CN104487587A - Cd3结合多肽 - Google Patents

Cd3结合多肽 Download PDF

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Publication number
CN104487587A
CN104487587A CN201380027109.8A CN201380027109A CN104487587A CN 104487587 A CN104487587 A CN 104487587A CN 201380027109 A CN201380027109 A CN 201380027109A CN 104487587 A CN104487587 A CN 104487587A
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seq
binding
territory
cell
binding domain
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P·H·坦
S·K·纳塔拉詹
C·J·麦克马汉
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Aptevo Research and Development LLC
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Emergent Product Development Seattle LLC
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201380027109.8A 2012-04-20 2013-04-18 Cd3结合多肽 Pending CN104487587A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261636557P 2012-04-20 2012-04-20
US61/636,557 2012-04-20
US201261718635P 2012-10-25 2012-10-25
US61/718,635 2012-10-25
US201361799849P 2013-03-15 2013-03-15
US61/799,849 2013-03-15
PCT/US2013/037135 WO2013158856A2 (en) 2012-04-20 2013-04-18 Cd3 binding polypeptides

Publications (1)

Publication Number Publication Date
CN104487587A true CN104487587A (zh) 2015-04-01

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US (1) US10202452B2 (enExample)
EP (1) EP2839019A4 (enExample)
JP (2) JP6509724B2 (enExample)
KR (1) KR20150004856A (enExample)
CN (1) CN104487587A (enExample)
AU (2) AU2013249267A1 (enExample)
BR (1) BR112014025830A8 (enExample)
CA (1) CA2870545A1 (enExample)
HK (2) HK1207398A1 (enExample)
IL (1) IL235093B (enExample)
IN (1) IN2014MN02293A (enExample)
MX (1) MX366813B (enExample)
RU (1) RU2673153C2 (enExample)
SG (2) SG11201406346SA (enExample)
UA (1) UA119227C2 (enExample)
WO (1) WO2013158856A2 (enExample)

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CN104892765A (zh) * 2015-06-29 2015-09-09 长春力太生物技术有限公司 一种抗CD3抗原和Her-2抗原的双特异性抗体
CN106084048A (zh) * 2016-06-17 2016-11-09 中山大学 抗cd3单域抗体
CN106084046A (zh) * 2016-06-17 2016-11-09 中山大学 抗cd3单域抗体
CN106084049A (zh) * 2016-06-17 2016-11-09 中山大学 抗cd3单域抗体
CN106084047A (zh) * 2016-06-17 2016-11-09 中山大学 抗cd3单域抗体
CN106117361A (zh) * 2016-06-17 2016-11-16 中山大学 抗cd3单域抗体
CN106117360A (zh) * 2016-06-17 2016-11-16 中山大学 抗cd3单域抗体
CN106117358A (zh) * 2016-06-16 2016-11-16 中山大学 抗cd3单域抗体
CN106117359A (zh) * 2016-06-17 2016-11-16 中山大学 抗cd3单域抗体
CN106146661A (zh) * 2016-06-17 2016-11-23 中山大学 抗cd3单域抗体
CN106146662A (zh) * 2016-07-18 2016-11-23 中山大学 抗cd3单域抗体
WO2017193956A1 (zh) * 2016-05-12 2017-11-16 李华顺 一种双特异性抗原结合构建体及其制备方法和应用
CN108026179A (zh) * 2015-10-02 2018-05-11 豪夫迈·罗氏有限公司 结合间皮素和cd3的双特异性t细胞活化性抗原结合分子
CN108137700A (zh) * 2015-07-31 2018-06-08 瑞泽恩制药公司 抗psma抗体、结合psma及cd3的双特异性抗原结合分子及其用途
CN108367004A (zh) * 2015-09-21 2018-08-03 阿帕特夫研究和发展有限公司 Cd3结合多肽
CN112533950A (zh) * 2018-06-29 2021-03-19 百奥赛图(北京)医药科技股份有限公司 抗CD3e抗体及其用途
CN112955471A (zh) * 2018-12-07 2021-06-11 江苏恒瑞医药股份有限公司 Cd3抗体及其药物用途
CN113005088A (zh) * 2019-12-19 2021-06-22 苏州方德门达新药开发有限公司 工程改造的t细胞、其制备及应用
US11339225B2 (en) 2016-05-12 2022-05-24 Asclepius (Suzhou) Technology Company Group, Co., Ltd. Bispecific antigen-binding construct and preparation method and use thereof
CN115029318A (zh) * 2022-05-12 2022-09-09 广州明征生物科技有限公司 携带多特异性抗体基因的间充质干细胞及其制药用途
CN115232213A (zh) * 2022-07-19 2022-10-25 合肥天港免疫药物有限公司 双特异性抗体及其应用

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