CN109674682A - A kind of cosmetic formulations and preparation method thereof rich in Porcine HGF - Google Patents
A kind of cosmetic formulations and preparation method thereof rich in Porcine HGF Download PDFInfo
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- CN109674682A CN109674682A CN201910045438.4A CN201910045438A CN109674682A CN 109674682 A CN109674682 A CN 109674682A CN 201910045438 A CN201910045438 A CN 201910045438A CN 109674682 A CN109674682 A CN 109674682A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of cosmetic formulations rich in Porcine HGF, including consisting of ingredient: STP0.01~0.2%, Porcine HGF 0.01~0.1%, fish oil 1~10%, surfactant 1~10%, moisturizer 1~15%, antioxidant 0.1~1%, pH adjusting agent 0.1~3%, emulsifier 3%~5%, natural plant extracts 0.1~5% and deionized water;The invention proposes a kind of cosmetic formulations rich in Porcine HGF, the cell of aging can be constantly replaced with new cell, therefore percutaneous update generates wrinkle resistant, anti-wrinkle effect;It can prevent wrinkle of skin, drying, sagging, aging, light injury, or improve skin texture, the flatness of skin;The emulsifying effectiveness that can reinforce cosmetics improves the stability of cosmetics;Easy to operate the invention also provides a kind of preparation method of cosmetic formulations rich in Porcine HGF, required material is simple and easy to get, and cost is relatively low, is worthy to be popularized.
Description
Technical field
The present invention relates to cosmetic formulations technical field, specially a kind of cosmetic formulations rich in Porcine HGF and
Preparation method.
Background technique
Cosmetics refer to any position that human body surface is interspersed among with smearing, sprinkling or other similar method, such as skin
Skin, hair refer to toenail, lips and teeth etc., to reach cleaning, maintenance, beauty, modification and change appearance, or amendment human scent, it protects
Hold the chemical industrial product or fine chemical product for the purpose of kilter.
Cosmetics press effect category: clean type: being used to clearing skin;Skin-protection type: this kind of cosmetics such as cleansing cream is washed one's face
Milk, bath agent, hair-washing hair-care agent, shaving cream etc.;Basic type: before makeup, the based process of opposite size hair, this kind of cosmetics are for example each
Kind face cream, honey, toner, facial mask, hair-cream, hair jelly etc. send out agent surely;Beauty-type: this kind of for face and the beautification articles of hair
Cosmetics refer to kermes, lipstick, eye shadow, the articles such as hair dyeing and perm, hair style processing, fixed;Curative effect-type: between drug and cosmetics it
Between daily chemical product, this kind of cosmetics such as freshener, deodorant educate a mao agent, hair remover, hair dye, pest repellant, olive essence
Deng.The main component biologically active polypeptide of biological skin care item is largely Porcine HGF, and content is atomic in vivo for they, but
Bioactivity is high, plays biological regulation effect to various kinds of cell physiological function and metabolic activity, directly or indirectly influences more
Growth, division, differentiation, proliferation and the migration of seed type cell, in beauty and skin care, plastic surgery, burn ulcer and various skins
It plays an important role in the wound reparation of skin disease and healing.
But the combination of existing cosmetics and Porcine HGF is less.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the existing defects, provides a kind of makeup rich in Porcine HGF
Product preparation and preparation method thereof can effectively solve the problems in background technique.
To achieve the above object, the invention provides the following technical scheme: a kind of cosmetics system rich in Porcine HGF
Agent, including consisting of ingredient: STP0.01~0.2%, Porcine HGF 0.01~0.1%, fish oil 1~10%, surface are living
Property agent 1~10%, moisturizer 1~15%, antioxidant 0.1~1%, pH adjusting agent 0.1~3%, emulsifier 3%~5%, day
Right plant extracts 0.1~5% and deionized water.
As a preferred technical solution of the present invention, a kind of cosmetic formulations rich in Porcine HGF, including with
Lower constituent: STP0.05~0.1%, Porcine HGF 0.01~0.1%, fish oil 2~5%, surfactant 2~
5%, moisturizer 3~10%, antioxidant 0.5~1%, pH adjusting agent 1~3%, emulsifier 3.5%~4.5%, natural plants
Extract 2~4% and deionized water.
