CN115429708B - Hair conditioner with scalp care and hair nourishing effects and preparation method thereof - Google Patents

Hair conditioner with scalp care and hair nourishing effects and preparation method thereof Download PDF

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CN115429708B
CN115429708B CN202211252351.2A CN202211252351A CN115429708B CN 115429708 B CN115429708 B CN 115429708B CN 202211252351 A CN202211252351 A CN 202211252351A CN 115429708 B CN115429708 B CN 115429708B
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hair
scalp care
conditioner
strontium
hair conditioner
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CN115429708A (en
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段东平
李婷
任玉枝
黄伟文
杨天云
梁结时
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Guangxi Hegui Group Co ltd
Institute of Process Engineering of CAS
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Guangxi Hegui Group Co ltd
Institute of Process Engineering of CAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

Abstract

The invention relates to a hair conditioner with scalp care and hair nourishing effects and a preparation method thereof. The invention creatively adds the strontium-containing compound into the hair care product, utilizes the biological activities of strontium element such as promoting collagen formation, inducing angiogenesis, promoting cell endothelial proliferation and the like to keep scalp activity, nourish hair follicles, maintain the basic environment of hair growth, further grows stronger and healthier hair, and strontium enters the human body through the scalp to supplement microelements. Furthermore, the copper peptide can promote proliferation of hair papilla cells and expression of hair growth factors, has the effects of resisting hair follicle aging, preventing alopecia, promoting hair growth, promoting wound healing and the like, and creatively combines the copper peptide with a strontium-containing compound for use, so that the copper peptide has a synergistic effect in scalp care.

Description

Hair conditioner with scalp care and hair nourishing effects and preparation method thereof
Technical Field
The invention belongs to the technical field of daily chemical products, and particularly relates to a hair conditioner with scalp care and hair nourishing effects and a preparation method thereof.
Background
The condition of a person's hair often reflects much information about the person, such as health status, mental aspects, mind, life habits, etc., so people are also increasingly paying attention to hair care of individuals. The maintenance of hair comprises scalp care and hair nourishing, and the hair care products which can achieve the two effects are always independent, for example, essential oil aiming at scalp and hair conditioner and hair mask aiming at hair, so that two working procedures are designed, and the operation is troublesome.
And most of active ingredients in the existing scalp care products are traditional Chinese medicine plant extracts, plant essential oil, protein amino acid, organic skin penetrating agents, grease, surfactants with cleaning effect and the like. However, the proportion of the organic components which are large molecular substances and can be actually absorbed by skin cells is not well defined.
CN112022749a discloses a hair conditioning composition with scalp barrier enhancing effect, and its preparation method and application, which comprises the following raw materials in weight percentage: 5-20% of plant sterol ester, 50-80% of trimethylolpropane triester, 5-20% of B vitamins, 1-20% of natural vegetable oil and 1-15% of water-soluble grease. The composition can be used for preparing shampoo, hair conditioner, hair treatment cream or hair mask, and has effects of moistening scalp, enhancing scalp barrier, nourishing hair follicle, and ensuring smooth hair and refreshing scalp. However, the scalp care ingredients in the invention are plant sterol ester, trimethylolpropane triester, B vitamins, natural vegetable oil and water-soluble grease which are all organic matters, and the scalp care composition has the problem that the scalp care composition is large in molecular particle size and is not easy to absorb.
CN113476354a discloses an anti-hair loss hair-growing conditioner, which comprises the following components in percentage by mass: 1-6% of thickening agent, 1-2% of cationic surfactant, 1-10% of proline, 0.1-0.5% of cacumen biotae extract, 0.1-0.5% of ginseng extract, 0.1-1% of ginger extract, 0.1-1% of cordyceps militaris extract, 0.1-1% of astragalus membranaceus root extract, 0.1-2% of saccharide isomer and the balance of water. The hair conditioner can maintain scalp environment steady state, activate germinal cell proliferation and differentiation, repair hair follicle structure, reestablish skin barrier, effectively fix and nourish hair, and promote hair growth. However, although the plant extracts are common raw materials of daily chemical varieties, the components of each extract are very complex, and the stability of the components of each batch of samples can not be guaranteed in practical application.
