CN104042545A - Age-reducing skin care product aiming at cell gene regeneration and repair - Google Patents

Age-reducing skin care product aiming at cell gene regeneration and repair Download PDF

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CN104042545A
CN104042545A CN201410255382.2A CN201410255382A CN104042545A CN 104042545 A CN104042545 A CN 104042545A CN 201410255382 A CN201410255382 A CN 201410255382A CN 104042545 A CN104042545 A CN 104042545A
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CN104042545B (en
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刘佰岭
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Guangzhou Zhongfu Biotechnology Co ltd
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Abstract

The invention relates to an age-reducing skin care product aiming at cell gene regeneration and repair. The age-reducing skin care product consists of the following raw materials in percentage by weight: 8-20 percent of human placenta extract, 4-10 percent of magnesium ascorbyl phosphate, 1-3 percent of acetyl hexapeptide-8, 1-3 percent of palmitoyl oligopeptide, 1-3 percent of palmitoyl tetrapeptide-3, 1-3 percent of tocopherol, 0.05-2 percent of eryngium maritimum extract, 0.05-3 percent of sodium hyaluronate, 3-5 percent of xanthan gum, 0.30 percent of bi(hydroxymethyl) imidazolidinyl urea, 0.20 percent of allantoin, 0.10 percent of EDTA tetrasodium, 0.03 percent of sodium pyrosulfite, 11.00 percent of butanediol and the balance of deionized water. Polypeptide tightening factors of a proper ratio such as acetyl hexapeptide-8, palmitoyl oligopeptide and palmitoyl tetrapeptide-3 are adopted and are combined with the human placenta extract and eryngium maritimum extract, and the product has the effects of tightening the skin, increasing the skin elasticity, preventing wrinkles and delaying skin aging.

Description

A kind ofly subtract skin-protection product in age for cytogene Regeneration and Repair
Technical field
The present invention relates to a kind of for cytogene Regeneration and Repair subtract skin-protection product in age and preparation method thereof, belong to skin care field.
Background technology
Human skin is aging is the skin aging phenomenon being caused by natural cause or non-natural cause.After people is born, skin histology is day by day flourishing, and function is active gradually, will start to degenerate when certain age of arrival, and this degeneration is often slowly carried out unconsciously people.The growth stage of skin histology generally ended at about 25 years old, from after this growth with agingly carry out simultaneously, Elastic fibers is chap gradually, 25~28 old phases of the beginning of the year, skin aging slowly obvious, although degree of aging can vary with each individual.
Skin aging is conventionally embodied in skin elasticity, wrinkle of skin and roughness, moistens the several respects such as intensity.Use moisturizer skin protection simple in daily life is obviously inadequate for prevention skin aging.The factors such as environment, sunlight and pressure can make free radical injure greatly skin, impel skin ageing to accelerate.At this time skin also easily goes out a little speckles, and the phenomenons such as microgroove, so need to be used the skin care item of the crease-resistant raising skin elasticity of antioxidation.
Time causes health aging, and skin metabolism slows down, the collagen protein of skin and elastic fiber degeneration.Therefore need to use the skin-protection product of Rosemary Extract to slow down the aging of skin, for example, can select some to generate the skin care item of repairing for cytogene by stimulation collagen.
Summary of the invention
Technical problem to be solved by this invention be to provide a kind of for cytogene Regeneration and Repair subtract skin-protection product in age, for the skin and crease-resistant that compacts, improve skin moisturizing intensity, improve wrinkle of skin and roughness, increase skin elasticity.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind ofly subtract skin-protection product in age for cytogene Regeneration and Repair, raw material by following weight percent content forms: human placental extract 8~20%, magnesium L-ascorbyl-2-phosphate 4~10%, Argireline 1~3%, palmitoyl oligopeptide 1~3%, Palmitoyl Tetrapeptide-31~3% tocopherol 1~3%, the perverse celery extract 0.05~2% in strand, sodium hyaluronate 0.05-3%, xanthan gum 3-5%, diazolidinyl urea 0.30%, allantoin 0.20%, EDTA tetra-sodium 0.10%, sodium pyrosulfite 0.03%, butanediol 11.00%, surplus is deionized water.
