CN112494355A - Moisturizing composition and preparation method thereof - Google Patents
Moisturizing composition and preparation method thereof Download PDFInfo
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- CN112494355A CN112494355A CN202011399919.4A CN202011399919A CN112494355A CN 112494355 A CN112494355 A CN 112494355A CN 202011399919 A CN202011399919 A CN 202011399919A CN 112494355 A CN112494355 A CN 112494355A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a moisturizing composition, which comprises the following components: butanediol; glyceryl polyether-26; isononyl isononanoate; behenyl alcohol; polydimethylsiloxane; betaine; octyl methicone; PEG-12 polydimethylsiloxane/PPG-20 crosspolymer; cetostearyl alcohol; coco glucoside; sodium acrylate/sodium acryloyldimethyl taurate copolymers; isohexadecane; polysorbate-80; carbomer; p-hydroxyacetophenone; a pH adjusting agent; a preservative; a chelating agent; a fragrance; a skin conditioning agent; and (3) water. The invention combines a plurality of skin conditioners which are beneficial to skin absorption and improve the skin state with water, butanediol, isononyl isononanoate, pH regulator and other components, so that the skin conditioner is easier to skin absorption, moistens the skin, reduces water loss, improves skin wrinkles, strengthens the skin elasticity, makes the appearance ruddy, accelerates the absorption of nutrition and improves the skin state.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a moisturizing composition and a preparation method thereof.
Background
Women have many problems with their age, such as the skin being easily tanned, and color spots around the eyes, often times feeling taut, lack of radiance, less elastic, and sometimes finding fine wrinkles around the corners and nose. In addition, the skin is damaged greatly by external environment, for example, the skin is damaged greatly by external oxidation and sunlight, pores are easily blocked by dust, melanin is formed by ultraviolet rays, the face is stained, the urban air pollution is serious, and harmful substances in the air certainly damage the skin to a great extent.
At present, cosmetics on the market have uneven quality, and in order to achieve the purpose of quick response, ineffectual merchants can add prohibited drugs such as hormone at will to cause skin damage, which is comprehensively expressed by yellow and rough complexion, hypoelasticity, skin atrophy, wrinkle appearance, pigmentation, sensitive skin, inflammation and the like.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides a moisturizing composition which can moisturize the skin, reduce water loss, improve skin wrinkles, strengthen skin elasticity, make the appearance ruddy, accelerate nutrient absorption and improve the skin state.
The invention also provides a preparation method of the moisturizing composition.
The invention is realized by adopting the following technical scheme:
the moisturizing composition comprises the following components in parts by weight:
4-8 parts of butanediol; 263-8 parts of glycerol polyether; 3-7 parts of isononyl isononanoate; 3-5 parts of behenyl alcohol; 2-2.5 parts of polydimethylsiloxane; 1-2 parts of betaine; 0.5-1 part of octyl polymethylsiloxane; 0.5-1 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.5 to 0.8 portion of cetearyl alcohol; coco glucoside 0.1-0.2 parts; 0.2-0.4 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.1 to 0.2 portion of isohexadecane; polysorbate-800.05-0.06 parts; 0.1-0.2 parts of carbomer; 0.1 to 0.3 portion of p-hydroxyacetophenone; 0.1 to 0.2 portion of pH regulator; 0.21-0.52 part of preservative; 0.01-0.05 part of chelating agent; 0.015 to 0.03 portion of aromatic; 3.3022 parts to 6.409 parts of a skin conditioner; 55-80 parts of water;
wherein the skin conditioner is prepared from the following components in a mass ratio of 2-3: 0.1-0.5: 0.3-0.6: 0.2-0.5: 0.402-0.908: 0.1002-0.501: 0.1-0.2: 0.1-0.2 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, a second complexing agent, oligopeptide-1, and carnosine.
The invention combines various skin conditioners which are beneficial to skin absorption and improve the skin state with water, butanediol, isononyl isononanoate, pH regulator and other components, so that the skin conditioner is easier to skin absorption, moistens the skin, reduces water loss, improves skin wrinkles, strengthens skin elasticity, makes the appearance ruddy, accelerates nutrition absorption and improves the skin state.
