CN105193671B - A kind of nourishing facial treatment milk and preparation method thereof - Google Patents

A kind of nourishing facial treatment milk and preparation method thereof Download PDF

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Publication number
CN105193671B
CN105193671B CN201510713075.9A CN201510713075A CN105193671B CN 105193671 B CN105193671 B CN 105193671B CN 201510713075 A CN201510713075 A CN 201510713075A CN 105193671 B CN105193671 B CN 105193671B
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skin
kind
deg
facial treatment
growth factor
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CN201510713075.9A
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CN105193671A (en
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苏建华
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苏建华
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Abstract

The present invention relates to a kind of nourishing facial treatment milk comprising contains following components by percentage to the quality: Porcine HGF 0.0001-0.001%, black bearberry leaf extract 0.5-5%, glycyrrhetinic acid 1-5%, allantoin 0.1-0.5%, house oil 2-5%, sad Propylheptyl 5-10%, glucose aminoglucan 2-6%, alcohols 6-15%, carbomer 1-3%, diethyl hexylcarbonate 4-6%, surfactant 1-5%, preservative 0.01-1%, pH adjusting agent 0.01-5%, water surplus;Wherein Porcine HGF, black bearberry leaf extract and glycyrrhetinic acid reasonable compatibility, collaboration play the role of skin care, enhancing skin elasticity, reduce pigment deposition, promote cell repair and regenerated, to achieve the purpose that nourish the skin that shines;Invention also provides preparation method, the activity of effective component, the effect that makes it nourish shining skin are more significant in effective protection prescription.

Description

A kind of nourishing facial treatment milk and preparation method thereof

Technical field

The present invention relates to cosmetic technical fields more particularly to a kind of nourishing facial treatment milk and preparation method thereof.

Background technique

With advancing age, skin degenerative, skin, which is difficult to avoid that, will appear some small situations, along with by purple The factors such as irradiation, air pollution, the physical fatigue of outside line, skin can feel burnout, lose moist, cause water oil uneven, flesh Skin drying is coarse, lacks oil, moisture and nutrient necessary to supply skin operates.It nourishes when skin lacks, also can accordingly draw A series of problems, such as playing spot, wrinkle, dark yellow, matt complexion.

Currently, nourishes rough skin cosmetics on the market mainly use mineral oil and some chemical substances to reach nourishing skin The purpose of skin, the problem of being primarily present are that effect is not significant, and long-time service be easy to cause skin to bear, accelerate skin aging and Easily cause allergic phenomena.Therefore, it is good to develop a kind of nourishes effect, also has the function of shining skin, and mild inirritative skin care produces Product are a problem to be solved.

Summary of the invention

The purpose of the present invention provides a kind of nourishing facial treatment milk and preparation method thereof, the nourishing skin care prepared with this method Lotion its not only nourishes effect is good, also have the function of shining skin, and do not stimulate mildly.

To achieve the goals above, the technical solution adopted by the present invention is as follows:

Technical solution one:

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

As further improvement of the invention, the Porcine HGF is selected from keratinocyte growth factor, acidity into fibre Tie up one of Porcine HGF, basic fibroblast growth factor, platelet derived growth factor and epidermal growth factor or It is several;

The alcohols is selected from glycerol, propylene glycol, polyethylene glycol, polypropylene glycol, polytetramethylene glycol -8;Polytetramethylene glycol -5;Poly- fourth One or more of glycol -3;

The surfactant in two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26 one Kind is several;

The pH adjusting agent is selected from one or both of triethanolamine, arginine.