The invention has the beneficial effects as follows: owing to having adopted the polypeptide of the proper proportion factor (acetyl group six peptide~8, palmitoyl oligopeptide, Palmitoyl Tetrapeptide~3) of compacting, have the following advantages in conjunction with human placental extract, the strand high-efficiency activated synergism of perverse celery extract:
1, improve the adaptive capacity of skin to environment, even if skin, in the most nervous environment, still keeps young expression;
2, promote the synthetic collagen protein of skin self, the quantity of collagen fiber and elastic fiber is increased, make skin present full and elasticity from inside to outside;
3, excite the generation of collagen protein, elastin laminin and basic substance, fundamentally reduce wrinkle with lax;
4, filling corium lacks and maintains the structural integrity of skin corium, makes the rapid consolidation of skin, flexible;
5, promote the regeneration of cell, strengthen resisting microgroove and smooth cut generation, allow skin recapture consolidation.
On the basis of technique scheme, the present invention can also do following improvement.
Preferably; described skin care item are made up of the raw material of following weight percent content: human placental extract 10~15%; magnesium L-ascorbyl-2-phosphate 5~8%; Argireline 2%; palmitoyl oligopeptide 2%; Palmitoyl Tetrapeptide-32%, tocopherol 2%, the perverse celery extract 1.5% in strand; sodium hyaluronate 1.5%; xanthan gum 4%, diazolidinyl urea 0.30%, allantoin 0.20%; EDTA tetra-sodium 0.10%; sodium pyrosulfite 0.03%, butanediol 11.00%, surplus is deionized water.
The present invention also provides a kind of preparation method that subtracts skin-protection product in age for cytogene Regeneration and Repair, comprises the following steps:
Step (1): take deionized water (AQUA), butanediol (BUTYLENE GLYCOL), xanthan gum (XANTHAN GUM), hyaluronate sodium (SODIUM HYALURONATE), allantoin (ALLANTOIN) as A phase by the percentage by weight of above-mentioned skin care item, take human placental extract (HUMAN PLACENTAL EXTRACT), magnesium L-ascorbyl-2-phosphate (MAGNESIUM ASCORBYL PHOSPHATE), Argireline (ACETYL HEXAPEPTIDE-8), palmitoyl oligopeptide (PALMITOYL OLIGOPEPTIDE), Palmitoyl Tetrapeptide-3 (PALMITOYL TETRAPEPTIDE-3), tocopherol (vitamin E) (TOCOPHEROL), the perverse celery extract in strand (ERYNGIUM MARITIMUM EXTRACT) is as B, take diazolidinyl urea (DIAZOLIDINYL UREA), EDTA tetra-sodium (TETRASODIUM EDTA) as C phase,
A is dropped into mutually 78~80 DEG C of agitated kettle agitating heating by step (2), dissolves completely, is incubated cooling after 20 minutes; B is expected to add the A item of 35~40 DEG C of lowering the temperature mutually, and mix and blend 10~15 minutes completely evenly; Finally add C to stir mutually; Filter, discharging, leaves standstill; Fill after the assay was approved, packaging, product inspection warehousing after passing.
Primary raw material of the present invention has following effect:
Human placental extract: crease-resistant, skin tightening effect.The erythrocyte factor and female sex hormone in Placenta extract can make old and feeble skin regeneration, have effect of defying age, wrinkle resistance, whitening.
1, the effect to speckle.When the superfluous generation of melanin, remain on skin always, will become speckle.Human placental extract can regulate melanic excessive and not enough phenomenon, and prefabricated melanic generation promotes melanin excretion, effectively prevents and improves speckle, reaches the object of light speckle, molten speckle, speckle dispelling.Except speckle, also effective in cure for atopic dermatitis and facial cicatrix.
2, to partially black, dark yellow effect.In human placental extract, the multiple precious composition such as contained several amino acids, polypeptide, protein, nucleic acid can improve skin nutrition, promotes horn cell division, accelerates skin tissue's metabolism, pins nutrient, can long-acting whitening, and desalination mottle.
3, prevent skin aging.The antioxidant such as human placental extract's rich in vitamin E, inject life to old and feeble cell, prevent that cell from being encroached on by oxygen-derived free radicals, the cell having damaged are carried out to repair simultaneously, make the women who likes to be beautiful dynamic, give youth and beauty for change.In Placenta Hominis, contain the necessary various nutritional labelings of Skin Cell, and accelerate a large amount of productions of protein, fat, actin, elastin laminin and the glue protein of Skin Cell, delay, subdue wrinkle and various aging phenomenon.
