CN105287320A - Mild lifting and repairing eye cream and preparation method thereof - Google Patents
Mild lifting and repairing eye cream and preparation method thereof Download PDFInfo
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- CN105287320A CN105287320A CN201510898184.2A CN201510898184A CN105287320A CN 105287320 A CN105287320 A CN 105287320A CN 201510898184 A CN201510898184 A CN 201510898184A CN 105287320 A CN105287320 A CN 105287320A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention belongs to the technical field of cosmetics, and particularly relates to mild lifting and repairing eye cream and a preparation method thereof. The eye cream is prepared from retinyl palmitate and palmitoyl oligopeptide, preferably retinyl palmitate, palmitoyl oligopeptide, astragalus membranaceus root extract, rhizoma atractylodis macrocephalae extract and bupleurum falcatum root extract. The composition is prepared on the basis of screening. Researches indicate that the composition has good effects of relieving skin wrinkles and the like, and is added into substrate to prepare eye cream. The eye cream has mild, lifting and repairing effects, and has good stability.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of gentle eye treatment cream and preparation method thereof.
Background technology
Eye skin is the thinnest skin of human body, again activity position the most frequently simultaneously, but also be pull the maximum place of skin number of times in making up, be very easy to grow wrinkle, and be just difficult to disappear once grow, the FAQs of eye has following: black eye, eye pouch, edema, microgroove, dry stricture of vagina, crows-feet, fat granule, eyes lack expression etc.The eyes are the windows of the mind, but this fan window is very fragile, and the even brows that smile are knitted tightly, and eyes all can be made to have relaxed the double stricture of vagina of losing face of eye pouch.Think that eyes are outstanding charming, make instant soft and smooth the becoming clear of eyes skin become electric eye goddess, certainly will give eyes All-round Nursing care.
Eye cream, one of skin type cosmetic product.There is moist effect, except can lowering black eye, eye pouch problem, also possess the effect improving wrinkle, microgroove simultaneously.Eye cream is used to this thinner one deck skin of protection around eyes, have certain effectiveness, but different eye creams has different effects to eye pouch, black eye, crows-feet etc.The kind of eye cream is a lot, is roughly divided into eye mask, eye glue, eye gel, eye sticker, eye cream etc.; Functionally be divided into moist eye cream, consolidation eye cream, aging resistance eye cream, antiallergic eye cream etc.The eye cream that existing market is sold absorbs bad, and functional effect is not obvious; Even cause some bad reflections such as oils and fats grain, allergy.Therefore, research and develop a kind of new eye cream, allow consumer have more selection.
Summary of the invention
For these reasons, applicant, through years of researches, obtains a kind of new eye cream, the composition containing the maintenance eye part skin that compacts in eye cream of the present invention, and this composition comprises: retinyl palmitate, palmitoyl oligopeptide; Preferably the composition of maintenance eye part skin is further: retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract; Above-mentioned composition obtains on screening basis, and research shows, compositions of the present invention has well dispels the effects such as wrinkle of skin, adds in substrate and is prepared into eye cream, has gentleness, compacts, the effect of maintenance to eyes skin; Eye cream of the present invention has better stability.
The present invention is achieved through the following technical solutions.
A kind of eye cream, comprising: retinyl palmitate, palmitoyl oligopeptide.
Wherein retinyl palmitate 0.4-0.6 weight portion, palmitoyl oligopeptide 0.0001 weight portion.
Eye cream also comprises Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract.
Preferred eye cream comprises: retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract.
Described eye cream is preferred: retinyl palmitate 0.4-0.6 weight portion, palmitoyl oligopeptide 0.0001 weight portion, Radix Astragali root extract 0.1-0.3 weight portion, Rhizoma Atractylodis Macrocephalae root extract 0.1-0.3 weight portion, Bupleurum krylovianum root extract 0.1-0.3 weight portion.
The compositions of described retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract and Bupleurum krylovianum root extract is in the application in maintenance eye part skin cosmetics of compacting.
