CN103550391B - Improve pure Chinese medicine composition of laying rate of laying hen and preparation method thereof - Google Patents

Improve pure Chinese medicine composition of laying rate of laying hen and preparation method thereof Download PDF

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CN103550391B
CN103550391B CN201310547796.8A CN201310547796A CN103550391B CN 103550391 B CN103550391 B CN 103550391B CN 201310547796 A CN201310547796 A CN 201310547796A CN 103550391 B CN103550391 B CN 103550391B
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parts
laying
minute
chinese medicine
laying rate
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CN103550391A (en
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周庆福
刘文利
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Ye Yonggang
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The present invention relates to a kind of pure Chinese medicine composition improving laying rate of laying hen, its preparation method carries out as follows: (1) crosses 500 mesh sieves after the various compositions in prescription being carried out respectively micronizing; (2) take Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part by weight, mix 5-10 minute to even; (3) take Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even; (4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, pollution-free, have no side effect, drug residue free; Drastically increase the bioavailability of effective ingredient, also make additive capacity very low, be only 0.2%, well below general tcm product.Clinical proof has specially good effect to raising laying rate of laying hen, and application prospect is boundless.

Description

Improve pure Chinese medicine composition of laying rate of laying hen and preparation method thereof
Technical field
The present invention relates to the pure Chinese medicine composition and preparation method thereof improving laying rate of laying hen, be particularly a kind ofly specifically designed to pure Chinese medicine composition improving laying rate of laying hen and preparation method thereof.
Background technology
Laying rate is the important indicator during laying hen produces, and is the embodiment of laying hen economic benefit quality.Laying rate declines and causes serious economic loss to plant family.Laying rate declines and divides normality laying rate to decline and the decline of abnormalities laying rate, normality laying rate declines and belongs to physiological performance (as the factor such as age in days, kind), and abnormalities laying rate declines and time-sharing environment factor (as illumination, temperature, humidity, noise, stress wait), feed factor (with low quality, calcium phosphorus ration is improper, malnutrition etc.), disease factor etc. (as virosis, bacterial disease, parasitic disease etc.).All there is the problems such as laying rate of laying hen declines or the peak period persistent period is short in present various places, traces it to its cause, mainly relevant with above-mentioned factor.This disease is very large to the harm of breeding layer chicken industry.
The pathogenic factors of primary disease is a lot.This disease almost spreads all over the world nearly 200 countries in six continents, is widely distributed.Because the pathogenic factors of this disease is a lot, so comprehensive prophylactico-therapeutic measures must be taked.At present, this disease caused by disease factor, the most frequently used is Drug therapy, but antiviral drugs (as ribavirin, amantadine, the moroxydine) Ministry of Agriculture prohibites use; Various antibacterials and anti-parasite medicine, due to prolonged and repeated use, cause pathogenic microorganism to which creating drug resistance, reduce curative effect, and drug residue is in animal body with in egg, its quality does not reach nuisanceless requirement, thus have impact on the outlet of poultry product and the healthy of people.
Much employing Chinese medicine is had to improve the product of laying rate of laying hen in the market, but pulverize because its prescription is unreasonable or in Chinese medicine, illegal interpolation Western medicine or product are just simple, particle diameter is excessive, effective ingredient fully can not disengage thus affect its bioavailability, and result of use is not clinically very desirable; Pulverize due to just simple, particle diameter is excessive, and the additive capacity in Clinical practice is very large, how between 1%-5%, not only wastes resource clinical effectiveness but also be not very desirable.
Therefore researching and developing a kind of specific medicament improving laying rate of laying hen is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, a kind of reasonable recipe is provided, preparation is simple, successful, additive capacity are little, effectively improves pure Chinese medicine composition of laying rate of laying hen and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition improving laying rate of laying hen, by following component by weight mixed preparing form: Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part, Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part.
Described various component optimum ratio amount is: the Radix Astragali 20 parts, Herba Leonuri 15 parts, Herba Epimedii 15 parts, Fructus Ligustri Lucidi 20 parts, Radix Isatidis 25 parts, Massa Medicata Fermentata 20 parts, Fructus Capsici 20 parts, 25 parts, Radix Glycyrrhizae.
Improve a preparation method for the pure Chinese medicine composition of laying rate of laying hen, carry out as follows:
(1) the various compositions in prescription are pulverized rear mistake 500 mesh sieve respectively;
(2) take Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part by weight, mix 5-10 minute to even;
(3) take Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
The medicinal property of each component is as follows:
The Radix Astragali: sweet, tepor, returns spleen, lung meridian, has the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Cure mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficulty burst, burst for a long time and do not hold back.
