CN108464958A - A kind of high osmosis cosmetic composition and preparation method thereof - Google Patents

A kind of high osmosis cosmetic composition and preparation method thereof Download PDF

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Publication number
CN108464958A
CN108464958A CN201810596302.8A CN201810596302A CN108464958A CN 108464958 A CN108464958 A CN 108464958A CN 201810596302 A CN201810596302 A CN 201810596302A CN 108464958 A CN108464958 A CN 108464958A
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CN
China
Prior art keywords
cosmetic composition
high osmosis
phase
emulsifier
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810596302.8A
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Chinese (zh)
Inventor
周生玉
刘瑞学
冷群英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Bawei Biological Technology Co Ltd
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Guangdong Bawei Biological Technology Co Ltd
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Priority to CN201810596302.8A priority Critical patent/CN108464958A/en
Publication of CN108464958A publication Critical patent/CN108464958A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant

Abstract

The invention discloses a kind of high osmosis cosmetic compositions and preparation method thereof, it is desirable to provide a kind of grain size is small, is easy to, by percutaneous absorption, have long-acting permanent moisturizing, prevents dry skin, rebuild the composition of sebum film;Its technical solution includes the component that following weight percentage is:Emulsifier phase 5 40%, oil phase 3 25%, surplus are water phase;It each component and its accounts for high osmosis cosmetic composition weight percent in the emulsifier phase and is:Emulsifier 1 8%, polyalcohol 3 20%, water 1 12%;Two (lauramide glutamine) Sodium lysinates are mainly contained in the emulsifier;Belong to cosmetic technical field.