As a preferred technical solution of the present invention, a kind of cosmetic formulations rich in Porcine HGF, including with
Lower constituent: STP0.15%, Porcine HGF 0.05%, fish oil 1.5%, surfactant 1.5%, moisturizer 15%,
Antioxidant 0.7%, pH adjusting agent 2%, emulsifier 4%, natural plant extracts 3% and deionized water.
As a preferred technical solution of the present invention, the fish oil includes 45% or more ω -3 polyunsaturated fat
Acid.
As a preferred technical solution of the present invention, the growth factor includes keratinocyte growth factor, fiber finer
One of the intracellular growth factor, platelet derived growth factor and epidermal growth factor or numerous compositions, the fibroblast growth
The factor is basic fibroblast growth factor.
As a preferred technical solution of the present invention, the STP be include palmityl tripeptides -1, Matrixyl -3,
One of palmityl tripeptides -5, palmityl hexapeptide -6, palmityl hexapeptide -9, acetyl tetrapeptide -5, myristoyl pentapeptide -11 are more
Kind compounding.
As a preferred technical solution of the present invention, the surfactant be polysorbas20, Tween 80, sodium laurate,
Stearyl alcohol sodium sulphate, polyoxyethylene fatty acid ester, cetearyl alcohol alcohol ether -2, cetearyl alcohol alcohol ether -21, in Phosphoric acid monohexadecyl ester
One or more compounding;The moisturizer is pyrrolidone sodium carboxylate, chondroitin sulfate, glycerine, propylene glycol, hyaluronic acid
Sodium, methylglycine proline, xylitol, sloughs ionized water xylitol, one in xylitol glucoside at trimethylglycine
Kind or several compoundings.
As a preferred technical solution of the present invention, the pH adjusting agent is citric acid-sodium citrate, lactic acid-lactic acid
Any one or two kinds in sodium are used cooperatively;The emulsifier is glyceryl monostearate, laruyl alcohol sodium sulfovinate, dodecane
One or more of base sodium sulphate compounding.
As a preferred technical solution of the present invention, the natural plant extracts include the composition portion of following parts by weight
Point: 1~4 part of Chinese wolfberry fruit dry cell extract, 2~9 parts of 2~10 part, mao HUOXUEDAN extract of Herba Plantaginis extract, cordyceps sinensis mention
Take 5~15 parts of object.
The invention also provides a kind of preparation methods of cosmetic formulations rich in Porcine HGF, including following step
It is rapid:
S1. the preferably STP of above-mentioned each component, Porcine HGF, fish oil, surfactant, moisturizer, antioxidant,
PH adjusting agent, natural plant extracts and deionized water;
S2. after grease, surfactant and emulsifier being heated to 80 DEG C, at 2000r/min centrifugation to be uniformly mixed,
Standing is cooled to 40 DEG C;
S3. Porcine HGF and STP and antioxidant and/or natural plant extracts is molten with deionization deionized water
Solve spare, the deionized water dosage are as follows: Porcine HGF and STP and antioxidant and/or natural plant extracts can be made
The dosage just dissolved;
S4. the substance in step S3 is added in the substance in S2, stirring 3min makes it uniformly;
S5. the mixing that will be added after one of moisturizer, pH adjusting agent component or several mixed dissolutions in step S4
Solution after mixing evenly, crosses 250 meshes, and adjusting pH value is 5~8, is stirred under vacuum condition, is cooled to 32~37 DEG C, places
20h is dispensed to obtain the final product.
Compared with prior art, the invention proposes a kind of cosmetic formulations rich in Porcine HGF, using STP and
Porcine HGF can reinforce the growth activity of cosmetics and can promote fibroblastic growth and development, constantly with new
Cell replaces the cell of aging, therefore percutaneous update generates wrinkle resistant, anti-wrinkle effect;It is used cooperatively using fish oil,
It can prevent wrinkle of skin, drying, sagging, aging, light injury, or improve skin texture, the flatness of skin;It, can using emulsifier
The emulsifying effectiveness for reinforcing cosmetics, improves the stability of cosmetics;The invention also provides a kind of rich in Porcine HGF
The preparation method of cosmetic formulations, easy to operate, required material is simple and easy to get, and cost is relatively low, is worthy to be popularized.
Specific embodiment
Combined with specific embodiments below the present invention is made further to explain, it is clear that described embodiment is only this hair
Bright a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not having
Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present invention.