Described eye cream raw material comprises: glycerol, Butyrospermum parkii fruit fat, 1,3-PD, squalane, vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer, polydimethylsiloxane, Jojoba esters, dicaprylyl carbonate, behenyl alcohol, cetearyl alcohol, glyceryl stearate SE, Palmic acid, hydroxyethyl-cellulose, stearic acid, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, Tridocosanoin, 1,3 butylene glycol, decyl glucoside, carbomer, xanthan gum, phenoxyethanol, Sensiva SC50, two (lauramide glutamine) L-Lysine sodium salt, 1,2-hexanediol, sodium hydroxide, tocopherol, hyaluronate sodium, sodium lactate, caprylyl glycol, polysorbate-20, resveratrol, spermol, macadimia nut seed oil, hydrolysis Lac regis apis albumen, octyl dodecanol lauroyl glutamate ester, myristyl alcohol, Palmitoyl Tetrapeptide-7, phytosphingosine, Cer AP II, ceramide 3, cholesterol, denatonium benzoate, Cer EOS, retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract.
Described eye cream raw material comprises: glycerol 8-10 weight portion, Butyrospermum parkii fruit fat 5-7 weight portion, 1,3-PD 4-6 weight portion, squalane 3-5 weight portion, vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer 2-4 weight portion, polydimethylsiloxane 2-4 weight portion, Jojoba esters 2-4 weight portion, dicaprylyl carbonate 1-3 weight portion, behenyl alcohol 0.5-1.5 weight portion, cetearyl alcohol 0.5-1.5 weight portion, glyceryl stearate SE0.5-1.5 weight portion, Palmic acid 0.5-0.7 weight portion, hydroxyethyl-cellulose 0.4-0.6 weight portion, stearic acid 0.3-0.5 weight portion, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.3-0.5 weight portion, Tridocosanoin 0.3-0.5 weight portion, 1,3 butylene glycol 0.2-0.4 weight portion, decyl glucoside 0.2-0.3 weight portion, carbomer 0.1-0.3 weight portion, xanthan gum 0.1-0.3 weight portion, phenoxyethanol 0.05-0.15 weight portion, Sensiva SC50 0.05-0.15 weight portion, two (lauramide glutamine) L-Lysine sodium salt 0.08-0.1 weight portion, 1,2-hexanediol 0.07-0.08 weight portion, sodium hydroxide 0.06-0.08 weight portion, tocopherol 0.06-0.07 weight portion, hyaluronate sodium 0.04-0.06 weight portion, sodium lactate 0.01 weight portion, caprylyl glycol 0.025 weight portion, polysorbate-200.005 weight portion, resveratrol 0.005 weight portion, spermol 0.004 weight portion, macadimia nut seed oil 0.0015 weight portion, hydrolysis Lac regis apis albumen 0.001-0.0015 weight portion, octyl dodecanol lauroyl glutamate ester 0.001 weight portion, myristyl alcohol 0.001 weight portion, Palmitoyl Tetrapeptide-70.00005 weight portion, phytosphingosine 0.000025 weight portion, Cer AP II0.000025 weight portion, ceramide 3 0.000025 weight portion, cholesterol 0.000025 weight portion, denatonium benzoate 0.00002 weight portion, Cer EOS 0.0000005 weight portion, retinyl palmitate 0.4-0.6 weight portion, palmitoyl oligopeptide 0.0001 weight portion, Radix Astragali root extract 0.1-0.3 weight portion, Rhizoma Atractylodis Macrocephalae root extract 0.1-0.3 weight portion, Bupleurum krylovianum root extract 0.1-0.3 weight portion.
The preparation method of described eye cream is:
(1) water intaking, glycerol, 1,3-PD, two (lauramide glutamine) L-Lysine sodium salt, 1,3 butylene glycol, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane, Jojoba esters, tocopherol, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer, vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer, water, decyl glucoside, retinyl palmitate, tocopherol, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol, water, 1, 3-butanediol, carbomer, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol, hydrolysis Lac regis apis albumen, 1, ammediol, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt, squalane, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Following is purchase producer and the lot number of part material of the present invention:
Detailed description of the invention
Below in conjunction with example, the present invention is elaborated.Following examples do not limit protection scope of the present invention.
Following test, be on the basis of repeatedly creative test, for the claimed content of the present invention, the concluding of carrying out is tested.
One, screening test: anti aging effect is tested
Test 1 group: retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g.
Test 2 groups: retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g.