Therefore, it is very significant to develop a hair care product which is easily absorbed by the scalp, has safe ingredients and has the effects of scalp care and hair nourishing.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a hair conditioner with scalp care and hair nourishing effects and a preparation method thereof.
In order to achieve the aim of the invention, the invention adopts the following technical scheme:
in a first aspect, the present invention provides a hair conditioner having both scalp care and hair nourishing effects, the hair conditioner comprising: conditioning agent, surfactant, thickener, humectant, pH regulator, antiseptic and deionized water; the conditioning agent comprises a strontium containing compound.
Strontium is an essential trace element for maintaining the growth of a living body, the strontium plays various biological activities in the human body, the particle size of strontium ions is tiny, and compared with organic macromolecules, the strontium ions are easier to permeate into skin and hair.
Preferably, the strontium-containing compound comprises any one or a combination of at least two of strontium chloride, strontium chloride hexahydrate, strontium hydroxide, strontium acetate, strontium citrate, strontium peroxide; the at least two combinations may be selected, for example, a combination of strontium chloride and strontium chloride hexahydrate, a combination of strontium chloride and strontium acetate, a combination of strontium chloride and strontium hydroxide, a combination of strontium chloride and strontium citrate, etc., and any other combination manner will not be described in detail herein.
The strontium-containing compound can play roles in keeping scalp activity, nourishing hair follicles and maintaining the basic environment for hair growth, and strontium chloride hexahydrate is a better adding mode.
The hair conditioner is compounded by using components such as strontium-containing compounds, other conditioning agents, surfactants, thickening agents, moisturizers, pH regulators, preservatives and the like, and all the raw materials mutually promote, so that the hair conditioner has the effects of scalp care and hair nourishing.
Preferably, the conditioning agent further comprises a copper peptide.
The copper peptide can promote proliferation of hair papilla cells and expression of hair growth factor, has effects of resisting hair follicle aging, preventing alopecia, protecting injured tissue from oxidation and further damage, and promoting hair growth and wound healing. It also has effects in maintaining skin support structure (such as collagen, glycoprotein, elastin, etc.), reducing coarse and fine wrinkles, and inhibiting inflammation. The invention also creatively discovers that the copper peptide and the strontium-containing compound are matched for use, and has a synergistic effect in scalp care.
Preferably, the mass ratio of the copper peptide to the strontium-containing compound is 1:10-10:1, for example, 1:10, 1:9, 1:8, 1:6, 1:5, 1:3, 1:2, 1:1, 2:1, 3:1, 5:1, 10:1, etc., and other specific values within the numerical range are selected, and will not be described in detail herein.
Preferably, the conditioning agent further comprises any one or a combination of at least two of hydrolyzed silk protein, silicone oil or polyvinylpyrrolidone; preferably a combination of hydrolyzed silk proteins, silicone oils and polyvinylpyrrolidone.
The hydrolyzed silk protein can be crosslinked with protein groups exposed at damaged parts of the hair, so that the damage is repaired, and the toughness of the hair is improved; the silicone oil (or silicone oil emulsion) can greatly increase the flexibility and glossiness of the hair; the polyvinylpyrrolidone has good film forming property, a layer of protective film is formed on the hair surface, and the nutrition and the soft ingredients are locked in the hair scales of the hair and are not easy to wash off, so that the hair conditioner can play a long-acting role; the hair conditioner also plays a role in moisturizing, so that the hair can be kept in a smooth state for a longer time; but also increases the elasticity and shaping effect of the hairline; and meanwhile, the external environment can be blocked outside, so that the scalp and hairline are protected from pollution.
Preferably, the silicone oil comprises any one or a combination of at least two of the following: (1) Amino terminal polydimethyl siloxane and cetrimide and tridecyl alcohol polyether-12; (2) Polydimethyl siloxane and laureth-23 and C12-15 alkanolamine polyether-3; (3) Cyclic pentamethylenes and dimethiconols.
Preferably, the surfactant comprises any one or a combination of at least two of cetyltrimethylammonium chloride, hard amidopropyl dimethylamine, cetostearyl alcohol and polyethylene glycol stearate.