As further improvement of the present invention comprising contain following components by percentage to the quality:

Technical solution two:

A kind of preparation method of nourishing facial treatment milk described in a kind of technical solution one, specifically comprises the following steps:

Step 1: weighing each component by above-mentioned mass percent proportion;

Step 2: house oil is heated to 45 DEG C of thawings, Porcine HGF is then added, it is cooling rapidly after being uniformly dispersed It is solidified to house oil, obtains cell factor-house oil lotion;

Step 3: by sad Propylheptyl, glucose aminoglucan, alcohols, carbomer, diethyl hexylcarbonate, surface Activating agent and water are added in emulsion tank, stir evenly, emulsify 30min after being heated to 80-90 DEG C;It is cooled to 40-50 DEG C, is added anti- Rotten agent, black bearberry leaf extract, glycyrrhetinic acid, allantoin, pH adjusting agent continue after emulsifying 10min, are cooled to≤20 DEG C, then Be added the resulting cell factor of step 2-house oil paste, in≤20 DEG C stirring to be uniformly dispersed to get.

As further improvement of the invention, the water is deionized water.

In the present invention:

Porcine HGF: including acid fibroblast growth factor (AFGF), basic fibroblast growth factor (BFGF), epithelical cell growth factor (EGF), keratinocyte growth factor (KGF-2) and platelet derived growth factor (PDGF) Deng, several factors compounding can promotion skin texture from inside to outside improvement, accelerate skin repair speed, reduce scar and produce It is raw.

Epithelical cell growth factor can stimulate epithelial cell and endothelial cell growth, grow up to new epidermal cell constantly, Dead skin layer is pushed and is gradually fallen off, keeps skin delicacy smooth.Promote the metabolism of the various cells of skin simultaneously, enhancing is thin Born of the same parents absorb nutriment.Promote collagen and collagen enzymatic synthesis, it is fine to adjust collagen for secretion Collagen material, hyaluronic acid and glycoprotein Dimension has and moisturizes the skin, enhances skin elasticity, reduces wrinkle of skin and prevents the effect of skin aging.Have in beauty circle " beautiful The title of the factor ".

Acid fibroblast growth factor is a kind of multifunctional powerful cell factor, to the fibroblastic metabolism of promotion Formation with collagen plays critical function;It can promote the growth and breeding of skin histology, it passes through special with cell surface Receptor combines, and regulates and controls skin epidermis, and division, breeding and the Growth and Differentiation of endothelium and stroma cell promote cell metabolism, enhances oxygen Change effect;Can promote cell related with skin injury mushrooms out breeding, and adjusts the synthesis of intercellular matrix, secretes and divide Solution;It can promote the regeneration of corneocyte, accelerate the reparation of keratoderma and hypothallus, promote the life of human skin cell It is long;The synthesis and cell metabolism of the protein of Skin Cell can be enhanced, with delaying skin cell ageing, promote epidermal cell Reparation and growth, keep skin smooth plump.

Basic fibroblast growth factor is existing a kind of denier cyclin in human body, it can promote more On the one hand the growth and differentiation of kind cell adjust and balance endocrine by the variation of blood vessel, nerve and body fluid, be excited into fibre Tie up the increment of mother cell and promote it is more plain increase and various related substances, such as a variety of amino acid, elastin laminin, collagen Deng increase, maintain the normal function and vigor of skin, make deformation fat cell be restored, vigor enhancing;Its again quilt Referred to as corium growth factor, is primarily present in the keratinocyte of epidermal basal, be important promote cell mitogen because Son and angiogenesis factor, it is living with extensive biology to a plurality of types of cells from mesoderm and neuroderm Property, cell Proliferation, growth, differentiation can be promoted, promote angiogenesis, improve cell life microenvironment, promote injured nerve regeneration And the reparation of blood vessel, muscle, skin etc., it reduces ultraviolet radiation and is damaged caused by skin, be neurotrophic and regeneration The factor has the title of " cell activating agent ".

