CN106109269B - The cosmetics and skincare product of deer oil and antler polypeptide compatibility, preparation method and application - Google Patents
The cosmetics and skincare product of deer oil and antler polypeptide compatibility, preparation method and application Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
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Abstract
Cosmetics and skincare product, the preparation method and application of a kind of deer oil and antler polypeptide compatibility are disclosed, wherein the raw material composition of cosmetics and skincare product is as follows: by percentage to the quality, purified water 51.2%-35%；Deer oil 7%-18%；Antler polypeptide stoste 3.8%-15%；Stabilizer 7%-15%；Glycerol 5%-10%；Propylene glycol 5%-8%；Shea butter 3%-5%；Saualane 3%-5%；Isopropyl palmitate 1.5%-5%；Dimethicone 1%-5%；Azone 1%-2%；Lanolin 0.5%-1.5%；Methyl hydroxybenzoate 0.2%-1%；Vitamin E 0.2%-1%；Allantoin 0.2%-1%；Outstanding horse B0.2%-1%；Essence 0.1%-1%；Wherein, antler polypeptide stoste is the purification of aqueous solutions containing antler polypeptide, and the content of epithelical cell growth factor contained in antler polypeptide stoste is 4.0mg/L.Cosmetics and skincare product according to the present invention, stability is good, percutaneous absorbability is high, can be quickly skin extra-nutrition and moisture, promote the fairness and brightness of skin, can be widely used in beauty, health care and/or skin care.
Description
Technical field
The present invention relates to the cosmetics and skincare product of a kind of cosmetic technical field more particularly to deer oil and antler polypeptide compatibility and
Preparation method and application.
Background technique
Background of related of the invention is illustrated below, but these explanations might not constitute it is of the invention existing
Technology.
Antler polypeptide includes epithelical cell growth factor abundant (Epidermal Growth Factor, EGF) and pancreas
Island element like growth factor, nerve growth factor, transforming growth factor etc..Have it is demonstrated experimentally that these growth factors can speed up table
The division and growth of chrotoplast play an important role to the regeneration and reparation of skin.But the half of these Porcine HGFs
Declining, the phase is short, stability is poor；A variety of growth factors such as EGF are unstable to hot optrode, degradable and easy there are room temperature stability inferior is poor
The disadvantages of inactivation.In addition, it is also its commercialization problem to be solved that Porcine HGF percutaneous absorbability is not high.
Therefore, the prior art that there is an urgent need to develop stability is good, percutaneous absorbability is high cosmetics and skincare product and its preparation side
Method.
Summary of the invention
In order to solve the problems, such as that antler polypeptide exists in the prior art, the present invention provides deer oil and antler polypeptide compatibility
Cosmetics and skincare product and preparation method thereof.
The cosmetics and skincare product of a kind of deer oil and antler polypeptide compatibility, the beauty shield are provided according to an aspect of the present invention
The raw material composition of skin product is as follows:
By percentage to the quality, purified water 51.2%-35%；Deer oil 7%-18%；Antler polypeptide stoste 3.8%-15%；
Stabilizer 7%-15%；Glycerol 5%-10%；Propylene glycol 5%-8%；Shea butter 3%-5%；Saualane 3%-5%；Palm
Isopropyl propionate 1.5%-5%；Dimethicone 1%-5%；Azone 1%-2%；Lanolin 0.5%-1.5%；Methyl hydroxybenzoate
0.2%-1%；Vitamin E 0.2%-1%；Allantoin 0.2%-1%；Outstanding horse B 0.2%-1%；Essence 0.1%-1%；
Wherein, antler polypeptide stoste is the purification of aqueous solutions containing antler polypeptide, table contained in antler polypeptide stoste
The content of skin cell growth factor is 4.0mg/L.