Further, the first complexing agent consists of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid and ascorbyl palmitate with the mass ratio of 0.2-0.4:0.1-0.3:0.1-0.2: 0.002-0.008. The hydroxyphenyl propionamide benzoic acid can effectively inhibit skin erythema, edema and pruritus caused by histamine, the ascorbyl palmitate has all physiological activities of vitamin C, can play a role in resisting inflammation, reducing melanin generation, promoting immunoglobulin synthesis, preventing and treating pigmentation caused by trauma, sunburn, acne and the like, can whiten skin, maintain skin elasticity, relieve wrinkles, improve the phenomena of rough skin, pale skin, relaxation and the like, and delay natural aging and photoaging of skin, and the absorption of the hydroxyphenyl propionamide benzoic acid and the ascorbyl palmitate can be accelerated by matching the hydroxyphenyl propionamide benzoic acid, the ascorbyl palmitate with 1, 2-pentanediol and butanediol.
Further, the second complexing agent consists of water, saccharide isomer, citric acid and sodium citrate in a mass ratio of 0.09-0.45:0.01-0.05:0.0001-0.0005: 0.0001-0.0005. The saccharide isomerate is a natural water-retaining agent and emollient extracted from natural plant saccharide complex, is similar to carbohydrate complex in human body, has good skin-friendly performance, and helps water combine with keratin of horny layer to achieve moisturizing effect.
Further, the saccharide isomer consists of d-glucose, l-glucose, d-fructose, d-mannose and d-idose. Preferably, the mass ratio of the d-glucose, the l-glucose, the d-fructose, the d-mannose and the d-idose is 1:3:1:2: 1-3.
Further, the saccharide isomers consist of arabinose and ribose. Preferably, the mass ratio of arabinose to ribose is 1: 1-3.
Further, the saccharide isomer consists of deoxyribose and rhamnose. Preferably, the mass ratio of deoxyribose to rhamnose is 2: 1.
Further, the saccharide isomerate is composed of psicose, aroinose, and maltose. Preferably, the mass ratio of the psicose, the aureone and the maltose is 1:1: 2.
Further, the pH regulator is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use.
Further, the preservative consists of caprylyl hydroximic acid, 1, 2-hexanediol and 1, 3-propanediol in a mass ratio of 0.01-0.02:0.1-0.2: 0.1-0.3. Through the compounding of multiple preservatives to reduce the use amount of single preservative, simultaneously, each preservative has the bactericidal degerming effect, can strengthen the bactericidal degerming effect of product.
Preferably, the mass ratio of the skin conditioner to the pH regulator to the water is 1: 0.03: 12-16.
The invention also provides a preparation method of the moisturizing composition, which comprises the following preparation steps:
s1: formulating the components of the moisturizing composition of claim 1;
s2: sequentially adding water, butanediol, glyceryl polyether-26, betaine, nicotinamide, carbomer, p-hydroxyacetophenone and chelating agent into a water phase pot, stirring at the speed of 20r/min-30r/min, heating to 80-85 ℃, and dissolving or dispersing completely to form a mixture A;
s3: sequentially adding isononyl isononanoate, behenyl alcohol, polydimethylsiloxane, octyl methicone and PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer into an oil phase pot, stirring at the speed of 20r/min-30r/min, heating to 75-80 ℃, and dissolving completely to form a mixture B;
s4: pumping the mixture A into an emulsifying pot, pumping the mixture A completely, then pumping the mixture B into the emulsifying pot under stirring at the speed of 20r/min-30r/min, homogenizing under vacuum for 5min-10min, then keeping the temperature and stirring for 20min-40min, then beginning to cool, cooling to 50 ℃ -55 ℃, then sequentially adding sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80 and pH regulator, stirring uniformly at the speed of 15r/min-25r/min, then cooling to 40 ℃ -45 ℃, sequentially adding glycosaminoglycans, hydrolyzed collagen, sarcandra glabra extract, first complexing agent, second complexing agent, oligopeptide-1, carnosine, preservative and aromatic, stirring uniformly at the speed of 10r/min-20r/min, cooling to below 40 deg.C, stirring, inspecting, and filtering.