The combination of at least two of the above compounds, such as cetyltrimethylammonium chloride and cetostearyl alcohol, and hard amidopropyl dimethylamine and polyethylene glycol stearate, may be selected, and any other combination will not be described here.
Wherein cationic surfactants such as cetyl trimethyl ammonium chloride and hard amidopropyl dimethylamine in the surfactant can neutralize the molecules with anions remained on the surface of the hair in the shampoo to form a monomolecular film, so that tangled hair is taken along, easy to comb, and plays roles of antistatic and softening hair. Wherein, the cetostearyl alcohol and the polyethylene glycol stearate can keep the oil-water balance of the system and stabilize the system.
Preferably, the thickener comprises any one or a combination of at least two of hydroxyethyl cellulose, sodium polyacrylate grafted starch, hydroxypropyl guar, ammonium acryloyldimethyl taurate/VP copolymer, sodium polyacrylate or acrylic acid (ester) type/C10-30 alkanol acrylate cross-linked polymer. Has thickening and stabilizing effects.
Preferably, the humectant comprises any one or a combination of at least two of hyaluronic acid, hyaluronate, propylene glycol, glycerol, dipropylene glycol, trehalose; hyaluronic acid and/or hyaluronate are preferred.
Preferably, the hyaluronic acid is a combination of macromolecular hyaluronic acid, medium molecular hyaluronic acid and small molecular hyaluronic acid; the macromolecular hyaluronic acid refers to hyaluronic acid with molecular weight larger than 5000, the medium molecular hyaluronic acid refers to hyaluronic acid with molecular weight of 1000-5000, and the small molecular hyaluronic acid refers to hyaluronic acid with molecular weight smaller than 1000.
Wherein the macromolecular hyaluronic acid can form a layer of breathable film on the surfaces of scalp and hair to make skin smooth and moist, and can prevent invasion of foreign bacteria, dust and ultraviolet rays and protect skin from invasion; the medium-molecular hyaluronic acid can tighten the scalp and keep moisture for a long time; the small molecule hyaluronic acid can permeate into dermis, has the functions of slightly expanding capillary vessels, increasing blood circulation, improving intermediate metabolism and promoting nutrient absorption of scalp, and can increase skin elasticity and delay skin aging. And the hyaluronic acid can be combined with strontium ions in the strontium-containing compound to react to generate strontium hyaluronate, so that the strontium metal ions can be more stably existing in the hair conditioner system, and other easily crystallized strontium salts are prevented from being separated out.
Preferably, the hyaluronate is a combination of macromolecular hyaluronate, medium molecular hyaluronate and small molecular hyaluronate.
Preferably, the conditioner further comprises: any one or a combination of at least two of a lipid-rich agent, a fragrance, and a chelating agent; the combination of at least two of the above-mentioned compounds, such as a combination of a fat-rich agent and a fragrance, a combination of a fragrance and a chelating agent, a combination of a fat-rich agent and a chelating agent, etc., may be selected, and any other combination will not be described here.
Preferably, the lipid-rich agent comprises water-soluble lanolin. The lipid-rich agent can maintain lipid balance of scalp and hair, reduce external irritation, relieve dry skin, and improve hair comb property.
In a second aspect, the present invention provides a method for preparing a hair conditioner having scalp care and hair nourishing effects as described in the first aspect, the method comprising: mixing and homogenizing the raw material components of the hair conditioner.
Preferably, the preparation method comprises the following steps:
(1) Mixing a thickening agent with deionized water, homogenizing and stirring, mixing with a surfactant for dispersion, and heating to obtain a matrix A;
(2) Mixing and stirring the matrix A and the conditioner to obtain a matrix B;
(3) Mixing matrix B with humectant and antiseptic, and regulating pH with pH regulator.
Preferably, the heating to 75-90 ℃ in step (1), such as 75 ℃, 78 ℃, 80 ℃, 82 ℃, 85 ℃, 87 ℃, 88 ℃, 90 ℃ and the like, and other specific values within the numerical range can be selected, and will not be described in detail herein.