Description

A kind of high osmosis cosmetic composition and preparation method thereof
Technical field
The invention discloses a kind of high osmosis cosmetic compositions, and the invention also discloses the high osmosis cosmetics groups The preparation method for closing object, belongs to cosmetic technical field.
Background technology
Cosmetics be mainly using object human body skin, the skin organ important as human body preventing body water Shunting is lost, outside contamination and stimulant invade and keep specious etc. and play a crucial role.It is mended to reach Water, water lock, firm skin and other effects, skin type cosmetic product typically contains water phase and oil phase, and water phase and oil phase are mutual not phases Two molten class I liquid Is need that emulsifier is added in grease system, and pass through one to form the system for being uniformly dispersed, stablizing Fixed emulsification method is emulsified.Skin-care cosmetics type on the market is various, but its formula and manufacture craft be not through Rise weigh, it appears that be all it is same production method is simply mixed, lack science, stability, the security risks of product are higher, Active constituent in cosmetics cannot be by percutaneous absorption, skin care inefficiency.
Therefore it needs to develop a kind of active constituent to be easy to by percutaneous absorption, safely and effectively cosmetics, to meet market Needs.
Invention content
The object of the present invention is to provide a kind of high osmosis cosmetic compositions, and the composition grain size is small, is easy to by skin The effect of absorbing, there is long-acting permanent moisturizing, prevent dry skin, rebuild sebum film.
For this purpose, first technical solution provided by the present application is such:
A kind of high osmosis cosmetic composition, including component that following weight percentage is:Emulsifier phase 5-40%, oil Phase 3-25%, appropriate water phase.
It each component and its accounts for high osmosis cosmetic composition weight percent in the emulsifier phase and is:Emulsifier 1- 8%, polyalcohol 3-20%, water 1-12%;
Two (lauramide glutamine) Sodium lysinates and PEG-40 hydrogenated castors are mainly contained in the emulsifier phase Oily, polynary alcohol and water.
Preferably, above-mentioned a kind of high osmosis cosmetic composition each component and its accounts for hypertonic in the emulsifier Permeability cosmetic composition weight percent is:Two (lauramide glutamine) Sodium lysinate 0.1-1%, PEG-40 hydrogenate castor Sesame oil 0.1-1%, PEG-100 stearate 0.5-3%, -6 0.3-3% of ceteareth.
Preferably, above-mentioned a kind of high osmosis cosmetic composition each component and its accounts for hypertonic in the polyalcohol Permeability cosmetic composition weight percent is:Butanediol 1-8%, dipropylene glycol 1-7%, glycerine 1-5%.
Preferably, above-mentioned a kind of high osmosis cosmetic composition key component and its accounts for Thief zone in the oil phase Property cosmetic composition weight percent is:Xingan raspberry seed oil 0.5-5%, wineberry seed oil 0.5-6%, print plus fruit seed Oily 2-6%.
Preferably, above-mentioned a kind of high osmosis cosmetic composition each component and its accounts for Thief zone in the water phase Property cosmetic composition weight percent is:Carambola leaf extract 0.5-6%, Fu Laixieshi willowweed extract 0.5-5%, it hangs down Basin grass extract 0.5-5%, appropriate amount of water.
Preferably, above-mentioned a kind of high osmosis cosmetic composition, the oil phase further include following components and its account for height Permeability cosmetic composition weight percent is:Cooked food Etard palm fibre fruit oil 0.5-4%, bitter oily seeds of trees oil 0.5-4%.
The latter solution of the present invention is to provide the preparation method of above-mentioned high osmosis cosmetic composition, this method For:
1) oil phase component is added in oil phase pot, is heated to 70 ± 3 DEG C, stirs evenly, it is spare;
2) each component of the water phase components 70 ± 3 DEG C are heated to be uniformly mixed, it is spare;
3) emulsifier, the polyalcohol in the emulsifier phase are added in emulsification pot, are heated to 70 ± 3 DEG C of stirring and dissolvings Completely, the water of emulsifier phase is then added, stirring is transparent, under agitation, is slowly added to the oil phase substance of step 1) preparation, It is eventually adding the aqueous phase substance of the preparation of step 2), is stirred evenly.
Compared with prior art, technical solution provided by the invention has following technological merit:
1, technical solution provided by the invention is (the lauramide glutamy of amino acid nonionic emulsifier two used Amine) Sodium lysinate, no HLB value dependence, safety is mild degradable, has unique twin-lock amphiphile, amphiphilic molecule structure:Plural number is hydrophobic Base and plural hydrophilic group combine, and form twin-lock structure, have high surface, to emulsification, solubilising and dispersibility Etc. a variety of advantageous characteristics, it can assign product excellent stability, core component double bond is combined with amido bond, and containing multiple Hydrophily tail, in conjunction with superior characteristic of solubilizing and emulsifiability PEG-40/PEG-40 rilanit specials.The technical program is prominent The coemulsifier emulsified using Cremophor RH40 as generation twin-lock amino acid microemulsified and D phases of broken property uses, In compound botanical extract, there is good compatibility with skin, reticular structure can be formed and be leniently wrapped in skin, refigure It is rich in flexibility the tender skin with elasticity, and mentions protection skin barrier function.
2, technical solution provided by the invention can be good at discharging and absorbing Xingan's raspberry seed oil, wineberry (VACCINIUM MYRTILLUS) seed oil, print plus the necessary aliphatic acid in fruit (PLUKENETIA VOLUBILIS) seed oil, insatiable hunger With aliphatic acid and vitamin, more nutrition are provided for skin, to be obviously improved skin histology binding force, are releived and flesh living of waking up Skin, help improves skin, and protects the effect of skin is from free radical damage, moisturizing of moistening, and skin is made to restore water profit vigor, Moisture-retaining capacity is improved, maintenance sebum film can strengthen skin phylactic power defensive power, enhance skin barrier, to protect skin from extraneous ring Border is damaged.
