CN106511136A - Moisturizing cosmetic additive and preparation method thereof and cosmetics containing moisturizing cosmetic additive - Google Patents
Moisturizing cosmetic additive and preparation method thereof and cosmetics containing moisturizing cosmetic additive Download PDFInfo
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- CN106511136A CN106511136A CN201611207933.3A CN201611207933A CN106511136A CN 106511136 A CN106511136 A CN 106511136A CN 201611207933 A CN201611207933 A CN 201611207933A CN 106511136 A CN106511136 A CN 106511136A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention provides a moisturizing cosmetic additive and a preparation method thereof and cosmetics containing the moisturizing cosmetic additive. The moisturizing cosmetic additive is prepared from, by weight, 0.05%-25% of lubrajel oil, 0.05%-25% of trimethylolpropane triacrylate, 0.05%-15% of xylitylglucoside, 0.05%-15% of saccharide isomerate and 20%-60% of polyhydric alcohols. In the moisturizing cosmetic additive, lubrajel oil, trimethylolpropane triacrylate, xylitylglucoside, saccharide isomerate and polyhydric alcohols can generate a synergistic effect, instant moisturizing and continuous water locking can be achieved, and a good property of adjusting hydrophile-lipophile balance of skin can be achieved.
Description
Technical field
The present invention relates to a kind of moisture-keeping cosmetics additive and preparation method thereof and comprising the moisture-keeping cosmetics additive
Cosmetics, belong to cosmetic field.
Background technology
Skin is the important component part of human body, can either prevent the intrusion of the factors such as the physical chemistry in the external world, can also prevent
The Jing epidermises of sealing point and nutriment are lost in.But, if skin barrier function occurs obstacle, lose can moisture of skin,
And how many water content of skin directly affects the normal physiological function of skin.
Cuticula is the position place of skin barrier and function, most close with skin moisture-keeping relation.In general, skin angle
The water content of matter layer is 20-35%, and skin is fine and smooth, soft and moist glossy, is rich in elasticity, is not likely to produce wrinkle and pigment is heavy
.If the water content of keratoderma is less than 10%, the problems such as skin just occurs dry, the obscure coarse and colour of skin, color spot.
Therefore in daily skin nursing, need to keep the water content of skin, reduce the loss of moisture of skin, so as to maintain skin water oil
Poised state.
At present, moisture-keeping cosmetics are by adding all kinds of different NMFs such as Sodium Hyaluronate, glycine betaine, shitosan, many
Single one or more NMF composition such as first alcohol and plant extraction liquid.In prior art, some moisture-keeping cosmetics are used just
When feel that moistening effect is good, but it is simply simple give skin surface moisturizing, drying can be recovered again at short notice after use, it is impossible to
Long-acting moisturizing；The moistening effect of some moisture-keeping cosmetics is good, but infiltration rate is slow when in use, is sticked with rear dermal sensation greasy, residual
Stay and feel and airtight；The moistening effect of some moisture-keeping cosmetics is good, and infiltration rate is fast, but with rear skin is astringent and inadequate light
Sliding exquisiteness etc..
The content of the invention
Problems to be solved by the invention
The present invention provides a kind of moisture-keeping cosmetics additive and preparation method thereof and comprising the moisture-keeping cosmetics additive
Cosmetics.The moistening effect of the moisture-keeping cosmetics additive of the present invention is good, and skin sense experience index is high, is being effectively improved lacking for skin
While water problems, the effect for moistening skin deeply is reached, so as to repair the barrier function of skin, make skin that healthy shape is presented
State.
For solution to problem
The present invention provides a kind of moisture-keeping cosmetics additive, wherein, with the weight percent of the moisture-keeping cosmetics additive
Than meter, including following components：
Reed fragrant plant oil：0.05-25%；
Trimethylolpropane trimethacrylate：0.05-25%；
Xylitol glucoside：0.05-15%；
Carbohydrate isomer：0.05-15%；
Polyalcohol：20-60%.
Moisture-keeping cosmetics additive of the invention, wherein, with the percentage by weight of the moisture-keeping cosmetics additive
Meter, the addition of the reed fragrant plant oil is 5-20%；The addition of the trimethylolpropane trimethacrylate is 5-20%；It is described
The addition of xylitol glucoside is 3-15%；The addition of the carbohydrate isomer is 4-10%；The polyalcohol
Addition be 35-60%.
Moisture-keeping cosmetics additive of the invention, wherein, the reed fragrant plant is oily, the trimethylolpropane tris acrylic acid
The content ratio of ester, the xylitol glucoside, the carbohydrate isomer and the polyalcohol is (0.8-2):(0.1-
5):(0.1-3):(0.1-3):(1-15), preferably (1-1.5):(0.2-4):(0.2-3):(0.2-2):(1.5-12) it is, more excellent
Elect 1 as:(0.2-4):(0.2-3):(0.2-2):(1.5-12).
Moisture-keeping cosmetics additive of the invention, wherein, the polyalcohol includes 1,3-PD, glycerine, fourth
One or more in glycol, DPG, methyl propanediol or 1,2- pentanediols.
Moisture-keeping cosmetics additive of the invention, wherein, the polyalcohol includes 1,3-PD, glycerine, fourth
One or more in glycol, DPG.
The present invention also provides a kind of preparation method of moisture-keeping cosmetics additive of the invention, wherein, including by institute
The step of stating each component of moisture-keeping cosmetics additive and mix.
