CN102670770B - Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof - Google Patents
Compound propolis pure Chinese medicinal composition for treating white scour of piglets and preparation method thereof Download PDFInfo
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- CN102670770B CN102670770B CN201210137256.8A CN201210137256A CN102670770B CN 102670770 B CN102670770 B CN 102670770B CN 201210137256 A CN201210137256 A CN 201210137256A CN 102670770 B CN102670770 B CN 102670770B
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Abstract
The invention discloses a compound propolis pure Chinese medicinal composition for treating white scour of piglets. The compound propolis pure Chinese medicinal composition is prepared by mixing the following components in parts by weight: 10-35 parts of Chinese atractylodes, 10-35 parts of lightyellow sophora root, 10-35 parts of propolis, 15-25 parts of Chinese pulsatilla root, 15-25 parts of coptis root, 20-40 parts of fructus crataegi and 15-35 parts of ash bark. A preparation method of the compound propolis pure Chinese medicinal composition comprises the following steps of: (1) finely grinding each component in a composition, and sieving with a 700-mesh sieve; (2) weighing 10-35 parts by weight of Chinese atractylodes, 10-35 parts by weight of lightyellow sophora root and 10-35 parts by weight of propolis, and mixing for 5-10 minutes to a uniform state; (3) weighing 15-25 parts by weight of Chinese pulsatilla root, 15-25 parts by weight of coptis root, 20-40 parts by weight of fructus crataegi and 15-35 parts by weight of ash bark, and mixing for 5-10 minutes to a uniform state; and (4) combining compositions prepared in the steps (2) and (3), and continually mixing for 10-15 minutes to a uniform state. The compound propolis pure Chinese medicinal composition has the beneficial effects of reasonable composition, easiness for preparing, freeness from toxic and side effects, no medicament residues, and very remarkable curative effect; and as proved by clinic, the compound propolis pure Chinese medicinal composition has a special treatment effect on white scour of piglets.
Description
Technical field
The present invention relates to a kind of compound propolis pure Chinese medicinal composition and preparation method thereof, belong to the animal field of medicaments, particularly a kind of compound propolis pure Chinese medicinal composition that is specifically designed to the treatment piglet pujos blancos and preparation method thereof.
Background technology
Piglet pujos blancos is a kind of common alimentary infection disease caused by escherichia coli, and take clinically diarrhoea, ash discharge white, stench, paste shape loose stool is feature, and sickness rate is between 30%-80%, and mortality rate is more than 10%, very large to the harm of piglet.
The pathogen of primary disease is escherichia coli, and this disease spreads all over more than 100 countries of five continents, is widely distributed.At present, treat this disease the most frequently used be various antibacterials, as oxytetracycline, chloromycetin, penicillin, streptomycin, quinolinones etc.; Due to the prolonged and repeated use of antibacterials, cause this pathogenic microorganism to produce drug resistance to medicine, reduced curative effect, and drug residue is in animal body, its meat does not reach nuisanceless requirement, has affected the outlet of livestock products and people's health.
Therefore researching and developing a kind of specific medicament for the treatment of piglet pujos blancos is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, have no side effect, drug residue free, effectively treat compound propolis pure Chinese medicinal composition of piglet pujos blancos and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of compound propolis pure Chinese medicinal composition for the treatment of piglet pujos blancos, by following component by weight mixed preparing form: Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part, Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part.
On the basis of such scheme, described various component optimum ratio amounts are: 20 parts of Rhizoma Atractylodis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of propolis, 20 parts of the Radix Pulsatillaes, 20 parts of Rhizoma Coptidis, 30 parts of Fructus Crataegis, 25 parts of Cortex Fraxinis.
A kind of preparation method for the treatment of the compound propolis pure Chinese medicinal composition of piglet pujos blancos, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part, mix 5-10 minute to even;
(3) take by weight Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Propolis: bitter, acrid, cold, return spleen, lung, stomach warp, there is anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa etc.
Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach, Liver Channel, there is the function of drying damp and strengthening spleen, expelling wind and cold, improving eyesight; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold etc.
Fructus Crataegi: sour, sweet, tepor, return stomach, spleen, Liver Channel, there is the function of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis; Cure mainly dyspeptic abdominal flatulence, dyspepsia, prolonged lochia etc.
Radix Sophorae Flavescentis: Radix Sophorae Flavescentis: bitter, cold, return liver, the heart, stomach, large intestine, urinary bladder channel, have that heat clearing and damp drying, parasite killing go to amass, the function of diuretic; Cure mainly damp-heat dysentery etc.
Rhizoma Coptidis: bitter, cold, return spleen, stomach, large intestine, gallbladder, heart channel, there is the function of heat clearing and damp drying, eliminating fire and detoxication; Cure mainly damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder etc.
The Radix Pulsatillae: bitter, cold, return stomach, large intestine channel, there is the function of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Cure mainly toxic-heat and blood stasis, damp and hot intestinal Huang etc.
Cortex Fraxini: bitter, puckery, cold, return liver, gallbladder, large intestine channel, there is the function of heat clearing and damp drying, astringent therapy dysentery relieving, improving eyesight; Cure mainly damp-heat diarrhea, conjunctival congestion and swelling pain, nebula etc.
