the like in the traditional Chinese medicine, and is more common in terms of chloasma and freckles. The traditional Chinese medicine considers that the facial color spots are mostly caused by liver depression and qi stagnation, blood heat and blood stasis, or spleen deficiency which can not generate essence and micro, qi and blood deficiency, skin malnutrition, kidney water which can not control fire, deficiency heat in the interior and skin stagnation. Western medicine believes that it is primarily due to melanin deposition, whereas tyrosinase is the primary enzyme in the formation of melanin. The facial color spots are clinically manifested as yellow exhausted color, light exhausted color, dark brown spots or diffuse spots. Irregular shapes and unclear boundaries are better on the cheeks, forehead, nose, face or around the ears, lips, and some spread over the face and even around the neck.
Various heavy metal compounds such as mercury compounds added in the whitening cosmetics in the prior art can destroy the formation of epidermal enzymes from the mechanism due to extremely strong complex forming capability, so that the formation of melanin is inhibited, and the whitening effect is achieved, and the products are easy to cause cancers after long-term use; part of the lead-containing compound plays a role in visual whitening through covering; some products also use strong oxidants to whiten the skin surface layer in modes of bleaching, excessively removing cutin and the like, and the skin is chronically damaged in the past, so that the research and development of a safe and effective whitening and spot-fading product is one of the key points of the research and development of cosmetics. Therefore, the preparation of the safe and efficient multifunctional whitening spot-fading cream is very important.
Disclosure of Invention
In order to solve the above problems, a first aspect of the present invention provides a composition for whitening spot-lightening cream, comprising phase a, phase B, phase C, phase D components and water; wherein, the phase A component comprises a thickening agent, a functional additive, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium; the B phase component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate; the C phase component comprises polyacrylate-13, polyisobutylene and polysorbate-20; the phase D component comprises panthenol and xylitol substances.
The invention relates to a preferable technical scheme, wherein the composition comprises, by weight, 0.13-40% of phase A component, 0.8-43% of phase B component, 0.1-7.0% of phase C component, 0.1-8.0% of phase D component and the balance of water.
As a preferable embodiment of the present invention, the thickener includes a first component, a second component, a third component, and a fourth component; wherein the first component comprises arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside, the second component comprises oleyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol and cetyl alcohol, the third component comprises glyceryl stearate and PEG-100 stearate, and the fourth component comprises cetyl alcohol and cetyl ethyl hexanoate.
The preferable technical scheme of the invention is that the weight ratio of the first component to the second component to the third component to the fourth component is (0.5-3.0): (0.2-5.0): (0.1-3.0): (0.2-17.0).
As a preferable technical scheme of the invention, the xylitol substances comprise xylitol-based glucoside, dehydrated xylitol and xylitol.
In a preferred embodiment of the present invention, the functional adjuvant comprises pepper seed extract, p-hydroxyacetophenone, hydrogenated polyisobutene, and dodecanoylphenylalanine.
As a preferable technical scheme of the invention, the weight ratio of the thickening agent, the functional auxiliary agent, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium in the phase A component is (1.0-28): (0.2-13): (0.1-6.0): (0.01-1.0): (0.01-0.6): (0.01-1.0).
In a preferable embodiment of the present invention, the weight ratio of the alcohol substance, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate in the phase B component is (0.3-30): (0.1-1.0): (0.1-4.0): (0.1-10): (0.1-6.0): (0.1-7.0).
The second aspect of the invention provides a preparation method of the composition of the whitening and spot-lightening cream, which comprises the following steps:
(1) adding the substances in the component A into an oil phase pot, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component in the step 2, and uniformly mixing;
(4) cooling, adding the C phase component, and uniformly stirring;
(5) cooling, adding the phase D component, and stirring to obtain the cream composition.
The third aspect of the invention provides a whitening and spot-lightening cream, and a composition containing the whitening and spot-lightening cream.
The invention has the beneficial effects that: the whitening and spot-fading cream provided by the invention can effectively improve the whitening effect of skin, eliminate the spot-fading of face, promote wound healing and treat inflammation; in addition, the composition has good appearance, proper viscosity, easy spreading and good fineness, does not present a flowing emulsion state, is easy to smear and absorb by facial skin, does not cause phenomena of allergy and the like, and enlarges the application range of the product; on the other hand, the composition provided by the invention has good stability and is easy to store.
Detailed Description
In order to solve the technical problems, the invention provides a composition for whitening spot-lightening cream, which comprises a phase A, a phase B, a phase C, a phase D and water; wherein, the phase A component comprises a thickening agent, a functional additive, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium; the B phase component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate; the C phase component comprises polyacrylate-13, polyisobutylene and polysorbate-20; the phase D component comprises panthenol and xylitol substances.
In one embodiment, the composition for whitening spot-lightening cream comprises 0.13-40% of phase A component, 0.8-43% of phase B component, 0.1-7.0% of phase C component, 0.1-8.0% of phase D component and the balance of water in percentage by weight; preferably, the composition for whitening and spot-lightening cream comprises 15-35% of phase A component, 20-40% of phase B component, 2.0-5.0% of phase C component, 2.0-6.0% of phase D component and the balance of water; more preferably, the composition for whitening spot-lightening cream comprises 30% of phase A component, 35% of phase B component, 3.5% of phase C component, 4.5% of phase D component and the balance of water.
