CN110227052A

CN110227052A - Face cream and preparation method thereof is repaired in a kind of moisturizing

Info

Publication number: CN110227052A
Application number: CN201910532839.2A
Authority: CN
Inventors: 王澍
Original assignee: Hangzhou Yuexuantang Cosmetics Co Ltd
Current assignee: Hangzhou Yuexuantang Cosmetics Co Ltd
Priority date: 2019-06-19
Filing date: 2019-06-19
Publication date: 2019-09-13

Abstract

The embodiment of the present application provides a kind of moisturizing and repairs face cream and preparation method thereof, is related to skin care field.The raw material for preparing that face cream is repaired in the moisturizing according to percent by weight includes: water, glycerol, butanediol, emulsifier, phytosphingosine, cholesterine, ceramide, Sodium Hyaluronate, pH adjusting agent, grease type emollient, antioxidant, biological carbohydrate gum -1, thallus laminariae extract etc..The preparation method that face cream is repaired in moisturizing includes: that butanediol, phytosphingosine, cholesterine, ceramide and glycerol, part water are formed the first water phase；The second water phase that Sodium Hyaluronate and part water are formed is added into the first water phase, dissolution obtains mixed phase；The dispersed phase oil phase that emulsifier is formed is added into mixed phase, the oily phase of grease type emollient formation is added after dissolution under agitation, be added after mixing it is remaining prepare raw material, and be uniformly mixed.Moisturizing reparation face cream is good to skin moisture-keeping, repairing effect, highly-safe, and it is low to prepare energy consumption.

Description

Face cream and preparation method thereof is repaired in a kind of moisturizing

Technical field

This application involves skin care fields, repair face cream and preparation method thereof in particular to a kind of moisturizing.

Background technique

Skin is the vitals of human body, and institutional framework is complicated, closely coupled with other organs of human body, plays barrier Effect, protects human body not by outside stimulus and injury.With the continuous innovation of skin care item and pharmaceutical technology, natural, safety, ring It protects, both effectiveness skin care item are increasingly by the welcome of consumer.

Skin care creams class product is the main product in skin care item, belongs to emulsification system, mainly includes grease, emulsification Agent, rheology control agent, moisturizer, preservative, antioxidant, essence, chelating agent, colorant and other active components.It wants at present Want that the skin care creams class product with multiple efficacies is made, inevitably needs to be added some chemistry that can generate stimulation to skin and make Agent；In addition, common emulsification system is O/W type or w/o type, it is typically prepared technique and is required to oil mutually pouring into water phase (O/W type) Or water phase pours into oily phase (w/o type) and carries out high speed homogenization emulsification, and uniform, fine and smooth, stable product, high speed homogenization could be made Emulsification needs high-energy to input, and energy consumption is higher.

Summary of the invention

Face cream and preparation method thereof is repaired in a kind of moisturizing of being designed to provide of the embodiment of the present application, to skin moisture-keeping, is repaired Multiple effect is good, highly-safe, and it is low to prepare energy consumption.

In a first aspect, the embodiment of the present application provides a kind of moisturizing reparation face cream, raw material is prepared according to weight percent Meter includes:

In the above-mentioned technical solutions, inventor, by the structure composition of simulated skin, grinds during realizing the application Study carefully the skin care ingredient for maintaining skin barrier structure, discovery skin care ingredient is broadly divided into two major classes: moisturizing ingredient and crease-resistant, anti-aging Ingredient.Wherein, the moisture-keeping system of skin is mainly made of water, lipid and natural moisturizing factor, and lipid includes ceramide, cholesteric Pure and mild free fatty acid etc..The application is mainly realized by following aspect to skin moisture-keeping, repairing effect:

(1) the application is by moisture absorption and water conservation collective effect, and realize moisture-keeping efficacy: glycerol is as the first moisturizer, cooperation The collective effects such as maize germ extract and the Sodium Hyaluronate of small molecule attract hydrone by adjusting osmotic pressure, make skin Skin cuticula keeps wet；It, can be in skin surface simultaneously using grease type emollient and the biological carbohydrate gum -1 of macromolecular structure One layer of protective film with height moisture-keeping function is formed, to improve the anti-dehydration ability of skin.And maize germ extract Use the usage amount of glycerol can be reduced under the premise of keeping identical moisture-keeping function, reduce final finished and give user's bring Greasy feeling.

(2) essence is concentrated by addition class skin lipid in the application, to improve skin moisturizing and phylactic power defensive power, the class of the application Skin lipid concentration essence includes the mixing concentrate of different ceramides, cholesterine, free fatty acid and phytosphingosine, energy Enough structures for forming similar keratoderma sebum film, play cooperative effect, it is quick to help improve skin for strong skin barrier function Sense.

(3) the application is rich by addition thallus laminariae extract and this kind of cutaneous gene factor of sargassum fusifome alcohol extracting thing The ester of algae containing opotism and Hijiki polysaccharide can reactivate 14 related genes in skin corium extracellular matrix, promote glue Former albumen, the synthesis of elastin laminin and link and the synthesis of hyaluronic acid and fibroblastic activity, to repair, draw Lift real face skin.

(4) the application can significantly repair skin, especially crease-resistant ingredient and opotism by adding a certain amount of crease-resistant ingredient Dish extract/sargassum fusifome alcohol extracting thing collective effect can be played to effective crease-resistant, the anti-wrinkle effect of skin.

(5) the application is rich in various amino acid, can mend by adding a certain amount of hydrolyzed vegetable protein, hydrolyzed vegetable protein Skin-nourishing is filled, skin nourishment is given, has good moistening effect to skin, while there is film forming, with the first moisturizer, class Skin lipid concentration essence is used in compounding, and can reach extraordinary moistening effect.

Therefore, the moisturizing reparation face cream of the application is suitble to different skin quality, while realizing moisturizing, passes through and promotes collagen egg The synthesis of white, elastin laminin, hyaluronic acid repairs skin to enhance skin barrier.And the application passes through different material It is applied in combination and realizes moisturizing, repairing effect, and avoid generating stimulation to skin greatly very much because of certain raw material additional amount.

