CN109363990A - A kind of old skin care compositions of removing wrinkle and resisting aging and its preparation method and application - Google Patents
A kind of old skin care compositions of removing wrinkle and resisting aging and its preparation method and application Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention discloses old skin care compositions of a kind of removing wrinkle and resisting aging and its preparation method and application.The old skin care compositions of the removing wrinkle and resisting aging, by weight percentage, comprising: monkey-bread tree berry extract 10~30%, adenosine 10~30%, camomile extract 10~30%, hyaluronic acid solution 1~10%, polypeptide complex 10~30%, deionized water surplus.The old skin care compositions of removing wrinkle and resisting aging provided by the invention has the characteristics that mild, non-stimulated, without side-effects using obvious effect, performance；Have the function of synergy, and simple production process, safety and environmental protection between each raw material, to environmental ecology close friend, there is high economic value；The old skin care compositions of removing wrinkle and resisting aging provided by the invention can also be added in other daily cosmetics, have extremely wide application value；Especially by the combined application in Essence, it is suitable for all kinds of skin quality, there is significant advantage in terms of the elasticity, anti-wrinkle, increase for improving skin.
Description
Technical field
The present invention relates to cosmetic technical field, in particular to a kind of old skin care compositions of removing wrinkle and resisting aging and preparation method thereof
And application.
Background technique
As international famous skin care science and technology constantly updates iteration, biotechnology, doctor's U.S. technology are continued to develop, and people are to skin care
The quality requirements of product are continuously improved, safely, effectively, innovation, mild, economic cry it is higher and higher；From the point of view of State-level, drum
Encourage innovation, enterprise should make unceasing progress breakthrough in respective industry, the advanced achievements found in practice be carried out further
Research is formed own technological contribution and barrier, how to be designed using the front line science in field, unique application and natural
Strength combines, and accomplishes 2 effect of 1+1 >, and is incorporated into the whole cosmetology idea of health, studies compound highly effective Almightiness type
Mixture is domestic brand power-assisted, is Cosmetics in China industry development trend.Based on this, traditional natural green plant how is screened
Essence is extracted, in conjunction with modern biotechnology fermentation technique product, combination among the strong ones, developing novel multi-effect can cooperate with the compound of promotion to be
The direction of technology development.Human skin because gravity factor, free radical infringement, own metabolism vigor decline and synthesis collagen or
The slow factor of person's hyaluronic acid, improperly skin care factor causes the generation of wrinkle；So from these angles, selection is suitable
Raw material, linkage effect is complementary mutually to promote to reach to delay wrinkle, or even mitigates depth wrinkly.
At present on the market, not yet someone is by monkey-bread tree berry extract, adenosine, camomile extract, hyaluronic acid, polypeptide
Combine and develops the skin care item with eliminating wrinkle, senile-resistant efficacy.
Summary of the invention
The purpose of the present invention is intended to provide a kind of old skin care compositions of removing wrinkle and resisting aging and its preparation method and application, to solve
Above-mentioned technical problem.
To achieve the goals above, the technical solution of the present invention is as follows:
In a first aspect, the old skin care compositions of a kind of removing wrinkle and resisting aging provided by the invention, by weight percentage, comprising: monkey
Breadfruit extract 10~30%, adenosine 10~30%, camomile extract 10~30%, hyaluronic acid solution 1~10%,
Polypeptide complex 10~30%, deionized water surplus.
Preferably, the old skin care compositions of the removing wrinkle and resisting aging, by weight percentage, comprising: monkey-bread tree berry extract
20~30%, adenosine 15~25%, camomile extract 15~25%, 1% hyaluronic acid solution 6~8%, polypeptide complex 15
~25%, deionized water surplus.
Preferably, the polypeptide complex is selected from palmityl tetrapeptide -7, Matrixyl -4, Argireline and carnosine
In at least two.
Preferably, the polypeptide complex is pressed by palmityl tetrapeptide -7, Matrixyl -4, Argireline and carnosine
It is formed according to 0.5~3:0.5~2:1~3:0.5~1 weight ratio.
Preferably, the Sodium Hyaluronate is 10~500,000 Dalton molecular weights.
Preferably, the sodium hyaluronate solution is to be made using following methods: by Hyal powder and deionization
After water mixing, it is stirred and heated to 80~90 DEG C under the revolving speed of 800~1200rpm/min, keeps the temperature 0.5~2 hour, until shape
At clear gum solution.