In one embodiment, the thickener comprises a first component, a second component, a third component, and a fourth component; wherein the first component comprises arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside, the second component comprises oleyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol and cetyl alcohol, the third component comprises glyceryl stearate and PEG-100 stearate, and the fourth component comprises cetyl alcohol and cetyl ethyl hexanoate.
In one embodiment, the weight ratio of the first component, the second component, the third component and the fourth component is (0.5-3.0): (0.2-5.0): (0.1-3.0): (0.2 to 17.0); preferably, the weight ratio of the first component to the second component to the third component to the fourth component is (1.0-2.0): (1.0-4.0): (1.0-2.5): (5-10); more preferably, the weight ratio of the first component, the second component, the third component and the fourth component is 1.5: 2.5: 2.0: 13.
in one embodiment, the weight ratio of arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside in the first component is 1: (0.5-3): (1-3); preferably, the weight ratio of arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside is 1: 2.2: 1.8.
in one embodiment, the weight ratio of the stearyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol, and cetyl alcohol in the second component is 1: (0.5-2): (0.5-2): (0.5-2): (1-3): (1-3): (1-3): (0.8-2.5); preferably, the weight ratio of the oleostearyl alcohol, the behenyl alcohol, the palmitic acid, the stearic acid, the lecithin, the lauryl alcohol, the myristyl alcohol and the cetyl alcohol is 1: 1.3: 1.5: 1.5: 2.0: 2.0: 2.1: 1.6.
in one embodiment, the weight ratio of glyceryl stearate to PEG-100 stearate in the third component is 1: (0.8-2.5); preferably, the weight ratio of glyceryl stearate to PEG-100 stearate is 1: 1.25.
in one embodiment, the weight ratio of cetyl stearate alcohol to cetyl ethylhexanoate in the fourth component is (0.1-7.0): (0.1-10.0); preferably, the weight ratio of cetyl stearyl alcohol to cetyl ethylhexanoate is 1: 5.
trisodium ascorbyl palmitate phosphate:
the trisodium ascorbyl palmitate phosphate can promote the synthesis of ceramide on the skin and increase the softness and the moistening degree of the skin; meanwhile, the trisodium ascorbyl palmitate phosphate is a water-soluble vitamin C derivative, can penetrate through the skin and is converted into free vitamin C under the action of enzymes in the skin, and is also favorable for promoting collagen synthesis, inhibiting collagen decomposition and improving skin aging.
Caprylic capric triglyceride:
the caprylic/capric triglyceride is high-purity oil prepared by esterifying caprylic/capric acid and glycerol. It is an excellent moisturizing grease, which makes the skin feel smooth but not greasy and is easy to be absorbed by the skin; the skin care cream plays a good role in the uniformity and fineness of cosmetics and enables the skin to be smooth and glossy; the caprylic/capric triglyceride can be used as base material of moisturizing factor, cosmetic stabilizer, antifreezing agent, and homogenizing agent.
The caprylic/capric triglyceride is clear to light yellow, is high-clear odorless grease, and belongs to the derivatives of palm oil or coconut oil; it is extracted by a thermal fractionation method; because of the compatible characteristics with human skin, the skin care oil is also suitable for oily skin, and pores cannot be blocked; it has non-greasy texture, can be added into cream or lotion to improve extensibility, and has effects of lubricating and softening skin, and has function of filtering ultraviolet light.
The caprylic/capric triglyceride has stable storage property, and can be stored for more than 6 months after unsealing, and proper storage conditions such as low temperature storage and avoidance of direct contact with sunlight are also required.
Jojoba seed oil:
jojoba seed oil is a common component in skin care products, is a substance obtained by cold pressing and oil pressing treatment, is easy to absorb by a human body because molecules contained in the jojoba seed oil are very close to sebum of the human body, and can help the skin to solve the problems of dry, water-deficient, rough, dark and other skin defects.
In one embodiment, the functional adjuvants include pepper seed extract, p-hydroxyacetophenone, hydrogenated polyisobutene, and dodecanoylphenylalanine; preferably, the weight ratio of the pepper seed extract to the p-hydroxyacetophenone to the hydrogenated polyisobutene to the dodecanoylphenylalanine is (0.01-0.5): (0.1-0.8): (0.1-10.0): (0.01-1.0); more preferably, the weight ratio of the pepper seed extract, the p-hydroxyacetophenone, the hydrogenated polyisobutene, and the dodecanoylphenylalanine is 0.25: 0.45: 5.5: 0.45.
p-hydroxyacetophenone:
p-Hydroxyacetophenone (p-Hydroxyacetophenone) is also called 4-Hydroxyacetophenone (4-Hydroxyacetophenone), 4-Acetylphenol (4-Acetylphenol), p-Acetylphenol (p-Acetylphenol), 4-hydroxyphenylmethyl ketone (4-hydroxyphenylmethyl ketone), commonly called conicol (picenol), is white needle-shaped crystal at normal temperature, is combustible and easily soluble in hot water, methanol, ethanol, ether, acetone and benzene, and is hardly soluble in petroleum ether. The extract is naturally present in stem and leaf of Artemisia scoparia of Compositae, and root of Artemisia capillaris, and Heteropappus japonicus of Asclepiadaceae, and can be used for preparing choleretic and other organic synthetic materials; animal experiments show that the product can increase the secretion of rat bile, and simultaneously increase the discharge amount of solid, cholic acid and bilirubin in the bile, and has the same effect on liver injury caused by carbon tetrachloride; the product is clinically used for treating hepatitis and has certain curative effect on jaundice abatement, so that the product is harmful to swallowing and has stimulation effect on eyes, respiratory system and skin.