The growth and breeding of keratinocyte growth factor promotion skin histology;By regulating and controlling in conjunction with specific cell surface receptors The division growth and Growth and Differentiation of skin epidermis, endothelium and stroma cell promote the metabolism of cell, enhance oxidation;Promote With skin injury in relation to the rapid proliferation of cell, and adjusts the synthesis of intercellular matrix (such as collagen) and secrete and divide Solution;To promote the regeneration of corneocyte, accelerate the reparation of keratoderma and basal layer, when tissue cultures, promotes human body Skin epithelial cell growth;Enhance the synthesis and cell metabolism of the protein, RNA of epidermal cell;It declines with delaying skin cell Always, the effect for promoting reparation and the growth of fell cell, keeps skin smooth plump.

Platelet derived growth factor is a kind of important factor,mitogenic, has stimulation specific cells group division growth Ability promotes the generation of fibroblast, to repair the skin corium collagenous fibres fracture as caused by aging and damage and become Shape promotes skin corium growth to be promoted with elasticity, keeps wrinkle naturally long flat.Promote collagen directly to synthesize in skin corium, more has Effect delays senescence.Replenishing collagen is almost the common sense that each people seeking beauty both knows about now.However, how human body to be allowed more to fill The absorption collagen divided is always the topic being difficult to resolve.PDGF can promote the activity of fibroblast and promote secretion collagen Albumen.The collagen for promoting fibroblast to generate by PDGF more can effectively prolong than directly smearing or edible collagen Slow skin aging.Promote subcutaneous capillary to be formed, repairs subcutaneous blood microcirculqtory system, provide sufficient nutrition for skin.Skin One important reason of skin aging is exactly veins beneath the skin atrophy, and so as to cause skin blood supply insufficiency, therefore cell lacks nutrition, causes The generation of wrinkle.Many growth factors participate in the Physiological effect of angiogenesis.Each serves most important wherein.Its The regeneration vessel function of middle PDGF has obvious curative effects for anti-aging.Promote the growth and update of Skin Cell, promotes skin The physiological activity and metabolism of tissue, enhance the immunity and self-repairing capability of Skin Cell, repair due to daylight, Red capillary caused by severe cold, chemical substance and mechanical wear injure and sensitive skin keep Skin Cell more pale moist, fresh and alive It is full, make facial colour spot obscure, the aging of withered and yellow drying assumes an entirely new aspect.

Black bearberry leaf extract: being a kind of depigmentation of skin composition in the leaf cells of Ericaceae black bearberry category black bearberry. Arbutin can effectively inhibit the activity of the biological tyrosinase (Tyrosinase) in skin, block the formation of melanin, pass through Itself is directly binded to tyrosinase, and accelerates the decomposition and excretion of melanin, so that Skin pigmentation is reduced, dispelling stain and sparrow Spot.

Glycyrrhetinic acid: also known as enoxolone, it is classical anti-inflammatory drug, is applied in cosmetics and skin is adjusted Immune function enhances the disease resistance of skin, diminishes inflammation, pre- hypo-allergenic, cleaning skin, while can also release phase in cosmetics Ingredient and other extraneous factors are closed to the toxic side effect of skin.It can also effectively inhibit the activation of tyrosinase, prevent melanin Generation, have whitening skin lightening, antibacterial anti-inflammatory, anti-oxidant, anti-aging, spot-removal function

Allantoin: can promote the outermost water absorbing capacity of skin, and can enhance the hydrophilic power of keratoprotein molecule, therefore energy Increasing the water content in skin tissue makes the dry skin of non-pathological state, coarse, aging, and the symptoms such as long wrinkle are improved.

House oil: room temperature white solid, free from extraneous odour, acid value: < 1.0mgKOH/g, peroxide value: < 3.0meq/kg, saponification Value: 195-199, iodine number: 72-86, melting point (freezing point): 36-43 DEG C, index of refraction (40 DEG C): 1.462, relative density (25 DEG C): 0.90-0.915, unsaturated fatty acid content reach 60% or more, and wherein polyunsaturated fatty acid relative amount is up to 24% More than;Also containing relatively abundant VE and a certain amount of VA;The ingredient of horse fat fat and other animal tallows have obvious difference, contain The active constituent of natural anti-oxidation performance is a kind of good natural;Its with moisturizing and moisten, anti-inflammatory releive, Anti-oxidant, anti-acne, Bearberry Extract.