The present invention also provides a kind of cosmetics, and which includes moisture-keeping cosmetics additive of the invention.
Cosmetics of the invention, wherein, in terms of the percentage by weight of the cosmetics, the moisture-keeping cosmetics addition
The addition of agent is 1-30%, preferably 4-20%.
Cosmetics of the invention, wherein, the cosmetics include water aqua type cosmetics, emulsion-type cosmetics, creme
Type cosmetics；Preferably water aqua type cosmetics.
Cosmetics of the invention, wherein, the water aqua type cosmetics include：Toner or mask；The emulsion
Type cosmetics include：Moisturizing lotion, facial treatment essence, eye essence, sleep mask, moisturizing curry or mildy wash；The creme type
Cosmetics include cold cream frost or eye cream.
The effect of invention
The moisture-keeping cosmetics additive of the present invention, reed fragrant plant oil, trimethylolpropane trimethacrylate, xylitol glucose
Synergy can be produced between glycosides, carbohydrate isomer, polyalcohol, can not only synergy moisturizing, existing instant moisturizing is again
The effect of water lock can be continued, the performance also with good regulation skin water and oil balance.
Further, moisture-keeping cosmetics additive of the invention can significantly improve the barrier function of skin, and percutaneous skin is inhaled
Without glutinous greasy and residual sense after receipts, moistening and soft for skin is persistently kept, makes skin fine and smooth, bright glossy, manifested skin and be good for
Health state.
Description of the drawings
Change curves of the Fig. 1 for the mean skin hydration rate of 30 experimenters of different time spaced points.
Specific embodiment
The present invention provides a kind of moisture-keeping cosmetics additive, including following components：Reed fragrant plant oil, trimethylolpropane tris propylene
Acid esters, xylitol glucoside, carbohydrate isomer and polyalcohol.
The moisture-keeping cosmetics additive of the present invention, by multiple moisturizing technology, is effectively improved the water shortage problem of skin.It is first
First, by reed fragrant plant oil and trimethylolpropane trimethacrylate in the good instant moisturizing water lock effect of the performance of skin surface,
Skin water and oil balance is adjusted effectively；Secondly, compounding polyalcohol causes skin to nutrition and the more preferable absorption of moisture, so as to depth is grown
Profit skin；Finally, in the presence of xylitol glucoside and carbohydrate isomer, effectively reduce the stream of the percutaneous moisture of skin
Lose, deep layer maintenance skin, strengthen the barrier function of skin, so as to improve skin moisturizing ability so that skin has lasting moisturizing
Effect.
Reed fragrant plant oil in the moisture-keeping cosmetics additive of the present invention, is a kind of low viscosity water insoluble liquid of clear, colorless,
PH value is between 5-7.Depositing due to polyglycerolmethacrylate (Polyglycidyl methacrylate) in reed fragrant plant oil
The cagelike structure of uniqueness can be being formed by hydrogen bond and Van der Waals force with water molecules.Due to containing reed fragrant plant oil, when containing
During the cosmetics contact skin of the moisture-keeping cosmetics additive of the present invention, due to the presence of skin surface salt, pH changes, and
And skin temperature change and mechanical friction cause the slow destruction of cagelike structure, make water release, so that skin has light
Pool, and being capable of moisturizing.Reed fragrant plant oil can be used as water-soluble skin emollients, by increasing capacitance it is possible to increase the skin sense of cosmetics and lubricity,
Make it have stronger water lock ability.And the security of reed fragrant plant oil is good, or a kind of wettability equilibrium agent.
Moisture-keeping cosmetics additive of the invention, in terms of the percentage by weight of the moisture-keeping cosmetics additive, institute
The addition for stating reed fragrant plant oil is 0.05-25%, preferably 5-20%.When the addition of reed fragrant plant oil is in 0.05-25%, can be effective
Improve the performance of keeping humidity of moisture-keeping cosmetics additive so that cosmetics have the effect of instant moisturizing and lubrication sense when in use.
Trimethylolpropane trimethacrylate (Trimethylol- in the moisture-keeping cosmetics additive of the present invention
Propane triacrylate), it is a kind of water-soluble grease without greasy feeling, enables to the moisturizing containing the present invention and make up
The cosmetics of product additive have extraordinary gas permeability, hydrophily and wettability.Trimethylolpropane trimethacrylate is simultaneously
With good spreadability, flexibility, permeability, heat-resisting quantity and compatibility with skin so that cosmetics have clear and rich
Skin sense.Cosmetics containing trimethylolpropane trimethacrylate can form the height of similar skin lipid in skin surface
The lamellar gel liquid crystal structure of ordering, being capable of skin care so that skin smooth and softness are soft, with good ridging resistance
With the effect for tightening up skin, skin water and oil balance is adjusted, so as to embody the healthy glow of skin.
Moisture-keeping cosmetics additive of the invention, in terms of the percentage by weight of the moisture-keeping cosmetics additive, institute
The addition for stating trimethylolpropane trimethacrylate is 0.05-25%, preferably 5-20%.When trimethylolpropane tris propylene
The addition of acid esters helps skin to keep water and oil balance in 0.05-25% while can strengthening skin water lock moisture-keeping functions
State.
Xylitol glucoside in the moisture-keeping cosmetics additive of the present invention, by Xylitol-based glucoside, dehydration wood sugar
Alcohol and xylitol composition, from natural plants, can make moisture-keeping cosmetics additive of the present invention promote the transparent of dermis of skin
Matter acid and the increase of chondroitin sulfate, improve the moisture of epidermis, reduce the loss of the percutaneous moisture of skin, improve epiderm skin
Ceramide levels, strengthen skin barrier action, so as to improve the roughness of skin so that skin surface is more smooth.
