CN111700849A - Whitening composition, cosmetic and application - Google Patents
Whitening composition, cosmetic and application Download PDFInfo
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- CN111700849A CN111700849A CN202010759763.XA CN202010759763A CN111700849A CN 111700849 A CN111700849 A CN 111700849A CN 202010759763 A CN202010759763 A CN 202010759763A CN 111700849 A CN111700849 A CN 111700849A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention provides a whitening composition which comprises the following raw materials in parts by weight: 0.5-8 parts of lactobacillus/rice fermentation product, 1-9 parts of green lemon fermentation raw pulp, 0.01-1.5 parts of truffle extract and 0.01-1 part of pomelo oil tea extract. The whitening composition is prepared by mixing the lactobacillus/rice fermentation product, the green lemon fermentation raw stock, the white truffle extract and the pomelo oil tea extract; the components of the whitening anti-aging active substance provided by the invention have the functions of mutual matching and synergistic interaction, and can obtain outstanding whitening and antioxidant effects.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a whitening composition, a cosmetic and an application.
Background
Asian women are beautiful from ancient times, with the improvement of modern living standard, more and more people pay attention to external images, show people to increase confidence with beautiful images, and simultaneously, under the beautiful images, people pursue skin health more, and show people's pursuit of high-end life with healthy skin and beautiful images. Therefore, whitening skin care products are always sought, and the market share is large.
The whitening cosmetics are physically covered and whitened, physically and chemically stripped and then interfere and block the normal metabolism of melanin. In asia range, natural and synthetic whitening agents are widely used in the cosmetic field, wherein the main mechanism of action and whitening components are: ascorbic acid, arbutin, glycyrrhizic acid, tocopherol ferulate, kojic acid, etc. for inhibiting tyrosinase activity; lactic acid and its salts for reducing tyrosinase synthesis; glucosamine and tunicamycin for reducing tyrosinase migration; a compound having a serine residue which inhibits the conversion of melanocytes to keratinocytes; fruit acid, salicylic acid, citric acid, etc. for accelerating skin renewal and whitening skin.
Although there are many whitening agents on the market, some whitening agents have problems in use, and for example, research shows that some synthetic skin whitening agents, such as hydroquinone or kojic acid, may irritate the skin and even cause severe skin inflammation. Whitening agents are generally easy to oxidize, and the stability of the formula is obviously affected when the addition amount is large, so that the stability and the high efficiency are often difficult to be considered at the same time. High-concentration acids can remove cutin to achieve good whitening effect, but can cause serious damage to the natural protective layer of the skin to cause skin damage, so that the color of the skin is uneven, and the skin is more sensitive after the acid is used for removing the cutin. The whitening component aiming at tyrosinase activity needs to penetrate through stratum corneum and can only play a role in epidermis, and the active substances are simply added into a formula and are difficult to penetrate, and even the accumulation range on the surface of the skin generates negative effects on the skin. Whitening products have been developed since the advent, but the above-mentioned whitening approaches have caused varying degrees of skin damage to consumers.
Therefore, modern whitening product research should tend to natural plant extracts without toxic effects. Under the condition of not destroying the normal metabolism of skin melanin, the method accelerates the metabolic process of melanocytes, shortens the physiological cycle of the melanocytes, prevents the melanin from being excessively deposited to form color spots, increases the blood circulation of the skin and ensures that the skin really achieves the healthy and fair skin from inside to outside.
In summary, there is a need to provide a whitening cosmetic that is safe, non-irritating, highly stable, and easily permeable to whitening components, and has excellent whitening effects, to meet the needs of people.
Disclosure of Invention
In view of the above, the technical problem to be solved by the present invention is to provide a whitening composition, which has good whitening effect and good stability.
The invention provides a whitening composition which comprises the following raw materials in parts by weight:
0.5-8 parts of lactobacillus/rice fermentation product, 1-9 parts of green lemon fermentation raw pulp, 0.01-1.5 parts of truffle extract and 0.01-1 part of pomelo oil tea extract.
Preferably, the whitening composition comprises the following raw materials in parts by weight:
1-7 parts of lactobacillus/rice fermentation product, 2-8 parts of green lemon fermentation raw stock, 0.1-1.3 parts of truffle extract and 0.1-0.9 part of pomelo oil tea extract.
