CN104856892A - Cosmetic or skin care product preparation rich in growth factors and preparation method therefor - Google Patents
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Abstract
The invention relates to the cosmetic technology field, and especially relates to a cosmetic or skin care product preparation rich in growth factors and a preparation method therefor. A cosmetic or skin care product preparation rich in growth factors and composed of main ingredients: cell growth factors, micromolecule polypeptides, water, grease, surfactants, humectants, anti-oxidants and preservatives and a preparation method are provided. Through mutual cooperation of ingredients, the composition preparation can accelerate metabolism of skin cells, restore fractured shallow epidermal layer fibrocytes, has protruding rapid restoration function to skin wound surfaces, and has a plurality of functions of whitening, wrinkle removing, calmness, anti-allergy, skin smoothing, anti-wrinkle, brightening, refreshing, anti-aging, anti-radiation, stain prevention and reduction and the like.
Description
Technical field
The present invention relates to cosmetic technical field, particularly relate to a kind of cosmetics or skin care item preparation and preparation method thereof that are rich in somatomedin.
Background technology
The develop rapidly of modern science and technology and extensive use, bring brand-new opportunity to develop to cosmetics industry, and skin care item are chemically improved looks, plant beauty develops to biological beauty, gene beauty treatment.The main component biologically active polypeptide major part of biological skin care item is cell growth factor, content is atomic in vivo for they, but biological activity is high, biological regulation effect is played to various kinds of cell physiological function and metabolic activity, affect the growth of polytype cell, division, differentiation, propagation and migration directly or indirectly, play an important role in beauty and skin care, plastic surgery, burn ulcer and various dermopathic wound repair with healing.
Main somatomedin comprises fibroblast growth factor (Fibroblast growth factors, FGFs), human epidermal growth factor (human epidermal growth factor, hEGF), keratinocyte growth factor (keratinocyte growthfactor, and vascular endothelial cell growth factor (vascular endothelial growth factor, VEGF) etc. KGF).Wherein FGFs receives much concern in recent years, and FGFs has 23 members at present, wherein importantly mainly comprises acid fibroblast growth factor (aFGF) and basic fibroblast growth factor (bFGF).
In somatomedin, EGF can promote epidermal growth, and repair epidermis, FGF can promote fibroblastic growth, accelerates collagenation.KGF can promote horn cell eccrine fiber albumen, maintains cell elasticity, and the composite of several factor can the improvement of promotion skin texture from inside to outside, accelerates skin repair speed, reduces cicatrix and produce.
Micromolecule victory peptide plays an important role in the growth of biology, growth and metabolism.The polypeptide that various physiological processes in human body are nearly all made up of specific aminoacid sequence or protein regulation.In skin natural aging and nursing process, victory peptide plays an important role, as cell proliferation, cell migration, inflammation, blood vessel generation, chromogenesis and albumen biosynthesis and regulation.Wherein palmityl signal self-shield can promote the synthesis of stromatin (matrix protein) especially collagen protein, also may increase the generation of elastin laminin, hyaluronic acid, glycosaminoglycans and fibronectin simultaneously.Copper Toplink impels the growth of neurocyte, immunity-associated cell, division and differentiation, effectively can promote wound healing.
Different action receptors makes the synergism of somatomedin and the composite rear generation of micromolecule victory peptide further promote skin metabolism, speckle dispelling reduce wrinkle, add the combined effect of all the other compositions in cosmetics, prevent skin aging, repair impaired skin, improve skin, composite Be very effective is better than being used alone comprehensively.
At present; research report about this respect is also a lot; the patent of invention of publication No. CN102406556A discloses one and contributes to keeping the bioactive cosmetics of epidermal growth factor or skin care item preparation; said preparation main component is epidermal growth factor, hydrolytic collagen, hyaluronate sodium, silk peptide powder, Matrixyl and carnosine, substrate and water, is reached in cosmetic formulations keep the bioactive effect of skin factor by multicomponent protective effect.Publication No. is that the patent of invention of US20140228291A1 discloses a kind of skin-care gel and using method thereof, and this gel is by cyclic dimethyl polysiloxane, EGF, TGF β
1, the material such as FGF and palmitoyl oligopeptide is prepared from.But because each material used is different, content is inconsistent, product on skin the effect that rises also different.