In one possible implementation, ceramide includes:

Cer NP 0.005%-0.1%；

Cer AP II 0.005%-0.1%；And

Cer EOS 0.00001%-0.0001%.

In the above-mentioned technical solutions, Cer NP is a kind of lipid matter, artificial synthesized ingredient, it and constitute skin angle The structure of matter of matter layer is close, can penetrate into skin quickly, helps the update of skin natural containment, can promote Natural Water cooperation Water in balance and cuticula combines, and forms a kind of reticular structure, locks moisture.Cer AP II can improve sebum Inhibit active smegma while film, peeling off by scaling of skin makes the natural stripping process normalization of skin, allows flesh Skin water and oil balance；The natural sebum film of the intensive repair of skin of Cer EOS energy, strengthens the defensive enginery of skin surface barrier, has Good closure reduces moisture evaporation and is lost.The application using Cer NP, Cer AP II and Cer EOS this Three kinds of different ceramides play cooperative effect, form the structure of similar keratoderma sebum film with other raw materials, enhance Skin barrier function.

In one possible implementation, anti-wrinkle ingredient includes:

Argireline 0.000001%-0.001%；

- 5 0.000005%-0.001% of palmityl tripeptides；

Dipeptides diaminobutyryl benzyl amide diacetin 0.000005%-0.001%.

In the above-mentioned technical solutions, Argireline is a kind of neurotransmitter inhibition class victory peptide, and antiwrinkle active is high, secondary It acts on small；Palmityl tripeptides -5 promote skin cell growth, inhibit oxygen radical and hydroxyl radical free radical, promote stromatin The synthesis of (matrix protein) especially collagen, while being also possible to increase elastin laminin, hyaluronic acid, glycosaminoglycan With the generation of fibronectin；Dipeptides diaminobutyryl benzyl amide diacetin is a kind of synthesis victory for simulating calmette's serum Peptide can prevent the nerve conduction of acetylcholine, achieve the effect that relax one's muscles, so as to improve dynamic wrinkle.Acetyl group hexapeptide- 8, palmityl tripeptides -5, dipeptides diaminobutyryl benzyl amide diacetin belong to crease-resistant ingredient, repair in face cream and add in moisturizing Enter crease-resistant ingredient appropriate as skin conditioning agent, crease-resistant, the anti-aging effects of product can be further enhanced.

In one possible implementation, emulsifier includes the smooth tristearate of sorb, -3 methyl two of polyglycereol At least one of stearate；And/or pH adjusting agent includes at least one of sodium hydroxide, citric acid；And/or antioxygen Agent includes at least one of tocopherol, ascorbyl palmitate, ascorbic acid.

In the above-mentioned technical solutions, using the smooth tristearate of sorb, polyglycereol-3-methyl distearate conduct Emulsifier can make immiscible Aqueous Phase Raw Material and oily phase raw material form stable creams when mixing, use convenient for consumer. Moisturizing reparation can be slowed down as antioxidant using at least one of tocopherol, ascorbyl palmitate, ascorbic acid Active component in face cream is oxidized, to ensure effect.

In one possible implementation, grease type emollient include dimethyl silicone polymer, dimethyl silicone polymer/ Vinyl dimethicone cross polymer, dimethiconol, ring five dimethyl silicone polymer, cetanol, hydrogen Change at least one of sodium cocoglyceryl esters.

In the above-mentioned technical solutions, can form one layer in skin surface using the oil property of grease type emollient has The protective film of height moisture-keeping function, to improve the anti-dehydration ability of skin.

In one possible implementation, the second moisturizer that raw material further includes 1%-5% is prepared；And/or preparation Raw material further includes the surfactant of 0.1%-0.5%；And/or prepare the thickener that raw material further includes 0.5%-1%；With/ Or, preparing the film forming agent that raw material further includes 0.05%-0.3%.

In the above-mentioned technical solutions, it is repaired in face cream in moisturizing and the second moisturizer appropriate is added, it can be further enhanced Moistening effect；It is repaired in face cream in moisturizing and surfactant appropriate is added, emulsification can be further enhanced, especially to this Apply for that the plurality of raw materials selected solubilising, emulsifying effectiveness are good；It is repaired in face cream in moisturizing and thickener appropriate is added, can further increased Stiff stability especially protects stablizing for active constituent；Moisturizing repair face cream in film forming agent appropriate is added, be in order into One step prevents the loss of moisture, to enhance moistening effect.

In one possible implementation, the preservative that raw material further includes 0.2%-0.9% is prepared, preservative includes benzene At least one of oxyethanol, methyl hydroxybenzoate, pungent glycol, Sensiva SC50.

In the above-mentioned technical solutions, moisturizing repair face cream in preservative appropriate is added, can postpone microorganism growth or Corruption caused by chemical change, to greatly extend the shelf-life of product.

In one possible implementation, the stabilizer that raw material further includes 0.001%-0.05%, stabilizer packet are prepared Include xanthan gum.

In the above-mentioned technical solutions, it is repaired in face cream in moisturizing and stabilizer appropriate is added, the stability of system can be enhanced, Guarantee that it plays effect.

In one possible implementation, the chelating agent that raw material further includes 0.05%-0.3% is prepared；And/or preparation Raw material further includes the aromatic of 0.01%-0.1%；And/or prepare the colorant that raw material further includes 0.0001%-0.001%.

In the above-mentioned technical solutions, it is repaired in face cream in moisturizing and chelating agent appropriate is added, certain originals can be further enhanced The stability of material；It is repaired in face cream in moisturizing and aromatic appropriate is added, fragrance can cover uncomfortable taste, increase the pleased of user Happy sense；It is repaired in face cream in moisturizing and colorant appropriate is added, adjust the color of product.

Second aspect, the embodiment of the present application provide a kind of preparation method of moisturizing reparation face cream that first aspect provides, Itself the following steps are included:

By butanediol, phytosphingosine, cholesterine, ceramide and at least partly glycerol, part water formed the first water phase；

The second water phase that Sodium Hyaluronate and remaining part water are formed is added into the first water phase, dissolution is mixed Phase；

At least partly pH adjusting agent is first added into mixed phase, then adds emulsifier and amount of grease class moisturizing dosage form At dispersed phase oil phase, the oily phase that remaining at least partly grease type emollient is formed is added after dissolution under agitation, mixes Addition is remaining after closing uniformly prepares raw material, and is uniformly mixed.

