CN115429738A

CN115429738A - Acne-removing repairing revitalizing essence and preparation method thereof

Info

Publication number: CN115429738A
Application number: CN202211328740.9A
Authority: CN
Inventors: 杨慧
Original assignee: Hangzhou Shujian Cosmetics Co ltd
Current assignee: Hangzhou Shujian Cosmetics Co ltd
Priority date: 2022-10-26
Filing date: 2022-10-26
Publication date: 2022-12-06
Anticipated expiration: 2042-10-26
Also published as: CN115429738B

Abstract

The application provides acne-removing repairing revitalizing essence and a preparation method thereof, and relates to the technical field of skin care products. The acne-removing repairing rejuvenating essence comprises the following raw materials in percentage by weight: disodium ethylene diamine tetraacetate, glycerol, butanediol, 1, 3-propylene glycol, carbomer, xanthan gum, p-hydroxyacetophenone, rhamnose, arginine, mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, bletilla striata extract, white willow bark extract, methyl gluceth-20, 1, 2-pentanediol, glycerol glucoside, inositol, royal jelly extract and the balance of water. According to the application, discomfort of the product is reduced while the acne removing effect is improved, the use comfort level is improved, the white willow extract is used for replacing the irritating sensation brought by the traditional salicylic acid, the pure plant extract compound components have multiple acne resisting effects (bacteriostasis, oil control, keratosis resistance and inflammation relief), the skin is treated by adopting a traditional Chinese medicine idea, and the acne root cause is directly attacked.

Description

Acne-removing repairing and revitalizing essence and preparation method thereof

Technical Field

The application relates to the technical field of skin care products, and particularly relates to an acne-removing repairing revitalizing essence and a preparation method thereof.

Background

Acne is also called whelk, and is closely related to factors such as excessive sebum secretion, blockage of pilosebaceous canal, bacterial infection, inflammatory reaction and the like. After adolescence, the level of androgen, particularly testosterone, in a human body is rapidly increased, the development of sebaceous glands is promoted, and a large amount of sebum is produced. Meanwhile, abnormal keratinization of the pilosebaceous canal causes the canal to be blocked, sebum is obstructed to be discharged, and a keratoplug, namely micro acne, is formed. Lipases produced by various microorganisms in the hair follicle break down sebum to produce free fatty acids, while chemotactic inflammatory cells and mediators, ultimately inducing and exacerbating the inflammatory response. Acne lesions occur well on the face and upper chest and back and are manifested as comedo, inflammatory papule, secondary pustule, nodule and other lesions, often accompanied by seborrhea. The traditional Chinese medicine preparation is easy to form the remaining diseases such as pigmentation, large pores and even scars, and has serious influence on the psychology and life of patients.

At present, acne is clinically treated mainly by medicines surrounding pathogenesis, and (1) anti-androgen medicines are commonly used, which mainly reduce facial sebum secretion by inhibiting synthesis of in vivo androgen; (2) anti-follicular duct parakeratosis drugs, such as tretinoin drugs; (3) anti-acne bacteria drugs, such as benzoyl peroxide, erythromycin, clindamycin, tetracycline, etc. Although the treatment of western medicine in a short period can achieve certain curative effect, the treatment has a larger problem. For example, the use of antiandrogens may cause endocrine disorders in themselves; the use of the quick-sterilizing acne-removing medicine can cause the phenomena of dry skin, peeling, erythema, large pores and the like. These results show that the current clinical acne treatment drugs have limited curative effect, and a safe and effective treatment means is not available, so that many acne patients need long-term repeated treatment, but finally obvious marks are formed, and the appearance and confidence of the patients are seriously influenced.

Therefore, the acne-removing repairing essence is a daily-used acne-removing repairing essence, and the effect that a user can safely and fundamentally solve acne in the using and conditioning period is guaranteed.

Disclosure of Invention

The application aims to provide the acne-removing repairing revitalizing essence which has the advantages of mildly repairing, brightening, whitening and moistening skin and treating acne.

Another objective of the present application is to provide a preparation method of the acne-removing rejuvenating essence, so as to obtain the acne-removing rejuvenating essence.

