CN115919733A - Cosmetic composition for removing acne and preparation method thereof - Google Patents

Abstract

The invention provides a cosmetic composition for removing acne and a preparation method thereof, and relates to the technical field of cosmetics. The cosmetic composition comprises, by mass, 0.01-2.0% of Caesalpinia spinosa gum, 0.01-2.0% of sphingosine monad fermentation product extract, 0.01-10% of stripping agent, 0.01-1.0% of oil control agent, 0.001-0.005% of bacteriostatic agent, 0.01-2.0% of anti-inflammatory agent and 0.01-2.0% of soothing and repairing agent; the balance of cosmetic matrix; wherein the exfoliating agent comprises one or more of encapsulated multi-fruit acid, encapsulated azelaic acid, and encapsulated salicylic acid; the anti-inflammatory agent comprises

100 and

1609; and, soothing and repairing agents comprising

100, the technical problems that the acne-removing product is difficult to thicken, not mild enough and not refreshing after being absorbed are solved.

Description

Cosmetic composition for removing acne and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a cosmetic composition for removing acne and a preparation method thereof.

Background

Common acne is also called comedo, is a skin disease caused by chronic inflammation of sebaceous glands, and is developed and generated due to noninflammatory hair follicle reaction caused by very tight hair follicles and excessive angles. The incidence of acne is concentrated in people of 11-25 years old, the affected parts are mainly on the face, the chest and the back, and a small amount of the affected parts exist on four limbs, severe acne is easy to develop into pustules and cysts, the appearance and the mental state of skin are seriously affected, partial people can accumulate pustules by hands, and scars, namely pockmarks, are easy to leave after the pustules are broken. Acne patients are easy to be depressed and inferior psychology, which brings great harm to the mind and body of the patients.

Acne grading is an important basis for acne treatment and efficacy evaluation, and dermatology generally divides acne into 3 degrees and 4 grades: mild (grade i): acne alone; medium (grade II): inflammatory papules; medium (grade iii): pustules; severe (iv): cysts and nodules.

The causes of acne are: 1. androgen regulates the sebaceous gland abnormally and the sebaceous gland is hyperfunction; 2. abnormal sebaceous gland duct keratinization, i.e. excessive hair follicle keratinization; 3. excessive propagation of propionibacterium acnes; 4. inflammatory immune response. Other factors that may cause acne are: diet, skin cleaning, daily life and work environment, illumination environment, cosmetic effects, etc.

In the method for preparing the acne-removing cosmetic in the prior art, salicylic acid or derivatives thereof are often used as the added exfoliating agent. For example, CN113893209A discloses an acne-removing and repairing functional composition, which comprises salicylic acid, centella asiatica extract, salix alba extract, 4-terpineol, chlorella vulgaris extract, ergothioneine, matsutake mushroom extract, burdocarpus spicata leaf extract and 10-hydroxydecanoic acid. Salicylic acid is a fat-soluble compound and has certain irritation to the skin. The salicylic acid is wrapped by the microcapsules or prepared into salicylic acid derivatives, so that the water solubility of the salicylic acid derivatives can be improved, the slow release performance of the salicylic acid derivatives can be improved, and the irritation of the salicylic acid derivatives can be reduced. For example, CN111228153A discloses a composition with synergistic acne removing effect, which comprises PCA zinc, encapsulated salicylic acid, quaternary ammonium salt-73, niacinamide and tea tree essential oil.

Salicylic acid water has poor solubility, and after alkaline substances such as potassium hydroxide are added to neutralize the salicylic acid water to form salt, the solubility is improved, but the acne removing effect is reduced, so that the pH of many salicylic acid products is still relatively low, the irritation is high, and the salicylic acid products can only be applied by a spot. Salicylates, encapsulated salicylic acid, and cosmetics using zinc PCA as the oil control agent are difficult to thicken because the thickeners commonly used in cosmetics are not ion resistant. In conclusion, the commercial products for removing acne have the following disadvantages: not mild enough, the product is too sticky and not refreshing after absorption. Therefore, how to improve the defects of the acne-removing products is a problem to be solved at present.

In view of the above, the present invention is particularly proposed.

Disclosure of Invention

The invention aims to provide a cosmetic composition for removing acnes and a preparation method thereof, so as to relieve at least one of the defects of removing acnes on the market in the prior art.

In order to solve the technical problems, the invention adopts the following technical scheme:

according to one aspect of the invention, the invention provides a cosmetic composition for removing acne, which comprises, by mass, 0.01-2.0% of Caesalpinia spinosa Gum, 0.01-2.0% of sphingomonas sp fermentation product extract, 0.01-10% of exfoliating agent, 0.01-1.0% of oil control agent, 0.001-0.005% of bacteriostatic agent, 0.01-2.0% of anti-inflammatory agent and 0.01-2.0% of soothing and repairing agent; the balance of cosmetic base material;

the exfoliating agent comprises one or more of encapsulated polyfructonic acid, encapsulated azelaic acid and encapsulated salicylic acid, the encapsulated azelaic acid comprising PG6 ACTIVE AA-GLY C; the encapsulated multi-fruit acid comprises SKINPERF LWG;

the anti-inflammatory agent comprises

100 and->

1609；

The soothing and repairing agent comprises

100。

Preferably, the exfoliating agent comprises PG6 ACTIVE AA-GLY C and SKINPERF LWG;

preferably, the oil control agent comprises one or more of zinc PCA, plankton extract and lotus japonicus extract, preferably zinc PCA;

preferably, the bacteriostatic agent comprises one or more of quaternary ammonium salt-73, caprylyl glycine and white willow bark extract, preferably quaternary ammonium salt-73;

preferably, the anti-inflammatory agent further comprises one or more of panthenol, dipotassium glycyrrhizinate, and licorice derivatives;

preferably, the soothing conditioner further comprises one or more of madecassoside, centella asiatica extract and ceramide;

preferably, the cosmetic composition for removing acne has a pH of 4.5 to 6.0, preferably 4.5 to 5.5.

Preferably, the cosmetic composition comprises Caesalpinia Spinosa, sphingomonas sp.fermentation product extract, PG6 ACTIVE AA-GLY C, SKINPERF LWG, zinc PCA, quaternary ammonium-7, and,

100、/>

1609 and +>

100；

Preferably, the cosmetic composition comprises 0.3-0.5% of Caesalpinia spinosa gum, 0.15-0.25% of Sphingomonas sp fermentation product extract, 2% of PG6 ACTIVE AA-GLY C, 2% of SKINPERF LWG, 0.25% of zinc PCA, 0.002-0.003% of quaternary ammonium salt-73,

100 0.2％、/>

16091.0 to 2.0% and

1001 percent; the balance is cosmetic matrix.

Preferably, the cosmetic base comprises one or more of solvents, surfactants, solubilisers, thickeners, skin conditioning agents, oils, humectants, preservatives, chelating agents, pH adjusters and perfumes.

Preferably, the cosmetic composition is an aqueous, emulsion, cream or gel;

preferably, the cosmetic composition is a lotion, toner, essence lotion, emulsion, cream, essence cream, gel, spray, mask, skin base solution, application mask or patch mask.

Preferably, the composition comprises, by mass, 0.3-0.5% of Caesalpinia spinosa gum, 0.15-0.25% of sphingomonas ferment product extract, 2% of PG6 ACTIVE AA-GLY C, 2% of SKINPERF LWG, 0.25% of zinc PCA, 0.003% of quaternary ammonium salt,

100 0.2％、/>

16091.0% and->

100 1％；

Also contains cosmetic matrix, wherein the cosmetic matrix comprises 3% of glycerol, 0.02% of EDTA disodium, 0.5% of 1, 2-hexanediol, 0.5% of p-hydroxyacetophenone and 3% of 1, 3-propylene glycol; also comprises a pH regulator, a solubilizer and the balance of deionized water.