Moisture-keeping cosmetics additive of the invention, in terms of the percentage by weight of the moisture-keeping cosmetics additive, institute
The addition for stating xylitol glucoside is 0.05-15%, preferably 3-15%.When the addition of xylitol glucoside exists
During 0.05-15%, skin surface moisture can be effectively improved, while lasting moisturizing, can improve and strengthen skin
Barrier function.
Carbohydrate isomer (Pentavitin) in the moisture-keeping cosmetics additive of the present invention, from vegetalitas D-
Glucose, containing compositions such as glucose, fructose, mannose, galactolipin, psicoses.Add carbohydrate isomer carry
The expression of high loricrin (Loricrin) gene, affects the function of hornification coating；Acid sphingomyelins can also be improved
Enzyme gene expression level, stimulates the synthesis of ceramide；The gene expression of a polyprotein and hyaluronic acid synthase 3 can be improved
Level, promotes the combination of NMF NMF and hyaluronic acid, so as to improve skin moisturizing ability.
Further, since the carbonyl in the sugared structure of carbohydrate isomer is combined with the amino in skin keratin, make
Carbohydrate isomer is closely coupled with keratin, is difficult to be washed off, and is only gone in the keratoderma Shi Caihui that comes off naturally
Remove, so that carbohydrate isomer can enduringly play the function of depth water lock and water conservation, so as to persistently improve skin
Roughness, slows down the skin irritatin because cutin comes off or external environment causes and discomfort.
Moisture-keeping cosmetics additive of the invention, in terms of the percentage by weight of the moisture-keeping cosmetics additive, institute
The addition for stating carbohydrate isomer is 0.05-15%, preferably 4-10%.When the addition of carbohydrate isomer exists
When between 0.05-15%, while cosmetics replenishing water and preserving moisture can be made, additionally it is possible to be effectively improved skin pattern, keep skin
Good moist degree.
Polyalcohol in the moisture-keeping cosmetics additive of the present invention, carries out moisturizing using the hydrophily and hygroscopicity of hydroxyl,
Which is safe, it is easy to obtain, and is prevented from the loss of keratoderma moisture, and can be in absorption air moisture, so as to
Realize skin care.
Moisture-keeping cosmetics additive of the invention, in terms of the percentage by weight of the moisture-keeping cosmetics additive, institute
The addition for stating polyalcohol is 20-60%, preferably 35-60%.When the addition of polyalcohol is between 20-60%, preferred 35-
When between 60%, which contributes to the dispersion and dissolving of other components in cosmetics, promotes skin to nutrition and the absorption of moisture, from
And preferably maintain the moist degree of skin.
Moisture-keeping cosmetics additive of the invention, the polyalcohol include 1,3-PD, glycerine, butanediol,
One or more in DPG, methyl propanediol or 1,2- pentanediols.Wherein, 1,3-PD is natural products,
Skin irritatin or allergy will not be caused, product performance of keeping humidity can be strengthened.Glycerine has strong hygroscopicity, can allow on skin
The speed that distributes of moisture slows down, and suitably can absorb water from air.Butanediol is small molecule moisturizing ingredient.Dipropyl two
Alcohol is the NMF little to skin irritation.Methyl propanediol has good moistening effect, while providing salubrious skin sense.1,2-
Pentanediol is good NMF, additionally it is possible to so that preservative usage amount is reduced in cosmetics, and effectively reduce protective system
Excitant, be suitable for the nursing of sensitive tender and lovely skin and aging dry skin.
Preferably, the polyalcohol includes one or two in 1,3-PD, glycerine, butanediol, DPG
More than.
Moisture-keeping cosmetics additive of the invention, wherein, the reed fragrant plant is oily, the trimethylolpropane tris acrylic acid
The content ratio of ester, the xylitol glucoside, the carbohydrate isomer and the polyalcohol is (0.8-2):(0.1-
5):(0.1-3):(0.1-3):(1-15), preferably (1-1.5):(0.2-4):(0.2-3):(0.2-2):(1.5-12) it is, more excellent
Elect 1 as:(0.2-4):(0.2-3):(0.2-2):(1.5-12).
When the reed fragrant plant is oily, the trimethylolpropane trimethacrylate, the xylitol glucoside, the carbohydrate it is same
The content ratio of enantiomers and the polyalcohol is at (0.8-2):(0.1-5):(0.1-3):(0.1-3):(1-15) when between,
Moisturizing synergy can more effectively be realized so that skin can moisturizing immediately and lasting water lock, also with more preferable adjuster
The performance of skin water and oil balance.
Reed fragrant plant oil, trimethylolpropane trimethacrylate, xylitol glucose in the moisture-keeping cosmetics additive of the present invention
Synergy can be produced between glycosides, carbohydrate isomer, polyalcohol, moisturizing synergy can be realized so that skin can reach
To instant moisturizing and the effect of lasting water lock, the performance also with good regulation skin water and oil balance.
Guarantor's cosmetic additive agent of the present invention is applied in cosmetics, can significantly improve the barrier function of skin, percutaneously
After skin absorbs, nothing sticks greasy and residual sense, and persistently holding skin is moist and soft, makes skin fine and smooth, bright glossy, manifests flesh
Skin health status.
In addition, the moisture-keeping cosmetics additive of the present invention is easily prepared, and storage process can add preservative.