The technical problem to be solved by the application is solved by adopting the following technical scheme.

On one hand, the embodiment of the application provides an acne-removing repairing revitalizing essence which comprises the following raw materials in percentage by weight: 0.01-0.05% of disodium ethylene diamine tetraacetate, 1-4% of glycerol, 1-3% of butanediol, 1.4-3.64% of 1, 3-propylene glycol, 0.1-0.5% of carbomer, 0.05-0.15% of xanthan gum, 0.1-0.5% of p-hydroxyacetophenone, 0.1-0.5% of rhamnose, 0.2-0.6% of arginine, 2-5% of mixed extract, 0.1-0.5% of panthenol, 0.01-0.07% of caprylyl hydroximic acid, 0.1-0.34% of 1, 2-hexanediol, 1-7% of bletilla striata extract, 0.2-0.8% of willow bark extract, 201-3% of methyl gluceth, 0.15-0.4% of 1, 2-0.4% of pentanediol, 0.15-0.4% of glycerol glucoside, 0.1-0.3% of inositol, 0.2-0.8% of royal jelly extract and the balance of water.

On the other hand, the embodiment of the application provides a preparation method of the acne-removing rejuvenation essence, which comprises the following steps:

slowly scattering carbomer into a preparation pot containing water and disodium ethylene diamine tetraacetate for soaking, stirring and heating for dissolving after completely wetting;

pre-dispersing 1, 3-propylene glycol and xanthan gum, adding into a preparation pot, stirring until the mixture is dissolved, sequentially adding glycerol, butanediol and p-hydroxyacetophenone into the preparation pot, stirring until the mixture is completely dissolved, and then stirring and cooling;

after the temperature of the preparation pot is reduced, adding rhamnose and arginine into the preparation pot, vacuumizing and stirring uniformly;

after the temperature of the preparation pot is reduced, the mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, bletilla striata extract, white willow bark extract, methyl glucitol polyether-20, 1, 2-pentanediol, glycerol glucoside, inositol and royal jelly extract are sequentially added into the preparation pot, the vacuum is continuously kept, and the stirring is uniform, so that the acne-removing repairing revitalizing essence is obtained.

Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:

the application reduces the discomfort of the product while increasing the acne removing effect, improves the use comfort level, replaces the irritation brought by the traditional salicylic acid with the white willow extract, extracts the compound components from pure plants, has multiple anti-acne effects (bacteriostasis, oil control, keratinization resistance and inflammation relief), treats the skin with the skin by adopting the traditional Chinese medicine concept, and directly attacks the root cause of the acne.