Tocopherol acetate:
tocopherol acetate is a chemical substance, easily soluble in chloroform, diethyl ether, acetone and vegetable oil, soluble in alcohol, and insoluble in water. Has good heat resistance, can be oxidized when being exposed to light, and has dark color.
In one embodiment, the weight ratio of the thickener, the functional auxiliary agent, jojoba seed oil, the tocopherol acetate, the stearyl alcohol glycyrrhetinate and the sodium surfactin in the phase a component is (1.0-28): (0.2-13): (0.1-6.0): (0.01-1.0): (0.01-0.6): (0.01 to 1.0); preferably, the weight ratio of the thickening agent, the functional auxiliary agent, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium in the phase A component is (5-20): (3-10): (2.0-4.0): (0.1-0.8): (0.2-0.4): (0.1 to 0.8); more preferably, the weight ratio of the thickener, the functional aid, jojoba oil, the tocopherol acetate, the stearyl glycyrrhetinate and the sodium surfactin in the phase a component is 12.5: 6.5: 3.0: 0.3: 3.0: 0.45.
in one embodiment, the phase a component further comprises dimethicone and caprylic/capric triglyceride.
In one embodiment, the weight ratio of the simethicone, the caprylic/capric triglyceride and the jojoba seed oil is (0.1-5.0): (0.1-8.0): (0.1 to 6.0); preferably, the weight ratio of the dimethyl silicone oil, the caprylic/capric triglyceride and the jojoba seed oil is (1.0-4.0): (1.0-6.0): (1.0-5.0); more preferably, the weight ratio of dimethicone, caprylic/capric triglyceride and jojoba seed oil is 2.5: 3.5: 3.0.
the thickening agent of the specific components is added into the cream composition, so that cream in a paste shape can be promoted, the spreading, moisturizing, spot lightening, acne removing and whitening performances of the cream can be improved, the thickening agent is added according to the grouping conditions, the compatibility of each component is the largest, the surface tension is reduced as the largest as possible, the layering and coagulation phenomena of micro-phases cannot be generated, the mutual solubility of an oil phase and a water phase can be optimally promoted on a macro scale, the oil phase and the water phase are balanced, the viscosity is not too high, the spreading is not easy, the flowing state is avoided, the smearing and the absorption of facial skin are not easy, and the stability is better under different environments.
In one embodiment, the weight ratio of the alcohol substance, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate in the B phase component is (0.3-30): (0.1-1.0): (0.1-4.0): (0.1-10): (0.1-6.0): (0.1 to 7.0); preferably, the weight ratio of the alcohol substance, the allantoin, the tranexamic acid, the nicotinamide, the trisodium ascorbyl palmitate phosphate and the potassium citrate is (5-20): (0.3-0.8): (1.0-3.0): (2-8): (1.0-5.0): (1.0-6.0); more preferably, the weight ratio of the alcohol substance, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate is 12.5: 0.5: 2.0: 5.0: 3.0: 3.5.
in one embodiment, the alcohols in phase B component include glycerol, 1, 3-butanediol, and 1, 2-hexanediol; preferably, the weight ratio of the glycerol to the 1, 3-butanediol to the 1, 2-hexanediol is (0.1-10): (0.1-8.0): (0.1 to 10); more preferably, the weight ratio of glycerol, 1, 3-butanediol and 1, 2-hexanediol is 5.5: 3.5: 5.0.
nicotinamide:
the most important effect of niacinamide on skin anti-aging is to reduce and prevent dullness, yellowing, and sallowness of skin color during early aging. Of course, niacinamide contributes far more than this to the skin and can also repair the damaged stratum corneum lipid barrier, increasing skin resistance. The skin care product containing the niacinamide has strong water locking and moisturizing effects; topical niacinamide reduces the production of fatty acids and triglycerides in sebum, thereby narrowing pores and reducing the severity of acne when it occurs.
However, in general, nicotinamide is most stable in a solution with a pH of 6; in solutions with a pH above or below 6, it will hydrolyze to form niacin, which can cause skin irritation. Therefore, nicotinamide-containing formulations are typically controlled to a pH of between 5 and 7 to reduce niacin formation.
Panthenol:
panthenol is also called panthenol, is a transparent, slightly red and moisture-absorbing liquid and has a little special smell; is easily soluble in water, and is soluble in chloroform and diethyl ether; panthenol can be converted into pantothenic acid in skin and hair, and has effects of keeping moisture, relieving inflammation, and stimulating cell division.
Allantoin:
allantoin, also known as 5-ureylethanolamide, ureidoacetolactam, ureidohydantoin and uretidione, is a hydantoin derivative; at present, the annual production capacity of allantoin in the world is about 5 million tons, the market demand is mainly three fields of medicine, cosmetics and agriculture, and the traditional process for extracting natural allantoin from natural animals and plants is low in content, complex in process and high in cost, so that the allantoin cannot be applied in a large scale.
The pure allantoin is a non-toxic, tasteless, non-irritant and non-allergenic white crystal, and is crystallized in water into a prism or colorless crystalline powder; can be dissolved in hot water, hot alcohol and dilute sodium hydroxide solution; water and alcohol which are slightly soluble at normal temperature are difficult to dissolve in organic solvents such as ether and chloroform; the saturated aqueous solution (concentration is 0.6%) is slightly acidic; the pH is 5.5; is stable in aqueous solution with pH value of 4-9, and also stable in non-aqueous solvent and dry air; can be decomposed by boiling in strong alkaline solution and exposing in sunlight.