3, technical solution provided by the invention is synergistic, reasonable formula, compounding carambola (AVERRHOA CARAMBOLA) Leaf extract, Fu Laixieshi willowweeds (EPILOBIUM FLEISCHERI) extract and Herba Sedi extract can increase promotion and be closed The expression of albumen and transglutaminase locks skin moisture, prevents dry skin coarse, enables skin water profit fine and smooth, maintains year Light health status.
4, technical solution provided by the invention is also rich in amino acid, grease, anthocyanidin, flavones ingredient, with good Whitening is releived antiallergy effect.
Specific implementation mode
With reference to embodiment, the claim of the present invention is described in further detail.
Embodiment 1
A kind of high osmosis cosmetic composition provided by the invention, each component and its content are as follows:
Embodiment 2
A kind of high osmosis cosmetic composition provided by the invention, each component and its content are as follows:
Embodiment 3
A kind of high osmosis cosmetic composition provided by the invention, each component and its content are as follows:
Embodiment 4
A kind of high osmosis cosmetic composition provided by the invention, each component and its content are as follows:
Embodiment 5
A kind of high osmosis cosmetic composition provided by the invention, each component and its content are as follows:
The preparation method of the embodiment of the present invention 1 to embodiment 5 is:
1) oil phase component is added in oil phase pot, is heated to 70 ± 3 DEG C, stirs evenly, it is spare;
2) each component of the water phase components 70 ± 3 DEG C are heated to be uniformly mixed, it is spare;
3) emulsifier, the polyalcohol in the emulsifier phase are added in emulsification pot, are heated to 70 ± 3 DEG C of stirring and dissolvings Completely, the water of emulsifier phase is then added, stirring is transparent, under agitation, is slowly added to the oil phase substance of step 1) preparation, It is eventually adding the aqueous phase substance of the preparation of step 2), is stirred evenly.
The high osmosis cosmetic composition of the present invention is added to by the conventional method of cosmetic field in cosmetics, can It is added in toner, lotion, face cream, facial mask, essence, face cleaning product, additive amount 3-35%.
In order to better illustrate advantages of the present invention, the application method and work(of technical solution provided by the present application is given below Imitate test experience.
Experimental example 1
Skin closure type patch test
Tested material is high osmosis cosmetic composition of the embodiment of the present invention 1 to embodiment 5.Subject is skin health 100 volunteers, be divided into 5 groups, every group 20.
Test method is tested material to be put into spot examination device, dosage is about 0.020g~0.025g, will be added with tested material Spot examination device is pasted on back or the forearm song side of subject with non-stimulated adhesive tape, is gently pressed with palm and is allowed to equably be pasted on skin On, continue for 24 hours.Remove tested material after 24 hours, 0.5,24 hour after removing patch, 48 hours, observation skin it is anti- It answers, according to《Cosmetics health specification》Dermoreaction grade scale record in (2007 editions) is as a result, standard of perfection is shown in Table 1, experiment It the results are shown in Table 2.
1 standard of perfection of table
Grade Standard of perfection
0 It is non-stimulated, without erythema
1 Slight erythema
2 Erythema
3 Erythema, papule, bubble
4 Serious attached edema, bulla
2 patch test results of table
From table 2 it can be seen that the high osmosis cosmetic composition of the embodiment of the present invention 1 to embodiment 5 does not have human body Cause any allergy or discomfort, illustrates that the high osmosis cosmetic composition of the present invention is safe, non-stimulated.
Experimental example 2
Moisture-keeping efficacy is tested
The moisture that human skin keratinocyte's layer is measured using capacitance method is the D-value of dielectric constant based on water He other substances Different notable, according to the difference of keratoderma moisture, the capacitance of the skin measured is different, and parameter can represent skin water Divide content.
Sample:The high osmosis cosmetic composition of embodiment 1 to 5 is added in emulsion matrix, forms lotion 1 to breast The additive amount of liquid 5, high osmosis cosmetic composition is 20%.Control group is emulsion matrix.
The trier for selecting 60 20-40 Sui is randomly divided into 6 groups, every group 10.Trier uses lotion 1 to lotion respectively 5, emulsion matrix continues 30 days respectively using once sooner or later daily.
At the 0th day and the 30th day moisture content of skin, assessment were detected with moisture content of skin tester Corneometer CM825 Use the water content situation of skin before and after lotion.Moisture-keeping efficacy test result is shown in Table 3.
3 moisture content of skin situation of change of table
0th day moisture 30th day moisture Moisture growth rate (%)
Lotion 1 30.28 38.75 27.98
Lotion 2 31.89 38.61 21.07
Lotion 3 30.47 37.89 24.35
Lotion 4 32.56 37.09 20.57
Lotion 5 30.97 36.99 19.43
Control 31.56 31.66 0.32
It is added using the high osmosis cosmetic composition of the embodiment of the present invention 1 to 5 it can be seen from 3 experimental result of table To lotion made from emulsion matrix, skin moisture content can be significantly improved, illustrates the high osmosis cosmetics group using the present invention It closes object and has good moisture-keeping efficacy.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment Limitation, it is other it is any without departing from the spirit and principles of the present invention made by changes, modifications, substitutions, combinations, simplifications, Equivalent substitute mode is should be, is included within the scope of the present invention.