In the above-mentioned technical solutions, white shape gel rubber system first is made in continuous phase water phase, then oil is added under agitation Phase, is not necessarily to homogeneous, and the product of formation is O/W type emulsification system.Power save mode is used in whole preparation process, is saved and is needed height The face cream stablized, uniformly, fine and smooth can be made only by stirring in the high speed homogenization emulsifying step of energy input.

Specific embodiment

It, below will be in the embodiment of the present application to keep the purposes, technical schemes and advantages of the embodiment of the present application clearer Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, according to normal conditions or manufacturer builds The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase Product.

Face cream and preparation method thereof is repaired to the moisturizing of the embodiment of the present application below to be specifically described.

It should be noted that the "and/or" in the application, such as " option A and/or option b ", each meaning individually to be Option A individually for option b, option A adds option b, three kinds of modes.

The embodiment of the present application provides a kind of moisturizing reparation face cream, and preparing raw material according to percent by weight includes: The water of 70%-80%, the glycerol of 5%-10%, the butanediol of 3%-8%, the emulsifier of 4%-13%, 0.01%-0.1% The hyalomitome of phytosphingosine, the cholesterine of 0.005%-0.1%, the ceramide of 0.01%-0.21%, 0.01%-0.1% Sour sodium, the pH adjusting agent of 0.05%-0.3%, the grease type emollient of 5%-15%, 0.006%-0.155% antioxidant, The biological carbohydrate gum -1 of 0.005%-0.1%, the thallus laminariae extract of 0.005%-0.1%, 0.005%-0.1% sargassum fusifome The anti-wrinkle ingredient of alcohol extracting thing, the hydrolyzed vegetable protein of 0.00001%-0.0005% and 0.00001%-0.003%.It can Choosing, moisturizing repair face cream prepare raw material according to percent by weight include: the water of 73%-77%, 6%-8% glycerol, The cholesteric of the butanediol of 5%-7%, the emulsifier of 5%-10%, the phytosphingosine of 0.01%-0.1%, 0.005%-0.1% Alcohol, the ceramide of 0.05%-0.15%, the Sodium Hyaluronate of 0.01%-0.1%, 0.05%-0.3% pH adjusting agent, The grease type emollient of 5%-8%, the antioxidant of 0.006%-0.155%, 0.005%-0.1% biological carbohydrate gum -1, The thallus laminariae extract of 0.005%-0.1%, the sargassum fusifome alcohol extracting thing of 0.005%-0.1%, 0.00001%-0.0005% Hydrolyzed vegetable protein and 0.00001%-0.003% anti-wrinkle ingredient.

Herein it is worth mentioning that the extracting method of sargassum fusifome alcohol extracting thing:

(1) ethanol solution of sargassum fusifome and 30%-60% are put into together in preset pot for solvent extraction, weight proportion 1: 10-15；

(2) it in pot for solvent extraction under negative pressure (- 0.05--0.2MPa) environment, impregnates 30 minutes；

(3) leaching liquor in pot for solvent extraction is extracted in concentration tank and is concentrated；

(4) concentrate is taken out after concentration is completed；

(5) concentrate is put into vacuum freeze dry；

(6) it after moisture is lower than 15%, takes out and crushes.Obtain sargassum fusifome alcohol extracting thing.

In some alternative embodiments, ceramide includes: the Cer NP of 0.005%-0.1%；0.005%- 0.1% Cer AP II；And the Cer EOS of 0.00001%-0.0001%, i.e., Cer NP, which accounts for, prepares raw material Weight percent is 0.005%-0.1%, and it is 0.005%-0.1%, mind that Cer AP II, which is accounted for and prepared the weight percent of raw material, Accounting for through amide 1 and preparing the weight percent of raw material is 0.00001%-0.0001%.Further alternative, ceramide includes: The Cer NP of 0.025%-0.07%；The Cer AP II of 0.025%-0.07%；And 0.00001%-0.0001% Cer EOS.

In some alternative embodiments, anti-wrinkle ingredient includes: the Argireline of 0.000001%-0.001%； The palmityl tripeptides -5 of 0.000005%-0.001%；And the dipeptides diaminobutyryl benzyl acyl of 0.000005%-0.001% It is 0.000001%-0.001%, palmityl three that amine diacetin, i.e. Argireline, which account for and prepare the weight percent of raw material, It is 0.000005%-0.001%, dipeptides diaminobutyryl benzyl amide oxalic acid that peptide -5, which accounts for and prepares the weight percent of raw material, It is 0.000005%-0.001% that salt, which accounts for and prepares the weight percent of raw material,.Further alternative, anti-wrinkle ingredient includes: The Argireline of 0.0001%-0.001%；The palmityl tripeptides -5 of 0.00005%-0.001%；And The dipeptides diaminobutyryl benzyl amide diacetin of 0.00005%-0.001%.

In some alternative embodiments, emulsifier includes that the smooth tristearate of sorb, -3 methyl two of polyglycereol are hard At least one of resin acid ester；And/or pH adjusting agent includes at least one of sodium hydroxide, citric acid；And/or it is anti-oxidant Agent includes at least one of tocopherol, ascorbyl palmitate, ascorbic acid (vitamin C).In some illustrative realities It applies in example, antioxidant includes the tocopherol of 0.005%-0.1%；The ascorbyl palmitate of 0.001%-0.05%； The ascorbic acid of 0.0001%-0.001%.

In some alternative embodiments, grease type emollient includes dimethyl silicone polymer, dimethyl silicone polymer/second Alkenyl Dimethicone Crosspolymer, dimethiconol, ring five dimethyl silicone polymer, cetanol, hydrogenation At least one of sodium cocoglyceryl esters.In some exemplary embodiments, grease type emollient includes the poly- of 0.5%-3% Dimethyl siloxane；The Dimethicone/Vinyl Dimethicone cross-linked polymer of 0.1%-0.5%； The dimethiconol of 0.01%-0.1%；The ring five dimethyl silicone polymer of 3%-5%；The cetanol of 1%-3%； One of hydrogenated coco-glyceride class of 0.5%-3%.In some other exemplary embodiment, the grease of 1%-2% Class emollient includes the cetanol of dimethyl silicone polymer, the ring five dimethyl silicone polymer of 3%-8%, 1%-5%.