The preparation method of the cosmetics and skincare product is also provided according to another aspect of the present invention, is included the following steps:
(1) after purified water, glycerol, propylene glycol and methyl hydroxybenzoate being mixed and heated to 90 DEG C, heat preservation 30 minutes, urine is added
Bursin obtains water phase material after dissolution；
(2) by deer oil, stabilizer, lanolin, shea butter, saualane, isopropyl palmitate, dimethicone and azone
After being mixed and heated to 90 DEG C, heat preservation 30 minutes, vitamin E is added, obtains oil phase material；
(3) water phase material is mixed with oil phase material, homogeneous, essence and Jie Ma is added when being cooled to 40 DEG C -50 DEG C in stirring
B obtains mixed liquor A；
(4) the antler polypeptide stoste is added into mixed liquor A at 37 DEG C or less, then divides through high pressure low temperature homogeneous 30
Clock；
(6) discharging, ageing, obtain the cosmetics and skincare product when being cooled to 35 DEG C or so.
The third aspect of the present invention also provides the cosmetics and skincare product of first aspect present invention or by second aspect of the present invention
Application of the cosmetics and skincare product obtained in beauty and/or skin care.
Cosmetics and skincare product according to the present invention, stability is good, percutaneous absorbability is high, can be quickly skin extra-nutrition and water
Point, the fairness and brightness of skin are promoted, beauty, health care and/or skin care can be widely used in.
Specific embodiment
Exemplary embodiments of the present invention are described in detail below.Description to illustrative embodiments is only
It for illustration purposes, is definitely not to the present invention and its application or the limitation of usage.
Deer oil is identical as antler polypeptide source, has natural homology, prepares using deer oil and antler polypeptide compatibility
When cosmetics and skincare product, the stability and percutaneous absorbability of various Porcine HGFs in antler polypeptide can be improved.
Growth factor in antler polypeptide exists mostly in the form of protein, even if these growth factor deactivations are still
Exist in the form of protein, therefore should not be using protein content as the index for measuring antler polypeptide stability.Antler polypeptide
It include epidermal growth factor EGF abundant, EGF has the various kinds of cell such as stimulation epidermal cell, endothelial cell, fibroblast
The property of proliferation, can be used to treat or prevent a variety of diseases, such as promote ulcer, burn and scald and operation wound surface healing,
There is certain treatment and prevention effect (referring to Chinese special the illnesss such as atrophic gastritis, oral cavity anabrosis and ischemia injury
Sharp CN1075874A, CN1111505A, CN1290172A, CN1407899A etc.).Add in addition, EGF has been widely used as cosmetics
Add agent and apply, promotes epidermal cell proliferation, improves skin appearance situation.The present invention is with the attenuation of epidermal growth factor EGF
Stability as index study antler polypeptide.
First aspect present invention provides the cosmetics and skincare product of a kind of deer oil and antler polypeptide compatibility, and raw material forms such as
Under:
By percentage to the quality, purified water 51.2%-35%；Deer oil；Antler polypeptide stoste；Stabilizer；Glycerol 5%-
10%, such as 5%, 8%, 10%；Propylene glycol 5%-8%, such as 5%, 5.8%, 6.6%, 7.2%, 8%；Shea butter
3%-5%, such as 3%, 3.5%, 4%, 4.5%, 5%；Saualane 3%-5%, for example, 3%, 3.5%, 4%, 4.5%,
5%；Isopropyl palmitate 1.5%-5%, such as 1.5%, 2%, 3%, 4%, 5%；Dimethicone 1%-5%, such as
1%, 2%, 3%, 4%, 5%；Azone 1%-2%, such as 1%, 1.25%, 1.5%, 1..75%, 2%；Lanolin 0.5%-
1.5%, such as 0.5%, 0.75%, 1%, 1.25%, 1.5%；Methyl hydroxybenzoate 0.2%-1%, for example, 0.2%, 0.4%,
0.6%, 0.8%, 1%；Vitamin E 0.2%-1%, such as 0.2%, 0.4%, 0.6%, 0.8%, 1%；Allantoin
0.2%-1%, such as 0.2%, 0.4%, 0.6%, 0.8%, 1%；Outstanding horse B 0.2%-1%, for example, 0.2%, 0.4%,
0.6%, 0.8%, 1%；Essence 0.1%-1%.