The present invention also provides a kind of preparation method of moisture-keeping cosmetics additive of the invention, including by the moisturizing
The step of each component of cosmetic additive agent mixes.Successively according to polyalcohol, reed fragrant plant oil, trimethylolpropane trimethacrylate,
Xylitol glucoside and carbohydrate isomer order are added into clean reactor, after stirring at low speed is mixed at normal temperatures i.e.
Can be directly added in cosmetics.Prepare it is convenient and simple, while can the closed storage under normal temperature, storage process need not add anti-corrosion
Agent.
The present invention also provides a kind of cosmetics, and which includes moisture-keeping cosmetics additive of the invention.
Cosmetics of the invention, wherein, in terms of the percentage by weight of the cosmetics, the moisture-keeping cosmetics addition
Agent addition is 1-30%, preferably 4-20%.When the addition of moisture-keeping cosmetics additive is between 1-30%, preferred 4-
When between 20%, which is more gentle non-stimulated, and the effect with instant moisturizing, rapid glabrous skin.Can moisturizing water lock, together
When can also significantly improve the barrier function of skin, percutaneous skin absorb after without glutinous greasy and residual sense, persistently keep skin moisten and
Softness, makes skin fine and smooth, bright glossy, shows skin health state.
Cosmetics of the invention, the cosmetics include that water aqua type cosmetics, emulsion-type cosmetics, creme type are made up
Product；Preferably water aqua type cosmetics.
Cosmetics of the invention, wherein, the water aqua type cosmetics include：Toner or mask liquid；The breast
Formulation cosmetics include：Moisturizing lotion, facial treatment essence, eye essence, sleep mask, moisturizing curry or mildy wash；The creme
Type cosmetics include cold cream frost or eye cream.
In the present invention, the test of moisture content of skin can adopt Corneometer CM825 instruments, use sample by measurement
Before and after product, the change of keratoderma capacitance to be weighing the change of water content of stratum corneum, so as to evaluating sample moisture-keeping efficacy,
This method is to carry out quantification to keratoderma moisture, being capable of the sensitive change for intuitively reacting skin moisture content
Situation.
In the present invention, the test of skin oil and fat content can adopt MPA580 skin oil and fat content measuring instrument, by measurement
The water and oil balance situation of skin is weighed using the change of skin oil and fat content before and after sample.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.It is unreceipted concrete in embodiment
Condition person, the condition advised according to normal condition or manufacturer are carried out.Agents useful for same or the unreceipted production firm person of instrument, are
The conventional products that commercially available purchase is obtained can be passed through.Reed fragrant plant oil in embodiment is purchased from Ya Shilan companies of the U.S., same point of carbohydrate
Isomers is purchased from dutch royal DSM company.
Embodiment 1
Take reed fragrant plant 16 weight portions of oil, 12 weight portion of trimethylolpropane trimethacrylate, 8 weight of xylitol glucoside
Part, 4 weight portion of carbohydrate isomer, 60 weight portion of glycerine, wherein, reed fragrant plant oil, trimethylolpropane trimethacrylate, wood
Sugar alcohol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:0.75:0.5:0.25:3.75.By above-mentioned each component
After stirring, moisture-keeping cosmetics additive I is obtained.
Embodiment 2
Take reed fragrant plant 20 weight portions of oil, 10 weight portion of trimethylolpropane trimethacrylate, 5 weight of xylitol glucoside
Part, 5 weight portion of carbohydrate isomer, 40 weight portion of butanediol, 20 weight portion of DPG, wherein, reed fragrant plant oil, trihydroxy methyl
Propane triacrylate, xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:0.5:0.25:0.25:
3.After above-mentioned each component is stirred, moisture-keeping cosmetics additive II is obtained.
Embodiment 3
Take reed fragrant plant oil 5 weight portions, 20 weight portion of trimethylolpropane trimethacrylate, 5 weight portion of xylitol glucoside,
10 weight portion of carbohydrate isomer, 30 weight portion of butanediol, 30 weight portion of DPG, wherein, reed fragrant plant oil, trihydroxy methyl third
Alkane triacrylate, xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:4:1:2:12.Will be above-mentioned
After each component stirs, moisture-keeping cosmetics additive III is obtained.
Embodiment 4
Take reed fragrant plant 10 weight portions of oil, 25 weight portion of trimethylolpropane trimethacrylate, 15 weight of xylitol glucoside
Part, 15 weight portion of carbohydrate isomer, 35 weight portion of 1,3-PD, wherein, reed fragrant plant oil, trimethylolpropane tris acrylic acid
Ester, xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:2.5:1.5:1.5:3.5.By above-mentioned each group
Divide after stirring, obtain moisture-keeping cosmetics additive IV.
Embodiment 5
Take reed fragrant plant 6 weight portions of oil, 18 weight portion of trimethylolpropane trimethacrylate, 12 weight of xylitol glucoside
Part, 9 weight portion of carbohydrate isomer, 55 weight portion of methyl propanediol, wherein, reed fragrant plant oil, trimethylolpropane tris acrylic acid
Ester, xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:3:2:1.5:55/6.By above-mentioned each component
After stirring, moisture-keeping cosmetics additive V is obtained.
