CN103599504A - Pure traditional Chinese medicine composition for treating poultry gout and preparation method thereof - Google Patents
Pure traditional Chinese medicine composition for treating poultry gout and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pure traditional Chinese medicine composition for treating poultry gout. A preparation method of the pure traditional Chinese medicine composition comprises the following steps: (1) respectively carrying out superfine grinding on all components in a formula, and then sieving by using a 700-mesh sieve; (2) weighing 15-35 parts of ephedra, 15-35 parts of dried ginger, 15-25 parts of cassia twig and 15-35 parts of monkshood, and uniformly mixing for 5-10 minutes; (3) weighing 15-35 parts of dried orange peel, 25-35 parts of liquorice, 15-35 parts of radix astragali, 15-25 parts of bighead atractylodes rhizome, 15-35 parts of root of fangji, and uniformly mixing for 5-10 minutes; and (4) combining compositions prepared in the step (1), the step (2) and the step (3), and continuously and uniformly mixing for 10-15 minutes. The pure traditional Chinese medicine composition has the beneficial effects that the pure traditional Chinese medicine composition is reasonable in formula, simple to prepare and pollution-free and has a very obvious curative effect, and the clinical applications prove that the pure traditional Chinese medicine composition has a special effect on the treatment of the poultry gout.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of gout in poultry and preparation method thereof, belong to animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to treatment gout in poultry and preparation method thereof.
Background technology
Gout in poultry also claims uratohistechia, is due to protein metabolism disturbance, a large amount of urate deposition around joint, cartilaginous tissue, internal organs and other stroma and the metabolic disease that causes.Take clinically arthroncus, limping, body is weak and diarrhoea is feature.This disease all can occur throughout the year, and mortality rate is in 10% left and right, and the poultry growth promoter of recovering is obstructed, and the price of deed declines, and Abwehrkraft des Koepers reduces, and easily suffers from Other diseases, very large to the harm of poultry.
At present, treat this disease the most frequently used be various ntipyretic analgesic medicines and allopurinol etc., prolonged application can cause poultry immunity function to reduce, cause the toxic and side effects such as intestinal bleeding, and drug residue in animal body, its product does not reach nuisanceless requirement, has affected the outlet of poultry product and people's health.
Therefore research and develop a kind of treat gout in poultry and have no side effect, the specific medicament of drug residue free is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, effectively treat pure Chinese medicine composition of gout in poultry and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of gout in poultry, by following component by weight mixed preparing form: Herba Ephedrae 15-35 part, Rhizoma Zingiberis Recens 15-35 part, Ramulus Cinnamomi 15-25 part, Radix Aconiti Lateralis Preparata 15-35 part, Pericarpium Citri Reticulatae 15-35 part, Radix Glycyrrhizae 25-35 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Stephaniae Tetrandrae 15-35 part.
Described various component optimum ratio amount is: 25 parts, Herba Ephedrae, 25 parts, Rhizoma Zingiberis Recens, 20 parts of Ramulus Cinnamomi, 25 parts of Radix Aconiti Lateralis Preparatas, 25 parts of Pericarpium Citri Reticulataes, 30 parts, Radix Glycyrrhizae, 25 parts of the Radixs Astragali, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts of Radixs Stephaniae Tetrandrae.
Treat a preparation method for the pure Chinese medicine composition of gout in poultry, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Herba Ephedrae 15-35 part, Rhizoma Zingiberis Recens 15-35 part, Ramulus Cinnamomi 15-25 part, Radix Aconiti Lateralis Preparata 15-35 part, mix 5-10 minute to even;
(3) take by weight Pericarpium Citri Reticulatae 15-35 part, Radix Glycyrrhizae 25-35 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Stephaniae Tetrandrae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Herba Ephedrae: micro-hardship, temperature, pungent, return lung, urinary bladder channel, there is the function of the cold expelling that induces sweat, depressed lung-energy dispersing, inducing diuresis to remove edema; Cure mainly affection of exogenous wind-cold, cough, asthma, edema etc.
Rhizoma Zingiberis Recens: warm, pungent, return lung, urinary bladder channel, there is the function of the cold expelling that induces sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing; Cure mainly for anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough etc.
Ramulus Cinnamomi: sweet, pungent, warm, return lung, the heart, urinary bladder channel, there is the function of diaphoresis expelling pathogenic factors from muscles, warming the meridian for promoting the flow of YANG QI; Cure mainly wind and cold sign, arthralgia, retention of water-damp etc.
