CN102670899A - Compound propolis composition for treating cattle and sheep fascioliasis and preparation method thereof - Google Patents

Compound propolis composition for treating cattle and sheep fascioliasis and preparation method thereof Download PDF

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Publication number
CN102670899A
CN102670899A CN201210144956XA CN201210144956A CN102670899A CN 102670899 A CN102670899 A CN 102670899A CN 201210144956X A CN201210144956X A CN 201210144956XA CN 201210144956 A CN201210144956 A CN 201210144956A CN 102670899 A CN102670899 A CN 102670899A
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parts
cattle
sheep
sulfur
propolis
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CN102670899B (en
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周庆福
刘文利
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Qingdao Lvman Bioengineering Co Ltd
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention relates to a compound propolis composition for treating cattle and sheep fascioliasis and a preparation method thereof. The compound propolis composition is prepared by mixing the following components in parts by weight: 15-35 parts of propolis, 15-45 parts of areca nut, 15-35 parts of sappan wood, 10-25 parts of sulfur, 15-35 parts of lightyellow sophora root, 15-45 parts of cyrtomium rhizome, 15-35 parts of chinaberry bark and root-bark, 15-35 parts of oriental waterplantain rhizome and 15-40 parts of liquoric root. The compound propolis composition has the beneficial effects of reasonable formula, easiness for preparing, environment friendliness, freeness from toxic and side effects, avoidance of medicament tolerance, no medicament residues, and very remarkable curative effect; and as proved by clinic, the compound propolis composition has a special treatment effect on cattle and sheep fascioliasis.