Preferably, the mixing and stirring in the step (2) is performed at 30-50 ℃, for example, 30 ℃, 35 ℃, 40 ℃, 45 ℃, 50 ℃, etc., and other specific values within the numerical range can be selected, so that the details are not repeated here.
Preferably, in the step (3), the pH is adjusted to 4.0-8.0, for example, ph=4.0, ph=4.5, ph=5.0, ph=5.5, ph=6.0, ph=6.5, ph=7.0, ph=8.0, and other specific values within the range of values are selected, and will not be described in detail herein.
The hair conditioner prepared by the preparation method of the specific technical parameters is stable in system and durable in efficacy.
Compared with the prior art, the invention has the following beneficial effects:
the invention creatively adds the strontium-containing compound into the hair care product, utilizes the biological activities of strontium element such as promoting collagen formation, inducing angiogenesis, promoting cell endothelial proliferation and the like to keep scalp activity, nourish hair follicles, maintain the basic environment of hair growth, further grows stronger and healthier hair, and strontium enters the human body through the scalp to supplement microelements.
Furthermore, the copper peptide can promote proliferation of hair papilla cells and expression of hair growth factors, resist hair follicle aging and alopecia, is used as a powerful tissue protecting and anti-inflammatory agent for protecting injured tissues from further damage due to oxidization, has the effects of promoting hair growth, wound healing and the like, and also creatively combines the copper peptide with a strontium-containing compound for use, so that the copper peptide has a synergistic effect in scalp care.
Detailed Description
In order to further describe the technical means adopted by the present invention and the effects thereof, the following describes the technical scheme of the present invention in combination with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.
The following examples and comparative examples relate to the partial source information as follows:
the hydrolyzed silk protein is hydrolyzed silk protein purchased from Zhengzhou Yu control biotechnology limited company;
the amino silicone oil emulsion is MEM-0949 amino silicone oil emulsion;
the organosilicon emulsion is SSE-762 organosilicon emulsion;
the polyvinylpyrrolidone is polyvinylpyrrolidone K30;
polyethylene glycol stearate is polyethylene glycol 6000 distearate;
the hyaluronic acid is a mixture of macromolecular hyaluronic acid (QuFu Ling market sea biological products Co., ltd.), medium molecular hyaluronic acid (Zhengzhou Ming Rui chemical products Co., ltd.), and small molecular hyaluronic acid (Sian Qiano biological technologies Co., ltd.) in a mass ratio of 1:2:1;
the preservative is a Jack BP water-soluble antibacterial agent;
other raw materials are all purchased through commercial routes.
Example 1
The embodiment provides a hair conditioner with scalp care and hair nourishing effects, which comprises the following components in percentage by mass: 2% of strontium chloride, 1% of copper peptide, 2.5% of hydrolyzed silk protein, 1% of amino silicone oil emulsion, 1.5% of polyvinylpyrrolidone, 2% of cetyltrimethylammonium chloride, 2% of cetostearyl alcohol, 0.5% of hydroxyethyl cellulose, 3.5% of hyaluronic acid, 2% of propylene glycol, 0.5% of citric acid, 0.2% of preservative, 1% of water-soluble lanolin and the balance of deionized water.
The preparation method comprises the following steps:
(1) Mixing hydroxyethyl cellulose with deionized water, homogenizing and stirring, mixing with cetyltrimethylammonium chloride and cetylstearyl alcohol for dispersion, and heating to 80deg.C to obtain matrix A;
(2) Mixing and stirring the matrix A, strontium chloride, copper peptide, hydrolyzed silk protein, amino silicone oil emulsion and polyvinylpyrrolidone at 40 ℃ to obtain a matrix B;
(3) Mixing matrix B with hyaluronic acid, propylene glycol, antiseptic, and water soluble lanolin, and adjusting pH with citric acid.
Example 2
The embodiment provides a hair conditioner with scalp care and hair nourishing effects, which comprises the following components in percentage by mass: 3.5% of strontium chloride hexahydrate, 2% of copper peptide, 1.5% of hydrolyzed silk protein, 1.5% of organic silicon emulsion, 2% of polyvinylpyrrolidone, 2% of hard amidopropyl dimethylamine, 2% of polyethylene glycol stearate, 0.5% of hydroxyethyl cellulose, 3% of hyaluronic acid, 2% of panthenol, 0.5% of citric acid, 0.2% of preservative, 1% of water-soluble lanolin and the balance of deionized water.
