CN107496194A - A kind of surfactant and preparation method thereof - Google Patents
A kind of surfactant and preparation method thereof Download PDFInfo
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- CN107496194A CN107496194A CN201610414681.5A CN201610414681A CN107496194A CN 107496194 A CN107496194 A CN 107496194A CN 201610414681 A CN201610414681 A CN 201610414681A CN 107496194 A CN107496194 A CN 107496194A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The present invention relates to cosmetic field, and in particular to a kind of surfactant and preparation method thereof.The surfactant contains Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, Sodium Hyaluronate.It is characteristic of the invention that the cosmetic composition is using the composition of a variety of natural origins as main active component；Can timely moisturizing, the long-acting moisturizing of and can, make skin present water profit state；Cellular respiration can be promoted simultaneously, lift cell consumption rate, promote cell metabolism, reduce oxidative stress；And free radical and active oxygen can be effectively removed, impaired skin is repaired, reaches the effect of protecting skin.Each component reasonable combination, synergy is safe and stable, can be used for moisturizing, in the cosmetics that energy is provided for skin.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of surfactant and preparation method thereof.
Background technology
With advancing age, the turnover rate of human keratinous layer becomes slower and slower, while the lipid synthesis of horn cell
Ability declines, or cell division, growth and differentiation efficiency step-down in epidermis.Because skin lacks moisturizing factor and lipid, angle
Matter layer barrier function declines increasingly.When cuticula moisture is less than 10%, skin, which will seem, to be dried, follows the string, rising
Wrinkle, and then accelerate skin aging.On the other hand, improperly life style it is for example excessive wash one's face or have a bath and bad environment because
Element can also make cuticula such as the air or pollutant and intrinsic disease such as allergy (atopy) or senile skin disease dried
Lose the function of its script.Skin is encroached on by sweltering heat, cold, wind, cleaning agent and ultraviolet radiation etc., and top layer can become more
Add drying.Water is the important composition composition of skin, and the high skin of water content, epidermal cell metabolism is normal, and epidermis energy fills
Foot, show tender, plentiful, glossy and soft outward appearance.For example infant's skin is seemed delicate light due to its water content higher position
Pool, and old application on human skin is because water content is relatively low, seem and dry and flat, the easy furfur that withers, wrinkle even occurs.Cause
How this, keep the moisture of skin, and it is particularly significant in cosmetics research and development to reduce moisture loss.
In addition, with age, the secretion of the hormone of the various regulation metabolism of human body skin itself is reduced, and is immunized thin
The function and activity decrease of born of the same parents, this reduces the synthesis of the immune protein and structural proteins that cause to form live body.Form skin
Collagen, elastin laminin, hyaluronic acid and the content of glycoprotein and arrangement (arrangement) change or reduced, and due to
Free radical and active oxygen and oxidative stress occurs.Reach the amount of earth surface ultraviolet increases due to the destruction of ozone layer, and
It is on the rise with environmental pollution, free radical and active oxygen increase.Thinning of skin, wrinkle increase, skin elasticity declines, the colour of skin
Become obscure, various skin problems frequently occur.Therefore, in cosmetics design, in addition to moisturizing, it is also contemplated that removing certainly
By base and active oxygen, and how to promote cellular respiration.
At present, in the market has that the cosmetics of moisture-keeping efficacy are very more, and is not solely restricted to top layer moisturizing, vertical
Body, deep layer, maintenance, long-acting aspect propose " 4D moisturizings ", " 6D moisturizings " concept, and develop more efficient natural moisturizings
Agent.Although these measures can timely moisturizing, strengthen the water lock of skin, water storage, water delivery barrier function, be the failure to fundamentally change
Become the dry sensation of skin.Secondly, also there is the product for declaring " multi-efficiency " in the market, and freedom can be removed while moisturizing
Base, there is anti-oxidation efficacy, but actual research effect shows that they only possess the effect of simple superposition mostly, not
Have to multiple skin problems and be obviously improved effect.
The content of the invention
In order to solve the above-mentioned technical problem, first purpose of the invention is to provide a kind of surfactant, and the surfactant can
In timely moisturizing, can timely moisturizing, the long-acting moisturizing of and can, make skin that water profit state be presented；Cellular respiration can be promoted simultaneously, carried
Cell consumption rate is risen, promotes cell metabolism, reduces oxidative stress；And free radical and active oxygen can be effectively removed, is repaired
Impaired skin, reaches the effect of protecting skin.Second object of the present invention is to provide a kind of preparation side of above-mentioned surfactant
Method.