Summary of the invention
The object of this invention is to provide a kind of cosmetics or skin care item preparation and preparation method thereof that are rich in somatomedin.
In order to realize this object, present invention employs following technical scheme:
Be rich in cosmetics or the skin care item preparation of somatomedin, it is characterized in that: main component is cell growth factor, micromolecule victory peptide, water, oils and fats, surfactant, wetting agent, antioxidant, antiseptic.
As further improvement, described cell growth factor accounts for preparation gross mass 0.0001 ~ 0.001%, and described micromolecule victory peptide accounts for 0.0001 ~ 0.002% of preparation gross mass.
As further improvement, described somatomedin comprises keratinocyte growth factor, acid fibroblast growth factor, a kind of cosmetics or skin care item preparation being rich in somatomedin of alkaline fibroblast, it is characterized in that: the one or more combination thing in dimension cell growth factor, platelet derived growth factor and epidermal growth factor.
As further improvement, described somatomedin all derives from technique for gene engineering by engineering bacteria fermentation purification gained.
As further improvement, described micromolecule victory peptide comprises one or more in palmityl tripeptides-1, Matrixyl-3, palmityl tripeptides-5, palmityl six peptide-6, palmityl six peptide-9, acetyl tetrapeptide-5, copper peptide, class N-GEECDCGSPENPCCD.
As further improvement, described oils and fats is one or more in olive oil, castor oil hydrogenated, caprylic/capric triglyceride, Oleum Gossypii semen, soybean oil, Oleum Hippophae, Jojoba oil, squalane, lanonol, cetearyl alcohol, polydimethylsiloxane, PSI, cyclic polysiloxanes, and its consumption is: 1%-10%;
Described surfactant is one or more in polysorbas20, Tween 80, sodium laurate, stearyl alcohol sodium sulfate, polyoxyethylene fatty acid ester, ceteareth-2, ceteareth-21, Phosphoric acid monohexadecyl ester, and its consumption is: 1%-10%;
Described wetting agent is one or more in pyrrolidone sodium carboxylate, chondroitin sulfate, glycerol, propylene glycol, hyaluronate sodium, trimethyl glycine, methylglycine proline, xylitol, anhydro xylitol, xylitol glucoside, and its consumption is: 1%-15%;
Described preparation also comprises pH adjusting agent, and described pH adjusting agent is any one in citric acid-sodium citrate, lactic acid-sodium lactate, and its consumption is: 0.1%-3%;
Described antioxidant is one or more in vitamin C, vitamin E, riboflavin class, nicotinic acid class, metallothionein, superoxide dismutase and dimethylglycine, and its consumption is: 0.1%-1%;
Described antiseptic is one or more in methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben, dimethyloldimethylhydantoin, diazolidinyl urea, IPBC and iodine propilolic alcohol butyl mephenesin Carbamate, and its consumption is: 0.05%-0.2%;
Described cosmetics or skin care item dosage form are any one in cream, Emulsion, essence lotion, gel and facial film.
The present invention, except above-mentioned necessary formulation ingredients, can also reach by other natural plant extracts composite and active component the object promoting repair.Such as, composite have one or more the composite composition be selected from Radix Glycyrrhizae extract, Radix Pulsatillae extract, Pericarpium Zanthoxyli extract, Flos Hibisci extract, Semen Vitis viniferae extract and chicory root extract etc.Wherein said composite composition accounts for 0.01% ~ 10% of described cosmetics or skin care item gross mass, and preferably 0.1% ~ 5%.
Present invention also offers the preparation method of above-mentioned cosmetics or skin care item combination, comprise the following steps:
Stir 5min after oils and fats and surfactant are heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C;
(1) stir 5min after oils and fats and surfactant being heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C;
(2) by cell growth factor and micromolecule victory peptide and antioxidant and/or natural plant extracts deionized water dissolving for subsequent use, described deionized water consumption is: can make the consumption that cell growth factor and micromolecule victory peptide and antioxidant and/or natural plant extracts are just dissolved;
(3) material in step (2) is added in the material in (1), stir 3min and make it even;
(4) by one or several mixed dissolutions in wetting agent, pH adjusting agent, preservative component and the mixed solution added in step (3) stir and get final product.
