CN102488881B - Compound propolis composition for promoting pig growth and fattening as well as its preparation method - Google Patents

Abstract

Relating to the field of animal medicines, the invention provides a compound propolis composition for promoting pig growth and fattening as well as its preparation method. The composition and its preparation method in the invention are shown as the following: (1) respectively subjecting each component in a formula to superfine comminution and then to sieving through a sieve of 700 meshes; (2) weighing, by weight, 15-35 parts of propolis, 10-30 parts of gelsmium elegans, 10-45 parts of scorch-fried three immortals, and 15-40 parts of dried orange peels, and mixing them for 5-10min to a uniform state; (3) weighing, by weight, 15-35 parts of rhizoma atractylodis, 10-35 parts of betel nuts, 10-35 parts of licorice, 15-40 parts of dried ginger, and 15-35 parts of radix astragali, and mixing them for 5-10min to a uniform state; and (4) combining the compositions prepared in step (2) and (3), and continuing to mixing them for 10-15min to a uniform state, thus obtaining the compound propolis composition. The compound propolis composition of the invention has the advantages of reasonable formula, simple preparation, no toxic or side effect, no pollution, no medicine residue, no drug resistance, superfine comminution, high bioavailability, and very obvious curative effect. There is clinical evidence that the compound propolis composition in the invention has specific efficacy in promoting growth and fattening of livestock.

Description

A kind of compound bee-glue composition that promotes the pig growing and fattening and preparation method thereof

Technical field

The present invention relates to compound bee-glue composition promoted the pig growing and fattening and preparation method thereof, belong to the animal field of medicaments, particularly a kind of compound bee-glue composition that is specifically designed to promotion pig growing and fattening and preparation method thereof.

Background technology

Piglet or growing-finishing pigs slowly (being commonly called as cad pig) are relevant with many factors, mainly with weakness of the spleen and stomach, gastrointestinal retention, the disease of pig, to infect particularly parasitic infection etc. relevant, primary disease all can occur throughout the year, is one of principal disease of harm pig industry.

Western medical treatment mainly be take interpolation antimicrobial drug, vitamin, trace element etc. as main, and fattening effect is not very desirable; And the traditional Chinese medical science thinks that this disease treatment should adopt the principle of QI invigorating stomach invigorating, anthelmintic spleen invigorating, removing toxic substances removing food stagnancy.

This disease almost spreads all over the world all livestock culturings country, is widely distributed.At present, treat this disease the most frequently used be Chinese medicine and Western medicine, Chinese medicine is because its prescription is unreasonable or simple pulverizing the just, particle diameter is excessive, drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And in Western medicine, antimicrobial drug by force, easily produces the problems such as drug resistance and drug residue due to its toxic and side effects, clinical practice is very limited.

Therefore research and develop and a kind ofly promote that the having no side effect of pig growing and fattening, drug residue free, the specific medicament produced that has no drug resistance are one of this field scientific research technical staff new problems anxious to be resolved.

Summary of the invention

The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, successful, have no side effect, have no drug resistance and the compound bee-glue composition of effective promotion pig growing and fattening of drug residue and preparation method thereof.

Implementation of the present invention is as follows for achieving the above object: a kind of compound bee-glue composition that promotes the pig growing and fattening, by following component by weight mixed preparing form: propolis 15-35 part, Herba Gelsemii Elegantis 10-30 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-45 part, Pericarpium Citri Reticulatae 15-40 part, Rhizoma Atractylodis 15-35 part, Semen Arecae 10-35 part, Radix Glycyrrhizae 10-35 part, Rhizoma Zingiberis 15-40 part, Radix Astragali 15-35 part.

On the basis of such scheme, described various component optimum ratio amounts are: 25 parts of propolis, 20 parts of Herba Gelsemii Elegantis, 25 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 25 parts of Pericarpium Citri Reticulataes, 25 parts of Rhizoma Atractylodis, 20 parts of Semen Arecaes, 20 parts, Radix Glycyrrhizae, 25 parts of Rhizoma Zingiberiss, 25 parts of the Radixs Astragali.

A kind of preparation method that promotes the compound bee-glue composition of pig growing and fattening, carry out as follows:

(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;

(2) take by weight propolis 15-35 part, Herba Gelsemii Elegantis 10-30 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-45 part, Pericarpium Citri Reticulatae 15-40 part, mix 5-10 minute to even;

(3) take by weight Rhizoma Atractylodis 15-35 part, Semen Arecae 10-35 part, Radix Glycyrrhizae 10-35 part, Rhizoma Zingiberis 15-40 part, Radix Astragali 15-35 part, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

The medicinal property of each component is as follows:

Propolis: bitter, acrid, cold, return spleen, lung, stomach warp, there is anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.

JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata): sweet, flat, warm, GUIXIN, liver, kidney, large intestine channel, have invigorating the spleen and regulating the stomach, the stagnant function of soothing the liverization; Curing mainly food stagnation does not disappear, vomits and have loose bowels etc.

Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning.

Rhizoma Zingiberis: hot, hot, return spleen, stomach, kidney, the heart, lung meridian, have warming middle-JIAO cold, recuperating depleted YANG is promoted blood circulation, the function of dampness expectorant; Cure mainly that cold syndrome of the stomach lack of appetite, cold intestinal are had loose bowels, cold type of pain, extreme cold of the limbs, anemofrigid-damp arthralgia, phlegm retention breath with cough etc.

Pericarpium Citri Reticulatae: bitter, hot, warm, return lung, spleen channel, there is the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly poor appetite, stomachache, tripe is swollen, have loose bowels, productive cough due to phlegm-damp etc.