In order to realize first above-mentioned purpose, present invention employs following technical scheme：
A kind of surfactant, by mass percentage the surfactant include following component：
Margarita extract 0.01 ~ 20%
Saccharomycete lysis thing extract 0.01 ~ 10%
Fructus psidii guajavae immaturus extract 0.01 ~ 20%
Sodium Hyaluronate 0.001 ~ 1%；
Surplus is that surfactant often uses matrix and water.
Preferably, the surfactant includes following component by mass percentage：
Margarita extract 0. 1 ~ 10%
Saccharomycete lysis thing extract 0.05 ~ 5%
Fructus psidii guajavae immaturus extract 0.1 ~ 10%
Sodium Hyaluronate 0.01 ~ 0.2%；
Surplus is that surfactant often uses matrix and water.
As further preferably, the surfactant includes following component by mass percentage：
Margarita extract 0. 5 ~ 5%
Saccharomycete lysis thing extract 0.1 ~ 5%
Fructus psidii guajavae immaturus extract 0.5 ~ 5%
Sodium Hyaluronate 0.02 ~ 0.15%；
Surplus is that surfactant often uses matrix and water.
Preferably, surfactant is often made up of with matrix following component by mass percentage：
NMF 1 ~ 20%
Chelating agent 0.01 ~ 1%
Thickener 0 ~ 1%
Preservative qs.
As further preferably, surfactant is often made up of with matrix following component by mass percentage：
NMF 2 ~ 10%
Chelating agent 0.01 ~ 0.1%
Thickener 0 ~ 0.5%
Preservative qs.
Margarita extract in surfactant of the present invention is on the basis of super-fine pearl powder powder, by biological enzymolysis technique, instead
Phase high pressure liquid phase separation techniques, the polypeptide for possessing active function being obtained, its content of peptides is between 1.0-20.0mg/ml, admittedly contain
Amount is between 2.0-20.0%.Moisturizing water lock not only is played in skin surface, more from basalis maintenance cellular environment, promotes collagen
The secretion of the water lock composition such as albumen, play deep layer multiple-effect moisture-keeping function.
Saccharomycete lysis thing extract of the present invention is yeast cells in controlled ambient pressure（As necessarily
Dose ultraviolet line irradiates）Caused metabolite under condition of culture, got through breaking-wall cell extraction, also known as yeast living cells spreads out
Biology（Live Cell Yeast Derivatives, abbreviation LYCD）.This typical eukaryotic of yeast is pressed when by the external world
The reaction that power is made when stimulating has many similarities with mankind fibroblast, and this is the active ingredient in cosmetics
Using providing theoretical foundation.
Yeast lysis thing extract is by the material composition of the low relative molecular masses such as amino acid, glycopeptide, nucleotides, and this is carried
Thing active matter content is taken between 25%-40%.The extract can increase new in Skin Cell as a kind of peculiar NMF
The absorption of raw albumen confrontation moisture, promote utilization of the skin to oxygen, so that skin is plentiful.The extract also has promotion transparent
Matter acid synthesis, promotes the synthesis of elastin laminin and collagen, suppresses free radical, increase cell aerobic respiration, releive, promote wound
Healing and other effects.Human test shows that the extract can strengthen skin moisture-keeping, strengthens skin tightness, improves skin UV damages
Wound, energy is refilled for skin, allow skin to keep fit state.
Guava in surfactant of the present invention is tropical fruit tree, is evergreen dungarunga or shrub, be commonly called as pulling out guava, that
Pull out.Because it is from foreign countries, therefore named is guava, is one of subtropical zone famous and high-quality fruit kind.Fruit has treatment diabetes and drop
The drug effect of blood glucose, blade can also control diarrhoea.Fruit can also be processed into fruit juice, inspissated juice, fruit powder, jam, concentration in addition to eating raw
Slurry, jelly etc..Alphalin, B, E, and two kinds strong effective polyphenoils --- Punica granatum L. polyphenol and anthocyanidin are rich in guava,
Free radical can be effectively neutralized, is enhanced metabolism, effectively helps skin discharge " toxin ".