Compared with the prior art, the invention has the beneficial effects that:
the invention combines a plurality of skin conditioners which are beneficial to skin absorption and improve the skin state with water, butanediol, isononyl isononanoate, pH regulator and other components, so that the skin conditioner is easier to skin absorption, moistens the skin, reduces water loss, improves skin wrinkles, strengthens the skin elasticity, makes the appearance ruddy, accelerates the absorption of nutrition and improves the skin state.
In the invention, the concentration of the nicotinamide is below 2%, the absorption rate is increased along with the increase of the addition amount, and the absorption rate is not increased when the concentration exceeds 2%, although the addition concentration of the nicotinamide is high, the effect is better, but the irritation is also greatly increased, so that the skin conditioner can be promoted to be absorbed by the skin by matching with other skin conditioners according to the appropriate addition amount of the nicotinamide.
Detailed Description
The present invention is further described below with reference to specific embodiments, and it should be noted that, without conflict, any combination between the embodiments or technical features described below may form a new embodiment.
The product of the invention is off-white and cream-like in color, and the pH range is 5.5-7.5. The product of the invention should be stored in a ventilated drying warehouse with the temperature not higher than 38 ℃, and not close to a water source, a stove or a heater, the distance between the product and the ground is at least 20cm during storage, a channel is reserved in the middle of the product and 50cm away from the inner wall, the product is stacked according to box graphic signs, and the first-in first-out principle is strictly controlled.
The following are specific examples of the present invention, and raw materials, equipment, and the like used in the following examples can be obtained by purchasing, unless otherwise specified. In the following embodiments, the water is pure water or deionized water, unless otherwise specified.
Example 1
The light cream comprises the following components in parts by weight:
4 parts of butanediol; glycerol polyether-263 parts; 3 parts of isononyl isononanoate; 3 parts of behenyl alcohol; 2 parts of polydimethylsiloxane; 1 part of betaine; 0.5 part of octyl polymethylsiloxane; 0.5 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.5 part of cetearyl alcohol; coco glucoside 0.1 parts; 0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.1 part of isohexadecane; polysorbate-800.05 parts; 0.1 part of carbomer; 0.1 part of p-hydroxyacetophenone; 0.1 part of pH regulator; 0.21 part of preservative; 0.01 part of chelating agent; 0.015 part of aromatic; 3.3022 parts of a skin conditioner; 55 parts of water;
wherein the pH regulator is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use; the skin conditioner is prepared from the following components in a mass ratio of 2:0.1: 0.3:0.2: 0.402: 0.1002: 0.1:0.1 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, a second complexing agent, oligopeptide-1 and carnosine. The first complexing agent consists of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid and ascorbyl palmitate with the mass ratio of 0.2:0.1:0.1: 0.002. The second complexing agent consists of water, saccharide isomerate, citric acid and sodium citrate with the mass ratio of 0.09:0.01:0.0001: 0.0001. The saccharide isomerate comprises d-glucose, l-glucose, d-fructose, d-mannose and d-idose in a mass ratio of 1:3:1:2: 2.
The preparation method of the light cream comprises the following preparation steps:
s1: formulating the components of the moisturizing composition of claim 1;
s2: sequentially adding water, butanediol, glyceryl polyether-26, betaine, nicotinamide, carbomer, p-hydroxyacetophenone and chelating agent into a water phase pot, stirring at the speed of 20r/min-30r/min, heating to 80-85 ℃, and dissolving or dispersing completely to form a mixture A;
s3: sequentially adding isononyl isononanoate, behenyl alcohol, polydimethylsiloxane, octyl methicone and PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer into an oil phase pot, stirring at the speed of 20r/min-30r/min, heating to 75-80 ℃, and dissolving completely to form a mixture B;
s4: pumping the mixture A into an emulsifying pot, pumping the mixture A completely, then pumping the mixture B into the emulsifying pot under stirring at the speed of 20r/min-30r/min, homogenizing under vacuum for 5min-10min, then keeping the temperature and stirring for 20min-40min, then beginning to cool, cooling to 50 ℃ -55 ℃, then sequentially adding sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80 and pH regulator, stirring uniformly at the speed of 15r/min-25r/min, then cooling to 40 ℃ -45 ℃, sequentially adding glycosaminoglycans, hydrolyzed collagen, sarcandra glabra extract, first complexing agent, second complexing agent, oligopeptide-1, carnosine, preservative and aromatic, stirring uniformly at the speed of 10r/min-20r/min, cooling to below 40 deg.C, stirring, inspecting, and filtering.
