CN109620795A - A kind of whitening and spot eliminating cream and preparation method thereof of releiving of the ferment powder containing whitening - Google Patents

A kind of whitening and spot eliminating cream and preparation method thereof of releiving of the ferment powder containing whitening Download PDF

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Publication number
CN109620795A
CN109620795A CN201910045460.9A CN201910045460A CN109620795A CN 109620795 A CN109620795 A CN 109620795A CN 201910045460 A CN201910045460 A CN 201910045460A CN 109620795 A CN109620795 A CN 109620795A
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Prior art keywords
whitening
skin
ingredient
ferment powder
phase
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Inventor
肖夏旭
傅建斌
易黎明
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Guangzhou Li Li Cosmetics Biotechnology Co Ltd
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Guangzhou Li Li Cosmetics Biotechnology Co Ltd
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Priority to CN201910045460.9A priority Critical patent/CN109620795A/en
Publication of CN109620795A publication Critical patent/CN109620795A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

Abstract

The present invention relates to cosmetic technical fields, whitening and spot eliminating cream and preparation method thereof of releiving of specifically a kind of ferment powder containing whitening, is made by the component of following quality proportionings: dipropylene glycol, propylene glycol, glycerol, SOD whitening ferment powder, niacinamide, arbutin, dipotassium glycyrrhizinate, nonapeptide -1 etc.;The two of task of the present invention are to provide a kind of preparation method of the whitening and spot eliminating cream of releiving of ferment powder containing whitening.

Description

A kind of whitening and spot eliminating cream and preparation method thereof of releiving of the ferment powder containing whitening
Technical field
The present invention relates to cosmetic technical field, releive whitening and spot eliminating cream and its system of specifically a kind of ferment powder containing whitening Preparation Method.
Background technique
Dermal melanin calmness is a kind of common multiple cutaneous disease.Including chloasma, senile plaque, freckle etc., draw The reason of playing skin melanin pigmentation predominantly human endocrine is lacked of proper care, and metabolic function weakens etc., secondly solarization, ultraviolet light Radiation, sleep insufficiency can aggravate pigmentation.Some whitening and freckle-removing products on existing market make skin in a very short period of time Bleach, once deactivating, skin becomes more black immediately, and pigment rebound, wrinkle is deepened.The reason is that despeckle cosmetics be often added to it is super The substance toxic to human skin, nervous system such as target lead, mercury, the heavy metal ion such as lead, mercury can act on melanin production Tyrosinase in the process, causes it to lose its activity, to prevent the formation of color spot, allows whiteness of skin.But this effect is short Temporary, the consequence ultimately caused is tyrosinase or is unlimitedly catalyzed the generation of melanin, makes skin darkening, pigment is anti- Bullet, or even there is heavy metal poisoning spot.
Summary of the invention
In order to overcome the above the deficiencies in the prior art, one of task of the invention is to provide a kind of relaxing for ferment powder containing whitening Slow whitening and spot eliminating cream, a kind of whitening and spot eliminating cream product of releiving of the ferment powder containing whitening is frivolous docile, and quality is fine and smooth, is easy to It smears, not card powder, easy makeup, rear makeup is persistently good, while makeups, also there is the characteristics of face cream;The two of task of the present invention It is to provide a kind of preparation method of the whitening and spot eliminating cream of releiving of ferment powder containing whitening.
One of task of the present invention is achieved through the following technical solutions:
A kind of whitening and spot eliminating cream of releiving of the ferment powder containing whitening, is made by the component of following quality proportionings:
Dipropylene glycol: 2-3%;
Propylene glycol: 2-3%;
Glycerol: 0.5-1%;
SOD whitening ferment powder: 2-2.5%;
Niacinamide: 2-2.5%;
Arbutin: 2-2.5%;
Dipotassium glycyrrhizinate: 0.4-0.5%;
Nonapeptide -1:0.2-0.5%;
Acetyl group hexapeptide -1:0.2-0.5%;
PEG-12 dimethyl silicone polymer: 1-1.5%;
GC-04:0.5-1%;
FCP-AK:0.5-1%;
PLANT 21:3-5%;
GL sweet dew ester: 2-3%;
E-Pearl PMF:2-3%;
AVH emulsifier: 1.5-2%;
Cetanol ethylhexoate: 3-4%;
Jojoba (SIMMONDSIA CHINENSIS) seed oil: 3-4%;
Saualane: 1.5-2%;
Queensland nut (MACADAMIA TERNIFOLIA) seed oil: 2-3%;
Multiflora rose (ROSA MULTIFLORA) fruit oil: 1-1.5%;
Essence: 0.05-0.1%;
Water: 52.9-67.65%;
The ingredient of the SOD whitening ferment powder are as follows: Bacillus acidi lactici/pomegranate (PUNICA GRANATUM) fruit tunning mentions Take object, the ingredient of the GC-04 are as follows: decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone;The component of the FCP-AK are as follows: Hydrolytic collagen/dipeptides -1;The ingredient of the PLANT 21 are as follows: butanediol, golden yellow chamomile (CHRYSANTHELLUM INDICUM) extract, peppermint (MENTHA ARVENSIS) leaf extract, aloe barbadensis Miller (ALOE BARBADENSIS) extract Object, kuh-seng (SOPHORA ANGUSTIFOLIA) root extract, Pelargonium roseum (PELARGONIUM GRAVEOLENS) are extracted Object;The ingredient of the GL sweet dew ester are as follows: trimethylpentanediol/adipic acid/glycerin crosspolymers;The E-Pearl PMF's Ingredient are as follows: water/poly methyl silsesquioxane/dimethyl silicone polymer/isohexadecane/16 octadecyl methyl siloxanes/ PEG-40 stearate ester/- 2/ stereth -21 of stereth;The ingredient of the AVH emulsifier are as follows: Sodium Polyacrylate/ Ethylhexyl stearate/trideceth -6.