Preferably, the whitening composition comprises the following raw materials in parts by weight:
2-6 parts of lactobacillus/rice fermentation product, 3-7 parts of green lemon fermentation raw stock, 0.2-1.2 parts of truffle extract and 0.2-0.8 part of pomelo oil tea extract.
The invention provides application of the whitening composition in any one of the technical schemes in preparation of cosmetics.
The invention provides a whitening cosmetic, which comprises the composition in any one of the technical schemes and an auxiliary material acceptable in the field of cosmetics.
Preferably, the preservative comprises a preservative, a solvent and the following components:
0.5-25 parts by weight of the composition according to any one of the above technical schemes;
preferably, the humectant is selected from one or more of glycerol, propylene glycol, 1, 3-propylene glycol, butanediol, hydroxyethyl urea, ceramide, sodium hyaluronate, levan, allantoin, luba oil, trehalose, sorbitol or betaine;
the emulsifier is selected from cetostearyl alcohol, cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, glyceryl stearate alcohol, polysorbates, alkyl glucosides or sodium stearyl glutamate
The emollient is selected from one or more of wheat germ oil, macadamia nut oil, jojoba oil, avocado oil, shea butter, sweet almond oil, Coicis semen oil, rice bran oil, safflower oil or myristyl myristate.
The thickener is selected from one or more of xanthan gum, carbomer, cellulose and modified substances thereof, polyacrylamide or sodium acrylate/sodium acryloyldimethyl taurate copolymer;
the pH regulator is one or two of citric acid and triethanolamine.
Preferably, the pH value of the cosmetic is 5-7.
Preferably, the cosmetic product is in the form of a mask, water, lotion or cream.
The invention provides a preparation method of a whitening cosmetic in any one of the technical schemes, which comprises the following steps:
heating and mixing a solvent, a thickening agent and a humectant, and stirring to obtain a first mixture;
mixing the emollient and the emulsifier, and heating and stirring to obtain a second mixture;
homogenizing and emulsifying the first mixture and the second mixture, stirring, mixing with the composition and the preservative in any one of the technical schemes, stirring, and cooling to obtain the composition.
Compared with the prior art, the invention provides a whitening composition which comprises the following raw materials in parts by weight: 0.5-8 parts of lactobacillus/rice fermentation product, 1-9 parts of green lemon fermentation raw pulp, 0.01-1.5 parts of truffle extract and 0.01-1 part of pomelo oil tea extract. The whitening composition is prepared by mixing the lactobacillus/rice fermentation product, the green lemon fermentation raw stock, the white truffle extract and the pomelo oil tea extract; the components of the whitening anti-aging active substance provided by the invention have the functions of mutual matching and synergistic interaction, and can obtain outstanding whitening and antioxidant effects.
Detailed Description
The invention provides a whitening composition, a cosmetic and application, and a person skilled in the art can appropriately improve process parameters for realization by referring to the content. It is expressly intended that all such similar substitutes and modifications apparent to those skilled in the art are deemed to be within the scope of the invention. While the methods and applications of this invention have been described in terms of preferred embodiments, it will be apparent to those of ordinary skill in the art that variations and modifications in the methods and applications described herein, as well as other suitable variations and combinations, may be made to implement and use the techniques of this invention without departing from the spirit and scope of the invention.
The invention provides a whitening composition which comprises the following raw materials in parts by weight:
0.5-8 parts of lactobacillus/rice fermentation product, 1-9 parts of green lemon fermentation raw pulp, 0.01-1.5 parts of truffle extract and 0.01-1 part of pomelo oil tea extract.
The whitening composition provided by the invention comprises 0.5-8 parts by weight of lactobacillus/rice fermentation product; preferably 1-7 parts by weight of lactobacillus/rice fermentation product; more preferably, the lactobacillus/rice fermentation product comprises 2-6 parts of lactobacillus/rice fermentation product.
The rice contains starch, protein, fat, carbohydrate, vitamin B group, various organic acids, fructose, iron, phosphorus, magnesium, potassium, calcium, etc. The active components of the polysaccharide obtained from the rice fermented by the lactic acid bacteria have smaller molecular weight, are easier to be absorbed by skin, and have the effects of whitening, moisturizing and the like with higher efficiency. Can protect skin against ultraviolet radiation, and prevent melanin generation to achieve skin whitening effect.
