CN102670770A - Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof - Google Patents

Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof Download PDF

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Publication number
CN102670770A
CN102670770A CN2012101372568A CN201210137256A CN102670770A CN 102670770 A CN102670770 A CN 102670770A CN 2012101372568 A CN2012101372568 A CN 2012101372568A CN 201210137256 A CN201210137256 A CN 201210137256A CN 102670770 A CN102670770 A CN 102670770A
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parts
weight
pure chinese
propolis
medicinal composition
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CN102670770B (en
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周庆福
刘文利
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Qingdao Lvman Bioengineering Co Ltd
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention discloses a compound propolis pure Chinese medicinal composition for treating white scour of piglets. The compound propolis pure Chinese medicinal composition is prepared by mixing the following components in parts by weight: 10-35 parts of Chinese atractylodes, 10-35 parts of lightyellow sophora root, 10-35 parts of propolis, 15-25 parts of Chinese pulsatilla root, 15-25 parts of coptis root, 20-40 parts of fructus crataegi and 15-35 parts of ash bark. A preparation method of the compound propolis pure Chinese medicinal composition comprises the following steps of: (1) finely grinding each component in a composition, and sieving with a 700-mesh sieve; (2) weighing 10-35 parts by weight of Chinese atractylodes, 10-35 parts by weight of lightyellow sophora root and 10-35 parts by weight of propolis, and mixing for 5-10 minutes to a uniform state; (3) weighing 15-25 parts by weight of Chinese pulsatilla root, 15-25 parts by weight of coptis root, 20-40 parts by weight of fructus crataegi and 15-35 parts by weight of ash bark, and mixing for 5-10 minutes to a uniform state; and (4) combining compositions prepared in the steps (2) and (3), and continually mixing for 10-15 minutes to a uniform state. The compound propolis pure Chinese medicinal composition has the beneficial effects of reasonable composition, easiness for preparing, freeness from toxic and side effects, no medicament residues, and very remarkable curative effect; and as proved by clinic, the compound propolis pure Chinese medicinal composition has a special treatment effect on white scour of piglets.