Above all flavor Chinese medicine, according to the tcm theory compatible combination, for pathogenic microorganism and the clinical symptoms of piglet pujos blancos, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and the generation that has no drug resistance, cost is low, draws materials wide, the curative effect highly significant.Adopt pharmacology and the Chinese veterinarian of motherland determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs method, optimize this seven kinds of medicines, and make them according to optimum ratio, form pure Chinese powder medicine, clinical practice proves that the treatment piglet pujos blancos is had to specially good effect.And make the livestock products meat reach nuisanceless requirement, meet the export standard of livestock products, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of compound propolis pure Chinese medicinal composition for the treatment of piglet pujos blancos and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 100 parts of Rhizoma Atractylodis, 100 parts of Radix Sophorae Flavescentiss, 100 parts of propolis, mix 5-10 minute to even;
(3) take by weight 150 parts of the Radix Pulsatillaes, 150 parts of Rhizoma Coptidis, 200 parts of Fructus Crataegis, 150 parts of Cortex Fraxinis, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound propolis pure Chinese medicinal composition for the treatment of piglet pujos blancos and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 150 parts of Rhizoma Atractylodis, 150 parts of Radix Sophorae Flavescentiss, 150 parts of propolis, mix 5-10 minute to even;
(3) take by weight 200 parts of the Radix Pulsatillaes, 200 parts of Rhizoma Coptidis, 300 parts of Fructus Crataegis, 250 parts of Cortex Fraxinis, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound propolis pure Chinese medicinal composition for the treatment of piglet pujos blancos and preparation method thereof: it is characterized in that carrying out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 350 parts of Rhizoma Atractylodis, 350 parts of Radix Sophorae Flavescentiss, 350 parts of propolis, mix 5-10 minute to even;
(3) take by weight 250 parts of the Radix Pulsatillaes, 250 parts of Rhizoma Coptidis, 400 parts of Fructus Crataegis, 350 parts of Cortex Fraxinis, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects 10-25 age in days, body weight at 10kg-30kg, the ill piglet that Laboratory Diagnosed is piglet pujos blancos.Ill piglet isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, 20 every group, 3 groups of feeding environments are identical; The blank group is left intact, and the medicine matched group is used treatment with " piglet pujos blancos is loose " by specification; Chinese medicine composition group of the present invention can be by the ill piglet of product feeding of the present invention, and a day dose is: pig is by per kilogram of body weight 0.2-0.5g, and spice is fed, and every day 3 times, is used in conjunction 3-5 day; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment piglet pujos blancos:
Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
I | The blank group | 16.5 | 43.0 | 40.5 |
II | The piglet pujos blancos group of faling apart | 7.2 | 77.7 | 15.1 |
III | Chinese medicine composition group of the present invention | 4.1 | 87.0 | 8.9 |
This clinical effectiveness statistical analysis, present composition treatment group is compared difference extremely significantly (P<0.01) with the loose group of piglet pujos blancos.
Above-mentioned detailed description of compound propolis pure Chinese medicinal composition of this treatment piglet pujos blancos and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (3)
1. a compound bee-glue Chinese medicine composition for the treatment of piglet pujos blancos, it is characterized in that by following component by weight mixed preparing form: Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part, Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part.
2. the compound bee-glue Chinese medicine composition for the treatment of piglet pujos blancos according to claim 1, it is characterized in that by following component by weight mixed preparing form: 20 parts of Rhizoma Atractylodis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of propolis, 20 parts of the Radix Pulsatillaes, 20 parts of Rhizoma Coptidis, 30 parts of Fructus Crataegis, 25 parts of Cortex Fraxinis.
3. the preparation method of the compound bee-glue Chinese medicine composition of a treatment piglet pujos blancos according to claim 1 is characterized in that carrying out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Rhizoma Atractylodis 10-35 part, Radix Sophorae Flavescentis 10-35 part, propolis 10-35 part, mix 5-10 minute to even;
(3) take by weight Radix Pulsatillae 15-25 part, Rhizoma Coptidis 15-25 part, Fructus Crataegi 20-40 part, Cortex Fraxini 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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CN103520516A (en) * | 2013-09-27 | 2014-01-22 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of piglet yellow-white dysentery and preparation method thereof |
CN103494905B (en) * | 2013-09-28 | 2015-11-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pharmaceutical composition preventing and treating piglet diarrhea and its preparation method and application |
CN105582413A (en) * | 2016-01-20 | 2016-05-18 | 山东迅达康生物科技有限公司 | Pharmaceutical composition for preventing and treating piglet diarrhea and preparation method of pharmaceutical composition |
CN106266539A (en) * | 2016-08-26 | 2017-01-04 | 任英明 | A kind of herbal medicine treating piglet pujos blancos |
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CN101579408A (en) * | 2008-05-13 | 2009-11-18 | 天津生机集团股份有限公司 | Chinese medicine powder for preventing and treating white diarrhea for baby pigs and preparation method thereof |
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