The raw materials or auxiliary materials used in the invention can be purchased from the market. Preferably, the lactobacillus/rice fermentation product and the lime fermented puree of the present invention are obtained from shanghai xianjiao biotechnology limited.
The whitening composition provided by the invention comprises 1-9 parts by weight of fermented lime juice; preferably, the green lemon fermented raw pulp comprises 2-8 parts by weight of green lemon fermented raw pulp; more preferably, the fermented green lemon juice comprises 3-7 parts by weight of fermented green lemon juice; most preferably 4-6 parts of the fermented lime juice.
The green lemon is evergreen small arbor of Citrus of Rutaceae, and has warm sexual desire, yin resistance and heat intolerance. The fruits are green and oval, contain rich vitamin C, and are helpful for promoting metabolism, delaying aging, enhancing body resistance and the like. However, besides the body building effect, the lemon is also a food with quite high beauty value, not only has the whitening effect, but also has the unique fruit acid component which can soften the cuticle and enable the skin to become white and glossy. The green lemon contains up to four percent of organic acid, can be neutralized with alkaline matters on the surface of the skin, prevents and removes pigmentation in the skin, and removes grease dirt. The powerful efficacies of whitening and shrinking the burr are very popular.
The polysaccharide transmittance in the green lemon fermented raw stock is gradually increased along with the increase of the transdermal time. The result shows that the polysaccharide of the fermented lime pulp of the green lemon has small molecular weight and can permeate the skin, and the permeation rate is increased along with the prolonging of the transdermal time.
The raw materials or auxiliary materials used in the invention can be purchased from the market. Preferably, the lactobacillus/rice fermentation product and the lime fermented puree of the present invention are obtained from shanghai xianjiao biotechnology limited.
The whitening composition provided by the invention comprises 0.01-1.5 parts by weight of truffle extract; preferably comprises 0.1 to 1.3 weight parts of truffle extractive; more preferably, the extract of the truffle comprises 0.2 to 1.2 weight parts of truffle.
Truffle extract: an active ingredient extracted from white lump of Italian fungus (Latin name: T. magnatum vitad). The truffle belongs to one of truffles, has the price which is several times higher than that of common truffle, is more abundant in active components, is rich in more than 50 active components, comprises 17 amino acids (comprising 8 essential amino acids which can not be synthesized by human bodies), 8 vitamins, proteins, various unsaturated fatty acids, zinc, manganese, iron, phosphorus, selenium and other essential trace elements, and a large amount of metabolites such as male ketone, sphingolipid, truffle acid, sterol, truffle polysaccharide polypeptide, fatty acid, trace elements and the like, and can effectively decompose and metabolize melanin, thereby inhibiting the generation of the melanin and realizing the whitening effect.
The raw materials or auxiliary materials used in the invention can be purchased from the market. Preferably, the extract of trufflera albopictus is available from demi (shanghai) limited.
The whitening composition provided by the invention comprises 0.01-1 part by weight of a shaddock oil tea extract; preferably comprises 0.1 to 0.9 weight part of the shaddock oil tea extract; more preferably, the grapefruit oil tea extract is 0.2-0.8 weight part.
The pomelo oil tea extract of the invention contains rich tea saponin. The pomelo oil tea extract used in the present invention is commercially available. Preferably, the grapefruit oil tea extract is purchased from west anserin biotech limited.
In a part of preferred embodiments of the present invention, the whitening composition comprises the following raw materials in parts by weight:
1-7 parts of lactobacillus/rice fermentation product, 2-8 parts of green lemon fermentation raw stock, 0.1-1.3 parts of truffle extract and 0.1-0.9 part of pomelo oil tea extract.
In a part of preferred embodiments of the present invention, the whitening composition comprises the following raw materials in parts by weight:
2-6 parts of lactobacillus/rice fermentation product, 3-7 parts of green lemon fermentation raw stock, 0.2-1.2 parts of truffle extract and 0.2-0.8 part of pomelo oil tea extract.
The invention provides a preparation method of a whitening composition, which comprises the following raw materials in parts by weight:
mixing lactobacillus/rice fermented product, fermented pulp of fructus Citri Limoniae, herba Albiziae extract and fructus Citri Grandis oil tea extract.