The perverse celery in strand (Chinese: Hai Dongqing) extract: be the powerful anti-oxidation characteristics of active component, can directly act on epidermis-corium context layer and skin corium, the free radical producing under all ambient pressures of perfect antagonism and oxidation infringement.
The polypeptide factor (acetyl group six peptide~8, palmitoyl oligopeptide, Palmitoyl Tetrapeptide~3) of compacting: by stimulating layer to be adhered albumen (LamininV) IV; VII collagen type makes skin consolidation; can promote the generation of collagen protein and other extracellular matrix proteins (comprising elastin laminin and fibronectin etc.); promote the water content of skin; increase tight skin solidity and reduce microgroove; improvement face and near the eyes aging vestige; skin reappears full consolidation, young moist.
Magnesium L-ascorbyl-2-phosphate: can effectively resist ultraviolet invasion and attack, and can catch oxygen-derived free radicals, promote collagen protein to generate, can effectively prevent and treat pigmentation, dispel various skin splashs, can make skin moisturizing, delicate, bright and clean and this product stable, nontoxic, non-stimulated.
Tocopherol (vitamin E): one of antioxidant.Effectively reduce the generation of wrinkle, the appearance retaining youth.Protection skin is avoided the injury of ultraviolet and pollution, reduces the deposition of cicatrix and pigment.In the time being seeped into skin bottom, can be converted into active antioxidant, can resist free radical and protect skin to avoid external environment condition infringement.
Sodium hyaluronate: transparent human body natural moisture preserving composition, moisturizing lastingly, promotes the absorption of other active component, for dermal collagen and elastic fiber synthetic provides good environment, alleviates aging wrinkle vestige.
The present invention chooses research that above-mentioned raw materials carries out proper proportion and obtains effective synergism and reach the skin that compacts, wrinkle removing, increase skin elasticity, the effect of moistening intensity that improves, allow 40 years old skin, when recovering 23 years old young skin quality, can ensure that obtained skin care item have popular acceptable excellent flavor and good stability.
In sum; the invention provides a kind of crease-resistant, antioxidation of being made in conjunction with antioxidation, antiallergic, whitening, moisturizing and anticorrosion material combination by acetyl group six peptide~8, palmitoyl oligopeptide, Palmitoyl Tetrapeptide~3 and human placental extract, the perverse celery extract in strand, whitening, Moisturizer for increasing skin elasticity, improve wrinkle of skin, improve skin moisturizing intensity and there is synergism; can Rosemary Extract, slowing down skin aging; and skin care item product appearance, inherent quality that the present invention produces can maintain a long-term stability.
Detailed description of the invention
Below in conjunction with embodiment, principle of the present invention and feature are described, example, only for explaining the present invention, is not intended to limit scope of the present invention.
The human placental extract that the human placental extract Shanghai Zi Bang Chemical Co., Ltd. that following examples adopt produces; The perverse celery extract in described strand is the perverse celery extract in strand that Guangzhou Bai Haobo company limited produces, and Chinese is that east, sea is blue or green.
Embodiment 1
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind ofly subtract skin-protection product in age for cytogene Regeneration and Repair, raw material by following weight percent content forms: human placental extract 8g, magnesium L-ascorbyl-2-phosphate 10g, Argireline 3g, palmitoyl oligopeptide 1g, Palmitoyl Tetrapeptide-33g, tocopherol 3g, strand perverse celery extract 2g, sodium hyaluronate 3g, xanthan gum 3g, diazolidinyl urea 0.30g, allantoin 0.20g, EDTA tetra-sodium 0.10g, sodium pyrosulfite 0.03g, butanediol 11.00g, surplus is deionized water.