In the present invention dipropylene glycol, that is, dipropylene glycol can also in a variety of different cosmetics applications as coupling agent and Moisturizer.This raw material has good moisture, and oil and hydrocarbon are total to molten ability, and smell is slight, pierces to skin Swash property very little.Isomer is evenly distributed unanimously, and quality is splendid.
Propylene glycol can be used as wetting agent with glycerol or sorbierite cooperation in cosmetics, toothpaste and perfumed soap in the present invention.? It is used as damping, even hair agent in hair dye, also serves as antifreezing agent, be also used to glassine paper, plasticizer and pharmaceuticals industry.
Glycerol is colourless sweet clear and bright thick liquid in the present invention.It is odorless.There is warm sweet taste.It can be used as solvent, lubricant, medicine Agent and sweetener.
SOD whitening ferment powder is also known as the extraction of Bacillus acidi lactici/pomegranate (PUNICA GRANATUM) fruit tunning in the present invention Object, tunning and extract are all mainly lactic acid.Additional some protease, vitamin series, organic matter (alcohol, phenol, insatiable hunger And fatty acid) etc., depending on fermentation material and extraction process, component content is more, is the non-defective unit of natural whiting ingredient.Except nutrition is rich It is rich outer.Main function is embodied in the following: 1. lactic acid play the role of good cutin-softening, there is fabulous smooth tender skin Effect, effect are well suited for that scalp is anti-dandruff and Oily it may be said that get instant result.2. good moistening effect, a small amount of addition is just There is the effect of good moisturizing skin.
Vitamin B3 is also known as niacinamide, as a kind of medical components have very high safety and clinic skin The basic vitamins replenishers of one of section's treatment, are ready for use on treatment photosensitive dermatitis, acne etc. relatively broadly.In recent years Come research have shown that, it inhibit melanin pigmentation, in terms of also have good curative effect;Based on this feature, niacinamide Further extension has been obtained in the application of cosmetic field, other than traditional whitening effect, also be used to reduce raw At the melanin of, precipitating, its transfer to cells of superficial layer is obstructed, accelerate that cell metabolism, to accelerate melanin horn cell de- It falls.Niacinamide is able to maintain that skin water content, promotes skin corium microcirculation.Niacinamide can also greatly reduce or to eliminate skin old Change phenomenon, for example wrinkle, peeling, pore are coarse etc., reduce injury of the free radical to skin, play pre- anti-aging, repair skin The effect obscure with face is reduced.Niacinamide can promote hair follicle blood circulation, and then promote natural on-off cycles of hair growth, prevent hair loss.
Arbutin is also known as Arbutin, can significantly inhibit accumulation of the tyrosinase in cortex, has Bleachability effect to skin, It can be used for preventing skin splash and freckle, effect is better than kojic acid and ascorbic acid.Restraint ratio B of the α type to tyrosinase activity About 10 times by force of type.There is research to think that the mechanism of action of arbutin is identical as quinhydrones, because of arbutin energy in the presence of appropriate acid, enzyme The free quinhydrones of release, therefore arbutin is not sufficiently stable in cream kind cosmetics as quinhydrones.Although arbutin has whitening Effect, but dosage improper (content is greater than 7%) may promote the generation of melanin instead.It can inhibit egg when arbutin experiment in vitro The degradation of white matter such as insulin etc. can mitigate and reduce the stimulation of surfactant or hair dye to skin and hair, equally It can promote dermal cell growth and help healing of wound.The Skin Cell in vitro culture experiment of people shows the micro presence of arbutin When (10-3mmol/L), vitro growth rates are significantly improved, and have nursing function to skin.