In the medical aspect: allantoin has physiological functions of promoting cell growth, accelerating wound healing, softening keratin and the like, and is a good healing agent and an anti-ulcer agent for skin wounds; can be used for relieving and treating xeroderma, scaling skin diseases, skin ulcer, digestive tract ulcer and inflammation, and has good therapeutic effect on osteomyelitis, diabetes, liver cirrhosis, and acne.
In the aspect of cosmetics: the allantoin is an amphoteric compound, can be combined with various substances to form a double salt, has the effects of shading light, sterilizing, preventing corrosion, relieving pain and resisting oxidation, can keep the skin moisture, moisten and soften, is a special additive of cosmetics such as beauty and hairdressing, and is widely used as an additive of freckle cream, acne liquid, shampoo, perfumed soap, toothpaste, shaving lotion, hair conditioner, astringent, anti-sweat deodorant lotion and the like; the cosmetic containing allantoin has tissue protecting, hydrophilic, water absorbing, and moisture diffusion preventing effects; hair cream, hair cream and shampoo containing allantoin can protect hair and prevent hair from bifurcation and break hair; the lipstick and the face cream added with the allantoin can make the skin and the lips soft and elastic and have beautiful luster; allantoin promotes tissue growth, cell metabolism, and softens stratum corneum protein.
In agriculture: allantoin is an excellent plant growth regulator, can stimulate plant growth, has obvious yield increasing effect on wheat, orange, rice, vegetable, soybean and the like, and has the functions of fruit fixing and early maturing.
Experiments show that when the niacinamide is added into a composition system, the anti-aging property and the moisture retention property of the cream can be effectively improved, and the phenomena of obturator, acne and speckle fading can be reduced, but the skin can sometimes generate an allergic phenomenon, which is probably because the niacinamide is hydrolyzed in vivo to form nicotinic acid, the content of the nicotinic acid is higher, the vasodilatation is promoted, the water flow is promoted, and the erythra is generated; the phenomenon can be weakened when allantoin is added into the composition, and probably because the allantoin can fix formed nicotinic acid, the flowing and the action of the nicotinic acid in the skin are reduced, the moisture retention performance of the system is improved, the diffusion of water is reduced, the absorption of the components by the skin is promoted, and the generation of erythema is reduced.
Potassium citrate:
potassium citrate (Potassium citrate), also known as Potassium citrate, tripotassium citrate; the potassium citrate is a citrate with a molecular formula of C6H5K3O7Molecular weight 306.39500, which is a white crystalline powder slightly hygroscopic, odorless, tasteless, readily soluble in water, slowly soluble in glycerol, insoluble in alcohol, salty and cool in taste, used as a stabilizer, pH buffer, etc. The food can be used for various foods according to the national regulations, and is used in a proper amount according to the production requirements; in medical treatment, it can be used for controlling uric acid or cystine from kidney stone, and preventing and treating hypokalemia and alkalized urine.
In one embodiment, the weight ratio of polyacrylate-13, polyisobutylene, and polysorbate-20 in the phase C component is 1: (0.8-2.0): (0.5 to 1.5); preferably, the weight ratio of the polyacrylate-13, the polyisobutylene and the polysorbate-20 is 1: 1.5: 1.
in one embodiment, the weight ratio of panthenol to xylitol in the phase D component is (0.1-3.0): (0.01-4.0); preferably, the weight ratio of the panthenol to the xylitol substances is (1.0-2.0): (1.0-4.0); more preferably, the weight ratio of panthenol to xylitol is 1.5: 2.5.
in one embodiment, the xylitol-like substances in phase D component include xylitol-based glucosides, anhydroxylitol, and xylitol; preferably, the weight ratio of xylitol-based glucoside to anhydroxylitol to xylitol is 1: (1-3): (1-3); more preferably, the weight ratio of xylitol-based glucoside to anhydroxylitol to xylitol is 1: 2: 2.
firstly, it is unexpectedly found that the anti-aging and whitening performances of a cream system can be effectively improved by adding a certain amount of tranexamic acid, nicotinamide, potassium citrate and trisodium ascorbyl palmitate phosphate into a composition system, and probably because the nicotinamide can effectively avoid the oxidation problem after the trisodium ascorbyl palmitate phosphate is hydrolyzed to form ascorbic acid while maintaining the pH stability of the system, the action time and the action efficiency of the cream are prolonged; meanwhile, the problem of skin allergy caused by hydrochloric acid formed by hydrolysis of nicotinamide is also avoided;
the potassium citrate can adjust the pH of the system and maintain the pH of the system to be 7.5-7.8, and the formed alkalescent system is strong in surface activity, good in permeability and strong in dissolving power, so that the alkalescent system is easy to participate in a series of biochemical activities of cells, alkalescent water can neutralize acidic products of cell metabolism to a certain extent, and the whitening effect of the cream is improved; but also easily dry the skin, and can dry, tighten and even itch the skin; however, the applicant has found that the composition system provided by the present invention does not have such problems, and may form a dense network structure on the skin surface under the synergistic effect of the thickener, the phase C and the phase D components, so as to have good moisture retention property, and simultaneously form a hydrophobic layer on the skin surface to reduce moisture diffusion.