Herba Gelsemii Elegantis: acrid, bitter, warm, return lung, large intestine, heart channel, there is the function of stomach invigorating, parasite killing, dissipating blood stasis, pain relieving, counteracting toxic substances; Cure mainly dyspepsia, diarrhoea, malnutrition due to parasitic infestation, traumatic injury, eczema, scabies, sore swollen toxin etc.

Rhizoma Atractylodis: bitter, hot, warm, return spleen, stomach, Liver Channel, there is the function of drying damp and strengthening spleen, expelling wind and cold, improving eyesight; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold, nyctalopia etc.

The Radix Astragali: sweet, tepor, return spleen, lung meridian, there is the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.

Semen Arecae: bitter, hot, warm, return stomach, large intestine channel, there is the function of anthelmintic, removing food stagnancy, circulation of qi promoting, diuretic; Cure mainly parasitic disease, abdominal pain due to worm stagnation, the impaction of rumen, dyspeptic abdominal distention, constipation, edema etc.

Above all flavor Chinese medicine, according to the Chinese medical theory compatible combination, for paathogenic factor, clinical symptoms and the pathological change of unknown high fever of pigs, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease.

The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, have no side effect, no drug residue, have no drug resistance, and cost is low, draws materials wide, and micronizing, bioavailability are high, the curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory, optimize this nine flavors Chinese medicine, and make them according to optimum ratio, form pure Chinese powder medicine, clinical practice proves, to promoting the pig growing and fattening that specially good effect is arranged, and make its product meat reach nuisanceless requirement, meet the export standard of product, effectively guaranteed that people's is healthy.

The specific embodiment

Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:

Embodiment 1

A kind of compound bee-glue composition that promotes the pig growing and fattening and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;

(2) take by weight 150 parts of propolis, 100 parts of Herba Gelsemii Elegantis, 100 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 150 parts of Pericarpium Citri Reticulataes, mix 5-10 minute to even;

(3) take by weight 150 parts of Rhizoma Atractylodis, 100 parts of Semen Arecaes, 100 parts, Radix Glycyrrhizae, 150 parts of Rhizoma Zingiberiss, 150 parts of the Radixs Astragali, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 2

A kind of compound bee-glue composition that promotes the pig growing and fattening and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;

(2) take by weight 250 parts of propolis, 200 parts of Herba Gelsemii Elegantis, 250 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 250 parts of Pericarpium Citri Reticulataes, mix 5-10 minute to even;

(3) take by weight 250 parts of Rhizoma Atractylodis, 250 parts of Semen Arecaes, 250 parts, Radix Glycyrrhizae, 250 parts of Rhizoma Zingiberiss, 250 parts of the Radixs Astragali, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 3

A kind of compound bee-glue composition that promotes the pig growing and fattening and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;

(2) take by weight 350 parts of propolis, 300 parts of Herba Gelsemii Elegantis, 450 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 400 parts of Pericarpium Citri Reticulataes, mix 5-10 minute to even;

(3) take by weight 350 parts of Rhizoma Atractylodis, 350 parts of Semen Arecaes, 350 parts, Radix Glycyrrhizae, 400 parts of Rhizoma Zingiberiss, 350 parts of the Radixs Astragali, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Clinical trial:

By the ill pig of product feeding of the present invention etc., a day dose is: by the every 100g of the present invention, spice 250kg feeds, and drinking-water 460kg, every day 1-2 time, be used in conjunction 7-10 day; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.

Table is field application (30 days experimental periods) situation contrast that the present invention and other medicines promote the pig growing and fattening:

Numbering	Group	Average just starting weight (kg)	Rate of body weight gain %	The average whole story heavy (kg)
					I	The blank group	10.5	10.5	11.6
II	The powder for improving appetite group	10.8	66.7	18.0
					III	Present composition group	10.7	80.3	19.3

This clinical effectiveness statistical analysis, present composition group is being compared difference extremely significantly (P<0.01) with the powder for improving appetite group aspect rate of body weight gain.

Above-mentioned detailed description of compound bee-glue composition of this promotion pig growing and fattening and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.

Claims (3)

1. a compound bee-glue composition that promotes the pig growing and fattening, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Herba Gelsemii Elegantis 10-30 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-45 part, Pericarpium Citri Reticulatae 15-40 part, Rhizoma Atractylodis 15-35 part, Semen Arecae 10-35 part, Radix Glycyrrhizae 10-35 part, Rhizoma Zingiberis 15-40 part, Radix Astragali 15-35 part.

2. the compound bee-glue composition of promotion according to claim 1 pig growing and fattening, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 20 parts of Herba Gelsemii Elegantis, 25 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 25 parts of Pericarpium Citri Reticulataes, 25 parts of Rhizoma Atractylodis, 20 parts of Semen Arecaes, 20 parts, Radix Glycyrrhizae, 25 parts of Rhizoma Zingiberiss, 25 parts of the Radixs Astragali.

3. the preparation method of the compound bee-glue composition of a promotion according to claim 1 pig growing and fattening is characterized in that carrying out as follows:

(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;

(2) take by weight propolis 15-35 part, Herba Gelsemii Elegantis 10-30 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-45 part, Pericarpium Citri Reticulatae 15-40 part, mix 5-10 minute to even;

(3) take by weight Rhizoma Atractylodis 15-35 part, Semen Arecae 10-35 part, Radix Glycyrrhizae 10-35 part, Rhizoma Zingiberis 15-40 part, Radix Astragali 15-35 part, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.