Specifically, the inventor uses glycerol, butanediol, 1, 3-propylene glycol, methyl glucitol polyether-20, 1, 2-hexanediol and 1, 2-pentanediol as a humectant and a solvent, so that the skin can be comfortably used, and the molecule of glycerol contains three-OH groups which form hydrogen bonds with water molecules, so that water is bound, and a good moisture absorption and retention effect is achieved. The skin and hair of a human body are obviously moistened, the moisture can be supplemented to the horny layer of the skin, the physiological action of the skin is adjusted, the health of the skin is kept, and the use feeling is improved; butanediol is a polyalcohol with mild texture, can increase the smoothness of essence, and is a micromolecular moisturizing component; the 1, 3-propylene glycol has strong active permeability, can make the skin smooth, promotes the absorption of subsequent skin care products, and has excellent moisturizing effect; the 1, 2-hexanediol has the effects of sterilization and moisture retention; 1, 2-pentanediol has excellent moisturizing properties of glycols, and in addition, has antibacterial and solubilizing effects. And disodium ethylene diamine tetraacetate and caprylyl hydroximic acid are used as chelating agents, have a stabilizing effect in cosmetics, have a certain synergistic effect on a preservative system and an antioxidant system, and are beneficial to prolonging the quality guarantee period of the essence. Carbomer and xanthan gum are used as the thickening agent, so that the essence has more comfortable use experience. The p-hydroxyacetophenone is used as the preservative, is effective to fungi, has strong killing capacity to aspergillus niger, has a certain inhibiting effect to pseudomonas aeruginosa, has excellent stability in high and low pH and temperature ranges, can prolong the quality guarantee period of active ingredients of other substances under a high temperature condition, can promote the efficacy of various substances, and has good compatibility with various ingredients. Rhamnose can promote the structure of hemidesmosome, which is mainly located on the bottom surface of epithelial cell and is used for connecting epithelial cell with basement membrane below the epithelial cell, so that rhamnose can enhance the barrier function of skin, promote proliferation of stratum corneum cell, activate skin and resist wrinkle, and increase cortex humidity. Arginine can cooperate with other moisture-keeping components to keep the moisture of the skin and soften the skin. The mixed extract can effectively play the composite effects of maintaining skin, removing acne and diminishing inflammation. The panthenol molecule can penetrate into skin stratum corneum and hair, and quickly reduce to vitamin B5 under the action of enzyme, so as to keep skin tender. The bletilla striata extract has good antioxidant, skin whitening and anti-inflammatory effects, can promote the healing of sore surfaces, has severe acne skin inflammation, can promote the recovery of inflammatory parts, has a remarkable inhibiting effect on human tubercle bacillus, has an inhibiting effect on candida albicans and trichophyton, and can prevent bacteria from aggravating the conditions of affected parts. The main active ingredient of the white willow bark extract is salicin, the salicin is an anti-inflammatory agent prepared from the willow bark, and the salicin can promote wound healing, calm joints and relieve muscle pain after being metabolized into salicylic acid by a human body. The glycerol glucoside can protect cells from being damaged by severe environments such as high osmotic pressure, high temperature, drought and ultraviolet rays, has the effects of resisting oxidation and aging, repairing skin and the like, and can effectively activate cells and promote cell regeneration; enhancing the vitality of cells and accelerating the process of cell metabolism; stimulating skin cells to regrow; enhancing the antioxidant capacity (SOD) of epidermal skin cells; accelerating the synthesis of type I collagen precursors in aging cells. Inositol has the same functions as biotin and vitamin B, has the functions of nourishing, moisturizing and conditioning the skin, and can increase the luster of the skin; the moisturizing capability of the product is equal to that of glycerin, and the product does not generate sticky feeling with glycerin when used at high concentration. Inositol has good transdermal permeability, and can promote the permeation of other components. The royal jelly extract contains protein, lipid, saccharides, other vitamins, amino acids and mineral substances, contains abundant superoxide dismutase, transaminase, cholinesterase, antibacterial peptide and various royal jelly main proteins, is an important basis for the aging resistance, the tumor resistance, the antibiosis, the immunity regulation and the cell proliferation promotion of royal jelly, contains more than 20 amino acids, can endow cell energy, recover the cell activity, help the skin growth and has a certain treatment effect on seborrheic dermatitis and acne. Under the action of various raw materials, the acne-removing face cream can treat skin acne and simultaneously stably repair skin on the basis of keeping moisture and stabilizing skin, and has outstanding effects of maintaining stability, repairing and maintaining skin.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to specific examples.

The embodiment of the application provides acne-removing repairing revitalizing essence which comprises the following raw materials in percentage by weight: 0.01-0.05% of disodium ethylene diamine tetraacetate, 1-4% of glycerol, 1-3% of butanediol, 1.4-3.64% of 1, 3-propylene glycol, 0.1-0.5% of carbomer, 0.05-0.15% of xanthan gum, 0.1-0.5% of p-hydroxyacetophenone, 0.1-0.5% of rhamnose, 0.2-0.6% of arginine, 2-5% of mixed extract, 0.1-0.5% of panthenol, 0.01-0.07% of caprylyl hydroximic acid, 0.1-0.34% of 1, 2-hexanediol, 1-7% of bletilla striata extract, 0.2-0.8% of willow bark extract, 201-3% of methyl gluceth, 0.15-0.4% of 1, 2-0.4% of pentanediol, 0.15-0.4% of glycerol glucoside, 0.1-0.3% of inositol, 0.2-0.8% of royal jelly extract and the balance of water.