In some alternative embodiments, the second moisturizer that raw material further includes 1%-5% is prepared, such as, but not limited to 1%, 2%, 3%, 4%, 5%；Optionally, the second moisturizer includes -8/5/3 glycerol of PEG/PPG/ polytetramethylene glycol, polyethylene glycol - At least one of 8, illustratively, the second moisturizer include 1%-5% -8/5/3 glycerol of PEG/PPG/ polytetramethylene glycol, The polyethylene glycol-8 of 0.01%-0.1%；And/or the surfactant that raw material further includes 0.1%-0.5% is prepared, such as but not It is limited to 0.1%, 0.2%, 0.3%, 0.4%, 0.5%；Optionally, surfactant includes lauroyl dilactic acid sodium；With/ Or, the thickener that raw material further includes 0.5%-1% is prepared, such as, but not limited to 0.5%, 0.7%, 0.9%, 1%；Optionally, Thickener includes carbomer；And/or the film forming agent that raw material further includes 0.05%-0.3% is prepared, such as, but not limited to 0.05%, 0.15%, 0.25%, 0.3%；Optionally, film forming agent includes Sodium Polyacrylate.

In some alternative embodiments, the preservative that raw material further includes 0.2%-0.9% is prepared, such as, but not limited to 0.2%, 0.4%, 0.6%, 0.9%；Preservative include Phenoxyethanol, methyl hydroxybenzoate, pungent glycol, in Sensiva SC50 extremely Few one kind.In some exemplary embodiments, preservative includes the Phenoxyethanol of 0.1%-0.4%；0.1%-0.3%'s Methyl hydroxybenzoate；The pungent glycol of 0.000001%-0.0001%；The Sensiva SC50 of 0.05%-0.1%.

In one possible implementation, the stabilizer that raw material further includes 0.001%-0.05% is prepared, such as but not It is limited to 0.001%, 0.01%, 0.03%, 0.05%, stabilizer includes xanthan gum.

In one possible implementation, the chelating agent that raw material further includes 0.05%-0.3% is prepared, such as but unlimited In 0.05%, 0.15%, 0.25%, 0.3%, optionally, chelating agent includes disodium ethylene diamine tetraacetate (EDETATE SODIUM)；With/ Or, the aromatic that raw material further includes 0.01%-0.1% is prepared, such as, but not limited to 0.01%, 0.05%, 0.1%, optionally, Aromatic includes (daily) essence；And/or the colorant that raw material further includes 0.0001%-0.001% is prepared, such as but unlimited In 0.0001%, 0.0004%, 0.0007%, 0.001%, optionally, colorant includes the CI of 0.00005%-0.0005% 19140 (lemon yellow, yellow 4)；The CI 15985 (sunset yellow, Sunset Yellow FCF) of 0.00005%-0.0005%.

The embodiment of the present application also provides the preparation methods that face cream is repaired in a kind of above-mentioned moisturizing comprising following steps:

By butanediol, phytosphingosine, cholesterine, ceramide and at least partly glycerol, part water formed the first water phase.

The second water phase that Sodium Hyaluronate and part water are formed is added into the first water phase, dissolution obtains mixed phase.

At least partly pH adjusting agent is first added into mixed phase, optionally, sodium hydroxide is first added, then adds emulsification The dispersed phase oil phase that agent and amount of grease class emollient are formed is (after emulsifier and grease type emollient heating for dissolving, in liquid State), the oily phase that remaining at least partly grease type emollient is formed is added after dissolution under agitation, i.e., under agitation Oil is mutually poured into water phase, be added after mixing it is remaining prepare raw material, and be uniformly mixed.Optionally, in 75-80 DEG C of item of high temperature Under part after dispersed phase oil is mutually completely dissolved, then oily phase is added under rapid mixing conditions, stirs, in the present embodiment The revolving speed quickly stirred refer to 1000 revs/min or more.

In the application, first by continuous phase water phase: the first water phase and the second water phase are added, and pH regulator hydrogen-oxygen is then added Change sodium, system can be in gel state；Dispersed phase oil phase is added, makes oil droplet emulsification, be suspended in gel, add oily phase and its His raw material, can form stable creams product, be not necessarily to homogeneous.

In some alternative embodiments, addition is remaining prepares raw material, and further comprising the steps of after mixing:

It is cooled to 20-30 DEG C；

Filtering can generally be filtered using 100 mesh filter screens；

Before Material discharging, Q.C. sampling carries out semi-finished product detection；

After the assay was approved, filling, packed products carry out product inspection, qualification factory to Material.

In some alternative embodiments, the first water phase (i.e. A phase) the preparation method comprises the following steps: by butanediol, phytosphingosine, Cholesterine, ceramide and at least partly glycerol, part water (as solvent) are mixed to form water phase, optionally, can also be added A certain amount of preservative, chelating agent etc..Since phytosphingosine, cholesterine, ceramide belong to active constituent, in order to avoid Active constituent inactivates in process for preparation, and phytosphingosine, cholesterine, ceramide can be configured to surely by the present embodiment in advance Fixed skin conditioner, optionally, first by phytosphingosine, cholesterine, ceramide, part water (as solvent), Yi Jibiao Face activating agent, preservative, stabilizer, thickener, which are uniformly mixed, obtains a kind of skin conditioner system.It is, moreover, an optional that this implementation Preservative and chelating agent can also be configured to a kind of preservative system in advance by example.The present embodiment is in advance by part material and other Additive is configured to stable material system, not only can guarantee the preservation of active constituent, but also additive is made with active constituent For raw material addition, it will continue to play a role, constitute last emulsification system, compared to the side for being directly individually added into all raw materials The feed way of formula, the application is not only convenient for the preservation of active constituent, and the stability of this system gradually formed is stronger.