Dipotassium glycyrrhizinate is used as skin conditioning agent, predominantly the glycyrrhizin (glycyrrhizic acid) of Radix Glycyrrhizae root and stem Ingredient is suitble to anaphylaxis skin, anti-irritant and oil-control, moves back red and swollen antiphlogistic healing effect.Can effectively prevent skin it is stimulated when it is sensitive Inflammation phenomenon.Inflammation caused by counterglow has anti-inflammatory sedation, is commonly used for antiallergy and repairs in cosmetics.
Nonapeptide -1 is by arginine, lysine, methionine, phenylalanine, proline, tryptophan and valine in the present invention Composition, primary efficacy is bright color.It to Mcl-R have high compatibility, by with α-MSH competitive binding MCl-R receptor, The generation for further preventing tyrosinase, causes melanin production to receive inhibition, to reduce melanin pigmentation.
Acetyl group hexapeptide -1 is α-MSH bionic peptide in the present invention, is the agonist of α-MSH a kind of, by adjust by The synthesis of body MCl-R activity promotion melanin.It can be used as natural sun-screening agent, can enhance skin to ultraviolet radiation resisting Ability avoids skin from symptom of erythema occur, promotes light protection and anti-inflammatory effect, while can also promote adding for hair color Deep and reverse grey hair.
ES-5373 component is PEG-12 dimethyl silicone polymer in the present invention, is a kind of different polymerization degree chain structure Polysiloxane is that outstanding assistant for emulsifying agent and lubrication skin do agent.
GC-04 contains natural fatty acid glyceride, decoyl hydroximic acid and parahydroxyacet-ophenone in the present invention, wherein glycerol Aliphatic ester is a kind of active skull cap components being present in human breast milk, can enhance newborn infant diseases resistance and immunity, The mild polarity of skin is good, inhibits bacterium to agree yeast increment activity, also there is moisturizing, emulsification, moisturizing, wetting and Sage Extract etc. Effect;Parahydroxyacet-ophenone be present in compositae plant artemisia scoparia (Artemisia scoparia Waldst.et kit.) stem, Leaf and the anti-wormwood artemisia of mattress (A.capillaris Thunb.), Luo Mo section plant kerr tylophora root (Tylophora Kerrii It is natural antioxidant in the plants such as root Craib);Decoyl hydroximic acid is a no added preservative, its energy bactericidal, Solubilized hydrotropy.
FCP-AK component is hydrolytic collagen and dipeptides -1 in the present invention, and collagen is a kind of high molecular functional albumen Matter, it is the chief component of skin, accounts for the specific gravity of dermal layer of the skin 80%.
Deionized water is solvent in the present invention.
PLANT 21 is by water, butanediol, glycerol, golden yellow chamomile (CHRYSANTHELLUM INDICUM) in the present invention Extract, peppermint (MENTHA ARVENSIS) leaf extract, aloe barbadensis Miller (ALOE BARBADENSIS) extract, kuh-seng (SOPHORA ANGUSTIFOLIA) root extract, Pelargonium roseum (PELARGONIUM GRAVEOLENS) extract, dent It releives anti-sensitizer made of amaranth (PORTULACAOLERACEA) extract, sodium benzoate, potassium sorbate compounding.Golden yellow chamomile (Shu Min, maintenance sensitivity skin reduce rubescent antipruritic, promotion wound healing and skin regeneration), dried peppermint leaf (inhibits and paralysis is felt Nerve endings, can be used as counter-stimulus has antiallergy and itching-relieving action to pruitus), (antibacterial is sun-proof, nourishes rough skin for aloe Accelerate skin metabolism, enhancing skin elasticity), radix sophorae (rich in alkaloids antiallergies such as matrine and oxymatrines, resists It is scorching, to improve immunity, desinsection antipruritic), (fish pelargonium is the tonic of nervous system to fish pelargonium, can put down and comfort anxiety, dejected, moreover it is possible to mention Vibration mood.Mental recovery is allowed to balance, and since it can also influence adrenal cortex, it can relieve pressure.)
GL sweet dew ester ingredient is base pentanediol/adipic acid/glycerin crosspolymers in the present invention, is a moisturizer, has Moisturizing and increase lubrication sense effect.
E-Pearl PMF is by water, polyphenylsilsesquioxane, dimethyl silicone polymer, isohexadecane, whale in the present invention The lotion that wax stearyl polymethyl siloxane, PEG-40 stearate, stereth -2, stereth -21 form, is one Non-ionic silicone lotion of the kind containing poly methyl silsesquioxane, poly methyl silsesquioxane, dimethyl silicone polymer, can Outstanding pliability, moisture retention, desalination wrinkle and promotion whiteness are provided.
The cream that AVH emulsifier is made of Sodium Polyacrylate, ethylhexyl stearate, trideceth -6 in the present invention Agent.There is excellent emulsification thickening power to water oil.