The second aspect of the invention provides a preparation method of the composition of the whitening and spot-lightening cream, which comprises the following steps:
(1) adding the substances in the component A into an oil phase pot, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component in the step 2, and uniformly mixing;
(4) cooling, adding the C phase component, and uniformly stirring;
(5) cooling, adding the phase D component, and stirring to obtain the cream composition.
Preferably, the preparation method of the composition of the whitening and spot-lightening cream comprises the following steps:
(1) adding the substances in the component A into an oil phase pot at the temperature of 80-85 ℃ and the pressure of-0.5-1 MPa, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot at the temperature of 80-85 ℃ and the pressure of-0.5-1 MPa, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component obtained in the step 2, and uniformly mixing the phase A component and the phase B component at the temperature of 80-85 ℃ and the pressure of-0.5-1 MPa;
(4) cooling to 70-75 ℃, adding the C-phase component, and stirring uniformly under the condition of-0.5-1 MPa;
(5) and cooling to 40-45 ℃, adding the phase D component, and uniformly stirring under the condition of-0.5-1 MPa to obtain the cream composition.
More preferably, the preparation method of the composition of the whitening and spot-lightening cream comprises the following steps:
(1) adding the substances in the component A into an oil phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component obtained in the step 2, and uniformly mixing the phase A component and the phase B component at the temperature of 80-85 ℃ and the pressure of-0.65 MPa;
(4) cooling to 70-75 ℃, adding the C phase component, and uniformly stirring under the condition of-0.65 MPa;
(5) and cooling to 40-45 ℃, adding the phase D component, and uniformly stirring under the condition of-0.65 MPa to obtain the cream composition.
The third aspect of the invention provides a whitening and spot-lightening cream, and a composition containing the whitening and spot-lightening cream.
Example 1
Example 1 of the present invention provides a composition for whitening spot-lightening cream, which comprises 30% of phase a component, 35% of phase B component, 3.5% of phase C component, 4.5% of phase D component and the balance of water by weight;
the phase A component comprises a thickening agent, a functional additive, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate, sodium surfactin, simethicone and caprylic/capric triglyceride;
the weight ratio of the thickening agent, the functional auxiliary agent, jojoba seed oil, tocopherol acetate, stearyl alcohol glycyrrhetinate and surfactin sodium in the phase A component is 12.5: 6.5: 3.0: 0.3: 3.0: 0.45 of; the weight ratio of the simethicone, the caprylic/capric triglyceride and the jojoba seed oil is 2.5: 3.5: 3.0;
the thickening agent comprises a first component, a second component, a third component and a fourth component; wherein the first component comprises arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside, the second component comprises oleyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol and cetyl alcohol, the third component comprises glyceryl stearate and PEG-100 stearate, and the fourth component comprises cetyl alcohol and cetyl ethyl hexanoate;
the weight ratio of the first component to the second component to the third component to the fourth component is 1.5: 2.5: 2.0: 13;
the weight ratio of arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside in the first component is 1: 2.2: 1.8;
the weight ratio of the stearyl alcohol, the behenyl alcohol, the palmitic acid, the stearic acid, the lecithin, the lauryl alcohol, the myristyl alcohol and the cetyl alcohol in the second component is 1: 1.3: 1.5: 1.5: 2.0: 2.0: 2.1: 1.6;
the weight ratio of glyceryl stearate to PEG-100 stearate in the third component is 1: 1.25;
the weight ratio of the cetyl stearate alcohol to the cetyl ethylhexanoate in the fourth component is 1: 5;
the functional auxiliary agent comprises pepper seed extract, p-hydroxyacetophenone, hydrogenated polyisobutene and dodecanoylphenylalanine, wherein the weight ratio of the pepper seed extract to the p-hydroxyacetophenone to the hydrogenated polyisobutene to the dodecanoylphenylalanine is 0.25: 0.45: 5.5: 0.45 of;
the phase B component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate, wherein the weight ratio of the alcohol substances to the allantoin to the tranexamic acid to the nicotinamide to the trisodium ascorbyl palmitate phosphate to the potassium citrate is 12.5: 0.5: 2.0: 5.0: 3.0: 3.5;
the alcohol substances in the phase B component comprise glycerol, 1, 3-butanediol and 1, 2-hexanediol, wherein the weight ratio of the glycerol to the 1, 3-butanediol to the 1, 2-hexanediol is 5.5: 3.5: 5.0;
the phase C component comprises polyacrylate-13, polyisobutylene and polysorbate-20, wherein the weight ratio of the polyacrylate-13 to the polyisobutylene to the polysorbate-20 is 1: 1.5: 1;
the phase D component comprises panthenol and xylitol substances, wherein the weight ratio of the panthenol to the xylitol substances is 1.5: 2.5;
the xylitol substances in the phase D component comprise xylitol-based glucoside, dehydrated xylitol and xylitol, wherein the weight ratio of the xylitol-based glucoside to the dehydrated xylitol to the xylitol is 1: 2: 2;
the preparation method of the composition of the whitening spot-lightening cream comprises the following steps:
(1) adding the substances in the component A into an oil phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component obtained in the step 2, and uniformly mixing the phase A component and the phase B component at the temperature of 80-85 ℃ and the pressure of-0.65 MPa;
(4) cooling to 70-75 ℃, adding the C phase component, and uniformly stirring under the condition of-0.65 MPa;
(5) and cooling to 40-45 ℃, adding the phase D component, and uniformly stirring under the condition of-0.65 MPa to obtain the cream composition.