Test 3 groups: retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
Test 4 groups: retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Rhizoma Atractylodis Macrocephalae root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
Test 5 groups: retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g, Rhizoma Atractylodis Macrocephalae root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
Sample preparation: get above-mentioned test group raw material, add 100mL deionized water, then add 100mL1,3-butanediol, mix homogeneously, for subsequent use.
Test method: get healthy 1 monthly age male nude mouse, body weight 14 ± 2g, random packet: model group, test 1 group-test 5 groups, model group: every day neck dorsal sc injection D-galactose 1000mg/kg, and in conjunction with long wavelength (365nm) and short wavelength (254nm) ultraviolet radiation skin of back, UVA cumulative exposure intensity is 260J/cm
2, short wavelength's cumulative exposure intensity 6.5J/cm
2, test group: injection and the same model group of illumination, injection and illumination basis on, test specimen is smeared again to back, every day 2 times, each 2mL, continuously injection and illumination 6 weeks, model group is slow in action, back wrinkle is obvious, in obvious old and feeble sign, puts to death bark fetching and carry out Biochemical Indexes after drug withdrawal 2d, Biochemical Indexes method: remove every nude mice back skin tissues block about 1g according to component, through normal saline rinsing, with operation to dispelling subcutaneous fat and other connective tissues, filter paper blots, weigh, precision takes the normal saline of skin histology 9 times amount, being poured into by the normal saline of 2/3 amount is equipped with in the mortar of piece of tissue, rear grinding is shredded with ophthalmology is little, be ground to till can't see massive texture, thick homogenate is poured in small beaker, with the clean mortar of the normal saline flushing of residue 1/3, 3min is pulverized continuously by small beaker Ultrasonic Pulverization instrument ice bath, then multigelation 3 times, cellular content is free in liquid phase completely, by tissue homogenate at the centrifugal 15min of 3500r/min, get supernatant to measure, according to SOD, HYP and MDA test kit description method measures.
Result of the test: in table 1.
Table 1 nude mice skin organizes the measurement result of mesophytization
Note: compare * * P<0.01 with model group, * P<0.05.
Conclusion (of pressure testing): above-mentioned test shows, retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract and Bupleurum krylovianum root extract compositions can be good at preventing skin aging, have the effect of anti aging effect.
Two, demonstration test:
Test 1 group: glycerol 8g, Butyrospermum parkii fruit fat 5g, 1,3-PD 4g, squalane 3g, polymethyl siloxane silsesquioxane cross linked polymer 2g, polydimethylsiloxane 2g, Jojoba esters 2g, dicaprylyl carbonate 1g, behenyl alcohol 0.5g, cetearyl alcohol 0.5g, glyceryl stearate 0.5g, Palmic acid 0.5g, hydroxyethyl-cellulose 0.4g, stearic acid 0.3g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.3g, Tridocosanoin 0.3g, 1,3 butylene glycol 0.2g, decyl glucoside 0.2g, carbomer 0.1g, xanthan gum 0.1g, phenoxyethanol 0.05g, Sensiva SC50 0.05g, two (lauramide glutamine) L-Lysine sodium salt 0.08g, 1,2-hexanediol 0.07g, sodium hydroxide 0.06g, tocopherol 0.06g, hyaluronate sodium 0.04g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.001g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.4g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.1g, Rhizoma Atractylodis Macrocephalae root extract 0.1g, Bupleurum krylovianum root extract 0.1g.