In some embodiments of the present application, the above-mentioned mixed extract includes pomegranate rind extract, mangosteen rind extract, magnolia bark extract, red pine leaf extract, orange fruit extract, artemisia annua extract, water, glycerin, polysorbate-20, and dipropylene glycol.

The pomegranate peel extract has good lipid peroxidation resistance, can play a role in delaying senescence, has inhibition effect on xanthine oxidase, shows that the pomegranate peel extract has anti-inflammatory and astringent effects, and shows strong inhibition effect on the activity of B-16 melanocyte.

The inhibition effect of the garcinia mangostana pericarp extract on the collagen activity shows that the garcinia mangostana pericarp extract can slow down the degradation of collagen fibers, can maintain the skin elasticity, and has good anti-aging effect by combining the anti-oxygen property of the garcinia mangostana pericarp extract; it has effects in inhibiting tyrosinase, and can be used as whitening agent; it has histamine inhibiting effect and can be used for resisting allergy; it can also be used as humectant and hair growth promoter.

The cortex Magnolia officinalis extract contains magnolol as effective component, which has remarkable antifungal effect, can be used as antibacterial agent, and can be used for treating acne in combination with its antiinflammatory effect; the Magnolia officinalis extract has antioxidant effect, can eliminate free radicals, and has good antiaging effect.

The red pine leaf extract has an inhibiting effect on metalloprotease and has a good anti-inflammatory effect; has the effects of inhibiting the generation of NO, and resisting aging by combining the anti-oxygen property.

The Citrus junos extract has good cell proliferation activity, and can be used for preventing and treating red blood streak and caring dry skin.

Artemisia annua extract: has antibacterial, antiviral, antiinflammatory, analgesic, and skin condition stabilizing effects.

In some embodiments of the present application, the pomegranate rind extract, mangnolia officinalis bark extract, red pine leaf extract, orange fruit extract, artemisia annua extract, water, glycerin, polysorbate-20, and dipropylene glycol are present in a weight ratio of 5:2.5:2.5:0.1:0.1:0.1:270:800:70.

in some embodiments of the present application, the bletilla striata extract comprises a violet blue flower white and bulb extract, butylene glycol, p-hydroxyacetophenone, and 1, 2-hexanediol.

In some embodiments of the present application, the above acne-removing rejuvenating essence comprises the following raw materials by weight: 0.02-0.04% of disodium ethylene diamine tetraacetate, 2-3% of glycerol, 1.5-2.5% of butanediol, 2-3% of 1, 3-propylene glycol, 0.2-0.4% of carbomer, 0.08-0.12% of xanthan gum, 0.2-0.4% of p-hydroxyacetophenone, 0.2-0.4% of rhamnose, 0.3-0.5% of arginine, 2.5-5% of mixed extract, 0.3-0.4% of panthenol, 0.02-0.06% of caprylyl hydroximic acid, 0.2-0.3% of 1, 2-hexanediol, 2-6% of rhizoma bletillae extract, 0.3-0.7% of white willow bark extract, 201.5-3% of methyl glucitol polyether, 0.2-0.4% of 1, 2-0.4% of pentanediol, 0.2-0.3% of glycerol glucoside, 0.2-0.3% of inositol, 0.3-0.7% of royal jelly extract and the balance of water.

In some embodiments of the present application, the royal jelly extract comprises butylene glycol, decanediol, 10-hydroxydecanoic acid, and 1, 10-decanediol.

The embodiment of the application also provides a preparation method of the acne-removing repairing rejuvenating essence, which comprises the following steps:

after the preparation pot is cooled, sequentially adding the mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, bletilla striata extract, white willow bark extract, methyl glucitol polyether-20, 1, 2-pentanediol, glycerol glucoside, inositol and royal jelly extract into the preparation pot, continuously keeping vacuum, and uniformly stirring to obtain the acne-removing repairing and revitalizing essence.

In some embodiments of the present application, the carbomer is sprinkled into a dispensing pan containing water and disodium edetate and stirred at a frequency of 30-40Hz and heated to 82-88 deg.