Second aspect, a kind of old skin care compositions of removing wrinkle and resisting aging as described in relation to the first aspect provided by the invention, including such as
Lower step:
(1) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；
(2) deionized water is added in step (1) resulting mixed liquor A, stirs 5~60 minutes, obtains mixed liquid B；
(3) sodium hyaluronate solution is added in step (2) resulting mixed liquid B, stirs 5~60 minutes, is mixed
Close liquid C；
(4) polypeptide complex is added in the resulting mixed liquor C of step (3), the insulated and stirred 5~60 at 30~50 DEG C
Minute, obtain the old skin care compositions of removing wrinkle and resisting aging.
The third aspect, the old skin care compositions of removing wrinkle and resisting aging of one kind provided by the invention as described in relation to the first aspect is in cosmetics
In application.
Fourth aspect, a kind of old Essence of removing wrinkle and resisting aging provided by the invention, by weight percentage, comprising: glycerol 1~
10%, propylene glycol 1~10%, the old skin care compositions of xanthan gum 0.05~1%, removing wrinkle and resisting aging as described in relation to the first aspect 5~
35%, deionized water surplus.
Preferably, weight percent of the old skin care compositions of the removing wrinkle and resisting aging in the old Essence of the removing wrinkle and resisting aging is
10~30%.
Compared with prior art, the beneficial effects of the present invention are:
(1) the old skin care compositions of removing wrinkle and resisting aging provided by the invention has using obvious effect, performance is mild, it is non-stimulated,
Feature without side-effects；
(2) raw material used in the old skin care compositions of removing wrinkle and resisting aging provided by the invention include adenosine, camomile extract,
Monkey-bread tree berry extract etc. has the function of synergy between each raw material, is combined into skin care raw material of new generation, accomplishes 1+1
2 effect of >, and be incorporated into the whole cosmetology idea of health, efficient Almightiness type mixture is domestic brand power-assisted, meets state
Interior cosmetics industry development trend also has good publicity effect and social value；
(3) simple production process of the old skin care compositions of removing wrinkle and resisting aging provided by the invention, safety and environmental protection, to environmental ecology
Close friend has high economic value；
(4) the old skin care compositions of removing wrinkle and resisting aging provided by the invention can also be added in other daily cosmetics, have
Extremely wide application value；Especially by the combined application in Essence, it is suitable for all kinds of skin quality, in the bullet for improving skin
Property, anti-wrinkle, increase skin firmness etc. there is significant advantage.
Specific embodiment
Specific embodiments of the present invention will be further explained below.It should be noted that for these implementations
The explanation of mode is used to help understand the present invention, but and does not constitute a limitation of the invention.In addition, invention described below
Technical characteristic involved in each embodiment can be combined with each other as long as they do not conflict with each other.
In a first aspect, the old skin care compositions of a kind of removing wrinkle and resisting aging provided by the invention, by weight percentage, comprising: monkey
Breadfruit extract 10~30%, adenosine 10~30%, camomile extract 10~30%, hyaluronic acid solution 1~10%,
Polypeptide complex 10~30%, deionized water surplus.
In embodiments of the present invention, the old skin care compositions of the removing wrinkle and resisting aging, by weight percentage, comprising: monkey face
Packet tree berry extract 20~30%, adenosine 15~25%, camomile extract 15~25%, 1% hyaluronic acid solution 6~8%,
Polypeptide complex 15~25%, deionized water surplus.
In embodiments of the present invention, the polypeptide complex is selected from palmityl tetrapeptide -7, Matrixyl -4, acetyl group
At least two in hexapeptide -8 and carnosine.
In embodiments of the present invention, the polypeptide complex is by palmityl tetrapeptide -7, Matrixyl -4, acetyl group six
Peptide -8 and carnosine are formed according to 0.5~3:0.5~2:1~3:0.5~1 weight ratio.
Further, the polypeptide complex is by palmityl tetrapeptide -7, Matrixyl -4, Argireline and carnosine
It is formed according to the weight ratio of 1:1:1:1.
In embodiments of the present invention, the Sodium Hyaluronate is 10~500,000 Dalton molecular weights.
In embodiments of the present invention, the sodium hyaluronate solution is to be made using following methods: by Sodium Hyaluronate
After powder is mixed with deionized water, it is stirred and heated to 80~90 DEG C under the revolving speed of 800~1200rpm/min, heat preservation 0.5~
2 hours, until forming clear gum solution.
