CN102397401B - Compound propolis pure traditional Chinese medicine composition for treating birds necrotic enteritis and preparation method thereof - Google Patents
Compound propolis pure traditional Chinese medicine composition for treating birds necrotic enteritis and preparation method thereof Download PDFInfo
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- CN102397401B CN102397401B CN2011103606787A CN201110360678A CN102397401B CN 102397401 B CN102397401 B CN 102397401B CN 2011103606787 A CN2011103606787 A CN 2011103606787A CN 201110360678 A CN201110360678 A CN 201110360678A CN 102397401 B CN102397401 B CN 102397401B
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Abstract
A compound propolis pure traditional Chinese medicine composition for treating birds necrotic enteritis and a preparation method thereof relate to the field of animal medicine. The preparation method of the composition comprises steps of : (1) carrying out superfine pulverizing on each component in a formula and sieving through a 700 mesh screen; (2) weighing, by weight, 15-35 parts of propolis, 10-25 parts of fructus gardeniae, 15-35 parts of liquorice and 15-35 parts of guava leaf, and mixing uniformly for 5-10 min; (3) weighing, by weight, 15-15 parts of scutellaria baicalensis, 15-35 parts of astragalus mongholicus, 15-45 parts of mung bean and 10-35 parts of fruit of Chinese wolfberry, and mixing uniformly for 5-10 min; (4) mixing the compositions from step (2) and step (3) and continuing to mix uniformly for 10-15 min. The invention has beneficial effects of reasonable formula, simple preparation, pure traditional Chinese medicine composition without toxic or side effect, pollution, medicine residual or tolerance, superfine pulverizing, high bioavailability, substantial curative effect. The traditional Chinese medicine composition is proved to have special efficiency on treating birds necrotic enteritis on clinic.
Description
Technical field
The present invention relates to the animal field of medicaments, particularly a kind of pure Chinese medicine composition of compound bee-glue for the treatment of the fowl necrotic enteritis and preparation method thereof.
Background technology
The fowl necrotic enteritis is the acute untouchable infectious disease that is caused by a kind of clostridieum welchii toxin, and the chicken in age in main harm 2-5 week is feature with the mucous membrane of small intestine necrosis, and mortality rate is Gao Keda 50% very, very harmful to poultry.
The pathogen of primary disease is clostridieum welchii, and this disease spreads all over more than 100 countries of five continents, and it is very extensive to distribute.At present, treat this disease the most frequently used be various antibacterials, as tylosin, penicillin etc.; Because the prolonged and repeated use of antibacterials causes this pathogenic microorganism that medicine has been produced drug resistance, reduced curative effect, and drug residue in animal body, its meat does not reach nuisanceless requirement, has influenced the healthy of the outlet of poultry product and people.
Therefore researching and developing a kind of specific medicament for the treatment of the fowl necrotic enteritis is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, effect obviously, have no drug resistance and the pure Chinese medicine composition of compound bee-glue of effective treatment fowl necrotic enteritis of toxic and side effects and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition of compound bee-glue for the treatment of the fowl necrotic enteritis, by following component by weight mixed preparing form: propolis 15-35 part, Fructus Gardeniae 10-25 part, Radix Glycyrrhizae 15-35 part, Folium Psidii Guajavae 15-35 part, Radix Scutellariae 15-25 part, Radix Astragali 15-35 part, Semen phaseoli radiati 15-45 part, Fructus Lycii 10-35 part.
Described various component optimum ratio amount is: 25 parts of propolis, 15 parts of Fructus Gardeniaes, 25 parts in Radix Glycyrrhizae, 25 parts of Folium Psidii Guajavae, 20 parts of Radix Scutellariaes, 25 parts of the Radixs Astragali, 35 parts in Semen phaseoli radiati, 25 parts of Fructus Lycii.