Antler polypeptide is configured to antler polypeptide stoste first, is then prepared again by raw material of antler polypeptide stoste obtained
Cosmetics.Specifically, antler polypeptide freeze-dried powder is dissolved in purified water and prepares antler polypeptide stoste, wherein epidermal growth factor
The content of sub- EGF is 4.0mg/L.In material system of the invention, if the content of antler polypeptide stoste is too low, antler polypeptide
Stability is poor, and epithelical cell growth factor EGF is easy deactivation during long-term preservation, is not easy to extend obtained beauty
The shelf-life of skin care item；If the too high levels of antler polypeptide stoste, in material system, antler polypeptide stoste and the ratio of deer oil be not
Coordinate, so that material system differs larger with the metabolism environment of living body deer itself, is equally unfavorable for extending obtained cosmetics and skincare product
Shelf-life.By percentage to the quality, the content of antler polypeptide stoste is 3.8%-15% to the present invention, for example, 3.8%, 6%,
9%, 12%, 15%.
In the prior art generally using antler polypeptide as raw material, in conjunction with stabilizer, preservative etc., other raw materials prepare cosmetics,
But the material system of these cosmetics differed with the metabolism environment of living body deer itself cause farther out the stability of antler polypeptide compared with
Difference.For the present invention using deer oil and antler polypeptide compatibility, one side deer oil penetration is very strong, can quickly be absorbed by skin, by blood
Liquid is transmitted to subcutaneous tissue, effectively facilitates blood circulation, accelerates metabolism, improves the beauty and health care work that cosmetics and skincare product is made
With；On the other hand, fatty acid rich in deer oil, has excellent bio-compatibility with antler polypeptide, closest to living body
The own metabolism environment of deer is conducive to the stability for improving antler polypeptide, extends the shelf-life that cosmetics and skincare product is made.If deer is oily
Too high levels will increase the cost for preparing cosmetics and skincare product, and obtained cosmetics and skincare product is more greasy, poor user experience；If deer
Oil content is too low, is unfavorable for improving the transdermal absorption factor of various nutritional ingredients in cosmetics and skincare product, reduces beauty and health care effect.This
By percentage to the quality, the content of deer oil is 7%-18%, such as 7%, 9%, 13%, 15%, 18% for invention.
Based on deer oil and antler polypeptide to the effect of skin from the point of view of, the two has similar function similar in other words, meets
The characteristics of mutually making in Chinese pharmacology, mutual reinforcement between, this is objective condition and theoretical foundation proposed by the present invention.The present inventor is by long-term
The study found that the stability of antler polypeptide can be significantly improved using deer oil and antler polypeptide compatibility, antler polypeptide is made to be not easy to drop
Solution inactivation, deer oil and antler polypeptide can mutual reinforcement between mutually make, synergy, the stability and persistent of cosmetics and skincare product obtained
Property is more preferable, much larger than the sum of deer oil and the effect of antler polypeptide.In the material system of cosmetics and skincare product, when deer oil and pilose antler are more
The mass ratio of peptide stoste are as follows: when 1.5-2.5:1, the synergistic effect of the two is optimal.
Make it comprising plurality of raw materials and nutritional ingredient in cosmetics and skincare product in order to improve the stability of various nutritional ingredients
It will not go bad, mildew, oxidation, inactivation, decomposition, split-phase, it is necessary to stabilizer, such as hexadecanol, ten be added in material system
Eight alcohol, eicosanol, docosanol etc..Mass percent of the stabilizer in material system is 7%-15% in the present invention, such as
7%, 9%, 11%, 13%, 15%.If the additive amount of stabilizer is excessive, it is excessively sticky to will lead to cosmetics and skincare product obtained, drop
Ion water content in low cosmetics and skincare product reduces it to the replenishing water and preserving moisture effect of skin；Too low ion water content also shadow
Absorption of the skin to bioactive substance in cosmetics and skincare product is rung, beauty and health care effect is reduced.If the additive amount of stabilizer is too small,
The emulsification toughness of cosmetics and skincare product is too low, is easy to cause cosmetics and skincare product split-phase, reduces the duration of action of cosmetics and skincare product
The wherein stability of bioactive substance, make its oxidation, decompose, inactivate etc..In addition, stabilizer used in cosmetics is general
With fragrance, additive amount has influence to the additive amount of the fragrance of obtained cosmetics and skincare product and essence, obtained in order to make
Cosmetics and skincare product has specific fragrance, it is necessary to control the additive amount of stabilizer.In raw material in material system of the invention
In system, the additive amount of essence is respectively 7%-15%, 0.1%-1%, such as 0.2%, 0.4%, 0.6%, 0.8%, 1%.
