CN115381754B - Supermolecule permeation type muscle bottom repairing liquid and preparation method thereof - Google Patents
Supermolecule permeation type muscle bottom repairing liquid and preparation method thereof Download PDFInfo
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- CN115381754B CN115381754B CN202111199803.0A CN202111199803A CN115381754B CN 115381754 B CN115381754 B CN 115381754B CN 202111199803 A CN202111199803 A CN 202111199803A CN 115381754 B CN115381754 B CN 115381754B
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- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 229940045944 sodium lauroyl glutamate Drugs 0.000 description 1
- IWIUXJGIDSGWDN-UQKRIMTDSA-M sodium;(2s)-2-(dodecanoylamino)pentanedioate;hydron Chemical compound [Na+].CCCCCCCCCCCC(=O)N[C@H](C([O-])=O)CCC(O)=O IWIUXJGIDSGWDN-UQKRIMTDSA-M 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229940104261 taurate Drugs 0.000 description 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9741—Pteridophyta [ferns]
- A61K8/9749—Filicopsida or Pteridopsida
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A61Q19/00—Preparations for care of the skin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention relates to the field of IPC A61K8/00, in particular to supermolecule permeation type muscle bottom repairing liquid and a preparation method thereof. The raw materials comprise, by weight: 2-30% of small molecular polyalcohol, 0.1-3% of rheological additive, 0.8-15% of humectant, 0.1-15% of supermolecular compound, 0.2-20% of skin conditioner, 0.1-15% of plant extract, 0.01-1% of pH regulator, 0.05-2% of amino acid surface activity, 0.1-1.5% of stabilizer and the balance of solvent. The supermolecular compound is adopted to jointly act with the raw materials such as the glyceroglycosides, the specific plant extracts and the like, so as to achieve the multiple repairing effects of relieving, resisting inflammation, supplementing water and promoting the metabolism of skin tissues.
Description
Technical Field
The invention relates to the field of IPC A61K8/00, in particular to supermolecule permeation type muscle bottom repairing liquid and a preparation method thereof.
Background
The existing market investigation information shows that the repair products on the market are numerous at present, but as urban environment changes, air pollution and life style change, sensitive muscle consumers are increased gradually, and the repair of the sensitive muscle is poor due to the fact that the number of the products on the market is too large; or only consider concept addition to claim repair, and do not relate to long-acting repair of sensitive skin, or are not friendly to sensitive muscles, and the demand of sensitive muscle consumers on repair products is not fully satisfied.
Chinese patent CN201611027865.2 discloses a multifunctional preparation for removing acne and eliminating scar and caring skin and its preparation method, which uses hyaluronic acid and polyglutamic acid with different molecular weights, collagen peptide and the like to achieve the effect of repairing skin tissue; chinese patent CN201910160799.3 discloses a cosmetic composition for postoperative repair, spray and preparation method thereof, which adopts the combined action of polyalcohol, small molecule sodium hyaluronate, cordyceps sinensis extract, cell respiratory factor, etc., and solves the problem of wound repair after cosmetic operation. However, the repair problem of sensitive muscles is not thoroughly solved in the prior art, and the cost and the efficacy are difficult to be compatible.
Aiming at the current situation, the invention aims to develop a product with various skin types and excellent effects of repairing sensitive skin, and the formula is designed from the following thought to cooperatively achieve the effects of repairing the sensitive skin in a multi-dimensional way.
Disclosure of Invention
The problem factors of the repair sensitive skin products in the current market are several, namely 1, the components are added conceptually, 2, the efficacy of the raw materials is single, 3, the cost is low, no high-quality raw materials are added, and the products are sold in a flow way. The efficacy and quality of the repairing products circulated in the market are difficult to ensure at present.
In order to solve the problems, the first aspect of the invention provides a supermolecule permeation type muscle base repairing liquid, which comprises the following raw materials in percentage by weight: 2-30% of small molecular polyalcohol, 0.1-3% of rheological additive, 0.8-15% of humectant, 0.1-15% of supermolecular compound, 0.2-20% of skin conditioner, 0.1-15% of plant extract, 0.01-1% of pH regulator, 0.05-2% of amino acid surface activity, 0.1-1.5% of stabilizer and the balance of solvent.
