CN103550391A - Pure traditional Chinese medicine composition for increasing laying rate of laying hens and preparation method of composition - Google Patents

Pure traditional Chinese medicine composition for increasing laying rate of laying hens and preparation method of composition Download PDF

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Publication number
CN103550391A
CN103550391A CN201310547796.8A CN201310547796A CN103550391A CN 103550391 A CN103550391 A CN 103550391A CN 201310547796 A CN201310547796 A CN 201310547796A CN 103550391 A CN103550391 A CN 103550391A
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chinese medicine
laying
medicine composition
traditional chinese
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CN201310547796.8A
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CN103550391B (en
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周庆福
刘文利
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Ye Yonggang
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention relates to a pure traditional Chinese medicine composition for increasing the laying rate of laying hens. A preparation method for the pure traditional Chinese medicine composition comprises the following steps: (1) carrying out superfine grinding on various ingredients in a formula, and passing a sieve with 500 meshes; (2) weighing the following materials in parts by weight: 15-25 parts of astragalus membranaceus, 10-25 parts of motherwort, 10-15 parts of herba epimedii and 15-25 parts of glossy privet fruits, and mixing for 5-10 minutes until the materials are uniformly mixed; (3) weighing the following materials in parts by weight: 15-35 parts of radix isatidis, 15-25 parts of medicated leaven, 15-25 parts of red peppers and 15-35 parts of liquorice, and mixing for 5-10 minutes until the materials are uniformly mixed; and (4) combining mixtures in the steps (2) and (3), and continuously mixing for 10-15 minutes until the mixtures are uniformly mixed. The pure traditional Chinese medicine composition has the beneficial effects of being reasonable in formula, easy to prepare and free from pollution and toxic and side effects; the bioavailability of effective ingredients is greatly increased, and the addition amount is greatly reduced and is only 0.2% which is far below than that of a general traditional Chinese medicine product; a clinical test proves that the pure traditional Chinese medicine composition has a special effect of increasing the laying rate of the laying lens and has a very wide application prospect.

