CN103520516A - Pure traditional Chinese medicine composition for treatment of piglet yellow-white dysentery and preparation method thereof - Google Patents
Pure traditional Chinese medicine composition for treatment of piglet yellow-white dysentery and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pure traditional Chinese medicine composition for treatment of piglet yellow-white dysentery, and a specific preparation method of the pure traditional Chinese medicine composition comprises the following steps: (1) all components in the prescription are respectively superfinely crushed, then passes through a 700 mesh sieve, (2) weighing, by weight, 15-45 parts of dried orange peel, 15-45 parts of haw, 15-45 parts of radix astragali, 15-35 parts of dendrobe and 15-35 parts of bighead atractylodes rhizome, mixing for 5-10 minutes to even; (3) weighing, by weight, 15-35 parts of licorice, 15-35 parts of biota orientalis, 15-35 parts of carbonized hair, 15-45 parts of folium artemisiae argyi and 15-25 parts fennel, mixing for 5-10 minutes to even; (4) merging compositions prepared by the step (2) and (3), continuing to mix for 10-15 minutes to uniform. The beneficial effects of the pure traditional Chinese medicine composition are that: the prescription is reasonable, the preparation is simple, the pure traditional Chinese medicine composition has no toxic and side effect, no drug residue and no drug resistance, is superfinely crushed, and has high bioavailability and obvious curative effects, and clinic proofs that the pure traditional Chinese medicine composition has specific effects on treatment of the piglet yellow-white dysentery.
Description
Technical field
The present invention relates to Chinese medicine composition for the treatment of poultry and preparation method thereof, particularly a kind of pure Chinese medicine composition that is specifically designed to treatment yellow and white dysentery of piglet and preparation method thereof.
Background technology
Yellow scour of piglet, piglet pujos blancos are that a kind of common alimentary infection being caused by escherichia coli is sick, and take clinically diarrhoea, row's yellow or yellow-white feces is feature, or take ash discharge white, smell as of rotten fish, paste shape loose stool is feature, very large to the harm of piglet.
The pathogen of primary disease is escherichia coli, and this disease spreads all over more than 100 countries of five continents, is widely distributed.At present, treat this disease the most frequently used be various antibacterials, as oxytetracycline, chloromycetin, penicillin, streptomycin, quinolinones etc.; Due to the prolonged and repeated use of antibacterials, cause this pathogenic microorganism to produce drug resistance to medicine, reduced curative effect, and drug residue is in animal body, its meat does not reach nuisanceless requirement, has affected the outlet of livestock products and people's health.
Therefore researching and developing a kind of specific medicament for the treatment of yellow and white dysentery of piglet is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, effectively treat pure Chinese medicine composition of yellow and white dysentery of piglet and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of yellow and white dysentery of piglet, by following component by weight mixed preparing form: Pericarpium Citri Reticulatae 15-45 part, Fructus Crataegi 15-45 part, Radix Astragali 15-45 part, Herba Dendrobii 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part, Radix Glycyrrhizae 15-35 part, Cacumen Platycladi 15-35 part, Crinis Carbonisatus 15-35 part, Folium Artemisiae Argyi 15-45 part, Fructus Foeniculi 15-25 part.
Described various component optimum ratio amount is: 30 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Crataegis, 30 parts of the Radixs Astragali, 25 parts of Herba Dendrobiis, 25 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts, Radix Glycyrrhizae, 25 parts of Cacumen Platycladis, 25 parts of Crinis Carbonisatus, 30 parts of Folium Artemisiae Argyis, 20 parts of Fructus Foeniculi.
A preparation method for the pure Chinese medicine composition of yellow and white dysentery of piglet, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Pericarpium Citri Reticulatae 15-45 part, Fructus Crataegi 15-45 part, Radix Astragali 15-45 part, Herba Dendrobii 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part, mix 5-10 minute to even;
(3) take by weight Radix Glycyrrhizae 15-35 part, Cacumen Platycladi 15-35 part, Crinis Carbonisatus 15-35 part, Folium Artemisiae Argyi 15-45 part, Fructus Foeniculi 15-25 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Pericarpium Citri Reticulatae: bitter, pungent, warm, return lung, spleen channel, there is the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly poor appetite, stomachache, tripe is swollen, have loose bowels, productive cough due to phlegm-damp etc.
Fructus Crataegi: sour, sweet, tepor, return stomach, spleen, Liver Channel, there is the function of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis; Cure mainly dyspeptic abdominal flatulence, dyspepsia, prolonged lochia etc.