UN-258 seabird oil, that is, cetanol ethylhexoate in the present invention.Cetanol ethylhexoate is commonly called as seabird feather Oil, the especially excellent emollients of waterproof performance have gas permeability and spreadability good, not sticky, have thickening efficiency, can moisten soft The advantages of soft skin.It can be applied to lipstick and make colorant dispersant and basic finish, glossy dose of lipstick, brilliantine agent, cream emulsion Softening agent.
Saualane is synthesized in the present invention, saualane is that rare chemical stability is high, and the splendid animal fat of use feeling is right Skin has preferable compatibility, will not cause allergy and stimulation, and other active components in formula can be accelerated to permeate into skin; With lower polarity and medium spreadability, and pure, colourless, free from extraneous odour
Oil of Queensland nut (MACADAMIA TERNIFOLIA) the seed oil containing a large amount in the present invention, especially to be rich in insatiable hunger With the characteristics of fatty acid, based on oleic acid and palmitinic acid, it is the preferable edible nut of quality in the world, is known as " dry fruit queen " The laudatory title of " king of world's nut ", macadimia nut oil can prevent heart disease, high natural of this monounsaturated fatty acids content Vegetable oil, the lipid-metabolism for being adjustable and controlling blood glucose level, improve diabetic are the good fat supplements of diabetic Source.Can also effective preserving moisture and protecting skin, be good sun-proof, skin-protection product.
There is rose hip oil in the present invention strengthens tissue effect, generates the effect of active tissue, readily permeable skin corium is protected It is wet, the effect of promoting skin smooth whitening.To cytothesis, maintenance and healing play the role of it is splendid.It can make skin-color plain Change, reappears homogeneous hue, keep skin smooth.It is able to maintain skin cleaning, and soft, soft, wet, deflation is solid, rich in bullet The effect of property, Feng Li.Effect is more especially shown in general coarse skin.
Essence in the present invention is tarted up for cosmetics.
The two of task of the present invention realize by following technical solution:
A kind of a kind of above-mentioned preparation method of the whitening and spot eliminating cream of releiving of the ferment powder containing whitening, comprising the following steps:
S1. dipropylene glycol, propylene glycol, glycerol, the SOD whitening ferment powder, niacinamide, bear of molten A phase are weighed by quality proportioning Fruit glycosides, dipotassium glycyrrhizinate, nonapeptide -1, acetyl group hexapeptide -1, PEG-12 dimethyl silicone polymer, GC-04, FCP-AK, water, PLANT 21, GL sweet dew ester, E-Pearl PMF, AVH emulsifier sequentially add water phase pot and stir evenly.
S2. cetanol ethylhexoate, the Jojoba (SIMMONDSIA CHINENSIS) of molten B phase are weighed by quality proportioning Seed oil, saualane, Queensland nut (MACADAMIA TERNIFOLIA) seed oil, multiflora rose (ROSA MULTIFLORA) fruit oil add Enter in oily phase pot, is mixed evenly.
S3. material in A phase is pumped into emulsion pot and is stirred
During S4.A phase materials persistently stir, B phase materials are pumped into A phase emulsion pot and obtain Material C, stirred 3 minutes, high speed It homogeneous 5 minutes, persistently stirs evenly.
S5. Material C is added in essence by quality proportioning, can discharged after mixing evenly.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that saying that the specific embodiment of description is used only for explaining the present invention herein, it is not used to Limit the present invention.
A kind of whitening and spot eliminating cream of releiving of the ferment powder containing whitening, is made by the component of following quality proportionings:
Dipropylene glycol: 2-3%;
Propylene glycol: 2-3%;
Glycerol: 0.5-1%;
SOD whitening ferment powder: 2-2.5%;
Niacinamide: 2-2.5%;
Arbutin: 2-2.5%;
Dipotassium glycyrrhizinate: 0.4-0.5%;
Nonapeptide -1:0.2-0.5%;
Acetyl group hexapeptide -1:0.2-0.5%;
PEG-12 dimethyl silicone polymer: 1-1.5%;
GC-04:0.5-1%;
FCP-AK:0.5-1%;
PLANT 21:3-5%;
GL sweet dew ester: 2-3%;
E-Pearl PMF:2-3%;
AVH emulsifier: 1.5-2%;
Cetanol ethylhexoate: 3-4%;
Jojoba (SIMMONDSIA CHINENSIS) seed oil: 3-4%;
Saualane: 1.5-2%;
Queensland nut (MACADAMIA TERNIFOLIA) seed oil: 2-3%;
Multiflora rose (ROSA MULTIFLORA) fruit oil: 1-1.5%;
Essence: 0.05-0.1%;
Water: 52.9-67.65%;
The ingredient of the SOD whitening ferment powder are as follows: Bacillus acidi lactici/pomegranate (PUNICA GRANATUM) fruit tunning mentions Take object, the ingredient of the GC-04 are as follows: decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone;The component of the FCP-AK are as follows: Hydrolytic collagen/dipeptides -1;The ingredient of the PLANT 21 are as follows: butanediol, golden yellow chamomile (CHRYSANTHELLUM INDICUM) extract, peppermint (MENTHA ARVENSIS) leaf extract, aloe barbadensis Miller (ALOE BARBADENSIS) extract Object, kuh-seng (SOPHORA ANGUSTIFOLIA) root extract, Pelargonium roseum (PELARGONIUM GRAVEOLENS) are extracted Object;The ingredient of the GL sweet dew ester are as follows: trimethylpentanediol/adipic acid/glycerin crosspolymers;The E-Pearl PMF's Ingredient are as follows: water/poly methyl silsesquioxane/dimethyl silicone polymer/isohexadecane/16 octadecyl methyl siloxanes/ PEG-40 stearate ester/- 2/ stereth -21 of stereth;The ingredient of the AVH emulsifier are as follows: Sodium Polyacrylate/ Ethylhexyl stearate/trideceth -6.