In some preferred embodiments, the small molecule polyol comprises a combination of one or more of glycerol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, and octyloxy glycerol.
Further preferably, the small molecule polyols include glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol, and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is (0.5-6): 2-10): 0.5-10): 0.1-2.5: (0.1-2.5).
The invention selects the mild and non-irritating raw materials in the research and development process of the formula, and selects the specific micromolecular polyol and the plant extract to act together on the basis of the conception of no preservative addition through a large number of experimental researches, so that the stability of the repairing liquid is improved, and the repairing liquid can be stably stored for a long time under the conditions of high temperature and low temperature. Meanwhile, an acid-base-free neutralizer is selected in the formula to regulate thickening suspension, so that skin irritation is avoided, and the repairing liquid can be safely applied to sensitive skin and is easier to be absorbed by the skin.
In some preferred embodiments, the rheology aid is a combination of one or more of xanthan gum, carrageenan, gelatin, alginate, cellulose and derivatives thereof, ammonium acrylodimethyltaurate/VP copolymer.
Further preferably, the rheology aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of the xanthan gum to the acrylamide/VP copolymer is (0.05-1): 0.1-2.
In some preferred embodiments, the humectant comprises hyaluronic acid and derivatives thereof, glyceroglycosides, phosphatidylcholine, amide compositions, allantoin, polyethylene glycol, sorbitol, panthenol in combination with one or more of the foregoing.
Further preferably, the moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglycosides, phosphatidylcholine and amide compositions; the weight ratio of the hyaluronic acid and the derivatives thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is (0.06-1.5): (0.1-2): (0.1-6). The invention selects the specific humectant to play roles in repairing liquid, effectively playing roles of resisting aging, stimulating cell regeneration, locking water and moisturizing, and enhancing skin elasticity.
Preferably, the hyaluronic acid and its derivatives are in particular sodium hyaluronate hydrolysate, which is commercially available, for example from the company Henan Kangwang Biotechnology Co.
In some preferred embodiments, the amide composition is ceramide NP and nicotinamide; the weight ratio of the ceramide NP to the nicotinamide is (0.01-10): 0.3-3; ceramide NP may be commercially available, for example, from Guangdong Biotechnology Co., ltd, and nicotinamide may be commercially available, for example, from Guangzhou City Ming Biotechnology Co., ltd.
In some preferred embodiments, the skin conditioning agent comprises a combination of any one or more of a saccharomyces cerevisiae fermentation product filtrate, hydrolyzed silk, coenzyme Q10, jojoba oil.
Further preferably, the skin conditioning agent comprises a saccharomyces cerevisiae fermentation product filtrate and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is (0.1-20) to (0.01-0.5). The fermentation product filtrate of the Saccharomyces cerevisiae may be commercially available, for example, from SiAnweis Bo Biotechnology Co., ltd, and the hydrolyzed silk may be commercially available, for example, from Suzhou silkworm Biocompany.
In some preferred embodiments, the starting materials for the supramolecular compound include glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is (0.1-12) to (0.3-4).
Further preferably, the supramolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supramolecular self-assembly technology. The invention adopts glycyrrhizic acid and arginine to spontaneously polymerize, identify and form a supermolecule ionic salt compound with stable structure through a supermolecule modification technology and a supermolecule self-assembly technology. The obtained ionic liquid can be used as a skin permeation carrier to gently carry out physical permeation on the stratum corneum, and the diffusion and transportation of the repair layer between the lipid bilayer and the stratum corneum cells are improved, so that the effects of resisting aging and relaxing the sensitivity are achieved.
The supermolecular compound is added into the formula, so that the effects of relieving, inhibiting bacteria, resisting inflammation, supplementing water and promoting cutin update of the repairing liquid are improved, the effects of relieving sensitive skin, repairing skin barriers, relieving skin inflammatory reaction, inhibiting inflammatory factors and medium activity are achieved, the defect that glycyrrhizic acid is poor in solubility and insoluble in cold water and extremely high in compatibility requirement on the formula is overcome by combining arginine and glycyrrhizic acid, the obtained supermolecular compound can be mutually dissolved with water in any proportion, the permeation effect of the repairing liquid on the skin barriers is promoted, active ingredients in raw materials can play a role better, and the bioavailability of nutritional factors is improved.