The preparation method of eye cream is:
(1) fetch water 34g, glycerol 1.3g, 1, ammediol 1g, two (lauramide glutamine) L-Lysine sodium salt 0.03g, 1,3-butanediol 0.1g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.03g, polymethyl siloxane silsesquioxane cross linked polymer, water 7g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 6.7g, water 9.8g, 1, 3-butanediol 0.1g, carbomer 0.07g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.02g, hydrolysis Lac regis apis albumen, 1, ammediol 3g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.05g, squalane 2g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Test 2 groups: glycerol 9g, Butyrospermum parkii fruit fat 6g, 1,3-PD 5g, squalane 4g, vinyldimethicone 3g, polydimethylsiloxane 3g, Jojoba esters 3g, dicaprylyl carbonate 2g, behenyl alcohol 1g, cetearyl alcohol 1g, glyceryl stearate SE1g, Palmic acid 0.6g, hydroxyethyl-cellulose 0.5g, stearic acid 0.4g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.4g, Tridocosanoin 0.4g, 1,3 butylene glycol 0.3g, decyl glucoside 0.25g part, carbomer 0.2g, xanthan gum 0.2g, phenoxyethanol 0.1g, Sensiva SC50 0.1g, two (lauramide glutamine) L-Lysine sodium salt 0.09g, 1,2-hexanediol 0.075g, sodium hydroxide 0.07g, tocopherol 0.065g, hyaluronate sodium 0.05g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.0012g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g, Rhizoma Atractylodis Macrocephalae root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
The preparation method of eye cream is:
(1) fetch water 38g, glycerol 1.5g, 1, ammediol 1.3g, two (lauramide glutamine) L-Lysine sodium salt 0.035g, 1,3-butanediol 0.15g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1.5g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.06g, vinyldimethicone, water 8.5g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 7.5g, water 11.2g, 1, 3-butanediol 0.15g, carbomer 0.14g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.025g, hydrolysis Lac regis apis albumen, 1, ammediol 3.7g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.055g, squalane 2.5g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Test 3 groups: glycerol 10g, Butyrospermum parkii fruit fat 7g, 1,3-PD 6g, squalane 5g, vinyldimethicone 4g, polydimethylsiloxane 4g, Jojoba esters 4g, dicaprylyl carbonate 3g, behenyl alcohol 1.5g, cetearyl alcohol 1.5g, glyceryl stearate SE1.5g, Palmic acid 0.7g, hydroxyethyl-cellulose 0.6g, stearic acid 0.5g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.5g, Tridocosanoin 0.5g, 1,3 butylene glycol 0.4g, decyl glucoside 0.3g, carbomer 0.3g, xanthan gum 0.3g, phenoxyethanol 0.15g, Sensiva SC50 0.15g, two (lauramide glutamine) L-Lysine sodium salt 0.1g, 1,2-hexanediol 0.08g, sodium hydroxide 0.08g, tocopherol 0.07g, hyaluronate sodium 0.06g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.0015g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.6g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.3g, Rhizoma Atractylodis Macrocephalae root extract 0.3g, Bupleurum krylovianum root extract 0.3g.
(1) fetch water 41g, glycerol 1.8g, 1, ammediol 1.5g, two (lauramide glutamine) L-Lysine sodium salt 0.04g, 1,3-butanediol 0.2g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1.8g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.12g, vinyldimethicone, water 11g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 8.2g, water 14.5g, 1, 3-butanediol 0.2g, carbomer 0.18g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.03g, hydrolysis Lac regis apis albumen, 1, ammediol 4.5g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.06g, squalane 3.2g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Test method: healthy women volunteer, 29 ~ 45 years old age, average (38.10 ± 5.35) year, random packet, often organizes 10 women; Inform that volunteer smears eye cream according to correct maneuver after sooner or later cleaning face every day.Eye cream was weighed in 0th, 4 weeks in test, measure keratodermatitis water content, measure skin around eyes elasticity.During mensuration indices, room temperature is 20 DEG C ~ 25 DEG C, and humidity is 35% ~ 70%, and requires that experimenter shifts to an earlier date 30min and enters test environment, carries out the measurement of each index after rest.Moisture of skin tester (Courage+KhazakaCM825, Germany) is according to the water content that can reflect in keratodermatitis of capacitance, and water content of stratum corneum is higher, and its capacitance is also higher; Vice versa.This instrument is believed to accurate detection of skin cuticlar water content.Skin elasticity is tested: adopt skin elasticity tester CutometerMPA580, German Courage+Khazaka company.Carry out maintenance and the calibration of instrument before test, test period apparatus working is normal.Test zone parallel assay 3 times during measurement, get its meansigma methods.
Result of the test: in table 2, table 3.
Table 2 different tests group moistening effect
| Group | Water content of stratum corneum the 0th week | Water content of stratum corneum the 4th week |
| Test 1 group | 61.07±9.52 | 67.20±7.43* |
| Test 2 groups | 60.49±9.10 | 70.25±6.90* |
| Test 3 groups | 60.37±8.54 | 68.22±7.17* |
Note: compared * P<0.05 with the 0th week.
Table 3 different tests group skin elasticity test effect
| Group | Water content of stratum corneum the 0th week | Water content of stratum corneum the 4th week |
| Test 1 group | 58.47±6.25 | 72.08±4.48** |
| Test 2 groups | 59.92±5.80 | 73.94±5.27** |
| Test 3 groups | 60.10±5.74 | 72.09±5.09** |
Note: compared * * P<0.05 with the 0th week, * P<0.05.