In the present invention dipropylene glycol, that is, dipropylene glycol can also in a variety of different cosmetics applications as coupling agent and Moisturizer.This raw material has good moisture, and oil and hydrocarbon are total to molten ability, and smell is slight, pierces to skin Swash property very little.Isomer is evenly distributed unanimously, and quality is splendid.
Propylene glycol can be used as wetting agent with glycerol or sorbierite cooperation in cosmetics, toothpaste and perfumed soap in the present invention.? It is used as damping, even hair agent in hair dye, also serves as antifreezing agent, be also used to glassine paper, plasticizer and pharmaceuticals industry.
Glycerol is colourless sweet clear and bright thick liquid in the present invention.It is odorless.There is warm sweet taste.It can be used as solvent, lubricant, medicine Agent and sweetener.
SOD whitening ferment powder is also known as the extraction of Bacillus acidi lactici/pomegranate (PUNICA GRANATUM) fruit tunning in the present invention Object, tunning and extract are all mainly lactic acid.Additional some protease, vitamin series, organic matter (alcohol, phenol, insatiable hunger And fatty acid) etc., depending on fermentation material and extraction process, component content is more, is the non-defective unit of natural whiting ingredient.Except nutrition is rich It is rich outer.Main function is embodied in the following: 1. lactic acid play the role of good cutin-softening, there is fabulous smooth tender skin Effect, effect are well suited for that scalp is anti-dandruff and Oily it may be said that get instant result.2. good moistening effect, a small amount of addition is just There is the effect of good moisturizing skin.
Vitamin B3 is also known as niacinamide, as a kind of medical components have very high safety and clinic skin The basic vitamins replenishers of one of section's treatment, are ready for use on treatment photosensitive dermatitis, acne etc. relatively broadly.In recent years Come research have shown that, it inhibit melanin pigmentation, in terms of also have good curative effect;Based on this feature, niacinamide Further extension has been obtained in the application of cosmetic field, other than traditional whitening effect, also be used to reduce raw At the melanin of, precipitating, its transfer to cells of superficial layer is obstructed, accelerate that cell metabolism, to accelerate melanin horn cell de- It falls.Niacinamide is able to maintain that skin water content, promotes skin corium microcirculation.Niacinamide can also greatly reduce or to eliminate skin old Change phenomenon, for example wrinkle, peeling, pore are coarse etc., reduce injury of the free radical to skin, play pre- anti-aging, repair skin The effect obscure with face is reduced.Niacinamide can promote hair follicle blood circulation, and then promote natural on-off cycles of hair growth, prevent hair loss.
Arbutin is also known as Arbutin, can significantly inhibit accumulation of the tyrosinase in cortex, has Bleachability effect to skin, It can be used for preventing skin splash and freckle, effect is better than kojic acid and ascorbic acid.Restraint ratio B of the α type to tyrosinase activity About 10 times by force of type.There is research to think that the mechanism of action of arbutin is identical as quinhydrones, because of arbutin energy in the presence of appropriate acid, enzyme The free quinhydrones of release, therefore arbutin is not sufficiently stable in cream kind cosmetics as quinhydrones.Although arbutin has whitening Effect, but dosage improper (content is greater than 7%) may promote the generation of melanin instead.It can inhibit egg when arbutin experiment in vitro The degradation of white matter such as insulin etc. can mitigate and reduce the stimulation of surfactant or hair dye to skin and hair, equally It can promote dermal cell growth and help healing of wound.The Skin Cell in vitro culture experiment of people shows the micro presence of arbutin When (10-3mmol/L), vitro growth rates are significantly improved, and have nursing function to skin.