In some preferred embodiments, the plant extract comprises a combination of one or more of chamomile extract, purslane extract, houttuynia extract, scutellaria root extract, peony root bark extract, opuntia ficus tikoua stem extract, aloe extract, calendula extract, pachyma Luo Mu extract, and pteris multifida extract.
Further preferably, the plant extract comprises chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract, and Opuntia Dillenii (OPUNTIA STREPTACANTHA) stem extract.
Still more preferably, the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is (0.1-2): (0.2-5): (0.1-2): (0.05-4): (0.01-3): (0.05-5). According to the invention, the specific plant extract composition is selected to act together, and bioactive components such as polysaccharide, vitamin, mineral, paeonol, flavone, triterpene and the like in the extract permeate into the skin to exert the effects of relieving the skin, improving blood circulation, diminishing inflammation, resisting bacteria, inhibiting bacteria, eliminating marks, resisting oxidation and the like, so that the skin problem is effectively repaired, the repairing effect of the repairing liquid on the skin is improved, and the skin is enabled to recover elasticity and tender.
The latin theory of golden chamomile extract is Anthenis Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of radix Scutellariae extract is Scutellaria baicalensis Georgi, the latin theory of Paeoniasurruticica Andr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, and the PLANT extract is from PLANT21.
According to the invention, the supermolecular compound is added into the repairing liquid formula to act together with the glyceroglycosides and the specific Plant extract (Plant 21), so that the repairing method of multiple barrier damage which is anti-inflammatory, antibacterial, moisturizing, sun-screening and excessive cleaning prevention is achieved. The specific active ingredients act together, so that the antibacterial and anti-inflammatory effects can be achieved, the moisture content in skin tissues can be improved, and the antibacterial and anti-inflammatory skin tissue repair agent is the best choice for skin barrier repair.
In some preferred embodiments, the pH adjuster has a melting point of 140-165 ℃, a boiling point of 160-184 ℃, preferably citric acid.
The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
In some preferred embodiments, the amino acid surfactant is one or more of sodium stearoyl glutamate, sodium lauroyl glutamate, potassium cocoyl glutamate, TEA cocoyl glutamate salt; sodium stearoyl glutamate is preferred.
In some preferred embodiments, the stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is (0.1-1): 1.
In some preferred embodiments, the solvent is water.
The second aspect of the present embodiment provides a method for preparing the supramolecular penetration type muscle base repair liquid, wherein the specific preparation steps of the supramolecular penetration type muscle base repair liquid include: mixing the raw materials at 30-85deg.C, dispersing uniformly, filtering, and discharging to obtain the final product.
Further preferably, the specific preparation steps of the supermolecule permeable muscle base repair liquid comprise:
s1, mixing glycerol, xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer, uniformly dispersing, adding water and p-hydroxyacetophenone, heating to 85 ℃, and dissolving and uniformly dispersing;
s2, cooling to 60 ℃, adding 1, 3-propylene glycol and hydrolyzed sodium hyaluronate, and dissolving and dispersing uniformly;
s3, continuously cooling to 45 ℃, adding other raw materials, uniformly stirring, filtering and discharging to obtain a finished product.
Drawings
FIG. 1 is a graph of the comparison of facial inflammation before and after use of subject A (a: front face, b: rear face, c: front face, d: rear face);
FIG. 2 shows a comparison of facial inflammation before and after use (a: front right face, B: rear right face, c: front left face, d: rear left face) for subject B;
the beneficial effects are that:
the supermolecule permeation type muscle base repairing liquid provided by the invention has the following advantages:
(1) The supermolecular compound, the glyceroglycosides and the specific plant extracts are adopted to act together, so that the multiple repairing effects of relieving, resisting inflammation, supplementing water and promoting the metabolism of skin tissues are achieved, and the skin barrier is effectively repaired;
(2) The obtained repairing liquid can be suitable for various skins, is safe and mild, has no stimulation, is easy to be absorbed by the skins, has high bioavailability of active biological factors, and can act on various skins (especially sensitive skins);
(3) The problems of poor solubility of active raw materials are obviously improved by adopting the combined action of the raw materials such as micromolecular polyalcohol, plant extract and the like and the active ingredients, and the obtained repairing liquid has strong stability and wide temperature resistance.