Example 2
Unlike example 1, the light cream of example 2 includes the following components in parts by weight:
6 parts of butanediol; 265.5 parts of glycerol polyether; 5 parts of isononyl isononanoate; 4 parts of behenyl alcohol; 2.25 parts of polydimethylsiloxane; 1.5 parts of betaine; octyl polymethylsiloxane 0.75 parts; 0.75 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.65 part of cetearyl alcohol; coco glucoside 0.15 parts; 0.3 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.15 part of isohexadecane; polysorbate-800.055 parts; 0.15 part of carbomer; 0.2 part of p-hydroxyacetophenone; 0.15 part of pH regulator; 0.365 part of preservative; 0.03 part of chelating agent; 0.03 part of aromatic; 4.8556 parts of a skin conditioner; 67 parts of water;
wherein the pH regulator is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use; the skin conditioner is prepared from the following components in a mass ratio of 2.5: 0.3: 0.46: 0.35: 0.655: 0.3006: 0.15: 0.15 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, a second complexing agent, oligopeptide-1, and carnosine. The first complexing agent consists of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid and ascorbyl palmitate with the mass ratio of 0.3:0.2:0.15: 0.005. The second complexing agent consists of water, saccharide isomerate, citric acid and sodium citrate in a mass ratio of 0.27:0.03:0.0003: 0.0003. The saccharide isomerate comprises d-glucose, l-glucose, d-fructose, d-mannose and d-idose in a mass ratio of 1:3:1:2: 2.
Other components and preparation methods are the same as those in example 1, and are not described again.
Example 3
Unlike example 1, the light cream of example 3 includes the following components in parts by weight:
8 parts of butanediol; glycerol polyether-268 parts; 7 parts of isononyl isononanoate; 5 parts of behenyl alcohol; 2.5 parts of polydimethylsiloxane; 2 parts of betaine; 1 part of octyl polymethylsiloxane; 1 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.8 part of cetearyl alcohol; coco glucoside 0.2 parts; 0.4 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.2 part of isohexadecane; polysorbate-800.06 parts; 0.2 part of carbomer; 0.3 part of p-hydroxyacetophenone; 0.2 part of pH regulator; 0.52 part of preservative; 0.05 part of a chelating agent; 0.03 part of aromatic; 6.409 parts of a skin conditioner; 80 parts of water;
wherein the pH regulator is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use; the skin conditioner is prepared from the following components in a mass ratio of 3: 0.5: 0.6: 0.5: 0.908: 0.501: 0.2: 0.2 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, a second complexing agent, oligopeptide-1 and carnosine. The first complexing agent consists of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid and ascorbyl palmitate with the mass ratio of 0.4:0.3:0.2: 0.008. The second complexing agent consists of water, saccharide isomerate, citric acid and sodium citrate in a mass ratio of 0.45:0.05:0.0005: 0.0005. The saccharide isomerate comprises d-glucose, l-glucose, d-fructose, d-mannose and d-idose in a mass ratio of 1:3:1:2: 2.
Other components and preparation methods are the same as those in example 1, and are not described again.
Example 4
Unlike example 1, the saccharide isomer in the light cream of example 4 consists of arabinose and ribose in a mass ratio of 1: 2.
Other components and preparation methods are the same as those in example 1, and are not described again.
Example 5
Unlike example 1, the saccharide isomer in the light cream of example 5 consists of deoxyribose to rhamnose in a mass ratio of 2: 1.
Other components and preparation methods are the same as those in example 1, and are not described again.
In the above embodiments, each material is not limited to the above components, and each material may also be composed of other single components or multiple components described in the present invention, and the component parts of each material are not limited to the above parts, and the component parts of each material may also be a combination of other component parts described in the present invention, and are not described herein again.