Preferably, the composition comprises, by mass, 0.3-0.45% of Caesalpinia spinosa gum, 0.15-0.22% of sphingomonas ferment product extract, 2% of PG6 ACTIVE AA-GLY C, 2% of SKINPERF LWG, 0.25% of PCA zinc, 0.002% of quaternary ammonium salt-73.002%,

100 0.2％、/>

16091.2% and->

100 1％；

Also contains a cosmetic matrix, wherein the cosmetic matrix comprises 3 percent of glycerol, 0.2 percent of sodium stearyl glutamate, 0.05 percent of EDTA disodium, 3 to 5 percent of stearyl alcohol, 1 percent of dimethicone kf-96A-6T,

Ultimate 5％、/>

165CN 1%, montanov L1%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5% and 1, 3-propanediol 3%;

also comprises a pH regulator, essence and the balance of deionized water.

According to another aspect of the present invention, there is also provided a process for preparing the above cosmetic composition, comprising mixing the ingredients in the amounts formulated;

preferably, the preparation method comprises: respectively dissolving the bacteriostatic agent and the oil control agent; dispersing the Spindaea spinosa and the sphingosine monad fermentation product extract in a solvent, mixing the dissolved or dispersed systems, adding the other components, and uniformly mixing to obtain the cosmetic composition;

preferably, the preparation method comprises:

dissolving quaternary ammonium salt-73 in polyhydric alcohol to obtain a first system; dissolving PCA zinc in part of deionized water according to the formula amount to obtain a second system; dispersing the fermentation product of the Caesalpinia spinosa and the sphingosine monad in the residual deionized water to obtain a third system;

uniformly mixing the first system, the second system, the third system and the rest components to obtain the cosmetic composition;

preferably, quaternary ammonium salt-73 is dissolved in polyol at 60-75 ℃ to obtain the first system;

preferably, quaternary ammonium salt-73 is dissolved in polyol at 65-75 ℃ to obtain the first system;

preferably, the second system is obtained by dissolving zinc PCA in a part of the formulated amount of deionized water at 50-60 ℃;

preferably, the Caesalpinia spinosa and the sphingosine monad fermentation product extract which are uniformly dispersed in the residual deionized water are heated to 82-88 ℃, are continuously homogenized for 5-10 min, are cooled to 50-55 ℃, and are mixed with other components.

Compared with the prior art, the invention has the following beneficial effects:

the cosmetic composition for removing acnes provided by the invention comprises caesalpinia spinosa gum, a sphingomonas fermentation product extract, an exfoliating agent, an oil control agent, a bacteriostatic agent, an anti-inflammatory agent and a soothing and repairing agent.

Wherein the exfoliating agent comprises one or more of encapsulated polyfructonic acid, encapsulated azelaic acid, and encapsulated salicylic acid. Acid is wrapped, so that the product has stripping performance and simultaneously has the advantage of mildness, a common stripping agent can take effect under the acidic condition, the stripping agent can take effect within the range of pH 5-5.5, the acidity of the whole cosmetic composition system is prevented from being too strong, and the product is milder compared with a commercially available stripping type acne removing product, and the defect that the acne removing product in the prior art is not mild enough is overcome.

The stripping agent and the thickening agent are improved, the wrapped acid is used as the stripping agent to avoid the pH value of the system from being too low, and meanwhile, the sphingomonas fermentation product extract and the tara gum are selected to be compounded and used as the thickening component, so that the stripping agent has the advantages of acid resistance and electrolyte resistance, the cosmetic composition can have better viscosity under the acidic condition, the skin feel is fresh, and the cosmetic composition has the feeling of being quickly absorbed in the application process.

The stripping type cosmetic composition has certain irritation, so that most of the traditional stripping type cosmetics are applied to the affected part in a spot mode and cannot be used on the whole face.

Also, soothing treatments include

100 which also have an antihistamine and anti-inflammatory action in combination with a substance containing: ->

100 and->

1609 the anti-inflammatory agent provides soothing, repairing, and anti-acne benefits to the cosmetic composition, which can be applied to the whole face without irritation.

The cosmetic composition disclosed by the invention has synergistic effects of resisting inflammation, inhibiting bacteria, controlling oil and stripping in an acne removing direction through the specific thickening component and the compound use of the stripping agent, the oil control agent, the bacteriostatic agent, the anti-inflammatory agent and the soothing and repairing agent, so that the obtained composition can play a role in quickly removing acnes. The cosmetic composition provided by the invention is different from the commercially available acne-removing products in a spot-coating mode, can be coated on the whole face, and is very mild. By adding the anti-inflammatory agent and the repairing agent, the cosmetic composition is mild and non-irritating, and has the effects of relieving, repairing and removing acnes. The composition can be used in cosmetic for removing acne, and can also be used in skin care product fields such as soothing, repairing, and moisturizing.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a chart of the acquisition of the red region in example 3, wherein A is the acquisition of the red region on day 0, B is the acquisition of the red region on day 14, and C is the acquisition of the red region on day 28;

fig. 2 is a photograph of stability test of examples and comparative examples, the left photograph is a photograph of stability test of examples, and the right photograph is a photograph of stability test of comparative example 7.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be apparent that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that:

in the present invention, all embodiments and preferred embodiments mentioned herein may be combined with each other to form a new technical solution, if not specifically stated; all the technical features mentioned herein, as well as preferred features, can be combined with each other to form new solutions; the components concerned or their preferred components can be combined with one another to form new solutions.

In the present invention, unless otherwise stated, the numerical range "a-b" represents a shorthand representation of any combination of real numbers between a and b, where a and b are both real numbers. For example, a numerical range of "6 to 22" indicates that all real numbers between "6 to 22" have been listed herein, and "6 to 22" is only a shorthand representation of the combination of these numbers.

The "ranges" disclosed herein may have one or more lower limits and one or more upper limits, respectively, in the form of lower limits and upper limits.

In the present invention, unless otherwise specified, the individual reactions or operation steps may or may not be performed in sequence.

Unless otherwise defined, technical and scientific terms used herein have the same meaning as is familiar to those skilled in the art. In addition, any methods or materials similar or equivalent to those described herein can also be used in the present invention.

According to one aspect of the invention, the invention provides a cosmetic composition for removing acne, which comprises caesalpinia spinosa, sphingomonas ferment product extract, exfoliating agent, oil control agent, bacteriostatic agent, anti-inflammatory agent and soothing and repairing agent.

The exfoliating agent comprises one or more of encapsulated polyfructonic acid, encapsulated azelaic acid and encapsulated salicylic acid, the encapsulated azelaic acid comprising PG6 ACTIVE AA-GLY C; the encapsulated multi-fruit acid comprises SKINPERF LWG;

the anti-inflammatory agent comprises

100 and->

1609; the soothing servicing agent comprises>

100。

Caesalpinia spinosa (Caesalpinia spinosa) gum (also described herein as Caesalpinia spinosa gum) is prepared from Caesalpinia spinosa as raw material, and contains neutral galactomannan as main ingredient, and has advantages of adjustable product sensory quality, safety to human body, and no adverse side effect. The SPHINGOMONAS (sphingamonas) fermentation product extract (also referred to herein as SPHINGOMONAS fermentation product extract) is derived from SPHINGOMONAS, and the fermentation product contains multiple effective components, and can condition skin and delay skin aging.