The preparation method comprises the following steps:
(1) Mixing hydroxyethyl cellulose with deionized water, homogenizing and stirring, mixing with hard amidopropyl dimethylamine and polyethylene glycol stearate for dispersion, and heating to 75 ℃ to obtain a matrix A;
(2) Mixing and stirring the matrix A, strontium chloride, copper peptide, hydrolyzed silk protein, organosilicon emulsion and polyvinylpyrrolidone at 30 ℃ to obtain a matrix B;
(3) Mixing matrix B with hyaluronic acid, panthenol, antiseptic, and water-soluble lanolin, and adjusting pH with citric acid.
Example 3
The present example provides a hair conditioner with scalp care and hair nourishing effects, which differs from example 1 only in that 2% of strontium chloride is replaced by 3.3% of strontium chloride hexahydrate, and other components and contents remain unchanged. The preparation method is described in example 1.
Example 4
The present example provides a hair conditioner with scalp care and hair nourishing effects, and the composition formula is different from that of example 1 only in that 2% of strontium chloride and 1% of copper peptide are replaced by 3% of strontium chloride, and other components and contents are kept unchanged. The preparation method is described in example 1.
Example 5
The present example provides a hair conditioner with scalp care and hair nourishing effects, and the composition formula is different from that of example 1 only in that 2% of strontium chloride and 1% of copper peptide are replaced by 3% of copper peptide, and other components and contents are kept unchanged. The preparation method is described in example 1.
Example 6
The present example provides a hair conditioner with scalp care and hair nourishing effects, and the composition formula is different from that of example 1 only in that 3.5% of hyaluronic acid and 2% of propylene glycol are replaced by 5.5% of propylene glycol, and other components and contents are kept unchanged. The preparation method is described in example 1.
Example 7
The present example provides a hair conditioner with scalp care and hair nourishing effects, which is different from example 1 in that the hair conditioner does not contain polyvinylpyrrolidone, the content of which is complemented by deionized water, and the other components and the content of which are all kept unchanged. The preparation method is described in example 1.
Example 8
The present example provides a hair conditioner having both scalp care and hair nourishing effects, which differs from example 1 only in that the composition formulation does not contain hydrolyzed silk proteins, the content thereof is distributed to the contents of amino silicone oil emulsion and polyvinylpyrrolidone, and the mass ratio of amino silicone oil emulsion and polyvinylpyrrolidone is kept unchanged. Other conditions remained consistent.
Example 9
The present example provides a hair conditioner having both scalp care and hair nourishing effects, which differs from example 1 only in that the composition formulation does not contain an amino silicone oil emulsion, the content of which is distributed to the content of hydrolyzed silk protein and polyvinylpyrrolidone, and the mass ratio of hydrolyzed silk protein and polyvinylpyrrolidone is kept unchanged. Other conditions remained consistent.
Example 10
The present example provides a hair conditioner having both scalp care and hair nourishing effects, which differs from example 1 only in that it does not contain polyvinylpyrrolidone, its content is distributed to the contents of amino silicone oil emulsion and hydrolyzed silk protein, and the mass ratio of amino silicone oil emulsion and hydrolyzed silk protein is kept unchanged. Other conditions remained consistent.
Comparative example 1
The comparative example provides a hair conditioner which differs from example 1 only in that it does not contain strontium chloride, and is supplemented with deionized water, and other components and contents remain unchanged. The preparation method is described in example 1.
Test example 1
The hair conditioners prepared in examples 1 to 10 were evaluated for safety performance:
100 social volunteers meeting the requirements are selected, the ages of the social volunteers are 20-45, the social volunteers are randomly divided into 10 groups, 5 women and 5 men are respectively tested according to the groups, the hair conditioner prepared in the examples 1-10 is respectively taken, 0.020-0.025mL of tested samples are respectively put into a plaque tester cell, and no treatment is carried out on the control hole. The patch test with the test object is applied to the back or forearm of the subject with hypoallergenic tape, and is applied to the skin with palm light pressure for 24 hr. Skin reactions were observed according to the table 1 standard 30min after removal of the plaque, 24h and 48h, respectively (after disappearance of the indentations). The test results are shown in Table 2.