Dipotassium glycyrrhizinate is used as skin conditioning agent, predominantly the glycyrrhizin (glycyrrhizic acid) of Radix Glycyrrhizae root and stem Ingredient is suitble to anaphylaxis skin, anti-irritant and oil-control, moves back red and swollen antiphlogistic healing effect.Can effectively prevent skin it is stimulated when it is sensitive Inflammation phenomenon.Inflammation caused by counterglow has anti-inflammatory sedation, is commonly used for antiallergy and repairs in cosmetics.
Nonapeptide -1 is by arginine, lysine, methionine, phenylalanine, proline, tryptophan and valine in the present invention Composition, primary efficacy is bright color.It to Mcl-R have high compatibility, by with α-MSH competitive binding MCl-R receptor, The generation for further preventing tyrosinase, causes melanin production to receive inhibition, to reduce melanin pigmentation.
Acetyl group hexapeptide -1 is α-MSH bionic peptide in the present invention, is the agonist of α-MSH a kind of, by adjust by The synthesis of body MCl-R activity promotion melanin.It can be used as natural sun-screening agent, can enhance skin to ultraviolet radiation resisting Ability avoids skin from symptom of erythema occur, promotes light protection and anti-inflammatory effect, while can also promote adding for hair color Deep and reverse grey hair.
ES-5373 component is PEG-12 dimethyl silicone polymer in the present invention, is a kind of different polymerization degree chain structure Polysiloxane is that outstanding assistant for emulsifying agent and lubrication skin do agent.
GC-04 contains natural fatty acid glyceride, decoyl hydroximic acid and parahydroxyacet-ophenone in the present invention, wherein glycerol Aliphatic ester is a kind of active skull cap components being present in human breast milk, can enhance newborn infant diseases resistance and immunity, The mild polarity of skin is good, inhibits bacterium to agree yeast increment activity, also there is moisturizing, emulsification, moisturizing, wetting and Sage Extract etc. Effect;Parahydroxyacet-ophenone be present in compositae plant artemisia scoparia (Artemisia scoparia Waldst.et kit.) stem, Leaf and the anti-wormwood artemisia of mattress (A.capillaris Thunb.), Luo Mo section plant kerr tylophora root (Tylophora Kerrii It is natural antioxidant in the plants such as root Craib);Decoyl hydroximic acid is a no added preservative, its energy bactericidal, Solubilized hydrotropy.
FCP-AK component is hydrolytic collagen and dipeptides -1 in the present invention, and collagen is a kind of high molecular functional albumen Matter, it is the chief component of skin, accounts for the specific gravity of dermal layer of the skin 80%.
Deionized water is solvent in the present invention.
PLANT 21 is by water, butanediol, glycerol, golden yellow chamomile (CHRYSANTHELLUM INDICUM) in the present invention Extract, peppermint (MENTHA ARVENSIS) leaf extract, aloe barbadensis Miller (ALOE BARBADENSIS) extract, kuh-seng (SOPHORA ANGUSTIFOLIA) root extract, Pelargonium roseum (PELARGONIUM GRAVEOLENS) extract, dent It releives anti-sensitizer made of amaranth (PORTULACA OLERACEA) extract, sodium benzoate, potassium sorbate compounding.Golden yellow chamomile (Shu Min, maintenance sensitivity skin reduce rubescent antipruritic, promotion wound healing and skin regeneration), dried peppermint leaf (inhibits and paralysis is felt Nerve endings, can be used as counter-stimulus has antiallergy and itching-relieving action to pruitus), (antibacterial is sun-proof, nourishes rough skin for aloe Accelerate skin metabolism, enhancing skin elasticity), radix sophorae (rich in alkaloids antiallergies such as matrine and oxymatrines, resists It is scorching, to improve immunity, desinsection antipruritic), (fish pelargonium is the tonic of nervous system to fish pelargonium, can put down and comfort anxiety, dejected, moreover it is possible to mention Vibration mood.Mental recovery is allowed to balance, and since it can also influence adrenal cortex, it can relieve pressure.)
GL sweet dew ester ingredient is base pentanediol/adipic acid/glycerin crosspolymers in the present invention, is a moisturizer, has Moisturizing and increase lubrication sense effect.
E-Pearl PMF is by water, polyphenylsilsesquioxane, dimethyl silicone polymer, isohexadecane, whale in the present invention The lotion that wax stearyl polymethyl siloxane, PEG-40 stearate, stereth -2, stereth -21 form, is one Non-ionic silicone lotion of the kind containing poly methyl silsesquioxane, poly methyl silsesquioxane, dimethyl silicone polymer, can Outstanding pliability, moisture retention, desalination wrinkle and promotion whiteness are provided.
The cream that AVH emulsifier is made of Sodium Polyacrylate, ethylhexyl stearate, trideceth -6 in the present invention Agent.There is excellent emulsification thickening power to water oil.