Comparative example 1
Comparative example 1 is a light cream, which is different from example 1 in that the first complexing agent is not used in the raw material of comparative example 1, i.e., the light cream of comparative example 1 comprises the following components in parts by weight:
4 parts of butanediol; glycerol polyether-263 parts; 3 parts of isononyl isononanoate; 3 parts of behenyl alcohol; 2 parts of polydimethylsiloxane; 1 part of betaine; 0.5 part of octyl polymethylsiloxane; 0.5 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.5 part of cetearyl alcohol; coco glucoside 0.1 parts; 0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.1 part of isohexadecane; polysorbate-800.05 parts; 0.1 part of carbomer; 0.1 part of p-hydroxyacetophenone; 0.1 part of pH regulator; 0.21 part of preservative; 0.01 part of chelating agent; 0.015 part of aromatic; 2.9002 parts of a skin conditioner; 55 parts of water;
wherein the pH regulator is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use; the skin conditioner is prepared from the following components in a mass ratio of 2:0.1: 0.3:0.2: 0.1002: 0.1:0.1 part of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a second complexing agent, oligopeptide-1, and carnosine. The second complexing agent consists of water, saccharide isomerate, citric acid and sodium citrate with the mass ratio of 0.09:0.01:0.0001: 0.0001. The saccharide isomerate comprises d-glucose, l-glucose, d-fructose, d-mannose and d-idose in a mass ratio of 1:3:1:2: 2.
Other components and preparation methods are the same as those in example 1, and are not described again.
Comparative example 2
Comparative example 2 is a light cream, which is different from example 1 in that the second complexing agent is not used in the raw material of comparative example 2, i.e., the light cream of comparative example 2 comprises the following components in parts by weight:
4 parts of butanediol; glycerol polyether-263 parts; 3 parts of isononyl isononanoate; 3 parts of behenyl alcohol; 2 parts of polydimethylsiloxane; 1 part of betaine; 0.5 part of octyl polymethylsiloxane; 0.5 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.5 part of cetearyl alcohol; coco glucoside 0.1 parts; 0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.1 part of isohexadecane; polysorbate-800.05 parts; 0.1 part of carbomer; 0.1 part of p-hydroxyacetophenone; 0.1 part of pH regulator; 0.21 part of preservative; 0.01 part of chelating agent; 0.015 part of aromatic; 3.202 parts of a skin conditioner; 55 parts of water;
wherein the pH regulator is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use; the skin conditioner is prepared from the following components in a mass ratio of 2:0.1: 0.3:0.2: 0.402: 0.1:0.1 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, oligopeptide-1 and carnosine. The first complexing agent consists of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid and ascorbyl palmitate with the mass ratio of 0.2:0.1:0.1: 0.002.
Other components and preparation methods are the same as those in example 1, and are not described again.
Comparative example 3
Comparative example 3 is a light cream, which is different from example 1 in that no pH adjuster is used in the raw material of comparative example 3, i.e., the light cream of comparative example 3 includes the following components in parts by weight:
4 parts of butanediol; glycerol polyether-263 parts; 3 parts of isononyl isononanoate; 3 parts of behenyl alcohol; 2 parts of polydimethylsiloxane; 1 part of betaine; 0.5 part of octyl polymethylsiloxane; 0.5 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.5 part of cetearyl alcohol; coco glucoside 0.1 parts; 0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.1 part of isohexadecane; polysorbate-800.05 parts; 0.1 part of carbomer; 0.1 part of p-hydroxyacetophenone; 0.21 part of preservative; 0.01 part of chelating agent; 0.015 part of aromatic; 3.3022 parts of a skin conditioner; 55 parts of water;
wherein the chelating agent is disodium EDTA; the aromatic is essence for daily use; the skin conditioner is prepared from the following components in a mass ratio of 2:0.1: 0.3:0.2: 0.402: 0.1002: 0.1:0.1 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, a second complexing agent, oligopeptide-1 and carnosine. The first complexing agent consists of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid and ascorbyl palmitate with the mass ratio of 0.2:0.1:0.1: 0.002. The second complexing agent consists of water, saccharide isomerate, citric acid and sodium citrate with the mass ratio of 0.09:0.01:0.0001: 0.0001. The saccharide isomerate comprises d-glucose, l-glucose, d-fructose, d-mannose and d-idose in a mass ratio of 1:3:1:2: 2.