Description

Improve pure Chinese medicine composition of laying rate of laying hen and preparation method thereof
Technical field
The present invention relates to pure Chinese medicine composition improving laying rate of laying hen and preparation method thereof, particularly a kind of pure Chinese medicine composition that is specifically designed to raising laying rate of laying hen and preparation method thereof.
Background technology
Laying rate is the important indicator during laying hen produces, and is the embodiment of laying hen economic benefit quality.Laying rate declines and causes serious economic loss to plant family.Laying rate declines, and minute normality laying rate declines and improper property laying rate declines, normality laying rate declines and to belong to physiological performance (as factors such as age in days, kinds), and improper property laying rate declines and time-sharing environment factor (as illumination, temperature, humidity, noise, stress wait), feed factor (with low quality, calcium phosphorus ration is improper, malnutrition etc.), disease factor etc. (as virosis, bacterial disease, parasitic disease etc.).Now the problem such as the peak period persistent period is short all appears that laying rate of laying hen declines or in various places, trace it to its cause, and be mainly relevant with above-mentioned factor.This disease is very large to the harm of breeding layer chicken industry.
The pathogenic factors of primary disease is a lot.Almost spread all over the world nearly 200 countries in six continents of this disease, are widely distributed.Because this sick pathogenic factors is a lot, so must take comprehensive prophylactico-therapeutic measures.At present, this disease being caused by disease factor, the most frequently used is Drug therapy, but antiviral drugs (as ribavirin, amantadine, the moroxydine) Ministry of Agriculture has prohibited use; Various antibacterials and anti-parasite medicine, due to prolonged and repeated use, cause pathogenic microorganism to produce drug resistance to it, reduced curative effect, and drug residue in animal body with egg in, its quality does not reach nuisanceless requirement, thereby has affected the healthy of the outlet of poultry product and people.
There is in the market much employing Chinese medicine to improve the product of laying rate of laying hen, but due to its prescription is unreasonable or Chinese medicine in illegal add just simple pulverizing of Western medicine or product, particle diameter is excessive, thereby effective ingredient can not fully disengage, affect its bioavailability, result of use is not clinically very desirable; Due to simple pulverizing just, particle diameter is excessive, and the additive capacity in clinical use is very large, how, between 1%-5%, has not only wasted resource clinical effectiveness but also be not very desirable.
Therefore researching and developing a kind of specific medicament that improves laying rate of laying hen is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, additive capacity be little, effectively improves pure Chinese medicine composition of laying rate of laying hen and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition that improves laying rate of laying hen, by following component by weight mixed preparing form: Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part, Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part.
Described various component optimum ratio amount is: 20 parts of the Radixs Astragali, 15 parts of Herba Leonuris, 15 parts of Herba Epimedii, 20 parts of Fructus Ligustri Lucidi, 25 parts of Radix Isatidis, 20 parts of Massa Medicata Fermentata, 20 parts of Fructus Capsicis, 25 parts, Radix Glycyrrhizae.
A preparation method for the pure Chinese medicine composition of laying rate of laying hen, carry out as follows:
(1) the various compositions in prescription are pulverized respectively to rear mistake 500 mesh sieves;
(2) take by weight Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part, mix 5-10 minute to even;
(3) take by weight Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
The Radix Astragali: sweet, tepor, return spleen, lung meridian, there is the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
Herba Leonuri: bitter, pungent, be slightly cold, return liver, pericardium, urinary bladder channel, there is the function of promoting blood circulation to restore menstrual flow, inducing diuresis to remove edema; Cure mainly edema oliguria, lochiorrhea, be with inferior.
Herba Epimedii: pungent, sweet, warm, return liver, kidney channel, there is the function of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Cure mainly that waist hip is unable, rheumatic arthralgia, raising immunity etc.
Fructus Ligustri Lucidi: bitter, sweet, cool, return liver, kidney channel, there is the function of liver and kidney tonifying; Cure mainly Light-headedness, soreness of the waist and knees, osteopyrexia and fever etc.
Massa Medicata Fermentata: sweet, pungent, warm, return stomach, spleen channel, the function that there is invigorating the spleen and regulating the stomach, helps digestion in adjusting; Cure mainly that food stagnation does not disappear, tripe is swollen, postnatal blood stasis stomachache etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Fructus Capsici: pungent, hot, GUIXIN, spleen channel, have the function of warming spleen and stomach for dispelling cold, appetite-stimulating indigestion-relieving, antipyretic-antalgic; Cure mainly cold stagnant stomachache, Deficiency and coldness of spleen and stomach, Common Cold, arthralgia etc.
Radix Isatidis: bitter, cold, GUIXIN, stomach warp, have the function of heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving; Cure mainly anemopyretic cold, laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison etc.
All herbal medicines, according to the theoretical compatible combination of Chinese veterinarian, for the various factors that causes that laying rate of laying hen reduces, are brought into play the comprehensive function for the treatment of both the principal and secondary aspects of a disease above.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; This compositions is pollution-free, no drug residue, and cost is low, draws materials wide, curative effect highly significant.According to motherland's Chinese veterinarian's traditional theory, optimize this eight kinds of medicines, and make them according to optimum ratio, form said composition, clinical practice proves there is specially good effect to improving laying rate of laying hen.And make quality of poultry eggs reach nuisanceless requirement, reached the export standard of fowl egg products, effectively guaranteed that people's is healthy.
In preparation technology, adopting advanced superfine communication technique, the effective ingredient of medical material is fully discharged fast, greatly improved the bioavailability of effective ingredient, also make additive capacity very low, is only 0.2%, well below general tcm product.Clinical proof has specially good effect to improving laying rate of laying hen, and application prospect is boundless.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition that improves laying rate of laying hen and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized respectively to rear mistake 500 mesh sieves;
(2) take by weight 150 parts of the Radixs Astragali, 100 parts of Herba Leonuris, 100 parts of Herba Epimedii, 150 parts of Fructus Ligustri Lucidi, mix 5-10 minute to even;
(3) take by weight 150 parts of Radix Isatidis, 150 parts of Massa Medicata Fermentata, 150 parts of Fructus Capsicis, 150 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition that improves laying rate of laying hen and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized respectively to rear mistake 500 mesh sieves;
(2) take by weight 200 parts of the Radixs Astragali, 150 parts of Herba Leonuris, 150 parts of Herba Epimedii, 200 parts of Fructus Ligustri Lucidi, mix 5-10 minute to even;
(3) take by weight 250 parts of Radix Isatidis, 200 parts of Massa Medicata Fermentata, 200 parts of Fructus Capsicis, 250 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition that improves laying rate of laying hen and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized respectively to rear mistake 500 mesh sieves;
(2) take by weight 250 parts of the Radixs Astragali, 250 parts of Herba Leonuris, 150 parts of Herba Epimedii, 250 parts of Fructus Ligustri Lucidi, mix 5-10 minute to even;
(3) take by weight 350 parts of Radix Isatidis, 250 parts of Massa Medicata Fermentata, 250 parts of Fructus Capsicis, 350 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
Clinical experiment animal is selected the Luo Man laying hen that 150 age in days laying rate are low.Experimental chicken isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 100 every group, 3 groups of feeding environments are identical, and experimental period is carried out 10 days altogether; Blank group is left intact, and medicine matched group is used treatment by institute's control drug by its description; Present composition group can be by product of the present invention (the prepared compositions of the embodiment of the present invention 1) feeding, and usage and dosage is: this product is by every 100g spice 50kg, every day 2~3 times.After oral, by gastrointestinal absorption, reach the object that improves laying rate.Computational methods: average every day, laying rate %=respectively organized egg production/respectively organize chicken number * natural law * 100%.Following table is the result of experiment in the time of the 10th day.
Table is the field applicable cases contrast that the present invention and other medicines improve laying rate of laying hen:
Numbering Group Laying rate %
I Blank group 27
II The precious group of laying hen 38
III Present composition group 48
Clinical effectiveness statistical analysis, present composition group is compared difference extremely significantly (P < 0.01) with the precious group of laying hen.
Safety testing:
Choose 60 of the healthy Luo Man laying hens of 70 ages in days, according to 5 times of spices of the made compositions recommended dose of the embodiment of the present invention 1, feed 10 days, during medication, observation experiment chicken is without any bad or Deviant Behavior performance, and the drinking-water of searching for food is normal.
Above-mentioned detailed description of pure Chinese medicine composition of this raising laying rate of laying hen and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.