Embodiment 6
Take reed fragrant plant 12 weight portions of oil, 12 weight portion of trimethylolpropane trimethacrylate, 12 weight of xylitol glucoside
Part, 12 weight portion of carbohydrate isomer, 20 weight portion of glycerine, 32 weight portion of butanediol, wherein, reed fragrant plant oil, trihydroxy methyl
Propane triacrylate, xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:1:1:1:13/3.Will
After above-mentioned each component stirs, moisture-keeping cosmetics additive VI is obtained.
Embodiment 7
Take reed fragrant plant 5 weight portions of oil, 20 weight portion of trimethylolpropane trimethacrylate, 15 weight of xylitol glucoside
Part, 5 weight portion of carbohydrate isomer, 1,2- pentanediols, 10 weight portion, 45 weight portion of glycerine, wherein, reed fragrant plant oil, three hydroxyl first
Base propane triacrylate, xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:4:3:1:11.Will
After above-mentioned each component stirs, moisture-keeping cosmetics additive VII is obtained.
Embodiment 8
Take reed fragrant plant 25 weight portions of oil, 5 weight portion of trimethylolpropane trimethacrylate, 15 weight of xylitol glucoside
Part, 15 weight portion of carbohydrate isomer, 40 weight portion of butanediol, wherein, reed fragrant plant oil, trimethylolpropane trimethacrylate,
Xylitol glucoside, carbohydrate isomer, the weight ratio of polyalcohol are 1:0.2:0.6:0.6:1.6.By above-mentioned each component
After stirring, moisture-keeping cosmetics additive VIII is obtained.
Comparative example 1
Take 20 weight portion of trimethylolpropane trimethacrylate, 10 weight portion of xylitol glucoside, carbohydrate isomerism
10 weight portion of body, 40 weight portion of butanediol, 20 weight portion of DPG.After above-mentioned each component is stirred, moisturizing is obtained
Cosmetic additive IX.
Comparative example 2
Take reed fragrant plant 25 weight portions of oil, 15 weight portion of trimethylolpropane trimethacrylate, 40 weight portion of butanediol, dipropyl two
20 weight portion of alcohol.After above-mentioned each component is stirred, moisture-keeping cosmetics additive X is obtained.
Comparative example 3
Take reed fragrant plant 10 weight portions of oil, 15 weight portion of xylitol glucoside, 15 weight portion of carbohydrate isomer, butanediol
30 weight portions, 30 weight portion of DPG.After above-mentioned each component is stirred, moisture-keeping cosmetics additive XI is obtained.
Comparative example 4
Take reed fragrant plant 28 weight portions of oil, 30 weight portion of trimethylolpropane trimethacrylate, 18 weight of xylitol glucoside
Part, 20 weight portion of carbohydrate isomer, 4 weight portion of DPG.After above-mentioned each component is stirred, moisturizing cosmetic is obtained
Product additive XII.
Comparative example 5
Take reed fragrant plant 10 weight portions of oil, double 25 weight portions of PEG-18 methyl polyether silicone, 15 weight of xylitol glucoside
After above-mentioned each component is stirred by part, 15 weight portion of carbohydrate isomer, 35 weight portion of 1,3-PD, moisturizing is obtained
Cosmetic additive XIII.
<Moisture content of skin is tested>
The moisture-keeping cosmetics addition that moisture-keeping cosmetics additive I that embodiment 1 is prepared, comparative example 2 are prepared
Moisture-keeping cosmetics additive XI that agent X, comparative example 3 are prepared, the reed fragrant plant oil of one-component, trimethylolpropane tris acrylic acid
Ester, xylitol glucoside, carbohydrate isomer, glycerine are dissolved in deionized water respectively, respectively obtain 4% it is water-soluble
Liquid.
Randomly select 30 tested volunteers, the wherein male sex 15, women 15.Experimenter elder generation wash hands forearm,
Sit quietly under constant wet temp (25 DEG C, RH43%) environment 30min, then using experimenter's left and right arm both sides subregion as right
According to each region is 3cm × 3cm, smears the sample of phase homogenous quantities 30mg to fully absorbing, with Corneometer CM825 instrument
Device tests the moisture of corresponding Test sites, and experimental data is repeated 8 times respectively, draws the mean value of each test, records number
According to, then 30 volunteers are calculated in different time spaced points 0h, 0.25h, the average skin of 0.5h, 1h, 3h, 6h, 8h and 12h
Skin hydration rate, the moisture-keeping cosmetics that moisture-keeping cosmetics additive I that comparing embodiment 1 is prepared, comparative example 2 are prepared add
Plus agent X, comparative example 3 prepare moisture-keeping cosmetics additive XI, one-component reed fragrant plant oil, trimethylolpropane tris propylene
The skin hydration effect of 4% aqueous solution of acid esters, xylitol glucoside, carbohydrate isomer and glycerine.
Skin hydration rate is calculated using below equation, and then calculates the mean skin of different time 30 experimenters of spaced points
Hydration rate, it is as a result as shown in table 1 below：
The mean skin hydration rate (%) of 1 30 experimenters of different time spaced points of table
Change curves of the Fig. 1 for the mean skin hydration rate of 30 experimenters of different time spaced points.
Can be seen that under same test concentration by table 1 and Fig. 1, the moisture-keeping cosmetics that the embodiment of the present invention 1 is prepared add
Plus the moistening effect of agent I compares reed fragrant plant oil, trimethylolpropane trimethacrylate, xylitol glucoside, carbohydrate isomerism
Body, the one-component of glycerine moistening effect it is more preferable；Increase over time, reed fragrant plant oil, trimethylolpropane tris acrylic acid
Ester, xylitol glucoside, carbohydrate isomer, the percutaneous water loss amount of the one-component of glycerine compare moisturizing cosmetic
The percutaneous water loss amount of product additive I is high.