UN-258 seabird oil, that is, cetanol ethylhexoate in the present invention.Cetanol ethylhexoate is commonly called as seabird feather Oil, the especially excellent emollients of waterproof performance have gas permeability and spreadability good, not sticky, have thickening efficiency, can moisten soft The advantages of soft skin.It can be applied to lipstick and make colorant dispersant and basic finish, glossy dose of lipstick, brilliantine agent, cream emulsion Softening agent.
Saualane is synthesized in the present invention, saualane is that rare chemical stability is high, and the splendid animal fat of use feeling is right Skin has preferable compatibility, will not cause allergy and stimulation, and other active components in formula can be accelerated to permeate into skin; With lower polarity and medium spreadability, and pure, colourless, free from extraneous odour
Oil of Queensland nut (MACADAMIA TERNIFOLIA) the seed oil containing a large amount in the present invention, especially to be rich in insatiable hunger With the characteristics of fatty acid, based on oleic acid and palmitinic acid, it is the preferable edible nut of quality in the world, is known as " dry fruit queen " The laudatory title of " king of world's nut ", macadimia nut oil can prevent heart disease, high natural of this monounsaturated fatty acids content Vegetable oil, the lipid-metabolism for being adjustable and controlling blood glucose level, improve diabetic are the good fat supplements of diabetic Source.Can also effective preserving moisture and protecting skin, be good sun-proof, skin-protection product.
There is rose hip oil in the present invention strengthens tissue effect, generates the effect of active tissue, readily permeable skin corium is protected It is wet, the effect of promoting skin smooth whitening.To cytothesis, maintenance and healing play the role of it is splendid.It can make skin-color plain Change, reappears homogeneous hue, keep skin smooth.It is able to maintain skin cleaning, and soft, soft, wet, deflation is solid, rich in bullet The effect of property, Feng Li.Effect is more especially shown in general coarse skin.
Essence in the present invention is tarted up for cosmetics.
The two of task of the present invention realize by following technical solution:
A kind of a kind of above-mentioned preparation method of the whitening and spot eliminating cream of releiving of the ferment powder containing whitening, comprising the following steps:
S1. dipropylene glycol, propylene glycol, glycerol, the SOD whitening ferment powder, niacinamide, bear of molten A phase are weighed by quality proportioning Fruit glycosides, dipotassium glycyrrhizinate, nonapeptide -1, acetyl group hexapeptide -1, PEG-12 dimethyl silicone polymer, GC-04, FCP-AK, water, PLANT 21, GL sweet dew ester, E-Pearl PMF, AVH emulsifier sequentially add water phase pot and stir evenly.
S2. cetanol ethylhexoate, the Jojoba (SIMMONDSIA CHINENSIS) of molten B phase are weighed by quality proportioning Seed oil, saualane, Queensland nut (MACADAMIA TERNIFOLIA) seed oil, multiflora rose (ROSA MULTIFLORA) fruit oil add Enter in oily phase pot, is mixed evenly.
S3. material in A phase is pumped into emulsion pot and is stirred
During S4.A phase materials persistently stir, B phase materials are pumped into A phase emulsion pot and obtain Material C, stirred 3 minutes, high speed It homogeneous 5 minutes, persistently stirs evenly.
S5. Material C is added in essence by quality proportioning, can discharged after mixing evenly.
Whitening and spot eliminating cream of releiving has following effect:
1. the anti-inflammatory anti-anaphylaxis itching-relieving action of pair skin, peppermint (MENTHA ARVENSIS) leaf extract in PLANT 21 can Antipruritic with antiallergic, Pelargonium roseum (PELARGONIUM GRAVEOLENS) extract can improve myogenic, aloe barbadensis Miller (ALOE BARBADENSIS) extract can moisten moisturizing, and purslane (PORTULACA OLERACEA) extract can be with antiallergic Anti-inflammatory, golden yellow chamomile (CHRYSANTHELLUM INDICUM) extract can releive reparation, kuh-seng (SOPHORA ANGUSTIFOLIA) root extract can promote immunity, enhance the effect of skin repair.
2. pair skin skin whitening, moisturizing acts on, SOD whitening ferment powder is the non-defective unit of natural whiting ingredient.In addition to full of nutrition. Main function is embodied in the following: 1. lactic acid play the role of good cutin-softening, there is the effect of fabulous smooth tender skin, Effect is well suited for Oily it may be said that get instant result.2. good moistening effect, a small amount of addition just has good moisturizing The effect of skin.
3. health care effect of dispelling spots is tied this is because -1 couple of Mcl-R of nonapeptide has high compatibility by competing with α-MSH MCl-R receptor is closed, the generation of tyrosinase is further prevented, causes melanin production to receive inhibition, to reduce melanin It is calm.Accumulation of the tyrosinase in cortex can be significantly inhibited by arbutin again, have Bleachability effect to skin, skin can be prevented Colour of skin spot and freckle, in addition to this, niacinamide can greatly reduce or eliminate skin ageing phenomenon, for example wrinkle, peeling, pore are thick It is big etc., injury of the free radical to skin is reduced, pre- anti-aging is played, repair skin and reduces the obscure effect of face.