Octadecyl alcolol is also octadecanol, refers to the Organic Alcohol containing 18 carbon atoms.Octadecyl alcolol is white, is not dissolved in
Water has fragrance, is frequently used for the emulsion stabilizer of cosmetics, and suitable octadecyl alcolol can reduce adding for essence in material system
Dosage.Docosanol refers to the Organic Alcohol containing 22 carbon atoms, and white is not soluble in water, is frequently used for the viscosity of cosmetics
Stabilizer can adjust viscosity, the skin care, hydrotropy bioactive substance of cosmetics.The present invention of the invention is ground for a long time
Study carefully middle discovery, while using octadecyl alcolol and docosanol as stabilizer to the emulsion stability and persistent of cosmetics and skincare product
The effect of property is best, wherein by percentage to the quality, octadecyl alcolol 2%-5%；Docosanol 5%-10%.
In order to improve the transdermal absorption factor of obtained cosmetics and skincare product, suitable spiny dogfish is added in the present invention in material system
Alkane.Saualane is closest to a kind of lipid of human sebaceous, and affinity is strong, can speed up in material system other active components to
It is permeated in skin, and without greasy feeling.Preferably, by percentage to the quality, the additive amount of saualane is 3%-5%, such as
3%, 3.5%, 4%, 4.5%, 5%.
In a preferred embodiment, the raw material composition of cosmetics and skincare product is as follows:
By percentage to the quality, purified water 48.8%；Deer oil 10%；Antler polypeptide stoste 4.8%；Docosanol 8%；It is sweet
Oil 6%；Propylene glycol 5%；Octadecyl alcolol 4%；Shea butter 4%；Saualane 3.2%；Isopropyl palmitate 1.5%；Dimethyl-silicon
Oil 1%；Azone 1%；Lanolin 1%；Methyl hydroxybenzoate 0.2%；Vitamin E 0.7%；Allantoin 0.2%；Outstanding horse B 0.5%；
Essence 0.1%.
The present invention also provides the preparation methods of above-mentioned cosmetics and skincare product, include the following steps:
(1) after purified water, glycerol, propylene glycol and methyl hydroxybenzoate being mixed and heated to 90 DEG C, heat preservation 30 minutes, urine is added
Bursin obtains water phase material after dissolution；
(2) by deer oil, stabilizer, lanolin, shea butter, saualane, isopropyl palmitate, dimethicone and azone
After being mixed and heated to 90 DEG C, heat preservation 30 minutes, vitamin E is added, obtains oil phase material；
(3) water phase material is mixed with oil phase material, homogeneous, essence and Jie Ma is added when being cooled to 40 DEG C -50 DEG C in stirring
B obtains mixed liquor A；
(4) the antler polypeptide stoste is added into mixed liquor A at 37 DEG C or less, then divides through high pressure low temperature homogeneous 30
Clock；
(6) discharging, ageing, obtain the cosmetics and skincare product when being cooled to 35 DEG C or so.
Cosmetics and skincare product is directly contacted with skin, wherein adulterates more impurity in order to prevent, can be into one after step (1)
Step includes: to carry out taking out material filtering to water phase material, removes the impurity in water phase material.The temperature and pressure of suction filtration can be according to reality
Border situation is determined, and the present invention is not especially limited this.
In material system, the particle of raw material cannot be too big, otherwise influences absorption of the skin on substance is wherein influenced；Particle compared with
The stability of obtained cosmetics and skincare product can also be had an impact greatly, be easy to produce split-phase.In a preferred embodiment of the invention, it walks
Suddenly the homogenizing time in (3) is 15min.Homogenizing time is too short, is easy to cause feed particles larger, is unfavorable for cosmetics and skincare product
The stable and wherein absorption of nutriment；Homogenizing time is too long, is easily destroyed the structure of wherein nutriment, influences beauty shield
The beauty and health care effect of skin product.