Example 2
Example 2 of the present invention provides a composition for whitening spot-lightening cream, which comprises 15% of phase a component, 20% of phase B component, 2.0% of phase C component, 2.0% of phase D component and the balance of water by weight;
the phase A component comprises a thickening agent, a functional additive, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate, sodium surfactin, simethicone and caprylic/capric triglyceride;
the weight ratio of the thickening agent, the functional auxiliary agent, jojoba seed oil, tocopherol acetate, stearyl alcohol glycyrrhetinate and surfactin sodium in the phase A component is 1.0: 0.2: 0.1: 0.01: 0.01: 0.01; the weight ratio of the dimethyl silicone oil, the caprylic/capric triglyceride and the jojoba seed oil is 1: 1: 1;
the thickening agent comprises a first component, a second component, a third component and a fourth component; wherein the first component comprises arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside, the second component comprises oleyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol and cetyl alcohol, the third component comprises glyceryl stearate and PEG-100 stearate, and the fourth component comprises cetyl alcohol and cetyl ethyl hexanoate;
the weight ratio of the first component to the second component to the third component to the fourth component is 0.5: 0.2: 0.1: 0.2;
the weight ratio of arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside in the first component is 1: 0.5: 1;
the weight ratio of the stearyl alcohol, the behenyl alcohol, the palmitic acid, the stearic acid, the lecithin, the lauryl alcohol, the myristyl alcohol and the cetyl alcohol in the second component is 1: 0.5: 0.5: 0.5: 1: 1: 1: 0.8;
the weight ratio of glyceryl stearate to PEG-100 stearate in the third component is 1: 0.8;
the weight ratio of the cetyl stearate alcohol to the cetyl ethylhexanoate in the fourth component is 1: 1;
the functional auxiliary agent comprises pepper seed extract, p-hydroxyacetophenone, hydrogenated polyisobutene and dodecanoylphenylalanine, wherein the weight ratio of the pepper seed extract to the p-hydroxyacetophenone to the hydrogenated polyisobutene to the dodecanoylphenylalanine is 0.25: 0.45: 5.5: 0.45 of;
the phase B component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate, wherein the weight ratio of the alcohol substances to the allantoin to the tranexamic acid to the nicotinamide to the trisodium ascorbyl palmitate phosphate to the potassium citrate is 0.3: 0.1: 0.1: 0.1: 0.1: 0.1;
the alcohol substances in the phase B component comprise glycerol, 1, 3-butanediol and 1, 2-hexanediol, wherein the weight ratio of the glycerol to the 1, 3-butanediol to the 1, 2-hexanediol is 1: 1: 1;
the phase C component comprises polyacrylate-13, polyisobutylene and polysorbate-20, wherein the weight ratio of the polyacrylate-13 to the polyisobutylene to the polysorbate-20 is 1: 0.8: 0.5;
the phase D component comprises panthenol and xylitol substances, wherein the weight ratio of the panthenol to the xylitol substances is 0.1: 0.01;
the xylitol substances in the phase D component comprise xylitol-based glucoside, dehydrated xylitol and xylitol, wherein the weight ratio of the xylitol-based glucoside to the dehydrated xylitol to the xylitol is 1: 1: 1;
the preparation method of the composition of the whitening spot-lightening cream comprises the following steps:
(1) adding the substances in the component A into an oil phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component obtained in the step 2, and uniformly mixing the phase A component and the phase B component at the temperature of 80-85 ℃ and the pressure of-0.65 MPa;
(4) cooling to 70-75 ℃, adding the C phase component, and uniformly stirring under the condition of-0.65 MPa;
(5) and cooling to 40-45 ℃, adding the phase D component, and uniformly stirring under the condition of-0.65 MPa to obtain the cream composition.