Sodium Hyaluronate in surfactant of the present invention, is a kind of macromolecule NMF of natural origin, its molecular weight distribution
In 1.0*105Da and 3.0*106Between Da, purity is more than 90%.Layer protecting film can be formed in skin surface, protect flesh
Skin, strengthen skin barrier function.
NMF in surfactant of the present invention includes but is not limited to glycerine, and propane diols, 1,3-PD, butanediol, oneself two
Alcohol, 1,2- pentanediol, pungent glycol and combinations thereof.
Chelating agent in surfactant of the present invention includes but is not limited to EDTA disodiums, the sodium of EDTA tetra-, phytic acid, sodium phytate and its
Composition.
Thickener in surfactant of the present invention includes but is not limited to ammonium acryloyldime-thyltaurate/VP copolymers, xanthan
Glue, Sodium Polyacrylate, acrylic acid（Ester）Analog copolymer sodium, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, gather
Acrylate -13, the ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25, acrylic acid
Hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers and combinations thereof.
In order to realize second above-mentioned purpose, present invention employs following technical scheme：
A kind of preparation method of above-mentioned surfactant, this method comprise the following steps：
1）Surfactant is often added in reaction pot with matrix and water and Sodium Hyaluronate, stirring is opened, is heated to 75 ~ 80 DEG C,
It is uniformly dispersed；
2）Cooling circulating water is opened, stirring cooling, when temperature is down to 40 ~ 45 DEG C, Margarita extract, saccharomycete lysis thing are extracted
Thing, Fructus psidii guajavae immaturus extract and preservative are added in reaction pot, and stirring and dissolving is complete；
3）Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
The present invention not only plays moisturizing water lock as a result of above-mentioned technical scheme, Margarita extract in skin surface,
More from basalis maintenance cellular environment, promote the secretion of the water lock compositions such as collagen, play deep layer multiple-effect moisture-keeping function.It is and saturating
Bright matter acid sodium, layer protecting film mainly is formed in skin surface, strengthen skin barrier function, pin moisture.Yeast lysis thing carries
Take thing that skin can be promoted to synthesize hyaluronic acid, elastin laminin and collagen, absorption of the increase skin to moisture, while can press down
Free radical processed, increase cell aerobic respiration, lift cell consumption rate, promote cell metabolism, reduce oxidative stress.Can be effective
Free radical is neutralized, is enhanced metabolism.The compounding of several active components of the present invention, is not merely moisturizing or benefit in traditional sense
Water effect, but while moisturizing moisturizing, maintenance is damaged skin, understands free radical in skin, provides energy for skin, makes flesh
The restorative water profit state of skin.
Brief description of the drawings
Fig. 1 be surfactant use before, the keratoderma change of moisture content rate figure of 4 hours after 1 hour and use after use.
Fig. 2 is volunteer's wrinkle depth analysis chart.
Embodiment
Surfactant provided by the invention be with Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, thoroughly
Bright matter acid sodium is main component, be aided with cosmetics often with matrix components for example NMF, thickener, preservative, chelating agent, essence with
And water is made.A part of specific embodiment is set forth below, and the present invention will be described, but is not intended to limit present disclosure.
Embodiment 1
Form surfactant component and its relative content be：
The preparation method of above-mentioned surfactant, comprises the following steps：Water, glycerine, Sodium Hyaluronate and xanthans are added into reaction pot
In, stirring is opened, 75 ~ 80 DEG C is heated to, is uniformly dispersed；Cooling circulating water is opened, stirring cools, when temperature is down to 40 ~ 45 DEG C,
Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract and preservative are added in reaction pot, stirring and dissolving is complete
Entirely；Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
Embodiment 2
Form surfactant component and its relative content be：
The preparation method of above-mentioned surfactant, comprises the following steps：By water, propane diols, the sodium of EDTA tetra-, Sodium Hyaluronate and propylene
Acyl dimethyltaurine ammonium/VP copolymers are added in reaction pot, are opened stirring, are heated to 75 ~ 80 DEG C, are uniformly dispersed；Open cooling
Recirculated water, stirring cooling, when temperature is down to 40 ~ 45 DEG C, by Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus
Extract and preservative are added in reaction pot, and stirring and dissolving is complete；Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring,
Terminate.