TABLE 1
TABLE 2
The results show that: examples 1-10 of the present invention are all negative reactions, demonstrating that the hair conditioner of the present invention is safe and mild and does not produce adverse reactions such as skin irritation, sensitization, etc.
Test example 2
220 volunteers of general alopecia patients who are losing hair (about 200 average alopecia patients per day) were randomly selected, and the male and female halves, 23-55 years old, were divided into experimental group 1-10, comparative example group 1, 20 people each, 10 men and 10 women. The using method comprises the following steps: before use, hair and scalp are cleaned, 5mL of each group of products are uniformly rubbed on the scalp and hair in a wet state, the scalp and hair are massaged for 5min until the products are absorbed, finally, the scalp and the hair are cleaned by clean water, the hair is used once every 3 days, the test time is 90 days, the growth condition of the hair of each group of volunteers is observed, each group is averaged, and the results are shown in the table 3 (the results are presented as the average):
TABLE 3 Table 3
As can be seen from the data in table 3: the hair conditioner has the effects of obviously stimulating scalp hair follicles, promoting hair growth and regeneration and preventing alopecia, and the strontium-containing compound and the copper peptide have obvious synergistic effect on the effects, and meanwhile, the specific types of the strontium-containing compound, the addition of polyvinylpyrrolidone and the addition of hyaluronic acid can influence the technical effects.
Test example 3
Hair contact angle and smoothness evaluation:
the contact angle can be used to characterize the hydrophilicity of the hair surface, the larger the contact angle, the better the hydrophobicity of the hair and the higher the health degree of the hair, 10 hairs are randomly selected by each volunteer in test example 2, the contact angle test is carried out by using deionized water, the change condition of the contact angle before and after the shampoo is used is compared and is divided into 3 grades (the unchanged range is within 0.1%, the larger range and the smaller range), and the number of people in each grade is recorded. The results are shown in Table 4.
The smoothness was determined by the coefficient of friction, 10 hairs were randomly selected from each volunteer in test example 2 and fixed on a slide glass, and then the hairs were combed and slid from the root to the tip of the hair by a detector, and the average coefficient of friction was measured and divided into three classes (0.15 or less, 0.15 to 0.20, 0.20 or more) and the number of people in each class was recorded. The results are shown in Table 4.
TABLE 4 Table 4
As can be seen from the data in table 4: the volunteers have significantly improved hydrophobicity and smoothness of hair after using the hair conditioner according to the present invention. And the composition formulation of the conditioner significantly affects its effect on the hydrophobicity and smoothness of hair.
The applicant states that the present invention is described by the above examples as a hair conditioner having both scalp care and hair nourishing effects and a method for preparing the same, but the present invention is not limited to the above examples, i.e., it does not mean that the present invention must be practiced by relying on the above examples. It should be apparent to those skilled in the art that any modification of the present invention, equivalent substitution of raw materials for the product of the present invention, addition of auxiliary components, selection of specific modes, etc., falls within the scope of the present invention and the scope of disclosure.
The preferred embodiments of the present invention have been described in detail above, but the present invention is not limited to the specific details of the above embodiments, and various simple modifications can be made to the technical solution of the present invention within the scope of the technical concept of the present invention, and all the simple modifications belong to the protection scope of the present invention.
In addition, the specific features described in the above embodiments may be combined in any suitable manner, and in order to avoid unnecessary repetition, various possible combinations are not described further.

Claims (17)

1. A hair conditioner with scalp care and hair nourishing effects, which is characterized by comprising: conditioning agent, surfactant, thickener, humectant, pH regulator, antiseptic and deionized water; the conditioner comprises a strontium-containing compound and a copper peptide in a mass ratio of 1:10-10:1; the strontium-containing compound comprises any one or a combination of at least two of strontium chloride, strontium chloride hexahydrate, strontium acetate and strontium citrate.