The moistening effect of the moisture-keeping cosmetics additive I that the embodiment of the present invention 1 is prepared can be seen that by table 1 and Fig. 1
The moistening effect for comparing moisture-keeping cosmetics additive X and XI that comparative example 2 and comparative example 3 are prepared is more preferable；Over time
Increase, the moistening effect and percutaneous water loss amount of the moisture-keeping cosmetics additive I that the embodiment of the present invention 1 is prepared is less than right
Moisture-keeping cosmetics additive X and XI that ratio 2 and comparative example 3 are prepared.
Therefore, the performance of keeping humidity of moisture-keeping cosmetics additive I of the invention and lasting water lock performance are substantially better than comparative example 2
The moisture-keeping cosmetics additive X and XI prepared with comparative example 3 and the reed fragrant plant oil of one-component, trimethylolpropane tris third
Olefin(e) acid ester, xylitol glucoside, carbohydrate isomer and glycerine.It can be seen that, by by reed fragrant plant oil, trimethylolpropane tris
It is used in conjunction with each other between acrylate, xylitol glucoside, carbohydrate isomer and polyalcohol, with splendid association
With synergy moisture-keeping function, instant moisturizing can be reached and continue the effect of water lock.
In addition, the moisture-keeping cosmetics additive II-VIII that embodiments of the invention 2-8 is prepared also has instant moisturizing
With the effect of lasting water lock.
<Skin oil and fat content measuring>
Moisture-keeping cosmetics additive II, IV and XIII that embodiment 2, embodiment 4 and comparative example 5 are prepared is dissolved in
In ionized water, 12% aqueous solution is respectively obtained.
Skin health is chosen, the experimenter without skin disease and allergies 30 is randomly divided into two groups, every group of experimenter is 15
Name.First group：Carried out with clear water after cleaning dries, the moisture-keeping cosmetics additive II that embodiment 2 is prepared is by 1.8mg/
cm2Tested region is applied in absorbing, while using deionized water as control.Second group：Carried out with clear water after cleaning dries, will
Moisture-keeping cosmetics the additive IV and XIII that embodiment 4 and comparative example 5 are prepared is by 1.8mg/cm2It is applied in tested region extremely
Absorb.By experimenter face zoning, corresponding control of the left and right face for test sample, to choose and symmetric points are taken at forehead and the wing of nose
As test point.Using MPA580 skin oils tester test respectively tested region 0h, 0.5h, 1.5h, 4h and 8h it is each when
The fat content of intermediate node skin, and calculate 15 volunteers of each group and contain in the mean skin grease of different time spaced points
Amount, test data result is as shown in table 2 below and table 3.
Mean skin fat content at 2. each time point experimenter forehead of table
Mean skin fat content at 3. each time point experimenter wing of nose of table
As a result after showing moisture-keeping cosmetics the additive II and IV smeared at experimenter's forehead and the wing of nose, at forehead and the wing of nose
Mean skin fat content value be below control sample water and moisture-keeping cosmetics additive XIII.Therefore, moisturizing of the present invention
Cosmetic additive has the performance of good regulation skin water and oil balance.
In addition, moisture-keeping cosmetics additive I, III, V-VIII that embodiments of the invention 1,3,5-8 are prepared also have
There is the performance for adjusting skin water and oil balance.
Application Example 1-2
Final content (number) according to each component of Application Example 1-2 in table 4 below in toner, and moisturizing makes up
The addition of product additive II-III is 10%, while preparing 2 kinds of toners as steps described below.
The preparation process of toner is as follows：
Step one：Will be polyalcohol, reed fragrant plant oil, trimethylolpropane trimethacrylate, xylitol glucoside and carbohydrate same
Enantiomers order is added into clean reactor, after stirring at low speed mixes 20min at normal temperatures, obtains moisture-keeping cosmetics addition
Agent.
Step 2：In the reactor of step one, add xanthans to be allowed to be uniformly dispersed.Deionization is added in reactor
Water, while the EDETATE SODIUM, allantoin, citric acid and the sodium citrate that add advance deionized water to dissolve, are heated to 60 DEG C
Shi Junzhi 2min.Sodium Benzoate and methyl hydroxybenzoate are added, after mixing, 80 DEG C of insulation 20min, cooling water temperature is continuously heating to
To 45 DEG C.The good essence of solubilising and Cremophor RH40 and phenmethylol in advance are added, 10-15min is sufficiently stirred for, is continued drop
To 37 DEG C, 200 mesh filter-cloth filterings prepare toner to temperature.
Comparison study example 1-5
Final content (number) according to each component of Comparison study example 1-5 in table 4 below in toner, and moisturizing makes up
The addition of product additive IX-XIII is 10%, prepares 5 kinds of toners according to the preparation process of Application Example 1-2.
The toner composition of 4 Application Example 1-2 of table and Comparison study example 1-5
Randomly select oily skin, dry skin and sensitiveness skin crowd experimenter each 35, totally 105, average mark
Into 7 groups, 15 per group；Wherein, a toner of per group of use.Sooner or later a sample is respectively used daily, it is continuous to use 1 month
Afterwards, subject feedback's overall merit marking situation is recorded, number is as shown in table 5.Score value is set to 0-5 point：0 point of meaning with thumb down, 1
Expression is divided to cannot be distinguished by, 2 points represent acceptable reluctantly, and 3 points are satisfied with, and 4 points of expressions are felt quite pleased, and 5 points of expressions are especially satisfied with, point
Higher expression experimenter is higher to the sample skin sense and good results degree and preference degree for value.