In embodiments of the present invention, in the sodium hyaluronate solution Sodium Hyaluronate mass concentration be 0.01~
5%.
In embodiments of the present invention, the old skin care compositions of the removing wrinkle and resisting aging further includes preservative, and the preservative exists
Weight percent in the old skin care compositions of removing wrinkle and resisting aging is 0.01~0.5%.
Second aspect, a kind of old skin care compositions of removing wrinkle and resisting aging as described in relation to the first aspect provided by the invention, including such as
Lower step:
(1) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；
(2) deionized water is added in step (1) resulting mixed liquor A, stirs 5~60 minutes, obtains mixed liquid B；
(3) sodium hyaluronate solution is added in step (2) resulting mixed liquid B, stirs 5~60 minutes, is mixed
Close liquid C；
(4) polypeptide complex is added in the resulting mixed liquor C of step (3), the insulated and stirred 5~60 at 30~50 DEG C
Minute, obtain the old skin care compositions of removing wrinkle and resisting aging.
In the present invention, provided by the present invention that each functional component in wrinkle anti-apolexis composition is gone to be played the role of such as
Under:
(1) monkey-bread tree berry extract: monkey-bread tree scientific name is called Bo Babu tree, and the dimension that fruit contains high level is raw
Element, mineral matter element；Contain in monkey-bread tree berry extract there are many nutritional ingredient needed for skin, the AHA and polysaccharide that fruit contains
Mucus has moisturizing, and timely smooth wrinkle improves roughness, has the short-term compact sense for promoting effect, and long-time service has increase
Skin elasticity effect；
(2) adenosine: being a kind of endogenous nucleoside throughout human body cell, is in cell tissue metabolic processes in cell
A kind of aminoacid ingredient of interior generation；Adenosine is for synthesizing atriphos (ATP), adenine, adenylate, arabinosy ladenosine
Important intermediate；After adenosine enters skin, the energy feedstuff of horn cell can be provided, promotes cell viability, promotes cell
Metaboilic level；
(3) camomile extract: choosing the extract of German chamomile kind extraction, and chamomile can alleviate inflammation and pain
Symptom, also the effect of helpful sleep, alleviation is had a sleepless night as caused by neurotic skin scabies itching and pain；With excellent antiallergic function
Effect, effect depend primarily on following two chemical component:
1. azulene hydrocarbon (Azulene Azulene): the alias of azulene hydrocarbon is blue sesame oil hydrocarbon, german chamomile azulene, for the oil of blue
Insoluble liquid；It refines from german chamomile, chamomile and common milfoil essential oil；Azulene hydrocarbon has the function of antihistaminicum；Although it and one
As the drug of antihistaminicum compare, the time to play a role is slower, but degree of safety height is suitble to be used for a long time, so as subsensitivety
Daily maintenance ingredient is extremely safe, suitable long-time service；
2. bisabolol (Bisabolol): bisabolol is called bisabolol, be present in one of chamomile at
Point, itself is safe and reliable, and can antiallergic anti-inflammatory, nursing product or even toothpaste and gargle after being common in sun-proof, baby products and shaving
In water.
(4) Sodium Hyaluronate: being commonly called as sodium hyaluronate (SODIUMHYALURONATE), is by unit D-Glucose aldehydic acid and N-
The higher polysaccharides of acetylglucosamine composition.Belong to skin conditioner, be a kind of acid mucopolysaccharide, be naturally present in cornea skin,
The substance extracted in cockscomb can also be fermented by Lactococcus and is made, and for white or off-white color particle or powder, can absorb it
1000 times of moisture of body weight are lost by retaining moisture of skin, prevention moisture through epidermis with reaching, and when skin is damaged
When barrier reparation, enable skin not feel drying after, increase gloss, it can improve skin-nourishing metabolism, make skin
Soft, smooth, anti-wrinkle increases elasticity, prevents aging, is good skin penetration enhancer again while moisturizing.With other battalion
It supports components matching to use, the more preferable effect for promoting nutrient absorption can be played.
