CN102727694B - Compound propolis composition used for treating broiler ascites syndrome, and preparation method thereof - Google Patents

Compound propolis composition used for treating broiler ascites syndrome, and preparation method thereof Download PDF

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Publication number
CN102727694B
CN102727694B CN201210204225.XA CN201210204225A CN102727694B CN 102727694 B CN102727694 B CN 102727694B CN 201210204225 A CN201210204225 A CN 201210204225A CN 102727694 B CN102727694 B CN 102727694B
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parts
pericarpium citri
composition
semen
propolis
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CN102727694A (en
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周庆福
刘文利
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Qingdao Lvman Bioengineering Co Ltd
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention relates to a compound propolis composition used for treating broiler ascites syndrome. The composition is prepared from the mixed components of, by weight: 15-30 parts of propolis, 10-30 parts of rhubarb, 15-35 parts of immature tangerine fruit, 15-45 parts of seasoned orange peel, 15-35 parts of agaric, 10-35 parts of betelnutpalm seed, 15-35 parts of submature bitter orange, 15-35 parts of garden radish seed, 15-35 parts of swordlike atractylodes rhizome, 5-15 parts of radix phytolaccae, 15-35 parts of fringed pind herb, 15-35 parts of polygonum aviculare, 15-35 parts of cape jasmine, and 15-45 parts of licorice root. The composition provided by the invention is advantaged in reasonable formula, simple preparation, pure traditional Chinese composition and no pollution, no toxic or side effect, no drug residue, and substantial curative effect. As a result of clinical application, the composition has a special effect in treating broiler ascites syndrome.

