CN102499970B - Pure Chinese medicinal composition for treating bovine grainsick and preparation method thereof - Google Patents
Pure Chinese medicinal composition for treating bovine grainsick and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pure Chinese medicinal composition for treating bovine grainsick and a preparation method thereof, and relates to the field of animal medicines. The preparation method comprises the following steps of: (1) performing ultramicro crushing on all components in a formula, and sieving with a 700-mesh sieve; (2) weighing 10 to 25 weight parts of baical skullcap root, 15 to 45 weight parts of rhubarb, 25 to 55 weight parts of mirabilite, 15 to 30 weight parts of immature bitter orange and 15 to 30 weight parts of morning glory seed, and mixing for 5 to 10 minutes; (3) weighing 15 to 35 weight parts of talc, 15 to 45 weight parts of cannabis fruit, 10 to 30 weight parts of liquoric root, 10 to 25 weight parts of charred triplet and 10 to 35 weight parts of akebia stem, and mixing for 5 to 10 minutes; and (4) mixing compositions prepared in the steps (2) and (3), and mixing uniformly for 10 to 15 minutes. According to the pure Chinese medicinal composition, multiple pure Chinese medicines are adopted, so the pure Chinese medicinal composition has the unique advantage which western medicines do not have; and the pure Chinese medicinal composition is reasonable in formula, does not have toxic or side effect, is easy to prepare, pollution-free, low in cost and high in bioavailability, is prepared by ultramicro crushing and has an obvious curative effect.
Description
Technical field
The present invention relates to the animal field of medicaments, particularly relate to a kind of pure Chinese medicine composition for the treatment of bovine rumen impaction and preparation method thereof.
Background technology
Bovine rumen impaction is that cattle searches for food and a large amount of hold expansive feedstuff, thick and stiff heavy Radix Glycyrrhizae, surfeit or eat steathily a large amount of concentrates etc., or usage is overweight etc., in the stagnant cud of food, the intense stimulus coat of the stomach, rumen peristalsis dies down gradually, makes glandular stomach be slow state, and food expands but the cud expansion, gastric content exsiccation hardening, form grainsick.Can jeopardize the life of cattle when grainsick is serious, be to cause one of disease that the domestic animal economic loss is more serious.
Current medicine effect is outstanding not, and with western medicine, because of its pharmacological action, strong and toxic and side effects reaches more greatly that curative effect is poor is restricted its clinical practice.Therefore researching and developing a kind of specific medicament for the treatment of bovine rumen impaction is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, have no side effect, effectively treat pure Chinese medicine composition of bovine rumen impaction and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of bovine rumen impaction, by following component by weight mixed preparing form: 10~25 parts of Radix Scutellariaes, 15~45 parts of Radix Et Rhizoma Rhei, 25~55 parts, Natrii Sulfas, 15~30 parts of Fructus Aurantii Immaturuss, 15~30 parts of Semen Pharbitidis, 15~35 parts, Talcum, 15~45 parts of Fructus Cannabis, 10~30 parts, Radix Glycyrrhizae, 10~25 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10~35 parts of Caulis Akebiaes.
On the basis of such scheme, described various component optimum ratio amounts are: 15 parts of Radix Scutellariaes, 30 parts of Radix Et Rhizoma Rhei, 40 parts, Natrii Sulfas, 25 parts of Fructus Aurantii Immaturuss, 25 parts of Semen Pharbitidis, 25 parts, Talcum, 30 parts of Fructus Cannabis, 20 parts, Radix Glycyrrhizae, 15 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 25 parts of Caulis Akebiaes.
A kind of preparation method for the treatment of the pure Chinese medicine composition of bovine rumen impaction, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take 10~25 parts of Radix Scutellariaes, 15~45 parts of Radix Et Rhizoma Rhei, 25~55 parts, Natrii Sulfas, 15~30 parts of Fructus Aurantii Immaturuss, 15~30 parts of Semen Pharbitidis by above-mentioned parts by weight proportioning, mix 5~10 minutes, to even;
(3) take 15~35 parts, Talcum, 15~45 parts of Fructus Cannabis, 10~30 parts, Radix Glycyrrhizae, 10~25 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10~35 parts of Caulis Akebiaes by above-mentioned parts by weight proportioning, mix 5~10 minutes, to even;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10~15 minutes, mix homogeneously.