The present invention, relative to prior art, has the following advantages:
In inventive compound, the combination of somatomedin and micromolecule victory peptide can promote fibroblastic growth promoter, constantly replaces aging cell with new cell, and therefore percutaneous renewal produces wrinkle resistant, wrinkle removal effect; Upgrade senile cell, thus reduce the content of melanin and coloured corpuscle in skin, alleviate cutaneous pigmentation.In addition, accelerate the metabolism of pigment by improving microcirculation, thus reach desalination pigment and ruddy skin effect; The formation of chafe granulation tissue and the epithelization of promotion granulation tissue, also scalable collagen degradation and renewal, thus play the effect shortened the wound healing time and reduce cicatrization.
Described wetting agent is pure natural structural material, absorbs fast, active high and have high biological compatibility, very easily water-soluble, very heat-resisting, acidproof and alkaline-resisting and applied widely, safety and stability.In addition also have soft skin, crease-resistant, brighten, salubrious effect.Be applied in personal care product, skin histology can be entered by rapid permeability, improve the moisture holding capacity of skin, the vigor of activated cell, give skin gloss and salubrious effect of moistening.
Metallothionein (MT) in antioxidant has superpower radical scavenging activity, its ability removing OH free radical is 100 times of GSH-Px (glutathion peroxidase), is 1000 times of SOD (superoxide dismutase).By blocking the peroxidization of the unsaturated fatty acid in free radical and body, reduce the content of lipid peroxide in skin, reduce the generation of melanin, lipofuscin and ceroid, be applied in cosmetics as bio-activator, defying age, radioprotective can be played, prevent and alleviate the multiple efficacies such as mottle.
The natural plant extracts that the present invention adds works in coordination with the skin repair effect of bioactive ingredients, has possessed again the multiple action of whitening wrinkle-removing, calm antiallergic simultaneously, has considerably increased the scope of application and the compliance of preparation.
Between the formula of this cosmetic formulations, collocation can accelerate the metabolism of Skin Cell mutually, repairs the shallow epidermal area fibrocyte of fracture, has outstanding quick repair function to skin wound.Be applied to the various damages of skin histology, remove skin sore, acne, go the little defect after nevus, change the skin burn that the decortication after skin, rubescent, fruit acid etc. cause, the epidermis injury reparation etc. after grinding has outstanding effect.
Detailed description of the invention
The present invention will be described to enumerate a part of specific embodiment below, be necessary to herein means out be following specific embodiment only for the present invention is further illustrated, do not represent limiting the scope of the invention.Some nonessential amendments that other people make according to the present invention and adjustment still belong to protection scope of the present invention.
Embodiment 1 skin repair emulsion
Component and the relative content of the product of composition emulsion are:
Preparation method:
(1) stir 5min after A group being heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C.
(2) dissolve for subsequent use by component C appropriate amount of deionized water, described deionized water consumption is: can make the consumption that solid matter just dissolves;
(3) component C is added in component A, stir 3min and make it even.
(4) mixed solution B component of prior mixed dissolution being added above-mentioned two components stirs and get final product.
Embodiment 2 skin repair frost
Component and the relative content of the product of composition frost are:
Preparation method:
(1) stir 5min after A group being heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C.
(2) dissolve for subsequent use by component C appropriate amount of deionized water, described deionized water consumption is: can make the consumption that cell growth factor and micromolecule victory peptide and/or natural plant extracts are just dissolved;
(3) component C is added in component A, stir 3min and make it even.
(4) mixed solution B component of prior mixed dissolution being added above-mentioned two components stirs and get final product.
Embodiment 3 skin repair essence lotion.
Component and the relative content of the product of composition essence lotion are:
Preparation method:
(1) stir 5min after A group being heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C;
(2) dissolve for subsequent use by component C appropriate amount of deionized water, described deionized water consumption is: can make the consumption that cell growth factor and micromolecule victory peptide and/or natural plant extracts are just dissolved;
(3) component C is added in component A, stir 3min and make it even;
(4) mixed solution B component of prior mixed dissolution being added above-mentioned two components stirs and get final product.