Conclusion (of pressure testing): above-mentioned test shows, the present composition joins in substrate and is prepared into eye cream, has good moisture-keeping function, strengthens the elasticity of skin, thus reaches the effect of maintenance of compacting to skin around eyes.
Three, stability test
Test 1 group: glycerol 9g, Butyrospermum parkii fruit fat 6g, 1,3-PD 5g, squalane 4g, vinyldimethicone 3g, polydimethylsiloxane 3g, Jojoba esters 3g, dicaprylyl carbonate 2g, behenyl alcohol 1g, cetearyl alcohol 1g, glyceryl stearate SE1g, Palmic acid 0.6g, hydroxyethyl-cellulose 0.5g, stearic acid 0.4g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.4g, Tridocosanoin 0.4g, 1,3 butylene glycol 0.3g, decyl glucoside 0.25g part, carbomer 0.2g, xanthan gum 0.2g, phenoxyethanol 0.1g, Sensiva SC50 0.1g, two (lauramide glutamine) L-Lysine sodium salt 0.09g, 1,2-hexanediol 0.075g, sodium hydroxide 0.07g, tocopherol 0.065g, hyaluronate sodium 0.05g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.0012g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g, Rhizoma Atractylodis Macrocephalae root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
The preparation method of eye cream is:
(1) fetch water 38g, glycerol 1.5g, 1, ammediol 1.3g, two (lauramide glutamine) L-Lysine sodium salt 0.035g, 1,3-butanediol 0.15g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1.5g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.06g, vinyldimethicone, water 8.5g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 7.5g, water 11.2g, 1, 3-butanediol 0.15g, carbomer 0.14g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.025g, hydrolysis Lac regis apis albumen, 1, ammediol 3.7g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.055g, squalane 2.5g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Test 2 groups: glycerol 9g, Butyrospermum parkii fruit fat 6g, 1,3-PD 5g, squalane 4g, vinyldimethicone 3g, polydimethylsiloxane 3g, Jojoba esters 3g, dicaprylyl carbonate 2g, behenyl alcohol 1g, cetearyl alcohol 1g, glyceryl stearate SE1g, Palmic acid 0.6g, hydroxyethyl-cellulose 0.5g, stearic acid 0.4g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.4g, Tridocosanoin 0.4g, 1,3 butylene glycol 0.3g, decyl glucoside 0.25g part, carbomer 0.2g, phenoxyethanol 0.1g, Sensiva SC50 0.1g, two (lauramide glutamine) L-Lysine sodium salt 0.09g, 1,2-hexanediol 0.075g, sodium citrate 0.21g, tocopherol 0.065g, hyaluronate sodium 0.05g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.0012g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g, Rhizoma Atractylodis Macrocephalae root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
The preparation method of eye cream is:
(1) fetch water 38g, glycerol 1.5g, 1, ammediol 1.3g, two (lauramide glutamine) L-Lysine sodium salt 0.035g, 1,3-butanediol 0.15g, hydroxyethyl-cellulose, sodium citrate, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1.5g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.06g, vinyldimethicone, water 8.5g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 7.5g, water 11.2g, 1, 3-butanediol 0.15g, carbomer 0.14g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.025g, hydrolysis Lac regis apis albumen, 1, ammediol 3.7g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.055g, squalane 2.5g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Whether whether test method: get eye cream, is placed in 40 DEG C and deposits 24h, deposit 24h, then deposit 24h in-5 DEG C in room temperature, circulates 3 times successively, observe and have layering, oil slick, color and luster to change.
Conclusion (of pressure testing): in table 4.
Table 4 stability test result
| Group | Whether layering | Whether oil slick | Whether color and luster changes |
| Test 1 group | No | No | No |
| Test 2 groups | Have | No | Have |
Conclusion (of pressure testing): removed by xanthan gum in eye cream prescription, after changing sodium hydroxide into sodium citrate, after cold cycling, there is layering and color and luster change, thus cause eye cream off quality, absolutely prove that eye cream prescription of the present invention has scientific meaning in eye cream simultaneously.