Sad Propylheptyl: it can provide the soft lubrication skin sense of multidimensional, assign formula unique hand feeling.It is anti-to various crystal types Shining agent has good dissolving power, has good dispersion moistening performance to toner class.

Glucose aminoglucan: can promote blood circulation, and improve cell repair, have good percutaneous absorbability.

Methylisothiazolinone: being a kind of efficient germicide, heat-resisting waterborne preservative, can inhibit bacterium, fungi, mould The growth of the microorganisms such as bacterium and mould.

Alcohols: glycerol, propylene glycol, polyethylene glycol, polypropylene glycol, polytetramethylene glycol -8;Polytetramethylene glycol -5;Polytetramethylene glycol -3 is made For wetting agent, the water of skin can be kept to moisten.

Diethyl hexylcarbonate: be it is a kind of have with extremely low viscosity, high spreadability and to lenticular active matter it is good The very salubrious grease of solubilising.

Carbomer: being a kind of very important rheology control agent, the carbomer after neutralization is outstanding gel-type vehicle, there is increasing The important uses such as thick, suspension.

Compared with prior art, obtained by the present invention to have the beneficial effect that:

1, (keratinocyte growth factor, acidity are at fibre for black bearberry leaf extract, glycyrrhetinic acid and cell factor in the present invention Tie up Porcine HGF, basic fibroblast growth factor, platelet derived growth factor and epidermal growth factor) reasonable compatibility, Collaboration play the role of skin care, enhancing skin elasticity, reduce pigment deposition, promote cell repair with it is regenerated, to reach Delay skin aging, the purpose for nourishing shining skin.

2, due to Porcine HGF under solution state unstable, easy in inactivation, therefore the present invention during the preparation process will Porcine HGF is scattered in house oil, is prepared into cell factor-house oil lotion, is then dispersed the lotion in skin care item, The effective protection activity of cell factor, so that the facial treatment milk of the invention effect in terms of nourishing shining skin is more significant, storage life Also longer.

3, the present invention uses matrix of the house oil as dispersed encapsulated cell factor, the advantage is that, the freezing point of house oil is 36-43 DEG C, usually in refrigerator cold-storage, house oil cell factor can be isolated with other compositions of the skin care because in, in use, by it It is applied to face, at the temperature of human body and massage effect, house oil is easy to melt, to discharge cell factor, and its strong infiltration Property, it is easier to cell factor is brought to the bottom of skin into, to preferably play nourishing, shining skin effect;In addition house oil itself Have the effects that moisturizing and moist, anti-inflammatory releive, are anti-oxidant, plays effect in terms of nourishing shining skin.

Prescription cooperation science in the present invention, natural safety is without side-effects, acts synergistically between each component, effect Xiang Fuxiang At, and in preparation method effective protection prescription effective component activity, growing nourishing facial treatment milk produced by the present invention Shining skin aspect significant effect is supported, while also extending the shelf-life of facial treatment milk.

Specific embodiment

Black bearberry leaf extract: Shaanxi Kang Sheng Bioisystech Co., Ltd

Glycyrrhetinic acid: Shaanxi Sen Fu natural product Co., Ltd

Acid fibroblast growth factor: Xi'an Wei Fulan peptide Biotechnology Co., Ltd

Keratinocyte growth factor: Xi'an Wei Fulan peptide Biotechnology Co., Ltd

Epidermal growth factor: Xi'an Wei Fulan peptide Biotechnology Co., Ltd

Further details of narration is carried out to the present invention with reference to embodiments.