In an exemplary embodiment, by the percent by weight for preparing raw material, A phase includes following raw material:

1, solvent: water 60%-62%；

2, moisturizer: glycerol 5%-10%；

3, moisturizer: butanediol 3%-8%；

4, skin conditioning agent: water 3%-4%；Lauroyl dilactic acid sodium 0.1%-0.5%；Phytosphingosine 0.01%- 0.1%；Cer NP 0.005%-0.1%；Phenoxyethanol 0.03%-0.1%；Cer AP II 0.005%-0.1%； Cholesterine 0.005%-0.1%；Xanthan gum 0.001%-0.05%；Sensiva SC50 0.03%-0.5%；Carbomer 0.2%-0.5%；Cer EOS 0.00001%-0.0001%；

5, preservative: Phenoxyethanol 0.04%-0.3%；

6, preservative: methyl hydroxybenzoate 0.1%-0.3%；EDETATE SODIUM 0.05%-0.3%；Sensiva SC50 0.02%- 0.5%.

In some alternative embodiments, the second water phase (i.e. B phase) the preparation method comprises the following steps: by Sodium Hyaluronate and remaining Part water is mixed to form water phase, optionally, a certain amount of thickener, film forming agent can also be added；It is further alternative, in order to protect The stability of film forming agent is demonstrate,proved, film forming agent first can form film forming agent system with remaining part water, then mix shape with other raw materials At the second water phase.

In an exemplary embodiment, by the percent by weight for preparing raw material, B phase includes following raw material:

7, thickener: carbomer 0.3%-0.5%；

8, film forming agent: Sodium Polyacrylate 0.05%-0.3%；Water 1%-2%；

9, skin conditioning agent: Sodium Hyaluronate 0.01%-0.1%.

In some alternative embodiments, dispersed phase oil phase (i.e. C phase) the preparation method comprises the following steps: by emulsifier and amount of grease Class emollient is mixed to form dispersed phase oil phase, optionally, a certain amount of surfactant can also be added.

In an exemplary embodiment, by the percent by weight for preparing raw material, C phase includes following raw material:

10, grease type emollient: ring five dimethyl silicone polymer 3%-5%；

11, emulsifier: the smooth tristearate 3%-8% of sorb；

12, grease type emollient: cetanol 1%-3%；

13, emulsifier: polyglycereol -3- methyl distearate 1%-5%；

14, grease type emollient: hydrogenated coco-glyceride class 0.5%-3%；

In some alternative embodiments, oily phase (D phase) the preparation method comprises the following steps: by remaining at least partly grease type moisturizing Agent is mixed to form oily phase.Optionally, different grease type emollients is mixed to form grease type emollient system in advance, then will not Same grease type emollient system mixes.

In an exemplary embodiment, by the percent by weight for preparing raw material, D phase includes following raw material:

15, emollient: dimethyl silicone polymer 0.25%-1.5%；Dimethyl silicone polymer/vinylpolydimethyl silicon Oxygen alkane cross-linked polymer 0.1%-0.5%；

16, emollient: dimethyl silicone polymer 0.25%-1.5%；Dimethiconol 0.01%-0.1%.

In some alternative embodiments, E phase made of raw material first can also be prepared by remaining, then added, E phase The preparation method comprises the following steps: by biological carbohydrate gum -1, thallus laminariae extract, sargassum fusifome alcohol extracting thing, hydrolyzed vegetable protein, anti-wrinkle ingredient, Partial glycerol and part water are mixed, and optionally, a certain amount of antioxidant, the second moisturizer, other function can also be added Skin conditioning agent, aromatic, the colorant etc. of energy.It is further alternative, in order to guarantee the stability of the second moisturizer, first by Second moisturizer and stabilizer first can also be formed moisturizer body at moisturizer system by two moisturizer and Partial Antioxidation dosage form System, concrete condition are determined according to the type of the second moisturizer.In some alternative embodiments, in order to guarantee biological carbohydrate gum -1 Biological carbohydrate gum -1 is mixed to form a kind of skin conditioning agent system with preservative, part water in advance by activity；In order to guarantee thallus laminariae Thallus laminariae extract and glycerol (moisturizer), part water are formed one kind in advance by the activity of extract and sargassum fusifome alcohol extracting thing Skin conditioning agent system；In order to guarantee the activity of hydrolyzed vegetable protein, in advance by hydrolyzed vegetable protein and partial glycerol (moisturizing Agent), part water form a kind of skin conditioning agent system；In order to guarantee the skin conditioning agent of the other functions such as the anti-wrinkle ingredient being added Activity, the skin conditioning agent and partial glycerol or preservative, part water can be mixed to form a kind of skin conditioning agent in advance System.

In an exemplary embodiment, by the percent by weight for preparing raw material, E phase includes following raw material:

17, moisturizer: -8/5/3 glycerol 1%-5% of PEG/PPG/ polytetramethylene glycol；Tocopherol (vitamin E) 0.0025%- 0.05%；

18, skin conditioning agent: water 1%-2%；Phenoxyethanol 0.03%-0.1%；Biological -1 0.005%- of carbohydrate gum 0.1%；

19, skin conditioning agent: glycerol 1%-1.5%；Water 1%-2%；Thallus laminariae extract 0.005%-0.1%；Sheep dwells Dish extract 0.005%-0.1%；

20, antioxidant: polyethylene glycol-8 0.01%-0.1%；Tocopherol 0.0025%-0.05%；Ascorbic acid palm Acid esters 0.001%-0.05%；Ascorbic acid (vitamin C) 0.0001%-0.001%；Citric acid 0.0001%-0.001%；

21, aromatic: (daily) essence 0.01%-0.1%；

22, skin conditioning agent: glycerol 1%-1.5%；Water 1%-2%；Hydrolyzed vegetable protein 0.00001-0.0005%；

23, skin conditioning agent: water 1%-2%；Pungent glycol 0.000001%-0.0001%；Acetyl group hexapeptide- 80.000001%-0.001%；

24, skin conditioning agent: glycerol 1%-1.5%；Water 1%-2%；- 5 0.000005%- of palmityl tripeptides 0.001%；

25, skin conditioning agent: glycerol 1%-1.5%；Water 1%-2%；Dipeptides diaminobutyryl benzyl amide diacetin 0.000005%-0.001%；

26, colorant: CI 191400.00005%-0.0005%；

27, colorant: CI 159850.00005%-0.0005%.