Preparation embodiment
Embodiment 1
Eye cream prescription is: glycerol 8g, Butyrospermum parkii fruit fat 5g, 1,3-PD 4g, squalane 3g, polymethyl siloxane silsesquioxane cross linked polymer 2g, polydimethylsiloxane 2g, Jojoba esters 2g, dicaprylyl carbonate 1g, behenyl alcohol 0.5g, cetearyl alcohol 0.5g, glyceryl stearate 0.5g, Palmic acid 0.5g, hydroxyethyl-cellulose 0.4g, stearic acid 0.3g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.3g, Tridocosanoin 0.3g, 1,3 butylene glycol 0.2g, decyl glucoside 0.2g, carbomer 0.1g, xanthan gum 0.1g, phenoxyethanol 0.05g, Sensiva SC50 0.05g, two (lauramide glutamine) L-Lysine sodium salt 0.08g, 1,2-hexanediol 0.07g, sodium hydroxide 0.06g, tocopherol 0.06g, hyaluronate sodium 0.04g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.001g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.4g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.1g, Rhizoma Atractylodis Macrocephalae root extract 0.1g, Bupleurum krylovianum root extract 0.1g.
The preparation method of eye cream is:
(1) fetch water 34g, glycerol 1.3g, 1, ammediol 1g, two (lauramide glutamine) L-Lysine sodium salt 0.03g, 1,3-butanediol 0.1g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.03g, polymethyl siloxane silsesquioxane cross linked polymer, water 7g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 6.7g, water 9.8g, 1, 3-butanediol 0.1g, carbomer 0.07g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.02g, hydrolysis Lac regis apis albumen, 1, ammediol 3g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.05g, squalane 2g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Embodiment 2
Eye cream prescription is: glycerol 9g, Butyrospermum parkii fruit fat 6g, 1,3-PD 5g, squalane 4g, vinyldimethicone 3g, polydimethylsiloxane 3g, Jojoba esters 3g, dicaprylyl carbonate 2g, behenyl alcohol 1g, cetearyl alcohol 1g, glyceryl stearate SE1g, Palmic acid 0.6g, hydroxyethyl-cellulose 0.5g, stearic acid 0.4g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.4g, Tridocosanoin 0.4g, 1,3 butylene glycol 0.3g, decyl glucoside 0.25g part, carbomer 0.2g, xanthan gum 0.2g, phenoxyethanol 0.1g, Sensiva SC50 0.1g, two (lauramide glutamine) L-Lysine sodium salt 0.09g, 1,2-hexanediol 0.075g, sodium hydroxide 0.07g, tocopherol 0.065g, hyaluronate sodium 0.05g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.0012g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.5g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.2g, Rhizoma Atractylodis Macrocephalae root extract 0.2g, Bupleurum krylovianum root extract 0.2g.
The preparation method of eye cream is:
(1) fetch water 38g, glycerol 1.5g, 1, ammediol 1.3g, two (lauramide glutamine) L-Lysine sodium salt 0.035g, 1,3-butanediol 0.15g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1.5g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.06g, vinyldimethicone, water 8.5g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 7.5g, water 11.2g, 1, 3-butanediol 0.15g, carbomer 0.14g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.025g, hydrolysis Lac regis apis albumen, 1, ammediol 3.7g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.055g, squalane 2.5g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Embodiment 3
Eye cream prescription is: glycerol 10g, Butyrospermum parkii fruit fat 7g, 1,3-PD 6g, squalane 5g, vinyldimethicone 4g, polydimethylsiloxane 4g, Jojoba esters 4g, dicaprylyl carbonate 3g, behenyl alcohol 1.5g, cetearyl alcohol 1.5g, glyceryl stearate SE1.5g, Palmic acid 0.7g, hydroxyethyl-cellulose 0.6g, stearic acid 0.5g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.5g, Tridocosanoin 0.5g, 1,3 butylene glycol 0.4g, decyl glucoside 0.3g, carbomer 0.3g, xanthan gum 0.3g, phenoxyethanol 0.15g, Sensiva SC50 0.15g, two (lauramide glutamine) L-Lysine sodium salt 0.1g, 1,2-hexanediol 0.08g, sodium hydroxide 0.08g, tocopherol 0.07g, hyaluronate sodium 0.06g, sodium lactate 0.01g, caprylyl glycol 0.025g, polysorbate-200.005g, resveratrol 0.005g, spermol 0.004g, macadimia nut seed oil 0.0015g, hydrolysis Lac regis apis albumen 0.0015g, octyl dodecanol lauroyl glutamate ester 0.001g, myristyl alcohol 0.001g, Palmitoyl Tetrapeptide-70.00005g, phytosphingosine 0.000025g, Cer AP II0.000025g, ceramide 3 0.000025g, cholesterol 0.000025g, denatonium benzoate 0.00002g, Cer EOS 0.0000005g, retinyl palmitate 0.6g, palmitoyl oligopeptide 0.0001g, Radix Astragali root extract 0.3g, Rhizoma Atractylodis Macrocephalae root extract 0.3g, Bupleurum krylovianum root extract 0.3g.