Description

Compound bee-glue composition of treatment cattle and sheep fascioliasis hepatica and preparation method thereof
Technical field
The present invention relates to a kind of compound bee-glue composition of treating the cattle and sheep fascioliasis hepatica and preparation method thereof, belong to the animal field of medicaments, particularly a kind of compound bee-glue composition that is specifically designed to treatment cattle and sheep fascioliasis hepatica and preparation method thereof.
Background technology
The cattle and sheep fascioliasis hepatica is that the distoma hepaticum by the Fasciolidae Fasciola parasitizes caused a kind of comparatively serious parasitic disease in the liver bile ducts of cattle and sheep.Primary disease can cause that cattle and sheep are acute, chronic hepatitis and cholangitis, and the systemic toxicity that occurs together simultaneously and malnutrition descend the cattle and sheep fertility performance, and young stock can cause large quantities of death, brings enormous economic loss to animal husbandry production.
At present, this disease can only be treated with anthelmintics such as nitre chlorine powder, the two dichloro powder of sulfur, Albendazole, carbon tetrachloride, in case produce drug resistance, this disease is difficult to cure; And also having drug residue, its livestock products influence health.This disease gives that pig industry and people are healthy to cause very big threat.
Therefore research and develop a kind of treat the cattle and sheep fascioliasis hepatica and have no side effect, drug residue free, the specific medicament that produces that has no drug resistance be one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point; A kind of reasonable recipe, preparation simple, have no side effect, have no drug resistance generation, drug residue free are provided, and effect obviously, is effectively treated compound bee-glue composition of cattle and sheep fascioliasis hepatica and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of compound bee-glue composition of treating the cattle and sheep fascioliasis hepatica, by following component by weight mixed preparing form: propolis 15-35 part, Semen Arecae 15-45 part, Lignum Sappan 15-35 part, sulfur 10-25 part, Radix Sophorae Flavescentis 15-35 part, Rhizoma Osmundae 15-45 part, Cortex Meliae 15-35 part, Rhizoma Alismatis 15-35 part, Radix Glycyrrhizae 15-40 part.
On the basis of such scheme, said various component optimum ratio amounts are: 25 parts of propolis, 30 parts of Semen Arecaes, 25 parts of Lignum Sappans, 15 parts in sulfur, 25 parts of Radix Sophorae Flavescentiss, 30 parts of Rhizoma Osmundae, 25 parts of Cortex Meliaees, 25 parts of Rhizoma Alismatis, 30 parts in Radix Glycyrrhizae.
A kind of method for preparing of treating the compound bee-glue composition of cattle and sheep fascioliasis hepatica, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Semen Arecae 15-45 part, Lignum Sappan 15-35 part, sulfur 10-25 part, Radix Sophorae Flavescentis 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Rhizoma Osmundae 15-45 part, Cortex Meliae 15-35 part, Rhizoma Alismatis 15-35 part, Radix Glycyrrhizae 15-40 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.
Lignum Sappan: sweet, salty, flat, GUIXIN, liver, spleen channel have the function of promoting the circulation of blood removing blood stasis with potent drugs, reducing swelling and alleviating pain; Cure mainly blood stasis, carbuncle etc.
Semen Arecae: bitter, hot, warm, return stomach, large intestine channel, have the function of anthelmintic, removing food stagnancy, circulation of qi promoting, diuretic; Cure mainly taeniasis, the impaction of rumen, dyspeptic abdominal distention, constipation, edema etc.
Sulfur: acid, temperature, poisonous, return kidney, large intestine channel, have and mend function fiery supporing yang, relieving constipation; Cure mainly yang deficiency constipation, deficiency and coldness asthma, scabies, carbuncle of yin nature malignant boil etc.
Radix Sophorae Flavescentis: bitter, puckery, cold, return liver, gallbladder, large intestine channel, the function that have heat clearing and damp drying, astringent therapy dysentery relieving, makes eye bright; Cure mainly damp-heat diarrhea, conjunctival congestion and swelling pain, nebula etc.
Rhizoma Osmundae: bitter, cold, return liver, stomach warp, have heat-clearing and toxic substances removing, cooling blood for hemostasis, anthelmintic function; Cure mainly epidemic disease flu, maculae caused by violent heat pathogen, sore swollen toxin, abdominal pain due to worm stagnation etc.
Cortex Meliae: bitter, cold, return stomach, liver, spleen channel, have the function of parasite killing, treatment tinea; Cure mainly abdominal pain due to worm stagnation, scabies etc.
Rhizoma Alismatis: sweet, light, cold, return kidney, urinary bladder channel, have the function of diuresis, clearing away damp-heat; Cure mainly dysuria, edema distension, diarrhea due to damp-heat etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
More than all flavor Chinese medicine according to the tcm theory compatible combination, to the paathogenic factor and the pathological change of cattle and sheep fascioliasis hepatica, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, and it is wide to draw materials, the curative effect highly significant.Theoretical theoretical according to motherland tradition Chinese veterinarian with the modern Chinese medicine pharmacology, optimize this nine kinds of medicines, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, specially good effect is arranged and has no side effect and drug resistance treating the cattle and sheep fascioliasis hepatica.And make livestock products reach nuisanceless requirement, satisfy the export standard of livestock products, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition of treating the cattle and sheep distoma hepaticum and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 150 parts of Semen Arecaes, 150 parts of Lignum Sappans, 100 parts in sulfur, 150 parts of Radix Sophorae Flavescentiss by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Rhizoma Osmundae, 150 parts of Cortex Meliaees, 150 parts of Rhizoma Alismatis, 150 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition of treating the cattle and sheep fascioliasis hepatica and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 300 parts of Semen Arecaes, 250 parts of Lignum Sappans, 150 parts in sulfur, 250 parts of Radix Sophorae Flavescentiss by weight, mix 5-10 minute to even;
(3) take by weighing 300 parts of Rhizoma Osmundae, 250 parts of Cortex Meliaees, 250 parts of Rhizoma Alismatis, 300 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition of treating the cattle and sheep fascioliasis hepatica and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis, 450 parts of Semen Arecaes, 350 parts of Lignum Sappans, 250 parts in sulfur, 350 parts of Radix Sophorae Flavescentiss by weight, mix 5-10 minute to even;
(3) take by weighing 450 parts of Rhizoma Osmundae, 350 parts of Cortex Meliaees, 350 parts of Rhizoma Alismatis, 400 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects for use 80-150 age in days, body weight at 20kg-40kg, and laboratory is diagnosed as the ill sheep of Hepar Caprae seu ovis fascioliasis.Ill sheep is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, 20 every group, 3 groups of feeding environments are identical, experimental period 7 days; The blank group is left intact, and the medicine matched group uses treatment with " liver fluke looses " by specification; Chinese medicine composition group of the present invention can be irritated the ill cattle and sheep of clothes with product of the present invention, and a day dose is the 50-100 gram present composition, every day 1 time, logotype 3-5 days; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment Hepar Caprae seu ovis fascioliasis:
Numbering Group Mortality rate % Cure rate % Symptom rate % is arranged during end
I The blank group 10.1 62.0 27.9
II Liver fluke looses and organizes 6.2 84.1 9.7
III Chinese medicine composition group of the present invention 3.4 92.0 4.6
This clinical effectiveness is through statistical analysis, and present composition group is loose to organize with liver fluke and compared significant difference (P<0.05) aspect the cure rate.
Above-mentioned detailed description of compound bee-glue composition of this treatment cattle and sheep fascioliasis hepatica and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. compound bee-glue composition of treating the cattle and sheep fascioliasis hepatica, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Semen Arecae 15-45 part, Lignum Sappan 15-35 part, sulfur 10-25 part, Radix Sophorae Flavescentis 15-35 part, Rhizoma Osmundae 15-45 part, Cortex Meliae 15-35 part, Rhizoma Alismatis 15-35 part, Radix Glycyrrhizae 15-40 part.
2. the compound bee-glue composition of treatment according to claim 1 cattle and sheep fascioliasis hepatica, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 30 parts of Semen Arecaes, 25 parts of Lignum Sappans, 15 parts in sulfur, 25 parts of Radix Sophorae Flavescentiss, 30 parts of Rhizoma Osmundae, 25 parts of Cortex Meliaees, 25 parts of Rhizoma Alismatis, 30 parts in Radix Glycyrrhizae.
3. the method for preparing of the compound bee-glue composition of a treatment according to claim 1 and 2 cattle and sheep fascioliasis hepatica is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Semen Arecae 15-45 part, Lignum Sappan 15-35 part, sulfur 10-25 part, Radix Sophorae Flavescentis 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Rhizoma Osmundae 15-45 part, Cortex Meliae 15-35 part, Rhizoma Alismatis 15-35 part, Radix Glycyrrhizae 15-40 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
CN201210144956.XA 2012-05-11 2012-05-11 Compound propolis composition for treating cattle and sheep fascioliasis and preparation method thereof Expired - Fee Related CN102670899B (en)

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN112691153A (en) * 2021-01-26 2021-04-23 辽宁农业职业技术学院 Traditional Chinese medicine composition for treating sheep liver leech and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN106039162A (en) * 2016-07-03 2016-10-26 张俊清 Mongolian medicine composition for treating bovine theileriosis

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CN1895369A (en) * 2006-06-12 2007-01-17 杨兴喜 Domestic Chinese-herb insect-repellent growth
CN101690767A (en) * 2009-09-29 2010-04-07 北京大北农动物保健科技有限责任公司 Compound pesticide for fishing and preparation method and application thereof

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Publication number Priority date Publication date Assignee Title
CN112691153A (en) * 2021-01-26 2021-04-23 辽宁农业职业技术学院 Traditional Chinese medicine composition for treating sheep liver leech and preparation method thereof

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