CN107496310A - A kind of facial treatment essence liquid and preparation method thereof - Google Patents
A kind of facial treatment essence liquid and preparation method thereof Download PDFInfo
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- CN107496310A CN107496310A CN201610410565.6A CN201610410565A CN107496310A CN 107496310 A CN107496310 A CN 107496310A CN 201610410565 A CN201610410565 A CN 201610410565A CN 107496310 A CN107496310 A CN 107496310A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The present invention relates to cosmetic field, and in particular to a kind of facial treatment essence liquid and preparation method thereof.The facial treatment essence liquid contains Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, Sodium Hyaluronate.It is characteristic of the invention that the cosmetic composition is using the composition of a variety of natural origins as main active component;Can timely moisturizing, the long-acting moisturizing of and can, make skin present water profit state;Cellular respiration can be promoted simultaneously, lift cell consumption rate, promote cell metabolism, reduce oxidative stress;And free radical and active oxygen can be effectively removed, impaired skin is repaired, reaches the effect of protecting skin.Each component reasonable combination, synergy is safe and stable, can be used for moisturizing, in the cosmetics that energy is provided for skin.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of facial treatment essence liquid and preparation method thereof.
Background technology
With advancing age, the turnover rate of human keratinous layer becomes slower and slower, while the lipid synthesis of horn cell
Ability declines, or cell division, growth and differentiation efficiency step-down in epidermis.Because skin lacks moisturizing factor and lipid, angle
Matter layer barrier function declines increasingly.When cuticula moisture is less than 10%, skin, which will seem, to be dried, follows the string, rising
Wrinkle, and then accelerate skin aging.On the other hand, improperly life style it is for example excessive wash one's face or have a bath and bad environment because
Element can also make cuticula such as the air or pollutant and intrinsic disease such as allergy (atopy) or senile skin disease dried
Lose the function of its script.Skin is encroached on by sweltering heat, cold, wind, cleaning agent and ultraviolet radiation etc., and top layer can become more
Add drying.Water is the important composition composition of skin, and the high skin of water content, epidermal cell metabolism is normal, and epidermis energy fills
Foot, show tender, plentiful, glossy and soft outward appearance.For example infant's skin is seemed delicate light due to its water content higher position
Pool, and old application on human skin is because water content is relatively low, seem and dry and flat, the easy furfur that withers, wrinkle even occurs.Cause
How this, keep the moisture of skin, and it is particularly significant in cosmetics research and development to reduce moisture loss.
In addition, with age, the secretion of the hormone of the various regulation metabolism of human body skin itself is reduced, and is immunized thin
The function and activity decrease of born of the same parents, this reduces the synthesis of the immune protein and structural proteins that cause to form live body.Form skin
Collagen, elastin laminin, hyaluronic acid and the content of glycoprotein and arrangement (arrangement) change or reduced, and due to
Free radical and active oxygen and oxidative stress occurs.Reach the amount of earth surface ultraviolet increases due to the destruction of ozone layer, and
It is on the rise with environmental pollution, free radical and active oxygen increase.Thinning of skin, wrinkle increase, skin elasticity declines, the colour of skin
Become obscure, various skin problems frequently occur.Therefore, in cosmetics design, in addition to moisturizing, it is also contemplated that removing certainly
By base and active oxygen, and how to promote cellular respiration.
At present, in the market has that the cosmetics of moisture-keeping efficacy are very more, and is not solely restricted to top layer moisturizing, vertical
Body, deep layer, maintenance, long-acting aspect propose " 4D moisturizings ", " 6D moisturizings " concept, and develop more efficient natural moisturizings
Agent.Although these measures can timely moisturizing, strengthen the water lock of skin, water storage, water delivery barrier function, be the failure to fundamentally change
Become the dry sensation of skin.Secondly, also there is the product for declaring " multi-efficiency " in the market, and freedom can be removed while moisturizing
Base, there is anti-oxidation efficacy, but actual research effect shows that they only possess the effect of simple superposition mostly, not
Have to multiple skin problems and be obviously improved effect.
The content of the invention
In order to solve the above-mentioned technical problem, first purpose of the invention is to provide a kind of facial treatment essence liquid, skin care essence
Magnificent liquid can in timely moisturizing, can timely moisturizing, the long-acting moisturizing of and can, make skin present water profit state;It can promote simultaneously thin
Born of the same parents breathe, and lift cell consumption rate, promote cell metabolism, reduce oxidative stress;And it can effectively remove free radical and work
Property oxygen, repair impaired skin, the effect of reaching protection skin.Second object of the present invention is to provide a kind of above-mentioned skin care essence
The preparation method of magnificent liquid.