Embodiment 3
Form surfactant component and its relative content be：
The preparation method of above-mentioned surfactant, comprises the following steps：By water, 1,3- propane diols, 1,2- pentanediols, phytic acid, hyalomitome
Sour sodium is added in reaction pot, is opened stirring, is heated to 75 ~ 80 DEG C, is uniformly dispersed；Cooling circulating water is opened, stirring cooling, treats temperature
When being down to 40 ~ 45 DEG C, Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract and preservative are added and reacted
In pot, stirring and dissolving is complete；Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
Embodiment 4
Form surfactant component and its relative content be：
The preparation method of above-mentioned surfactant, comprises the following steps：By water, butanediol, EDETATE SODIUM, Sodium Hyaluronate and xanthans
Add in reaction pot, open stirring, be heated to 75 ~ 80 DEG C, be uniformly dispersed；Cooling circulating water is opened, stirring cooling, treats that temperature is down to
At 40 ~ 45 DEG C, Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract and preservative are added in reaction pot,
Stirring and dissolving is complete；Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
Embodiment 5
Form surfactant component and its relative content be：
The preparation method of above-mentioned surfactant, comprises the following steps：By water, 1,3- propane diols, EDETATE SODIUM, Sodium Hyaluronate and Huang
Virgin rubber is added in reaction pot, is opened stirring, is heated to 75 ~ 80 DEG C, is uniformly dispersed；Cooling circulating water is opened, stirring cooling, treats temperature
When being down to 40 ~ 45 DEG C, Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract and preservative are added and reacted
In pot, stirring and dissolving is complete；Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
The moisture-keeping efficacy of embodiment 6 is evaluated
The surfactant provided in this experimental selection embodiment 4 carries out clinical trial.
The experiment includes 22 volunteers, and the age is in 21-45 one full year of life.Tested material and data are used according to regulations during experiment
It is complete.It is unified to clean both hands inner forearm before experiment, carry out measurement markers.Product smear zone and blank district random distribution
Region is demarcated in left and right arm, it is ensured that all product and white space positions statistically reach balance.First measure each region
Initial value, then test sample is pressed into ormal weight single application.In setting time point product is carried out using moisture of skin tester
Region and the measurement of control zone, each region parallel determination 5 times, record of averaging.
According to formula keratoderma change of moisture content rate=[（Th-T0）- (Th blank-T0 blank)]/T0, calculate skin care
Before water use, the keratoderma change of moisture content rate of 4 hours after 1 hour and use after use, see Fig. 1.As a result show, skin care
Water makes keratoderma water content after 1h have to improve a lot, and can preferably be tieed up within 4 hours after use
Hold.
The instant anti-wrinkle effect assessment of embodiment 7
The surfactant provided in this experimental selection embodiment 4 carries out clinical trial.
The experiment includes 5 volunteers, and the age is in 25-45 one full year of life.Appropriate surfactant is taken to be applied at eye microgroove.Use hand
Refer to finger pulp and flick eye to sample all absorptions.With imported from America VISIA-CR professional skins image analysis system to eye skin
Skin wrinkle index using it is preceding and using 30 minutes after analyzed.After having used surfactant 30 minutes, wrinkle depth ratio uses
Before reduce 10%, see a certain position volunteer wrinkle depth analysis charts of Fig. 2.Ridge part represents skin bulge part, mountain in Fig. 2
Ridge part is more, represents that wrinkle of skin is fewer.
Claims (10)
1. a kind of surfactant, it is characterised in that the surfactant includes following component by mass percentage：
Margarita extract 0.01 ~ 20%
Saccharomycete lysis thing extract 0.01 ~ 10%
Fructus psidii guajavae immaturus extract 0.01 ~ 20%
Sodium Hyaluronate 0.001 ~ 1%；
Surplus is that surfactant often uses matrix and water.
2. a kind of surfactant according to claim 1, it is characterised in that the surfactant includes following by mass percentage
Component：
Margarita extract 0. 1 ~ 10%
Saccharomycete lysis thing extract 0.05 ~ 5%
Fructus psidii guajavae immaturus extract 0.1 ~ 10%
Sodium Hyaluronate 0.01 ~ 0.2%；
Surplus is that surfactant often uses matrix and water.