The Radix Astragali: sweet, tepor, return spleen, lung meridian, there is the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
Herba Dendrobii: sweet, warm, return spleen, lung meridian, there is the function of Yin-nourishing and body fluid promoting, heat clearing away nourishing the stomach; Cure mainly consumption of body fluid caused by febrile disease, spontaneous perspiration, thirst and liking drink etc.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, return spleen, stomach warp, there is the function of invigorating the spleen and replenishing QI, dampness diuretic; Cure mainly diarrhea due to hypofunction of the spleen, edema etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Cacumen Platycladi: bitter, cold, puckery, return spleen, lung, spleen channel, there is the function of cooling blood for hemostasis, reducing swelling and alleviating pain, clearing away lung-heat to relieve cough; Cure mainly hemoptysis, epistaxis, have blood in stool, hematuria, metrorrhagia, swelling and pain due to blood stasis, cough due to lung-heat etc.
Blood She charcoal: bitter, warm, return spleen, lung, spleen channel, there is the function that skin ulcer is closed in hemostasis, granulation promoting; Cure mainly various hemorrhage etc.
Folium Artemisiae Argyi: acrid, bitter, warm, return liver,kidney,spleen warp, there is the function of dispersing cold for relieving pain, warming the meridian for stopping bleeding; Cure mainly anemofrigid-damp arthralgia, tripe abdomen cold type of pain etc.
Fructus Foeniculi: pungent, sweet, warm, return liver,kidney,spleen warp, there is the function of cold-dispelling pain-relieving, regulating qi-flowing for harmonizing stomach; Cure mainly cold stagnant stomachache, tripe distention and fullness in the abdomen, Deficiency and coldness of spleen and stomach, enterospasm, have loose bowels, tremble with fear and hinder waist hip etc.
All taste Chinese medicine, according to tcm theory compatible combination, for the clinical symptoms of yellow and white dysentery of piglet, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease above.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition no drug residue, the generation that has no drug resistance, cost is low, draws materials wide, curative effect highly significant.Adopt molecular pharmacology and the Chinese veterinarian of motherland determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs method, optimize this ten kinds of medicines, and make them according to optimum ratio, form pure Chinese powder medicine, clinical practice proves that treatment yellow scour of piglet, piglet pujos blancos are had to specially good effect.And make livestock products meat reach nuisanceless requirement, meet the export standard of livestock products, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of yellow and white dysentery of piglet and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 150 parts of Pericarpium Citri Reticulataes, 150 parts of Fructus Crataegis, 150 parts of the Radixs Astragali, 150 parts of Herba Dendrobiis, 150 parts of the Rhizoma Atractylodis Macrocephalaes, mix 5-10 minute to even;
(3) take by weight 150 parts, Radix Glycyrrhizae, 150 parts of Cacumen Platycladis, 150 parts of Crinis Carbonisatus, 150 parts of Folium Artemisiae Argyis, 150 parts of Fructus Foeniculi, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of yellow and white dysentery of piglet and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 300 parts of Pericarpium Citri Reticulataes, 300 parts of Fructus Crataegis, 300 parts of the Radixs Astragali, 250 parts of Herba Dendrobiis, 250 parts of the Rhizoma Atractylodis Macrocephalaes, mix 5-10 minute to even;
(3) take by weight 250 parts, Radix Glycyrrhizae, 250 parts of Cacumen Platycladis, 250 parts of Crinis Carbonisatus, 300 parts of Folium Artemisiae Argyis, 200 parts of Fructus Foeniculi, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of yellow and white dysentery of piglet and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 450 parts of Pericarpium Citri Reticulataes, 450 parts of Fructus Crataegis, 450 parts of the Radixs Astragali, 350 parts of Herba Dendrobiis, 350 parts of the Rhizoma Atractylodis Macrocephalaes, mix 5-10 minute to even;
(3) take by weight 350 parts, Radix Glycyrrhizae, 350 parts of Cacumen Platycladis, 350 parts of Crinis Carbonisatus, 450 parts of Folium Artemisiae Argyis, 250 parts of Fructus Foeniculi, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
Clinical experiment animal selects 10-25 age in days, body weight at 6.5kg-15kg, and Laboratory Diagnosed is the ill piglet of piglet pujos blancos and yellow scour of piglet.Ill piglet isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 30 every group, 3 groups of feeding environments are identical, and experiment is carried out 7 days altogether; Blank group is left intact, and medicine matched group is used treatment by institute's control drug by its description; Chinese medicine composition group of the present invention can be by product of the present invention (the prepared compositions of the embodiment of the present invention 2) the ill piglet of feeding etc., and a day dose is: by per kilogram of body weight 2g-4g, spice is fed, and every day 1-2 time, is used in conjunction 3-5 day; After oral, by gastrointestinal, absorb the object that reaches treatment disease.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result (testing the 7th day) when following table is experiment end.