(5) polypeptide complex: the application select be palmityl tetrapeptide -7, Matrixyl -4, Argireline and
The combination collocation of carnosine；Wherein, palmityl tetrapeptide -7 is derived from a segment in Immunoglobulin IgG, this segment is by palm
It is easier after acyl modification by percutaneous absorption, and can significantly reduce the level of inflammatory factor interleukin (IL-6), have and eliminate skin
The effect of skin potential inflammation, antiallergic is generated to wrinkle is mitigated, and restoring skin vigor has remarkable efficacy；Matrixyl -4 is I
Collagen type precursor series segment, it can fibroblastic growth in intense stimulus extracellular matrix (ECM), to stimulate
The synthesis of I and type III collagen and fibrin and hyaluronic acid, to deep wrinkles significant effect；Argireline is
The mild Botox substitute of safety, can mitigate wrinkle caused by being shunk by mimetic muscle in a short time, especially in eye circumference, preceding
The wrinkle of volume and the corners of the mouth, such as crow's feet, decree line, corners of the mouth line；Carnosine is a kind of potent antioxidant and anti-protein sugar agent,
It efficiently captures the intracorporal oxygen radical of people and resists skin protein glycosylation cross-linking reaction, slow down skin aging；Said components
Synergistic effect not only can it is long-acting but also can be short-acting resistance wrinkle, simultaneously because the synergistic effect of other raw materials, it is ensured that core
The effect of ingredient, maximizes.
The third aspect, the old skin care compositions of removing wrinkle and resisting aging of one kind provided by the invention as described in relation to the first aspect is in cosmetics
In application.
Fourth aspect, a kind of old Essence of removing wrinkle and resisting aging provided by the invention, by weight percentage, comprising: glycerol 1~
10%, propylene glycol 1~10%, the old skin care compositions of xanthan gum 0.05~1%, removing wrinkle and resisting aging as described in relation to the first aspect 5~
35%, deionized water surplus.
In embodiments of the present invention, the old skin care compositions of the removing wrinkle and resisting aging is in the old Essence of the removing wrinkle and resisting aging
Weight percent is 10~30%.
Embodiment is described in detail below.Camomile extract, monkey-bread tree berry extract are equal in following embodiment
To take water as a solvent and using liquid extract made from routine techniques.
Embodiment 1
A kind of preparation method of the old skin care compositions of removing wrinkle and resisting aging provided in this embodiment, includes the following steps:
(1) after mixing Hyal powder according to the weight ratio of 1:99 with deionized water, in turning for 1000rpm/min
It is stirred and heated to 85 DEG C under speed, keeps the temperature 1 hour, until forming clear gum solution；
(2) following raw materials by weight percentage: monkey-bread tree berry extract 24%, adenosine 18%, chamomile are weighed
Extract 22%, hyaluronic acid solution 7.5%, palmityl tetrapeptide -7 5%, Matrixyl -4 5%, Argireline
5%, carnosine 5%, preservative 0.1%, deionized water surplus；
(3) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；Deionized water is added in resulting mixed liquor A, stirs 20 minutes, obtains mixed liquid B；Sodium Hyaluronate is molten
Liquid is added in resulting mixed liquid B, is stirred 20 minutes, is obtained mixed liquor C；By palmityl tetrapeptide -7, Matrixyl -4, second
Acyl group hexapeptide -8, carnosine are added in resulting mixed liquor C, and insulated and stirred 30 minutes at 40 DEG C obtain removing wrinkle and resisting aging and protect always
Skin composition.
Embodiment 2
A kind of preparation method of the old skin care compositions of removing wrinkle and resisting aging provided in this embodiment, includes the following steps:
(1) after mixing Hyal powder according to the weight ratio of 2:98 with deionized water, in turning for 1000rpm/min
It is stirred and heated to 85 DEG C under speed, keeps the temperature 1 hour, until forming clear gum solution；
(2) following raw materials by weight percentage: monkey-bread tree berry extract 30%, adenosine 15%, chamomile are weighed
Extract 15%, hyaluronic acid solution 8%, palmityl tetrapeptide -7 5%, Matrixyl -4 10%, Argireline
5%, carnosine 5%, preservative 0.2%, deionized water surplus；
(3) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；Deionized water is added in resulting mixed liquor A, stirs 20 minutes, obtains mixed liquid B；Sodium Hyaluronate is molten
Liquid is added in resulting mixed liquid B, is stirred 20 minutes, is obtained mixed liquor C；By palmityl tetrapeptide -7, Matrixyl -4, second
Acyl group hexapeptide -8, carnosine are added in resulting mixed liquor C, and insulated and stirred 20 minutes at 30 DEG C obtain removing wrinkle and resisting aging and protect always
Skin composition.