Herba Leonuri: bitter, pungent, be slightly cold, returns liver, pericardium, urinary bladder channel, has the function of promoting blood circulation to restore menstrual flow, inducing diuresis to remove edema; Cure mainly edema oliguria, lochiorrhea, band are inferior.
Herba Epimedii: pungent, sweet, warm, returns liver, kidney channel, has the function of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Cure mainly that waist hip is unable, rheumatic arthralgia, raising immunity etc.
Fructus Ligustri Lucidi: bitter, sweet, cool, returns liver, kidney channel, has the function of liver and kidney tonifying; Cure mainly Light-headedness, soreness of the waist and knees, osteopyrexia and fever etc.
Massa Medicata Fermentata: sweet, pungent, warm, returns stomach, spleen channel, has invigorating the spleen and regulating the stomach, help digestion the function in adjusting; Cure mainly that food stagnation does not disappear, tripe is swollen, postnatal blood stasis stomachache etc.
Radix Glycyrrhizae: sweet, flat, returns lung, the heart, spleen channel, has invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Fructus Capsici: pungent, hot, GUIXIN, spleen channel, have the function of warming spleen and stomach for dispelling cold, appetite-stimulating indigestion-relieving, antipyretic-antalgic; Cure mainly cold stagnant stomachache, Deficiency and coldness of spleen and stomach, Common Cold, arthralgia etc.
Radix Isatidis: bitter, cold, GUIXIN, stomach warp, have the function of heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving; Cure mainly anemopyretic cold, laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison etc.
All herbal medicines are according to the theoretical compatible combination of Chinese veterinarian above, and the various factors reduced for causing laying rate of laying hen, plays the comprehensive function for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixing is more even; This compositions is pollution-free, no drug residue, and cost is low, draws materials wide, curative effect highly significant.Optimize this eight kinds of medicines according to motherland's Chinese veterinarian's traditional theory, and make them form said composition according to optimum ratio, clinical practice proves, has specially good effect to raising laying rate of laying hen.And make quality of poultry eggs reach nuisanceless requirement, reach the export standard of poultry egg products, effectively ensure that people's is healthy.
Preparation technology adopts advanced superfine communication technique, the effective ingredient of medical material is fully discharged fast, drastically increases the bioavailability of effective ingredient, also make additive capacity very low, be only 0.2%, well below general tcm product.Clinical proof has specially good effect to raising laying rate of laying hen, and application prospect is boundless.
Detailed description of the invention
Below in conjunction with preferred embodiment, to according to detailed description of the invention provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition improving laying rate of laying hen and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized rear mistake 500 mesh sieve respectively;
(2) take the Radix Astragali 150 parts, Herba Leonuri 100 parts, Herba Epimedii 100 parts, Fructus Ligustri Lucidi 150 parts by weight, mix 5-10 minute to even;
(3) take Radix Isatidis 150 parts, Massa Medicata Fermentata 150 parts, Fructus Capsici 150 parts, 150 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition improving laying rate of laying hen and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized rear mistake 500 mesh sieve respectively;
(2) take the Radix Astragali 200 parts, Herba Leonuri 150 parts, Herba Epimedii 150 parts, Fructus Ligustri Lucidi 200 parts by weight, mix 5-10 minute to even;
(3) take Radix Isatidis 250 parts, Massa Medicata Fermentata 200 parts, Fructus Capsici 200 parts, 250 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition improving laying rate of laying hen and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized rear mistake 500 mesh sieve respectively;
(2) take the Radix Astragali 250 parts, Herba Leonuri 250 parts, Herba Epimedii 150 parts, Fructus Ligustri Lucidi 250 parts by weight, mix 5-10 minute to even;
(3) take Radix Isatidis 350 parts, Massa Medicata Fermentata 250 parts, Fructus Capsici 250 parts, 350 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Clinical trial:
Clinical experiment animal selects the Roman egghen that 150 age in days laying rate are low.Experimental chicken isolation raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 100,3 groups of feeding environments are identical, and experimental period carries out 10 days altogether; Blank group is left intact, and drug control group institute's control drug uses treatment by its description; Present composition group can by product of the present invention (compositions obtained by the embodiment of the present invention 1) feeding, and usage and dosage is: this product by every 100g spice 50kg, every day 2 ~ 3 times.Reached the object improving laying rate by gastrointestinal absorption after oral.Computational methods: on average every day, laying rate %=respectively organized egg production/each group chicken number × natural law × 100%.Result when following table is experiment the 10th day.
Table is that the Field information situation that the present invention and other medicines improve laying rate of laying hen contrasts:
Numbering Group Laying rate %
I Blank group 27
II The precious group of laying hen 38
III Present composition group 48
Clinical effectiveness statistical analysis, present composition group is difference extremely remarkable (P < 0.01) compared with the precious group of laying hen.
Safety testing:
Choose the healthy Roman egghen 60 of 70 ages in days, 5 times of spices according to the made compositions recommended dose of the embodiment of the present invention 1 are fed 10 days, and during medication, observation experiment chicken is without any bad or Deviant Behavior performance, and drinking-water of searching for food is normal.
Above-mentioned detailed description of pure Chinese medicine composition of this raising laying rate of laying hen and preparation method thereof being carried out with reference to embodiment; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.