Embodiment 4 skin repair emulsion.
Component and the relative content of the product of group emulsion are::
Preparation method:
(1) stir 5min after A group being heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C;
(2) dissolve for subsequent use by component C appropriate amount of deionized water, described deionized water consumption is: can make the consumption that cell growth factor and micromolecule victory peptide and/or natural plant extracts are just dissolved; .
(3) component C is added in component A, stir 3min and make it even;
(4) mixed solution B component of prior mixed dissolution being added above-mentioned two components stirs and get final product.
Measure of merit:
1, anti-corrosive properties test
With reference to the protective system efficiency evaluation method that Americanized cosmetic, toilet articles and essence association (CTFA) are recommended, the anticorrosion single challenge experiment of 28 days by a definite date of the classics recommended with CTFA, result shows, and embodiment 1 to 4 can by test.
2, skin effects experiment
The preparation obtained by embodiment 1 to 4, respectively through 20-55 year 100 personnel 30 days on probation continuously, relative analysis evaluates preparation obtained in the various embodiments described above to the effect of skin.Result shows, compared to not adding Growth of Cells Summing Factor micromolecule victory peptide, or the product with skin repair effect in the market, the preparation of the present embodiment is to the various damages of skin histology, remove skin sore, acne, go the little defect after nevus, change the skin burn that the decortication after skin, rubescent, fruit acid etc. cause, epidermis injury after grinding has good repairing effect, moreover, said preparation also have whitening wrinkle-removing, calm antiallergic, soft skin, crease-resistant, brighten, clearly, defying age, radioprotective, prevent and alleviate mottle effect.
Claims (10)
1. be rich in cosmetics or the skin care item preparation of somatomedin, it is characterized in that: main component is cell growth factor, micromolecule victory peptide, water, oils and fats, surfactant, wetting agent, antioxidant, antiseptic.
2. preparation as claimed in claim 1, is characterized in that: described cell growth factor accounts for preparation gross mass 0.0001 ~ 0.001%, and described micromolecule victory peptide accounts for 0.0001 ~ 0.002% of preparation gross mass.
3. preparation as claimed in claim 1 or 2, is characterized in that: described somatomedin comprises the one or more combination thing in keratinocyte growth factor, acid fibroblast growth factor, basic fibroblast growth factor, platelet derived growth factor and epidermal growth factor.
4. preparation as claimed in claim 1, is characterized in that: described somatomedin derives from technique for gene engineering by engineering bacteria fermentation purification gained.
5. preparation as claimed in claim 1, is characterized in that: described micromolecule victory peptide comprises one or more in palmityl tripeptides-1, Matrixyl-3, palmityl tripeptides-5, palmityl six peptide-6, palmityl six peptide-9, acetyl tetrapeptide-5, copper peptide, class N-GEECDCGSPENPCCD.
6. preparation as described in right 1, is characterized in that:
Described oils and fats is one or more in olive oil, castor oil hydrogenated, caprylic/capric triglyceride, Oleum Gossypii semen, soybean oil, Oleum Hippophae, Jojoba oil, squalane, lanonol, cetearyl alcohol, polydimethylsiloxane, PSI, cyclic polysiloxanes, and its consumption is: 1%-10%;
Described surfactant is one or more in polysorbas20, Tween 80, sodium laurate, stearyl alcohol sodium sulfate, polyoxyethylene fatty acid ester, ceteareth-2, ceteareth-21, Phosphoric acid monohexadecyl ester, and its consumption is: 1%-10%;
Described wetting agent is one or more in pyrrolidone sodium carboxylate, chondroitin sulfate, glycerol, propylene glycol, hyaluronate sodium, trimethyl glycine, methylglycine proline, xylitol, anhydro xylitol, xylitol glucoside, and its consumption is: 1%-15%;
Described preparation also comprises pH adjusting agent, and described pH adjusting agent is any one in citric acid-sodium citrate, lactic acid-sodium lactate, and its consumption is: 0.1%-3%;
Described antioxidant is one or more in vitamin C, vitamin E, riboflavin, nicotinic acid, metallothionein, superoxide dismutase and dimethylglycine, and its consumption is: 0.1%-1%;
Described antiseptic is one or more in methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben, dimethyloldimethylhydantoin, diazolidinyl urea, IPBC and iodine propilolic alcohol butyl mephenesin Carbamate, and its consumption is: 0.05%-0.2%;
Described cosmetics or skin care item dosage form are any one in cream, Emulsion, essence lotion, gel and facial film.