In some embodiments of the present application, the 1, 3-propanediol and xanthan gum are pre-added to a preparation kettle and then stirred at a frequency of 25-35Hz until dissolved; the glycerol, the butanediol and the p-hydroxyacetophenone are sequentially added into a preparation pot and stirred at the frequency of 20-30Hz until the glycerol, the butanediol and the p-hydroxyacetophenone are completely dissolved.

In some embodiments of the present application, the rhamnose and arginine are added to the preparation kettle when the temperature of the preparation kettle is reduced to 45-55 ℃, the vacuum degree after vacuumizing is-0.04 Mpa, and the mixture is stirred to be uniform at the frequency of 20-30 Hz.

In some embodiments of the present application, the mixed extract, panthenol, caprylyl hydroxamic acid, 1, 2-hexanediol, bletilla striata extract, white willow bark extract, methyl gluceth-20, 1, 2-pentanediol, glycerol glucoside, inositol, and royal jelly extract are sequentially added to the preparation kettle as described above while the temperature of the preparation kettle is reduced to 35-45 ℃.

In some embodiments of the present application, the stirring frequency of the acne-removing rejuvenating essence is 15 to 25Hz.

The features and properties of the present application are described in further detail below with reference to examples.

Example 1

The preparation method of the acne-removing repairing rejuvenating essence comprises the following steps:

raw materials: disodium ethylenediaminetetraacetate 0.01%, glycerin 1%, butylene glycol 1%, 1, 3-propylene glycol 1.4%, carbomer 0.1%, xanthan gum 0.05%, p-hydroxyacetophenone 0.1%, rhamnose 0.1%, arginine 0.2%, mixed extracts 2%, panthenol 0.1%, caprylyl hydroxamic acid 0.01%, 1, 2-hexanediol 0.1%, bletilla striata extract 1%, willow bark extract 0.2%, methyl glucitol polyether-201%, 1, 2-pentanediol 0.15%, glycerol glucoside 0.15%, inositol 0.1%, royal jelly extract 0.2%, and the balance of water.

Slowly scattering carbomer into a preparation pot containing water and disodium ethylene diamine tetraacetate for soaking, stirring at the frequency of 30Hz and heating to 82 ℃ for dissolving after completely wetting;

pre-dispersing 1, 3-propylene glycol and xanthan gum, adding into a preparation pot, stirring at 25Hz frequency until the mixture is dissolved, sequentially adding glycerol, butanediol and p-hydroxyacetophenone into the preparation pot, stirring at 20Hz frequency until the mixture is completely dissolved, and then stirring and cooling;

cooling to 45 deg.C, adding rhamnose and arginine into the pot, vacuumizing to-0.04 Mpa, and stirring at 20 Hz;

cooling to 35 deg.C, sequentially adding the mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, rhizoma bletilla extract, white willow bark extract, methyl glucitol polyether-20, 1, 2-pentanediol, glycerol glucoside, inositol and Lac Regis Apis extract into the pot, continuously maintaining vacuum degree at-0.04 Mpa, and stirring at 15Hz frequency to obtain the essence for removing acne and revitalizing.

Example 2

A preparation method of an acne-removing repairing revitalizing essence comprises the following steps:

raw materials: disodium ethylene diamine tetraacetate 0.02%, glycerol 2%, butanediol 1.5%, 1, 3-propylene glycol 2%, carbomer 0.2%, xanthan gum 0.08%, p-hydroxyacetophenone 0.2%, rhamnose 0.2%, arginine 0.3%, mixed extract 2.5%, panthenol 0.3%, caprylyl hydroxamic acid 0.02%, 1, 2-hexanediol 0.2%, bletilla striata extract 2%, willow bark extract 0.3%, methyl gluceth-201.5%, 1, 2-pentanediol 0.2%, glycerol glucoside 0.2%, inositol 0.2%, royal jelly extract 0.3%, and the balance of water.