Above-mentioned a kind of preparation method that subtracts skin-protection product in age for cytogene Regeneration and Repair,, comprise the following steps:
Step (1): take deionized water (AQUA), butanediol (BUTYLENE GLYCOL), xanthan gum (XANTHAN GUM), hyaluronate sodium (SODIUM HYALURONATE), allantoin (ALLANTOIN) as A phase by the weight of the raw material of above-mentioned skin care item, take human placental extract (HUMAN PLACENTAL EXTRACT), magnesium L-ascorbyl-2-phosphate (MAGNESIUM ASCORBYL PHOSPHATE), Argireline (ACETYL HEXAPEPTIDE-8), palmitoyl oligopeptide (PALMITOYL OLIGOPEPTIDE), Palmitoyl Tetrapeptide-3 (PALMITOYL TETRAPEPTIDE-3), tocopherol (vitamin E) (TOCOPHEROL), the perverse celery extract in strand (ERYNGIUM MARITIMUM EXTRACT) is as B, take diazolidinyl urea (DIAZOLIDINYL UREA), EDTA tetra-sodium (TETRASODIUM EDTA) as C phase,
A is dropped into mutually 78~80 DEG C of agitated kettle agitating heating by step (2), dissolves completely, is incubated cooling after 20 minutes; B is expected to add the A phase of 35~40 DEG C of lowering the temperature mutually, and mix and blend 10~15 minutes completely evenly; Finally add C to stir mutually; Filter, discharging, leaves standstill; Fill after the assay was approved, packaging, product inspection warehousing after passing.
Skin care item prepared by embodiment 1 carry out dermatology clinical trial for 20 women and find after 4 weeks; 24% wrinkles on one's forehead reduce, and 27% temporal wrinkle reduces, and 19.5% tight skin solidity improves.Experimenter found after 4 weeks in addition: smoothing immediately microgroove has 90%, and reducing face's microgroove has 85%, and skin increases the degree of packing 90%, obviously felt that face's microgroove minimizing has 85%.
Embodiment 2
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind ofly subtract skin-protection product in age for cytogene Regeneration and Repair, raw material by following weight percent content forms: human placental extract 15g, magnesium L-ascorbyl-2-phosphate 8g, Argireline 2g, palmitoyl oligopeptide 2g, Palmitoyl Tetrapeptide-32g, tocopherol 2g, strand perverse celery extract 1.5g, sodium hyaluronate 1.5g, xanthan gum 4g, diazolidinyl urea 0.30g, allantoin 0.20g, EDTA tetra-sodium 0.10g, sodium pyrosulfite 0.03g, butanediol 11.00g, surplus is deionized water.
Above-mentioned a kind of preparation method that subtracts skin-protection product in age for cytogene Regeneration and Repair,, comprise the following steps:
Step (1): take water (AQUA), butanediol (BUTYLENE GLYCOL), xanthan gum (XANTHAN GUM), hyaluronate sodium (SODIUM HYALURONATE), allantoin (ALLANTOIN) as A phase by the percentage by weight of above-mentioned skin care item, take human placental extract (HUMAN PLACENTAL EXTRACT), magnesium L-ascorbyl-2-phosphate (MAGNESIUM ASCORBYL PHOSPHATE), Argireline (ACETYL HEXAPEPTIDE-8), palmitoyl oligopeptide (PALMITOYL OLIGOPEPTIDE), Palmitoyl Tetrapeptide-3 (PALMITOYL TETRAPEPTIDE-3), tocopherol (vitamin E) (TOCOPHEROL), the perverse celery extract in strand (ERYNGIUM MARITIMUM EXTRACT) is as B, take diazolidinyl urea (DIAZOLIDINYL UREA), EDTA tetra-sodium (TETRASODIUM EDTA) as C phase,
A is dropped into mutually 78~80 DEG C of agitated kettle agitating heating by step (2), dissolves completely, is incubated cooling after 20 minutes; B is expected to add the A phase of 35~40 DEG C of lowering the temperature mutually, and mix and blend 10~15 minutes completely evenly; Finally add C to stir mutually; Filter, discharging, leaves standstill; Fill after the assay was approved, packaging, product inspection warehousing after passing.
Skin care item prepared by embodiment 2 carry out dermatology clinical trial for 20 women and find after 4 weeks; 25% wrinkles on one's forehead reduce, and 28% temporal wrinkle reduces, and 22% skin consolidation improves.Experimenter found after 4 weeks in addition: smoothing immediately microgroove has 95%, and reducing face's microgroove has 90%, and skin increases the degree of packing 92%, obviously felt that face's microgroove minimizing has 80%.
Embodiment 3
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind ofly subtract skin-protection product in age for cytogene Regeneration and Repair, raw material by following weight percent content forms: human placental extract 20g, magnesium L-ascorbyl-2-phosphate 10g, Argireline 3g, palmitoyl oligopeptide 3g, Palmitoyl Tetrapeptide-31g, tocopherol 1g, strand perverse celery extract 0.05g, sodium hyaluronate 3g, xanthan gum 5g, diazolidinyl urea 0.30g, allantoin 0.20g, EDTA tetra-sodium 0.10g, sodium pyrosulfite 0.03g, butanediol 11.00g, surplus is deionized water.