5 toner applicating evaluating grade form of table
As can be seen from Table 5, when adding the moisture-keeping cosmetics additive II-III of the present invention, Application Example 1-2 makes
It is substantially higher in the number of Comparison study example 1-5 with the good number of overall merit is evaluated, illustrates to use moisture-keeping cosmetics additive
Toner during II-III is substantially more liked by all types of skin quality experimenters.Meanwhile, different skin quality experimenters instant moisturizing,
It is quick it is smooth, continue water lock, non-greasy, noresidue sense, skin is fine and smooth and soft, moisten and spend, gently do not stimulate and improve
In-service evaluation in terms of complexion is fine, obtains the accreditation and approval of experimenter.
, compared with Comparison study example 2, different skin quality experimenters are to instant moisturizing, quick smooth, not oily for Application Example 1
Greasy, skin is fine and smooth and soft and to improve the effect assessment of the skin sense such as complexion more preferable；Application Example 1 and 3 phase of Comparison study example
Than, different skin quality experimenters to it is quick it is smooth, continue water lock, moisten and spend, gently do not stimulate, skin exquisiteness and softness and changing
The effect assessment of the skin sense such as kind complexion is substantially more preferable.Application Example 2 compared with Comparison study example 4, different skin quality experimenters couple
The effect assessment of the skin sense of moisturizing and non-greasy etc. immediately is substantially more preferable.Application Example 1-2 is compared with Comparison study example 5, different
Skin quality experimenter is substantially more preferable to the effect assessment of the skin sense such as non-greasy and noresidue sense.
The overall skin sense effect phase of the toner that Comparison study example 1-5 is prepared be can be seen that from Comparison study example 1-5
It is more poor than the overall skin sense effect that the toner comprising moisture-keeping cosmetics additive II-III of the present invention brings.
In addition, moisture-keeping cosmetics additive I, IV-VIII addition that the embodiment of the present invention 1 and embodiment 4-8 are prepared
During into toner, also possess instant moisturizing, it is quick it is smooth, continue water lock, non-greasy, noresidue sense, moisten and spend, gently not
Stimulation, skin exquisiteness and effect that is soft and improving complexion.
<Preservative efficacy merit rating>
A certain amount of microorganism is added in cosmetics, the pollution condition being likely to occur is simulated, is examined at regular intervals
The quantity of the biological increase and decrease of micrometer, judges the inhibitor effectiveness of product with this.With reference to American Pharmacopeia USP32<51>Once plus bacterium 28
Its experimental test procedures.Moisture-keeping cosmetics additive I, V and VII that embodiment 1,5 and 7 is prepared as test sample,
Evaluate the preservative efficacy ability of moisture-keeping cosmetics additive of the present invention.
Evaluation criterion：1. the 28th day when, contain bacterium or mould ＞ 10 in sample3Cfu/g, the sample can not pass through microorganism
Corrosion-resistant challenge is tested, and shows that the protective system of sample can not effectively act as suppressing the effect of microorganism, and product is in production, storage
Hide and be highly susceptible to using in the pollution of microorganism.2. the 28th day when, contain bacterium or mould in sample 102～103cfu/g
Between, the sample is conditionally tested by challenge, i.e., when protein in product or other animals and plants material compositions are not special
Height, while the hygienic conditions of production meet the requirements, when packing material is not susceptible to secondary pollution, the protective system can be used, no
Then can not.3. the 28th day when, contain bacterium or mould in sample 10～102Between cfu/g, show the protective system pair of the sample
Microorganism has stronger suppression to kill effect, by challenging test, product production, storage and using when to be not readily susceptible to microorganism dirty
Dye.4., from the 7th day, the bacterium or mould ＜ 10cfu/g in sample illustrates that the protective system of the sample has extra-heavy to microorganism
Inhibitory or killing effect, by challenge test, product production, storage and using when be not easy very much microbial contamination.
Strain subject：Purchased from Guangdong Microbes Inst.
Bacterium：Staphylococcus aureus (Staphylococcus aureus)：ATCC6538
Escherichia coli (Escherchia coli)：ATCC8739
Pseudomonas aeruginosa (Pseudomonas aeruginosa)：ATCC9027
Fungi：Aspergillus niger (Aspergillus niger)：ATCC16404
Candida albicans (Candida albicans)：ATCC10231
Each bacterium is seeded to into nutrient agar slopes respectively, 18～24h is cultivated in 37 DEG C of constant incubators, concentration is produced
For 1.0～5.0 × 108The bacterium bacteria suspension of cfu/mL is standby.Aspergillus niger and Candida albicans are seeded to into PDA culture medium oblique
Face, cultivates 72～96h and 24～48h in 28 DEG C of constant incubators respectively, makes 1.0～5.0 × 107The fungi bacterium of cfu/mL
Suspension is standby.Moisture-keeping cosmetics additive I, V and VII that 100g above-described embodiments 1,5 and 7 prepare are weighed respectively as survey
Test agent, loads in aseptic plastic bottle, adds bacteria suspension in sample, makes bacterium and fungi bacteria containing amount final concentration in sample exist
105～106Between cfu/g, will connect bacterium sample in 22.5 ± 2.5 DEG C place, at the 0th, the 1st day, the 3rd day, the 7th day, the 14th
My god, the 21st day and the 28th day sample, carry out bacterium in lecithin Tween-80 nutrient agar and rose bengal medium culture
Fall to counting, analysis judges the preservative efficacy ability of the product.