Embodiment one
The present invention provides a kind of cosmetic formulations rich in Porcine HGF, including consisting of ingredient:
STP0.08%, Porcine HGF 0.08%, fish oil 4%, surfactant 3%, moisturizer 6%, antioxidant 0.8%, pH
Regulator 2%, emulsifier 4%, natural plant extracts 3% and deionized water, the fish oil are more comprising 45% or more ω -3
Unsaturated fatty acid, the growth factor include keratinocyte growth factor, fibroblast growth factor, platelet derived growth factor
With one of epidermal growth factor or numerous compositions, the fibroblast growth factor be basic fibroblast growth because
Son, the STP be include palmityl tripeptides -1, Matrixyl -3, palmityl tripeptides -5, palmityl hexapeptide -6, palmityl six
One of peptide -9, acetyl tetrapeptide -5, myristoyl pentapeptide -11 or a variety of compoundings, the surfactant are polysorbas20, tween
80, sodium laurate, stearyl alcohol sodium sulphate, polyoxyethylene fatty acid ester, cetearyl alcohol alcohol ether -2, cetearyl alcohol alcohol ether -21, spermaceti
One or more of alcohol phosphate compounding;The moisturizer is pyrrolidone sodium carboxylate, chondroitin sulfate, glycerine, third
Glycol, trimethylglycine, methylglycine proline, xylitol, sloughs ionized water xylitol, xylitol at Sodium Hyaluronate
One or more of glucoside compounding, the pH adjusting agent is citric acid-sodium citrate, any in lactic acid-sodium lactate
One or two are used cooperatively;The emulsifier is glyceryl monostearate, in laruyl alcohol sodium sulfovinate, lauryl sodium sulfate
One or more of compoundings, the natural plant extracts include the component part of following parts by weight: Chinese wolfberry fruit dry cell extract 1
~4 parts, 2~9 parts, 5~15 parts of Cordyceps extract of 2~10 part, mao HUOXUEDAN extract of Herba Plantaginis extract.
Preparation method, comprising the following steps:
S1. the preferably STP of above-mentioned each component, Porcine HGF, fish oil, surfactant, moisturizer, antioxidant,
PH adjusting agent, natural plant extracts and deionized water;
S2. after grease, surfactant and emulsifier being heated to 80 DEG C, at 2000r/min centrifugation to be uniformly mixed,
Standing is cooled to 40 DEG C;
S3. Porcine HGF and STP and antioxidant and/or natural plant extracts is molten with deionization deionized water
Solve spare, the deionized water dosage are as follows: Porcine HGF and STP and antioxidant and/or natural plant extracts can be made
The dosage just dissolved;
S4. the substance in step S3 is added in the substance in S2, stirring 3min makes it uniformly;
S5. the mixing that will be added after one of moisturizer, pH adjusting agent component or several mixed dissolutions in step S4
Solution after mixing evenly, crosses 250 meshes, and adjusting pH value is 5~8, is stirred under vacuum condition, is cooled to 32~37 DEG C, places
20h is dispensed to obtain the final product.
Embodiment two
The present invention provides a kind of cosmetic formulations rich in Porcine HGF, including consisting of ingredient:
STP0.15%, Porcine HGF 0.05%, fish oil 1.5%, surfactant 1.5%, moisturizer 15%, antioxidant
0.7%, pH adjusting agent 2%, emulsifier 4%, natural plant extracts 3% and deionized water, the fish oil include 45% or more
Omega-3 polyunsaturated fatty acids, the growth factor includes keratinocyte growth factor, fibroblast growth factor, blood platelet
One of derivative factor and epidermal growth factor or numerous compositions, the fibroblast growth factor are that basic fibroblast is thin
The intracellular growth factor, the STP be include palmityl tripeptides -1, Matrixyl -3, palmityl tripeptides -5, palmityl hexapeptide -6,
One of palmityl hexapeptide -9, acetyl tetrapeptide -5, myristoyl pentapeptide -11 or a variety of compoundings, the surfactant are to spit
Warm 20, Tween 80, sodium laurate, stearyl alcohol sodium sulphate, polyoxyethylene fatty acid ester, cetearyl alcohol alcohol ether -2, cetostearyl alcohol
One or more of ether -21, Phosphoric acid monohexadecyl ester compounding;The moisturizer be pyrrolidone sodium carboxylate, chondroitin sulfate,
Glycerine, Sodium Hyaluronate, trimethylglycine, methylglycine proline, xylitol, sloughs ionized water xylose at propylene glycol
One or more of alcohol, xylitol glucoside compounding, the pH adjusting agent are citric acid-sodium citrate, lactic acid-sodium lactate
In any one or two kinds be used cooperatively;The emulsifier is glyceryl monostearate, laruyl alcohol sodium sulfovinate, dodecyl
One or more of sodium sulphate compounding, the natural plant extracts include the component part of following parts by weight: Chinese wolfberry fruit dry is thin
1~4 part of born of the same parents' extract, 2~9 parts of 2~10 part, mao HUOXUEDAN extract of Herba Plantaginis extract, Cordyceps extract 5~15
Part.