Above description is only embodiments herein and the explanation to institute's application technology principle.Those skilled in the art answer Work as understanding, invention scope involved in the application, however it is not limited to technical solution made of the specific combination of above-mentioned technical characteristic, It should also cover in the case where not departing from the inventive concept simultaneously, carry out any group by above-mentioned technical characteristic or its equivalent feature The other technical solutions closed and formed.Such as features described above and (but being not limited to) disclosed herein have the skill of similar functions Art feature is replaced mutually and the technical solution that is formed.

Claims (2)

1. a kind of whitening and spot eliminating cream of releiving of ferment powder containing whitening, which is characterized in that by the component production of following quality proportionings At:
Dipropylene glycol: 2-3%;
Propylene glycol: 2-3%;
Glycerol: 0.5-1%;
SOD whitening ferment powder: 2-2.5%;
Niacinamide: 2-2.5%;
Arbutin: 2-2.5%;
Dipotassium glycyrrhizinate: 0.4-0.5%;
Nonapeptide -1:0.2-0.5%;
Acetyl group hexapeptide -1:0.2-0.5%;
PEG-12 dimethyl silicone polymer: 1-1.5%;
GC-04:0.5-1%;
FCP-AK:0.5-1%;
PLANT 21:3-5%;
GL sweet dew ester: 2-3%;
E-Pearl PMF:2-3%;
AVH emulsifier: 1.5-2%;
Cetanol ethylhexoate: 3-4%;
Jojoba (SIMMONDSIA CHINENSIS) seed oil: 3-4%;
Saualane: 1.5-2%;
Queensland nut (MACADAMIA TERNIFOLIA) seed oil: 2-3%;
Multiflora rose (ROSA MULTIFLORA) fruit oil: 1-1.5%;
Essence: 0.05-0.1%;
Water: 52.9-67.65%;
The ingredient of the SOD whitening ferment powder are as follows: Bacillus acidi lactici/pomegranate (PUNICA GRANATUM) fruit tunning extract, The ingredient of the GC-04 are as follows: decoyl hydroximic acid/glycerol caprylate/parahydroxyacet-ophenone;The component of the FCP-AK are as follows: hydrolysis Collagen/dipeptides -1;The ingredient of the PLANT 21 are as follows: butanediol, golden yellow chamomile (CHRYSANTHELLUM INDICUM) mention Take object, peppermint (MENTHA ARVENSIS) leaf extract, aloe barbadensis Miller (ALOE BARBADENSIS) extract, kuh-seng (SOPHORA ANGUSTIFOLIA) root extract, Pelargonium roseum (PELARGONIUM GRAVEOLENS) extract;It is described The ingredient of GL sweet dew ester are as follows: trimethylpentanediol/adipic acid/glycerin crosspolymers;The ingredient of the E-Pearl PMF are as follows: Water/poly methyl silsesquioxane/dimethyl silicone polymer/isohexadecane/16 octadecyl methyl siloxanes/PEG-40 is stearic Hydrochlorate ester/- 2/ stereth -21 of stereth;The ingredient of the AVH emulsifier are as follows: Sodium Polyacrylate/stearic acid ethyl Own ester/trideceth -6.
2. a kind of preparation method of the whitening and spot eliminating cream of releiving based on a kind of ferment powder containing whitening described in claim 1, feature It is, comprising the following steps:
S1. by quality proportioning weigh the dipropylene glycol of molten A phase, propylene glycol, glycerol, SOD whitening ferment powder, niacinamide, arbutin, Dipotassium glycyrrhizinate, nonapeptide -1, acetyl group hexapeptide -1, PEG-12 dimethyl silicone polymer, GC-04, FCP-AK, water, PLANT 21, GL sweet dew ester, E-Pearl PMF, AVH emulsifier sequentially add water phase pot and stir evenly.
S2. cetanol ethylhexoate, Jojoba (SIMMONDSIA CHINENSIS) seed of molten B phase are weighed by quality proportioning Oil, saualane, Queensland nut (MACADAMIA TERNIFOLIA) seed oil, multiflora rose (ROSA MULTIFLORA) fruit oil are added In oily phase pot, it is mixed evenly.
S3. material in A phase is pumped into emulsion pot and is stirred
During S4.A phase materials persistently stir, B phase materials are pumped into A phase emulsion pot and obtain Material C, stirred 3 minutes, high speed homogenization It 5 minutes, persistently stirs evenly.
S5. Material C is added in essence by quality proportioning, can discharged after mixing evenly.
CN201910045460.9A 2019-01-17 2019-01-17 A kind of whitening and spot eliminating cream and preparation method thereof of releiving of the ferment powder containing whitening Pending CN109620795A (en)

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Application publication date: 20190416