The antiseptic power test result of moisture-keeping cosmetics additive I, V and VII of 6 embodiment 1,5 and 7 of table
As can be seen from Table 6, moisture-keeping cosmetics additive I, V and VII that embodiment 1,5 and 7 is prepared is to microorganism
Have stronger preservative efficacy ability, production, storage and using when be not readily susceptible to microorganism pollution, that is, store process without the need for mend
Adding preservative agent.
In addition, moisture-keeping cosmetics additive II-IV, VI and VIII that embodiments of the invention 2-4,6,8 prepare
There is stronger preservative efficacy ability to microorganism.
In sum, application of the moisture-keeping cosmetics additive of the present invention in cosmetics, is adapted to all kinds of skin quality crowds and uses,
It is gentle non-stimulated, and the effect with instant moisturizing, rapid glabrous skin.Can moisturizing water lock, while can also significantly improve skin
The barrier function of skin, percutaneous skin absorb after without glutinous greasy and residual sense, persistently keep moistening and soft for skin, make skin it is fine and smooth,
It is bright glossy, show skin health state.The moisture-keeping cosmetics additive is easily prepared simultaneously, and storage process can not be mended
Adding preservative agent.
Claims (10)
1. a kind of moisture-keeping cosmetics additive, it is characterised in that in terms of the percentage by weight of the moisture-keeping cosmetics additive, bag
Include following components：
Reed fragrant plant oil：0.05-25%；
Trimethylolpropane trimethacrylate：0.05-25%；
Xylitol glucoside：0.05-15%；
Carbohydrate isomer：0.05-15%；
Polyalcohol：20-60%.
2. moisture-keeping cosmetics additive according to claim 1, it is characterised in that with the moisture-keeping cosmetics additive
Percentage by weight meter, the addition of the reed fragrant plant oil is 5-20%；The addition of the trimethylolpropane trimethacrylate is
5-20%；The addition of the xylitol glucoside is 3-15%；The addition of the carbohydrate isomer is 4-10%；
The addition of the polyalcohol is 35-60%.
3. moisture-keeping cosmetics additive according to claim 1 and 2, it is characterised in that the reed fragrant plant is oily, the three hydroxyls first
The content ratio of base propane triacrylate, the xylitol glucoside, the carbohydrate isomer and the polyalcohol
For (0.8-2):(0.1-5):(0.1-3):(0.1-3):(1-15), preferably (1.0-1.5):(0.2-4):(0.2-3):
(0.2-2):(1.5-12), more preferably 1:(0.2-4):(0.2-3):(0.2-2):(1.5-12).
4. the moisture-keeping cosmetics additive according to any one of claim 1-3, it is characterised in that the polyalcohol includes 1,
One or more in ammediol, glycerine, butanediol, DPG, methyl propanediol, 1,2- pentanediols.
5. moisture-keeping cosmetics additive according to claim 4, it is characterised in that the polyalcohol includes 1,3- the third two
One or more in alcohol, glycerine, butanediol, DPG.
6. a kind of preparation method of the moisture-keeping cosmetics additive according to any one of claim 1-5, it is characterised in that bag
Include the step of each component of the moisture-keeping cosmetics additive is mixed.
7. a kind of cosmetics, it is characterised in that include the moisture-keeping cosmetics additive according to any one of claim 1-5.
8. cosmetics according to claim 7, it is characterised in that in terms of the percentage by weight of the cosmetics, the guarantor
The addition of wet cosmetic additive agent is 1-30%, preferably 4-20%.
9. cosmetics according to claim 7 or 8, it is characterised in that the cosmetics include water aqua type cosmetics, emulsion
Type cosmetics, creme type cosmetics；Preferably water aqua type cosmetics.
10. cosmetics according to claim 9, it is characterised in that the water aqua type cosmetics include：Toner or face patch
Film liquid；The emulsion-type cosmetics include：Moisturizing lotion, facial treatment essence, eye essence, sleep mask, moisturizing curry or face cleaning
Breast；The creme type cosmetics include cold cream frost or eye cream.
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| CN109125191A (en) * | 2018-11-03 | 2019-01-04 | 江苏贝塔仕生物科技有限公司 | A kind of cosmetic additive agent that moistening effect is good |
| CN110101591A (en) * | 2019-05-23 | 2019-08-09 | 广州科斯曼生物科技有限公司 | A kind of long-acting moisture-keeping composition and its preparation method and application |
| CN111135105A (en) * | 2020-01-19 | 2020-05-12 | 荆门市诺维英新材料科技有限公司 | Skin care product and preparation method thereof |
| CN112245324A (en) * | 2020-10-29 | 2021-01-22 | 北京瀚梅生物科技有限公司 | Cosmetic with moisturizing function and preparation method and application thereof |
| CN112716832A (en) * | 2020-11-30 | 2021-04-30 | 唐芳艳 | Antistatic skin care product and preparation method thereof |
| CN115645350A (en) * | 2022-11-18 | 2023-01-31 | 皓雨(广州)化妆品制造有限公司 | Skin care product for improving skin and moisturizing skin and preparation method thereof |
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| CN112245324A (en) * | 2020-10-29 | 2021-01-22 | 北京瀚梅生物科技有限公司 | Cosmetic with moisturizing function and preparation method and application thereof |
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