Embodiment 3
A kind of preparation method of the old skin care compositions of removing wrinkle and resisting aging provided in this embodiment, includes the following steps:
(1) after mixing Hyal powder according to the weight ratio of 2:98 with deionized water, in turning for 1000rpm/min
It is stirred and heated to 85 DEG C under speed, keeps the temperature 1 hour, until forming clear gum solution；
(2) following raw materials by weight percentage: monkey-bread tree berry extract 20%, adenosine 25%, chamomile are weighed
Extract 25%, hyaluronic acid solution 6%, palmityl tetrapeptide -7 5%, Matrixyl -4 2.5%, Argireline
5%, carnosine 2.5%, preservative 0.1%, deionized water surplus；
(3) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；Deionized water is added in resulting mixed liquor A, stirs 10 minutes, obtains mixed liquid B；Sodium Hyaluronate is molten
Liquid is added in resulting mixed liquid B, is stirred 20 minutes, is obtained mixed liquor C；By palmityl tetrapeptide -7, Matrixyl -4, second
Acyl group hexapeptide -8, carnosine are added in resulting mixed liquor C, and insulated and stirred 30 minutes at 40 DEG C obtain removing wrinkle and resisting aging and protect always
Skin composition.
Embodiment 4
A kind of preparation method of the old skin care compositions of removing wrinkle and resisting aging provided in this embodiment, includes the following steps:
(1) after mixing Hyal powder according to the weight ratio of 1:99 with deionized water, in turning for 1000rpm/min
It is stirred and heated to 85 DEG C under speed, keeps the temperature 1 hour, until forming clear gum solution；
(2) following raw materials by weight percentage: monkey-bread tree berry extract 24%, adenosine 20%, chamomile are weighed
Extract 20%, hyaluronic acid solution 7%, palmityl tetrapeptide -7 7.5%, Matrixyl -4 2.5%, Argireline
7.5%, carnosine 2.5%, preservative 0.15%, deionized water surplus；
(3) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；Deionized water is added in resulting mixed liquor A, stirs 10 minutes, obtains mixed liquid B；Sodium Hyaluronate is molten
Liquid is added in resulting mixed liquid B, is stirred 30 minutes, is obtained mixed liquor C；By palmityl tetrapeptide -7, Matrixyl -4, second
Acyl group hexapeptide -8, carnosine are added in resulting mixed liquor C, and insulated and stirred 5~60 minutes, it is old to obtain removing wrinkle and resisting aging at 45 DEG C
Skin care compositions.
Embodiment 5
A kind of preparation method of the old skin care compositions of removing wrinkle and resisting aging provided in this embodiment, includes the following steps:
(1) after mixing Hyal powder according to the weight ratio of 5:100 with deionized water, 1000rpm/min's
It is stirred and heated to 85 DEG C under revolving speed, keeps the temperature 1 hour, until forming clear gum solution；
(2) following raw materials by weight percentage: monkey-bread tree berry extract 27%, adenosine 21%, chamomile are weighed
Extract 19%, hyaluronic acid solution 6%, palmityl tetrapeptide -7 7%, Matrixyl -4 3.5%, Argireline
7%, carnosine 3.5%, preservative 0.1%, deionized water surplus；
(3) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are obtained
Mixed liquor A；Deionized water is added in resulting mixed liquor A, stirs 10 minutes, obtains mixed liquid B；Sodium Hyaluronate is molten
Liquid is added in resulting mixed liquid B, is stirred 30 minutes, is obtained mixed liquor C；By palmityl tetrapeptide -7, Matrixyl -4, second
Acyl group hexapeptide -8, carnosine are added in resulting mixed liquor C, and insulated and stirred 30 minutes at 40 DEG C obtain removing wrinkle and resisting aging and protect always
Skin composition.
Embodiment 6
The old skin care compositions of removing wrinkle and resisting aging, the present embodiment is made using preparation method similar to Example 1 in the present embodiment
It is only that raw material is different from the difference of embodiment 1, the raw material that the present embodiment uses, by weight percentage, comprising: monkey-bread tree
Berry extract 30%, adenosine 18%, camomile extract 22%, hyaluronic acid solution 7.5%, palmityl tetrapeptide -7 2.5%,
Matrixyl -4 2.5%, Argireline 2.5%, carnosine 2.5%, preservative 0.1%, deionized water surplus.