The mixing method of the present invention is not limited, and the method may be commercially available.
The whitening composition is prepared by mixing the lactobacillus/rice fermentation product, the green lemon fermentation raw stock, the white truffle extract and the pomelo oil tea extract; the components of the whitening anti-aging active substance provided by the invention have the functions of mutual matching and synergistic interaction, and can obtain outstanding whitening and antioxidant effects.
The invention provides application of the whitening composition in any one of the technical schemes in preparation of cosmetics.
The invention provides a whitening cosmetic, which comprises the composition in any one of the technical schemes and an auxiliary material acceptable in the field of cosmetics.
The present invention is not limited to the auxiliary materials acceptable in the cosmetic field, and those skilled in the art are familiar with them.
The invention provides a whitening cosmetic, which comprises a preservative, a solvent and the following components:
0.5-25 parts by weight of the composition according to any one of the above technical schemes;
the invention provides a whitening cosmetic which comprises the following components in parts by weight, wherein if the total weight is 100%, the mass percent is equal to 100%.
The whitening cosmetic provided by the invention comprises a preservative.
The preservative provided by the invention comprises one or two of phenoxyethanol, potassium sorbate, sodium benzoate and chlorphenesin.
The whitening cosmetic provided by the invention comprises a solvent, wherein the solvent is water.
The whitening cosmetic provided by the invention comprises 0.5-25 parts by weight of the composition in any one of the technical schemes; preferably 1 to 23 parts by weight; more preferably 2 to 21 parts by weight; most preferably 3 to 18 parts by weight; most preferably 4 to 16 parts by weight.
The whitening cosmetic provided by the invention comprises 2-15 parts by weight of a humectant; preferably, the humectant comprises 3-15 parts by weight of humectant; more preferably, the humectant comprises 4 to 13 parts by weight of humectant.
The humectant provided by the invention comprises one or more of but not limited to glycerin, propylene glycol, 1, 3-propylene glycol, butanediol, hydroxyethyl urea, ceramide, sodium hyaluronate, levan, allantoin, luba oil, trehalose, sorbitol or betaine; the present invention is not limited in its source, and may be commercially available.
The whitening cosmetic provided by the invention comprises 0.01-0.1 part by weight of a chelating agent; preferably 0.02 to 0.08 parts by weight.
The chelating agent of the present invention includes, but is not limited to, EDTA-2 Na.
The whitening cosmetic provided by the invention comprises 0.1-10 parts by weight of an emulsifier; more preferably 1 to 9 parts by weight; most preferably 2 to 8 parts by weight.
Emulsifiers of the present invention include, but are not limited to, one or more of cetostearyl alcohol, cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, glyceryl stearate alcohol, polysorbates, alkyl glucosides, sodium stearyl glutamate, caprylic/capric triglyceride, or dimethicone. The present invention is not limited in its source, and may be commercially available.
The whitening cosmetic provided by the invention comprises 1-20 parts by weight of an emollient; preferably, the skin-care lotion comprises 2-18 parts by weight of an emollient; more preferably, the skin-care lotion comprises 3-17 parts by weight of an emollient; most preferably 4-16 parts by weight of an emollient.
The emollient provided by the invention comprises one or more of wheat germ oil, macadamia nut oil, jojoba oil, avocado oil, shea butter, sweet almond oil, coix seed oil, rice bran oil, safflower oil or myristyl myristate. The present invention is not limited in its source, and may be commercially available.
The whitening cosmetic provided by the invention comprises 0.0-5 parts by weight of a thickening agent; preferably 0.1 to 4.5 parts by weight of a thickener; more preferably, the thickener is included in an amount of 0.5 to 4 parts by weight.
The thickening agent comprises one or more of xanthan gum, carbomer, cellulose and modified substances thereof, polyacrylamide or sodium acrylate/sodium acryloyldimethyl taurate copolymer; the present invention is not limited in its source, and may be commercially available.
The whitening cosmetic provided by the invention comprises 0.01-0.1 part by weight of pH regulator; preferably comprises 0.02-0.09 parts by weight of pH regulator; more preferably 0.03 to 0.08 parts by weight.