(1) fetch water 41g, glycerol 1.8g, 1, ammediol 1.5g, two (lauramide glutamine) L-Lysine sodium salt 0.04g, 1,3-butanediol 0.2g, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane 1.8g, Jojoba esters, tocopherol 0.02g, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer 0.12g, vinyldimethicone, water 11g, decyl glucoside, retinyl palmitate, tocopherol 0.02g, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol 8.2g, water 14.5g, 1, 3-butanediol 0.2g, carbomer 0.18g, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol 0.03g, hydrolysis Lac regis apis albumen, 1, ammediol 4.5g, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt 0.06g, squalane 3.2g, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
Preparation embodiment includes but not limited to above-mentioned.
Claims (9)
1. an eye cream, is characterized in that eye cream comprises: retinyl palmitate, palmitoyl oligopeptide.
2. a kind of eye cream according to claim 1, wherein retinyl palmitate 0.4-0.6 weight portion, palmitoyl oligopeptide 0.0001 weight portion.
3. a kind of eye cream according to claim 1, wherein eye cream comprises Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract.
4. a kind of eye cream according to claim 1 and 3, is characterized in that eye cream comprises: retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract.
5. a kind of eye cream according to claim 4, wherein retinyl palmitate 0.4-0.6 weight portion, palmitoyl oligopeptide 0.0001 weight portion, Radix Astragali root extract 0.1-0.3 weight portion, Rhizoma Atractylodis Macrocephalae root extract 0.1-0.3 weight portion, Bupleurum krylovianum root extract 0.1-0.3 weight portion.
6. a kind of eye cream according to claim 5, is characterized in that the compositions of retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract and Bupleurum krylovianum root extract is in the application in maintenance eye part skin cosmetics of compacting.
7. a kind of eye cream according to claim 3, eye cream raw material comprises: glycerol, Butyrospermum parkii fruit fat, 1,3-PD, squalane, vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer, polydimethylsiloxane, Jojoba esters, dicaprylyl carbonate, behenyl alcohol, cetearyl alcohol, glyceryl stearate SE, Palmic acid, hydroxyethyl-cellulose, stearic acid, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, Tridocosanoin, 1,3 butylene glycol, decyl glucoside, carbomer, xanthan gum, phenoxyethanol, Sensiva SC50, two (lauramide glutamine) L-Lysine sodium salt, 1,2-hexanediol, sodium hydroxide, tocopherol, hyaluronate sodium, sodium lactate, caprylyl glycol, polysorbate-20, resveratrol, spermol, macadimia nut seed oil, hydrolysis Lac regis apis albumen, octyl dodecanol lauroyl glutamate ester, myristyl alcohol, Palmitoyl Tetrapeptide-7, phytosphingosine, Cer AP II, ceramide 3, cholesterol, denatonium benzoate, Cer EOS, retinyl palmitate, palmitoyl oligopeptide, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract.