Comparative example 1
The old skin care compositions of removing wrinkle and resisting aging, this comparative example is made using preparation method similar to Example 1 in this comparative example
It is only that raw material is different from the difference of embodiment 1, the raw material that this comparative example uses, by weight percentage, comprising: adenosine
18%, camomile extract 22%, hyaluronic acid solution 7.5%, palmityl tetrapeptide -7, Matrixyl -4, acetyl group hexapeptide -
8, carnosine 20%, preservative 0.1%, deionized water surplus.
Comparative example 2
The old skin care compositions of removing wrinkle and resisting aging, this comparative example is made using preparation method similar to Example 1 in this comparative example
It is only that raw material is different from the difference of embodiment 1, the raw material that this comparative example uses, by weight percentage, comprising: monkey-bread tree
Berry extract 24%, camomile extract 22%, hyaluronic acid solution 7.5%, palmityl tetrapeptide -7, Matrixyl -4, second
Acyl group hexapeptide -8, carnosine 20%, preservative 0.1%, deionized water surplus.
Comparative example 3
The old skin care compositions of removing wrinkle and resisting aging, this comparative example is made using preparation method similar to Example 1 in this comparative example
It is only that raw material is different from the difference of embodiment 1, the raw material that this comparative example uses, by weight percentage, comprising: monkey-bread tree
Berry extract 24%, adenosine 18%, hyaluronic acid solution 7.5%, palmityl tetrapeptide -7, Matrixyl -4, acetyl group hexapeptide -
8, carnosine 20%, preservative 0.1%, deionized water surplus.
Comparative example 4
The old skin care compositions of removing wrinkle and resisting aging, this comparative example is made using preparation method similar to Example 1 in this comparative example
It is only that raw material is different from the difference of embodiment 1, the raw material that this comparative example uses, by weight percentage, comprising: monkey-bread tree
Berry extract 24%, adenosine 18%, camomile extract 22%, palmityl tetrapeptide -7, Matrixyl -4, acetyl group hexapeptide -
8, carnosine 20%, preservative 0.1%, deionized water surplus.
Comparative example 5
The old skin care compositions of removing wrinkle and resisting aging, this comparative example is made using preparation method similar to Example 1 in this comparative example
It is only that raw material is different from the difference of embodiment 1, the raw material that this comparative example uses, by weight percentage, comprising: monkey-bread tree
Berry extract 24%, adenosine 18%, camomile extract 22%, hyaluronic acid solution 7.5%, preservative 0.1%, deionized water
Surplus.
Application Example 1
The preparation method for the old Essence of removing wrinkle and resisting aging that this application embodiment provides, includes the following steps:
Weigh following raw material by weight percentage: glycerol 5%, propylene glycol 5%, xanthan gum 0.2%, 1 institute of embodiment
The old skin care compositions 10% of removing wrinkle and resisting aging, the preservative 0.5%, deionized water surplus obtained；Glycerol, propylene glycol, xanthan gum is pre-
First mixing is uniformly dispersed, and deionized water is being added, is being heated to 80 DEG C, insulated and stirred 15 minutes, after being cooled to 40 DEG C, adds and dispel
Wrinkle ageing-resistant skin care composition continues stirring 15 minutes, is eventually adding preservative, stirs evenly that removing wrinkle and resisting aging can be obtained is always smart
Magnificent liquid.
Application Example 2
The preparation method for the old Essence of removing wrinkle and resisting aging that this application embodiment provides, includes the following steps:
Weigh following raw material by weight percentage: glycerol 5%, propylene glycol 5%, xanthan gum 0.2%, 1 institute of embodiment
The old skin care compositions 15% of removing wrinkle and resisting aging, the preservative 0.5%, deionized water surplus obtained；Glycerol, propylene glycol, xanthan gum is pre-
First mixing is uniformly dispersed, and deionized water is being added, is being heated to 80 DEG C, insulated and stirred 15 minutes, after being cooled to 40 DEG C, adds and dispel
Wrinkle ageing-resistant skin care composition continues stirring 15 minutes, is eventually adding preservative, stirs evenly that removing wrinkle and resisting aging can be obtained is always smart
Magnificent liquid.
Application Example 3
The preparation method for the old Essence of removing wrinkle and resisting aging that this application embodiment provides, includes the following steps:
Weigh following raw material by weight percentage: glycerol 5%, propylene glycol 5%, xanthan gum 0.2%, 1 institute of embodiment
The old skin care compositions 20% of removing wrinkle and resisting aging, the preservative 0.5%, deionized water surplus obtained；Glycerol, propylene glycol, xanthan gum is pre-
First mixing is uniformly dispersed, and deionized water is being added, is being heated to 80 DEG C, insulated and stirred 15 minutes, after being cooled to 40 DEG C, adds and dispel
Wrinkle ageing-resistant skin care composition continues stirring 15 minutes, is eventually adding preservative, stirs evenly that removing wrinkle and resisting aging can be obtained is always smart
Magnificent liquid.