2. A hair conditioner having both scalp care and hair nourishing effects as claimed in claim 1, wherein the conditioner further comprises any one or a combination of at least two of hydrolyzed silk protein, silicone oil or polyvinylpyrrolidone.
3. A hair conditioner having both scalp care and hair tonic effects as claimed in claim 2, wherein the conditioner further comprises a combination of hydrolyzed silk protein, silicone oil and polyvinylpyrrolidone.
4. A hair conditioner having both scalp care and hair nourishing effects as claimed in claim 3, wherein the silicone oil comprises any one or a combination of at least two of the following: (1) Amino terminal polydimethyl siloxane and cetrimide and tridecyl alcohol polyether-12; (2) Polydimethyl siloxane and laureth-23 and C12-15 alkanolamine polyether-3; (3) Cyclic pentamethylenes and dimethiconols.
5. A hair conditioner having both scalp care and hair nourishing effects as claimed in claim 1, wherein the surfactant comprises any one or a combination of at least two of cetyltrimethylammonium chloride, hard amidopropyl dimethylamine, cetostearyl alcohol, polyethylene glycol stearate.
6. A hair conditioner having both scalp care and hair nourishing effects according to claim 1 wherein said thickener comprises any one or a combination of at least two of hydroxyethyl cellulose, sodium polyacrylate grafted starch, hydroxypropyl guar, ammonium acryloyldimethyl taurate/VP copolymer, sodium polyacrylate or acrylic acid (ester) type/C10-30 alkanol acrylate cross-linked polymer.
7. The hair conditioner having both scalp care and hair nourishing effects according to claim 1, wherein the moisturizer comprises any one or a combination of at least two of hyaluronic acid, hyaluronate, propylene glycol, glycerol, glycerin, dipropylene glycol, and trehalose.
8. A hair conditioner having both scalp care and hair tonic effects as claimed in claim 7, wherein said moisturizer comprises hyaluronic acid and/or hyaluronate.
9. The hair conditioner with scalp care and hair nourishing effects as claimed in claim 8, wherein the hyaluronic acid is a combination of macromolecular hyaluronic acid, medium molecular hyaluronic acid and small molecular hyaluronic acid.
10. The hair conditioner with scalp care and hair nourishing effects according to claim 8, wherein the hyaluronate is a combination of macromolecular hyaluronate, medium molecular hyaluronate and small molecular hyaluronate.
11. The hair conditioner with scalp care and hair nourishing effects as claimed in claim 1, wherein the hair conditioner further comprises: any one or a combination of at least two of a lipid-rich agent, a fragrance, and a chelating agent.
12. A hair conditioner having both scalp care and hair nourishing effects as claimed in claim 11 wherein said lipid rich agent comprises water soluble lanolin.
13. A method for preparing a hair conditioner having scalp care and hair nourishing effects according to any one of claims 1 to 12, wherein the method comprises: mixing and homogenizing the raw material components of the hair conditioner.
14. The method for preparing a hair conditioner having scalp care and hair nourishing effects as claimed in claim 13, wherein the method comprises the steps of:
(1) Mixing a thickening agent with deionized water, homogenizing and stirring, mixing with a surfactant for dispersion, and heating to obtain a matrix A;
(2) Mixing and stirring the matrix A and the conditioner to obtain a matrix B;
(3) Mixing matrix B with humectant and antiseptic, and regulating pH with pH regulator.
15. The method for preparing a hair conditioner having scalp care and hair nourishing effects as claimed in claim 14, wherein the heating in step (1) is performed to 75-90 ℃.
16. The method for preparing a hair conditioner having scalp care and hair nourishing effects as claimed in claim 14, wherein the mixing and stirring in the step (2) are carried out at 30-50 ℃.
17. The method for preparing a hair conditioner having scalp care and hair nourishing effects as claimed in claim 14, wherein the pH is adjusted to 4.0-8.0 in the step (3).
CN202211252351.2A 2021-12-31 2022-10-13 Hair conditioner with scalp care and hair nourishing effects and preparation method thereof Active CN115429708B (en)

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