CN102397335B - Pure Chinese medicinal composition for treating poultry fatty liver haemorrhage syndrome and preparation method thereof - Google Patents

Abstract

The invention discloses a pure Chinese medicinal composition for treating a poultry fatty liver haemorrhage syndrome and a preparation method thereof, and relates to the field of animal medicines. The preparation method for the composition comprises the following steps of: (1) performing ultramicro grinding on various components in the formula respectively, and screening by using a 700-mesh sieve; (2) weighing 15 to 35 parts of propolis, 15 to 35 parts of Chinese thorowax root, 15 to 45 parts of virgate wormwood herb and 15 to 35 parts of indigowoad root according to weights, and uniformly mixing for 5 to 10 minutes; (3) weighing 15 to 45 parts of Chinese magnoliavine fruit, 15 to 45 parts of liquoric root, 15 to 45 parts of cassia seed and 15 to 45 parts of green bean according to the weights, and uniformly mixing for 5 to 10 minutes; and (4) mixing the compositions obtained in the steps (2) and (3), and uniformly mixing for 10 to 15 minutes continuously to obtain the composition. The composition has the advantages of reasonable formula, no pollution and extremely obvious curative effect and is easy to prepare; and clinical tests prove that: the composition has a special effect of treating the poultry fatty liver haemorrhage syndrome.

Description

A kind of syndromic pure Chinese medicine composition of poultry fat hepatorrhagia and preparation method thereof for the treatment of

Technical field

The present invention relates to the animal field of medicaments, particularly a kind of syndromic pure Chinese medicine composition of poultry fat hepatorrhagia and preparation method thereof for the treatment of.

Background technology

Poultry fat hepatorrhagia syndrome mainly betides the bird inlay of raising in cages, and clinically deposits significant quantities of fat, subcapsular hemorrhage of liver as feature in hepatocyte, is because the ability of liver synthctic fat has exceeded due to the transport capacity of lipoprotein.This disease all can occur throughout the year, and mortality rate is about 10%, and is very large to the harm on the occasion of the poultry of laying period.

At present, this disease does not also have good Therapeutic Method, and just adding choline chloride, vitamin B group, methionine etc. in feedstuff prevents primary disease.Poultry is morbidity in a single day, and medicine is not treated effectively, already causes very large loss for laying hen.

Therefore research and develop a kind of treat poultry fat hepatorrhagia syndrome and have no side effect, the specific medicament of drug residue free is one of this field scientific research technical staff new problem anxious to be resolved.

Summary of the invention

The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, effectively treat syndromic pure Chinese medicine composition of poultry fat hepatorrhagia and preparation method thereof.

Implementation of the present invention is as follows for achieving the above object: a kind of syndromic pure Chinese medicine composition of poultry fat hepatorrhagia for the treatment of, by following component by weight mixed preparing form: propolis 15-35 part, Radix Bupleuri 15-35 part, Herba Artemisiae Scopariae 15-45 part, Radix Isatidis 15-35 part, Fructus Schisandrae Chinensis 15-45 part, Radix Glycyrrhizae 15-45 part, Semen Cassiae 15-45 part, Semen phaseoli radiati 15-45 part.

Described various component optimum ratio amount is: 25 parts of propolis, 25 parts of Radix Bupleuri, 35 parts of Herba Artemisiae Scopariaes, 25 parts of Radix Isatidis, 30 parts of Fructus Schisandrae Chinensis, 30 parts in Radix Glycyrrhizae, 30 parts of Semen Cassiaes, 30 parts in Semen phaseoli radiati.

A kind of preparation method for the treatment of the syndromic pure Chinese medicine composition of poultry fat hepatorrhagia, carry out as follows:

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing by weight propolis 15-35 part, Radix Bupleuri 15-35 part, Herba Artemisiae Scopariae 15-45 part, Radix Isatidis 15-35 part, mix 5-10 minute to even;

(3) take by weighing by weight Fructus Schisandrae Chinensis 15-45 part, Radix Glycyrrhizae 15-45 part, Semen Cassiae 15-45 part, Semen phaseoli radiati 15-45 part, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

The medicinal property of each component is as follows:

Propolis: bitter, hot, cold, return spleen, stomach warp, have anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, improve the function of immunity, antiallergic oxidation, hemostasis, protection gastrointestinal mucosa etc.

Radix Bupleuri: hot, bitter, be slightly cold, return liver, gallbladder, lung meridian, have the function of delivering with inner, elevate a turnable ladder yang-energy, dispersing the stagnated live-QI to relieve the stagnation of QI; Cure mainly insufficiency of the spleen chronic diarrhea, stagnation of QI due to depression of the liver etc.

Herba Artemisiae Scopariae: bitter, hot, be slightly cold, return, spleen, stomach, gallbladder, Liver Channel, have the function of clearing away heat-damp and promoting diuresis, promoting the function of the gallbladder to alleviate jaundice; Cure mainly jaundice, oliguria, eczema pruritus etc.

Radix Isatidis: little hardship, sweet, return liver, kidney channel, have the function of eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome; Cure mainly rheumatic arthralgia, traumatic injury, stranguria with blood etc.

Cortex Acanthopancis: bitter, hot, warm, return liver, kidney channel, have the function of expelling wind and removing dampness, bone and muscle strengthening, liver and kidney tonifying, inducing diuresis to remove edema; Cure mainly anemofrigid-damp arthralgia, the waist flaccidity is soft, the deficiency of vital energy is weak, edema etc.

Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.