Application Example 4~13
" 1~5 old skin care compositions of resulting removing wrinkle and resisting aging of the embodiment of the present invention 2~6 and comparative example " replacement is respectively adopted
Above-mentioned " the old skin care compositions 5% of the resulting removing wrinkle and resisting aging of embodiment 1 " is then made according to the preparation method of Application Example 1
The old Essence of removing wrinkle and resisting aging.
Compare Application Example 1
The preparation method for the Essence that this comparison Application Example provides, includes the following steps:
Weigh following raw material by weight percentage: glycerol 5%, propylene glycol 5%, xanthan gum 0.2%, preservative
0.5%, deionized water surplus；Glycerol, propylene glycol, xanthan gum are pre-mixed and are uniformly dispersed, deionized water is being added, is being heated to
80 DEG C, insulated and stirred 15 minutes, after being cooled to 40 DEG C, preservative is added, stirs evenly and Essence can be obtained.
Beneficial effect in order to further illustrate the present invention carries out clinical examination to the old Essence of above-mentioned 14 kinds of removing wrinkle and resisting agings
It tests:
(1) according to the ratio of men and women 1:1, select the age in 30-50 years old volunteer, no skin medical history is divided into 25 people/group,
Totally 15 groups, wherein one group will do control group, not use any product, 14 groups use above-mentioned Application Example and comparative example respectively
The old Essence of the resulting 14 kinds of removing wrinkle and resisting agings of Application Example；It as far as possible include slight ripple, deep wrinkles in every group of 25 people
Personage.On-test, tests the initial lines of each tester and the skin degree of packing, the indices such as elasticity, and records just
Initial value.
(2) detecting instrument: rich to automatically analyze skin detection system model: CBS-1800 depending on electronics；
(3) it testing principle: uses and detects a kind of skin image processing system of the mirror technology Jing Guo digital processing, it can be seen that
The health status of pigment and skin under skin, and can change with time to measure and monitor these variations.
(4) the tested time: 6 weeks；
(5) test position: canthus, forehead, the corners of the mouth；
(6) test mode and requirement: it is each using once daily morning and evening, conscientiously smear.After 6 weeks, it is every to reuse instrument detection
One subject, wrinkle, elasticity and the skin degree of packing improve 30% or more and then record a people.
1 clinical trial results of table
Interpretation of result:
By the clinical trial result of 1~3 gained Essence of Application Example in table 1 it is found that in Essence anti-wrinkle resist
The recovery effects of the raising of the adding proportion of aging skin care compositions, skin are better, and proportional example is related；With Application Example 9
~13 resulting Essences are compared, and Application Example 1,4~8 resulting Essences can preferably maintain the good shape of skin
State is used for a long time, and has excellent performance in terms of anti-wrinkle, increase skin firmness, improvement skin elasticity, this also illustrates that anti-wrinkle is anti-
Each raw material is indispensable in aging skin care compositions, has the function of synergy between each other.
Above the embodiments of the present invention are described in detail, but the present invention is not limited to described embodiments.It is right
For those skilled in the art, in the case where not departing from the principle of the invention and spirit, these embodiments are carried out more
Kind change, modification, replacement and modification, still fall in protection scope of the present invention.
Claims (10)
1. a kind of old skin care compositions of removing wrinkle and resisting aging, which is characterized in that by weight percentage, comprising: monkey-bread tree fruit is extracted
Object 10~30%, adenosine 10~30%, camomile extract 10~30%, hyaluronic acid solution 1~10%, polypeptide complex 10
~30%, deionized water surplus.
2. the old skin care compositions of removing wrinkle and resisting aging according to claim 1, which is characterized in that the old skin care group of removing wrinkle and resisting aging
Object is closed, by weight percentage, comprising: monkey-bread tree berry extract 20~30%, adenosine 15~25%, camomile extract 15
~25%, 1% hyaluronic acid solution 6~8%, polypeptide complex 15~25%, deionized water surplus.