In some alternative embodiments, F phase can be only pH adjusting agent.

In an exemplary embodiment, by the percent by weight for preparing raw material, F phase includes following raw material:

28, pH adjusting agent: sodium hydroxide 0.05%-0.3%.

It should be understood that under normal conditions, E phase, F phase are added under conditions of 40-50 DEG C.

The emulsified particles partial size that product made from the preparation method of face cream is repaired in the application moisturizing is relatively large, but product Stability is still fine；And good using skin sense, ductility is good when smearing, with skin paste it is right it is high, absorb it is fast, without sticky sense, It is soft using rear skin softness.

The feature of the application and performance are described in further detail with reference to embodiments.

Embodiment 1

The present embodiment provides a kind of moisturizings to repair face cream, is made according to the following steps:

One, prepare raw material:

1, solvent: water 60kg；

2, moisturizer: glycerol 3kg；Maize germ extract 2kg；

3, moisturizer: butanediol 5kg；

4, skin conditioning agent: water 4kg；Lauroyl dilactic acid sodium 0.5kg；Phytosphingosine 0.1kg；Ceramide 30.1kg；Phenoxyethanol 0.1kg；Cer AP II 0.1kg；Cholesterine 0.1kg；Xanthan gum 0.05kg；Sensiva SC50 0.03kg；Carbomer 0.3kg；Cer EOS 0.00001kg；

5, preservative: Phenoxyethanol 0.1kg；

6, preservative: methyl hydroxybenzoate 0.2kg；EDETATE SODIUM 0.02kg；Sensiva SC50 0.1kg；

7, thickener: carbomer 0.3kg；

8, film forming agent: Sodium Polyacrylate 0.1kg；Water 1kg；

9, skin conditioning agent: Sodium Hyaluronate 0.05kg；

10, grease type emollient: ring five dimethyl silicone polymer 3kg；

11, emulsifier: the smooth tristearate 6kg of sorb；

12, grease type emollient: cetanol 2kg；

13, emulsifier: polyglycereol-3-methyl distearate 2kg；

14, grease type emollient: hydrogenated coco-glyceride class 1kg；

15, emollient: dimethyl silicone polymer 1kg；Dimethicone/Vinyl Dimethicone crosslinking is poly- Close object 0.1kg；

16, emollient: dimethyl silicone polymer 1kg；Dimethiconol 0.05kg；

17, moisturizer: -8/5/3 glycerol 3kg of PEG/PPG/ polytetramethylene glycol；Tocopherol (vitamin E) 0.02kg；

18, skin conditioning agent: water 1kg；Phenoxyethanol 0.03kg；Biological carbohydrate gum -10.05kg；

19, skin conditioning agent: glycerol 1kg；Water 1kg；Thallus laminariae extract 0.05kg；Sargassum fusifome alcohol extracting thing 0.05kg；

20, antioxidant: polyethylene glycol-8 0.05kg；Tocopherol 0.025kg；Ascorbyl palmitate 0.01kg；It is anti- Bad hematic acid (vitamin C) 0.0006kg；Citric acid 0.0006kg；

21, aromatic: (daily) essence 0.05kg；

22, skin conditioning agent: glycerol 1kg；Water 2kg；Hydrolyzed vegetable protein 0.0005kg；

23, skin conditioning agent: water 2kg；Pungent glycol 0.0001kg；Argireline 0.0001kg；

24, skin conditioning agent: glycerol 1kg；Water 2kg；Palmityl tripeptides -50.00001kg；

25, skin conditioning agent: glycerol 1.5kg；Water 2kg；Dipeptides diaminobutyryl benzyl amide diacetin 0.0001kg；

26, colorant: CI 191400.0002kg；

27, colorant: CI 159850.0002kg；

28, pH adjusting agent: sodium hydroxide 0.1kg.

Two, 1-6 raw material is uniformly mixed, A phase is made；7-9 raw material is uniformly mixed, B phase is made；By No. 10-14 Raw material is uniformly mixed, and C phase is made；15-16 raw material is uniformly mixed, D phase is made；17-27 raw material is uniformly mixed, is made E phase；No. 28 raw materials are uniformly mixed, F phase is made.

Three, B phase is added into A phase, dissolution obtains mixed phase, and F phase is then added, and forms gel phase.

Four, C phase is added into gel phase under the conditions of 75 DEG C, D phase is added after dissolution under agitation, is uniformly mixed E phase is added afterwards, and is uniformly mixed.

Five, 25 DEG C are cooled to；It is filtered using 100 mesh filter screens；Before Material discharging, Q.C. sampling carries out semi-finished product detection；Material After the assay was approved, filling, packed products carry out product inspection, qualification factory to body.

Embodiment 2

The present embodiment provides a kind of moisturizings to repair face cream, and preparation step is roughly the same with embodiment 1, and difference exists In the raw material that the present embodiment uses is as follows:

1, solvent: water 62kg；

2, moisturizer: glycerol 2kg；Maize germ extract 2kg

3, moisturizer: butanediol 8kg；

4, skin conditioning agent: water 4kg；Lauroyl dilactic acid sodium 0.3kg；Phytosphingosine 0.05kg；Ceramide 30.05kg；Phenoxyethanol 0.05kg；Cer AP II 0.05kg；Cholesterine 0.05kg；Xanthan gum 0.05kg；Ethylhexyl Glycerol 0.1kg；Carbomer 0.3kg；Cer EOS 0.00001kg；

5, preservative: Phenoxyethanol 0.01kg；

6, preservative: methyl hydroxybenzoate 0.1kg；EDETATE SODIUM 0.1kg；Sensiva SC50 0.2kg；