Semen phaseoli radiati: sweet, cool, GUIXIN, stomach warp have heat-clearing and toxic substances removing, a function of the stomach invigorating of relieving summer heat; Cure mainly diarrhea due to damp-heat, the detoxifcation protect the liver, antiallergic.

Radix Isatidis: bitter, cold, GUIXIN, stomach warp have the function of removing heat from blood sore-throat relieving, heat-clearing and toxic substances removing; Cure mainly laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison, maculae caused by violent heat pathogen.

Semen Cassiae: sweet, bitter, salty, be slightly cold, return liver, large intestine channel, have the function of liver heat removing and eyesight improving, loosening bowel to relieve constipation; Cure mainly wind-heat of liver channel, conjunctival congestion and swelling pain, feces dryness accumulated in the stomach and intestine etc.

Above all flavor Chinese medicine for the syndromic paathogenic factor of poultry fat hepatorrhagia and pathological change, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease according to the tcm theory compatible combination.

The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, draws materials wide the curative effect highly significant.Theoretical and the modern Chinese medicine pharmacology theory according to the tradition Chinese veterinarian of motherland, optimize this eight kinds of medicines, and making them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, treatment poultry fat hepatorrhagia syndrome is had specially good effect and has no side effect and drug resistance.And make poultry product reach nuisanceless requirement, satisfy the export standard of poultry product, guaranteed that effectively people's is healthy.

The specific embodiment

Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:

Embodiment 1

A kind of syndromic pure Chinese medicine composition of poultry fat hepatorrhagia and preparation method thereof for the treatment of: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing by weight 150 parts of propolis, 150 parts of Radix Bupleuri, 150 parts of Herba Artemisiae Scopariaes, 150 parts of Radix Isatidis, mix 5-10 minute to even;

(3) take by weighing by weight 150 parts of Fructus Schisandrae Chinensis, 150 parts in Radix Glycyrrhizae, 150 parts of Semen Cassiaes, 150 parts in Semen phaseoli radiati, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 2

A kind of syndromic pure Chinese medicine composition of poultry fat hepatorrhagia and preparation method thereof for the treatment of: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing by weight 250 parts of honeybee propolis, 250 parts of Radix Bupleuri, 300 parts of Herba Artemisiae Scopariaes, 250 parts of Radix Isatidis, mix 5-10 minute to even;

(3) take by weighing by weight 300 parts of Fructus Schisandrae Chinensis, 300 parts in Radix Glycyrrhizae, 300 parts of Semen Cassiaes, 300 parts in Semen phaseoli radiati, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 3

A kind of syndromic pure Chinese medicine composition of poultry fat hepatorrhagia and preparation method thereof for the treatment of: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing by weight 350 parts of propolis, 350 parts of Radix Bupleuri, 450 parts of Herba Artemisiae Scopariaes, 350 parts of Radix Isatidis, mix 5-10 minute to even;

(3) take by weighing by weight 450 parts of Fructus Schisandrae Chinensis, 450 parts in Radix Glycyrrhizae, 450 parts of Semen Cassiaes, 450 parts in Semen phaseoli radiati, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Clinical trial:

With the ill poultry of product feeding of the present invention, a day dose is: per 100 restrain 210 kilograms of present composition spices feeds or drinks water 380 kilograms, every day 2-3 time; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.

Table is the present invention and the applicable cases contrast of the syndromic field of other medicines treatment poultry fat hepatorrhagia:

Numbering	Group	Mortality rate %	Cure rate %	Symptom rate % is arranged during end
					I	The blank group	12.1	60.4	27.5
II	The loose group of JIANGZHILING	9.6	79.8	10.6
					III	Chinese medicine composition group of the present invention	6.0	88.8	5.2

This clinical effectiveness statistical analysis, present composition group is being compared significant difference (P＜0.05) with the loose group of JIANGZHILING aspect the cure rate.

Above-mentioned detailed description of syndromic pure Chinese medicine composition of this treatment poultry fat hepatorrhagia and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; because of than in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. treatment poultry fat hepatorrhagia syndromic pure Chinese medicine composition, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Radix Bupleuri 15-35 part, Herba Artemisiae Scopariae 15-45 part, Radix Isatidis 15-35 part, Fructus Schisandrae Chinensis 15-45 part, Radix Glycyrrhizae 15-45 part, Semen Cassiae 15-45 part, Semen phaseoli radiati 15-45 part.

2. the syndromic pure Chinese medicine composition for the treatment of poultry fat hepatorrhagia according to claim 1 is characterized in that described various component optimum ratio amount is: 25 parts of propolis, 25 parts of Radix Bupleuri, 35 parts of Herba Artemisiae Scopariaes, 25 parts of Radix Isatidis, 30 parts of Fructus Schisandrae Chinensis, 30 parts in Radix Glycyrrhizae, 30 parts of Semen Cassiaes, 30 parts in Semen phaseoli radiati.

3. the preparation method of the syndromic pure Chinese medicine composition for the treatment of poultry fat hepatorrhagia according to claim 1 is characterized in that carrying out as follows:

(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;

(2) take by weighing by weight propolis 15-35 part, Radix Bupleuri 15-35 part, Herba Artemisiae Scopariae 15-45 part, Radix Isatidis 15-35 part, mix 5-10 minute to even;

(3) take by weighing by weight Fructus Schisandrae Chinensis 15-45 part, Radix Glycyrrhizae 15-45 part, Semen Cassiae 15-45 part, Semen phaseoli radiati 15-45 part, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.