3. the old skin care compositions of removing wrinkle and resisting aging according to claim 1, which is characterized in that the polypeptide complex is selected from palm fibre
At least two in palmitic acid acyl tetrapeptide -7, Matrixyl -4, Argireline and carnosine.
4. the old skin care compositions of removing wrinkle and resisting aging according to claim 1, which is characterized in that the polypeptide complex is by palm
Acyl tetrapeptide -7, Matrixyl -4, Argireline and carnosine are according to 0.5~3:0.5~2:1~3:0.5~1 weight ratio
Composition.
5. the old skin care compositions of removing wrinkle and resisting aging according to claim 1, which is characterized in that the Sodium Hyaluronate be 10~
500000 Dalton molecular weights.
6. the old skin care compositions of removing wrinkle and resisting aging according to claim 1, which is characterized in that the sodium hyaluronate solution is
It is made using following methods: after Hyal powder is mixed with deionized water, under the revolving speed of 800~1200rpm/min
80~90 DEG C are stirred and heated to, keeps the temperature 0.5~2 hour, until forming clear gum solution.
7. a kind of such as the old skin care compositions of removing wrinkle and resisting aging according to any one of claims 1 to 6, which is characterized in that including such as
Lower step:
(1) adenosine, camomile extract, monkey-bread tree berry extract are mixed, until adenosine is completely dissolved, are mixed
Liquid A；
(2) deionized water is added in step (1) resulting mixed liquor A, stirs 5~60 minutes, obtains mixed liquid B；
(3) sodium hyaluronate solution is added in step (2) resulting mixed liquid B, stirs 5~60 minutes, obtains mixed liquor
C；
(4) polypeptide complex is added in the resulting mixed liquor C of step (3), 5~60 points of insulated and stirred at 30~50 DEG C
Clock obtains the old skin care compositions of removing wrinkle and resisting aging.
8. a kind of such as application of the old skin care compositions of removing wrinkle and resisting aging according to any one of claims 1 to 6 in cosmetics.
9. a kind of old Essence of removing wrinkle and resisting aging, which is characterized in that by weight percentage, comprising: glycerol 1~10%, propylene glycol 1
~10%, the old skin care compositions of xanthan gum 0.05~1%, removing wrinkle and resisting aging such as according to any one of claims 1 to 5 5~
35%, deionized water surplus.
10. the old Essence of removing wrinkle and resisting aging according to claim 9, which is characterized in that the old skincare composition of removing wrinkle and resisting aging
Weight percent of the object in the old Essence of the removing wrinkle and resisting aging is 10~30%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811428430.8A CN109363990A (en) | 2018-11-27 | 2018-11-27 | A kind of old skin care compositions of removing wrinkle and resisting aging and its preparation method and application |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811428430.8A CN109363990A (en) | 2018-11-27 | 2018-11-27 | A kind of old skin care compositions of removing wrinkle and resisting aging and its preparation method and application |
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| Publication Number | Publication Date |
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| CN109363990A true CN109363990A (en) | 2019-02-22 |
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ID=65377381
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585085A (en) * | 2019-09-28 | 2019-12-20 | 广东丸美生物技术股份有限公司 | Nano-gold soft film powder composition and preparation method and application thereof |
| CN110934772A (en) * | 2019-12-25 | 2020-03-31 | 珠海贝美生物科技有限公司 | Wrinkle-removing and anti-aging composition and application thereof in cosmetics |
| CN112006931A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Anti-aging anti-wrinkle essence and preparation process thereof |
| CN113456553A (en) * | 2021-07-29 | 2021-10-01 | 加来(济南)生活科技有限公司 | Anti-aging brightening composition and anti-aging brightening essence containing Paeonia suffruticosa pulp extract and preparation method thereof |
-
2018
- 2018-11-27 CN CN201811428430.8A patent/CN109363990A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585085A (en) * | 2019-09-28 | 2019-12-20 | 广东丸美生物技术股份有限公司 | Nano-gold soft film powder composition and preparation method and application thereof |
| CN110934772A (en) * | 2019-12-25 | 2020-03-31 | 珠海贝美生物科技有限公司 | Wrinkle-removing and anti-aging composition and application thereof in cosmetics |
| CN112006931A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Anti-aging anti-wrinkle essence and preparation process thereof |
| CN113456553A (en) * | 2021-07-29 | 2021-10-01 | 加来(济南)生活科技有限公司 | Anti-aging brightening composition and anti-aging brightening essence containing Paeonia suffruticosa pulp extract and preparation method thereof |
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