Claims (7)

1. a kind of high osmosis cosmetic composition, which is characterized in that the component for being including following weight percentage:Emulsifier phase 5-40%, oil phase 3-25%, surplus are water phase
It each component and its accounts for high osmosis cosmetic composition weight percent in the emulsifier phase and is:Emulsifier 1-8%, Polyalcohol 3-20%, water 1-12%;
Two (lauramide glutamine) Sodium lysinates and Cremophor RH40 are mainly contained in the emulsifier.
2. a kind of high osmosis cosmetic composition according to claim 1, which is characterized in that each in the emulsifier It component and its accounts for high osmosis cosmetic composition weight percent and is:Two (lauramide glutamine) Sodium lysinate 0.1- 1%, Cremophor RH40 0.1-1%, PEG-100 stearate 0.5-3%, -6 0.3-3% of ceteareth.
3. a kind of high osmosis cosmetic composition according to claim 1, which is characterized in that each in the polyalcohol It component and its accounts for high osmosis cosmetic composition weight percent and is:Butanediol 1-8%, dipropylene glycol 1-7%, glycerine 1- 5%.
4. a kind of high osmosis cosmetic composition according to claim 1, which is characterized in that main group in the oil phase Divide and its account for high osmosis cosmetic composition weight percent and is:Xingan raspberry seed oil 0.5-5%, wineberry seed oil 0.5-6%, print plus fruit seed oil 2-6%.
5. a kind of high osmosis cosmetic composition according to claim 1, which is characterized in that each group in the water phase Divide and its account for high osmosis cosmetic composition weight percent and is:Carambola leaf extract 0.5-6%, Fu Laixieshi willowweed carries Take object 0.5-5%, Herba Sedi extract 0.5-5%, appropriate amount of water.
6. a kind of high osmosis cosmetic composition according to claim 4, which is characterized in that further include in the oil phase It following components and its accounts for high osmosis cosmetic composition weight percent and is:Cooked food Etard palm fibre fruit oil 0.5-4%, the bitter oily seeds of trees Oily 0.5-4%.
7. the preparation method of high osmosis cosmetic combinations described in claim 1, which is characterized in that
1) oil phase component is added in oil phase pot, is heated to 70 ± 3 DEG C, stirs evenly, it is spare;
2) each component of the water phase components 70 ± 3 DEG C are heated to be uniformly mixed, it is spare;
3) emulsifier, the polyalcohol in the emulsifier phase are added in emulsification pot, it is complete is heated to 70 ± 3 DEG C of stirring and dissolvings Entirely, the water of emulsifier phase is then added, stirring is transparent, under agitation, is slowly added to the oil phase substance of step 1) preparation, most The aqueous phase substance of the preparation of step 2) is added afterwards, stirs evenly.
CN201810596302.8A 2018-06-11 2018-06-11 A kind of high osmosis cosmetic composition and preparation method thereof Pending CN108464958A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110075007A (en) * 2019-06-06 2019-08-02 广州微肽生物科技有限公司 With waterproof, the oil-in-water sunscreen product for improving skin elasticity and preparation method thereof
CN110269812A (en) * 2019-03-19 2019-09-24 广州市拉凯尔干细胞研究所 A kind of raw material of skin care articles preparation method containing ubiquinone
CN111053728A (en) * 2020-01-15 2020-04-24 广州极男化妆品有限公司 Composition for regulating water-oil balance of skin and cosmetic thereof

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CN107898671A (en) * 2017-12-19 2018-04-13 广州汇川医药科技有限公司 A kind of alligator oil restorative facial cream and preparation method thereof
CN107929175A (en) * 2018-01-03 2018-04-20 中山市天图精细化工有限公司 A kind of gentle makeup removing mousse and preparation method thereof

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CN105228585A (en) * 2013-05-16 2016-01-06 帝斯曼知识产权资产管理有限公司 Topical compositions
CN107744481A (en) * 2017-10-26 2018-03-02 广州市禾基生物科技有限公司 A kind of moisturizing releive spraying and preparation method thereof
CN107898671A (en) * 2017-12-19 2018-04-13 广州汇川医药科技有限公司 A kind of alligator oil restorative facial cream and preparation method thereof
CN107929175A (en) * 2018-01-03 2018-04-20 中山市天图精细化工有限公司 A kind of gentle makeup removing mousse and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110269812A (en) * 2019-03-19 2019-09-24 广州市拉凯尔干细胞研究所 A kind of raw material of skin care articles preparation method containing ubiquinone
CN110075007A (en) * 2019-06-06 2019-08-02 广州微肽生物科技有限公司 With waterproof, the oil-in-water sunscreen product for improving skin elasticity and preparation method thereof
CN110075007B (en) * 2019-06-06 2022-03-22 广州微肽生物科技有限公司 Oil-in-water sunscreen product with waterproof and skin elasticity improving functions and preparation method thereof
CN111053728A (en) * 2020-01-15 2020-04-24 广州极男化妆品有限公司 Composition for regulating water-oil balance of skin and cosmetic thereof

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