The pH adjusting agent of the present invention includes, but is not limited to, one or both of citric acid or triethanolamine. The present invention is not limited in its source, and may be commercially available.
The pH value of the cosmetic is 5-7. The product of the cosmetic of the present invention may be in the form of, but not limited to, a mask, water, lotion, or cream. The preparation method comprises the specific preparation process and auxiliary materials, and is carried out conventionally.
The invention provides a preparation method of a whitening cosmetic in any one of the technical schemes, which comprises the following steps:
heating and mixing a solvent, a thickening agent and a humectant, and stirring to obtain a first mixture;
mixing the emollient and the emulsifier, and heating and stirring to obtain a second mixture;
homogenizing and emulsifying the first mixture and the second mixture, stirring, mixing with the composition and the preservative in any one of the technical schemes, stirring, and cooling to obtain the composition.
The method comprises the steps of heating and mixing a solvent, a thickening agent and a humectant, and stirring to obtain a first mixture.
The above components and proportions are clearly described in the present invention, and are not repeated herein.
Wherein the heating time is preferably 80-85 ℃; the stirring speed is preferably 1000-1200 r/min; the stirring time is 20-30 min; still standing for 20-30 min after stirring.
Mixing emollient and emulsifier, heating and stirring to obtain second mixture. Preferably mixing in an oil phase pot, wherein the temperature for heating and stirring is 80-90 ℃; the stirring speed is preferably 1000-1200 r/min; the stirring time is 20-30 min.
The above components and proportions are clearly described in the present invention, and are not repeated herein.
Homogenizing and emulsifying the first mixture and the second mixture, and stirring.
The emulsification is preferably carried out in an emulsification pot, and the emulsification and the stirring specifically comprise the following steps: homogenizing at 2000-3000 r/min for 8-10 min; then stirring for 15-20 minutes at the temperature of 1000 r/min.
Then mixing with the composition and the preservative in any one of the technical schemes, stirring and cooling to obtain the composition.
The mixing and stirring mode is not limited, and preferably the stirring speed is 1000-1200 r/min; the stirring time is 20-30 min.
And then cooling to 25-45 ℃. Discharging after the skin care product is qualified by inspection, and preparing the emulsion skin care product.
The invention provides a whitening composition which comprises the following raw materials in parts by weight: 0.5-8 parts of lactobacillus/rice fermentation product, 1-9 parts of green lemon fermentation raw pulp, 0.01-1.5 parts of truffle extract and 0.01-1 part of pomelo oil tea extract. The whitening composition is prepared by mixing the lactobacillus/rice fermentation product, the green lemon fermentation raw stock, the white truffle extract and the pomelo oil tea extract; the components of the whitening anti-aging active substance provided by the invention have the functions of mutual matching and synergistic interaction, and can obtain outstanding whitening and antioxidant effects.
In order to further illustrate the present invention, a whitening composition, a cosmetic and an application provided by the present invention will be described in detail with reference to examples.
Examples 1-3 preparation of whitening compositions
The whitening composition of the embodiment is prepared by mixing the following whitening active ingredients, and the specific parts by weight are detailed in table 1:
table 1:
the prepared composition is subjected to a whitening effect test, and the whitening effect test specifically comprises the following steps:
in vitro whitening test
1. The purpose of the test is as follows: tyrosinase inhibition comparisons were performed.
2. Test instrument and reagent
The main apparatus is as follows: spectrophotometer spectral GENESYS-5, Thermo corporation, USA;
the main reagents are as follows: tyrosinase (sigma, usa), the other reagents being conventional; the compositions of example 1, example 2, example 3, lactobacillus/rice fermentation products, lime fermented puree, white truffle extract and grapefruit oil tea extract of the present invention were formulated at 6% concentration.
3. Test method
Phosphate buffer (pH6.8, 0.1mol/L), sample solution, and tyrosine solution were added to each tube. Placing in 37 deg.C water bath for 10min, adding tyrosinase, reacting in 37 deg.C water bath for 10min, measuring absorbance value at 475nm, averaging for 3 times, and averaging.
The experimental system design is shown in table 2, C1 is blank control, C2 is used for blank zeroing, S1 is sample tube, and S2 is used for sample zeroing. The samples were example 1, example 2, example 3, lactobacillus/rice fermentation product, lime fermented puree, white truffle extract and grapefruit oil tea extract.