A kind of preparation method for the treatment of the pure Chinese medicine composition of compound bee-glue of fowl necrotic enteritis, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Fructus Gardeniae 10-25 part, Radix Glycyrrhizae 15-35 part, Folium Psidii Guajavae 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Scutellariae 15-25 part, Radix Astragali 15-35 part, Semen phaseoli radiati 15-45 part, Fructus Lycii 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Propolis: bitter, hot, cold, return spleen, stomach warp, have the function of anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, raising immunity, antiallergic oxidation, hemostasis protozoacide, protection gastrointestinal mucosa.
Fructus Gardeniae: bitter, cold, GUIXIN, lung, tri-jiao channel have the function of eliminating fire and detoxication, clearing away heat and promoting diuresis, removing heat from blood; Cure mainly three warmers intenseness of heat, jaundice due to damp-heat, pyretic stranguria, heat in blood epistaxis etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Folium Psidii Guajavae: sweet, puckery, flat, return liver, large intestine channel, have relieving diarrhea with astringents, astringing to arrest bleeding, drying damp and strengthening spleen function; Cure mainly that dysentery is suffered from abdominal pain, had loose bowels, dysentery is more than.
Radix Scutellariae: bitter, cold, return gallbladder, lung, spleen, large intestine, small intestine meridian, have the function of heat clearing and damp drying, eliminating fire and detoxication, hemostasis; Cure mainly that cough due to lung-heat, gastrointestinal are damp and hot, dysentery, jaundice, have blood in stool, epistaxis, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus etc.
The Radix Astragali: sweet, tepor, return spleen, lung meridian, have the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
Semen phaseoli radiati: sweet, cool, GUIXIN, stomach warp have heat-clearing and toxic substances removing, a function of the stomach invigorating of relieving summer heat; Cure mainly that diarrhea due to damp-heat, detoxifcation protect the liver, antiallergic etc.
Fructus Lycii: sweet, flat, return liver, kidney channel, have the function of liver and kidney tonifying, replenishing vital essence to improve eyesight; It is unable etc. to cure mainly the hepatic and renal YIN deficiency, waist.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, at pathogenic microorganism and the clinical symptoms of fowl necrotic enteritis, the performance treating both the principal and secondary aspects of a disease effect.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, micronizing, bioavailability height, curative effect highly significant.The present invention optimizes this eight flavors Chinese medicine, and makes them form pure Chinese powder medicine according to optimum ratio according to Chinese veterinarian's traditional theory, and clinical practice proves that treatment fowl necrotic enteritis is had specially good effect.And make the poultry product meat reach nuisanceless requirement, satisfy the export standard of poultry product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of pure Chinese medicine composition of compound bee-glue for the treatment of the fowl necrotic enteritis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 100 parts of Fructus Gardeniaes, 150 parts in Radix Glycyrrhizae, 150 parts of Folium Psidii Guajavae by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Radix Scutellariaes, 150 parts of the Radixs Astragali, 150 parts in Semen phaseoli radiati, 100 parts of Fructus Lycii by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition of compound bee-glue for the treatment of the fowl necrotic enteritis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 150 parts of Fructus Gardeniaes, 250 parts in Radix Glycyrrhizae, 250 parts of Folium Psidii Guajavae by weight, mix 5-10 minute to even;
(3) take by weighing 200 parts of Radix Scutellariaes, 250 parts of the Radixs Astragali, 300 parts in Semen phaseoli radiati, 250 parts of Fructus Lycii by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition of compound bee-glue for the treatment of the fowl necrotic enteritis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis propolis, 250 parts of Fructus Gardeniaes, 350 parts in Radix Glycyrrhizae, 350 parts of Folium Psidii Guajavae by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Radix Scutellariaes, 350 parts of the Radixs Astragali, 450 parts in Semen phaseoli radiati, 350 parts of Fructus Lycii by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
With the ill poultry of product feeding of the present invention etc., a day dose is: by the every 100g of the present invention, spice 200kg feeds, and drinking-water 400kg, is used in conjunction 3-5 day at every day 2-3 time; Oral back reaches the purpose for the treatment of disease by gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment fowl necrotic enteritis:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 15.9 | 66.9 | 17.2 |
| II | The tylosin group | 9.8 | 79.7 | 10.5 |
| III | Penicillium sp mycin group | 7.4 | 84.2 | 8.4 |
| IV | Chinese medicine composition group of the present invention | 4.3 | 90.9 | 4.8 |
This clinical effectiveness is analyzed by statistics, and present composition treatment group is compared difference all extremely remarkable or remarkable (P＜0.01 or P＜0.05) with tylosin group, penicillin group.