Preparation method, comprising the following steps:
S1. the preferably STP of above-mentioned each component, Porcine HGF, fish oil, surfactant, moisturizer, antioxidant,
PH adjusting agent, natural plant extracts and deionized water;
S2. after grease, surfactant and emulsifier being heated to 80 DEG C, at 2000r/min centrifugation to be uniformly mixed,
Standing is cooled to 40 DEG C;
S3. Porcine HGF and STP and antioxidant and/or natural plant extracts is molten with deionization deionized water
Solve spare, the deionized water dosage are as follows: Porcine HGF and STP and antioxidant and/or natural plant extracts can be made
The dosage just dissolved;
S4. the substance in step S3 is added in the substance in S2, stirring 3min makes it uniformly;
S5. the mixing that will be added after one of moisturizer, pH adjusting agent component or several mixed dissolutions in step S4
Solution after mixing evenly, crosses 250 meshes, and adjusting pH value is 5~8, is stirred under vacuum condition, is cooled to 32~37 DEG C, places
20h is dispensed to obtain the final product.
The invention proposes a kind of cosmetic formulations rich in Porcine HGF can using STP and Porcine HGF
Reinforce the growth activity of cosmetics and fibroblastic growth and development can be promoted, the thin of aging is constantly replaced with new cell
Born of the same parents, therefore percutaneous update generates wrinkle resistant, anti-wrinkle effect;It is used cooperatively using fish oil, wrinkle of skin can be prevented, done
Dry, sagging, aging, light injury, or improve skin texture, the flatness of skin;Using emulsifier, the emulsification effect of cosmetics can be reinforced
Fruit improves the stability of cosmetics;The invention also provides a kind of preparation sides of cosmetic formulations rich in Porcine HGF
Method, easy to operate, required material is simple and easy to get, and cost is relatively low, is worthy to be popularized.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (10)
1. a kind of cosmetic formulations rich in Porcine HGF, which is characterized in that including consisting of ingredient: STP0.01~
0.2%, Porcine HGF 0.01~0.1%, fish oil 1~10%, surfactant 1~10%, moisturizer 1~15%, anti-
Oxidant 0.1~1%, pH adjusting agent 0.1~3%, emulsifier 3%~5%, natural plant extracts 0.1~5% and deionization
Water.
2. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that including following
Constituent: STP0.05~0.1%, Porcine HGF 0.01~0.1%, fish oil 2~5%, surfactant 2~5%,
Moisturizer 3~10%, antioxidant 0.5~1%, pH adjusting agent 1~3%, emulsifier 3.5%~4.5%, extracted form natural plant
Object 2~4% and deionized water.
3. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that including following
Constituent: STP0.15%, Porcine HGF 0.05%, fish oil 1.5%, surfactant 1.5%, moisturizer 15%, resist
Oxidant 0.7%, pH adjusting agent 2%, emulsifier 4%, natural plant extracts 3% and deionized water.
4. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that the fish oil
Include 45% or more omega-3 polyunsaturated fatty acids.
5. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that the growth
The factor includes one in keratinocyte growth factor, fibroblast growth factor, platelet derived growth factor and epidermal growth factor
Kind or numerous compositions, the fibroblast growth factor are basic fibroblast growth factor.
6. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that the STP
Being includes palmityl tripeptides -1, Matrixyl -3, palmityl tripeptides -5, palmityl hexapeptide -6, palmityl hexapeptide -9, acetyl four
One of peptide -5, myristoyl pentapeptide -11 or a variety of compoundings.
7. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that the surface
Activating agent be polysorbas20, Tween 80, sodium laurate, stearyl alcohol sodium sulphate, polyoxyethylene fatty acid ester, cetearyl alcohol alcohol ether -2,
One or more of cetearyl alcohol alcohol ether -21, Phosphoric acid monohexadecyl ester compounding;The moisturizer be pyrrolidone sodium carboxylate,
Chondroitin sulfate, propylene glycol, Sodium Hyaluronate, trimethylglycine, methylglycine proline, xylitol, is sloughed glycerine
One or more of ionized water xylitol, xylitol glucoside compounding.
8. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that the pH tune
Section agent is that citric acid-sodium citrate, any one or two kinds in lactic acid-sodium lactate are used cooperatively;The emulsifier is glycerol
One or more of monostearate, laruyl alcohol sodium sulfovinate, lauryl sodium sulfate compounding.
9. a kind of cosmetic formulations rich in Porcine HGF according to claim 1, which is characterized in that described natural
Plant extracts includes the component part of following parts by weight: 1~4 part of Chinese wolfberry fruit dry cell extract, Herba Plantaginis extract 2~10
Part, 2~9 parts of hair HUOXUEDAN extract, 5~15 parts of Cordyceps extract.
10. a kind of preparation method of the cosmetic formulations rich in Porcine HGF, it is characterised in that: the following steps are included:
S1. STP, Porcine HGF, fish oil, surfactant, moisturizer, antioxidant, the pH tune of preferred above-mentioned each component
Save agent, natural plant extracts and deionized water;
S2. after grease, surfactant and emulsifier being heated to 80 DEG C, centrifugation is stood to being uniformly mixed at 2000r/min
It is cooled to 40 DEG C;
S3. Porcine HGF and STP and antioxidant and/or natural plant extracts is standby with deionization deionized water dissolving
With the deionized water dosage are as follows: Porcine HGF and STP and antioxidant and/or natural plant extracts can be made just
The dosage of dissolution;
S4. the substance in step S3 is added in the substance in S2, stirring 3min makes it uniformly;
S5. the mixed solution that will be added after one of moisturizer, pH adjusting agent component or several mixed dissolutions in step S4
After mixing evenly, 250 meshes are crossed, adjusting pH value is 5~8, is stirred under vacuum condition, is cooled to 32~37 DEG C, 20h is placed, into
Row dispenses to obtain the final product.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110327277A (en) * | 2019-08-13 | 2019-10-15 | 马悦馨 | A kind of herbal mixture skin care formulation and preparation method thereof rich in growth factor |
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CN104856892A (en) * | 2014-11-14 | 2015-08-26 | 广州远想生物科技有限公司 | Cosmetic or skin care product preparation rich in growth factors and preparation method therefor |
KR20170050633A (en) * | 2015-10-30 | 2017-05-11 | 주식회사 펩트론 | Tripeptide with activities of growth and activation of skin keratinocyte stem cell and use thereof |
CN108030756A (en) * | 2017-12-05 | 2018-05-15 | 广州赛莱拉干细胞科技股份有限公司 | It is a kind of to dispel livid ring around eye skin care item and preparation method thereof containing Chinese wolfberry fruit dry cell extract |
CN108836896A (en) * | 2018-08-20 | 2018-11-20 | 辅必成(上海)医药科技有限公司 | A kind of stable fish oil cream for being used for skin care item and cosmetics |
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2019
- 2019-01-17 CN CN201910045438.4A patent/CN109674682A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104856892A (en) * | 2014-11-14 | 2015-08-26 | 广州远想生物科技有限公司 | Cosmetic or skin care product preparation rich in growth factors and preparation method therefor |
KR20170050633A (en) * | 2015-10-30 | 2017-05-11 | 주식회사 펩트론 | Tripeptide with activities of growth and activation of skin keratinocyte stem cell and use thereof |
CN108030756A (en) * | 2017-12-05 | 2018-05-15 | 广州赛莱拉干细胞科技股份有限公司 | It is a kind of to dispel livid ring around eye skin care item and preparation method thereof containing Chinese wolfberry fruit dry cell extract |
CN108836896A (en) * | 2018-08-20 | 2018-11-20 | 辅必成(上海)医药科技有限公司 | A kind of stable fish oil cream for being used for skin care item and cosmetics |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN110327277A (en) * | 2019-08-13 | 2019-10-15 | 马悦馨 | A kind of herbal mixture skin care formulation and preparation method thereof rich in growth factor |
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Application publication date: 20190426 |