In order to realize first above-mentioned purpose, present invention employs following technical scheme:
A kind of facial treatment essence liquid, by mass percentage the facial treatment essence liquid include following component:
Margarita extract 0.01 ~ 20%
Saccharomycete lysis thing extract 0.01 ~ 10%
Fructus psidii guajavae immaturus extract 0.01 ~ 20%
Sodium Hyaluronate 0.001 ~ 1%;
Surplus is that facial treatment essence liquid often uses matrix and water.
Preferably, the facial treatment essence liquid includes following component by mass percentage:
Margarita extract 0. 1 ~ 10%
Saccharomycete lysis thing extract 0.05 ~ 5%
Fructus psidii guajavae immaturus extract 0.1 ~ 10%
Sodium Hyaluronate 0.01 ~ 0.2%;
Surplus is that facial treatment essence liquid often uses matrix and water.
As further preferably, the facial treatment essence liquid includes following component by mass percentage:
Margarita extract 0. 5 ~ 5%
Saccharomycete lysis thing extract 0.1 ~ 5%
Fructus psidii guajavae immaturus extract 0.5 ~ 5%
Sodium Hyaluronate 0.02 ~ 0.15%;
Surplus is that facial treatment essence liquid often uses matrix and water.
Preferably, facial treatment essence liquid is often made up of with matrix following component by mass percentage:
NMF 1 ~ 20%
Thickener 0.05 ~ 2%
Essence 0.03 ~ 1%
Preservative qs.
As further preferably, facial treatment essence liquid is often made up of with matrix following component by mass percentage:
NMF 1 ~ 20%
Thickener 0.1 ~ 1%
Essence 0.05 ~ 0.4%
Preservative qs.
Margarita extract in facial treatment essence liquid of the present invention is on the basis of super-fine pearl powder powder, passes through biological enzymolysis work
Skill, reversed phase high-pressure liquid phase separation techniques, obtain and possess the polypeptide of active function, its content of peptides between 1.0-20.0mg/ml,
Solid content is between 2.0-20.0%.Moisturizing water lock not only is played in skin surface, more from basalis maintenance cellular environment, is promoted
The secretion of the water lock composition such as collagen, play deep layer multiple-effect moisture-keeping function.
Saccharomycete lysis thing extract of the present invention is yeast cells in controlled ambient pressure(As necessarily
Dose ultraviolet line irradiates)Caused metabolite under condition of culture, got through breaking-wall cell extraction, also known as yeast living cells spreads out
Biology(Live Cell Yeast Derivatives, abbreviation LYCD).This typical eukaryotic of yeast is pressed when by the external world
The reaction that power is made when stimulating has many similarities with mankind fibroblast, and this is the active ingredient in cosmetics
Using providing theoretical foundation.
Yeast lysis thing extract is by the material composition of the low relative molecular masses such as amino acid, glycopeptide, nucleotides, and this is carried
Thing active matter content is taken between 25%-40%.The extract can increase new in Skin Cell as a kind of peculiar NMF
The absorption of raw albumen confrontation moisture, promote utilization of the skin to oxygen, so that skin is plentiful.The extract also has promotion transparent
Matter acid synthesis, promotes the synthesis of elastin laminin and collagen, suppresses free radical, increase cell aerobic respiration, releive, promote wound
Healing and other effects.Human test shows that the extract can strengthen skin moisture-keeping, strengthens skin tightness, improves skin UV damages
Wound, energy is refilled for skin, allow skin to keep fit state.
Guava in facial treatment essence liquid of the present invention is tropical fruit tree, is evergreen dungarunga or shrub, is commonly called as pulling out guava
Son, that pulls out.Because it is from foreign countries, therefore named is guava, is one of subtropical zone famous and high-quality fruit kind.Fruit has treatment diabetes
And hypoglycemic drug effect, blade can also control diarrhoea.Fruit can also be processed into fruit juice, inspissated juice, fruit powder, jam, dense in addition to eating raw
Contract slurry, jelly etc..Rich in Alphalin, B, E, and two kinds strong effective polyphenoils --- Punica granatum L. polyphenol and cyanine in guava
Element, free radical can be effectively neutralized, is enhanced metabolism, effectively help skin discharge " toxin ".
Sodium Hyaluronate in facial treatment essence liquid of the present invention, is a kind of macromolecule NMF of natural origin, its molecular weight
It is distributed in 1.0*105Da and 3.0*106Between Da, purity is more than 90%.Layer protecting film, protection can be formed in skin surface
Skin, strengthen skin barrier function.