Slowly spreading carbomer in a pot containing water and disodium ethylene diamine tetraacetate, soaking, stirring at 30-40Hz, and heating to 82-88 deg.C for dissolving;

pre-dispersing 1, 3-propylene glycol and xanthan gum, adding into a preparation pot, stirring at 30Hz to dissolve, sequentially adding glycerol, butanediol and p-hydroxyacetophenone into the preparation pot, stirring at 25Hz to dissolve completely, and stirring to cool;

cooling to 50 deg.C, adding rhamnose and arginine into the pot, vacuumizing to-0.04 Mpa, and stirring at 25 Hz;

cooling to 35-45 deg.C, sequentially adding the mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, rhizoma Bletillae extract, white willow bark extract, methyl glucitol polyether-20, 1, 2-pentanediol, glycerol glucoside, inositol and Lac Regis Apis extract into the pot, keeping vacuum degree at-0.04 Mpa, and stirring at 20Hz to obtain the essence with anti-acne effect.

Example 3

This example is substantially the same as example 2, except that: raw materials: disodium ethylene diamine tetraacetate 0.03%, glycerol 2.5%, butanediol 2%, 1, 3-propanediol 2.5%, carbomer 0.3%, xanthan gum 0.1%, p-hydroxyacetophenone 0.3%, rhamnose 0.3%, arginine 0.5%, mixed extract 3.5%, panthenol 0.3.5%, caprylyl hydroxamic acid 0.04%, 1, 2-hexanediol 0.25%, bletilla striata extract 4%, willow bark extract 0.5%, methyl glucitol polyether-202.5%, 1, 2-pentanediol 0.3%, glycerol glucoside 0.25%, inositol 0.25%, royal jelly extract 0.5%, and the balance of water.

Example 4

This example is substantially the same as example 2, except that: raw materials: disodium ethylene diamine tetraacetate 0.04%, glycerol 3%, butanediol 2.5%, 1, 3-propylene glycol 3%, carbomer 0.4%, xanthan gum 0.12%, p-hydroxyacetophenone 0.4%, rhamnose 0.4%, arginine 0.5%, mixed extract 5%, panthenol 0.4%, caprylyl hydroxamic acid 0.06%, 1, 2-hexanediol 0.3%, bletilla striata extract 6%, willow bark extract 0.7%, methyl glucitol polyether-203%, 1, 2-pentanediol 0.4%, glycerol glucoside 0.3%, inositol 0.2-0.3%, royal jelly extract 0.7%, and the balance of water.

Example 5

raw materials: disodium ethylene diamine tetraacetate 0.05%, glycerin 4%, butylene glycol 3%, 1, 3-propylene glycol 3.64%, carbomer 0.5%, xanthan gum 0.15%, p-hydroxyacetophenone 0.5%, rhamnose 0.5%, arginine 0.6%, mixed extract 5%, panthenol 0.5%, caprylyl hydroxamic acid 0.07%, 1, 2-hexanediol 0.34%, bletilla striata extract 7%, willow bark extract 0.8%, methyl glucitol polyether-203%, 1, 2-pentanediol 0.4%, glycerol glucoside 0.4%, inositol 0.3%, royal jelly extract 0.8%, and the balance of water.

Slowly spreading carbomer in a preparation pot containing water and disodium ethylene diamine tetraacetate, soaking, stirring at 40Hz, and heating to 88 deg.C for dissolving;

pre-dispersing 1, 3-propylene glycol and xanthan gum, adding into a preparation pot, stirring at a frequency of 35Hz until the mixture is dissolved, sequentially adding glycerol, butanediol and p-hydroxyacetophenone into the preparation pot, stirring at a frequency of 30Hz until the mixture is completely dissolved, and then stirring and cooling;

cooling to 55 deg.C, adding rhamnose and arginine into the pot, vacuumizing to-0.04 Mpa, and stirring at 30 Hz;

cooling to 35-45 deg.C, sequentially adding the mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, rhizoma Bletillae extract, white willow bark extract, methyl glucitol polyether-20, 1, 2-pentanediol, glycerol glucoside, inositol and Lac Regis Apis extract into the preparation pot, continuously maintaining vacuum degree at-0.04 Mpa, and stirring at 25Hz to obtain the essence with anti-acne effect.