Although the sphingomonas fermentation product extract can resist acid and strong electrolyte, the extract is added alone, and jelly-like (the whole colloid is easy to incline and slide and does not hang on the wall) is easy to appear at low temperature during stability test. The Caesalpinia spinosa gel belongs to a long-flow thickening agent, is not easy to thicken a system, is poor in thickening performance when being used alone, is not beneficial to preparing essence or gel with higher viscosity, and is easy to rub mud when being added by more than 0.5% alone; the two are compounded for use, can be well complemented, has the effects of acid resistance and electrolyte resistance, can be well thickened, and ensures that the cosmetics do not have the 'jelly-like' property. The sphingomonas ferment product extract and the Caesalpinia spinosa gum are matched with each other and are compounded for use, so that the acid resistance and the electrolyte resistance can be well complemented, the cosmetic composition can be well thickened, and the cosmetic composition, such as cosmetic water and essence water, can be absorbed in the smearing process.

The cosmetic composition also contains an exfoliating agent, an oil control agent, a bacteriostatic agent, an anti-inflammatory agent and a soothing and repairing agent, and has synergistic effects of anti-inflammation, bacteriostasis, oil control and exfoliation in the acne removing direction, so that the obtained composition can achieve the effect of quickly removing acnes.

Exfoliating agents, also known as keratolytic agents, exfoliate the stratum corneum while stimulating the proliferation of epidermal and dermal fibrous tissue, a process of damaging and then repairing the skin barrier. The exfoliating agent comprises one or more of coated multi-fruit acid, coated azelaic acid and coated salicylic acid, the coated azelaic acid comprises PG6 ACTIVE AA-GLY C, the PG6 ACTIVE AA-GLY C comprises the components of polyglycerol-6, azelaic acid and glycine, and the proportion is as follows in sequence: 55. 40:5.

fruit acid is various organic acids extracted from fruits, is a general name of a series of naturally generated organic acids, and is an effective component existing in various natural fruits or yoghourt. The multiple fruit acid refers to a complex composed of at least two fruit acids including at least two of glycolic acid, lactic acid, citric acid, lactobionic acid, malic acid, citrus acid, gluconic acid and tartaric acid, preferably including glycolic acid, lactic acid and citric acid. The coated multiple fruit acid comprises SKINPERF LWG, wherein the coated multiple fruit acid comprises the following components in percentage by weight: 65.1;14.7;7.2;6.3;6.07;0.63.

the encapsulated salicylic acid is optionally Best-

Salicylic acid 30 or BioGenic SA-200.

In some alternative embodiments, the oil control agent comprises one or more of zinc PCA, plankton extract, and lotus japonicus extract, preferably zinc PCA.

The PCA zinc is a product of combination of zinc element and natural moisturizing factor 'Pyrrolidone Carboxylic Acid (PCA)', and the PCA zinc can inhibit grease secretion and inhibit bacterial reproduction. The plankton extract (Tetraselmis subeccica) has effects of activating various physiological activities of skin, promoting metabolism, and enhancing cell resistance. The Lotus CORNICULATUS extract is selected from one or more of Lotus CORNICULATUS flower extract, lotus CORNICULATUS seed extract and Lotus CORNICULATUS root (Lotus japonicas) root nodule extract, and has soothing and moistening effects.

The bacteriostatic agent is mainly used for inhibiting propionibacterium acnes. In some preferred embodiments, the bacteriostatic agent comprises one or more of quaternary ammonium salt-73, caprylyl glycine and white willow bark extract, preferably quaternary ammonium salt-73.

The quaternary ammonium salt-73 has strong antibacterial activity, can destroy the cell membrane of bacterial fungi, has excellent effect on Propionibacterium acnes, can inhibit the formation of melanin, has strong effect and simultaneously has better safety. The caprylyl glycine has antibacterial effect, has strong inhibiting effect on staphylococcus epidermidis, propionibacterium acnes and the like, can inhibit excessive secretion of sebum, and has good affinity to skin. The extract of bark of Salix ALBA (Salix ALBA) contains salicin as main active ingredient, and has antiinflammatory effect.

The anti-inflammatory agent comprises

100 and->

1609。/>

100 (INCI name: bisabolol (and) Ginger Officinale (Ginger) Root Extract) for synthesizing Bisabolol and high puritySynergistic mixtures of extracts of Zingiber officinale. />

1609 (4-tert-Butylcyclohexanol hydroxyl) (INCI name: pentylene Glycol (and) 4-t-Butylcyclohexanol), as a "sensitive regulator", can reduce the loss of calcium in cell membranes and restore the sensitivity of skin to normal level. The anti-inflammatory agent may also optionally include one or more of panthenol, dipotassium glycyrrhizinate, and licorice derivatives. Panthenol has anti-inflammatory, skin conditioning and moisturizing effects. The dipotassium glycyrrhizinate has the functions of resisting inflammation, relieving allergy and regulating immunity. The licorice derivative may be, for example, but not limited to, licorice flavonoid, glycyrrhizic acid, ammonium glycyrrhizinate, dipotassium glycyrrhizinate, disodium glycyrrhizinate, potassium glycyrrhizinate and trisodium glycyrrhizinate, and has good anti-inflammatory effect.

The soothing and repairing agent comprises

100。/>

100 is a skin barrier repair complex. The soothing rejuvenating benefit agent also optionally includes one or more of madecassoside, centella asiatica extract, and ceramide. Madecassoside is a triterpenoid saponin component contained in centella asiatica and has the functions of resisting oxidation, resisting bacteria, regulating immunity and the like. Herba Centellae (CENTELLA ASIATICA) extract has effects of promoting activity of scar fibroblast, whitening skin, removing speckle, sterilizing and resisting inflammation. Ceramide is a lipid present in the skin and plays an important role in the formation of the horny layer of the epidermis, and when the barrier function of the skin is impaired, the skin can restore moisture retention and barrier function by supplementing ceramide.

The cosmetic composition for removing acne comprises 0.01-2.0% of Caesalpinia spinosa gum, for example, but not limited to, 0.01%, 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.45%, 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8% or 2.0%; 0.01-2.0% of sphingomonas fermentation product extract, for example but not limited to, can be 0.01%, 0.05%, 0.1%, 0.15%, 0.2%, 0.22%, 0.25%, 0.3%, 0.4%, 0.45%, 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8% or 2.0%; 0.01 to 10% of an exfoliating agent, for example, but not limited to, 0.01%, 0.05%, 0.1%, 0.5%, 1.0%, 2.0%, 5.0%, 7.5%, 10%; the oil control agent is 0.01 to 1.0%, for example, but not limited to, 0.01%, 0.05%, 0.1%, 0.5%, 1.0%, 2.0%, 5.0%, 7.5%, 10%; 0.001-0.005% of bacteriostatic agent, 0.001%, 0.002%, 0.003%, 0.004% or 0.005%; anti-inflammatory agents 0.01% -2.0%, such as but not limited to 0.01%, 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.45%, 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, or 2.0%; and a soothing conditioner 0.01 to 2.0%, such as but not limited to 0.01%, 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.45%, 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, or 2.0%; the balance is cosmetic matrix.