Detailed Description
Example 1.
The supermolecule permeation type muscle bottom repairing liquid comprises the following raw materials in percentage by weight: 6.5% of small molecular polyalcohol, 0.2% of rheological additive, 1.3% of humectant, 0.6% of supermolecular compound, 0.6% of skin conditioning agent, 1% of plant extract, 0.1% of pH regulator, 0.1% of amino acid surfactant, 0.2% of stabilizer and the balance of solvent.
The small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 1:3:1:0.5:0.5:0.5.
the rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of xanthan gum to acrylamide dimethyl taurate/VP copolymer is 1:1.
The moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid to the derivative thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 0.1:0.1:0.5:0.6.
The hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate, and the hydrolyzed sodium hyaluronate is derived from Henan kang Wang Biotechnology Co.
The amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 1:5; ceramide NP is available from guangdong biotechnology, inc, and nicotinamide is available from guangzhou, inc.
The glyceroglycosides are derived from Shenzhen Hemerocallis, calif. Biotechnology.
The skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 5:1. The fermentation product filtrate of the two-split yeast is from SiAnweis Bo biotechnology Co., ltd, and the hydrolyzed silk is from Suzhou silkworm biological Co.
The raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 1:5.
The supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology, and is derived from Shenzhen Hemerocallis, jia Biotechnology Co.
The plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 1:5:1:1:1:1.
The latin theory of golden chamomile extract is Anthenics Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of Scutellaria baicalensis Georgi, the latin theory of Paeonia suffruticosa bark extract is PaeoniasuricosaAndr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, the PLANT extract is derived from, under the trade name PLANT21, from Shanghai intercontinents.
The pH regulator is citric acid. The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
The amino acid surface activity is sodium stearyl glutamate.
The stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 1:1.
The solvent is water.
The second aspect of the present embodiment provides a preparation method of the supramolecular penetration type muscle base repair liquid, which specifically includes the following preparation steps:
s1, mixing glycerol, xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer, uniformly dispersing, adding water and p-hydroxyacetophenone, heating to 85 ℃, and dissolving and uniformly dispersing;
s2, cooling to 60 ℃, adding 1, 3-propylene glycol and hydrolyzed sodium hyaluronate, and dissolving and dispersing uniformly;
s3, continuously cooling to 45 ℃, adding other raw materials, uniformly stirring, filtering and discharging to obtain a finished product.
Example 2.
The supermolecule permeation type muscle bottom repairing liquid comprises the following raw materials in percentage by weight: 14% of small molecular polyalcohol, 0.8% of rheological additive, 3% of humectant, 2% of supermolecular compound, 5.1% of skin conditioning agent, 4.5% of plant extract, 0.1% of pH regulator, 0.2% of amino acid surfactant, 0.8% of stabilizer and the balance of solvent.
The small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 3:5:3:1:1:1.
The rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of xanthan gum to ammonium acryloyldimethyl taurate/VP copolymer was 2:6.
The moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid and the derivatives thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 0.2:0.5:0.8:1.5.
The hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate, and the hydrolyzed sodium hyaluronate is derived from Henan kang Wang Biotechnology Co.
The amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 0.5:1; ceramide NP is available from guangdong biotechnology, inc, and nicotinamide is available from guangzhou, inc.
The glyceroglycosides are derived from Shenzhen Hemerocallis, calif. Biotechnology.
The skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 5:0.1. The fermentation product filtrate of the two-split yeast is from SiAnweis Bo biotechnology Co., ltd, and the hydrolyzed silk is from Suzhou silkworm biological Co.
The raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 1:1.
The supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology, and is derived from Shenzhen Hemerocallis, jia Biotechnology Co.
The plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 0.5:1:0.5:1:0.5:1.
The latin theory of golden chamomile extract is Anthenics Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of Scutellaria baicalensis Georgi, the latin theory of Paeonia suffruticosa bark extract is PaeoniasuricosaAndr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, the PLANT extract is derived from, under the trade name PLANT21, from Shanghai intercontinents.
The pH regulator is citric acid. The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
The amino acid surface activity is sodium stearyl glutamate.
The stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 3:5.
The solvent is water.
The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
Example 3.
The supermolecule permeation type muscle bottom repairing liquid comprises the following raw materials in percentage by weight: 25.5% of small molecular polyalcohol, 0.8% of rheological additive, 6.8% of humectant, 6.5% of supermolecular compound, 10.2% of skin conditioning agent, 10.5% of plant extract, 0.1% of pH regulator, 0.3% of amino acid surfactant, 0.8% of stabilizer and the balance of solvent.
The small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 5:8:8:1.5:1.5:1.5.
The rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of xanthan gum to acrylamide/VP copolymer was 0.2:0.6.
The moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid and the derivatives thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 0.5:2.5:0.8:1.5.
The hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate, and the hydrolyzed sodium hyaluronate is derived from Henan kang Wang Biotechnology Co.
The amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 5:1.5; ceramide NP is available from guangdong biotechnology, inc, and nicotinamide is available from guangzhou, inc.
The glyceroglycosides are derived from Shenzhen Hemerocallis, calif. Biotechnology.
The skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 5:0.1. The fermentation product filtrate of the two-split yeast is from SiAnweis Bo biotechnology Co., ltd, and the hydrolyzed silk is from Suzhou silkworm biological Co.
The raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 1:5.
The supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology, and is derived from Shenzhen Hemerocallis, jia Biotechnology Co.
The plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 1:3:1:2:1.5:2.
The latin theory of golden chamomile extract is Anthenics Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of Scutellaria baicalensis Georgi, the latin theory of Paeonia suffruticosa bark extract is PaeoniasuricosaAndr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, the PLANT extract is derived from, under the trade name PLANT21, from Shanghai intercontinents.
The pH regulator is citric acid. The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
The amino acid surface activity is sodium stearyl glutamate.
The stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 3:5.
The solvent is water.
The preparation steps of the supermolecule permeation type muscle base repair liquid are the same as those of the example 1.
Example 4.
The supermolecule permeation type muscle bottom repairing liquid comprises the following raw materials in percentage by weight: 21% of small molecular polyalcohol, 1% of rheological additive, 11% of humectant, 10.5% of supermolecular compound, 15.2% of skin conditioning agent, 11% of plant extract, 0.1% of pH regulator, 0.5% of amino acid surfactant, 1% of stabilizer and the balance of solvent.
The small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 5:5:5:2:2:2.
The rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of xanthan gum to acrylamide/VP copolymer was 0.2:0.6.
The moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid to the derivatives thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 1:5:1:4.
The hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate, and the hydrolyzed sodium hyaluronate is derived from Henan kang Wang Biotechnology Co.
The amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 3:1; ceramide NP is available from guangdong biotechnology, inc, and nicotinamide is available from guangzhou, inc.
The glyceroglycosides are derived from Shenzhen Hemerocallis, calif. Biotechnology.
The skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 8:2.5. The fermentation product filtrate of the two-split yeast is from SiAnweis Bo biotechnology Co., ltd, and the hydrolyzed silk is from Suzhou silkworm biological Co.
The raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 8:2.5.
The supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology, and is derived from Shenzhen Hemerocallis, jia Biotechnology Co.
The plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 1:3:1:2:2:2.
the latin theory of golden chamomile extract is Anthenics Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of Scutellaria baicalensis Georgi, the latin theory of Paeonia suffruticosa bark extract is PaeoniasuricosaAndr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, the PLANT extract is derived from, under the trade name PLANT21, from Shanghai intercontinents.
The pH regulator is citric acid. The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
The amino acid surface activity is sodium stearyl glutamate.
The stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 1:1.
The solvent is water.