Examples of the experiments

First, the essences prepared in examples 1 to 5 were measured for their content of diethylene glycol according to QB/T5411-2019, method for measuring diethylene glycol as a non-permissible substance in cosmetics, and for their content of phenol according to the first method of chapter 2.26, fourth of technical specifications for safety of cosmetics (2015 th edition), the results of which are shown in table 1.

TABLE 1

In table 1, both diethylene glycol and phenol meet the limit requirements.

(II) the essence prepared in the examples 1 to 5 is referred to GB23200.8-2016 to chlordane, alpha-hexachloro, beta-hexachloro, delta-hexachloro, o, rho '-dichlorodiphenyl trichloroethane, rho' -dichlorodiphenyl trichloroethane, dieldrin, aldrin, dicofol and o, rho '-dizu, beta-endosulfan, alpha-endosulfan, p' -dizu, p '-dizu, omicron, rho' -dizu and gamma-hexachloro, and the results are shown in Table 2.

TABLE 2

By observing the table 2, the essence prepared in the examples 1 to 5 of the present application has no detection of the above chemicals, which shows that the essence prepared in the present application has high safety, can be used in the acne-growing period with sensitive skin conditions, and can mildly care the skin.

(III), the total number of colonies, the total number of molds and yeasts, the heat-resistant coliform group, staphylococcus aureus and Pseudomonas aeruginosa were tested according to the technical Specification for cosmetic safety (2015), with reference to the essences prepared in examples 1 to 5, and the results are shown in Table 3.

TABLE 3

According to table 3, it can be seen that the detection results of microorganisms in the essence prepared in the examples of the present application meet the requirements of technical standards for cosmetic safety (2015 edition).

(IV) the essences prepared in examples 1 to 5 were examined for mercury, lead, arsenic, cadmium and dioxane in accordance with technical Specification for cosmetic safety (2015 th edition), and the results are shown in Table 4.

TABLE 4

By observing table 4, it can be seen that the detection results of the heavy metal and dioxane of the essence prepared in the examples of the present application both meet the requirements of technical specification for cosmetic safety (2015 edition).

And (V) carrying out an acne removing efficacy experiment on the essence prepared in the embodiment 3. The test period was 4 weeks, during which the volunteers were full-face painted with the serum in the morning and evening. The number of volunteers was 10, all patients with acne graded as mild and moderate, aged 20-35 years. Testing the skin oil of the volunteer by a skin tester before and after use respectively; facial images were collected with VISIA before and after use, respectively, and the porphyrin values of the volunteer's face were analyzed. Specific results are shown in table 5.

TABLE 5

Analysis of table 5 shows that the essence prepared by the method has a good skin stabilizing effect, can effectively reduce facial oil and reduce the porphyrin value of the face, which indicates that the microbial activity of the face is low, so that pox growth can be reduced, the skin can be maintained, and the face state can be kept good. Moreover, the facial conditions of the volunteers before and after use are observed, and the facial conditions of the volunteers are found to be brightened to different degrees, which shows that the acne-removing rejuvenating essence prepared by the application can brighten the skin.

In conclusion, the acne removing cream reduces discomfort of products while increasing the acne removing effect, improves the use comfort level, replaces the irritation brought by the traditional salicylic acid with the white willow extract, extracts the compound ingredients from pure plants, has multiple acne resisting effects (bacteriostasis, oil control, keratosis resistance and inflammation relief), adopts the traditional Chinese medicine concept to treat the skin with the skin, and directly attacks the acne root cause.

The embodiments described above are some, but not all embodiments of the present application. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments in the present application without making any creative effort belong to the protection scope of the present application.

Claims

1. The acne-removing repairing rejuvenation essence is characterized by comprising the following raw materials in percentage by weight: disodium ethylenediaminetetraacetate 0.01-0.05%, glycerin 1-4%, butylene glycol 1-3%, 1, 3-propylene glycol 1.4-3.64%, carbomer 0.1-0.5%, xanthan gum 0.05-0.15%, p-hydroxyacetophenone 0.1-0.5%, rhamnose 0.1-0.5%, arginine 0.2-0.6%, mixed extract 2-5%, panthenol 0.1-0.5%, caprylyl hydroximic acid 0.01-0.07%, 1, 2-hexanediol 0.1-0.34%, bletilla striata extract 1-7%, willow bark extract 0.2-0.8%, methyl glucitol polyether-201-3%, 1, 2-pentanediol 0.15-0.4%, glycerol glucoside 0.15-0.4%, inositol 0.1-0.3%, royal jelly extract 0.2-0.8%, and the balance of water.