And (3) performance detection:
first, Mild Effect determination
1. The experimental method comprises the following steps: each example selected 30 eligible subjects for testing.
Adopting skin closed patch test, selecting patch with area not more than 50mm2And qualified spot test equipment with the depth of about 1 mm.
Placing the experimental product into a spot tester chamber, wherein the dosage is about 0.020mL-0.025mL, applying the spot tester with the tested object to the curved side of the forearm of the tested object by using hypoallergenic adhesive tape, slightly pressing the spot tester with the palm to uniformly apply the spot tester to the skin for 24 hours, and observing the skin reaction for 24 hours according to the skin reaction grading standard of the skin-closed spot test.
2. Subject: the light creams prepared in examples 1-5 and comparative examples 1-3.
3. The results of the tests, are given in table 1 below:
TABLE 1
Note: + represents no adverse reaction; + represents that a small amount of irritation can be felt but no adverse reaction occurs; the + and + indicates that strong stimulation can be felt, but no adverse reaction occurs; the sign of +++ indicates that strong irritation is felt and adverse reaction occurs.
As can be seen from Table 1, the light cream provided by the invention is mild, safe, non-irritating to the skin and reliable in use.
Second, test experiment for wrinkle, compactness and elasticity of skin
1. Test objects: according to the ratio of 1:1 of male and female, selecting volunteers with age of 30-50 years, having no skin disease history, and dividing into 20 persons/group, wherein one group is used as a control group and does not use any product; 5 groups of the moisturizing compositions obtained in the above examples were used; 3 groups of the 3 light creams of comparative examples 1 to 3 were used, respectively; of the 20 people in each group, those who contained as few fine wrinkles as possible, deep wrinkles; and (5) testing each tester initial texture, skin compactness, elasticity and other indexes at the beginning of the test, and recording the initial values.
2. A detection instrument: the model of the Bo-Shi electronic automatic analysis skin detection system is as follows: and (4) CBS.
3. The detection principle is as follows: a skin image processing system digitally processes using a probe mirror technique to visualize the underlying pigment and skin health and to measure and monitor these changes over time.
4. Test time: for 6 weeks.
5. Testing parts: canthus, forehead, mouth corner.
6. Test mode and requirements: after the skin is cleaned, a proper amount of the product is uniformly smeared on the surface of the skin, and is gently massaged and absorbed, so that the skin-care product is used in the morning and evening and is continuously used for a period of time. After 6 weeks, each subject was examined using the instrument and the number of people who improved wrinkles, elasticity and skin firmness by more than 30% was recorded.
7. And (3) testing results: as in table 2 below.
TABLE 2
As can be seen from table 2 above, the light cream provided by the present invention has a significant effect on skin, i.e., can regulate the loss of transdermal moisture, and reduce the activity of sebaceous glands, thereby fundamentally preventing the problem of skin aging.
The above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention is not limited thereby, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention are within the protection scope of the present invention.
Claims (10)
1. The moisturizing composition is characterized by comprising the following components in parts by weight:
4-8 parts of butanediol; 263-8 parts of glycerol polyether; 3-7 parts of isononyl isononanoate; 3-5 parts of behenyl alcohol; 2-2.5 parts of polydimethylsiloxane; 1-2 parts of betaine; 0.5-1 part of octyl polymethylsiloxane; 0.5-1 part of PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer; 0.5 to 0.8 portion of cetearyl alcohol; coco glucoside 0.1-0.2 parts; 0.2-0.4 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer; 0.1 to 0.2 portion of isohexadecane; polysorbate-800.05-0.06 parts; 0.1-0.2 parts of carbomer; 0.1 to 0.3 portion of p-hydroxyacetophenone; 0.1 to 0.2 portion of pH regulator; 0.21-0.52 part of preservative; 0.01-0.05 part of chelating agent; 0.015 to 0.03 portion of aromatic; 3.3022 parts to 6.409 parts of a skin conditioner; 55-80 parts of water;
wherein the skin conditioner is prepared from the following components in a mass ratio of 2-3: 0.1-0.5: 0.3-0.6: 0.2-0.5: 0.402-0.908: 0.1002-0.501: 0.1-0.2: 0.1-0.2 of glycosaminoglycans, hydrolyzed collagen, sargassum biflorum extract, nicotinamide, a first complexing agent, a second complexing agent, oligopeptide-1, and carnosine.