Tyrosinase inhibition ═ (blank absorbance value-sample absorbance value)/blank absorbance value × 100%.
TABLE 2 tyrosinase inhibition experiment system sample application Table
4. The test results are shown in Table 3.
TABLE 3 tyrosinase inhibition assay
In vitro test results show that the compositions of examples 1-3 of the invention have better tyrosinase inhibitory activity, and the inhibition rate is higher than that of each single-dose group.
Second, in vitro antioxidant test
Purpose of the experiment: the antioxidant effect of the plant extract composition was examined by in vitro tests.
Experimental materials: diphenylpicrylphenylhydrazine radical (abbreviation: DPPH, Sigma, USA); du800 uv-vis spectrophotometer (Beckman corporation, usa); the compositions prepared in examples 1-3, lactobacillus/rice fermentation product, lime fermented puree, white truffle extract, and grapefruit tea extract were formulated at a concentration of 6%.
The experimental method comprises the following steps: taking 0.1mL of sample solution, adding 2mL of 60 mu mol/L DPPH solution, uniformly mixing, standing for 30min, adjusting the zero point by using an original solvent, and measuring the absorbance at 515nm as Ai; uniformly mixing 0.1mL of solvent and 2mL of DPPH solution by the same method, and determining the absorbance as Ac; 0.1mL of the sample solution +2mL of the solvent were mixed and the absorbance was measured as Aj. The radical scavenging rate was calculated by the following formula.
The clearance (%) [1- (Ai-Aj)/Ac ] x 100%
Wherein Aj reflects the contribution of the sample itself to absorbance; absorbance values of Ai samples after action on DPPH; ac is the absorption of DPPH itself at the measurement wavelength. The results of the experiment are shown in table 4:
TABLE 4 antioxidant capacity test of plant extract composition
| Sample (I) | Clearance (%) |
| Example 1 composition | 93.2 |
| Example 1 composition | 94.9 |
| Example 1 composition | 96.3 |
| Lactobacillus/Rice fermentation product | 81.6 |
| Green lemon fermented raw stock | 83.7 |
| Truffle extract | 72.9 |
| Pomelo oil tea extract | 78.4 |
In vitro experiment results show that the compositions of examples 1 to 3 of the invention have better free radical scavenging capacity and higher scavenging rate than that of each single-dose group.
Examples 4 to 6
A whitening cosmetic composition containing whitening anti-aging composition is prepared into emulsion, and the contents of the raw material components, the comparative raw material components and the blank control components are shown in Table 5.
TABLE 5 examples 4 to 6, comparative examples 1 to 8 and blank group (unit: mass%)
The invention provides a preparation process method of the cosmetic emulsion containing the whitening composition, which is described as follows:
1) adding deionized water into a water pot, adding carbomer under rapid stirring, stirring for swelling, adding xanthan gum, 1, 3-propylene glycol, butanediol, EDTA-2NA and allantoin which are well dispersed in glycerol, heating to 80-85 ℃, stirring at 1200r/min for 20-30 min, and standing for 30min under heat preservation to obtain a mixed material A;
2) adding caprylic/capric triglyceride, isopropyl myristate and polydimethylsiloxane into an oil phase pot, heating to 80 ℃, keeping the temperature at 1200r/min, and stirring for 20min to obtain a mixed material B;
3) pumping the mixed material A and the mixed material B into an emulsifying pot, homogenizing at a high speed of 3000r/min for 8min, keeping the temperature at 1000r/min, stirring for 20min, cooling to 45 ℃, adding triethanolamine, dissolved whitening active substances and preservatives, stirring for 20min, cooling to room temperature, inspecting, discharging to obtain the emulsion skin care product.
Test example 2 evaluation of skin whitening efficacy by Effect verification
1. The tester: 120 healthy women (25-45 years old) divided into 12 groups of 10 persons each; each group used the same formulation.
2. Test area: face (left face blank, right face comparative sample or example sample);
3. use of: twice a day in the morning and evening for 4 weeks
4. Testing an instrument: delfin SkinColorCatch (Finland)
5. The effect indexes are as follows: the change in color brightness (Δ L), ITA degree, and the L value (brightness) and ITA degree (color individual type angle) were measured and mainly used as indices.