Claims (3)

1. improve a pure Chinese medicine composition for laying rate of laying hen, it is characterized in that by following component by weight mixed preparing form: Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part, Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part.
2. the pure Chinese medicine composition of raising laying rate of laying hen according to claim 1, it is characterized in that by following component by weight mixed preparing form: the Radix Astragali 20 parts, Herba Leonuri 15 parts, Herba Epimedii 15 parts, Fructus Ligustri Lucidi 20 parts, Radix Isatidis 25 parts, Massa Medicata Fermentata 20 parts, Fructus Capsici 20 parts, 25 parts, Radix Glycyrrhizae.
3. a preparation method for the pure Chinese medicine composition of raising laying rate of laying hen according to claim 1, is characterized in that carrying out as follows:
(1) the various compositions in prescription are pulverized rear mistake 500 mesh sieve respectively;
(2) take Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part by weight, mix 5-10 minute to even;
(3) take Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
CN201310547796.8A 2013-10-31 2013-10-31 Improve pure Chinese medicine composition of laying rate of laying hen and preparation method thereof Expired - Fee Related CN103550391B (en)

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105533147A (en) * 2015-12-04 2016-05-04 聂向会 Green feed capable of improving laying rate of laying hens
CN105535700A (en) * 2016-01-18 2016-05-04 山东迅达康生物科技有限公司 Medicinal composition for improving laying rate and hatching rate of laying poultry and breeding poultry, and preparation method thereof
CN110393753A (en) * 2019-08-28 2019-11-01 安徽农业大学 A kind of Chinese medicine composition and preparation method for preventing and treating Egg Production of Laying Hens syndrome

Citations (2)

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Publication number Priority date Publication date Assignee Title
CN101658246A (en) * 2009-08-26 2010-03-03 王直军 Chinese medicinal feed additive for improving laying rate of layer chickens
CN101670021A (en) * 2009-09-17 2010-03-17 天津生机集团股份有限公司 Traditional Chinese medicine composite for treating egg laying performance reduction of layer and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658246A (en) * 2009-08-26 2010-03-03 王直军 Chinese medicinal feed additive for improving laying rate of layer chickens
CN101670021A (en) * 2009-09-17 2010-03-17 天津生机集团股份有限公司 Traditional Chinese medicine composite for treating egg laying performance reduction of layer and preparation method thereof

Non-Patent Citations (3)

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Title
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中草药饲料添加剂促进畜禽生长性能研究现状及展望;朴香淑等;《饲料工业》;20020217;第23卷(第01期);12-15 *
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GR01 Patent grant
CB03 Change of inventor or designer information

Inventor after: Wu Xianshi

Inventor after: Wu Jiafeng

Inventor after: Zhang Wenxue

Inventor before: Zhou Qingfu

Inventor before: Liu Wenli

CB03 Change of inventor or designer information
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20180323

Address after: 201507 Jinshan District, Caojing Town, Jinshan District, Shanghai, No. 7 and 8

Patentee after: SHANGHAI HOWELL BIO-TECH CO.,LTD.

Address before: 266000 Shandong Province, Qingdao city Licang District Nanwang Industrial Park No. 66

Patentee before: QINGDAO LVMAN BIOLOGICAL ENGINEERING Co.,Ltd.

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20200601

Address after: 10 households, No. 81, Liuxiang, Xinghualing District, Taiyuan City, Shanxi Province

Patentee after: Ye Yonggang

Address before: 201507 Jinshan District, Caojing Town, Jinshan District, Shanghai, No. 7 and 8

Patentee before: SHANGHAI HOWELL BIO-TECH Co.,Ltd.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160427

Termination date: 20211031