In some preferred embodiments, the cosmetic composition comprises, in mass percent, caesalpinia spinosa, sphingomonas sp.sphingomonas fermentation product extract, PG6 ACTIVE AA-GLY C (encapsulated azelaic acid), SKINPERF LWG (encapsulated polyfructic acid), zinc PCA, quaternary-7, and,

100、/>

1609 and

100。/>

in some preferred embodiments, the cosmetic composition comprises 0.3-0.5% Caesalpinia spinosa gum, 0.15-0.25% Sphingomonas sp fermentation product extract, PG6 ACTIVE AA-GLY C2%, SKINPERF LWG2%, zinc PCA 0.25%, 0.002-0.003% quaternary ammonium salt-73, 0.002-0.003%,

100 0.2％、/>

16091.0 to 2.0% and->

1001% of a material; the balance is cosmetic matrix.

The cosmetic composition of this embodiment overcomes the disadvantage of the prior art of being not mild enough for anti-acne products. The multiple fruit acids are wrapped, so that the product has stripping performance and simultaneously has the advantage of mildness; PG6 ACTIVE AA-GLY C (encapsulated azelaic acid) is also used, so that the problem of poor water solubility of azelaic acid is overcome, and glycine is also matched in the raw materials, so that the irritation of azelaic acid can be reduced by adding glycine, and the cosmetic composition is milder. The cosmetic composition can be applied on whole face without irritation. Compared with the commercially available cosmetics, the cosmetic composition in the embodiment can quickly and effectively treat the acne, and has the effects of relieving and repairing; the product is fresh and cool without stickiness after use and has wide market application prospect.

It is understood that cosmetic bases acceptable in the art are also included in the cosmetic composition and may be adapted by those skilled in the art according to the dosage form of the cosmetic according to methods well known in the art and as described in various general and more specific text, references, art manuals, commercial instructions and standard documents. The cosmetic base includes, but is not limited to, one or more of solvents, surfactants, solubilizers, thickeners, skin conditioning agents, moisturizers, oils, preservatives, chelating agents, and fragrances, preferably including conditioning agents, moisturizers, oils, preservatives, and chelating agents.

In some preferred embodiments, the solvent includes a solvent that primarily or secondarily dissolves each component, and the solvent may be selected from organic solvents or inorganic solvents, preferably deionized water as a primary solvent of the cosmetic composition.

Emulsifiers are also encompassed by the surfactants described herein, and in some preferred embodiments, the surfactants preferably include, but are not limited to, sodium stearoyl glutamate, MONTANOVTML, olivem1000, and

165 CN.

In some preferred embodiments, the humectant comprises a polyhydric alcohol including, but not limited to, one or more of glycerol, 1, 2-hexanediol, and 1, 3-propanediol.

In some preferred embodiments, the grease comprises

One or more of Ultimate (INCI name: undecanoe (and) Tridecanoe), isononyl isononanoate and dimethicone kf-96A-6T. Isononyl isononanoate has a high spreading coefficient of 1400mm ² About/10 min, is relatively fresh and cool and is suitable for being used as a substrate of refreshing cosmetics; />

The spreadability of Ultimate reaches 2500mm ² The oil has the characteristics of easiness in spreading, no greasiness, easiness in absorption, dryness and smoothness, is suitable for being used as a substrate of refreshing cosmetics, is particularly suitable for acne-removing products, so that the greasiness of the products is reduced, the products are not sticky, the skin is ventilated, no extra burden is added to acne muscles, and when milk or frost is prepared, the oil is selected from the extremely refreshing blood vessel>

Ultimate, particularly suitable for vaccinia muscle.

In some preferred embodiments, the preservative includes, but is not limited to, one or more of p-hydroxyacetophenone, p-hydroxybenzoic acid, potassium sorbate, benzyl alcohol, sodium benzoate, methyl paraben, phenoxyethanol, chlorphenesin, and benzoic acid, preferably including p-hydroxyacetophenone.

In some preferred embodiments, the chelating agent includes, but is not limited to, one or more of disodium EDTA, tetrasodium EDTA, dipotassium EDTA, tripotassium EDTA, and sodium phytate.

In some preferred embodiments, the pH adjusting agent includes, but is not limited to, one or more of arginine, sodium hydroxide, potassium hydroxide, triethanolamine, citric acid, sodium citrate, succinic acid, disodium succinate, disodium hydrogen phosphate, sodium dihydrogen phosphate, aminomethyl propanol, and aminomethyl propanediol.

In some preferred embodiments, the solubilizing agent comprises one or more of PEG-60 hydrogenated castor oil, PEG-40 hydrogenated castor oil, and PPG-26-Butaneth-26.

In some preferred embodiments, the cosmetic base comprises glycerin, disodium EDTA, 1, 2-hexanediol, p-hydroxyacetophenone, and 1, 3-propylene glycol.

In other preferred embodiments of the present invention, the, the cosmetic matrix comprises glycerol, sodium stearyl glutamate, EDTA disodium, stearyl alcohol, simethicone kf-96A-6T,

Ultimate、/>

165CN, montanov L, 1, 2-hexanediol, p-hydroxyacetophenone and 1, 3-propanediol.

In some preferred embodiments, the formulation of the cosmetic composition is as follows: comprises 0.3 to 0.5 percent of Caesalpinia Spinosa gum, 0.15 to 0.25 percent of Sphingomonas sp fermentation product extract, 2 percent of PG6 ACTIVE AA-GLY C, 2 percent of SKINPERF LWG, 0.25 percent of PCA zinc, 0.003 percent of quaternary ammonium salt-73.003 percent,

100 0.2％、/>

16091.0% and +>

100 1％；

Also contains a cosmetic matrix, wherein the cosmetic matrix comprises 3% of glycerin, 0.02% of EDTA disodium, 0.5% of 1, 2-hexanediol, 0.5% of p-hydroxyacetophenone and 3% of 1, 3-propylene glycol; also comprises a pH regulator, a solubilizer and the balance of deionized water.

In other preferred embodiments, the cosmetic composition is formulated as follows: comprises (by mass percent) Caesalpinia spinosa Gum 0.3-0.45%, sphingomonas sphingomonas fermentation product extract 0.15-0.22%, PG6 ACTIVE AA-GLY C2%, SKINPERF LWG2%, PCA zinc 0.25%, quaternary ammonium salt-73.002%,

100 0.2％、/>

16091.2% and +>

100 1％；

Also contains a cosmetic matrix, wherein the cosmetic matrix comprises 3 percent of glycerol, 0.2 percent of sodium stearyl glutamate, 0.05 percent of EDTA disodium, 3 to 5 percent of stearyl alcohol, 1 percent of dimethicone kf-96A-6T,

Ultimate 5％、/>

165CN 1%, montanov L1%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5% and 1, 3-propanediol 3%; also comprises a pH regulator, essence and the balance of deionized water.

The cosmetic composition of the embodiment is acne-removing essence milk or essence cream, the oil with high spreading coefficient and refreshing property is selected, the prepared emulsion or cream has good ductility and high absorption speed, is not sticky after being absorbed, and is particularly suitable for acne muscle. Only adding kf-96A-6T and

the Ultimate ensures that the product has the characteristics of easy spreading, no greasiness, easy absorption and dryness, and the essential milk or the essential cream has an absorbed feeling in the smearing process by matching with the composition for thickening provided by the invention, has no residual feeling after smearing and is dry and comfortable, which is difficult to achieve by other similar acne-removing products. Dimethicone kf-96A-6T and->

Ultimate is fresh oil, and dimethicone kf-96A-6T can solve the problem of fatty alcohol whitening strip (white stripes on the skin surface in body coating), and/or>

The Ultimate can make the prepared emulsion or cream fresh and cool, breathable and non-sticky, and is particularly suitable for acne-removing products, which is difficult to achieve by other similar products.