8. a kind of eye cream according to claim 3, eye cream raw material comprises: glycerol 8-10 weight portion, Butyrospermum parkii fruit fat 5-7 weight portion, 1,3-PD 4-6 weight portion, squalane 3-5 weight portion, vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer 2-4 weight portion, polydimethylsiloxane 2-4 weight portion, Jojoba esters 2-4 weight portion, dicaprylyl carbonate 1-3 weight portion, behenyl alcohol 0.5-1.5 weight portion, cetearyl alcohol 0.5-1.5 weight portion, glyceryl stearate SE0.5-1.5 weight portion, Palmic acid 0.5-0.7 weight portion, hydroxyethyl-cellulose 0.4-0.6 weight portion, stearic acid 0.3-0.5 weight portion, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid 0.3-0.5 weight portion, Tridocosanoin 0.3-0.5 weight portion, 1,3 butylene glycol 0.2-0.4 weight portion, decyl glucoside 0.2-0.3 weight portion, carbomer 0.1-0.3 weight portion, xanthan gum 0.1-0.3 weight portion, phenoxyethanol 0.05-0.15 weight portion, Sensiva SC50 0.05-0.15 weight portion, two (lauramide glutamine) L-Lysine sodium salt 0.08-0.1 weight portion, 1,2-hexanediol 0.07-0.08 weight portion, sodium hydroxide 0.06-0.08 weight portion, tocopherol 0.06-0.07 weight portion, hyaluronate sodium 0.04-0.06 weight portion, sodium lactate 0.01 weight portion, caprylyl glycol 0.025 weight portion, polysorbate-200.005 weight portion, resveratrol 0.005 weight portion, spermol 0.004 weight portion, macadimia nut seed oil 0.0015 weight portion, hydrolysis Lac regis apis albumen 0.001-0.0015 weight portion, octyl dodecanol lauroyl glutamate ester 0.001 weight portion, myristyl alcohol 0.001 weight portion, Palmitoyl Tetrapeptide-70.00005 weight portion, phytosphingosine 0.000025 weight portion, Cer AP II0.000025 weight portion, ceramide 3 0.000025 weight portion, cholesterol 0.000025 weight portion, denatonium benzoate 0.00002 weight portion, Cer EOS 0.0000005 weight portion, retinyl palmitate 0.4-0.6 weight portion, palmitoyl oligopeptide 0.0001 weight portion, Radix Astragali root extract 0.1-0.3 weight portion, Rhizoma Atractylodis Macrocephalae root extract 0.1-0.3 weight portion, Bupleurum krylovianum root extract 0.1-0.3 weight portion.
9. a kind of eye cream according to claim 8, is characterized in that the preparation method of eye cream is:
(1) water intaking, glycerol, 1,3-PD, two (lauramide glutamine) L-Lysine sodium salt, 1,3 butylene glycol, hydroxyethyl-cellulose, xanthan gum, sodium hydroxide, add aqueous phase pot, after being heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(2) Butyrospermum parkii fruit fat, squalane, Jojoba esters, tocopherol, polydimethylsiloxane, dicaprylyl carbonate, glyceryl stearate, cetearyl alcohol, behenyl alcohol, stearic acid, Palmic acid, Tridocosanoin is got, add oil phase pot, be heated to 70-75 DEG C, stir, in suction vacuum emulsifying machine;
(3) start is uniformly mixed, homogenizing 8 minutes, add carbomer, vinyldimethicone/polymethyl siloxane silsesquioxane cross linked polymer, water, decyl glucoside, retinyl palmitate, tocopherol, hydroxypropyl-trimethyl ammonium chloride hyaluronic acid, hyaluronate sodium, start cooling;
(4) 40 DEG C are cooled to, add glycerol, water, 1, 3-butanediol, carbomer, polysorbate-20, palmitoyl oligopeptide, sodium lactate, Palmitoyl Tetrapeptide-7, Radix Astragali root extract, Rhizoma Atractylodis Macrocephalae root extract, Bupleurum krylovianum root extract, 1, 2-hexanediol, caprylyl glycol, phenoxyethanol, Sensiva SC50, tocopherol, hydrolysis Lac regis apis albumen, 1, ammediol, ceramide 3, Cer AP II, Cer EOS, phytosphingosine, cholesterol, myristyl alcohol, spermol, octyl dodecanol lauroyl glutamate ester, two (lauramide glutamine) L-Lysine sodium salt, squalane, macadimia nut seed oil, resveratrol, denatonium benzoate, continue to stir, be cooled to room temperature, fill, to obtain final product.
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Address after: 511434 No. 13, No. 1, Liu Wei street, Hualong Town, Panyu District, Guangzhou, Guangdong. Patentee after: Hua An Tang biotech Group Co., Ltd. Address before: 511434 No. 13, No. 1, Liu Wei street, Hualong Town, Panyu District, Guangzhou, Guangdong. Patentee before: City flower An Tang bio tech ltd, Guangzhou |