CN103585461B - Pure Chinese medicine composition for the treatment of poultry organization trichomoniasis and preparation method thereof - Google Patents

Abstract

The present invention relates to a kind of pure Chinese medicine composition for the treatment of poultry organization's trichomoniasis, preparation method is carried out as follows: (1) crosses 700 mesh sieves by after the various compositions in prescription respectively micronizing; (2) take Rhizoma Acori Graminei 15-35 part, Fructus Crataegi 15-35 part, Massa Medicata Fermentata 15-25 part, Pericarpium Citri Reticulatae 15-45 part by weight, mix 5-10 minute to even; (3) take Cortex Magnoliae Officinalis 15-35 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-45 part, Herba Agrimoniae 15-25 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part by weight, mix 5-10 minute to even; (4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and pure Chinese medicine composition is pollution-free, curative effect highly significant, and clinical proof has specially good effect to treatment poultry organization trichomoniasis.

Description

Pure Chinese medicine composition for the treatment of poultry organization trichomoniasis and preparation method thereof

Technical field

The present invention relates to and a kind ofly treat Chinese medicine composition of poultry organization's trichomoniasis and preparation method thereof, belong to field of animal, be particularly a kind ofly specifically designed to pure Chinese medicine composition for the treatment of poultry organization trichomoniasis and preparation method thereof.

Background technology

Poultry organization's trichomoniasis be by poultry organization infusorian parasitize that birds caecum and liver cause to endanger serious a kind of common transmittable to poultry husbandry sick, this disease throughout the year all can be popular, ill chicken with organ hemorrhage, cecitis and hepatitis such as diarrhoea, lassitude, poor appetite, spleen and fabricius bursa for feature, mortality rate can up to 10%-30%, the poultry growth impaired development of recovering, the price of deed declines, and Abwehrkraft des Koepers reduces, easy trouble Other diseases is very large to the harm of poultry.

The pathogen of primary disease is Histomonas meleagridis, is widely distributed.At present, treat this disease the most frequently used be various antibacterials and antiprotozoal drug, as metronidazole, Dimetronidazole etc.; Due to the prolonged and repeated use of these medicines, cause this pathogenic microorganism to create drug resistance to medicine, reduce curative effect, and drug residue in animal body, its product does not reach nuisanceless requirement, have impact on the outlet of poultry product and the health of people.

Therefore research and develop a kind of treat poultry organization's trichomoniasis and have no side effect, the specific medicament of drug residue free is one of this field scientific research technical staff new problem anxious to be resolved.

Summary of the invention

The object of the invention is to overcome above-mentioned weak point, a kind of reasonable recipe is provided, prepare simple, successful, the pure Chinese medicine composition of effectively treating poultry organization's trichomoniasis and preparation method thereof.

Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of poultry organization's trichomoniasis, by following component by weight mixed preparing form: Rhizoma Acori Graminei 15-35 part, Fructus Crataegi 15-35 part, Massa Medicata Fermentata 15-25 part, Pericarpium Citri Reticulatae 15-45 part, Cortex Magnoliae Officinalis 15-35 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-45 part, Herba Agrimoniae 15-25 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part.

Described various component optimum ratio amount is: Rhizoma Acori Graminei 25 parts, Fructus Crataegi 25 parts, Massa Medicata Fermentata 20 parts, Pericarpium Citri Reticulatae 30 parts, Cortex Magnoliae Officinalis 25 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 30 parts, Herba Agrimoniae 20 parts, the Radix Astragali 25 parts, the Rhizoma Atractylodis Macrocephalae 25 parts.

Treat a preparation method for the pure Chinese medicine composition of poultry organization's trichomoniasis, carry out as follows:

(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;

(2) take Rhizoma Acori Graminei 15-35 part, Fructus Crataegi 15-35 part, Massa Medicata Fermentata 15-25 part, Pericarpium Citri Reticulatae 15-45 part by weight, mix 5-10 minute to even;

(3) take Cortex Magnoliae Officinalis 15-35 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-45 part, Herba Agrimoniae 15-25 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.