The dosage form of the cosmetic composition for removing acne provided by the invention preferably comprises water, emulsion, cream or gel. The cosmetic composition for removing acne may be, for example, but not limited to, a lotion, a toner, a serum, a lotion, a cream, a serum, a gel, a spray, a mask, a skin foundation, a paint-on mask, a patch mask, or the like, in a general classification of well-known, mature commercial products.

According to another aspect of the present invention, there is also provided a process for the preparation of the above cosmetic composition comprising mixing the ingredients in the amounts specified.

In some preferred embodiments, the preparation method comprises: respectively dissolving the bacteriostatic agent and the oil control agent; dispersing the cosmetic thickened composition containing the corium versicolor and the sphingomonas fermentation product extract in a solvent, then mixing the dissolved or dispersed systems, adding the other components, and uniformly mixing to obtain the cosmetic composition.

In some preferred embodiments, the preparation method comprises: dissolving quaternary ammonium salt-73 in polyalcohol to obtain a first system, wherein the temperature of the polyalcohol is preferably 60-75 ℃, and more preferably 65-75 ℃; dissolving PCA zinc into a part of formula amount of deionized water to obtain a second system, wherein the temperature of the part of formula amount of deionized water is preferably 50-60 ℃; dispersing the fermentation product of the caesalpinia spinosa and the sphingosine monad in the rest deionized water to obtain a third system, then uniformly mixing the first system, the second system, the third system and the rest components to obtain the cosmetic composition, wherein preferably, the extract of the fermentation product of the caesalpinia spinosa and the sphingosine monad, which is uniformly dispersed in the rest ionized water, is heated to 82-88 ℃, is continuously homogenized for 5-10 min, is cooled to 50-55 ℃, and is then mixed with other components.

In some preferred embodiments, the preparation method comprises the steps of:

step (a): mixing and dissolving quaternary ammonium salt-73 and 1, 3-propylene glycol at 65-75 ℃;

step (b): mixing PCA zinc with deionized water at 50-60 ℃ until the PCA zinc is dissolved;

step (c): dissolving p-hydroxyacetophenone in 1, 2-hexanediol at 55-60 ℃;

a step (d): mixing

100、/>

1609、/>

100 and a solubilizer;

a step (e): dispersing the mixture of Caesalpinia spinosa and Sphingomonas sphingomonas fermentation product extract in the deionized water of the rest formula amount;

step (f): heating the material body in the step (e) to 82-88 ℃, adding glycerol and EDTA disodium, continuing homogenizing for 5-10 min, and uniformly stirring;

step (g): cooling the material body in the step (f) to 50-55 ℃, adding the products in the steps (a), (b), (c) and (d), and adding the coated multiple fruit acid and the coated azelaic acid; after the pH value is adjusted, the mixture is stirred evenly.

In some preferred embodiments, the preparation method comprises the steps of:

step (a): mixing and dissolving quaternary ammonium salt-73 and 1, 3-propylene glycol at 65-75 ℃;

step (b): mixing zinc PCA with deionized water at 50-60 ℃ until the zinc PCA is dissolved;

step (c): dissolving p-hydroxyacetophenone in 1, 2-hexanediol at 55-60 ℃;

step (d): mixing

100、/>

1609、/>

100 and a solubilizer;

a step (e): dispersing the mixture of Caesalpinia spinosa and Sphingomonas sphingomonas fermentation product extract in the deionized water of the rest formula amount;

step (f): heating the material body obtained in the step (e) to 82-88 ℃, adding glycerol, EDTA disodium and sodium stearoyl glutamate, continuing homogenizing for 5-10 min, and then uniformly stirring;

step (g): stearyl alcohol, dimethyl silicone oil kf-96A-6T,

Ultimate、/>

165CN and Montanov L are heated to 82-88 ℃ until all the components are completely dissolved;

a step (h): adding the product obtained in the step (g) into the step (f), homogenizing, and then keeping the temperature and stirring;

step (i): and (c) cooling the product obtained in the step (h) to 50-55 ℃, adding the products obtained in the step (a), the step (b) and the step (c), adding the coated multiple fruit acid and the coated azelaic acid, adjusting the pH value, and uniformly stirring.

It is understood that the above steps may be performed sequentially or not, or that several of the steps, such as steps (a) - (c), may be performed simultaneously, or in any order.

The technical scheme and the technical effect of the invention are further explained by combining the preferred embodiments.

Example 1

The embodiment provides a cosmetic composition, which can be used as a toning lotion and comprises the following components:

caesalpinia Spinosa (Caesalpinia Spinosa) gum, sphingomonas (Sphingomonas) fermentation product extract, coated azelaic acid, coated multi-fruit acid, zinc PCA, quaternary ammonium salt-73, and/or zinc oxide,

100、/>

1609 and +>

100, respectively; also contains cosmetic base including deionized water, glycerin, disodium EDTA, 1, 2-hexanediol, p-hydroxyacetophenone, 1, 3-propanediol, arginine, sodium hydroxide and PEG-40 hydrogenated castor oil, wherein the encapsulated azelaic acid is selected from PG6 ACTIVE AA-GLY C and the encapsulated polycarpic acid is selected from SKINPERF LWG. The contents of the components are shown in table 1.

The cosmetic composition of this example was prepared by the following method:

step (a): heating 1, 3-propylene glycol to 65-75 ℃, adding quaternary ammonium salt-73, and continuously stirring until the quaternary ammonium salt-73 is completely dissolved.

Step (b): adding 3% deionized water, heating to 50-60 deg.C, adding PCA zinc, and stirring until it is completely dissolved.

Step (c): heating 1, 2-hexanediol to 55-60 ℃, adding p-hydroxyacetophenone, and continuously stirring until the p-hydroxyacetophenone is completely dissolved;

step (d): will be provided with

100、/>

1609 and +>

100, adding into a beaker, adding a proper amount of PEG-40 hydrogenated castor oil, and uniformly stirring.

A step (e): adding the rest deionized water in the formula into a beaker, starting a homogenizer, adding the mixture of the Caesalpinia spinosa gum and the sphingosine monad fermentation product extract, homogenizing for 8min, continuously stirring, dispersing to be homogeneous, and checking until no particle agglomeration exists.

Step (f): and (e) heating the material body in the step (e) to 82-88 ℃, adding glycerol and EDTA disodium, continuing homogenizing for 5min, and uniformly stirring.

A step (g): cooling the material body in the step (f) to 50-55 ℃, adding the products in the steps (a), (b), (c) and (d), and adding the coated multiple fruit acid and the coated azelaic acid; using a small amount of arginine or sodium hydroxide pre-dissolved by water to adjust the pH value to 4.5-5.5, stirring evenly and cooling to room temperature.

Example 2

This example provides a cosmetic composition containing the same components as in example 1, differing from example 1 in the content of the components differing from example 1, the contents of the components being shown in table 1. The preparation procedure is the same as example 1, and the formulations are prepared according to the formula amounts shown in Table 1. The cosmetic composition provided in this example can be used as an essence, and the main difference from example 1 is that the viscosity of example 2 is relatively high.

Comparative example 1

Comparative example 1 compared with example 1, the inclusion of multiple fruit acids is not included, and the contents of the components are shown in table 1. The procedure is as in example 1 except that in step (g) the amount of formulated polycarpic acid is not encapsulated as in Table 1.

Comparative example 2

Comparative example 2 compared to example 1, which contained no encapsulated azelaic acid, the amounts of the components are shown in table 1. Preparation procedure example 1 except that step (g) was made without the inclusion of encapsulated azelaic acid and formulated in the amounts shown in Table 1.