Piglet pujos blancos efficacy assessment standard:
Cure: spirit is normal, the drinking-water of searching for food is normal, and feces is normal, and bouncing cuts open inspection intestinal etc. normal.
During end, there is symptom: clinical symptoms is not improved and even increased the weight of.
Table 1 is the field applicable cases contrast of the present invention and other medicines treatment yellow scour of piglet:
| Numbering | Group | Mortality rate % | Cure rate % | During end, there is symptom rate % |
| I | Blank group | 20 | 23.3 | 56.7 |
| II | The yellow scour of piglet group of faling apart | 6.7 | 76.6 | 16.7 |
| III | Chinese medicine composition group of the present invention | 6.7 | 86.6 | 6.7 |
Clinical effectiveness statistical analysis, present composition group is compared difference extremely significantly (P < 0.01) with the loose group of yellow scour of piglet.
Yellow scour of piglet efficacy assessment standard:
Cure: spirit is normal, the drinking-water of searching for food is normal, and feces is normal, and bouncing cuts open inspection intestinal etc. normal.
During end, there is symptom: clinical symptoms is not improved and even increased the weight of.
Table 2 is field applicable cases contrasts of the present invention and other medicines treatment piglet pujos blancos:
| Numbering | Group | Mortality rate % | Cure rate % | During end, there is symptom rate % |
| I | Blank group | 20 | 23.3 | 56.7 |
| II | The piglet pujos blancos group of faling apart | 6.7 | 73.3 | 20 |
| III | Chinese medicine composition group of the present invention | 6.7 | 83.3 | 10 |
This clinical effectiveness statistical analysis, present composition group is compared difference extremely significantly (P < 0.01) with the loose group of piglet pujos blancos.
Safety testing:
Choose 10 of 70 age in days health pig, 5 times of spices according to the made compositions recommended dose of the embodiment of the present invention 2 are fed 10 days, during medication, health pig is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and body weight increases that to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of pure Chinese medicine composition of this treatment yellow and white dysentery of piglet and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (3)
1. treat a pure Chinese medicine composition for yellow and white dysentery of piglet, it is characterized in that by following component by weight mixed preparing form: Pericarpium Citri Reticulatae 15-45 part, Fructus Crataegi 15-45 part, Radix Astragali 15-45 part, Herba Dendrobii 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part, Radix Glycyrrhizae 15-35 part, Cacumen Platycladi 15-35 part, Crinis Carbonisatus 15-35 part, Folium Artemisiae Argyi 15-45 part, Fructus Foeniculi 15-25 part.
2. the pure Chinese medicine composition for the treatment of yellow and white dysentery of piglet according to claim 1, is characterized in that described various component optimum ratio amount is: 30 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Crataegis, 30 parts of the Radixs Astragali, 25 parts of Herba Dendrobiis, 25 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts, Radix Glycyrrhizae, 25 parts of Cacumen Platycladis, 25 parts of Crinis Carbonisatus, 30 parts of Folium Artemisiae Argyis, 20 parts of Fructus Foeniculi.
3. a preparation method for the pure Chinese medicine composition for the treatment of yellow and white dysentery of piglet according to claim 1 and 2, is characterized in that carrying out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Pericarpium Citri Reticulatae 15-45 part, Fructus Crataegi 15-45 part, Radix Astragali 15-45 part, Herba Dendrobii 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part, mix 5-10 minute to even;
(3) take by weight Radix Glycyrrhizae 15-35 part, Cacumen Platycladi 15-35 part, Crinis Carbonisatus 15-35 part, Folium Artemisiae Argyi 15-45 part, Fructus Foeniculi 15-25 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107737171A (en) * | 2017-09-18 | 2018-02-27 | 颍上庆丰农牧发展有限公司 | It is a kind of to be used to treat parenteral solution of the black pig piglet yellow scour in Anhui north and preparation method thereof |
| CN113069491A (en) * | 2021-04-21 | 2021-07-06 | 怀化职业技术学院 | Composition for preventing and treating pig digestive tract diseases and preparation method and application thereof |
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| CN102670770A (en) * | 2012-05-07 | 2012-09-19 | 青岛绿曼生物工程有限公司 | Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102670770A (en) * | 2012-05-07 | 2012-09-19 | 青岛绿曼生物工程有限公司 | Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 胡元亮等: "《新编中兽医验方与妙用》", 31 March 2009 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107737171A (en) * | 2017-09-18 | 2018-02-27 | 颍上庆丰农牧发展有限公司 | It is a kind of to be used to treat parenteral solution of the black pig piglet yellow scour in Anhui north and preparation method thereof |
| CN113069491A (en) * | 2021-04-21 | 2021-07-06 | 怀化职业技术学院 | Composition for preventing and treating pig digestive tract diseases and preparation method and application thereof |
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