3. a kind of surfactant according to claim 1, it is characterised in that the surfactant includes following by mass percentage
Component：
Margarita extract 0. 5 ~ 5%
Saccharomycete lysis thing extract 0.1 ~ 5%
Fructus psidii guajavae immaturus extract 0.5 ~ 5%
Sodium Hyaluronate 0.02 ~ 0.15%；
Surplus is that surfactant often uses matrix and water.
4. according to a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that by mass percentage
Meter surfactant is often made up of with matrix following component：
Glycerine 1 ~ 20%
Xanthans 0.01 ~ 0.5%
EDETATE SODIUM 0.01 ~ 0.1%
Preservative qs.
5. according to a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that by mass percentage
Meter surfactant is often made up of with matrix following component：
Glycerine 1 ~ 10%
Xanthans 0.05 ~ 0.2%
EDETATE SODIUM 0.01 ~ 0.05%
Preservative qs.
6. according to a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that Margarita extract is
The a variety of peptides and the mixture of amino acid that pearl powder obtains through enzymolysis；Content of peptides is in 1.0-20.0mg/ in Margarita extract
Between ml, solid content is between 2.0-20.0%.
7. according to a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that female bacterium lysis thing carries
Thing is taken, is yeast cells caused metabolite under controlled ambient pressure condition of culture, is got through breaking-wall cell extraction,
By including amino acid, glycopeptide, the material composition of nucleotides and other low relative molecular masses, the extract non-volatile content
Between 25%-40%.
8. according to a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that Fructus psidii guajavae immaturus extract
Thing solid content is in 1%-2%.
9. according to a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that Sodium Hyaluronate point
Son amount is distributed in 1.0*105Da and 3.0*106Between Da, purity is more than 90%.
10. the method that one kind prepares a kind of surfactant described in claim 1 ~ 3 any one claim, it is characterised in that should
Method comprises the following steps：
1）Surfactant is often added in reaction pot with matrix and water and Sodium Hyaluronate, stirring is opened, is heated to 75 ~ 80 DEG C,
It is uniformly dispersed；
2）Cooling circulating water is opened, stirring cooling, when temperature is down to 40 ~ 45 DEG C, Margarita extract, saccharomycete lysis thing are extracted
Thing, Fructus psidii guajavae immaturus extract and preservative are added in reaction pot, and stirring and dissolving is complete；
3）Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
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| CN201610414681.5A CN107496194A (en) | 2016-06-13 | 2016-06-13 | A kind of surfactant and preparation method thereof |
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| CN201610414681.5A CN107496194A (en) | 2016-06-13 | 2016-06-13 | A kind of surfactant and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108042473A (en) * | 2017-12-27 | 2018-05-18 | 广西还珠海洋生物科技有限公司 | A kind of surfactant containing pearl |
| CN109363974A (en) * | 2018-12-04 | 2019-02-22 | 福建植护网络科技有限公司 | A kind of moisturiser and preparation method thereof |
| CN110755362A (en) * | 2019-11-06 | 2020-02-07 | 广州远想生物科技有限公司 | A skin caring composition containing yeast cell extract |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105078873A (en) * | 2014-05-16 | 2015-11-25 | 天津强微特生物科技有限公司 | Biological skin protecting composition with tightening and whitening effects |
| CN105434312A (en) * | 2015-12-30 | 2016-03-30 | 天津嘉氏堂科技有限公司 | Psidium guajava moisturizing toner |
-
2016
- 2016-06-13 CN CN201610414681.5A patent/CN107496194A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105078873A (en) * | 2014-05-16 | 2015-11-25 | 天津强微特生物科技有限公司 | Biological skin protecting composition with tightening and whitening effects |
| CN105434312A (en) * | 2015-12-30 | 2016-03-30 | 天津嘉氏堂科技有限公司 | Psidium guajava moisturizing toner |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108042473A (en) * | 2017-12-27 | 2018-05-18 | 广西还珠海洋生物科技有限公司 | A kind of surfactant containing pearl |
| CN109363974A (en) * | 2018-12-04 | 2019-02-22 | 福建植护网络科技有限公司 | A kind of moisturiser and preparation method thereof |
| CN110755362A (en) * | 2019-11-06 | 2020-02-07 | 广州远想生物科技有限公司 | A skin caring composition containing yeast cell extract |
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Application publication date: 20171222 |