Above-mentioned detailed description of pure Chinese medicine composition of compound bee-glue of this treatment fowl necrotic enteritis and preparation method thereof being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. pure Chinese medicine composition of compound bee-glue for the treatment of the fowl necrotic enteritis, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Fructus Gardeniae 10-25 part, Radix Glycyrrhizae 15-35 part, Folium Psidii Guajavae 15-35 part, Radix Scutellariae 15-25 part, Radix Astragali 15-35 part, Semen phaseoli radiati 15-45 part, Fructus Lycii 10-35 part.
2. the pure Chinese medicine composition of compound bee-glue for the treatment of fowl necrotic enteritis according to claim 1 is characterized in that described various component optimum ratio amount is: 25 parts of propolis, 15 parts of Fructus Gardeniaes, 25 parts in Radix Glycyrrhizae, 25 parts of Folium Psidii Guajavae, 20 parts of Radix Scutellariaes, 25 parts of the Radixs Astragali, 35 parts in Semen phaseoli radiati, 25 parts of Fructus Lycii.
3. the preparation method of the pure Chinese medicine composition of compound bee-glue of a treatment according to claim 1 and 2 fowl necrotic enteritis is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Fructus Gardeniae 10-25 part, Radix Glycyrrhizae 15-35 part, Folium Psidii Guajavae 15-35 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Scutellariae 15-25 part, Radix Astragali 15-35 part, Semen phaseoli radiati 15-45 part, Fructus Lycii 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN2011103606787A CN102397401B (en) | 2011-11-15 | 2011-11-15 | Compound propolis pure traditional Chinese medicine composition for treating birds necrotic enteritis and preparation method thereof |
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| CN2011103606787A CN102397401B (en) | 2011-11-15 | 2011-11-15 | Compound propolis pure traditional Chinese medicine composition for treating birds necrotic enteritis and preparation method thereof |
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| CN102397401B true CN102397401B (en) | 2013-10-09 |
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| CN103690876B (en) * | 2013-12-31 | 2015-11-11 | 芜湖乐锐思信息咨询有限公司 | For the Chinese medicine preparation of canine parvoviral enteritis |
Citations (2)
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| CN1075251A (en) * | 1992-02-12 | 1993-08-18 | 张秀柱 | 16 kinds of difference in functionality health-care toothpastes and processing technology |
| CN1506108A (en) * | 2002-12-09 | 2004-06-23 | 戚海燕 | Composite milk powder capable of being eaten and made into beautifying face mask |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1075251A (en) * | 1992-02-12 | 1993-08-18 | 张秀柱 | 16 kinds of difference in functionality health-care toothpastes and processing technology |
| CN1506108A (en) * | 2002-12-09 | 2004-06-23 | 戚海燕 | Composite milk powder capable of being eaten and made into beautifying face mask |
Non-Patent Citations (6)
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| 中草药防治鸡病的饲养模式探讨;雷红等;《中兽医学杂志》;20020630(第02期);第36页第2栏第1-5段、第37页第1栏第1-3段 * |
| 中药抗病毒临床实验研究概况;傅谧亚;《天津中医学院学报》;20020630;第21卷(第02期);第49页第1栏第2段 * |
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| 鸡小肠球虫病与坏死性肠炎混合感染的诊断和治疗;王芳等;《中国禽业导刊》;20100831;第27卷(第17期);51 * |
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