In order to remove the solid impurity in material system as far as possible, may further include before step (4): using preceding right
Antler polypeptide stoste carries out hyperfiltration treatment.Due to other amino in the bioactive substance and material system in antler polypeptide
Acid and vitamin are to light and heat-sensitive, therefore hyperfiltration treatment should be maintained at 37 DEG C or less as far as possible.
The third aspect of the present invention also provides the cosmetics and skincare product of first aspect present invention or by second aspect of the present invention
Application of the cosmetics and skincare product obtained in beauty, health care and/or skin care.For in terms of the functional effect, the present invention can be answered
For whitening, moisturizing, crease-resistant, nti-freckle, sun-proof etc., in terms of the product form for, the present invention can be used for preparing various face creams,
Facial mask, lotion, lotion, skin lotion etc..
Below with reference to embodiment, the invention will be further described.These embodiments are only with regard to preferred implementation side of the invention
Formula is illustrated, and protection scope of the present invention is not read as pertaining only to these embodiments.
Embodiment 1-16
Raw material composition: by percentage to the quality, glycerol 6%；Propylene glycol 5%；Shea butter 4%；Saualane 3.2%；Palm fibre
Palmitic acid isopropyl propionate 1.5%；Dimethicone 1%；Azone 1%；Lanolin 1%；Methyl hydroxybenzoate 0.2%；Vitamin E 0.7%；
Allantoin 0.2%；Outstanding horse B 0.5%；Essence 0.1%；Purified water: surplus；Other raw materials are according to raw material described in table 1 and its use
Amount.Preparation step is as follows:
(1) after purified water, glycerol, propylene glycol and methyl hydroxybenzoate being mixed and heated to 90 DEG C, heat preservation 30 minutes, urine is added
Bursin takes out material filtering, obtains water phase material after dissolution；
(2) by deer oil, stabilizer, lanolin, shea butter, saualane, isopropyl palmitate, dimethicone and azone
After being mixed and heated to 90 DEG C, heat preservation 30 minutes, vitamin E is added, obtains oil phase material；
(3) water phase material is mixed with oil phase material, homogeneous 15min, be added when stirring is cooled to 40 DEG C -50 DEG C essence and
Outstanding horse B, obtains mixed liquor A；
(4) hyperfiltration treatment is carried out to mixed liquor A, antler polypeptide stoste is then added thereto at 37 DEG C or less, through high pressure
Low temperature homogeneous 30 minutes；
(6) discharging, ageing, obtain the cosmetics and skincare product, by cosmetics and skincare product of the invention when being cooled to 35 DEG C or so
It is prepared into facial mask.
The measurement of antler polypeptide stability in facial mask is made in different embodiments:
It uses mass fraction for 5% NaCl solution demulsification extracting antler polypeptide, then utilizes MTT Determination Staining facial mask
The content c of mesocuticle Porcine HGF EGF0And after 12 months epithelical cell growth factor EGF content c12, thin with epidermis
For the attenuation of intracellular growth factor EGF as the index for measuring antler polypeptide stability, attenuation is smaller, shows that antler polypeptide is more steady
It is fixed.Wherein, the attenuation that epithelical cell growth factor EGF is calculated according to following formula, is as a result listed in the table below in 1:
EGF attenuation=(c0-c12)/c0× 100%.
1 embodiment of table and experimental result
Note: in upper table, the storage temperature of cosmetics and skincare product is 4 DEG C.
It can be seen that using deer oil that can significantly reduce epidermis with antler polypeptide compatibility thin from the experimental result of Examples 1 and 2
The attenuation of intracellular growth factor EGF, extends the shelf-life of facial mask.The present invention also feels facial mask made from above-described embodiment
Official's test, from the point of view of the experience feedback result of volunteer, compared with or antler polypeptide oily using deer merely, using deer oil and pilose antler
The sensory evaluation of the facial mask of polypeptide compatibility preparation is preferable, with rear skin wet is tight, high resilience, non-greasy.
It can be seen that the adding too much of deer oil from the experimental result of embodiment 2-5 or too low can improve epidermal cell
The attenuation of growth factor EGF influences the shelf-life of facial mask.It can be seen that antler polypeptide from the experimental result of embodiment 6-10
Additive amount be also not easy too high or too low, otherwise can also improve the attenuation of epithelical cell growth factor EGF.