7, thickener: carbomer 0.4kg；

8, film forming agent: Sodium Polyacrylate 0.1kg；Water 1kg；

9, skin conditioning agent: Sodium Hyaluronate 0.1kg；

10, grease type emollient: ring five dimethyl silicone polymer 3kg；

11, emulsifier: the smooth tristearate 5kg of sorb；

12, grease type emollient: cetanol 1kg；

13, emulsifier: polyglycereol-3-methyl distearate 2kg；

14, grease type emollient: hydrogenated coco-glyceride class 1.5kg；

15, emollient: dimethyl silicone polymer 0.5kg；Dimethicone/Vinyl Dimethicone crosslinking Polymer 0.5kg；

16, emollient: dimethyl silicone polymer 0.5kg；Dimethiconol 0.05kg；

17, moisturizer: -8/5/3 glycerol 4kg of PEG/PPG/ polytetramethylene glycol；Tocopherol (vitamin E) 0.01kg；

18, skin conditioning agent: water 1.5kg；Phenoxyethanol 0.05kg；Biological carbohydrate gum -10.1kg；

19, skin conditioning agent: glycerol 1.5kg；Water 1kg；Thallus laminariae extract 0.1kg；Sargassum fusifome alcohol extracting thing 0.1kg

20, antioxidant: polyethylene glycol-8 0.02kg；Tocopherol 0.005kg；Ascorbyl palmitate 0.03kg；It is anti- Bad hematic acid (vitamin C) 0.0002kg；Citric acid 0.0005kg；

21, aromatic: (daily) essence 0.01kg；

22, skin conditioning agent: glycerol 1.5kg；Water 1kg；Hydrolyzed vegetable protein 0.0002kg；

23, skin conditioning agent: water 1kg；Pungent glycol 0.00005kg；Argireline 0.0005kg；

24, skin conditioning agent: glycerol 1.5kg；Water 1.5kg；Palmityl tripeptides -50.0006kg；

25, skin conditioning agent: glycerol 1kg；Water 1.5kg；Dipeptides diaminobutyryl benzyl amide diacetin 0.00005kg；

26, colorant: CI 191400.0001kg；

27, colorant: CI 159850.0001kg；

28, pH adjusting agent: sodium hydroxide 0.2kg.

Comparative example 1

This comparative example provides a kind of moisturizing reparation face cream, and preparation step is roughly the same with embodiment 1, and difference exists In this comparative example is not added with maize germ extract.

Comparative example 2

This comparative example provides a kind of moisturizing reparation face cream, and preparation step is roughly the same with embodiment 1, and difference exists In this comparative example is not added with biological carbohydrate gum -1.

Comparative example 3

This comparative example provides a kind of moisturizing reparation face cream, and preparation step is roughly the same with embodiment 1, and difference exists In this comparative example is not added with thallus laminariae extract.

Comparative example 4

This comparative example provides a kind of moisturizing reparation face cream, and preparation step is roughly the same with embodiment 1, and difference exists In this comparative example is not added with sargassum fusifome alcohol extracting thing.

Comparative example 5

This comparative example provides a kind of moisturizing reparation face cream, and preparation step is roughly the same with embodiment 1, and difference exists In this comparative example is not added with hydrolyzed vegetable protein.

The performance for repairing face cream to the moisturizing of the embodiment of the present application below by way of test detects.

One, quality detects

Test process:

The evaluation method of skin sense general impression: in April, 2019, on Hangzhou martial arts circles square, by the guarantor of embodiment and comparative example It is one week on probation that wet reparation face cream is supplied to randomly selected 30 volunteers (each 15 of men and women), and passes through social platform point Issue volunteer's electronic evaluating list.Evaluation is made for the following index of product respectively, according to 1-5 points of evaluations, quality detection is total Body impression average value=each index scoring × corresponding weight/weight summation, total assembly average；Evaluation criterion such as following table institute Show:

Salubrious degree；During spread product, the salubrious degree of skin is felt, it is higher to be more obvious score；

Moisture feeling；After smearing product absorption, feels skin and do not dry, do not tighten sense, there is plump sense, feel to get over Obvious score is higher；

Touch bullet sense；Product is being squeezed out and is being rubbed on hand the stage of wiping, and more bullet score is higher；

Degree of sprawling；Product uniformity in rubbing is more preferable, is not easy large stretch of attachment, effect is better to be more obvious.

Testing result is as shown in the table:

By upper Biao Ke get, the embodiment of the present application 1 and 2 product stability of embodiment are fine；And it is good using skin sense, when smearing Ductility is good, fastly with the right high, absorption of skin paste, without sticky sense.

In addition, product cut size made from embodiment 1 and embodiment 2 is relatively large, texture also increases compared with comparative example thin It is greasy.

Two, moistening effect detects

Test period: on 03 17th, 2019.

Test objective: to using moisture-keeping efficacy test evaluation in 8h after product.

Testee: 30.

Test method: choosing subject's forearm song side measurement region is 3 × 3cm², chosen at seven on both arms (for seven A experimental example), after cleaning, product is applied to region to be measured.Respectively using Corneometer (moisture of skin tester) In the measurement for carrying out cuticula moisture content in region to be measured before and using rear 0h, 2h, 4h and 8h.The same site measurement 5 times, 3 average value is taken to record after excluding maximum value and minimum value.

Subject is similarly 30 people.Volunteer is chosen from Beijing Technology and Business University's Foodstuffs Academy.

The tested time is season in late spring in March, 2019, and spring is since climate change is frequent, so the sensitive journey of human skin Spend larger, and period in late spring, skin condition tend towards stability again, so experiment effect confidence level is higher.

Test place: Beijing Technology and Business University's plant resources research and develop key lab.

Measuring device: Corneometer (CK, Germany).

Interpretation of result method: it is evaluated by Corneometer CM825 testing and analysis data.

Test result refers to table, and (data all take the average of 30 people, in addition, therein indicate coating using rear 0h On the skin after massaging after a period of time).

According to upper table it is found that after product made from the preparation method provided using the embodiment of the present application 1, cuticula moisture increases Long rate is 200%, and using rear 8h cuticula moisture growth rate, still there are also 99.2%%.It can be seen that production provided by the embodiments of the present application Product have immediately with 8h moistening effect.

In addition, the experimental data of embodiment 2 similarly illustrates have the effect of and embodiment 1.

Also, consolidated statement particular content it can be seen that, in comparative example, each effect for omitting component.

