CN102727769A - Pure Chinese herbal composition for treating white scour of piglets - Google Patents

Abstract

The invention relates to a pure Chinese herbal composition for treating white scour of piglets. The composition is prepared by mixing the following components by weight: 15 to 35 parts of atractylodes rhizome, 10 to 20 parts of debark peony root, 10 to 35 parts of Chinese yam, 15 to 45 parts of oriental waterplantain rhizome, 15 to 45 parts of Chinese sorghum, 20 to 40 parts of Chinese gentian and 15 to 35 parts of liquorice root. The invention has the following beneficial effects: a reasonable recipe is formulated; preparation of the composition is simple; the pure Chinese herbal composition has no toxic and side effects, no drug residue and a substantial therapeutic effect; and according to clinical results, it is proved that the medicine has special efficacy on treating white scour of piglets.

Description

Pure Chinese medicine composition of treatment piglet pujos blancos and preparation method thereof

Technical field

The present invention relates to pure Chinese medicine composition of treating piglet pujos blancos and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to the treatment piglet pujos blancos and preparation method thereof.

Background technology

Piglet pujos blancos is that a kind of common alimentary infection that is caused by escherichia coli is sick, is characteristic with diarrhoea, ash discharge white, stench, paste shape loose stool clinically, and sickness rate is between 30%-80%, and mortality rate is more than 10%, and is very big to the harm of piglet.

The pathogen of primary disease is escherichia coli, and this disease spreads all over more than 100 countries of five continents, distributes very extensively.At present, treat this disease the most frequently used be various antibacterials, like oxytetracycline, chloromycetin, penicillin, streptomycin, quinolinones etc.; Because the prolonged and repeated use of antibacterials causes this pathogenic microorganism that medicine has been produced drug resistance, reduced curative effect, and drug residue in animal body, its meat does not reach nuisanceless requirement, has influenced the outlet of livestock products and people's health.

Therefore researching and developing a kind of specific medicament of treating piglet pujos blancos is one of this field scientific research technical staff new problem anxious to be solved.

Summary of the invention

The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, effect obviously, have no side effect, drug residue free, effectively treat pure Chinese medicine composition of piglet pujos blancos and preparation method thereof.

Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of pure Chinese medicine composition of treating piglet pujos blancos, by following component by weight mixed preparing form: Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part, Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part.

Said various component optimum ratio amount is: 25 parts of Rhizoma Atractylodis, 15 parts of the Radix Paeoniae Albas, 25 parts of Rhizoma Dioscoreaes, 30 parts of Rhizoma Alismatis, 30 parts of Sorghum vulgare Pers., 30 parts of Radix Gentianae, 25 parts in Radix Glycyrrhizae.

A kind of method for preparing of treating the pure Chinese medicine composition of piglet pujos blancos, carry out as follows:

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part by weight, mix 5-10 minute to even;

(3) take by weighing Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

The medicinal property of each component is following:

Rhizoma Atractylodis: hot, bitter, warm, return spleen, stomach, Liver Channel, the function that have drying damp and strengthening spleen, expelling wind and cold, makes eye bright; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold etc.

The Radix Paeoniae Alba: bitter,, acid, be slightly cold, return liver, spleen channel, have the suppressing the hyperactive liver pain relieving, a function of the yin fluid astringing that nourishes blood; Cure mainly deficiecny of liver-YIN, deficiency-heat, dysentery stomachache, spasm of the limbs etc.

Rhizoma Dioscoreae: sweet, flat, return spleen, stomach, lung meridian, have that spleen reinforcing nourishing the stomach, lung benefiting are promoted the production of body fluid, the function of the kidney invigorating arresting seminal emission; Cure mainly weakness of the spleen and stomach, inappetence, diarrhea due to hypofunction of the spleen, asthenia cough with asthma, spermatorrhea etc.

Rhizoma Alismatis: sweet, light, cold, return kidney, urinary bladder channel, have the function of diuresis, clearing away damp-heat; Cure mainly dysuria, edema distension, diarrhea due to damp-heat etc.

Sorghum vulgare Pers.: bitter, sweet, flat, return stomach, spleen, lung, intestinal warp, have the function of subduing swelling and detoxicating, promoting blood flow to regulate menstruation, stomach function regulating, removing food stagnancy, warming middle-JIAO, astringing intestine to stop diarrhea stomach, removing heat from blood; Cure mainly stagnation of dampness due to deficiency of the spleen, dyspepsia, damp-heat diarrhea, have blood in stool etc.

Radix Gentianae: bitter, cold, return liver, gallbladder meridian, have eliminating pathogen in the liver gallbladder excess-fire, remove the function of damp-heat in lower-JIAO; Cure mainly jaundice due to damp-heat, conjunctival congestion and swelling pain, eczema pruritus etc.

Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.

More than all flavor Chinese medicine according to the tcm theory compatible combination, to pathogenic microorganism and the clinical symptoms and the pathological change of piglet pujos blancos, bring into play the effect of treating both the principal and secondary aspects of a disease.

The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and the generation that has no drug resistance, cost is low, and it is wide to draw materials, the curative effect highly significant.Adopt pharmacology and the Chinese veterinarian of motherland determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs method, optimize this seven kinds of medicines, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves that the treatment piglet pujos blancos is had specially good effect.And make the livestock products meat reach nuisanceless requirement, satisfy the export standard of livestock products, guaranteed that effectively people's is healthy.

The specific embodiment

Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:

Embodiment 1

A kind of pure Chinese medicine composition of treating piglet pujos blancos and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing 150 parts of Rhizoma Atractylodis, 100 parts of the Radix Paeoniae Albas, 100 parts of Rhizoma Dioscoreaes by weight, mix 5-10 minute to even;

(3) take by weighing 150 parts of Rhizoma Alismatis, 150 parts of Sorghum vulgare Pers., 200 parts of Radix Gentianae, 150 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 2

A kind of pure Chinese medicine composition of treating piglet pujos blancos and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing 250 parts of Rhizoma Atractylodis, 150 parts of the Radix Paeoniae Albas, 150 parts of Rhizoma Dioscoreaes by weight, mix 5-10 minute to even;

(3) take by weighing 300 parts of Rhizoma Alismatis, 300 parts of Sorghum vulgare Pers., 300 parts of Radix Gentianae, 250 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 3

A kind of pure Chinese medicine composition of treating piglet pujos blancos and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing 350 parts of Rhizoma Atractylodis, 200 parts of the Radix Paeoniae Albas, 350 parts of Rhizoma Dioscoreaes by weight, mix 5-10 minute to even;

(3) take by weighing 450 parts of Rhizoma Alismatis, 450 parts of Sorghum vulgare Pers., 400 parts of Radix Gentianae, 350 parts in Radix Glycyrrhizae by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Clinical trial:

The clinical experiment animal selects for use 10-25 age in days, body weight at 6.5kg-15kg, and laboratory is diagnosed as the ill piglet of piglet pujos blancos.Ill piglet is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, and 20 every group, 3 groups of feeding environments are identical, and experiment was carried out 5 days altogether; The blank group is left intact, and the medicine matched group uses treatment with " piglet pujos blancos looses " by specification; Chinese medicine composition group of the present invention can be with the ill piglet of product feeding of the present invention etc., and a day dose is: pig is by per kilogram of body weight 0.2-0.45g, and spice is fed, every day 3 times, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal is counted x100%.Result's (testing the 5th day) when following table is the experiment end.

Table is the situation contrast of the present invention and other medicines treatment piglet pujos blancos:

Numbering	Group	Mortality rate %	Cure rate %	Symptom rate % is arranged during end
					I	The blank group	16.7	43.3	40.0
II	Piglet pujos blancos looses and organizes	6.7	76.6	16.7
					III	Chinese medicine composition of the present invention	3.3	86.7	10.0

This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with piglet pujos blancos and compared significant difference (P＜0.05).

Safety testing:

Choose 10 of 70 age in days health pig; 5 times of spices according to the embodiment of the invention 1 made compositions RD were fed 10 days; During the medication; Health pig has no bad or Deviant Behavior performance, and the drinking-water of searching for food is normal, and it is not remarkable that weight increase and blank group (being not administration of health group) are compared difference.

Above-mentioned detailed description of pure Chinese medicine composition of this treatment piglet pujos blancos and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. pure Chinese medicine composition of treating piglet pujos blancos, it is characterized in that by following component by weight mixed preparing form: Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part, Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part.

2. the pure Chinese medicine composition of treatment piglet pujos blancos according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of Rhizoma Atractylodis, 15 parts of the Radix Paeoniae Albas, 25 parts of Rhizoma Dioscoreaes, 30 parts of Rhizoma Alismatis, 30 parts of Sorghum vulgare Pers., 30 parts of Radix Gentianae, 25 parts in Radix Glycyrrhizae.

3. the method for preparing of the pure Chinese medicine composition of a treatment piglet pujos blancos according to claim 1 and 2 is characterized in that carrying out as follows:

(1) composition of respectively distinguishing the flavor of in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing Rhizoma Atractylodis 15-35 part, Radix Paeoniae Alba 10-20 part, Rhizoma Dioscoreae 10-35 part by weight, mix 5-10 minute to even;

(3) take by weighing Rhizoma Alismatis 15-45 part, Sorghum vulgare Pers. 15-45 part, Radix Gentianae 20-40 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.