CN103998449A - 吡咯并苯并二氮杂卓 - Google Patents

吡咯并苯并二氮杂卓 Download PDF

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Publication number
CN103998449A
CN103998449A CN201280061972.0A CN201280061972A CN103998449A CN 103998449 A CN103998449 A CN 103998449A CN 201280061972 A CN201280061972 A CN 201280061972A CN 103998449 A CN103998449 A CN 103998449A
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菲利普·威尔逊·霍华德
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MedImmune Ltd
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ADC Products UK Ltd
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Priority to CN201910395572.7A priority Critical patent/CN110183470A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
CN201280061972.0A 2011-10-14 2012-10-12 吡咯并苯并二氮杂卓 Pending CN103998449A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910395572.7A CN110183470A (zh) 2011-10-14 2012-10-12 吡咯并苯并二氮杂卓

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161547204P 2011-10-14 2011-10-14
US61/547,204 2011-10-14
PCT/EP2012/070231 WO2013053871A1 (en) 2011-10-14 2012-10-12 Pyrrolobenzodiazepines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201910395572.7A Division CN110183470A (zh) 2011-10-14 2012-10-12 吡咯并苯并二氮杂卓

Publications (1)

Publication Number Publication Date
CN103998449A true CN103998449A (zh) 2014-08-20

Family

ID=47019018

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201280061972.0A Pending CN103998449A (zh) 2011-10-14 2012-10-12 吡咯并苯并二氮杂卓
CN201910395572.7A Pending CN110183470A (zh) 2011-10-14 2012-10-12 吡咯并苯并二氮杂卓

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201910395572.7A Pending CN110183470A (zh) 2011-10-14 2012-10-12 吡咯并苯并二氮杂卓

Country Status (9)

Country Link
US (1) US9388187B2 (enExample)
EP (1) EP2751110B1 (enExample)
JP (1) JP6117801B2 (enExample)
CN (2) CN103998449A (enExample)
AU (1) AU2012322932B2 (enExample)
BR (1) BR112014008981A2 (enExample)
CA (1) CA2850264C (enExample)
EA (1) EA027386B1 (enExample)
WO (1) WO2013053871A1 (enExample)

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