Embodiment 1

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

The preparation method is as follows:

Step 1: weighing each component by above-mentioned mass percent proportion;

Step 2: house oil is heated 45 DEG C of thawings, Porcine HGF (keratinocyte growth factor, acidity is then added Fibroblast growth factor, epithelical cell growth factor), after being uniformly dispersed, be rapidly cooled to house oil solidification, obtain cell because Son-house oil lotion;

Step 3: by sad Propylheptyl, glucose aminoglucan, alcohols (glycerol, propylene glycol, polyethylene glycol), card wave Nurse, diethyl hexylcarbonate, surfactant (two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26) and Deionized water is added in emulsion tank, stirs evenly, emulsifies 30min after being heated to 85 DEG C;45 DEG C are cooled to, preservative (first is added Base isothiazolinone, methyl hydroxybenzoate, butyl hydroxybenzoate, ethyl hydroxy benzoate, oxybenzene isobutyl ester), black bearberry leaf extract, glycyrrhetinic acid, urine Bursin, pH adjusting agent (triethanolamine) continue after emulsifying 10min, are cooled to≤20 DEG C, the resulting cell of step 2 is then added The factor-house oil paste, in≤20 DEG C stirring to be uniformly dispersed to get.

Method for preserving: it is saved in refrigerator cold-storage.

Application method: after daily face cleaning, it is uniformly applied to face in right amount, once in the morning and once at night;

Embodiment 2

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

The preparation method is as follows: with embodiment 1.

Method for preserving: with embodiment 1.

Application method: with embodiment 1.

Embodiment 3

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

The preparation method is as follows: with embodiment 1

Method for preserving: with embodiment 1.

Application method: with embodiment 1.

Comparative example 1

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

Preparation method:

Step 1: weighing each component by above-mentioned mass percent proportion;

Step 2: house oil is heated 45 DEG C of thawings, Porcine HGF (keratinocyte growth factor, acidity is then added Fibroblast growth factor, epithelical cell growth factor), after being uniformly dispersed, be rapidly cooled to house oil solidification, obtain cell because Son-house oil lotion;

Step 3: by sad Propylheptyl, glucose aminoglucan, alcohols (glycerol, propylene glycol, polyethylene glycol), card wave Nurse, diethyl hexylcarbonate, surfactant (two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26) and Deionized water is added in emulsion tank, stirs evenly, emulsifies 30min after being heated to 85 DEG C;45 DEG C are cooled to, preservative (first is added Base isothiazolinone, methyl hydroxybenzoate, butyl hydroxybenzoate, ethyl hydroxy benzoate, oxybenzene isobutyl ester), glycyrrhetinic acid, allantoin, pH adjusting agent (triethanolamine) continues after emulsifying 10min, is cooled to≤20 DEG C, the resulting cell factor-house oil cream of step 2 is then added Agent, in≤20 DEG C stirring to be uniformly dispersed to get.

Method for preserving: with embodiment 1.

Application method: with embodiment 1.

Comparative example 2

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

The preparation method is as follows:

Step 1: weighing each component by above-mentioned mass percent proportion;

Step 2: house oil is heated 45 DEG C of thawings, Porcine HGF (keratinocyte growth factor, acidity is then added Fibroblast growth factor, epithelical cell growth factor), after being uniformly dispersed, be rapidly cooled to house oil solidification, obtain cell because Son-house oil lotion;

Step 3: by sad Propylheptyl, glucose aminoglucan, alcohols (glycerol, propylene glycol, polyethylene glycol), card wave Nurse, diethyl hexylcarbonate, surfactant (two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26) and Deionized water is added in emulsion tank, stirs evenly, emulsifies 30min after being heated to 85 DEG C;45 DEG C are cooled to, preservative (first is added Base isothiazolinone, methyl hydroxybenzoate, butyl hydroxybenzoate, ethyl hydroxy benzoate, oxybenzene isobutyl ester), black bearberry leaf extract, allantoin, pH tune It saves agent (triethanolamine), continues after emulsifying 10min, be cooled to≤20 DEG C, the resulting cell factor-house oil of step 2 is then added Paste, in≤20 DEG C stirring to be uniformly dispersed to get.