Especially it is worth mentioning that:

Comparative example 1, in lacked maize germ extract, so obvious insufficient in moisturizing effect, after can refer to use 0h and the data for using rear 4h, it is evident that compared to Examples 1 and 2, moisturizing effect and moistening effect are all poor.

Lack biological carbohydrate gum -1 in comparative example 2, although can find out the effect of moisturizing within 0h after use by data Upper and embodiment 1/2 is without too big gap, but in moisturizing, and there are a certain distance, especially after use 4h and When 4h, even if there are also certain moisturizing effects, but without enough moisture-keeping functions, so final effect is also poor.

Lack hydrolyzed vegetable protein in comparative example 5, also the same volume using effect bad, final due to moistening effect It is barely satisfactory.

Three, anti-aging/repairing effect detection

Case related data: choosing 80, skin relaxation is coarse, wrinkle is more, the experimenter more than epidermal pigment calmness, the age Between 30-55 years old.

Application method: after thorough clean skin, the Essence that embodiment 1 is prepared equably is smeared on skin, is gently clapped It beats, sooner or later respectively using once, every 28 days as a treatment course use 1~4 course for the treatment of.

Judgment criteria:

Effective: user feels very satisfied, and skin has elastic more consolidation children sliding, and skin exquisiteness is moist, skin Lasting water moistens soft and smooth gloss, and wrinkle significantly reduces；Dermatoglyph density significantly reduces under microscope, and skin color obviously shoals. Subject is without allergy or other toxicities.

Effective: user feels general satisfaction, and skin elasticity gloss lubricity increased；Wrinkle is reduced； Dermatoglyph density is reduced under microscope, and skin color shoals.

Invalid: user feels dissatisfied, and the coarse dry sensation of skin is not improved, and wrinkle is without reduction, skin bullet Property gloss lubricity is without increase；Dermatoglyph density is not improved under microscope, and epidermal pigment calmness is not improved.

Using effect

This 80 are recorded and paid a return visit, concrete outcome such as table 1:

During use, subject occurs without allergy or other toxicities.Total effective rate of the present invention reaches 96.25%, embodiment 2 also has same effect.

The result of comparative example 3 is as follows:

The result of comparative example 4 is as follows:

By above-mentioned test it is found that the present embodiment moisturizing reparation face cream respectively prepares raw material interaction, especially opotism Dish extract and sargassum fusifome alcohol extracting thing are indispensable, lack any one and prepare raw material all and can significantly affect product and repair to skin Multiple effect.

In conclusion the moisturizing reparation face cream of the embodiment of the present application is good to skin moisture-keeping, repairing effect, it is highly-safe, and It is low to prepare energy consumption.

The above description is only an example of the present application, the protection scope being not intended to limit this application, for ability For the technical staff in domain, various changes and changes are possible in this application.Within the spirit and principles of this application, made Any modification, equivalent substitution, improvement and etc. should be included within the scope of protection of this application.

Claims

1. face cream is repaired in a kind of moisturizing, which is characterized in that it prepares raw material and consists of the following compositions according to percent by weight:

2. face cream is repaired in moisturizing according to claim 1, which is characterized in that the ceramide includes:

Cer NP 0.005%-0.1%；

Cer AP II 0.005%-0.1%；And

Cer EOS 0.00001%-0.0001%.

3. face cream is repaired in moisturizing according to claim 1, which is characterized in that the anti-wrinkle ingredient includes:

Argireline 0.000001%-0.001%；

- 5 0.000005%-0.001% of palmityl tripeptides；

Dipeptides diaminobutyryl benzyl amide diacetin 0.000005%-0.001%.

4. face cream is repaired in moisturizing according to claim 1, which is characterized in that the emulsifier includes smooth three stearic acid of sorb At least one of ester, polyglycereol-3-methyl distearate；And/or the pH adjusting agent includes sodium hydroxide, lemon At least one of acid；And/or the antioxidant include tocopherol, ascorbyl palmitate, in ascorbic acid at least It is a kind of.

5. face cream is repaired in moisturizing according to claim 1, which is characterized in that the grease type emollient includes poly dimethyl Siloxanes, Dimethicone/Vinyl Dimethicone cross-linked polymer, dimethiconol, ring five are poly- At least one of dimethyl siloxane, cetanol, hydrogenated coco-glyceride class.

6. face cream is repaired in moisturizing according to claim 1, which is characterized in that the raw material for preparing further includes 1%-5%'s Second moisturizer；And/or described prepare the surfactant that raw material further includes 0.1%-0.5%；And/or described prepare raw material It further include the thickener of 0.5%-1%；And/or described prepare the film forming agent that raw material further includes 0.05%-0.3%.

7. face cream is repaired in moisturizing according to claim 1, which is characterized in that the raw material for preparing further includes 0.2%- 0.9% preservative, the preservative include Phenoxyethanol, methyl hydroxybenzoate, pungent glycol, at least one in Sensiva SC50 Kind.

8. face cream is repaired in moisturizing according to claim 1, which is characterized in that the raw material for preparing further includes 0.001%- 0.05% stabilizer, the stabilizer include xanthan gum.

9. face cream is repaired in moisturizing according to claim 1, which is characterized in that the raw material for preparing further includes 0.05%- 0.3% chelating agent；And/or described prepare the aromatic that raw material further includes 0.01%-0.1%；And/or described prepare raw material It further include the colorant of 0.0001%-0.001%.

10. the preparation method that face cream is repaired in a kind of moisturizing as described in claim 1, which is characterized in that itself the following steps are included:

By the butanediol, the phytosphingosine, the cholesterine, the ceramide and at least partly described glycerol, portion The water is divided to form the first water phase；

The second water phase that the Sodium Hyaluronate and remaining the part water are formed is added into first water phase, dissolves To mixed phase；

At least partly described pH adjusting agent is first added into the mixed phase, then adds the emulsifier and the part oil The dispersed phase oil phase that lipid emollient is formed, is added the remaining at least partly described grease type moisturizing under agitation after dissolution Dosage form at oily phase, be added after mixing it is remaining it is described prepare raw material, and be uniformly mixed.