Above-mentioned a kind of preparation method that subtracts skin-protection product in age for cytogene Regeneration and Repair,, comprise the following steps:
Step (1): take water (AQUA), butanediol (BUTYLENE GLYCOL), xanthan gum (XANTHAN GUM), hyaluronate sodium (SODIUM HYALURONATE), allantoin (ALLANTOIN) as A phase by the weight of the raw material of above-mentioned skin care item, take human placental extract (HUMAN PLACENTAL EXTRACT), magnesium L-ascorbyl-2-phosphate (MAGNESIUM ASCORBYL PHOSPHATE), Argireline (ACETYL HEXAPEPTIDE-8), palmitoyl oligopeptide (PALMITOYL OLIGOPEPTIDE), Palmitoyl Tetrapeptide-3 (PALMITOYL TETRAPEPTIDE-3), tocopherol (vitamin E) (TOCOPHEROL), the perverse celery extract in strand (ERYNGIUM MARITIMUM EXTRACT) is as B, take diazolidinyl urea (DIAZOLIDINYL UREA), EDTA tetra-sodium (TETRASODIUM EDTA) as C phase,
A is dropped into mutually 78~80 DEG C of agitated kettle agitating heating by step (2), dissolves completely, is incubated cooling after 20 minutes; B is expected to add the A phase of 35~40 DEG C of lowering the temperature mutually, and mix and blend 10~15 minutes completely evenly; Finally add C to stir mutually; Filter, discharging, leaves standstill; Fill after the assay was approved, packaging, product inspection warehousing after passing.
Skin care item prepared by embodiment 3 carry out dermatology clinical trial for 20 women and find after 4 weeks; 25% wrinkles on one's forehead reduce, and 26% temporal wrinkle reduces, and 20.5% skin consolidation improves.Experimenter found after 4 weeks in addition: smoothing immediately microgroove has 90%, and reducing face's microgroove has 86%, and skin increases the degree of packing 91%, obviously felt that face's microgroove minimizing has 87%.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (3)

1. one kind subtracts skin-protection product in age for cytogene Regeneration and Repair, it is characterized in that, raw material by following weight percent content forms: human placental extract 8~20%, magnesium L-ascorbyl-2-phosphate 4~10%, Argireline 1~3%, palmitoyl oligopeptide 1~3%, Palmitoyl Tetrapeptide-31~3%, tocopherol 1~3%, the perverse celery extract 0.05~2% in strand, sodium hyaluronate 0.05~3%, xanthan gum 3~5%, diazolidinyl urea 0.30%, allantoin 0.20%, EDTA tetra-sodium 0.10%, sodium pyrosulfite 0.03%, butanediol 11.00%, surplus is deionized water.
2. a kind ofly according to claim 1 subtract skin-protection product in age for cytogene Regeneration and Repair, it is characterized in that, raw material by following weight percent content forms: human placental extract 10~15%, magnesium L-ascorbyl-2-phosphate 5~8%, Argireline 2%, palmitoyl oligopeptide 2%, Palmitoyl Tetrapeptide-32% tocopherol 2%, the perverse celery extract 1.5% in strand, sodium hyaluronate 1.5%, xanthan gum 4%, diazolidinyl urea 0.30%, allantoin 0.20%, EDTA tetra-sodium 0.10%, sodium pyrosulfite 0.03%, butanediol 11.00%, surplus is deionized water.
3. an a kind of preparation method that subtracts skin-protection product in age for cytogene Regeneration and Repair described in claim 1, is characterized in that, comprises the following steps:
Step (1): take deionized water, butanediol, xanthan gum, hyaluronate sodium, allantoin as A phase by the middle percentage by weight of claim 1; Take human placental extract, magnesium L-ascorbyl-2-phosphate, Argireline, palmitoyl oligopeptide, Palmitoyl Tetrapeptide-3, tocopherol (vitamin E), the perverse celery extract in strand as B; Take diazolidinyl urea, EDTA tetra-sodium as C phase;
A is dropped into mutually 78~80 DEG C of agitated kettle agitating heating by step (2), dissolves completely, is incubated cooling after 20 minutes; B is expected to add the A item of 35~40 DEG C of lowering the temperature mutually, and mix and blend 10~15 minutes completely evenly; Finally add C to stir mutually; Filter, discharging, leaves standstill; Fill after the assay was approved, packaging, product inspection warehousing after passing.