The medicinal property of each component is as follows:

Rhizoma Acori Graminei: bitter, pungent, warm, GUIXIN, stomach warp, have the function of eliminating phlegm of having one's ideas straightened out, removing dampness to restore normal function of the stomach; Cure mainly the inappetence caused by dampness taste, tripe distention and fullness in the abdomen, have loose bowels, phlegm-damp hoodwinks key clearly, the coma etc. caused by clear YANG failing to ascend.

Fructus Crataegi: sour, sweet, tepor, returns stomach, spleen, Liver Channel, has the function of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis; Cure mainly dyspeptic abdominal flatulence, dyspepsia, prolonged lochia etc.

Massa Medicata Fermentata: sweet, pungent, warm, returns stomach, spleen channel, has invigorating the spleen and regulating the stomach, help digestion the function in adjusting; Cure mainly that food stagnation does not disappear, tripe is swollen, postnatal blood stasis stomachache etc.

Pericarpium Citri Reticulatae: bitter, pungent, warm, returns lung, spleen channel, has the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly poor appetite, stomachache, tripe be swollen, have loose bowels, productive cough due to phlegm-damp etc.

Cortex Magnoliae Officinalis:.

Pseudobulbus Bletillae (Rhizoma Bletillae): bitter, sweet, puckery, be slightly cold, returns liver, lung, stomach warp, has the function of astringing to arrest bleeding, detumescence and promoting granulation, tonifying the lung and stopping cough; Cure mainly lung gastrorrhagia, cough and asthma due to lung deficiency, carbuncle etc.

Herba Agrimoniae: bitter, puckery, flat, GUIXIN, Liver Channel, have the function of astringing to arrest bleeding, dysentery relieving, removing toxic substances; Cure mainly have blood in stool, dysentery, carbuncle sore tumefacting virus.

The Radix Astragali: sweet, tepor, returns spleen, lung meridian, has the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Cure mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficulty burst, burst for a long time and do not hold back.

The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, returns spleen, stomach warp, has the function of invigorating the spleen and replenishing QI, dampness diuretic; Cure mainly diarrhea due to hypofunction of the spleen, edema etc.

All taste Chinese medicine is according to tcm theory compatible combination above, for pathological change and the clinical symptoms of poultry organization's trichomoniasis, mainly according to invigorating the spleen and stomach, regulate the flow of vital energy, stop blooding, the rule for the treatment of of QI invigorating plays therapeutical effect.

The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixing is more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, draws materials wide, curative effect highly significant.According to motherland tradition Chinese veterinarian is theoretical and modern Chinese medicine pharmacology is theoretical, optimize this nine kinds of medicines, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, treatment poultry organization trichomoniasis is had to specially good effect and has no side effect and drug resistance.And make poultry product reach nuisanceless requirement, meet the export standard of poultry product, effectively ensure that people's is healthy.

Detailed description of the invention

Below in conjunction with preferred embodiment, to according to detailed description of the invention provided by the invention, details are as follows:

Embodiment 1

A kind of pure Chinese medicine composition for the treatment of poultry organization's trichomoniasis and preparation method thereof: carry out as follows: (every part by 10g)

(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;

(2) take Rhizoma Acori Graminei 150 parts, Fructus Crataegi 150 parts, Massa Medicata Fermentata 150 parts, Pericarpium Citri Reticulatae 150 parts by weight, mix 5-10 minute to even;

(3) take Cortex Magnoliae Officinalis 150 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 150 parts, Herba Agrimoniae 150 parts, the Radix Astragali 150 parts, the Rhizoma Atractylodis Macrocephalae 150 parts by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.

Embodiment 2

A kind of pure Chinese medicine composition for the treatment of poultry organization's trichomoniasis and preparation method thereof: carry out as follows: (every part by 10g)

(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;

(2) take Rhizoma Acori Graminei 250 parts, Fructus Crataegi 250 parts, Massa Medicata Fermentata 200 parts, Pericarpium Citri Reticulatae 300 parts by weight, mix 5-10 minute to even;

(3) take Cortex Magnoliae Officinalis 250 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 300 parts, Herba Agrimoniae 200 parts, the Radix Astragali 250 parts, the Rhizoma Atractylodis Macrocephalae 250 parts by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.