Comparative example 3

Comparative example 3 does not contain the quaternary ammonium salt-73 as compared with example 1, and the contents of the respective components are shown in Table 1. The preparation procedure differed from example 1 only in that step (a) was not included and the formulation amounts were as given in table 1.

Comparative example 4

Comparative example 4 contains no zinc PCA and the amounts of the components are shown in Table 1, compared with example 1. The preparation procedure differed from example 1 only in that step (b) was not included and the formulation amounts were as given in table 1.

Comparative example 5

Comparative example 5 compared with example 1, the preparation method does not contain the sphingomonas fermentation product extract, the content of each component is shown in table 1, and the preparation steps are different from example 1 only in that the sphingomonas fermentation product extract is not added in step (e) and the preparation is carried out according to the formula amount shown in table 1.

Comparative example 6

Comparative example 6 does not contain Caesalpinia spinosa gum compared with example 1, the content of each component is shown in table 1, and the preparation steps are different from example 1 only in that no Caesalpinia spinosa gum is added in step (e) and the formula amount is prepared according to table 1.

TABLE 1 EXAMPLES 1 TO 2 AND COMPARATIVE EXAMPLES 1 to 6 each contain the component

The content of each component in table 1 is mass percent based on the total mass of the cosmetic composition.

Example 3

The embodiment provides a cosmetic composition, which can be used as essence milk and comprises the following components:

caesalpinia Spinosa, sphingomonas (Sphingomonas) fermentation product extract, encapsulated azelaic acid, encapsulated multi-fruit acid, zinc PCA, quaternary ammonium salt-73, and/or a mixture thereof,

100、/>

1609 and +>

100；

Also contains cosmetic matrix, which comprises deionized water, glycerol, sodium stearyl glutamate, disodium EDTA, stearyl alcohol, dimethicone kf-96A-6T,

Ultimate、/>

165CN, montanov L, arginine, 1, 2-hexanediol, p-hydroxyacetophenone, 1, 3-propanediol, PEG-40 hydrogenated castor oil and essence, wherein the encapsulated azelaic acid is selected from PG6 ACTIVE AA-GLY C and the encapsulated multiple fruit acid is selected from SKINPERF LWG. The contents of the components are shown in table 2. />

The preparation method of the cosmetic composition of the present example was:

step (a): heating 1, 3-propylene glycol to 65-75 ℃, adding quaternary ammonium salt-73, and continuously stirring until the quaternary ammonium salt-73 is completely dissolved.

Step (b): adding 3% deionized water, heating to 50-60 deg.C, adding PCA zinc, and stirring until it is completely dissolved.

Step (c): heating 1, 2-hexanediol to 55-60 ℃, adding p-hydroxyacetophenone, and continuously stirring until the p-hydroxyacetophenone is completely dissolved.

Step (d): will be provided with

100、/>

1609 and +>

100, adding into a beaker, adding a proper amount of PEG-40 hydrogenated castor oil, and uniformly stirring.

A step (e): adding the rest deionized water in the formula into a beaker, starting a homogenizer, adding the spinosad and the sphingosine monad fermentation product extract, homogenizing for 8-10 min, continuously stirring, dispersing until the mixture is homogenized, and checking until no particle agglomeration exists.

Step (f): heating the material body in the step (e) to 82-88 ℃, adding glycerol, EDTA disodium and stearyl sodium glutamate, continuing homogenizing for 5min, and then preserving heat and stirring uniformly.

Step (g): stearyl alcohol, dimethyl silicone oil kf-96A-6T,

Ultimate、/>

165CN and Montanov L are heated to 82-88 ℃ until no particles are completely dissolved.

A step (h): and (e) adding the product obtained in the step (g) into the step (f), homogenizing for 6min, and stirring for 5min under the condition of heat preservation.

Step (i): and (c) cooling the product obtained in the step (h) to 50-55 ℃, adding the product obtained in the step (a), the step (b) and the step (c), adding the coated multiple fruit acid, the coated azelaic acid and a small amount of water pre-dissolved arginine, adjusting the pH value to 4.5-5.5, uniformly stirring and cooling to room temperature.

Example 4

This example provides a cosmetic composition containing the same components as in example 3, except that the content of the components is different from that of example 3, and the content of each component is shown in table 2. The preparation steps are the same as example 3, and the formula amounts are prepared according to the table 2. The cosmetic composition provided by the embodiment can be used as essence cream.

Example 5

This example provides a cosmetic composition comprising ingredients that differ from those of example 3 in not containing

Ultimate, also containing isononyl isononanoate. The preparation step differs from example 3 only in that step (g) is not supplemented ` Harbin `>

Ultimate, and isononyl isononanoate was added and formulated in the amounts as shown in table 2.

Example 6

This example provides a cosmetic composition comprising the components different from those of example 3 in that it does not contain Montanov L and further comprises olivim 1000. The preparation procedure differs from example 3 only in that step (g) is carried out without Montanov L, but with OLIVEM1000, formulated according to the formulation amounts shown in Table 2.

Comparative example 7

Comparative example 7 differs from example 3 in the components contained therein that the thickener contained no Sphaerotheca spinosa and sphingomonas fermentation product extract, and sodium polyacryloyldimethyltaurate was used, the preparation procedure differing from example 3 only in step (e), homogeneous sodium polyacryloyldimethyltaurate, formulated in the amounts specified in table 2.

Comparative example 8

Comparative example 8 differs from example 3 in the components contained therein in that the thickener contained no Sphaerotheca spinosa and Sphingomonas fermentation product extract, instead of polyacrylate crosspolymer-6, and the preparation procedure differed from example 3 only in step (e), homogeneous polyacrylate crosspolymer-6, formulated in the amounts specified in Table 2.

TABLE 2 contents of components of examples 3 to 6 and comparative examples 7 to 8

Effect example 1

Skin feel test and efficacy assessment test:

the number of the testees is 32, the number of the testees is 2, the number of the effective people is 30, the testees are healthy Asian people, the skin types are not limited, and the skin is accompanied with acne vulgaris.

Testing sampling time points: d0 (before sample use) and D7 (day 7 after use), mode of use: the evaluation method is questionnaire survey, once in the morning and once in the evening.

(1) Comparative examples 1 to 4 and example 1 were evaluated, and the indexes tested were: soothing/non-irritating, oil control, acne improving, skin satisfaction were evaluated. Comparing 1-4 with the skin feeling test and the efficacy evaluation test of the embodiment 1, counting the number of people who are satisfied or relatively satisfied with the four test indexes; the effect was considered to be general or not, and none was considered to be effective, and no count was made. The test results are shown in table 3:

table 3 skin feel test and efficacy evaluation test satisfaction demographics (effective 30 persons) for comparative examples 1 to 4 and example 1

It was found that the test population was satisfactory for soothing/non-irritating, oil control, acne improvement, skin feel satisfaction of example 1. As can be seen from the results in table 3, the composition of the present invention has a synergistic effect, and has more obvious effects of removing acne, controlling oil and being more soothing/non-irritating through the synergistic effect among the compositions.

(2) The skin feel of the control example 8, the example 3, the example 5 and the example 6 was evaluated by a score system, and the score was 1 to 5, and the higher the score, the higher the score was: the better the spreadability; the better the soft and smooth feel; the faster the absorption speed; the less viscous feeling is when the paste is applied; the smaller the viscous feeling after smearing; the data obtained were averaged and subjected to data analysis as shown in table 4:

table 4 skin feel evaluation results of comparative example 8, example 3, example 5, and example 6

Sample set	Spreadability	Feeling of softness and smoothness	Absorption rate	Sticky feeling during application	Sticky feeling after application
						Comparative example 8	3.01	3.02	3.12	2.52	2.62
Example 5	3.85	3.89	3.65	3.85	3.82
						Example 6	3.32	3.53	3.84	3.92	3.56
Example 3	4.63	4.52	4.15	4.22	4.35

Experiments show that in the comparative example 8, the coating is more sticky during and after the coating; the freshness and absorption during application were significantly slower for examples 5 and 6; it can be seen from Table 4 that the test population was satisfactory in spreading, smooth feeling, absorption speed, stickiness upon application, and stickiness after application of the sample of example 3.