The medicinal property of each component is as follows:
Radix Scutellariae: bitter, cold, return lung, gallbladder, spleen, large intestine, small intestine meridian, there is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive function; Cure mainly that cough due to lung-heat, gastrointestinal are damp and hot, dysentery, jaundice, high heat are greedyly drunk, have blood in stool, epistaxis, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus, frequent fetal movement etc.
Radix Et Rhizoma Rhei: bitter, cold, return large intestine, spleen, stomach, liver, pericardium channel, there is the function of purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, removing mass blood stasis expelling; Cure mainly excess-heat constipation, combined symptoms, the yellow furunculosis of skin ulcer, conjunctival congestion and swelling pain, enteritis etc.
Natrii Sulfas: bitter, become, cold, return stomach, large intestine channel, there is the function of purging heat to relax the bowels, moistening for dryness and softening hard mass, clearing heat for detumescence, cure mainly excess-heat constipation, feces dryness accumulated in the stomach and intestine, acute mastitis and swell and ache etc.
Fructus Aurantii Immaturus: bitter, hot, acid, warm, return spleen, stomach warp, there is the dispelling the stagnated QI removing food stagnancy, reduce phlegm, the function of de-swelling; Cure mainly that food stagnation does not disappear, tripe is swollen, feces is constipated, hang down de-disease, the stagnant vapour lock of expectorant etc.
Semen Pharbitidis: bitter, cold, return spleen, stomach warp, there is the removing water retention by purgation relieving constipation, drink, the long-pending function of parasite killing merit are washed in expectorant; Cure mainly that edema distension, constipation and anuresis, phlegm retention gather, QI rising in reverse order is breathed with cough etc.
Talcum: sweet, light, cold, return bladder, stomach, lung meridian, there is the function of inducing diuresis for treating stranguria syndrome, clearing away summer-heat; Cure mainly pyretic stranguria, stranguria caused by urinary stone, diarrhea due to damp-heat, summer-heat, eczema, eczema etc.
Fructus Cannabis: sweet, cold, return large intestine channel, there is the function of loosening bowel to relieve constipation, removing toxic substances and promoting granulation; Cure mainly dryness of the intestine constipation etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata): sweet, sour, return stomach, small intestinal, large intestine channel, there is the function of dyspepsia and intestinal stasis relieving, invigorating the spleen and stomach; Curing mainly feeling of stuffiness in chest abdominal distention, distension and fullness in the abdomen, belch, food stagnation does not disappear etc.
Caulis Akebiae: light, bitter, cold, GUIXIN, lung, small intestinal, urinary bladder channel, have clearing away heat and promoting diuresis, a function of the stimulating milk secretion of stimulating the menstrual flow; Cure mainly damp-heat in the urinary bladder, edema, difficulty in urination etc.
Above all flavor Chinese medicine, according to the tcm theory compatible combination, for the various paathogenic factors that cause bovine rumen impaction, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, and cost is low, draws materials wide, has no side effect, and micronizing, bioavailability are high, the curative effect highly significant.According to the tradition Chinese veterinarian of motherland theory, optimize this ten herbal medicine, and make them according to best proportioning, form compound preparation, clinical practice proves that the treatment bovine rumen impaction is had to specially good effect.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of bovine rumen impaction and preparation method thereof, carry out: (every part by 10g) as follows
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) proportioning takes 100 parts of Radix Scutellariaes, 150 parts of Radix Et Rhizoma Rhei, 250 parts, Natrii Sulfas, 150 parts of Fructus Aurantii Immaturuss, 150 parts of Semen Pharbitidis by weight, mixes 5~10 minutes, to even;
(3) proportioning takes 150 parts, Talcum, 150 parts of Fructus Cannabis, 100 parts, Radix Glycyrrhizae, 100 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 100 parts of Caulis Akebiaes by weight, mixes 5~10 minutes, to even;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10~15 minutes, mix homogeneously.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of bovine rumen impaction and preparation method thereof, carry out: (every part by 10g) as follows
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) proportioning takes 150 parts of Radix Scutellariaes, 300 parts of Radix Et Rhizoma Rhei, 400 parts, Natrii Sulfas, 250 parts of Fructus Aurantii Immaturuss, 250 parts of Semen Pharbitidis by weight, mixes 5~10 minutes, to even;
(3) proportioning takes 250 parts, Talcum, 300 parts of Fructus Cannabis, 200 parts, Radix Glycyrrhizae, 150 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 150 parts of Caulis Akebiaes by weight, mixes 5~10 minutes, to even;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10~15 minutes, mix homogeneously.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of bovine rumen impaction and preparation method thereof, carry out: (every part by 10g) as follows
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) proportioning takes 250 parts of Radix Scutellariaes, 450 parts of Radix Et Rhizoma Rhei, 550 parts, Natrii Sulfas, 300 parts of Fructus Aurantii Immaturuss, 300 parts of Semen Pharbitidis by weight, mixes 5~10 minutes, to even;
(3) proportioning takes 350 parts, Talcum, 450 parts of Fructus Cannabis, 300 parts, Radix Glycyrrhizae, 250 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 350 parts of Caulis Akebiaes by weight, mixes 5~10 minutes, to even;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10~15 minutes, mix homogeneously.