Example 3
Example 3 of the present invention provides a composition for whitening spot-lightening cream, which comprises 40% of phase a component, 43% of phase B component, 7.0% of phase C component, 8.0% of phase D component and the balance of water by weight;
the phase A component comprises a thickening agent, a functional additive, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate, sodium surfactin, simethicone and caprylic/capric triglyceride;
the weight ratio of the thickening agent, the functional auxiliary agent, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium in the phase A component is 28: 13: 6.0: 1.0: 0.6: 1.0; the weight ratio of the simethicone, the caprylic/capric triglyceride and the jojoba seed oil is 5.0: 8.0: 6.0;
the thickening agent comprises a first component, a second component, a third component and a fourth component; wherein the first component comprises arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside, the second component comprises oleyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol and cetyl alcohol, the third component comprises glyceryl stearate and PEG-100 stearate, and the fourth component comprises cetyl alcohol and cetyl ethyl hexanoate;
the weight ratio of the first component to the second component to the third component to the fourth component is 3.0: 5.0: 3.0: 17;
the weight ratio of arachidyl alcohol, behenyl alcohol and arachidyl alcohol glucoside in the first component is 1: 3: 3;
the weight ratio of the stearyl alcohol, the behenyl alcohol, the palmitic acid, the stearic acid, the lecithin, the lauryl alcohol, the myristyl alcohol and the cetyl alcohol in the second component is 1: 2: 2: 2: 3: 3: 3: 2.5;
the weight ratio of glyceryl stearate to PEG-100 stearate in the third component is 1: 2.5;
the weight ratio of the cetyl stearate alcohol to the cetyl ethylhexanoate in the fourth component is 1: 10;
the functional auxiliary agent comprises pepper seed extract, p-hydroxyacetophenone, hydrogenated polyisobutene and dodecanoylphenylalanine, wherein the weight ratio of the pepper seed extract to the p-hydroxyacetophenone to the hydrogenated polyisobutene to the dodecanoylphenylalanine is 0.25: 0.45: 5.5: 0.45 of;
the phase B component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, trisodium ascorbyl palmitate phosphate and potassium citrate, wherein the weight ratio of the alcohol substances to the allantoin to the tranexamic acid to the nicotinamide to the trisodium ascorbyl palmitate phosphate to the potassium citrate is 30: 1.0: 4.0: 10: 6.0: 7.0;
the alcohol substances in the phase B component comprise glycerol, 1, 3-butanediol and 1, 2-hexanediol, wherein the weight ratio of the glycerol to the 1, 3-butanediol to the 1, 2-hexanediol is 10: 8: 10;
the phase C component comprises polyacrylate-13, polyisobutylene and polysorbate-20, wherein the weight ratio of the polyacrylate-13 to the polyisobutylene to the polysorbate-20 is 1: 2.0: 1.5;
the phase D component comprises panthenol and xylitol substances, wherein the weight ratio of the panthenol to the xylitol substances is 3.0: 4.0;
the xylitol substances in the phase D component comprise xylitol-based glucoside, dehydrated xylitol and xylitol, wherein the weight ratio of the xylitol-based glucoside to the dehydrated xylitol to the xylitol is 1: 3: 3;
the preparation method of the composition of the whitening spot-lightening cream comprises the following steps:
(1) adding the substances in the component A into an oil phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(2) adding the substances in the component B into a water phase pot at the temperature of 80-85 ℃ and the pressure of-0.65 MPa, and uniformly stirring;
(3) pouring the uniformly mixed phase A component into the phase B component obtained in the step 2, and uniformly mixing the phase A component and the phase B component at the temperature of 80-85 ℃ and the pressure of-0.65 MPa;
(4) cooling to 70-75 ℃, adding the C phase component, and uniformly stirring under the condition of-0.65 MPa;
(5) and cooling to 40-45 ℃, adding the phase D component, and uniformly stirring under the condition of-0.65 MPa to obtain the cream composition.
Example 4
Example 4 of the present invention provides a composition for whitening spot-lightening cream, which is the same as example 1 except that the content of dimethicone and caprylic/capric triglyceride in the phase a component is 0.
Example 5
Example 5 of the present invention provides a composition for whitening spot-lightening cream, which is similar to example 1 except that the content of niacinamide in the phase B component is 0.
Example 6
Example 6 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the content of allantoin in the phase B component is 0.
Example 7
Example 7 of the present invention provides a composition for whitening spot-lightening cream, which is similar to example 1 except that the content of allantoin and nicotinamide in the phase B component is 0.
Example 8
Example 8 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the content of tranexamic acid in the phase B component is 0.
Example 9
Example 9 of the present invention provides a composition for whitening spot-lightening cream, which is similar to example 1 except that the content of potassium citrate in the phase B component is 0.
Example 10
Example 10 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the first component of the thickener contained in the phase a component is 0.
Example 11
Example 11 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the second component of the thickener contained in the phase a component is 0.
Example 12
Example 12 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the content of the third component of the thickener in the phase a component is 0.
Example 13
Example 13 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the content of the fourth component of the thickener in the phase a component is 0.
Example 14
Example 14 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the first component and the second component of the thickener contained in the phase a component are each 0.
Example 15
Example 15 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the first, second and third components of the thickener contained in the phase a component are each 0.
Example 16
Example 16 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1, except that the content of the second, third and fourth components of the thickener in the phase a component is 0.
Example 17
Example 17 of the present invention provides a composition for whitening spot-lightening cream, which is the same as example 1 in specific embodiment, except that the thickener in the phase a component includes a first component, a second component, a third component, and a fourth component;
the first component comprises arachidyl alcohol, behenyl alcohol and lauryl alcohol, the second component comprises oleyl alcohol, behenyl alcohol, stearic acid, cetyl ethyl hexanoate, arachidyl glucoside, myristyl alcohol and cetyl alcohol, the third component comprises glyceryl stearate and PEG-100 stearate, and the fourth component comprises cetyl stearate, palmitic acid and lecithin.
Example 18
Example 18 of the present invention provides a composition for whitening spot-lightening cream, which is the same as example 1 except that the weight ratio of the first component, the second component, the third component and the fourth component of the thickener in the phase a component is 5: 5: 3: 19.
example 19
Example 19 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as example 1 except that the content of the phase C component is 0.
Example 20
Example 20 of the present invention provides a composition for whitening spot-lightening cream, which is substantially the same as in example 1, except that the content of the phase D component is 0.
Performance evaluation:
1. appearance of cream composition: placing the cream composition prepared in the examples 1-20 at room temperature, observing the appearance of the cream composition, referring to the standard part table 1, and showing the experimental results in the table 2;
2. heat resistance: carrying out heat-resistant and cold-resistant detection tests according to the quality detection standard of cream cosmetics of the national light industry standard, wherein the detection method is respectively that the heat-resistant test is to place the cream composition prepared in the embodiment 1-20 in a constant temperature box at 45 ℃ for 24h, observe the appearance and the oil-water separation phenomenon, the reference standard is shown in table 1, and the experimental result is shown in table 2;
3. skin effect test: in order to reflect the using effect more accurately, the experiment invites 20 groups, 50 professional testers with facial speckle fading in different age groups (10 people in 20, 30, 40, 50 and 60 years old) in each group evaluate the comprehensive characteristics of the senses, including spreadability, fineness and whitening effect, and the average value is taken as the final score; specific scoring criteria are shown in table 1; in addition, whether or not the rash appeared was observed, and the proportion of the rash appeared was calculated, and the experimental results are shown in Table 2.