Method for preserving: with embodiment 1.

Application method: with embodiment 1.

Comparative example 3

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

The preparation method is as follows:

Step 1: weighing each component by above-mentioned mass percent proportion;

Step 2: house oil is heated 45 DEG C of thawings, it is rapidly cooled to house oil solidification, obtains house oil lotion;

Step 3: by sad Propylheptyl, glucose aminoglucan, alcohols (glycerol, propylene glycol, polyethylene glycol), card wave Nurse, diethyl hexylcarbonate, surfactant (two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26) and Deionized water is added in emulsion tank, stirs evenly, emulsifies 30min after being heated to 85 DEG C;45 DEG C are cooled to, preservative (first is added Base isothiazolinone, methyl hydroxybenzoate, butyl hydroxybenzoate, ethyl hydroxy benzoate, oxybenzene isobutyl ester), black bearberry leaf extract, glycyrrhetinic acid, urine Bursin, pH adjusting agent (triethanolamine) continue after emulsifying 10min, are cooled to≤20 DEG C, house oil lotion be then added, in≤20 DEG C stirring to be uniformly dispersed to get.

Method for preserving: with embodiment 1.

Application method: with embodiment 1.

Comparative example 4

A kind of nourishing facial treatment milk comprising contain following components by percentage to the quality:

The preparation method is as follows:

Step 1: weighing each component by above-mentioned mass percent proportion;

Step 2: by sad Propylheptyl, glucose aminoglucan, alcohols (glycerol, propylene glycol, polyethylene glycol), card wave Nurse, diethyl hexylcarbonate, surfactant (two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26) and Deionized water is added in emulsion tank, stirs evenly, emulsifies 30min after being heated to 85 DEG C;45 DEG C are cooled to, preservative (first is added Base isothiazolinone, methyl hydroxybenzoate, butyl hydroxybenzoate, ethyl hydroxy benzoate, oxybenzene isobutyl ester), black bearberry leaf extract, glycyrrhetinic acid, urine Bursin, pH adjusting agent (triethanolamine), Porcine HGF (keratinocyte growth factor, acid fibroblast growth factor, Epithelical cell growth factor), house oil, continue emulsify 10min after, be cooled to≤20 DEG C to get.

Method for preserving: with embodiment 1.

Application method: with embodiment 1.

Effect example 1

Cosmetics made from above-described embodiment and comparative example are continuously tried out 30 days through 22~50 years old 200 personnel respectively, The nourishes rough skin effect of cosmetics obtained in the various embodiments described above is evaluated in comparative analysis.Wherein, nourishes rough skin effect Fruit is dry skin, the colour of skin is dark yellow, Signs of fatigue is showed on one's face, the improvement situation of fat secretion, glossiness etc., the results are shown in Table 1.

Each embodiment and comparative example of table 1 improves the statistical form of situation to skin

From the data in the table, on prescription, using nourishing facial treatment milk obtained by Examples 1 to 3, shining skin effect is nourished Fruit is best, and removes the comparative example 1 of black bearberry leaf extract in prescription, the comparative example 2 of removal glycyrrhetinic acid, removes cell factor The shining skin effect of its nourishing of comparative example 3 is much not as good as Examples 1 to 3;Not as good as the prescription used, with embodiment 1, only preparation method is not yet It is same as the comparative example 4 of embodiment 1.It was therefore concluded that: black bearberry leaf extract, glycyrrhetinic acid and cell are raw in the present invention Synergistic effect is played in terms of nourishing shining skin between long factor three, indispensable, these ingredients and other some skin cares Moisturizing ingredient plays a role jointly.