Clinical trial:
Product warm water of the present invention is gavaged, and each 200 grams-500 gram, every day 1 time, be used in conjunction 2-3 time; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.
Table is the situation of applying clinically traditional Chinese medicine composition for treating bovine rumen impaction of the present invention:
Numbering | Group | Case fatality rate % | Cure rate % | Symptom rate % is arranged during end |
I | The blank group | 10.5 | 62.3 | 27.2 |
II | Help digestion loose group | 5.4 | 83.0 | 11.6 |
III | Present composition group | 1.0 | 94.1 | 4.9 |
This clinical effectiveness statistical analysis, present composition treatment group is being compared difference extremely significantly (P<0.01) with the loose group that helps digestion aspect cure rate.
Above-mentioned detailed description of pure Chinese medicine composition of this treatment bovine rumen impaction and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (3)
1. a pure Chinese medicine composition for the treatment of bovine rumen impaction, it is characterized in that by following component by weight mixed preparing form: 10~25 parts of Radix Scutellariaes, 15~45 parts of Radix Et Rhizoma Rhei, 25~55 parts, Natrii Sulfas, 15~30 parts of Fructus Aurantii Immaturuss, 15~30 parts of Semen Pharbitidis, 15~35 parts, Talcum, 15~45 parts of Fructus Cannabis, 10~30 parts, Radix Glycyrrhizae, 10~25 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10~35 parts of Caulis Akebiaes.
2. the pure Chinese medicine composition for the treatment of bovine rumen impaction according to claim 1, it is characterized in that by following component by weight mixed preparing form: 15 parts of Radix Scutellariaes, 30 parts of Radix Et Rhizoma Rhei, 40 parts, Natrii Sulfas, 25 parts of Fructus Aurantii Immaturuss, 25 parts of Semen Pharbitidis, 25 parts, Talcum, 30 parts of Fructus Cannabis, 20 parts, Radix Glycyrrhizae, 15 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 25 parts of Caulis Akebiaes.
3. the preparation method of the pure Chinese medicine composition of a treatment bovine rumen impaction according to claim 1 is characterized in that carrying out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after micronizing respectively;
(2) take 10~25 parts of Radix Scutellariaes, 15~45 parts of Radix Et Rhizoma Rhei, 25~55 parts, Natrii Sulfas, 15~30 parts of Fructus Aurantii Immaturuss, 15~30 parts of Semen Pharbitidis by above-mentioned parts by weight proportioning, mix 5~10 minutes, to even;
(3) take 15~35 parts, Talcum, 15~45 parts of Fructus Cannabis, 10~30 parts, Radix Glycyrrhizae, 10~25 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10~35 parts of Caulis Akebiaes by above-mentioned parts by weight proportioning, mix 5~10 minutes, to even;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10~15 minutes, mix homogeneously.
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CN104436062A (en) * | 2014-12-15 | 2015-03-25 | 青岛百瑞吉生物工程有限公司 | Traditional Chinese medicine composition for treating bovine grainsick and preparation method of traditional Chinese medicine composition |
CN106938017A (en) * | 2017-03-24 | 2017-07-11 | 上林县山水牛畜牧业有限公司 | A kind of composition for preventing and treating rumen indigestion and preparation method thereof |
CN107468861A (en) * | 2017-09-28 | 2017-12-15 | 贵州梵净山农业高科技股份有限公司 | A kind of medicine for treating rumen indigestion and preparation method thereof |
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李玉文, 董在坤.防治奶牛瘤胃积食的体会.《中国兽医杂志》.2009,第45卷(第3期),74-75. |
防治奶牛瘤胃积食的体会;李玉文, 董在坤;《中国兽医杂志》;20090331;第45卷(第3期);74-75 * |
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