2. The moisturizing composition of claim 1, wherein the first complexing agent is composed of 1, 2-pentanediol, butanediol, hydroxyphenylpropionamide benzoic acid, and ascorbyl palmitate in a mass ratio of 0.2-0.4:0.1-0.3:0.1-0.2: 0.002-0.008.
3. The moisturizing composition of claim 1, wherein the second complexing agent comprises water, saccharide isomers, citric acid, and sodium citrate in a mass ratio of 0.09 to 0.45:0.01 to 0.05:0.0001 to 0.0005.
4. The moisturizing composition of claim 3, wherein said saccharide isomers consist of d-glucose, l-glucose, d-fructose, d-mannose, d-idose.
5. The moisturizing composition of claim 3, wherein the saccharide isomers consist of arabinose and ribose.
6. The moisturizing composition of claim 3, wherein the saccharide isomers consist of deoxyribose and rhamnose.
7. The moisturizing composition of claim 3, wherein said saccharide isomers consist of deoxyribose and rhamnose.
8. The moisturizing composition of claim 1, wherein the pH adjusting agent is triethanolamine; the chelating agent is EDTA disodium; the aromatic is essence for daily use.
9. The moisturizing composition of claim 1, wherein the preservative consists of caprylhydroxamic acid, 1, 2-hexanediol, and 1, 3-propanediol in a mass ratio of 0.01-0.02:0.1-0.2: 0.1-0.3.
10. A method for preparing a moisturizing composition, comprising the steps of:
s1: formulating the components of the moisturizing composition of claim 1;
s2: sequentially adding water, butanediol, glyceryl polyether-26, betaine, nicotinamide, carbomer, p-hydroxyacetophenone and chelating agent into a water phase pot, stirring at the speed of 20r/min-30r/min, heating to 80-85 ℃, and dissolving or dispersing completely to form a mixture A;
s3: sequentially adding isononyl isononanoate, behenyl alcohol, polydimethylsiloxane, octyl methicone and PEG-12 polydimethylsiloxane/PPG-20 cross-linked polymer into an oil phase pot, stirring at the speed of 20r/min-30r/min, heating to 75-80 ℃, and dissolving completely to form a mixture B;
s4: pumping the mixture A into an emulsifying pot, pumping the mixture A completely, then pumping the mixture B into the emulsifying pot under stirring at the speed of 20r/min-30r/min, homogenizing under vacuum for 5min-10min, then keeping the temperature and stirring for 20min-40min, then beginning to cool, cooling to 50 ℃ -55 ℃, then sequentially adding sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80 and pH regulator, stirring uniformly at the speed of 15r/min-25r/min, then cooling to 40 ℃ -45 ℃, sequentially adding glycosaminoglycans, hydrolyzed collagen, sarcandra glabra extract, first complexing agent, second complexing agent, oligopeptide-1, carnosine, preservative and aromatic, stirring uniformly at the speed of 10r/min-20r/min, cooling to below 40 deg.C, stirring, inspecting, and filtering.
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Cited By (2)
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CN113908073A (en) * | 2021-11-18 | 2022-01-11 | 广州梵之容化妆品有限公司 | Whitening lotion and preparation method thereof |
CN115444772A (en) * | 2022-10-26 | 2022-12-09 | 广州艾卓生物科技股份有限公司 | Moisturizing and whitening composition and application thereof in radio frequency beauty treatment and medical beauty skin care |
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2020
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113908073A (en) * | 2021-11-18 | 2022-01-11 | 广州梵之容化妆品有限公司 | Whitening lotion and preparation method thereof |
CN115444772A (en) * | 2022-10-26 | 2022-12-09 | 广州艾卓生物科技股份有限公司 | Moisturizing and whitening composition and application thereof in radio frequency beauty treatment and medical beauty skin care |
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