7. preparation as described in right 1, is characterized in that: also comprise natural plant extracts in preparation, one or more namely in Radix Glycyrrhizae extract, Radix Pulsatillae extract, Pericarpium Zanthoxyli extract, Flos Hibisci extract, Semen Vitis viniferae extract and chicory root extract.
8. preparation as described in right 1, is characterized in that: described natural plant extracts accounts for 0.01% ~ 10% of described cosmetics or skin care item gross mass.
9. preparation as described in right 1, is characterized in that: described natural plant extracts accounts for 0.1% ~ 5% of described cosmetics or skin care item gross mass.
10. the preparation method of preparation as described in any one of claim 1 to 9, it comprises the following steps:
(1) stir 5min after oils and fats and surfactant being heated to 80 DEG C to be uniformly dissolved, leave standstill and be cooled to 40 DEG C;
(2) by cell growth factor and micromolecule victory peptide and antioxidant and/or natural plant extracts deionized water dissolving for subsequent use, described deionized water consumption is: can make the consumption that cell growth factor and micromolecule victory peptide and antioxidant and/or natural plant extracts are just dissolved;
(3) material in step (2) is added in the material in (1), stir 3min and make it even;
(4) mixed solution added in step (3) after one or several mixed dissolutions in wetting agent, pH adjusting agent, preservative component is stirred and get final product.
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| CN109833266A (en) * | 2019-03-29 | 2019-06-04 | 深圳市富可迪生物科技有限公司 | Cosmetic composition |
| CN111789806A (en) * | 2020-08-20 | 2020-10-20 | 甘肃世邦星达生物科技有限公司 | Skin care agent |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1190580A (en) * | 1998-02-24 | 1998-08-19 | 郑文恺 | Skin protective cosmetics containing cell growth factor |
| CN102406556A (en) * | 2011-11-16 | 2012-04-11 | 无限极（中国）有限公司 | Cosmetic composition favorable for keeping biological activity of epidermal growth factor (EGF) |
| US20130171119A1 (en) * | 2007-07-02 | 2013-07-04 | Jan Marini Skin Research, Inc. | Skin care compositions |
| CN103619415A (en) * | 2010-11-30 | 2014-03-05 | 利普泰股份公司 | Exopolysaccharide for the treatment and/or care of the skin, mucous membranes, hair and/or nails |
| KR20140090755A (en) * | 2013-01-10 | 2014-07-18 | 강원대학교산학협력단 | Composition for wound-healing or inhibiting wrinkle formation on skin |
-
2014
- 2014-11-14 CN CN201410643201.3A patent/CN104856892B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1190580A (en) * | 1998-02-24 | 1998-08-19 | 郑文恺 | Skin protective cosmetics containing cell growth factor |
| US20130171119A1 (en) * | 2007-07-02 | 2013-07-04 | Jan Marini Skin Research, Inc. | Skin care compositions |
| CN103619415A (en) * | 2010-11-30 | 2014-03-05 | 利普泰股份公司 | Exopolysaccharide for the treatment and/or care of the skin, mucous membranes, hair and/or nails |
| CN102406556A (en) * | 2011-11-16 | 2012-04-11 | 无限极（中国）有限公司 | Cosmetic composition favorable for keeping biological activity of epidermal growth factor (EGF) |
| KR20140090755A (en) * | 2013-01-10 | 2014-07-18 | 강원대학교산학협력단 | Composition for wound-healing or inhibiting wrinkle formation on skin |
Non-Patent Citations (3)
| Title |
|---|
| 王建新: "《化妆品植物原料手册》", 30 June 2009 * |
| 董银卯，等: "《化妆品配方设计6步》", 30 September 2009 * |
| 赵丽: "《美容化妆品学》", 31 May 2005 * |
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