CN102357148B - Pure Chinese herbal composition for treating Riemerella anatipestifer disease and preparation method thereof - Google Patents
Pure Chinese herbal composition for treating Riemerella anatipestifer disease and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a pure Chinese herbal composition for treating Riemerella anatipestifer disease and a preparation method thereof, relating to the fields of medicines for poultry and preparation methods thereof. The preparation method comprises the following steps: (1) superfinely crushing all the components in a formula respectively and sieving the crushed components with a 500-mesh sieve; (2) weighing, by weight, 15 to 25 parts of propolis, 10 to 25 parts of coptis, 15 to 25 parts of phellodendron and 10 to 20 parts of pasque flower, and carrying out mixing on the components for 5 to10 minutes so as to uniformly mix the components; (3) weighing, by weight, 10 to 25 parts of dandelion, 10 to 25 parts of licorice, 15 to 30 parts of cordate houttuynia and 10 to 20 parts of birthwort root, and carrying out mixing on the components for 5 to 10 minutes so as to uniformly mix the components; (4) merging the compositions obtained in step (2) and step (3), and continuing mixing for 10 to 15 minutes to uniformly mix the two compositions so as to obtain the pure Chinese herbal composition. The beneficial effects of the invention are as follows: a reasonable formula, simple preparation, a pure Chinese herbal composition having no toxic and side effects, no pollution, no drug residue, superfine crushing, high bioavailability, a remarkable curative effect, and special efficacy on treatment of the Riemerella anatipestifer disease according to results of clinical practice.
Description
Technical field
The present invention relates to fowl medicine and fowl medicine preparation field, particularly a kind of pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection and preparation method thereof.
Background technology
Riemerella anatipestifer infection is a kind of common acute septic infectious disease that is caused by riemerella anatipestifer, mainly infect the 2-3 duckling in age in week, infected duck is feature with fibrinous pericarditis, perihepatitis, airsacculitis, cheesy salpingitis and meningitis, mortality rate reaches as high as 75%-80%, is that one of duck principal disease is already supported in harm.
The pathogen of primary disease is riemerella anatipestifer, and this disease spreads all over more or less a hundred country of five continents, and it is very extensive to distribute.At present, treat this disease the most frequently used be Chinese medicine and antimicrobial drug, Chinese medicine is because its prescription is unreasonable or simple pulverizing the just, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And the prolonged and repeated use of various antimicrobial drug example hydrochloric acid ciprofloxacins, streptomycin sulfate, florfenicol etc., cause this pathogenic microorganism that antibacterials have been produced drug resistance, reduced curative effect, and drug residue in animal body, its meat does not reach nuisanceless requirement, has influenced the outlet of livestock products and people's health.
Therefore researching and developing a kind of specific medicament for the treatment of the drug residue free of Riemerella anatipestifer infection, the generation that has no drug resistance is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability height, effect obviously, have no drug resistance and the pure Chinese medicine composition of effective treatment Riemerella anatipestifer infection of drug residue and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection, be by following component by weight mixed preparing form: propolis 15-25 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 15-25 part, Radix Pulsatillae 10-20 part, Herba Taraxaci 10-25 part, Radix Glycyrrhizae 10-25 part, Herba Houttuyniae 15-30 part, Radix Aristolochiae 10-20 part.
Described various component optimum ratio amount is: 20 parts of propolis, 20 parts of Rhizoma Coptidis, 20 parts of Cortex Phellodendris, 15 parts of the Radix Pulsatillaes, 20 parts of Herba Taraxacis, 20 parts in Radix Glycyrrhizae, 25 parts of Herba Houttuyniae, 15 parts of Radix Aristolochiaes.
A kind of preparation method for the treatment of the pure Chinese medicine composition of Riemerella anatipestifer infection is to carry out as follows:
(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-25 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 15-25 part, Radix Pulsatillae 10-20 part by weight, mix 5-10 minute to even;
(3) take by weighing Herba Taraxaci 10-25 part, Radix Glycyrrhizae 10-25 part, Herba Houttuyniae 15-30 part, Radix Aristolochiae 10-20 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Propolis: bitter, hot, cold, return spleen, stomach warp, have the function of anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, raising immunity, antiallergic oxidation, hemostasis, protection gastrointestinal mucosa.
Rhizoma Coptidis: cold, bitter, return liver, stomach, spleen, the heart, gallbladder, large intestine channel, have the function of sharp clearly scorching, eliminating fire and detoxication; Cure mainly damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder, fire-toxin carbuncle sore.
Cortex Phellodendri: bitter, cold, return kidney, urinary bladder channel, have the function of heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever; Cure mainly damp-heat dysentery, jaundice, pyretic stranguria, sore swollen toxin, eczema, hyperactivity of fire caused by deficiency of YIN etc.
The Radix Pulsatillae: bitter, cold, return stomach, large intestine channel, have the function of heat-clearing and toxic substances removing, damp and hot intestinal Huang; Cure mainly toxic-heat and blood stasis, damp and hot intestinal Huang.
Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp, have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; Cure mainly sore, lung abscess, pharyngalgia, jaundice due to damp-heat, pyretic stranguria.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning.
Herba Houttuyniae: hot, be slightly cold, return lung meridian, have the function of heat-clearing and toxic substances removing, detumescence and apocenosis, inducing diuresis for treating stranguria syndrome; Cure mainly lung abscess, intestinal Huang, dysentery, stranguria with turbid discharge, acute mastitis.