Description

Compound bee-glue composition for the treatment of broiler ascites syndrome and preparation method thereof
Technical field
The present invention relates to a kind of compound bee-glue composition for the treatment of broiler ascites syndrome and preparation method thereof, belong to animal field of medicaments, particularly a kind of compound bee-glue composition that is specifically designed to treatment broiler ascites syndrome and preparation method thereof.
Background technology
Broiler ascites syndrome is a kind of common disease that mainly betides broiler chicken, and primary disease is distributed widely in all over the world, is gathered into too much ascites with serosity liquid, pulmonary venous pleonaemia edema, and cardiac dilatation, hypertrophy, hepatic lesions is feature.Fast large-scale broiler sickness rate with age in 2-3 week is the highest.This disease all can occur throughout the year, and mortality rate is between 1%-85%, very large to the harm of broiler chicken.Concrete predisposing factors it is generally acknowledged that pathogeny is relevant with its pulmonary hypertension with heredity, anoxia is relevant with feed factor.
At present, this disease does not also have good Therapeutic Method, and just in feedstuff, adding vitamin, aminoacid etc. prevents primary disease.Once poultry morbidity, medicine is not treated effectively, causes very large loss to broiler industry.
Therefore research and develop a kind of treat broiler ascites syndrome and have no side effect, the specific medicament of drug residue free is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide a kind of reasonable recipe, preparation simple, have no side effect, drug residue free, successful, effectively treat compound bee-glue composition of broiler ascites syndrome and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of compound bee-glue composition for the treatment of broiler ascites syndrome, by following component by weight mixed preparing form: propolis 15-30 part, Radix Et Rhizoma Rhei 10-30 part, Pericarpium Citri Reticulatae Viride 15-35 part, Pericarpium Citri Reticulatae 15-45 part, Polyporus 15-35 part, Semen Arecae 10-35 part, Fructus Aurantii 15-35 part, Semen Raphani 15-35 part, Rhizoma Atractylodis 15-35 part, trade route 5-15 part, Herba Dianthi 15-35 part, Herba Polygoni Avicularis 15-35 part, Fructus Gardeniae 15-35 part, Radix Glycyrrhizae 15-45 part.
Described various component optimum ratio amount is: 20 parts of propolis, 20 parts of Radix Et Rhizoma Rhei, 25 parts, Pericarpium Citri Reticulatae Viride, 30 parts of Pericarpium Citri Reticulataes, 25 parts of Polyporus, 20 parts of Semen Arecaes, 25 parts of Fructus Aurantiis, 25 parts of Semen Raphanis, 25 parts of Rhizoma Atractylodis, 10 parts, trade route, 25 parts of Herba Dianthis, 25 parts of Herba Polygoni Avicularis, 25 parts of Fructus Gardeniaes, 30 parts, Radix Glycyrrhizae.
Treat a preparation method for the compound bee-glue composition of broiler ascites syndrome, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight propolis 15-30 part, Radix Et Rhizoma Rhei 10-30 part, Pericarpium Citri Reticulatae Viride 15-35 part, Pericarpium Citri Reticulatae 15-45 part, Polyporus 15-35 part, Semen Arecae 10-35 part, Fructus Aurantii 15-35 part, mix 5-10 minute to even;
(3) take by weight Semen Raphani 15-35 part, Rhizoma Atractylodis 15-35 part, trade route 5-15 part, Herba Dianthi 15-35 part, Herba Polygoni Avicularis 15-35 part, Fructus Gardeniae 15-35 part, Radix Glycyrrhizae 15-45 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Propolis: bitter, acrid, cold, return spleen, lung, stomach warp, there is anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic is oxidized, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.
Radix Et Rhizoma Rhei: bitter, cold, return large intestine, spleen, stomach, liver, pericardium channel, there is the function of purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, removing mass blood stasis expelling; Cure mainly excess-heat constipation, combined symptoms, the yellow furunculosis of skin ulcer, conjunctival congestion and swelling pain, enteritis etc.
Pericarpium Citri Reticulatae Viride: bitter, pungent, warm, return liver, gallbladder, stomach warp, there is soothing the liver dispelling the stagnated QI, the stagnant function of removing food stagnancyization; Cure mainly chest and abdomen swelling and pain, flatulence, accumulation of food in the stomach and intes tine due to indigestion, QI and blood pent-up, acute mastitis etc.
Pericarpium Citri Reticulatae: bitter, pungent, warm, return lung, spleen channel, there is the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly poor appetite, stomachache, tripe is swollen, have loose bowels, productive cough due to phlegm-damp etc.
Polyporus: sweet, light, flat, return kidney, urinary bladder channel, there is the function of eliminating dampness and diuresis; Cure mainly dysuria, edema, have loose bowels, stranguria with turbid discharge, be with inferior.
Semen Arecae: bitter, pungent, warm, return stomach, large intestine channel, there is the function of anthelmintic, removing food stagnancy, circulation of qi promoting, diuretic; Cure mainly taeniasis, the impaction of rumen, dyspeptic abdominal distention, constipation, edema etc.
Fructus Aurantii: bitter, pungent, sour, warm, return stomach, spleen channel, the function that there is promoting the circulation of QI to alleviate the stagnation in middle-JIAO, reduce phlegm, helps digestion; Cure mainly that dyspepsia does not disappear, tripe is swollen, feces is dry, hang down de-disease, the stagnant vapour lock of expectorant etc.
Semen Raphani: sweet, pungent, flat, return lung, spleen, stomach warp, there is the function of dyspepsia and intestinal stasis relieving, lowering the adverse-rising QI to resolve phlegm; Cure mainly stagnation of QI food stagnation, abdominal distention, phlegm retention cough with asthma etc.
Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach, Liver Channel, there is the function of drying damp and strengthening spleen, expelling wind and cold, improving eyesight; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold, nyctalopia etc.