It can be seen that compared with merely using octadecyl alcolol or docosanol as stabilizer, use from embodiment 11-16
Octadecyl alcolol and docosanol compatibility can significantly reduce the attenuation of epithelical cell growth factor EGF.In addition, octadecyl alcolol and 22
The additive amount of alcohol also has certain influence, the too low or excessively high shelf-life for being unfavorable for extending cosmetics and skincare product to EGF decrement.
The measurement of stability of the antler polypeptide under condition of different temperatures in facial mask:
Using facial mask made from embodiment 1 as a control group, facial mask made from embodiment 3 as experimental group, measure it respectively
In epithelical cell growth factor EGF saved 6 months and 12 months under three kinds of condition of different temperatures after attenuation, as a result such as
Shown in the following table 2.Three kinds of temperature conditions are respectively as follows: 4 DEG C；25℃；4 DEG C, 25 DEG C of cycle alternations, wherein 4 DEG C of preservation 1h, 25 DEG C of preservations
23h。
Table 2 studies stability of the antler polypeptide under condition of different temperatures
From table 2 it can be seen that EGF attenuation of control group under the conditions of three kinds of temperature is 80% left after saving 6 months
It is right；And the EGF attenuation of experimental group is far below control group less than 15%, it is seen that antler polypeptide in facial mask produced by the present invention
Stability is more preferable, acts on more longlasting.After control group saves 12 months under the conditions of three kinds of temperature, EGF attenuation is close
100%, antler polypeptide substantially completely inactivates；And for EGF attenuation less than 30%, the stability of antler polypeptide is obvious in experimental group
Higher than control group, illustrate the stability that antler polypeptide can be significantly improved using deer oil and antler polypeptide compatibility.In the present embodiment
Under the conditions of three kinds of temperature, EGF attenuation is minimum when 4 DEG C of preservations, and the stability of antler polypeptide is best.
Compared with prior art, the present invention prepares cosmetics and skincare product using deer oil and antler polypeptide compatibility, antler polypeptide with
Deer oil source is identical, has natural homology, bio-compatibility good, and the two has close place again on composition and function, therefore
This formula compatibility mutual reinforcement between mutually makes, synergistic, scientific and reasonable, and effect ratio is used alone more significant, improves antler polypeptide
The persistence of stability and product effect.In addition, antler polypeptide included various growth factors, deer oil in various amino acid
The beneficial nutrient of ingredient and vitamin can keep its bioactivity under natural physiological environment as far as possible, deeper in iuntercellular
It broadly spreads apart, quickly supplements the nutrients for skin；Those moisture that can not be evaporated of skin surface can then be deposited in epidermis, table
The moisture of cortex is full, skin seem will smoother it is tight, microgroove can also become light, while fairness, light
Brightness is obviously improved.
Although referring to illustrative embodiments, invention has been described, but it is to be understood that the present invention does not limit to
The specific embodiment that Yu Wenzhong is described in detail and shows, without departing from claims limited range, this
Field technical staff can make various changes to the illustrative embodiments.
Claims (8)
1. a kind of cosmetics and skincare product of deer oil and antler polypeptide compatibility, which is characterized in that the raw material of the cosmetics and skincare product forms
It is as follows:
By percentage to the quality, purified water 51.2%-35%；Deer oil 7%-18%；Antler polypeptide stoste 3.8%-15%；Stablize
Agent 7%-15%；Glycerol 5%-10%；Propylene glycol 5%-8%；Shea butter 3%-5%；Saualane 3%-5%；Palmitinic acid is different
Propyl ester 1.5%-5%；Dimethicone 1%-5%；Azone 1%-2%；Lanolin 0.5%-1.5%；Methyl hydroxybenzoate 0.2%-
1%；Vitamin E 0.2%-1%；Allantoin 0.2%-1%；Outstanding horse B 0.2%-1%；Essence 0.1%-1%；
Wherein, antler polypeptide stoste is the purification of aqueous solutions containing antler polypeptide, and epidermis contained in antler polypeptide stoste is thin
The content of the intracellular growth factor is 4.0mg/L；
The stabilizer includes octadecyl alcolol and docosanol, wherein by percentage to the quality, octadecyl alcolol 2%-5%；Docosanol
5%-10%.