The prescription of comparative example 4 is same as Example 1, and in preparation method, cell factor and house oil use in comparative example 4 Be the mode individually added, cell factor and house oil are first prepared into cell factor-house oil lotion in embodiment 1, then are added Add;Since the freezing point of house oil is 36-43 DEG C, cell factor can be made to be wrapped up by house oil in this way, thus with The isolation of other skin care ingredients, the effective protection activity of cell factor are allowed to persistently effectively, therefore using made from embodiment 1 Nourishing facial treatment milk, it nourishes shining skin effect, is much better than and nourishes facial treatment milk using made from comparative example 4;Simultaneously according to the present invention The shining skin lotion of nourishing of the method preparation of Examples 1 to 3 also extends the shelf-life of facial treatment milk.

Embodiment described above is merely a preferred embodiment of the present invention, and the simultaneously exhaustion of the feasible implementation of non-present invention.It is right For persons skilled in the art, any aobvious to made by it under the premise of without departing substantially from the principle of the invention and spirit and The change being clear to should be all contemplated as falling within claims of the invention.

Claims (4)

1. a kind of nourishing facial treatment milk, which is characterized in that it includes containing following components by percentage to the quality:
The nourishing facial treatment milk specifically comprises the following steps: when preparing
Step 1: weighing each component by above-mentioned mass percent proportion;
Step 2: house oil is heated to 40-50 DEG C of thawing, Porcine HGF is then added, after being uniformly dispersed, is rapidly cooled to House oil solidification, obtains cell factor-house oil lotion;
Step 3: by sad Propylheptyl, glucose aminoglucan, alcohols, carbomer, diethyl hexylcarbonate, surface-active Agent and water are added in emulsion tank, stir evenly, emulsify 30min after being heated to 80-90 DEG C;It is cooled to 40-50 DEG C, anti-corrosion is added Agent, black bearberry leaf extract, glycyrrhetinic acid, allantoin, pH adjusting agent, continue emulsify 10min after, be cooled to≤20 DEG C, then plus Enter the resulting cell factor of step 2-house oil paste, in≤20 DEG C stirring to be uniformly dispersed to get.
2. a kind of nourishing facial treatment milk according to claim 1, which is characterized in that the Porcine HGF is selected from cutin Porcine HGF, acid fibroblast growth factor, basic fibroblast growth factor, platelet derived growth factor and table One or more of skin growth factor;
The alcohols is selected from glycerol, propylene glycol, polyethylene glycol, polypropylene glycol, polytetramethylene glycol -8;Polytetramethylene glycol -5;Polytetramethylene glycol- One or more of 3;
The surfactant be selected from one of two laruyl alcohol citrates, -4 laurate of polyglycereol, glycerin polyether -26 or It is several;
The pH adjusting agent is selected from one or both of triethanolamine, arginine.
3. a kind of nourishing facial treatment milk according to claim 2, which is characterized in that it includes containing by percentage to the quality Following components:
4. a kind of nourishing facial treatment milk according to claim 1, which is characterized in that the water is deionized water.
CN201510713075.9A 2015-10-29 2015-10-29 A kind of nourishing facial treatment milk and preparation method thereof CN105193671B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008412A (en) * 2010-11-26 2011-04-13 新时代健康产业(集团)有限公司 Skin care composition with whitening efficacy, preparation and preparation method thereof
CN104856892A (en) * 2014-11-14 2015-08-26 广州远想生物科技有限公司 Cosmetic or skin care product preparation rich in growth factors and preparation method therefor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008412A (en) * 2010-11-26 2011-04-13 新时代健康产业(集团)有限公司 Skin care composition with whitening efficacy, preparation and preparation method thereof
CN104856892A (en) * 2014-11-14 2015-08-26 广州远想生物科技有限公司 Cosmetic or skin care product preparation rich in growth factors and preparation method therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"马油";向日葵之心射手;《https://baike.baidu.com/history/%E9%A9%AC%E6%B2%B9/86938855》;20151004;第1-2页

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