Embodiment 3

A kind of pure Chinese medicine composition for the treatment of poultry organization's trichomoniasis and preparation method thereof: carry out as follows: (every part by 10g)

(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;

(2) take Rhizoma Acori Graminei 350 parts, Fructus Crataegi 350 parts, Massa Medicata Fermentata 250 parts, Pericarpium Citri Reticulatae 450 parts by weight, mix 5-10 minute to even;

(3) take Cortex Magnoliae Officinalis 350 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 450 parts, Herba Agrimoniae 250 parts, the Radix Astragali 350 parts, the Rhizoma Atractylodis Macrocephalae 350 parts by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.

Clinical trial:

Clinical experiment animal selects 32 ages in days, body weight at 1.5kg-1.6kg, and Laboratory Diagnosed is that the ill broiler of chicken tissues trichomoniasis is tested.Ill chicken isolation raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 100,3 groups of feeding environments are identical, and experimental period carries out 5 days altogether; Blank group is left intact, and drug control group institute's control drug uses treatment by its description; Present composition group by the ill broiler of product of the present invention (compositions obtained by the embodiment of the present invention 1) feeding, day dose be: 450 kilograms are fed or drunk water to every 100 grams of present composition spices 250 kilograms, every day 1-2 time; Reached the object of disease therapy by gastrointestinal absorption after oral.Computational methods: mortality rate=dead animal number/experimental animal number × 100%, cure rate=healing number of animals/experimental animal number × 100%.Following table is the result (testing the 5th day) at the end of experiment.

Table is that the Field information situation that product of the present invention and other medicines treat poultry organization's trichomoniasis contrasts:

Numbering	Group	Mortality rate %	Cure rate %	At the end of have symptom rate %
					I	Blank group	17	66	17
II	Chicken tissues infusorian falls apart group	10	80	10
					III	Chinese medicine composition group of the present invention	4	89	7

This clinical effectiveness statistical analysis, present composition group and chicken tissues infusorian fall apart significant difference (P<0.05) compared with group.

Safety testing:

Choose the healthy broiler 60 of 20 ages in days, according to the made Chinese medicine composition recommended dose of the embodiment of the present invention 1 10 times of spices or drinking-water 5 days, during medication, healthy chicken is without any bad or Deviant Behavior performance, drinking-water of searching for food is normal, and it is not remarkable that body weight increase and blank group (i.e. health not administration group) compare difference.

Above-mentioned detailed description of pure Chinese medicine composition of this treatment poultry organization trichomoniasis and preparation method thereof being carried out with reference to embodiment; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.

Claims (3)

1. treat a pure Chinese medicine composition for poultry organization's trichomoniasis, it is characterized in that by following component by weight mixed preparing form: Rhizoma Acori Graminei 15-35 part, Fructus Crataegi 15-35 part, Massa Medicata Fermentata 15-25 part, Pericarpium Citri Reticulatae 15-45 part, Cortex Magnoliae Officinalis 15-35 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-45 part, Herba Agrimoniae 15-25 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part.

2. the pure Chinese medicine composition for the treatment of poultry organization according to claim 1 trichomoniasis, is characterized in that described various component optimum ratio amount is: Rhizoma Acori Graminei 25 parts, Fructus Crataegi 25 parts, Massa Medicata Fermentata 20 parts, Pericarpium Citri Reticulatae 30 parts, Cortex Magnoliae Officinalis 25 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 30 parts, Herba Agrimoniae 20 parts, the Radix Astragali 25 parts, the Rhizoma Atractylodis Macrocephalae 25 parts.

3. a preparation method for the pure Chinese medicine composition for the treatment of poultry organization according to claim 1 trichomoniasis, is characterized in that carrying out as follows:

(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;

(2) take Rhizoma Acori Graminei 15-35 part, Fructus Crataegi 15-35 part, Massa Medicata Fermentata 15-25 part, Pericarpium Citri Reticulatae 15-45 part by weight, mix 5-10 minute to even;

(3) take Cortex Magnoliae Officinalis 15-35 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-45 part, Herba Agrimoniae 15-25 part, Radix Astragali 15-35 part, Rhizoma Atractylodis Macrocephalae 15-35 part by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.