Effect example 2

And (3) testing the efficacy:

the referenced test method was: the test method comprises the following steps of 'T/CNMIA 0012-2020 clinical evaluation standard of acne-removing efficacy skin care products', 'T/TDCA 004-2021 cosmetic acne-removing efficacy test method', 'T/ZHCA 002-2018 cosmetic oil-controlling efficacy test method', 'QB/T4256-2011 cosmetic moisturizing efficacy evaluation guideline' and 'T/ZHCA 003-2018 cosmetic influence skin moisture loss test method'.

The skin prick and patch tests were passed before the sample test, indicating that the test product was very mild.

The samples were tested for stratum corneum moisture content, transepidermal water loss, skin gloss, skin oil content, facial pore area ratio, facial red area a value, facial pox number, respectively.

And (3) moisturizing: the higher the test value is, the higher the moisture content of the skin stratum corneum is; relieving and repairing: the lower the test value is, the better the skin barrier function is; controlling oil: the lower the test value is, the smaller the oil secretion is; removing acne: the smaller the number of facial acne, the better; the smaller the value of facial redness area a, the less the degree of skin redness.

The relevant test instruments are as follows:

1) And (3) testing the moisture content: by means of probes

CM 825 measures the skin moisture content values at each test time point, three times per test area.

2) And (3) testing the water dispersion loss of the epidermis: by means of probes

TM Hex measures the value TEWL (g/m) of the percutaneous water loss at each test time point respectively ² H), three times per test area.

3) Testing the oil content of the skin: by means of probes

SM 815 separately measured the skin oil content at each test time point, three times per test area.

4) Skin erythema index a value: a skin Image taking instrument VISIA-CR is used for taking standard white light and UV light standard images, and an analysis system Image-Pro Plus is used for analyzing the facial pore area ratio and the red area a value.

5) Area ratio of acne: a skin Image taking instrument VISIA-CR is used for taking an Image of a subject, and an analysis system Image-Pro Plus is used for analyzing the acne area ratio.

After the test subject uses the product, the change result of any one of the parameters of moisturizing, repairing, oil controlling and acne removing of the instrument test or image analysis is obviously improved (P is less than 0.05) compared with the result before the test subject uses the product, and the test product is determined to have the effects of moisturizing, soothing, repairing and acne removing.

The efficacy test results of the cosmetic composition provided in example 3 are shown in table 5, and the acquisition graphs of red zone at 0, 14 and 28 days of the test are shown in fig. 1, in which a is D0, B is D14 and C is D28.

Table 5 results of the efficacy testing of example 3

/>

As can be seen from table 5, the moisture content of stratum corneum in the tested area of the subject's face increased significantly after 14 days with the product of example 3 and 28 days with the product; the water loss rate of the skin through the epidermis is obviously reduced, the oil content of the skin is obviously reduced, the erythema index a value of the skin is obviously reduced, and the area ratio of acne is obviously reduced. It can be seen from fig. 1 that acne can be improved, the area of pimples can be reduced and inflammation can be improved by using the product of example 3. The above experimental results show that the product of embodiment 3 has the effects of moisturizing, soothing, repairing, controlling oil and removing acne.

Effect example 3 stability test

The stability test was: placing the samples in an incubator with-18 ℃, 4 ℃, 40 ℃, 45 ℃ and a cold-hot cycle respectively, taking out the samples from each temperature at the time of 1 week, 2 weeks, 4 weeks, 8 weeks and 12 weeks, and observing whether the samples have abnormal conditions or not: at any time and at any temperature, if the product is abnormal in precipitation, delamination, discoloration, taste change, and viscosity change (more than 50% from the initial value), the product is recorded as "failed" if any abnormality occurs, and the others as "normal". The test results are shown in table 6 and fig. 2:

table 6 stability test results

As can be seen from the experimental results shown in table 6, the cosmetic composition provided in this example has good stability, and has no abnormal defects of precipitation, delamination, discoloration, odor change and viscosity change under the conditions of-18 ℃ to 45 ℃ and cold and hot cycles. In comparative example 7, delamination occurred during the high temperature test, in comparative example 8, a severe viscosity reduction occurred, and in examples 1 to 6, no abnormality was observed in the stability test. Fig. 2 is a graph of stability test showing that the left panel is the cosmetic composition provided in example 3 and the right panel is comparative example 7, and it can be seen that the comparative example 7 is delaminated at a high temperature.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and these modifications or substitutions do not depart from the spirit of the corresponding technical solutions of the embodiments of the present invention.

Claims (10)

1. A cosmetic composition for removing acne is characterized by comprising, by mass, 0.01-2.0% of Caesalpinia spinosa Gum, 0.01-2.0% of Sphingomonas sp fermentation product extract, 0.01-10% of exfoliating agent, 0.01-1.0% of oil control agent, 0.001-0.005% of bacteriostatic agent, 0.01-2.0% of anti-inflammatory agent and 0.01-2.0% of soothing and repairing agent; the balance of cosmetic base material;

the exfoliating agent comprises one or more of encapsulated polyfructonic acid, encapsulated azelaic acid and encapsulated salicylic acid, the encapsulated azelaic acid comprising PG6 ACTIVE AA-GLY C; the encapsulated multiple fruit acids comprise SKINPERF LWG;

the anti-inflammatory agent comprises

100 and->

1609；

The soothing and repairing agent comprises

100。

2. The cosmetic composition of claim 1, wherein the exfoliating agent comprises PG6 ACTIVE AA-GLY C and skinrf LWG;

preferably, the oil control agent comprises one or more of zinc PCA, plankton extract and lotus japonicus extract, preferably zinc PCA;

preferably, the bacteriostatic agent comprises one or more of quaternary ammonium salt-73, caprylyl glycine and white willow bark extract, preferably quaternary ammonium salt-73;

preferably, the anti-inflammatory agent further comprises one or more of panthenol, dipotassium glycyrrhizinate, and licorice derivatives;

preferably, the soothing and repairing agent further comprises one or more of madecassoside, centella asiatica extract and ceramide;

preferably, the cosmetic composition for removing acne has a pH of 4.5 to 6.0, preferably 4.5 to 5.5.

3. The cosmetic composition of claim 2, wherein said cosmetic composition comprises Caesalpinia spinosa, sphingomonas sp

100、/>

1609 and +>

100；

Preferably, the cosmetic composition comprises 0.3-0.5% of Caesalpinia spinosa gum, 0.15-0.25% of Sphingomonas sp fermentation product extract, 2% of PG6 ACTIVE AA-GLY C, 2% of SKINPERF LWG, 0.25% of zinc PCA, 0.002-0.003% of quaternary ammonium salt-73,

100 0.2％、/>

16091.0 to 2.0% and

1001 percent; the balance is cosmetic matrix.