Radix Aconiti Lateralis Preparata: sweet, pungent, hot, return spleen, the heart, kidney channel, there is warming middle-JIAO except the function of cold, recuperating depleted YANG and rescuing the patient from collapse, expelling wind and removing dampness; Cure mainly that profuse sweating, YANG-depletion, extreme cold of the limbs, rheumatism, enterospasm, cold intestinal are had loose bowels, anemofrigid-damp arthralgia etc.
Pericarpium Citri Reticulatae: bitter, pungent, warm, return lung, spleen channel, there is the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly poor appetite, stomachache, tripe is swollen, have loose bowels, productive cough due to phlegm-damp etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
The Radix Astragali: sweet, tepor, return spleen, lung meridian, there is the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, return spleen, stomach warp, there is the function of invigorating the spleen and replenishing QI, dampness diuretic; Cure mainly diarrhea due to hypofunction of the spleen, edema etc.
Radix Stephaniae Tetrandrae: pungent, sweet, warm, return liver, spleen, urinary bladder channel, there is inducing diaphoresis to dispel wind, win function wet, spasmolytic; Cure mainly affection of exogenous wind-cold, anemofrigid-damp arthralgia, rubella pruritus, tetanus etc.
All taste Chinese medicine is according to tcm theory compatible combination, for paathogenic factor and the pathological change of gout in poultry, mainly according to the rule for the treatment of performance therapeutical effect of tonifying Qi and lifting yang, relieving the exterior syndrome with drugs of pungent in flavor and warm in nature, warming the interior cold expelling above.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, draws materials wide, curative effect highly significant.According to the tradition Chinese veterinarian of motherland, theoretical and modern Chinese medicine pharmacology theory, optimizes this nine kinds of medicines, and makes them according to optimum ratio, form pure Chinese powder medicine, and clinical practice proves that treatment gout in poultry is had specially good effect and had no side effect and drug resistance.And make poultry product reach nuisanceless requirement, meet the export standard of poultry product, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of gout in poultry and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 150 parts, Herba Ephedrae, 150 parts, Rhizoma Zingiberis Recens, 150 parts of Ramulus Cinnamomi, 150 parts of Radix Aconiti Lateralis Preparatas, mix 5-10 minute to even;
(3) take by weight 150 parts of Pericarpium Citri Reticulataes, 250 parts, Radix Glycyrrhizae, 150 parts of the Radixs Astragali, 150 parts of the Rhizoma Atractylodis Macrocephalaes, 150 parts of Radixs Stephaniae Tetrandrae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of gout in poultry and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 250 parts, Herba Ephedrae, 250 parts, Rhizoma Zingiberis Recens, 200 parts of Ramulus Cinnamomi, 250 parts of Radix Aconiti Lateralis Preparatas, mix 5-10 minute to even;
(3) take by weight 250 parts of Pericarpium Citri Reticulataes, 300 parts, Radix Glycyrrhizae, 250 parts of the Radixs Astragali, 200 parts of the Rhizoma Atractylodis Macrocephalaes, 250 parts of Radixs Stephaniae Tetrandrae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of gout in poultry and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 350 parts, Herba Ephedrae, 350 parts, Rhizoma Zingiberis Recens, 250 parts of Ramulus Cinnamomi, 350 parts of Radix Aconiti Lateralis Preparatas, mix 5-10 minute to even;
(3) take by weight 350 parts of Pericarpium Citri Reticulataes, 350 parts, Radix Glycyrrhizae, 350 parts of the Radixs Astragali, 250 parts of the Rhizoma Atractylodis Macrocephalaes, 350 parts of Radixs Stephaniae Tetrandrae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
Clinical experiment animal selects 22 ages in days, body weight at 1.0kg-1.1kg, and Laboratory Diagnosed is that the ill broiler of chicken gout is tested.Ill chicken isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 100 every group, 3 groups of feeding environments are identical, and experimental period is carried out 5 days altogether; Blank group is left intact, and medicine matched group is used treatment by institute's control drug by its description; Present composition group is product of the present invention (the prepared compositions of the embodiment of the present invention 1) the ill broiler of feeding, and a day dose is: 400 kilograms are fed or drunk water to 200 kilograms of every 100 grams of present composition spices, every day 1-2 time; After oral, by gastrointestinal absorption, reach the object for the treatment of disease.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result (testing the 5th day) when following table is experiment end.