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CN105943484A (en) * 2016-06-19 2016-09-21 原巍俊 Essence for after-sun repair and cell regeneration promotion
CN106176521A (en) * 2016-07-29 2016-12-07 赵冰丽 A kind of facial mask essence increasing skin elasticity and preparation method
CN106176488A (en) * 2016-08-31 2016-12-07 广东芭薇生物科技股份有限公司 A kind of whitening spot-eliminating composition regulating human body inflammatory reaction balance and application thereof
CN106473993A (en) * 2016-12-10 2017-03-08 珍尔姿(广州)化妆品有限公司 A kind of nourishing essence dew with crease-resistant effect
CN107308020A (en) * 2017-07-06 2017-11-03 珠海联邦制药股份有限公司 A kind of peptide composition of stabilization and its application
CN107693779A (en) * 2017-05-10 2018-02-16 广州润虹医药科技股份有限公司 One kind is dispelled scar composition and preparation method thereof
CN108524378A (en) * 2018-07-09 2018-09-14 福建省海乐威生物工程有限公司 A kind of anti-wrinkle cream of the ingredient containing jasmine and preparation method thereof
CN111110578A (en) * 2020-02-26 2020-05-08 唐爱梅 Anti-wrinkle essence with anti-wrinkle and anti-aging effects
CN111544324A (en) * 2020-06-05 2020-08-18 广东梵蜜琳生物科技有限公司 Composition and cosmetic for improving skin elasticity
CN113545999A (en) * 2020-04-23 2021-10-26 玫琳凯有限公司 Topical cosmetic composition
CN115417843A (en) * 2022-07-27 2022-12-02 深圳凯联健康生物科技有限公司 Compound or composition and application thereof in preparation of product with skin collagen production promoting effect
CN118161435A (en) * 2024-02-26 2024-06-11 华泽睿孚生物技术(广州)有限公司 Wrinkle removing and resisting composition containing coastal cress tissue culture

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CN105943484A (en) * 2016-06-19 2016-09-21 原巍俊 Essence for after-sun repair and cell regeneration promotion
CN106176521A (en) * 2016-07-29 2016-12-07 赵冰丽 A kind of facial mask essence increasing skin elasticity and preparation method
CN106176488A (en) * 2016-08-31 2016-12-07 广东芭薇生物科技股份有限公司 A kind of whitening spot-eliminating composition regulating human body inflammatory reaction balance and application thereof
CN106473993A (en) * 2016-12-10 2017-03-08 珍尔姿(广州)化妆品有限公司 A kind of nourishing essence dew with crease-resistant effect
CN107693779A (en) * 2017-05-10 2018-02-16 广州润虹医药科技股份有限公司 One kind is dispelled scar composition and preparation method thereof
CN107308020A (en) * 2017-07-06 2017-11-03 珠海联邦制药股份有限公司 A kind of peptide composition of stabilization and its application
CN108524378A (en) * 2018-07-09 2018-09-14 福建省海乐威生物工程有限公司 A kind of anti-wrinkle cream of the ingredient containing jasmine and preparation method thereof
CN111110578A (en) * 2020-02-26 2020-05-08 唐爱梅 Anti-wrinkle essence with anti-wrinkle and anti-aging effects
CN113545999A (en) * 2020-04-23 2021-10-26 玫琳凯有限公司 Topical cosmetic composition
CN111544324A (en) * 2020-06-05 2020-08-18 广东梵蜜琳生物科技有限公司 Composition and cosmetic for improving skin elasticity
CN111544324B (en) * 2020-06-05 2022-09-02 广东梵蜜琳生物科技有限公司 Composition and cosmetic for improving skin elasticity
CN115417843A (en) * 2022-07-27 2022-12-02 深圳凯联健康生物科技有限公司 Compound or composition and application thereof in preparation of product with skin collagen production promoting effect
CN118161435A (en) * 2024-02-26 2024-06-11 华泽睿孚生物技术(广州)有限公司 Wrinkle removing and resisting composition containing coastal cress tissue culture
CN118161435B (en) * 2024-02-26 2024-08-23 华泽睿孚生物技术(广州)有限公司 Wrinkle removing and resisting composition containing coastal cress tissue culture

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