NMF in facial treatment milk of the present invention includes but is not limited to glycerine, propane diols, 1,3-PD, butanediol, oneself
Glycol, 1,2- pentanediol, pungent glycol and combinations thereof.
Chelating agent in facial treatment milk of the present invention includes but is not limited to EDTA disodiums, the sodium of EDTA tetra-, phytic acid, sodium phytate and
Its composition.
Thickener in facial treatment milk of the present invention includes but is not limited to ammonium acryloyldime-thyltaurate/VP copolymers, gathers
PAA, acrylic acid(Ester)Analog copolymer sodium, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, polypropylene
Acid esters -13, the ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25, acrylic acid hydroxyl second
Ester/sodium acryloyldimethyl taurate copolymers and combinations thereof.
In order to realize second above-mentioned purpose, present invention employs following technical scheme:
A kind of preparation method of above-mentioned facial treatment essence liquid, this method comprise the following steps:
1)Water, NMF, thickener and Sodium Hyaluronate are added in reaction pot, stirring is opened, is heated to 75 ~ 80 DEG C, is disperseed
Uniformly;
2)Cooling circulating water is opened, stirring cooling, when temperature is down to 40 ~ 45 DEG C, adds Margarita extract, saccharomycete lysis thing carries
Thing, Fructus psidii guajavae immaturus extract, essence and preservative is taken to add in reaction pot, homogeneous 1 minute, stirring and dissolving is complete;
3)Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
The present invention not only plays moisturizing water lock as a result of above-mentioned technical scheme, Margarita extract in skin surface,
More from basalis maintenance cellular environment, promote the secretion of the water lock compositions such as collagen, play deep layer multiple-effect moisture-keeping function.It is and saturating
Bright matter acid sodium, layer protecting film mainly is formed in skin surface, strengthen skin barrier function, pin moisture.Yeast lysis thing carries
Take thing that skin can be promoted to synthesize hyaluronic acid, elastin laminin and collagen, absorption of the increase skin to moisture, while can press down
Free radical processed, increase cell aerobic respiration, lift cell consumption rate, promote cell metabolism, reduce oxidative stress.Can be effective
Free radical is neutralized, is enhanced metabolism.The compounding of several active components of the present invention, is not merely moisturizing or benefit in traditional sense
Water effect, but while moisturizing moisturizing, maintenance is damaged skin, understands free radical in skin, provides energy for skin, makes flesh
The restorative water profit state of skin.
Brief description of the drawings
Fig. 1 be facial treatment essence liquid use before, the keratoderma change of moisture content of 4 hours after 1 hour and use after use
Rate figure.
Fig. 2 is volunteer's wrinkle depth analysis chart.
Embodiment
Facial treatment essence liquid provided by the invention is with Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extraction
Thing, Sodium Hyaluronate are main component, be aided with cosmetics often with matrix components for example NMF, thickener, preservative, chelating agent,
Essence and water are made.A part of specific embodiment is set forth below, and the present invention will be described, but is not intended to limit the interior of the present invention
Hold.
Embodiment 1
Form facial treatment essence liquid component and its relative content be:
The preparation method of above-mentioned facial treatment essence liquid, comprises the following steps:By water, 1,3- propane diols, acryloyldimethyl taurine
Ammonium/VP copolymers, xanthans and Sodium Hyaluronate are added in reaction pot, are opened stirring, are heated to 75 ~ 80 DEG C, are uniformly dispersed;
Open cooling circulating water, stirring cooling, when temperature is down to 40 ~ 45 DEG C, add Margarita extract, saccharomycete lysis thing extract,
Fructus psidii guajavae immaturus extract, essence and preservative are added in reaction pot, and homogeneous 1 minute, stirring and dissolving is complete;Continue stirring to be cooled to
Material temperature is less than 38 DEG C, stops stirring, terminates.