Trade route: bitter, cold, return kidney, spleen, large intestine channel, there is the detumescence of relieving oedema or abdominal distension through diuresis or purgation, tonneau two function just; Cure mainly retained water and stop umbilicus, edema, constipation and anuresis etc.
Herba Dianthi: bitter, cold, GUIXIN, small intestine meridian, have the function that inducing diuresis for treating stranguria syndrome, removing blood stasis stimulate the menstrual flow; Cure mainly pyretic stranguria, stranguria with blood, difficulty in urination etc.
Herba Polygoni Avicularis: bitter, be slightly cold, return urinary bladder channel, there is inducing diuresis for treating stranguria syndrome, parasite killing, antipruritic function; Cure mainly that pyretic stranguria, short urination are red, jaundice due to damp-heat, eczema etc.
Fructus Gardeniae: bitter, cold, GUIXIN, lung, tri-jiao channel, have the function of eliminating fire and detoxication, clearing away heat and promoting diuresis, removing heat from blood; Cure mainly three warmers intenseness of heat, jaundice due to damp-heat, pyretic stranguria, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, heat in blood epistaxis etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
All taste Chinese medicine, according to tcm theory compatible combination, for paathogenic factor and the pathological change of broiler ascites syndrome, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease above.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, draws materials wide, curative effect highly significant.According to the tradition Chinese veterinarian of motherland, theoretical and modern Chinese medicine pharmacology theory, optimizes this 14 kinds of medicines, and makes them form pure Chinese powder medicine according to optimum ratio, and clinical practice proves that treatment broiler ascites syndrome is had specially good effect and had no side effect and drug resistance.And make poultry product reach nuisanceless requirement, meet the export standard of poultry product, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of compound bee-glue composition for the treatment of broiler ascites syndrome and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 150 parts of propolis, 100 parts of Radix Et Rhizoma Rhei, 150 parts, Pericarpium Citri Reticulatae Viride, 150 parts of Pericarpium Citri Reticulataes, 150 parts of Polyporus, 100 parts of Semen Arecaes, 150 parts of Fructus Aurantiis, mix 5-10 minute to even;
(3) take by weight 150 parts of Semen Raphanis, 150 parts of Rhizoma Atractylodis, 50 parts, trade route, 150 parts of Herba Dianthis, 150 parts of Herba Polygoni Avicularis, 150 parts of Fructus Gardeniaes, 150 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition for the treatment of broiler ascites syndrome and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 200 parts of propolis, 200 parts of Radix Et Rhizoma Rhei, 250 parts, Pericarpium Citri Reticulatae Viride, 300 parts of Pericarpium Citri Reticulataes, 250 parts of Polyporus, 150 parts of Semen Arecaes, 250 parts of Fructus Aurantiis, mix 5-10 minute to even;
(3) take by weight 250 parts of Semen Raphanis, 250 parts of Rhizoma Atractylodis, 100 parts, trade route, 250 parts of Herba Dianthis, 250 parts of Herba Polygoni Avicularis, 250 parts of Fructus Gardeniaes, 300 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition for the treatment of broiler ascites syndrome and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight 300 parts of propolis, 300 parts of Radix Et Rhizoma Rhei, 350 parts, Pericarpium Citri Reticulatae Viride, 450 parts of Pericarpium Citri Reticulataes, 350 parts of Polyporus, 350 parts of Semen Arecaes, 350 parts of Fructus Aurantiis, mix 5-10 minute to even;
(3) take by weight 350 parts of Semen Raphanis, 350 parts of Rhizoma Atractylodis, 150 parts, trade route, 350 parts of Herba Dianthis, 350 parts of Herba Polygoni Avicularis, 350 parts of Fructus Gardeniaes, 450 parts, Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
Clinical experiment animal selects 18 ages in days, body weight at 1.2kg-1.5kg, the ill broiler that Laboratory Diagnosed is broiler ascites syndrome.Ill chicken isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 60 every group, 3 groups of feeding environments are identical, and experimental period is carried out 5 days altogether; Blank group is left intact, and medicine matched group uses treatment by institute's control drug by its description; Chinese medicine composition group of the present invention is the ill poultry of product feeding of the present invention, and a day dose is: 500 kilograms are fed or drunk water to 280 kilograms of every 100 grams of present composition spices, every day 1-2 time; After oral, reach the object for the treatment of disease by gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number × 100%, cure rate=healing number of animals/experimental animal number × 100%.Result (testing the 5th day) when following table is experiment end.
Table is the field applicable cases contrast of the present invention and other medicines treatment broiler ascites syndrome:
Numbering Group Mortality rate % Cure rate % When end, there is symptom rate %
I Blank group 20.0 63.3 16.7
II Ascites dissipation group 8.3 81.7 10.0
III Chinese medicine composition group of the present invention 5.0 88.3 6.7
This clinical effectiveness statistical analysis, present composition group and ascites dissipation group significant difference (P < 0.05) compared with aspect cure rate.
Safety testing:
Choose 60 of 20 age in days healthy AA broiler, according to 10 times of spices of the made Chinese medicine composition recommended dose of the embodiment of the present invention 1 or drinking-water 5 days, during medication, healthy chicken is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and body weight increases that to compare difference not remarkable with blank group (being not administration of health group).
The above-mentioned detailed description that compound bee-glue composition to this treatment broiler ascites syndrome and preparation method thereof carries out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.