Description

A kind of pure Chinese medicine composition of compound bee-glue of treating piglet pujos blancos and preparation method thereof
Technical field
The present invention relates to pure Chinese medicine composition of a kind of compound bee-glue and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition of compound bee-glue that is specifically designed to the treatment piglet pujos blancos and preparation method thereof.
Background technology
Piglet pujos blancos is that a kind of common alimentary infection that is caused by escherichia coli is sick, is characteristic with diarrhoea, ash discharge white, stench, paste shape loose stool clinically, and sickness rate is between 30%-80%, and mortality rate is more than 10%, and is very big to the harm of piglet.
The pathogen of primary disease is escherichia coli, and this disease spreads all over more than 100 countries of five continents, distributes very extensively.At present, treat this disease the most frequently used be various antibacterials, like oxytetracycline, chloromycetin, penicillin, streptomycin, quinolinones etc.; Because the prolonged and repeated use of antibacterials causes this pathogenic microorganism that medicine has been produced drug resistance, reduced curative effect, and drug residue in animal body, its meat does not reach nuisanceless requirement, has influenced the outlet of livestock products and people's health.
Therefore researching and developing a kind of specific medicament of treating piglet pujos blancos is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, effect obviously, have no side effect, drug residue free, effectively treat pure Chinese medicine composition of compound bee-glue of piglet pujos blancos and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of pure Chinese medicine composition of compound bee-glue of treating piglet pujos blancos, by following component by weight mixed preparing form: Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part, Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part.
On the basis of such scheme, said various component optimum ratio amounts are: 20 parts of Rhizoma Atractylodis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of propolis, 20 parts of the Radix Pulsatillaes, 20 parts of Rhizoma Coptidis, 30 parts of Fructus Crataegis, 25 parts of Cortex Fraxinis.
A kind of method for preparing of treating the pure Chinese medicine composition of compound bee-glue of piglet pujos blancos, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa etc.
Rhizoma Atractylodis: hot, bitter, warm, return spleen, stomach, Liver Channel, the function that have drying damp and strengthening spleen, expelling wind and cold, makes eye bright; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold etc.
Fructus Crataegi: sour, sweet, tepor, return stomach, spleen, Liver Channel, have the function of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis; Cure mainly dyspeptic abdominal flatulence, dyspepsia, prolonged lochia etc.
Radix Sophorae Flavescentis: Radix Sophorae Flavescentis: bitter, cold, return liver, the heart, stomach, large intestine, urinary bladder channel, have that heat clearing and damp drying, parasite killing go to amass, the function of diuretic; Cure mainly damp-heat dysentery etc.
Rhizoma Coptidis: bitter, cold, return spleen, stomach, large intestine, gallbladder, heart channel, have the function of heat clearing and damp drying, eliminating fire and detoxication; Cure mainly damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder etc.
The Radix Pulsatillae: bitter, cold, return stomach, large intestine channel, have the function of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Cure mainly toxic-heat and blood stasis, damp and hot intestinal Huang etc.
Cortex Fraxini: bitter, puckery, cold, return liver, gallbladder, large intestine channel, the function that have heat clearing and damp drying, astringent therapy dysentery relieving, makes eye bright; Cure mainly damp-heat diarrhea, conjunctival congestion and swelling pain, nebula etc.
More than all flavor Chinese medicine according to the tcm theory compatible combination, to the pathogenic microorganism and the clinical symptoms of piglet pujos blancos, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and the generation that has no drug resistance, cost is low, and it is wide to draw materials, the curative effect highly significant.Adopt pharmacology and the Chinese veterinarian of motherland determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs method, optimize this seven kinds of medicines, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves that the treatment piglet pujos blancos is had specially good effect.And make the livestock products meat reach nuisanceless requirement, satisfy the export standard of livestock products, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of pure Chinese medicine composition of compound bee-glue of treating piglet pujos blancos and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 100 parts of Rhizoma Atractylodis, 100 parts of Radix Sophorae Flavescentiss, 100 parts of propolis by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of the Radix Pulsatillaes, 150 parts of Rhizoma Coptidis, 200 parts of Fructus Crataegis, 150 parts of Cortex Fraxinis by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition of compound bee-glue of treating piglet pujos blancos and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of Rhizoma Atractylodis, 150 parts of Radix Sophorae Flavescentiss, 150 parts of propolis by weight, mix 5-10 minute to even;
(3) take by weighing 200 parts of the Radix Pulsatillaes, 200 parts of Rhizoma Coptidis, 300 parts of Fructus Crataegis, 250 parts of Cortex Fraxinis by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition of compound bee-glue of treating piglet pujos blancos and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of Rhizoma Atractylodis, 350 parts of Radix Sophorae Flavescentiss, 350 parts of propolis by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of the Radix Pulsatillaes, 250 parts of Rhizoma Coptidis, 400 parts of Fructus Crataegis, 350 parts of Cortex Fraxinis by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects for use 10-25 age in days, body weight at 10kg-30kg, and laboratory is diagnosed as the ill piglet of piglet pujos blancos.Ill piglet is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, 20 every group, 3 groups of feeding environments are identical; The blank group is left intact, and the medicine matched group uses treatment with " piglet pujos blancos looses " by specification; Chinese medicine composition group of the present invention can be with the ill piglet of product feeding of the present invention, and a day dose is: pig is by per kilogram of body weight 0.2-0.5g, and spice is fed, every day 3 times, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment piglet pujos blancos:
Numbering Group Mortality rate % Cure rate % Symptom rate % is arranged during end
I The blank group 16.5 43.0 40.5
II Piglet pujos blancos looses and organizes 7.2 77.7 15.1
III Chinese medicine composition group of the present invention 4.1 87.0 8.9
This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with piglet pujos blancos and compared difference extremely significantly (P<0.01).
Above-mentioned detailed description of pure Chinese medicine composition of compound bee-glue of this treatment piglet pujos blancos and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. pure Chinese medicine composition of compound bee-glue of treating piglet pujos blancos, it is characterized in that by following component by weight mixed preparing form: Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part, Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part.
2. the pure Chinese medicine composition of the compound bee-glue of treatment piglet pujos blancos according to claim 1, it is characterized in that by following component by weight mixed preparing form: 20 parts of Rhizoma Atractylodis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of propolis, 20 parts of the Radix Pulsatillaes, 20 parts of Rhizoma Coptidis, 30 parts of Fructus Crataegis, 25 parts of Cortex Fraxinis.
3. the method for preparing of the pure Chinese medicine composition of compound bee-glue of a treatment piglet pujos blancos according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
CN201210137256.8A 2012-05-07 2012-05-07 Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof Expired - Fee Related CN102670770B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494905A (en) * 2013-09-28 2014-01-08 中国农业科学院兰州畜牧与兽药研究所 Medicine composition for preventing and treating piglet diarrhea as well as preparation method and application thereof
CN103520516A (en) * 2013-09-27 2014-01-22 青岛绿曼生物工程有限公司 Pure traditional Chinese medicine composition for treatment of piglet yellow-white dysentery and preparation method thereof
CN105582413A (en) * 2016-01-20 2016-05-18 山东迅达康生物科技有限公司 Pharmaceutical composition for preventing and treating piglet diarrhea and preparation method of pharmaceutical composition
CN106266539A (en) * 2016-08-26 2017-01-04 任英明 A kind of herbal medicine treating piglet pujos blancos

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101579408A (en) * 2008-05-13 2009-11-18 天津生机集团股份有限公司 Chinese medicine powder for preventing and treating white diarrhea for baby pigs and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101579408A (en) * 2008-05-13 2009-11-18 天津生机集团股份有限公司 Chinese medicine powder for preventing and treating white diarrhea for baby pigs and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520516A (en) * 2013-09-27 2014-01-22 青岛绿曼生物工程有限公司 Pure traditional Chinese medicine composition for treatment of piglet yellow-white dysentery and preparation method thereof
CN103494905A (en) * 2013-09-28 2014-01-08 中国农业科学院兰州畜牧与兽药研究所 Medicine composition for preventing and treating piglet diarrhea as well as preparation method and application thereof
CN103494905B (en) * 2013-09-28 2015-11-18 中国农业科学院兰州畜牧与兽药研究所 A kind of pharmaceutical composition preventing and treating piglet diarrhea and its preparation method and application
CN105582413A (en) * 2016-01-20 2016-05-18 山东迅达康生物科技有限公司 Pharmaceutical composition for preventing and treating piglet diarrhea and preparation method of pharmaceutical composition
CN106266539A (en) * 2016-08-26 2017-01-04 任英明 A kind of herbal medicine treating piglet pujos blancos

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