CN102727769B - Pure Chinese herbal composition for treating white scour of piglets and its preparation method - Google Patents
Pure Chinese herbal composition for treating white scour of piglets and its preparation method Download PDFInfo
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- CN102727769B CN102727769B CN2012102000990A CN201210200099A CN102727769B CN 102727769 B CN102727769 B CN 102727769B CN 2012102000990 A CN2012102000990 A CN 2012102000990A CN 201210200099 A CN201210200099 A CN 201210200099A CN 102727769 B CN102727769 B CN 102727769B
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Abstract
The invention relates to a pure Chinese herbal composition for treating white scour of piglets. The composition is prepared by mixing the following components by weight: 15 to 35 parts of atractylodes rhizome, 10 to 20 parts of debark peony root, 10 to 35 parts of Chinese yam, 15 to 45 parts of oriental waterplantain rhizome, 15 to 45 parts of Chinese sorghum, 20 to 40 parts of Chinese gentian and 15 to 35 parts of liquorice root. The invention has the following beneficial effects: a reasonable recipe is formulated; preparation of the composition is simple; the pure Chinese herbal composition has no toxic and side effects, no drug residue and a substantial therapeutic effect; and according to clinical results, it is proved that the medicine has special efficacy on treating white scour of piglets.
Description
Technical field
The present invention relates to pure Chinese medicine composition for the treatment of piglet pujos blancos and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to the treatment piglet pujos blancos and preparation method thereof.
Background technology
Piglet pujos blancos is a kind of common alimentary infection disease caused by escherichia coli, and take clinically diarrhoea, ash discharge white, stench, paste shape loose stool is feature, and sickness rate is between 30%-80%, and mortality rate is more than 10%, very large to the harm of piglet.
The pathogen of primary disease is escherichia coli, and this disease spreads all over more than 100 countries of five continents, is widely distributed.At present, treat this disease the most frequently used be various antibacterials, as oxytetracycline, chloromycetin, penicillin, streptomycin, quinolinones etc.; Due to the prolonged and repeated use of antibacterials, cause this pathogenic microorganism to produce drug resistance to medicine, reduced curative effect, and drug residue is in animal body, its meat does not reach nuisanceless requirement, has affected the outlet of livestock products and people's health.
Therefore researching and developing a kind of specific medicament for the treatment of piglet pujos blancos is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, have no side effect, drug residue free, effectively treat pure Chinese medicine composition of piglet pujos blancos and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of piglet pujos blancos, by following component by weight mixed preparing form: Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part, Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part.
Described various component optimum ratio amount is: 25 parts of Rhizoma Atractylodis, 15 parts of the Radix Paeoniae Albas, 25 parts of Rhizoma Dioscoreaes, 30 parts of Rhizoma Alismatis, 30 parts of Sorghum vulgare Pers., 30 parts of Radix Gentianae, 25 parts, Radix Glycyrrhizae.
A kind of preparation method for the treatment of the pure Chinese medicine composition of piglet pujos blancos, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part, mix 5-10 minute to even;
(3) take by weight Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach, Liver Channel, there is the function of drying damp and strengthening spleen, expelling wind and cold, improving eyesight; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold etc.
The Radix Paeoniae Alba: bitter,, acid, be slightly cold, return liver, spleen channel, there is the suppressing the hyperactive liver pain relieving, the function of the yin fluid astringing that nourishes blood; Cure mainly deficiecny of liver-YIN, deficiency-heat, dysentery stomachache, spasm of the limbs etc.
Rhizoma Dioscoreae: sweet, flat, return spleen, stomach, lung meridian, have that spleen reinforcing nourishing the stomach, lung benefiting are promoted the production of body fluid, the function of the kidney invigorating arresting seminal emission; Cure mainly weakness of the spleen and stomach, inappetence, diarrhea due to hypofunction of the spleen, asthenia cough with asthma, spermatorrhea etc.
Rhizoma Alismatis: sweet, light, cold, return kidney, urinary bladder channel, there is the function of diuresis, clearing away damp-heat; Cure mainly dysuria, edema distension, diarrhea due to damp-heat etc.
Sorghum vulgare Pers.: bitter, sweet, flat, return stomach, spleen, lung, intestinal warp, there is the function of subduing swelling and detoxicating, promoting blood flow to regulate menstruation, stomach function regulating, removing food stagnancy, warming middle-JIAO, astringing intestine to stop diarrhea stomach, removing heat from blood; Cure mainly stagnation of dampness due to deficiency of the spleen, dyspepsia, damp-heat diarrhea, have blood in stool etc.