Embodiment 2
Form facial treatment essence liquid component and its relative content be:
The preparation method of above-mentioned facial treatment essence liquid, comprises the following steps:By water, glycerine, Sodium Polyacrylate, xanthans and hyalomitome
Sour sodium is added in reaction pot, is opened stirring, is heated to 75 ~ 80 DEG C, is uniformly dispersed;Cooling circulating water is opened, stirring cooling, treats temperature
When being down to 40 ~ 45 DEG C, add Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, essence and preservative and add
Enter in reaction pot, homogeneous 1 minute, stirring and dissolving is complete;Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
Embodiment 3
Form facial treatment essence liquid component and its relative content be:
The preparation method of above-mentioned facial treatment essence liquid, comprises the following steps:By water, 1,3- propane diols, pungent glycol, acryloyldimethyl
Taurine ammonium/VP copolymers, xanthans and Sodium Hyaluronate are added in reaction pot, are opened stirring, are heated to 75 ~ 80 DEG C, are disperseed
Uniformly;Cooling circulating water is opened, stirring cooling, when temperature is down to 40 ~ 45 DEG C, adds Margarita extract, saccharomycete lysis thing carries
Thing, Fructus psidii guajavae immaturus extract, essence and preservative is taken to add in reaction pot, homogeneous 1 minute, stirring and dissolving is complete;Continue to stir
Material temperature is cooled to less than 38 DEG C, stops stirring, is terminated.
Embodiment 4
Form facial treatment essence liquid component and its relative content be:
The preparation method of above-mentioned facial treatment essence liquid, comprises the following steps:By water, 1,3- propane diols, hydroxy-ethyl acrylate/acryloyl
Dimethyltaurine sodium copolymer and combinations thereof and Sodium Hyaluronate are added in reaction pot, are opened stirring, are heated to 75 ~ 80
DEG C, it is uniformly dispersed;Cooling circulating water is opened, stirring cooling, when temperature is down to 40 ~ 45 DEG C, it is molten to add Margarita extract, saccharomycete
Born of the same parents' thing extract, Fructus psidii guajavae immaturus extract, essence and preservative are added in reaction pot, and homogeneous 1 minute, stirring and dissolving is complete;After
Continuous stirring is cooled to material temperature less than 38 DEG C, stops stirring, terminates.
Embodiment 5
Form facial treatment essence liquid component and its relative content be:
The preparation method of above-mentioned facial treatment essence liquid, comprises the following steps:By water, glycerine, butanediol, acryloyldimethyl taurine
Ammonium/VP copolymers and Sodium Hyaluronate are added in reaction pot, are opened stirring, are heated to 75 ~ 80 DEG C, are uniformly dispersed;Cooling is opened to follow
Ring water, stirring cooling, when temperature is down to 40 ~ 45 DEG C, add Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus
Extract, essence and preservative are added in reaction pot, and homogeneous 1 minute, stirring and dissolving is complete;Continue stirring and be cooled to material temperature to be less than
38 DEG C, stop stirring, terminate.
The moisture-keeping efficacy of embodiment 6 is evaluated
The facial treatment essence liquid provided in this experimental selection embodiment 1 carries out clinical trial.
The experiment includes 22 volunteers, and the age is in 21-45 one full year of life.Tested material and data are used according to regulations during experiment
It is complete.It is unified to clean both hands inner forearm before experiment, carry out measurement markers.Product smear zone and blank district random distribution
Region is demarcated in left and right arm, it is ensured that all product and white space positions statistically reach balance.First measure each region
Initial value, then test sample is pressed into ormal weight single application.In setting time point product is carried out using moisture of skin tester
Region and the measurement of control zone, each region parallel determination 5 times, record of averaging.
According to formula keratoderma change of moisture content rate=[(Th-T0)- (Th blank-T0 blank)]/T0, calculate skin care
Before Essence use, the keratoderma change of moisture content rate of 4 hours after 1 hour and use after use, see Fig. 1.As a result show,
Facial treatment essence liquid makes keratoderma water content after 1h have to improve a lot, and can obtain within 4 hours after use compared with
Good maintenance.
The instant anti-wrinkle effect assessment of embodiment 7
The facial treatment essence liquid provided in this experimental selection embodiment 1 carries out clinical trial.
The experiment includes 5 volunteers, and the age is in 25-45 one full year of life.Appropriate facial treatment essence liquid is taken to be applied at eye microgroove.
Eye is flicked with finger pulp loss all to absorb to sample.With imported from America VISIA-CR professional skin image analysis systems to eye
Portion's wrinkle of skin index using it is preceding and using 30 minutes after analyzed.After having used facial treatment essence liquid 30 minutes, wrinkle is deep
Degree is shown in a certain position volunteer wrinkle depth analysis charts of Fig. 2 than reducing 10% before use.Ridge part represents skin bulge in Fig. 2
Part, ridge part is more, represents that wrinkle of skin is fewer.
Claims (10)
1. a kind of facial treatment essence liquid, it is characterised in that the facial treatment essence liquid includes following component by mass percentage:
Margarita extract 0.01 ~ 20%
Saccharomycete lysis thing extract 0.01 ~ 10%
Fructus psidii guajavae immaturus extract 0.01 ~ 20%
Sodium Hyaluronate 0.001 ~ 1%;
Surplus is that facial treatment essence liquid often uses matrix and water.