Table is the field applicable cases contrast of product of the present invention and other medicines treatment gout in poultry:
| Numbering | Group | Mortality rate % | Cure rate % | During end, there is symptom rate % |
| I | Blank group | 12 | 70 | 18 |
| II | The gout group of faling apart | 8 | 80 | 12 |
| III | Chinese medicine composition group of the present invention | 5 | 88 | 7 |
This clinical effectiveness statistical analysis, present composition group is being compared difference extremely significantly (P<0.01) with the loose group of gout aspect cure rate.
Safety testing:
Choose 60 of the healthy broiler of 20 ages in days, according to 10 times of spices of the made Chinese medicine composition recommended dose of the embodiment of the present invention 1 or drink water 5 days, during medication, healthy chicken is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and body weight increases that to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of pure Chinese medicine composition of this treatment gout in poultry and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (3)
1. treat a pure Chinese medicine composition for gout in poultry, it is characterized in that by following component by weight mixed preparing form: Herba Ephedrae 15-35 part, Rhizoma Zingiberis Recens 15-35 part, Ramulus Cinnamomi 15-25 part, Radix Aconiti Lateralis Preparata 15-35 part, Pericarpium Citri Reticulatae 15-35 part, Radix Glycyrrhizae 25-35 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Stephaniae Tetrandrae 15-35 part.
2. the pure Chinese medicine composition for the treatment of gout in poultry according to claim 1, is characterized in that described various component optimum ratio amount is: 25 parts, Herba Ephedrae, 25 parts, Rhizoma Zingiberis Recens, 20 parts of Ramulus Cinnamomi, 25 parts of Radix Aconiti Lateralis Preparatas, 25 parts of Pericarpium Citri Reticulataes, 30 parts, Radix Glycyrrhizae, 25 parts of the Radixs Astragali, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts of Radixs Stephaniae Tetrandrae.
3. a preparation method for the pure Chinese medicine composition for the treatment of gout in poultry according to claim 1 and 2, is characterized in that carrying out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Herba Ephedrae 15-35 part, Rhizoma Zingiberis Recens 15-35 part, Ramulus Cinnamomi 15-25 part, Radix Aconiti Lateralis Preparata 15-35 part, mix 5-10 minute to even;
(3) take by weight Pericarpium Citri Reticulatae 15-35 part, Radix Glycyrrhizae 25-35 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Radix Stephaniae Tetrandrae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN104435261A (en) * | 2014-12-24 | 2015-03-25 | 重庆金邦动物药业有限公司 | Preparation method of traditional Chinese medicine compound medicine for treating poultry gout |
| CN104523928A (en) * | 2014-12-24 | 2015-04-22 | 重庆金邦动物药业有限公司 | Compound traditional Chinese medicine for treating poultry gout |
| CN104905034A (en) * | 2015-05-25 | 2015-09-16 | 袁春梅 | Compound feed for chicken and preparation method of compound feed for chicken |
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| CN105326927A (en) * | 2015-12-15 | 2016-02-17 | 天农大（天津）生物科技有限公司 | Traditional Chinese medicine composition for treating goose gout and preparing method thereof |
| CN107551009A (en) * | 2017-10-24 | 2018-01-09 | 丹东瑞丰动物药业有限责任公司 | A kind of herbal medicine for treating gout of poultry and preparation method thereof |
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| CN104435261A (en) * | 2014-12-24 | 2015-03-25 | 重庆金邦动物药业有限公司 | Preparation method of traditional Chinese medicine compound medicine for treating poultry gout |
| CN104523928A (en) * | 2014-12-24 | 2015-04-22 | 重庆金邦动物药业有限公司 | Compound traditional Chinese medicine for treating poultry gout |
| CN104435261B (en) * | 2014-12-24 | 2017-06-13 | 重庆金邦动物药业有限公司 | A kind of preparation method of the traditional Chinese compound medicine for treating gout in poultry |
| CN104905034A (en) * | 2015-05-25 | 2015-09-16 | 袁春梅 | Compound feed for chicken and preparation method of compound feed for chicken |
| CN105012930A (en) * | 2015-08-25 | 2015-11-04 | 刘杰 | Traditional Chinese medicine for treating gout |
| CN105326927A (en) * | 2015-12-15 | 2016-02-17 | 天农大（天津）生物科技有限公司 | Traditional Chinese medicine composition for treating goose gout and preparing method thereof |
| CN107551009A (en) * | 2017-10-24 | 2018-01-09 | 丹东瑞丰动物药业有限责任公司 | A kind of herbal medicine for treating gout of poultry and preparation method thereof |
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| CN103599504B (en) | 2016-08-17 |
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