Radix Gentianae: bitter, cold, return liver, gallbladder meridian, there is eliminating pathogen in the liver gallbladder excess-fire, except the function of damp-heat in lower-JIAO; Cure mainly jaundice due to damp-heat, conjunctival congestion and swelling pain, eczema pruritus etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Above all flavor Chinese medicine, according to the tcm theory compatible combination, for pathogenic microorganism and clinical symptoms and the pathological change of piglet pujos blancos, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and the generation that has no drug resistance, cost is low, draws materials wide, the curative effect highly significant.Adopt pharmacology and the Chinese veterinarian of motherland determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs method, optimize this seven kinds of medicines, and make them according to optimum ratio, form pure Chinese powder medicine, clinical practice proves that the treatment piglet pujos blancos is had to specially good effect.And make the livestock products meat reach nuisanceless requirement, meet the export standard of livestock products, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of piglet pujos blancos and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 150 parts of Rhizoma Atractylodis, 100 parts of the Radix Paeoniae Albas, 100 parts of Rhizoma Dioscoreaes, mix 5-10 minute to even;
(3) take by weight 150 parts of Rhizoma Alismatis, 150 parts of Sorghum vulgare Pers., 200 parts of Radix Gentianae, 150 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of piglet pujos blancos and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 250 parts of Rhizoma Atractylodis, 150 parts of the Radix Paeoniae Albas, 150 parts of Rhizoma Dioscoreaes, mix 5-10 minute to even;
(3) take by weight 300 parts of Rhizoma Alismatis, 300 parts of Sorghum vulgare Pers., 300 parts of Radix Gentianae, 250 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of piglet pujos blancos and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 350 parts of Rhizoma Atractylodis, 200 parts of the Radix Paeoniae Albas, 350 parts of Rhizoma Dioscoreaes, mix 5-10 minute to even;
(3) take by weight 450 parts of Rhizoma Alismatis, 450 parts of Sorghum vulgare Pers., 400 parts of Radix Gentianae, 350 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects 10-25 age in days, body weight at 6.5kg-15kg, the ill piglet that Laboratory Diagnosed is piglet pujos blancos.Ill piglet isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 20 every group, 3 groups of feeding environments are identical, and experiment is carried out 5 days altogether; The blank group is left intact, and the medicine matched group is used treatment with " piglet pujos blancos is loose " by specification; Chinese medicine composition group of the present invention can be by the ill piglet of product feeding of the present invention etc., and a day dose is: pig is by per kilogram of body weight 0.2-0.45g, and spice is fed, and every day 3 times, is used in conjunction 3-5 day; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal is counted x100%.Result (testing the 5th day) when following table is the experiment end.
Table is the situation contrast of the present invention and other medicines treatment piglet pujos blancos:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 16.7 | 43.3 | 40.0 |
| II | The piglet pujos blancos group of faling apart | 6.7 | 76.6 | 16.7 |
| III | Chinese medicine composition of the present invention | 3.3 | 86.7 | 10.0 |
This clinical effectiveness statistical analysis, present composition treatment group is compared significant difference (P<0.05) with the loose group of piglet pujos blancos.
Safety testing:
Choose 10 of 70 age in days health pig, 5 times of spices according to the made compositions recommended dose of the embodiment of the present invention 1 are fed 10 days, during medication, health pig is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and body weight increases that to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of pure Chinese medicine composition of this treatment piglet pujos blancos and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (3)
1. a pure Chinese medicine composition for the treatment of piglet pujos blancos, it is characterized in that by following component by weight mixed preparing form: Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part, Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part.
2. the pure Chinese medicine composition for the treatment of piglet pujos blancos according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of Rhizoma Atractylodis, 15 parts of the Radix Paeoniae Albas, 25 parts of Rhizoma Dioscoreaes, 30 parts of Rhizoma Alismatis, 30 parts of Sorghum vulgare Pers., 30 parts of Radix Gentianae, 25 parts, Radix Glycyrrhizae.
3. the preparation method of the pure Chinese medicine composition of a treatment piglet pujos blancos according to claim 1 is characterized in that carrying out as follows:
(1) composition of respectively distinguishing the flavor of in prescription is crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part, mix 5-10 minute to even;
(3) take by weight Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105233139A (en) * | 2015-11-05 | 2016-01-13 | 农鑫高科（北京）科技开发有限公司 | Traditional Chinese medicinal composition for preventing and treating white scour of piglets, and prevention and treatment method thereof |
| CN105582413A (en) * | 2016-01-20 | 2016-05-18 | 山东迅达康生物科技有限公司 | Pharmaceutical composition for preventing and treating piglet diarrhea and preparation method of pharmaceutical composition |
| CN107898983A (en) * | 2017-11-23 | 2018-04-13 | 贵州长青特种牧业有限责任公司 | A kind of Chinese medicine composition for treating porcupine piglet diarrhea and preparation method thereof |
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| CN1171970A (en) * | 1997-06-26 | 1998-02-04 | 周淑琴 | Health-care wine with antisenility function |
| CN1456074A (en) * | 2003-06-02 | 2003-11-19 | 吴万福 | Sthenic healthy pill carrier pigeon |
| CN101884724A (en) * | 2009-05-13 | 2010-11-17 | 王学文 | Medicinal liquor for treating impotence and preparation method thereof |
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2012
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1171970A (en) * | 1997-06-26 | 1998-02-04 | 周淑琴 | Health-care wine with antisenility function |
| CN1456074A (en) * | 2003-06-02 | 2003-11-19 | 吴万福 | Sthenic healthy pill carrier pigeon |
| CN101884724A (en) * | 2009-05-13 | 2010-11-17 | 王学文 | Medicinal liquor for treating impotence and preparation method thereof |
Non-Patent Citations (6)
| Title |
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| "治仔猪白痢";《甘肃畜牧兽医》编辑部;《甘肃畜牧兽医》;19961231(第6期);第20页 * |
| "治小猪白痢";鹏程;《甘肃畜牧兽医》;20081231(第4期);第16页 * |
| "试论我国高粱产业的发展——四论高粱饲料业的发展";卢庆善 等;《杂粮作物》;20091231;第29卷(第5期);第313页摘要 * |
| 《甘肃畜牧兽医》编辑部."治仔猪白痢".《甘肃畜牧兽医》.1996,(第6期),第20页. |
| 卢庆善 等."试论我国高粱产业的发展——四论高粱饲料业的发展".《杂粮作物》.2009,第29卷(第5期),第313页摘要. |
| 鹏程."治小猪白痢".《甘肃畜牧兽医》.2008,(第4期),第16页. |
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