The preparation steps of the supermolecule permeation type muscle base repair liquid are the same as those of the example 1.
Comparative example 1.
The supermolecule permeation type muscle bottom repairing liquid comprises the following raw materials in percentage by weight: 25.5% of small molecular polyalcohol, 1.3% of rheological additive, 6.8% of humectant, 6.5% of supermolecular compound, 10.2% of skin conditioning agent, 10.5% of plant extract, 0.1% of pH regulator, 0.3% of amino acid surfactant, 0.8% of stabilizer and the balance of solvent.
The small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 5:8:8:1.5:1.5:1.5.
The rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of xanthan gum to ammonium acryloyldimethyl taurate/VP copolymer was 0.3:1.
The moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid and the derivatives thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 0.5:2.5:0.8:1.5.
The hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate, and the hydrolyzed sodium hyaluronate is derived from Henan kang Wang Biotechnology Co.
The amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 5:1.5; ceramide NP is available from guangdong biotechnology, inc, and nicotinamide is available from guangzhou, inc.
The glyceroglycosides are derived from Shenzhen Hemerocallis, calif. Biotechnology.
The skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 5:0.1. The fermentation product filtrate of the two-split yeast is from SiAnweis Bo biotechnology Co., ltd, and the hydrolyzed silk is from Suzhou silkworm biological Co.
The raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 1:5.
The supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology, and is derived from Shenzhen Hemerocallis, jia Biotechnology Co.
The plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 1:3:1:2:1.5:2.
The latin theory of golden chamomile extract is Anthenics Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of Scutellaria baicalensis Georgi, the latin theory of Paeonia suffruticosa bark extract is PaeoniasuricosaAndr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, the PLANT extract is derived from, under the trade name PLANT21, from Shanghai intercontinents.
The pH regulator is citric acid. The melting point of the citric acid is 153 ℃ and the boiling point is 175 ℃.
The amino acid surface activity is sodium stearyl glutamate.
The stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 3:5.
The solvent is water.
The preparation steps of the supermolecule permeation type muscle base repair liquid are the same as those of the example 1.
Comparative example 2.
The supermolecule permeation type muscle bottom repairing liquid comprises the following raw materials in percentage by weight: 21% of small molecular polyol, 1.5% of rheological additive, 11% of humectant, 10.5% of supermolecular compound, 15.2% of skin conditioning agent, 11% of plant extract, 0.1% of pH regulator, 0.5% of amino acid surfactant, 1% of stabilizer and the balance of solvent.
The small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 5:5:5:2:2:2.
The rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of xanthan gum to ammonium acryloyldimethyl taurate/VP copolymer was 0.5:1.
The moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid to the derivatives thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 1:5:1:4.
The hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate, and the hydrolyzed sodium hyaluronate is derived from Henan kang Wang Biotechnology Co.
The amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 3:1; ceramide NP is available from guangdong biotechnology, inc, and nicotinamide is available from guangzhou, inc.
The glyceroglycosides are derived from Shenzhen Hemerocallis, calif. Biotechnology.
The skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 8:2.5. The fermentation product filtrate of the two-split yeast is from SiAnweis Bo biotechnology Co., ltd, and the hydrolyzed silk is from Suzhou silkworm biological Co.
The raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 8:2.5.
The supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology, and is derived from Shenzhen Hemerocallis, jia Biotechnology Co.
The plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 1:3:1:2:2:2.
the latin theory of golden chamomile extract is Anthenics Nobilis, the latin theory of purslane extract is Portulaca oleracea L., the latin theory of houttuynia cordata extract is Houttuyniae cordata Thunb, the latin theory of Scutellaria baicalensis Georgi, the latin theory of Paeonia suffruticosa bark extract is PaeoniasuricosaAndr, the latin theory of Opuntia spinosa stem extract is Opuntia fillenii (Ker Gawl.) Haw, the PLANT extract is derived from, under the trade name PLANT21, from Shanghai intercontinents.
The amino acid surface activity is sodium stearyl glutamate.
The stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 1:1.
The solvent is water.
The preparation steps of the supermolecule permeation type muscle base repair liquid are the same as those of the example 1.