A kind of 2. facial treatment essence liquid according to claim 1, it is characterised in that the facial treatment essence liquid by mass percentage
Including following component:
Margarita extract 0.1 ~ 10%
Saccharomycete lysis thing extract 0.05 ~ 5%
Fructus psidii guajavae immaturus extract 0.1 ~ 10%
Sodium Hyaluronate 0.01 ~ 0.2%;
Surplus is that facial treatment essence liquid often uses matrix and water.
A kind of 3. facial treatment essence liquid according to claim 1, it is characterised in that the facial treatment essence liquid by mass percentage
Including following component:
Margarita extract 0. 5 ~ 5%
Saccharomycete lysis thing extract 0.1 ~ 5%
Fructus psidii guajavae immaturus extract 0.5 ~ 5%
Sodium Hyaluronate 0.02 ~ 0.15%;
Surplus is that facial treatment essence liquid often uses matrix and water.
4. a kind of facial treatment essence liquid according to claim 1 ~ 3 any one claim, it is characterised in that by quality hundred
Divide and be often made up of than meter facial treatment essence liquid with matrix following component:
1,3- propane diols 1 ~ 20%
Ammonium acryloyldime-thyltaurate/VP copolymers 0.1 ~ 2%
Xanthans 0.01 ~ 0.5%
Essence 0.01 ~ 0.5%
Preservative qs.
5. a kind of facial treatment essence liquid according to claim 1 ~ 3 any one claim, it is characterised in that by quality hundred
Divide and be often made up of than meter facial treatment essence liquid with matrix following component:
1,3- propane diols 2 ~ 10%
Ammonium acryloyldime-thyltaurate/VP copolymers 0.2 ~ 1%
Xanthans 0.05 ~ 0.2%
Essence 0.05 ~ 0.2%
Preservative qs.
6. a kind of facial treatment essence liquid according to claim 1 ~ 3 any one claim, it is characterised in that pearl is extracted
Thing is the mixture of a variety of peptides that pearl powder obtains through enzymolysis and amino acid;Content of peptides is in 1.0- in Margarita extract
Between 20.0mg/ml, solid content is between 2.0-20.0%.
A kind of 7. facial treatment essence liquid according to claim 1 ~ 3 any one claim, it is characterised in that female bacterium lysis
Thing extract, it is yeast cells caused metabolite under controlled ambient pressure condition of culture, is extracted through breaking-wall cell
Get, by including amino acid, glycopeptide, the material composition of nucleotides and other low relative molecular masses, the extract is non-volatile
Thing content is between 25%-40%.
A kind of 8. facial treatment essence liquid according to claim 1 ~ 3 any one claim, it is characterised in that Fructus psidii guajavae immaturus
Extract solid content is in 1%-2%.
A kind of 9. facial treatment essence liquid according to claim 1 ~ 3 any one claim, it is characterised in that hyaluronic acid
Sodium molecule amount is distributed in 1.0*105Da and 3.0*106Between Da, purity is more than 90%.
A kind of 10. method for preparing a kind of facial treatment essence liquid described in claim 4 or 5, it is characterised in that this method include with
Under step:
1)Water, 1,3- propane diols, ammonium acryloyldime-thyltaurate/VP copolymers, xanthans and Sodium Hyaluronate are added anti-
Answer in pot, open stirring, be heated to 75 ~ 80 DEG C, be uniformly dispersed;
2)Cooling circulating water is opened, stirring cooling, when temperature is down to 40 ~ 45 DEG C, adds Margarita extract, saccharomycete lysis thing carries
Thing, Fructus psidii guajavae immaturus extract, essence and preservative is taken to add in reaction pot, homogeneous 1 minute, stirring and dissolving is complete;
3)Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
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CN110101649A (en) * | 2019-06-18 | 2019-08-09 | 欧诗漫生物股份有限公司 | Cosmetic composition and its application, product and preparation method using it |
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CN112842976B (en) * | 2019-11-28 | 2024-01-02 | 浙江养生堂天然药物研究所有限公司 | Yeast fermented birch juice and its application in anti-inflammatory cosmetic composition |
CN111920750A (en) * | 2020-09-01 | 2020-11-13 | 广州市鑫晞莱生物科技有限公司 | Preparation method of skin care essence stock solution |
CN115381754A (en) * | 2021-10-14 | 2022-11-25 | 广州花出见生物科技有限公司 | Supermolecule permeation type muscle bottom repairing liquid and preparation method thereof |
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