TABLE 1 evaluation criteria for Performance
Table 2 results of performance testing
The experimental results show that the whitening and spot-lightening agent can effectively improve the whitening effect of skin and eliminate the spot-lightening of the face; in addition, the composition has good appearance, proper viscosity, easy spreading and good fineness, does not present a flowing emulsion state, is easy to smear and absorb by facial skin, does not cause phenomena of allergy and the like, and enlarges the application range of the product; on the other hand, the composition provided by the invention has good stability and is easy to store.
It should be noted that the above mentioned embodiments are only preferred embodiments of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention.
Claims (3)
1. The composition for whitening and spot-fading face cream is characterized by comprising 15-35% of phase A component, 20-40% of phase B component, 2.0-5.0% of phase C component, 2.0-6.0% of phase D component and the balance of water in percentage by weight;
wherein the content of the first and second substances,
the phase A component comprises a thickening agent, a functional auxiliary agent, jojoba seed oil, tocopherol acetate, stearyl glycyrrhetinate and surfactin sodium in a weight ratio of (1.0-28): (0.2-13): (0.1-6.0): (0.01-1.0): (0.01-0.6): (0.01-1.0);
the phase B component comprises alcohol substances, allantoin, tranexamic acid, nicotinamide, ascorbyl palmitate phosphate trisodium and potassium citrate in a weight ratio of (0.3-30): (0.1-1.0): (0.1-4.0): (0.1-10): (0.1-6.0): (0.1-7.0);
the phase C component is prepared from polyacrylate-13, polyisobutylene and polysorbate-20 in a weight ratio of 1: (0.8-2.0): (0.5-1.5);
the phase D component comprises panthenol and xylitol substances in a weight ratio of (0.1-3.0): (0.01-4.0); the thickening agent comprises a first component, a second component, a third component and a fourth component;
wherein the first component is prepared from arachidyl alcohol, behenyl alcohol and arachidyl glucoside in a weight ratio of 1: (0.5-3): (1-3);
the second component is prepared from stearyl alcohol, behenyl alcohol, palmitic acid, stearic acid, lecithin, lauryl alcohol, myristyl alcohol and cetyl alcohol in a weight ratio of 1: (0.5-2): (0.5-2): (0.5-2): (1-3): (1-3): (1-3): (0.8-2.5);
the third component is prepared from glycerol stearate and PEG-100 stearate in a weight ratio of 1: (0.8-2.5);
the fourth component is prepared from cetearyl alcohol and cetyl ethyl hexanoate in a weight ratio (0.1-7.0): (0.1-10.0);
the weight ratio of the first component to the second component to the third component to the fourth component is (0.5-3.0): (0.2-5.0): (0.1-3.0): (0.2 to 17.0);
the xylitol substances are prepared from xylitol-based glucoside, dehydrated xylitol and xylitol according to a weight ratio of 1: (1-3): (1-3);
the functional adjuvant comprises pepper seed extract, p-hydroxyacetophenone, hydrogenated polyisobutene and dodecanoylphenylalanine.
2. A method for preparing the composition of the whitening spot-lightening cream according to claim 1, which is characterized by comprising the following steps: (1) adding the substances in the component A into an oil phase pot, and uniformly stirring; (2) adding the substances in the component B into a water phase pot, and uniformly stirring; (3) pouring the uniformly mixed phase A component into the phase B component in the step 2, and uniformly mixing; (4) cooling, adding the C phase component, and uniformly stirring; (5) cooling, adding the phase D component, and stirring to obtain the cream composition.
3. A whitening spot-lightening cream characterized by comprising the composition of the whitening spot-lightening cream according to claim 1.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101590003A (en) * | 2009-06-23 | 2009-12-02 | 广州保税区雅兰国际化妆品有限公司 | A kind of whitening spot-relieving cream cosmetic and preparation method thereof |
| CN105616312A (en) * | 2014-10-31 | 2016-06-01 | 沈阳市坤美惜美容用品有限公司 | Spot-removal cosmetic and preparation method thereof |
| KR20170009107A (en) * | 2015-07-15 | 2017-01-25 | 미 정 박 | cosmetic method of manufacture method |
| JP2017101018A (en) * | 2015-11-06 | 2017-06-08 | ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド | Topical gel cream composition |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101590003A (en) * | 2009-06-23 | 2009-12-02 | 广州保税区雅兰国际化妆品有限公司 | A kind of whitening spot-relieving cream cosmetic and preparation method thereof |
| CN105616312A (en) * | 2014-10-31 | 2016-06-01 | 沈阳市坤美惜美容用品有限公司 | Spot-removal cosmetic and preparation method thereof |
| KR20170009107A (en) * | 2015-07-15 | 2017-01-25 | 미 정 박 | cosmetic method of manufacture method |
| JP2017101018A (en) * | 2015-11-06 | 2017-06-08 | ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド | Topical gel cream composition |
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