Claims (3)

1. treat a compound bee-glue composition for broiler ascites syndrome, it is characterized in that by following component by weight mixed preparing form: propolis 15-30 part, Radix Et Rhizoma Rhei 10-30 part, Pericarpium Citri Reticulatae Viride 15-35 part, Pericarpium Citri Reticulatae 15-45 part, Polyporus 15-35 part, Semen Arecae 10-35 part, Fructus Aurantii 15-35 part, Semen Raphani 15-35 part, Rhizoma Atractylodis 15-35 part, trade route 5-15 part, Herba Dianthi 15-35 part, Herba Polygoni Avicularis 15-35 part, Fructus Gardeniae 15-35 part, Radix Glycyrrhizae 15-45 part.
2. the compound bee-glue composition for the treatment of broiler ascites syndrome according to claim 1, it is characterized in that by following component by weight mixed preparing form: 20 parts of propolis, 20 parts of Radix Et Rhizoma Rhei, 25 parts, Pericarpium Citri Reticulatae Viride, 30 parts of Pericarpium Citri Reticulataes, 25 parts of Polyporus, 20 parts of Semen Arecaes, 25 parts of Fructus Aurantiis, 25 parts of Semen Raphanis, 25 parts of Rhizoma Atractylodis, 10 parts, trade route, 25 parts of Herba Dianthis, 25 parts of Herba Polygoni Avicularis, 25 parts of Fructus Gardeniaes, 30 parts, Radix Glycyrrhizae.
3. a preparation method for the compound bee-glue composition for the treatment of broiler ascites syndrome according to claim 1, is characterized in that carrying out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take by weight propolis 15-30 part, Radix Et Rhizoma Rhei 10-30 part, Pericarpium Citri Reticulatae Viride 15-35 part, Pericarpium Citri Reticulatae 15-45 part, Polyporus 15-35 part, Semen Arecae 10-35 part, Fructus Aurantii 15-35 part, mix 5-10 minute to even;
(3) take by weight Semen Raphani 15-35 part, Rhizoma Atractylodis 15-35 part, trade route 5-15 part, Herba Dianthi 15-35 part, Herba Polygoni Avicularis 15-35 part, Fructus Gardeniae 15-35 part, Radix Glycyrrhizae 15-45 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
CN201210204225.XA 2012-06-20 2012-06-20 Compound propolis composition used for treating broiler ascites syndrome, and preparation method thereof Expired - Fee Related CN102727694B (en)

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* Cited by examiner, † Cited by third party
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CN102973859B (en) * 2012-11-22 2014-05-21 青岛绿曼生物工程有限公司 Compound propolis composition for treating skin phthiriasis in livestock, and preparation method thereof
CN103877544B (en) * 2014-03-15 2016-08-17 青岛众志合才智能科技有限公司 Chinese medicine composition for the treatment of broiler ascites syndrome and preparation method thereof

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1164346A (en) * 1997-04-10 1997-11-12 韩尚君 Super concentrated fodder for ruminant

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1164346A (en) * 1997-04-10 1997-11-12 韩尚君 Super concentrated fodder for ruminant

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周大胜.《中药治肉鸡腹水病效果好》.《农村百事通》.2010,(第16期),49.
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