2. The acne treatment rejuvenation essence of claim 1 wherein the mixed extracts comprise pomegranate rind extract, mangnolia officinalis rind extract, pinus koraiensis leaf extract, citrus junos fruit extract, artemisia annua extract, water, glycerin, polysorbate-20 and dipropylene glycol.

3. The acne treatment rejuvenation essence according to claim 1 wherein the bletilla striata extracts comprise a violet bletilla striata bulb extract, butylene glycol, p-hydroxyacetophenone and 1, 2-hexanediol.

4. The acne treatment rejuvenation essence according to claim 1, wherein the acne treatment rejuvenation essence comprises the following raw materials in percentage by weight: 0.02-0.04% of disodium ethylene diamine tetraacetate, 2-3% of glycerol, 1.5-2.5% of butanediol, 2-3% of 1, 3-propylene glycol, 0.2-0.4% of carbomer, 0.08-0.12% of xanthan gum, 0.2-0.4% of p-hydroxyacetophenone, 0.2-0.4% of rhamnose, 0.3-0.5% of arginine, 2.5-5% of mixed extract, 0.3-0.4% of panthenol, 0.02-0.06% of caprylyl hydroximic acid, 0.2-0.3% of 1, 2-hexanediol, 2-6% of rhizoma bletillae extract, 0.3-0.7% of white willow bark extract, 201.5-3% of methyl glucitol polyether, 0.2-0.4% of 1, 2-0.4% of pentanediol, 0.2-0.3% of glycerol glucoside, 0.2-0.3% of inositol, 0.3-0.7% of royal jelly extract and the balance of water.

5. The preparation method of the acne treatment rejuvenation essence according to any one of claims 1 to 4, comprising the following steps:

pre-dispersing 1, 3-propylene glycol and xanthan gum, adding into a preparation pot, stirring until the mixture is dissolved, sequentially adding glycerol, butanediol and p-hydroxyacetophenone into the preparation pot, stirring until the mixture is completely dissolved, and then stirring for cooling;

after the preparation pot is cooled, adding rhamnose and arginine into the preparation pot, vacuumizing and stirring uniformly;

6. The method for preparing an acne-removing rejuvenating essence according to claim 5, wherein the carbomer is sprinkled into a pot containing water and disodium edetate, stirred and heated to 82-88 ° at a frequency of 30-40 Hz.

7. The preparation method of the acne-removing rejuvenating essence according to claim 5, wherein the 1, 3-propanediol and xanthan gum are pre-added into a preparation pot and stirred at a frequency of 25-35Hz until dissolved; the glycerol, the butanediol and the p-hydroxyacetophenone are sequentially added into a preparation pot and stirred at the frequency of 20-30Hz until the glycerol, the butanediol and the p-hydroxyacetophenone are completely dissolved.

8. The preparation method of the acne-removing rejuvenating essence according to claim 5, wherein rhamnose and arginine are added into a preparation pot when the temperature of the preparation pot is reduced to 45-55 ℃, the vacuum degree after vacuumizing is-0.04 MPa, and then the mixture is stirred to be uniform at a frequency of 20-30 Hz.

9. The method for preparing the acne-removing rejuvenating essence according to claim 5, wherein the mixed extract, panthenol, caprylyl hydroximic acid, 1, 2-hexanediol, bletilla striata extract, willow bark extract, methyl gluceth-20, 1, 2-pentanediol, glycerol glucoside, inositol, and royal jelly extract are sequentially added into the preparation pot when the temperature of the preparation pot is reduced to 35-45 ℃.

10. The preparation method of the acne treatment rejuvenation essence according to claim 5, wherein the stirring frequency of the acne treatment rejuvenation essence is 15-25Hz.