Equation (1): Δ L ═ L (after 1 month of test on control or example product) -L (before the start of test) ] - [ L ═ L (after 1 month of test on blank) -L (before the start of test) h
ΔL*Average value of Δ L in each group
(2): ITA degree (representing the overall change of chromaticity, the larger the ITA degree value is, the lighter the skin color is.)
TABLE 6
| ITA degree range | Skin color classification |
| 55-90 | Very shallow Very light |
| 41-54 | Light shallow |
| 28-40 | Intermediate, etc |
| 10-27 | Tanned tanning |
| -30-9 | Brown color of Brown |
| -90--29-29 | Dark color of Dark |
ITA degree (front)Mean values for each group (mean value for each group is 30) before the start of the test;
ITA degree (rear)Average values for each group after 1 month of testing on product.
6. The test results are shown in table 7 below:
TABLE 7
As can be seen from the results in table 7, the whitening and anti-aging composition of the present invention has more obvious whitening and skin color brightening effects through the synergistic effect of the functional components, and the whitening and anti-aging composition has more obvious effects than the composition lacking any whitening component.
Safety test
1. The number of tested persons: 30 persons in total, 3 men and 27 women; minimum age: 24 years old, maximum age: age 45 years old; mean age 35.73 ± 7.15 years volunteer enrollment criteria.
2. The test method comprises the following steps: examples 4-6 were tested for patch. Selecting a qualified spot tester, placing about 0.020-0.025 mL of a tested object into the spot tester by using a closed spot test method, externally applying a medical adhesive tape to the back of the tested object, removing the tested object after 24 hours, observing skin reactions 0.5, 24 and 48 hours after the spot is removed, and recording the results according to the skin reaction grading standard in technical Specification for cosmetic safety (2015 edition).
3. The evaluation criteria are as follows in table 8:
TABLE 8 grading Standard of adverse skin reactions
The result of the human skin closed patch test shows that 0 of 30 persons has positive reaction, and the test object does not cause adverse skin reaction to the batch of test objects according to the regulation in technical Specification for cosmetic safety (2015 edition).
Stability test
1. Stability test samples: example 6 whitening skin care essence product.
2. The test method comprises the following steps: the internal control standard (illumination for 1 month and high and low temperature test for 3 months) is higher than the national standard and the industrial standard.
3. The test results are shown in table 9 below.
TABLE 9
The results of the whitening skin care essence product of example 6 by stability test are shown in table 9: the whitening emulsion disclosed by the invention has good stability. In addition, the stability test results of the examples 4 and 5 are qualified and have better stability by the same test method.
The results show that: the composition has good stability in product application.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. The whitening composition is characterized by comprising the following raw materials in parts by weight:
0.5-8 parts of lactobacillus/rice fermentation product, 1-9 parts of green lemon fermentation raw pulp, 0.01-1.5 parts of truffle extract and 0.01-1 part of pomelo oil tea extract.
2. The composition of claim 1, wherein the whitening composition comprises the following raw materials in parts by weight:
1-7 parts of lactobacillus/rice fermentation product, 2-8 parts of green lemon fermentation raw stock, 0.1-1.3 parts of truffle extract and 0.1-0.9 part of pomelo oil tea extract.
3. The composition of claim 1, wherein the whitening composition comprises the following raw materials in parts by weight:
2-6 parts of lactobacillus/rice fermentation product, 3-7 parts of green lemon fermentation raw stock, 0.2-1.2 parts of truffle extract and 0.2-0.8 part of pomelo oil tea extract.
4. Use of the whitening composition of any one of claims 1 to 3 for the preparation of a cosmetic.
5. A whitening cosmetic comprising the composition of any one of claims 1 to 3 and an auxiliary material acceptable in the field of cosmetics.