Claims (3)

1. improve a pure Chinese medicine composition for laying rate of laying hen, it is characterized in that by following component by weight mixed preparing form: Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part, Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part.
2. the pure Chinese medicine composition of raising laying rate of laying hen according to claim 1, it is characterized in that by following component by weight mixed preparing form: 20 parts of the Radixs Astragali, 15 parts of Herba Leonuris, 15 parts of Herba Epimedii, 20 parts of Fructus Ligustri Lucidi, 25 parts of Radix Isatidis, 20 parts of Massa Medicata Fermentata, 20 parts of Fructus Capsicis, 25 parts, Radix Glycyrrhizae.
3. a preparation method for the pure Chinese medicine composition of raising laying rate of laying hen according to claim 1 and 2, is characterized in that carrying out as follows:
(1) the various compositions in prescription are pulverized respectively to rear mistake 500 mesh sieves;
(2) take by weight Radix Astragali 15-25 part, Herba Leonuri 10-25 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 15-25 part, mix 5-10 minute to even;
(3) take by weight Radix Isatidis 15-35 part, Massa Medicata Fermentata 15-25 part, Fructus Capsici 15-25 part, Radix Glycyrrhizae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
CN201310547796.8A 2013-10-31 2013-10-31 Improve pure Chinese medicine composition of laying rate of laying hen and preparation method thereof Expired - Fee Related CN103550391B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105533147A (en) * 2015-12-04 2016-05-04 聂向会 Green feed capable of improving laying rate of laying hens
CN105535700A (en) * 2016-01-18 2016-05-04 山东迅达康生物科技有限公司 Medicinal composition for improving laying rate and hatching rate of laying poultry and breeding poultry, and preparation method thereof
CN110393753A (en) * 2019-08-28 2019-11-01 安徽农业大学 A kind of Chinese medicine composition and preparation method for preventing and treating Egg Production of Laying Hens syndrome

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658246A (en) * 2009-08-26 2010-03-03 王直军 Chinese medicinal feed additive for improving laying rate of layer chickens
CN101670021A (en) * 2009-09-17 2010-03-17 天津生机集团股份有限公司 Traditional Chinese medicine composite for treating egg laying performance reduction of layer and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658246A (en) * 2009-08-26 2010-03-03 王直军 Chinese medicinal feed additive for improving laying rate of layer chickens
CN101670021A (en) * 2009-09-17 2010-03-17 天津生机集团股份有限公司 Traditional Chinese medicine composite for treating egg laying performance reduction of layer and preparation method thereof

Non-Patent Citations (3)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105533147A (en) * 2015-12-04 2016-05-04 聂向会 Green feed capable of improving laying rate of laying hens
CN105535700A (en) * 2016-01-18 2016-05-04 山东迅达康生物科技有限公司 Medicinal composition for improving laying rate and hatching rate of laying poultry and breeding poultry, and preparation method thereof
CN110393753A (en) * 2019-08-28 2019-11-01 安徽农业大学 A kind of Chinese medicine composition and preparation method for preventing and treating Egg Production of Laying Hens syndrome

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Legal Events

Date Code Title Description
CB03 Change of inventor or designer information

Inventor after: Wu Xianshi

Inventor after: Wu Jiafeng

Inventor after: Zhang Wenxue

Inventor before: Zhou Qingfu

Inventor before: Liu Wenli

TR01 Transfer of patent right

Effective date of registration: 20180323

Address after: 201507 Jinshan District, Caojing Town, Jinshan District, Shanghai, No. 7 and 8

Patentee after: SHANGHAI HOWELL BIO-TECH CO.,LTD.

Address before: 266000 Shandong Province, Qingdao city Licang District Nanwang Industrial Park No. 66

Patentee before: QINGDAO LVMAN BIOLOGICAL ENGINEERING Co.,Ltd.

TR01 Transfer of patent right

Effective date of registration: 20200601

Address after: 10 households, No. 81, Liuxiang, Xinghualing District, Taiyuan City, Shanxi Province

Patentee after: Ye Yonggang

Address before: 201507 Jinshan District, Caojing Town, Jinshan District, Shanghai, No. 7 and 8

Patentee before: SHANGHAI HOWELL BIO-TECH Co.,Ltd.

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160427

Termination date: 20211031