Performance test method
1. Stability test
The repairing liquids provided in examples and comparative examples were subjected to stability tests at different temperatures, and whether delamination, thickening and deterioration occurred was observed and recorded in table 1.
2. Anti-inflammatory repair effect
2 subjects (subject A and subject B) were screened and after 28 days of continuous use of example 2, facial inflammatory changes were observed, see in particular FIGS. 1-2.
As shown in figures 1-2, the repairing liquid provided by the invention can obviously improve the facial inflammation of a subject after 28 days continuously, and the repairing liquid provided by the invention has excellent anti-inflammatory and relieving effects.
Performance test data
Table 1.
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Claims (2)
1. The supermolecule permeation type muscle bottom repairing liquid is characterized by comprising the following raw materials in percentage by weight: 14% of small molecular polyalcohol, 0.8% of rheological additive, 3% of humectant, 2% of supermolecular compound, 5.1% of skin conditioning agent, 4.5% of plant extract, 0.1% of pH regulator, 0.2% of amino acid surfactant, 0.8% of stabilizer and the balance of solvent;
the small molecule polyalcohol comprises glycerol, 1, 3-propanediol, 1, 4-butanediol, 1, 2-pentanediol, 1, 2-hexanediol and octoxyglycerol; the weight ratio of the glycerol, the 1, 3-propylene glycol, the 1, 4-butanediol, the 1, 2-pentanediol, the 1, 2-hexanediol and the octoxyglycerol is 3:5:3:1:1:1;
the rheological aid is xanthan gum and an ammonium acryloyldimethyl taurate/VP copolymer; the weight ratio of the xanthan gum to the ammonium acryloyldimethyl taurate/VP copolymer is 2:6;
the moisturizer comprises hyaluronic acid and derivatives thereof, glyceroglyceride, phosphatidylcholine and amide composition; the weight ratio of the hyaluronic acid to the derivative thereof, the glyceroglycosides, the phosphatidylcholine and the amide composition is 0.2:0.5:0.8:1.5;
the hyaluronic acid and the derivatives thereof are specifically hydrolyzed sodium hyaluronate;
the amide composition is ceramide NP and nicotinamide; the weight ratio of ceramide NP to nicotinamide is 0.5:1;
the skin conditioner comprises a fermentation product filtrate of the saccharomyces cerevisiae and hydrolyzed silk; the weight ratio of the fermentation product filtrate of the saccharomyces cerevisiae to the hydrolyzed silk is 5:0.1;
the raw materials of the supermolecular compound comprise glycyrrhizic acid and arginine; the weight ratio of glycyrrhizic acid to arginine is 1:1;
the supermolecular compound is specifically prepared from glycyrrhizic acid and arginine by a supermolecular self-assembly technology;
the plant extracts comprise chamomile (CHRYSANTHELLUM INDICUM) extract, purslane (PORTULACA OLERACEA) extract, houttuynia cordata (HOUTTUYNIA CORDATA) extract, scutellaria baicalensis (SCUTELLARIA BAICALENSIS) root extract, peony (PAEONIA SUFFRUTICOSA) root bark extract and Cactus (OPUNTIA STREPTACANTHA) stem extract; the mass ratio of the golden chamomile extract, the purslane extract, the cordate houttuynia extract, the baical skullcap root extract, the tree peony root bark extract and the Cactus body stem extract is 0.5:1:0.5:1:0.5:1;
the pH regulator is citric acid; the melting point of the citric acid is 153 ℃ and the boiling point of the citric acid is 175 ℃;
the amino acid surfactant is sodium stearyl glutamate;
the stabilizer comprises p-hydroxyacetophenone and octanoyl hydroxamic acid; the weight ratio of the p-hydroxyacetophenone to the octanoyl hydroxamic acid is 3:5;
the solvent is water.
2. A method of preparing the supramolecular penetration type muscle base repair liquid according to claim 1, wherein the preparing step of the supramolecular penetration type muscle base repair liquid comprises: mixing the raw materials at 30-85deg.C, dispersing uniformly, filtering, and discharging to obtain the final product.
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