Radix Aristolochiae: hot, bitter, cold, attach to the lung and stomach meridians, have the function of circulation of qi promoting removing food stagnancy, pain relieving, subduing swelling and detoxicating; Cure mainly stagnation of QI abdominal distention, breast abdomen pain, the yellow furunculosis of skin ulcer.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, at pathogenic microorganism, clinical symptoms and the pathological change of Riemerella anatipestifer infection, the performance treating both the principal and secondary aspects of a disease effect.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, micronizing, bioavailability height, curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory, optimize this eight flavors Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, the treatment Riemerella anatipestifer infection there is specially good effect, and make its product meat reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 100 parts of Rhizoma Coptidis, 150 parts of Cortex Phellodendris, 100 parts of the Radix Pulsatillaes by weight, mix 5-10 minute to even;
(3) take by weighing 100 parts of Herba Taraxacis, 100 parts in Radix Glycyrrhizae, 150 parts of Herba Houttuyniae, 100 parts of Radix Aristolochiaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;
(2) take by weighing 200 parts of propolis, 150 parts of Rhizoma Coptidis, 200 parts of Cortex Phellodendris, 150 parts of the Radix Pulsatillaes by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Herba Taraxacis, 150 parts in Radix Glycyrrhizae, 200 parts of Herba Houttuyniae, 150 parts of Radix Aristolochiaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 250 parts of Rhizoma Coptidis, 250 parts of Cortex Phellodendris, 200 parts of the Radix Pulsatillaes by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Herba Taraxacis, 250 parts in Radix Glycyrrhizae, 300 parts of Herba Houttuyniae, 200 parts of Radix Aristolochiaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
With the ill duck of product feeding of the present invention etc., a day dose is: by the every 100g of the present invention, spice 200kg feeds, and drinking-water 450kg, is used in conjunction 3-5 day at every day 2-3 time; Oral back reaches the purpose for the treatment of disease by gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment Riemerella anatipestifer infection:
| Compile | Group | Dead | Cure | Symptom is arranged during end |
| I | The blank group | 12.1 | 65.2 | 22.7 |
| II | The pest of duck health is loose and is organized | 8.2 | 77.9 | 13.9 |
| III | Duck serous coat recovery oral liquid | 7.7 | 81.0 | 11.3 |
| IV | Chinese medicine composition of the present invention | 6.0 | 86.1 | 7.9 |
This clinical effectiveness is analyzed by statistics, and present composition treatment group is being compared difference all extremely significantly (P＜0.01) and significantly (P＜0.05) with the diffusing group of pest of duck health, duck serous coat recovery oral liquid group aspect the cure rate.
Above-mentioned detailed description of pure Chinese medicine composition of this treatment Riemerella anatipestifer infection and preparation method thereof being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection, it is characterized in that by following component by weight mixed preparing form: propolis 15-25 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 15-25 part, Radix Pulsatillae 10-20 part, Herba Taraxaci 10-25 part, Radix Glycyrrhizae 10-25 part, Herba Houttuyniae 15-30 part, Radix Aristolochiae 10-20 part.
2. a kind of pure Chinese medicine composition for the treatment of Riemerella anatipestifer infection according to claim 1 is characterized in that described various component optimum ratio amount is: 20 parts of propolis, 20 parts of Rhizoma Coptidis, 20 parts of Cortex Phellodendris, 15 parts of the Radix Pulsatillaes, 20 parts of Herba Taraxacis, 20 parts in Radix Glycyrrhizae, 25 parts of Herba Houttuyniae, 15 parts of Radix Aristolochiaes.
3. the preparation method of the pure Chinese medicine composition of a treatment Riemerella anatipestifer infection according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-25 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 15-25 part, Radix Pulsatillae 10-20 part by weight, mix 5-10 minute to even;
(3) take by weighing Herba Taraxaci 10-25 part, Radix Glycyrrhizae 10-25 part, Herba Houttuyniae 15-30 part, Radix Aristolochiae 10-20 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN102357148B true CN102357148B (en) | 2013-09-18 |
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Families Citing this family (3)
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| CN103520534A (en) * | 2013-09-27 | 2014-01-22 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of duck riemerella anatipestifer disease and preparation method thereof |
| CN108434262A (en) * | 2018-06-30 | 2018-08-24 | 信阳农林学院 | A kind of Chinese medicine composition of prevention and treatment Riemerella anatipestifer disease |
| CN109432282A (en) * | 2018-12-28 | 2019-03-08 | 河北肽都生物科技有限公司 | A kind of Chinese medicine peptide and preparation method thereof for preventing and treating Riemerella anatipestifer disease |
Citations (2)
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| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101396514A (en) * | 2007-09-29 | 2009-04-01 | 张勇 | Traditional Chinese medicine formula for treating Asia (African) fowl plague |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101396514A (en) * | 2007-09-29 | 2009-04-01 | 张勇 | Traditional Chinese medicine formula for treating Asia (African) fowl plague |
Non-Patent Citations (6)
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| 30味中药及其复方对鸭疫里默氏杆菌的体外抑菌作用;何永明等;《安徽农业科学》;20080229(第06期);2351-2352 * |
| 何永明等.30味中药及其复方对鸭疫里默氏杆菌的体外抑菌作用.《安徽农业科学》.2008,(第06期), |
| 卢家平等.防治鸭疫里默氏杆菌病存在的问题与对策.《养禽与禽病防治》.2003,(第07期), |
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| 鸭疫里默氏杆菌病的防治;胡萍;《北方牧业》;20090130(第02期);第21页本文第2栏第3段-第3栏第1段 * |
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