4. The cosmetic composition of claim 1, wherein the cosmetic base comprises one or more of a solvent, a surfactant, a solubilizer, a thickener, a skin conditioner, a lipid, a humectant, a preservative, a chelating agent, a pH adjuster, and a fragrance;

preferably, the surfactant comprises an emulsifier;

preferably, the surfactant comprises sodium stearoyl glutamate, MONTANOV ^TM L, OLIVEM1000 and

165 One or more of CN;

preferably, the humectant comprises a polyol;

preferably, the polyol comprises one or more of glycerol, 1, 2-hexanediol, and 1, 3-propanediol;

preferably, the grease comprises

One or more of Ultimate, isononyl isononanoate and simethicone kf-96A-6T;

preferably, the preservative comprises one or more of p-hydroxyacetophenone, p-hydroxybenzoic acid, potassium sorbate, benzyl alcohol, sodium benzoate, methyl paraben, phenoxyethanol, chlorphenesin, and benzoic acid;

preferably, the chelating agent comprises one or more of disodium EDTA, tetrasodium EDTA, dipotassium EDTA, tripotassium EDTA, and sodium phytate;

preferably, the pH adjuster comprises one or more of arginine, sodium hydroxide, potassium hydroxide, triethanolamine, citric acid, sodium citrate, succinic acid, disodium succinate, disodium hydrogen phosphate, sodium dihydrogen phosphate, aminomethyl propanol, and aminomethyl propanediol;

preferably, the solubilizer comprises one or more of PEG-60 hydrogenated castor oil, PEG-40 hydrogenated castor oil and PPG-26-Butaneth-26;

preferably, the solvent comprises an organic solvent and/or an inorganic solvent, preferably comprises deionized water;

preferably, the cosmetic base comprises glycerin, disodium EDTA, 1, 2-hexanediol, p-hydroxyacetophenone, and 1, 3-propanediol;

preferably, the cosmetic base comprises glycerin, sodium stearyl glutamate, disodium EDTA, stearyl alcohol, dimethicone kf-96A-6T,

Ultimate、/>

165CN, montanov L, 1, 2-hexanediol, p-hydroxyacetophenone and 1, 3-propanediol.

5. The cosmetic composition of claim 1, wherein the cosmetic composition is an aqueous, emulsion, cream, or gel;

preferably, the cosmetic composition is a lotion, a toner, an essence lotion, an emulsion, a cream, an essence lotion, a gel, a spray, a mask, a skin base solution, a face pack or a patch mask.

6. The cosmetic composition according to any one of claims 1 to 5, comprising, in mass%, from 0.3 to 0.5% of Caesalpinia spinosa gum, from 0.15 to 0.25% of a sphingomonas sp

100 0.2％、/>

16091.0% and +>

100 1％；

Also contains cosmetic matrix, wherein the cosmetic matrix comprises 3% of glycerol, 0.02% of EDTA disodium, 0.5% of 1, 2-hexanediol, 0.5% of p-hydroxyacetophenone and 3% of 1, 3-propylene glycol; also comprises pH regulator and solubilizer, and the balance is deionized water.

7. The cosmetic composition according to any one of claims 1 to 5, comprising, in mass%, caesalpinia spinosa gum 0.3 to 0.45%, sphingomonas sp fermentation product extract 0.15 to 0.22%, PG6 ACTIVE AA-GLY C2%, SKINPERF LWG2%, zinc PCA 0.25%, quaternary ammonium salt-73.002%,

100 0.2％、/>

16091.2% and +>

100 1％；

Also comprises a cosmetic matrix, wherein the cosmetic matrix comprises,the cosmetic base material comprises 3% of glycerol, 0.2% of sodium stearyl glutamate, 0.05% of EDTA disodium, 3-5% of stearyl alcohol, 1% of kf-96A-6T simethicone,

Ultimate 5％、/>

165CN 1%, montanov L1%, 1, 2-hexanediol 0.5%, p-hydroxyacetophenone 0.5% and 1, 3-propanediol 3%;

also comprises pH regulator and essence, and the balance is deionized water.

8. A process for preparing a cosmetic composition according to any one of claims 1 to 7, comprising mixing the components in the amounts formulated;

preferably, the preparation method comprises: respectively dissolving the bacteriostatic agent and the oil control agent; dispersing the Spindaea spinosa and the sphingosine monad fermentation product extract in a solvent, mixing the dissolved or dispersed systems, adding the other components, and uniformly mixing to obtain the cosmetic composition;

preferably, the preparation method comprises:

dissolving quaternary ammonium salt-73 in polyalcohol to obtain a first system; dissolving PCA zinc in part of deionized water according to the formula amount to obtain a second system; dispersing the fermentation product of the Caesalpinia spinosa and the sphingosine monad in the residual deionized water to obtain a third system;

uniformly mixing the first system, the second system, the third system and the rest components to obtain the cosmetic composition;

preferably, quaternary ammonium salt-73 is dissolved in polyol at 60-75 ℃ to obtain the first system;

preferably, quaternary ammonium salt-73 is dissolved in polyol at 65-75 ℃ to obtain the first system;

preferably, the zinc PCA is dissolved in part formula amount of deionized water at 50-60 ℃ to obtain the second system;

preferably, the Caesalpinia spinosa and the sphingosine monad fermentation product extract which are uniformly dispersed in the residual deionized water are heated to 82-88 ℃, are continuously homogenized for 5-10 min, are cooled to 50-55 ℃, and are mixed with other components.

9. A method of preparing the cosmetic composition of claim 6, comprising:

a step (a): mixing and dissolving quaternary ammonium salt-73 and 1, 3-propylene glycol at 65-75 ℃;

step (b): mixing PCA zinc with deionized water at 50-60 ℃ until the PCA zinc is dissolved;

step (c): dissolving p-hydroxyacetophenone in 1, 2-hexanediol at 55-60 ℃;

step (d): mixing

100、/>

1609、/>

100 and a solubilizer;

a step (e): dispersing the mixture of Caesalpinia spinosa and Sphingomonas sphingomonas fermentation product extract in the deionized water of the rest formula amount;

step (f): heating the material body in the step (e) to 82-88 ℃, adding glycerol and EDTA disodium, continuing homogenizing for 5-10 min, and uniformly stirring;

step (g): cooling the material body in the step (f) to 50-55 ℃, then adding the products in the steps (a), (b), (C) and (d), and adding PG6 ACTIVE AA-GLY C, SKINPERF LWG; after the pH value is adjusted, the mixture is stirred evenly.

10. A method of preparing a cosmetic composition according to claim 7, comprising:

a step (a): mixing and dissolving quaternary ammonium salt-73 and 1, 3-propylene glycol at 65-75 ℃;

step (b): mixing PCA zinc with deionized water at 50-60 ℃ until the PCA zinc is dissolved;

a step (c): dissolving p-hydroxyacetophenone in 1, 2-hexanediol at 55-60 ℃;

a step (d): mixing

100、/>

1609、/>

100 and a solubilizer;

a step (e): dispersing the mixture of Caesalpinia spinosa and Sphingomonas sphingomonas fermentation product extract in the deionized water of the rest formula amount;

a step (f): heating the material body obtained in the step (e) to 82-88 ℃, adding glycerol, EDTA disodium and sodium stearoyl glutamate, continuing homogenizing for 5-10 min, and then uniformly stirring;

step (g): stearyl alcohol, dimethyl silicone oil kf-96A-6T,

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165CN and Montanov L are heated to 82-88 ℃ until all the components are completely dissolved;

a step (h): adding the product obtained in the step (g) into the step (f), homogenizing, and then keeping the temperature and stirring;

step (i): and (d) cooling the product obtained in the step (h) to 50-55 ℃, adding the products obtained in the step (a), the step (b), the step (C) and the step (d), adding PG6 ACTIVE AA-GLY C and SKINPERF LWG, adjusting the pH value, and uniformly stirring.

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