2. cosmetics and skincare product as described in claim 1, wherein the mass ratio of deer oil and antler polypeptide stoste is 1.5-2.5:1.
3. cosmetics and skincare product as described in claim 1, wherein the raw material composition of the cosmetics and skincare product is as follows:
By percentage to the quality, purified water 48.8%；Deer oil 10%；Antler polypeptide stoste 4.8%；Docosanol 8%；Glycerol
6%；Propylene glycol 5%；Octadecyl alcolol 4%；Shea butter 4%；Saualane 3.2%；Isopropyl palmitate 1.5%；Dimethicone
1%；Azone 1%；Lanolin 1%；Methyl hydroxybenzoate 0.2%；Vitamin E 0.7%；Allantoin 0.2%；Outstanding horse B 0.5%；It is fragrant
Essence 0.1%.
4. the preparation method of cosmetics and skincare product a method according to any one of claims 1-3, it is characterised in that include the following steps:
(1) after purified water, glycerol, propylene glycol and methyl hydroxybenzoate being mixed and heated to 90 DEG C, heat preservation 30 minutes, allantois is added
Element obtains water phase material after dissolution；
(2) deer oil, stabilizer, lanolin, shea butter, saualane, isopropyl palmitate, dimethicone and azone are mixed
And 90 DEG C are heated to, after heat preservation 30 minutes, vitamin E is added, obtains oil phase material；
(3) water phase material is mixed with oil phase material, homogeneous, essence and Jie Ma B is added when being cooled to 40 DEG C -50 DEG C in stirring, obtains
To mixed liquor A；
(4) the antler polypeptide stoste is added into mixed liquor A at 37 DEG C or less, then through high pressure low temperature homogeneous 30 minutes；
(6) discharging, ageing, obtain the cosmetics and skincare product when being cooled to 35 DEG C.
5. preparation method as claimed in claim 4, step (1) further comprise later: water phase material is carried out to take out material filtering,
Remove the solid impurity in water phase material.
6. preparation method as claimed in claim 5, the homogenizing time in step (3) is 15min.
7. preparation method as claimed in claim 5, step (4) further comprise before: at 37 DEG C or less to institute before using
It states antler polypeptide stoste and carries out hyperfiltration treatment.
8. made from cosmetics and skincare product a method according to any one of claims 1-3 or any preparation method of claim 4-7
Application of the cosmetics and skincare product in the beauty and/or skin care of non-therapeutic.
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| CN111358715A (en) * | 2019-04-18 | 2020-07-03 | 吉林省东鳌鹿业科技开发有限公司 | Deer collagen polypeptide repair eye cream and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266280A (en) * | 2011-07-25 | 2011-12-07 | 吉林农业大学 | Application of refined deer oil to preparation of moisture preserving cosmetics |
| CN103110534A (en) * | 2013-01-29 | 2013-05-22 | 海南巨鹿堂保健美容品有限公司 | Combined essence of composite velvet antler polypeptide lyophilized powder and nano-scale buffering microemulsion for skin beauty and health care and preparation method of combined essence |
| CN105250173A (en) * | 2015-10-16 | 2016-01-20 | 刘爱红 | Skin-whitening and skin-tendering skin care product |
| CN105287320A (en) * | 2015-12-08 | 2016-02-03 | 广州市花安堂生物科技有限公司 | Mild lifting and repairing eye cream and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266280A (en) * | 2011-07-25 | 2011-12-07 | 吉林农业大学 | Application of refined deer oil to preparation of moisture preserving cosmetics |
| CN103110534A (en) * | 2013-01-29 | 2013-05-22 | 海南巨鹿堂保健美容品有限公司 | Combined essence of composite velvet antler polypeptide lyophilized powder and nano-scale buffering microemulsion for skin beauty and health care and preparation method of combined essence |
| CN105250173A (en) * | 2015-10-16 | 2016-01-20 | 刘爱红 | Skin-whitening and skin-tendering skin care product |
| CN105287320A (en) * | 2015-12-08 | 2016-02-03 | 广州市花安堂生物科技有限公司 | Mild lifting and repairing eye cream and preparation method thereof |
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