6. The cosmetic according to claim 6, comprising a preservative, a solvent and the following components:
0.5 to 25 parts by weight of the composition according to any one of claims 1 to 3;
7. the cosmetic according to claim 5, wherein the humectant is selected from one or more of glycerin, propylene glycol, 1, 3-propylene glycol, butylene glycol, hydroxyethyl urea, ceramide, sodium hyaluronate, levan, allantoin, luba oil, trehalose, sorbitol, or betaine;
the emulsifier is one or more selected from cetostearyl alcohol, cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, glyceryl stearate alcohol, polysorbates, alkyl glucosides or sodium stearyl glutamate;
the emollient is selected from one or more of wheat germ oil, macadamia nut oil, jojoba oil, avocado oil, shea butter, sweet almond oil, Coicis semen oil, rice bran oil, safflower oil or myristyl myristate;
the thickener is selected from one or more of xanthan gum, carbomer, cellulose and modified substances thereof, polyacrylamide or sodium acrylate/sodium acryloyldimethyl taurate copolymer;
the pH regulator is one or two of citric acid and triethanolamine.
8. The cosmetic according to claim 5, wherein the pH of the cosmetic is 5 to 7.
9. The cosmetic of claim 5, wherein the product is in the form of a mask, water, lotion, or cream.
10. A method for preparing the whitening cosmetic according to any one of claims 5 to 9, comprising:
heating and mixing a solvent, a thickening agent and a humectant, and stirring to obtain a first mixture;
mixing the emollient and the emulsifier, and heating and stirring to obtain a second mixture;
homogenizing and emulsifying the first mixture and the second mixture, stirring, mixing with the composition of any one of claims 1 to 3 and the preservative, stirring, and cooling.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112675098A (en) * | 2021-02-02 | 2021-04-20 | 广东梵蜜琳生物科技有限公司 | Smoothing toner containing composition for regulating time rhythm and preparation method thereof |
| CN113616570A (en) * | 2021-08-18 | 2021-11-09 | 广州斑消宝化妆品有限公司 | Moisturizing and anti-wrinkle liquid and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104586735A (en) * | 2014-12-09 | 2015-05-06 | 美嘉乐(上海)生物科技有限公司 | Method for preparing fermented product filtrate by fermenting rice with lactobacillus casei, and application of fermented product filtrate |
| CN104666237A (en) * | 2015-02-12 | 2015-06-03 | 广州悦目生物科技有限公司 | Preparation method and application of truffle active ingredient |
| CN108578327A (en) * | 2018-07-15 | 2018-09-28 | 海南侯臣生物科技有限公司 | A kind of mountain shaddock moisture saver mask and preparation method thereof |
| CN108619058A (en) * | 2018-07-04 | 2018-10-09 | 界首市众鑫科技服务有限公司 | A kind of beautifying liquid of whitening antioxidation |
| CN108721155A (en) * | 2017-04-14 | 2018-11-02 | Isp投资有限公司 | Reveal the cosmetics prepared product and its cosmetic method of extract containing kahikatea |
| TWI674101B (en) * | 2018-07-12 | 2019-10-11 | 弘光科技大學 | Method for preparing lemon fermentation product and use thereof |
-
2020
- 2020-07-31 CN CN202010759763.XA patent/CN111700849A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104586735A (en) * | 2014-12-09 | 2015-05-06 | 美嘉乐(上海)生物科技有限公司 | Method for preparing fermented product filtrate by fermenting rice with lactobacillus casei, and application of fermented product filtrate |
| CN104666237A (en) * | 2015-02-12 | 2015-06-03 | 广州悦目生物科技有限公司 | Preparation method and application of truffle active ingredient |
| CN108721155A (en) * | 2017-04-14 | 2018-11-02 | Isp投资有限公司 | Reveal the cosmetics prepared product and its cosmetic method of extract containing kahikatea |
| CN108619058A (en) * | 2018-07-04 | 2018-10-09 | 界首市众鑫科技服务有限公司 | A kind of beautifying liquid of whitening antioxidation |
| TWI674101B (en) * | 2018-07-12 | 2019-10-11 | 弘光科技大學 | Method for preparing lemon fermentation product and use thereof |
| CN108578327A (en) * | 2018-07-15 | 2018-09-28 | 海南侯臣生物科技有限公司 | A kind of mountain shaddock moisture saver mask and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112675098A (en) * | 2021-02-02 | 2021-04-20 | 广东梵蜜琳生物科技有限公司 | Smoothing toner containing composition for regulating time rhythm and preparation method thereof |
| CN113616570A (en) * | 2021-08-18 | 2021-11-09 | 广州斑消宝化妆品有限公司 | Moisturizing and anti-wrinkle liquid and preparation method thereof |
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Application publication date: 20200925 |